BGC0002098: ECO-0501 biosynthetic gene cluster from Amycolatopsis keratiniphila
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Location: 3,150,830 - 3,251,873 nt. (total: 101,044 nt).
This entry is originally from NCBI GenBank CP003410.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002098
Short description ECO-0501 biosynthetic gene cluster from Amycolatopsis keratiniphila
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
CP003410.1
3150830 - 3251873
via Knock-out studies, Gene expression correlated with compound production
Compounds
  • ECO-0501
Species Amycolatopsis keratiniphila [taxonomy]
References
Chemical products information
ECO-0501 Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AORI_2931
  • AGM05517.1
 3150833 - 3151648 (-) putative multi-domain non-ribosomal peptide synthetase
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    • AORI_2932
    • AGM05518.1
    		 3151832 - 3152521 (+) hypothetical protein
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      • AORI_2933
      • AGM05519.1
      		 3152630 - 3154291 (+) tryptophan 2-monooxygenase
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        • AORI_2934
        • AGM05520.1
        		 3154355 - 3154894 (-) integral membrane protein
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          • AORI_2935
          • AGM05521.1
          		 3155072 - 3155740 (+) two-component system response regulator
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            • AORI_2936
            • AGM05522.1
            		 3155933 - 3157072 (-) signal transduction histidine kinase
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              • AORI_2937
              • AGM05523.1
              		 3157272 - 3158027 (+) thioesterase
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                • AORI_2938
                • AGM05524.1
                		 3158125 - 3158613 (-) hypothetical protein
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                  • AORI_2939
                  • AGM05525.1
                  • ugd
                  		 3158918 - 3160258 (+) UDPglucose 6-dehydrogenase
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                    • AORI_2940
                    • AGM05526.1
                    		 3160294 - 3161517 (+) hypothetical protein
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                      • AORI_2941
                      • AGM05527.1
                      		 3161522 - 3163087 (+) AMP-dependent synthetase and ligase
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                        • AORI_2942
                        • AGM05528.1
                        		 3163084 - 3164292 (+) 5-aminolevulinate synthase
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                          • AORI_2943
                          • AGM05529.1
                          • fadD
                          		 3164482 - 3166017 (+) long-chain acyl-CoA synthetase
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                            • AORI_2944
                            • AGM05530.1
                            		 3166119 - 3166466 (-) hypothetical protein
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                              • AORI_2945
                              • AGM05531.1
                              • aveA
                              		 3166497 - 3178001 (+) type I polyketide synthase
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                                • AORI_2946
                                • AGM05532.1
                                		 3178024 - 3195174 (+) beta-ketoacyl synthase
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                                  • AORI_2947
                                  • AGM05533.1
                                  		 3195178 - 3200385 (+) type I polyketide synthase
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                                    • AORI_2948
                                    • AGM05534.1
                                    		 3200710 - 3210504 (+) modular polyketide synthase
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                                      • AORI_2949
                                      • AGM05535.1
                                      • aveA
                                      		 3210531 - 3225830 (+) modular polyketide synthase
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                                        • AORI_2950
                                        • AGM05536.1
                                        		 3225844 - 3231609 (+) type I polyketide synthase
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                                          • AORI_2951
                                          • AGM05537.1
                                          		 3231893 - 3232816 (-) (acyl-carrier-protein)S-malonyltransferase-like protein
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                                            • AORI_2952
                                            • AGM05538.1
                                            		 3232821 - 3234251 (-) hypothetical protein
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                                              • AORI_2953
                                              • AGM05539.1
                                              		 3234268 - 3234477 (-) hypothetical protein
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                                                • AORI_2954
                                                • AGM05540.1
                                                		 3234491 - 3235255 (-) thioesterase
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                                                  • AORI_2955
                                                  • AGM05541.1
                                                  		 3235355 - 3235951 (-) hypothetical protein
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                                                    • AORI_2956
                                                    • AGM05542.1
                                                    		 3236016 - 3236855 (-) AraC family transcriptional regulator
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                                                      • AORI_2957
                                                      • AGM05543.1
                                                      		 3236895 - 3237713 (-) hypothetical protein
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                                                        • AORI_2958
                                                        • AGM05544.1
                                                        		 3237747 - 3238388 (-) lysine exporter protein LysE/YggA
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                                                          • AORI_2959
                                                          • AGM05545.1
                                                          		 3238458 - 3239522 (+) coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein
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                                                            • AORI_2960
                                                            • AGM05546.1
                                                            		 3239491 - 3240261 (-) hypothetical protein
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                                                              • AORI_2961
                                                              • AGM05547.1
                                                              		 3240366 - 3241193 (-) SAM-dependent methyltransferase
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                                                                • AORI_2962
                                                                • AGM05548.1
                                                                		 3241258 - 3241740 (+) hypothetical protein
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                                                                  • AORI_2963
                                                                  • AGM05549.1
                                                                  		 3241780 - 3242412 (+) hypothetical protein
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                                                                    • AORI_2964
                                                                    • AGM05550.1
                                                                    		 3242424 - 3243335 (-) hypothetical protein
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                                                                      • AORI_2965
                                                                      • AGM05551.1
                                                                      		 3243432 - 3244403 (+) AraC family transcriptional regulator
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                                                                        • AORI_2966
                                                                        • AGM05552.1
                                                                        		 3244455 - 3245165 (+) hypothetical protein
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                                                                          • AORI_2967
                                                                          • AGM05553.1
                                                                          		 3245660 - 3247291 (+) hypothetical protein
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                                                                            • AORI_2968
                                                                            • AGM05554.1
                                                                            		 3247300 - 3248646 (-) ABC transporter ATP-binding protein
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                                                                              • AORI_2969
                                                                              • AGM05555.1
                                                                              		 3248643 - 3249428 (-) peptide/nickel transport system permease protein
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                                                                                • AORI_2970
                                                                                • AGM05556.1
                                                                                		 3249422 - 3250363 (-) peptide/nickel transport system permease protein
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                                                                                  • AORI_2971
                                                                                  • AGM05557.1
                                                                                  		 3250365 - 3251873 (-) peptide/nickel transport system substrate-binding protein
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                                                                                    Biosynthesis information
                                                                                    Annotation changelog

                                                                                    Entry version: next

                                                                                    Date
                                                                                    Changes
                                                                                    Submitters
                                                                                    Reviewers
                                                                                    2024-08-10
                                                                                    MIBiG v4 annotathon
                                                                                    • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                    Entry version: 1

                                                                                    Date
                                                                                    Changes
                                                                                    Submitters
                                                                                    Reviewers
                                                                                    2022-09-15
                                                                                    Entry added
                                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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