BGC0002096: tetrachlorizine biosynthetic gene cluster from Streptomyces sp. AJS327
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Location: 347,100 - 382,500 nt. (total: 35,401 nt).
This entry is originally from NCBI GenBank SKBR01000004.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002096
Short description tetrachlorizine biosynthetic gene cluster from Streptomyces sp. AJS327
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
SKBR01000004.1
347100 - 382500
via Enzymatic assays
Compounds
  • tetrachlorizine
Species Streptomyces sp. AJS327 [taxonomy]
References
Chemical products information
tetrachlorizine Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • E0L36_23525
  • MBA0053724.1
 347377 - 348384 (+) hypothetical protein
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    • E0L36_23530
    • MBA0053725.1
    		 348468 - 349397 (-) thioesterase
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      • E0L36_23535
      • MBA0053726.1
      		 349464 - 349721 (-) acyl carrier protein
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        • E0L36_23540
        • MBA0053727.1
        		 349933 - 350679 (-) 4'-phosphopantetheinyl transferase superfamily protein
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          • E0L36_23545
          • MBA0053728.1
          		 350676 - 352061 (-) cation/H(+) antiporter
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            • E0L36_23550
            • MBA0053729.1
            		 352355 - 353491 (+) acyl-CoA dehydrogenase
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              • E0L36_23555
              • MBA0053730.1
              		 353488 - 354960 (+) D-alanine--poly(phosphoribitol) ligase
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                • E0L36_23560
                • MBA0053731.1
                		 355081 - 355758 (-) response regulator transcription factor
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                  • E0L36_23565
                  • MBA0053732.1
                  		 356514 - 357155 (-) TetR/AcrR family transcriptional regulator
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                    • E0L36_23570
                    • MBA0053733.1
                    		 357182 - 357955 (-) ABC transporter permease
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                      • E0L36_23575
                      • MBA0053734.1
                      		 357955 - 358695 (-) ABC transporter ATP-binding protein
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                        • E0L36_23580
                        • MBA0053735.1
                        		 358881 - 360191 (-) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
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                          • E0L36_23585
                          • MBA0053736.1
                          		 360188 - 360463 (-) acyl carrier protein
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                            • E0L36_23590
                            • MBA0053737.1
                            		 360500 - 361933 (-) FAD-binding oxidoreductase
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                              • E0L36_23595
                              • MBA0053738.1
                              		 362059 - 363741 (-) hypothetical protein
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                                • E0L36_23600
                                • MBA0053739.1
                                		 363738 - 368285 (-) acyltransferase domain-containing protein
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                                  • E0L36_23605
                                  • MBA0053740.1
                                  		 368282 - 377395 (-) acyltransferase domain-containing protein
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                                    • E0L36_23610
                                    • MBA0053741.1
                                    		 377341 - 378687 (-) NAD(P)/FAD-dependent oxidoreductase
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                                      • E0L36_23615
                                      • MBA0053742.1
                                      		 378740 - 379924 (-) zinc-binding alcohol dehydrogenase family protein
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                                        • E0L36_23620
                                        • MBA0053743.1
                                        • fabI
                                        		 380076 - 380864 (-) enoyl-[acyl-carrier-protein] reductase FabI
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                                          • E0L36_23625
                                          • MBA0053744.1
                                          		 381028 - 381423 (+) hypothetical protein
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                                            • E0L36_23630
                                            • MBA0053745.1
                                            		 381784 - 382224 (-) MarR family transcriptional regulator
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                                              Biosynthesis information
                                              Annotation changelog

                                              Entry version: 2

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-10-07
                                              Added chemical structures for compounds: tetrachlorizine.
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              2022-10-07
                                              Added NPAtlas links to compounds: tetrachlorizine.
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 1

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-09-15
                                              Entry added
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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