BGC0002246: naematolin biosynthetic gene cluster from Hypholoma sublateritium FD-334 SS-4
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Location: 12,156 - 61,600 nt. (total: 49,445 nt).
This entry is originally from NCBI GenBank KN817616.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
Tailoring
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002246
Short description naematolin biosynthetic gene cluster from Hypholoma sublateritium FD-334 SS-4
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Unknown)
Loci
KN817616.1
12156 - 61600
via Heterologous expression
Compounds
  • naematolin
Species Hypholoma sublateritium FD-334 SS-4 [taxonomy]
References
Chemical products information
naematolin Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • HYPSUDRAFT_71160
  • KJA16696.1
 12156 - 14454 (-) hypothetical protein
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    • HYPSUDRAFT_47062
    • KJA16697.1
    		 14740 - 15385 (-) hypothetical protein
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      • HYPSUDRAFT_147346
      • KJA16698.1
      		 15682 - 20311 (+) hypothetical protein
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        • HYPSUDRAFT_147315
        • KJA16699.1
        		 21794 - 24122 (-) hypothetical protein
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          • HYPSUDRAFT_47067
          • KJA16700.1
          		 24971 - 25582 (-) hypothetical protein
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            • HYPSUDRAFT_47068
            • KJA16701.1
            		 26043 - 27702 (-) hypothetical protein
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              • HYPSUDRAFT_47071
              • KJA16702.1
              		 29760 - 31537 (+) hypothetical protein
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                • HYPSUDRAFT_58058
                • KJA16703.1
                		 32208 - 32998 (-) hypothetical protein
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                  • HYPSUDRAFT_192840
                  • KJA16704.1
                  		 33724 - 35851 (+) hypothetical protein
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                    • HYPSUDRAFT_1059497
                    • KJA16705.1
                    		 35947 - 36625 (-) hypothetical protein
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                      • HYPSUDRAFT_47075
                      • KJA16706.1
                      		 37223 - 38001 (-) hypothetical protein
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                        • HYPSUDRAFT_47076
                        • KJA16707.1
                        		 38552 - 40876 (-) hypothetical protein
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                          • HYPSUDRAFT_47078
                          • KJA16708.1
                          		 41449 - 43379 (+) hypothetical protein
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                            • HYPSUDRAFT_47080
                            • KJA16709.1
                            		 47061 - 48289 (+) hypothetical protein
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                              • HYPSUDRAFT_91134
                              • KJA16710.1
                              		 49171 - 49497 (-) hypothetical protein
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                                • HYPSUDRAFT_1059892
                                • KJA16711.1
                                		 49885 - 50908 (-) hypothetical protein
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                                  • HYPSUDRAFT_171124
                                  • KJA16712.1
                                  		 51267 - 52585 (-) hypothetical protein
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                                    • HYPSUDRAFT_47087
                                    • KJA16713.1
                                    		 54664 - 56444 (-) hypothetical protein
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                                      • HYPSUDRAFT_47089
                                      • KJA16714.1
                                      		 57045 - 58013 (+) hypothetical protein
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                                        • HYPSUDRAFT_47090
                                        • KJA16715.1
                                        		 58946 - 61437 (-) hypothetical protein
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                                          Biosynthesis information

                                          No biosynthesis information available for this record.

                                          Annotation changelog

                                          Entry version: 3

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2024-07-23
                                          MIBiG v4 annotathon
                                          • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Removed compounds: 5-β,6-α,8-β-trihydroxycariolan, 5-β,8-β-dihydroxycariolan, compound 3, compound 2.
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2022-10-07
                                          Added compounds: naematolin.
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2022-10-07
                                          Added NPAtlas links to compounds: naematolin.
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Entry added
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Tailoring functions
                                          Tailoring enzymes detected in this region
                                          Oxidoreductases: dehydrogenase oxidase oxygenase
                                          HYPSUDRAFT_171124: short-chain dehydrogenase/reductase SDR
                                          smcogs
                                          SMCOG1001: short-chain dehydrogenase/reductase SDR
                                          HYPSUDRAFT_47071: FAD linked oxidase domain protein
                                          smcogs
                                          SMCOG1138: FAD linked oxidase domain protein
                                          HYPSUDRAFT_47076: cytochrome P450
                                          smcogs
                                          SMCOG1034: cytochrome P450
                                          HYPSUDRAFT_47078: cytochrome P450
                                          smcogs
                                          SMCOG1034: cytochrome P450
                                          HYPSUDRAFT_47087: crotonyl-CoA reductase / alcohol dehydrogenase
                                          smcogs
                                          SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase
                                          HYPSUDRAFT_47089: short-chain dehydrogenase/reductase SDR
                                          smcogs
                                          SMCOG1001: short-chain dehydrogenase/reductase SDR
                                          HYPSUDRAFT_47090: cytochrome P450
                                          smcogs
                                          SMCOG1034: cytochrome P450
                                          Lyases: cyclase
                                          HYPSUDRAFT_47068: Terpene synthase/cyclase metal-binding domain protein
                                          smcogs
                                          SMCOG1052: Terpene synthase/cyclase metal-binding domain protein
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