BGC0002012: julichrome Q3-3 biosynthetic gene cluster from Streptomyces afghaniensis 772
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Location: 8,349 - 34,051 nt. (total: 25,703 nt).
This entry is originally from NCBI GenBank NZ_KE354310.1.

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core biosynthetic genes
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Gene details
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0002012
Short description julichrome Q3-3 biosynthetic gene cluster from Streptomyces afghaniensis 772
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: NZ_KE354310.1
Compounds
  • julichrome Q3-3
  • julichrome Q3-5
Species Streptomyces afghaniensis 772 [taxonomy]
References
Chemical products information
julichrome Q3-3
(no structure information available)
julichrome Q3-5
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • STAFG_RS30595
  • WP_037671479.1
 8349 - 8765 (-) transcriptional repressor
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  • STAFG_RS30600
  • WP_020275079.1
 8912 - 9304 (-) CBS domain-containing protein
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  • STAFG_RS30605
  • WP_020275080.1
  • hisN
 9482 - 10282 (-) histidinol-phosphatase
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  • STAFG_RS30610
  • WP_037671481.1
 10486 - 11094 (+) TetR/AcrR family transcriptional regulator
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  • STAFG_RS30615
  • WP_020275082.1
 11102 - 11425 (-) multidrug efflux SMR transporter
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  • STAFG_RS30620
  • WP_020275083.1
  • rsgA
 11573 - 12583 (-) ribosome small subunit-dependent GTPase A
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  • STAFG_RS30625
  • WP_020275084.1
  • aroA
 12601 - 13917 (-) 3-phosphoshikimate 1-carboxyvinyltransferase
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  • STAFG_RS30630
  • WP_020275085.1
 14015 - 14749 (-) M50 family metallopeptidase
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  • STAFG_RS30635
  • WP_020275086.1
 14921 - 15775 (-) NAD(P)H-binding protein
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  • STAFG_RS30640
  • WP_020275087.1
 15856 - 17316 (-) FAD-dependent oxidoreductase
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  • STAFG_RS30645
  • WP_020275088.1
 17501 - 18709 (-) hypothetical protein
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  • STAFG_RS30650
  • WP_020275089.1
 18706 - 19713 (-) LLM class F420-dependent oxidoreductase
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  • STAFG_RS30655
  • WP_020275090.1
 19725 - 20951 (-) cytochrome P450
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  • STAFG_RS30660
  • WP_037671485.1
 21126 - 21830 (-) TetR/AcrR family transcriptional regulator C-terminal domain-containing protein
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  • STAFG_RS30665
  • WP_020275092.1
 22080 - 23543 (+) MFS transporter
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  • STAFG_RS30670
  • WP_082320004.1
 23910 - 24716 (+) response regulator transcription factor
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  • STAFG_RS50090
  • WP_020275094.1
 24974 - 25645 (+) TcmI family type II polyketide cyclase
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  • STAFG_RS30680
  • WP_020275095.1
 25642 - 26913 (+) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
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  • STAFG_RS30685
  • WP_037671486.1
 26910 - 28103 (+) ketosynthase chain-length factor
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  • STAFG_RS30690
  • WP_020275097.1
 28184 - 28447 (+) acyl carrier protein
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  • STAFG_RS30695
  • WP_020275098.1
 28500 - 29285 (+) SDR family NAD(P)-dependent oxidoreductase
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  • STAFG_RS30700
  • WP_020275099.1
 29314 - 30264 (+) aromatase/cyclase
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  • STAFG_RS30705
  • WP_020275100.1
 30261 - 31169 (+) alpha/beta hydrolase
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  • STAFG_RS30710
  • WP_020275101.1
 31166 - 31567 (+) lipocalin-like domain-containing protein
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  • STAFG_RS54195
  • WP_167338033.1
 31564 - 31755 (+) hypothetical protein
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  • STAFG_RS48165
  • WP_020275103.1
 31752 - 32486 (+) 4'-phosphopantetheinyl transferase superfamily protein
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  • STAFG_RS30725
  • WP_020275104.1
 32578 - 33393 (+) SOS response-associated peptidase
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  • STAFG_RS30730
  • WP_037671504.1
 33404 - 34051 (+) hydrolase
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: CUSGWVK3I4TVHJH7NHPFAP2L, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Fixed DOIs
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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