BGC0002015: aborycin biosynthetic gene cluster from Streptomyces sp. ZS0098
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Location: 18,549 - 30,566 nt. (total: 12,018 nt).
This entry is originally from NCBI GenBank NZ_MKCP01000039.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002015
Short description aborycin biosynthetic gene cluster from Streptomyces sp. ZS0098
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP
Loci NCBI GenBank: NZ_MKCP01000039.1
Compounds
  • aborycin
Species Streptomyces sp. ZS0098 [taxonomy]
References
Chemical products information
aborycin [synonyms: Siamycin III, L-Cysteinyl-L-leucylglycyl-L-isoleucylglycyl-L-seryl-L-cysteinyl-L-asparaginyl-L-alpha-aspartyl-L-phenylalanyl-L-alanylglycyl-L-cysteinylglycyl-L-tyrosyl-L-alanyl-L-valyl-L-valyl-L-cysteinyl-L-phenylalanyl-L-tryptophen cyclic(9-1)-peptid]
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C97H131N23O26S4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BIU87_RS24165
  • WP_147474396.1
 18549 - 19250 (-) response regulator transcription factor
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  • BIU87_RS24170
  • WP_122215938.1
 19732 - 20871 (+) sensor histidine kinase
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  • BIU87_RS24175
  • WP_183153327.1
 20982 - 21884 (+) ATP-binding cassette domain-containing protein
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  • BIU87_RS24180
  • WP_102640375.1
 21877 - 22629 (+) ABC transporter permease
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  • BIU87_RS24185
  • WP_106963308.1
 22746 - 22874 (+) aborycin family tricyclic lasso peptide
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  • BIU87_RS24190
  • WP_122215940.1
 22936 - 24747 (+) lasso peptide isopeptide bond-forming cyclase
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  • BIU87_RS24195
  • WP_037640857.1
 24744 - 25007 (+) lasso peptide biosynthesis PqqD family chaperone
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  • BIU87_RS24200
  • WP_122215941.1
 25004 - 25429 (+) lasso peptide biosynthesis B2 protein
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  • BIU87_RS24205
  • WP_122215942.1
 25426 - 26391 (+) ATP-binding cassette domain-containing protein
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  • BIU87_RS24210
  • WP_122215943.1
 26388 - 27257 (+) ABC transporter permease
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  • BIU87_RS24215
  • WP_122215944.1
 27271 - 27744 (+) DoxX family membrane protein
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  • BIU87_RS24220
  • WP_122215945.1
 27747 - 28472 (+) thioredoxin domain-containing protein
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  • BIU87_RS24225
  • WP_122215946.1
  • mslH
 28469 - 29815 (+) lasso peptide C-terminal Trp epimerase
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  • BIU87_RS24230
  • WP_122215947.1
 29889 - 30566 (+) response regulator transcription factor
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Cleaned up synonym list
  • Fetch compound properties from PubChem
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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