BGC0002296: vatiamide A biosynthetic gene cluster from Moorena producens ASI16Jul14-2
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 97,932 nt. (total: 97,932 nt).
This entry is originally from NCBI GenBank MK618714.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002296
Short description vatiamide A biosynthetic gene cluster from Moorena producens ASI16Jul14-2
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
MK618714.1
1 - 97932
via Enzymatic assays
Compounds
  • vatiamide A
  • vatiamide B
  • vatiamide C
  • vatiamide D
  • vatiamide E
  • vatiamide F
Species Moorena producens ASI16Jul14-2 [taxonomy]
References
Chemical products information
vatiamide A Evidence:
Copy SMILES
Chemical database entries
NPAtlas
vatiamide B Evidence:
Copy SMILES
Chemical database entries
NPAtlas
vatiamide C Evidence:
Copy SMILES
Chemical database entries
NPAtlas
vatiamide D Evidence:
Copy SMILES
Chemical database entries
NPAtlas
vatiamide E Evidence:
Copy SMILES
Chemical database entries
NPAtlas
vatiamide F Evidence:
Copy SMILES
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QCP68979.1
1 - 1797 (+) VatA
    copy AA seq
    copy Nt seq
    • QCP68985.1
    1984 - 2949 (+) VatB
      copy AA seq
      copy Nt seq
      • QCP68990.1
      3091 - 3393 (+) VatC
        copy AA seq
        copy Nt seq
        • QCP68978.1
        3823 - 5874 (+) VatD
          copy AA seq
          copy Nt seq
          • QCP68972.1
          5931 - 11144 (+) VatE
            copy AA seq
            copy Nt seq
            • QCP68993.1
            11167 - 11406 (+) VatF
              copy AA seq
              copy Nt seq
              • QCP68982.1
              11540 - 12769 (+) VatG
                copy AA seq
                copy Nt seq
                • QCP68981.1
                12774 - 14033 (+) VatH
                  copy AA seq
                  copy Nt seq
                  • QCP68980.1
                  14408 - 15712 (+) VatI
                    copy AA seq
                    copy Nt seq
                    • QCP68987.1
                    15925 - 16689 (+) VatJ
                      copy AA seq
                      copy Nt seq
                      • QCP68965.1
                      16677 - 26510 (+) VatK
                        copy AA seq
                        copy Nt seq
                        • QCP68973.1
                        26522 - 31501 (+) VatL
                          copy AA seq
                          copy Nt seq
                          • QCP68968.1
                          31569 - 38132 (+) VatM
                            copy AA seq
                            copy Nt seq
                            • QCP68969.1
                            38129 - 44590 (+) VatN
                              copy AA seq
                              copy Nt seq
                              • QCP68986.1
                              44641 - 45456 (+) VatO
                                copy AA seq
                                copy Nt seq
                                • QCP68994.1
                                45498 - 45734 (+) VatP
                                  copy AA seq
                                  copy Nt seq
                                  • QCP68976.1
                                  45731 - 50479 (+) VatQ
                                    copy AA seq
                                    copy Nt seq
                                    • QCP68971.1
                                    50489 - 56176 (+) VatR
                                      copy AA seq
                                      copy Nt seq
                                      • QCP68975.1
                                      56545 - 61302 (+) VatS
                                        copy AA seq
                                        copy Nt seq
                                        • QCP68967.1
                                        61383 - 68165 (+) VatT
                                          copy AA seq
                                          copy Nt seq
                                          • QCP68970.1
                                          68220 - 74072 (+) VatU
                                            copy AA seq
                                            copy Nt seq
                                            • QCP68974.1
                                            74074 - 78906 (+) VatV
                                              copy AA seq
                                              copy Nt seq
                                              • QCP68966.1
                                              78914 - 87580 (+) VatW
                                                copy AA seq
                                                copy Nt seq
                                                • QCP68988.1
                                                88350 - 89009 (-) VatX
                                                  copy AA seq
                                                  copy Nt seq
                                                  • QCP68983.1
                                                  89744 - 90877 (-) putative hydrolase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • QCP68984.1
                                                    91856 - 92920 (+) hypothetical protein
                                                      copy AA seq
                                                      copy Nt seq
                                                      • QCP68992.1
                                                      93342 - 93599 (+) transposase
                                                        copy AA seq
                                                        copy Nt seq
                                                        • QCP68991.1
                                                        93568 - 93828 (+) transposase
                                                          copy AA seq
                                                          copy Nt seq
                                                          • QCP68989.1
                                                          93777 - 94334 (+) transposase
                                                            copy AA seq
                                                            copy Nt seq
                                                            • QCP68977.1
                                                            94465 - 97932 (-) response regulator
                                                              copy AA seq
                                                              copy Nt seq
                                                              Biosynthesis information

                                                              Biosynthetic modules

                                                              Name
                                                              Unk01
                                                              Type
                                                              nrps-type1
                                                              Genes
                                                              QCP68969.1
                                                              Substrates
                                                              tyrosine (evidence: Structure-based inference [2])
                                                              Integrated Monomers
                                                              Domains
                                                              adenylation
                                                              Name
                                                              Unk02
                                                              Type
                                                              nrps-type1
                                                              Genes
                                                              QCP68976.1
                                                              Substrates
                                                              alanine (evidence: Structure-based inference [2])
                                                              Integrated Monomers
                                                              Domains
                                                              adenylation
                                                              Name
                                                              Unk03
                                                              Type
                                                              nrps-type1
                                                              Genes
                                                              QCP68971.1
                                                              Substrates
                                                              valine (evidence: Structure-based inference [2])
                                                              Integrated Monomers
                                                              Domains
                                                              adenylation
                                                              Name
                                                              Unk04
                                                              Type
                                                              nrps-type1
                                                              Genes
                                                              QCP68975.1
                                                              Substrates
                                                              glycine (evidence: Structure-based inference [2])
                                                              Integrated Monomers
                                                              Domains
                                                              adenylation
                                                              Annotation changelog

                                                              Entry version: 1

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              Entry added
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              Added NRP substrate specificities
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              Similar known clusters from MIBiG 4.0
                                                              Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                              Detailed help and explanations are available here.

                                                              Click on reference genes to show details of similarities to genes within the current region.
                                                              Double click on a reference drawing to reverse the display of the genes.

                                                              Click on an accession to open that entry in the MIBiG database.


                                                              Location:

                                                              Identifier
                                                              Identity
                                                              Coverage
                                                              Detailed domain annotation
                                                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                              A domain glossary is available here, and an explanation of the visualisation is available here.
                                                              Selected features only
                                                              Show module domains