BGC0002377: WS9326B biosynthetic gene cluster from Streptomyces sp. SNM55
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Location: 1 - 58,067 nt. (total: 58,067 nt).
This entry is originally from NCBI GenBank MH243323.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002377
Short description WS9326B biosynthetic gene cluster from Streptomyces sp. SNM55
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
MH243323.1
1 - 58067
via
Compounds
  • WS9326B
  • WS9326A
  • WS9326G
  • WS9326F
Species Streptomyces sp. SNM55 [taxonomy]
References
Chemical products information
WS9326B Evidence:
(no structure information available)
WS9326A Evidence:
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Chemical database entries
NPAtlas
PubCHEM
WS9326G Evidence:
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Chemical database entries
NPAtlas
PubCHEM
ChemSpider
WS9326F Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QBA57759.1
 1 - 741 (-) hypothetical protein
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    • QBA57760.1
    		 826 - 1815 (-) thioesterase family protein
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      • QBA57729.1
      		 1918 - 2208 (+) LysR family transcriptional regulator
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        • QBA57730.1
        		 2255 - 2473 (+) MbtH family protein
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          • QBA57731.1
          		 2483 - 3268 (+) thioesterase
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            • QBA57761.1
            		 3334 - 4260 (-) hypothetical protein
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              • QBA57762.1
              		 4361 - 5353 (-) 3-oxoacyl-ACP synthase II
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                • QBA57763.1
                		 5350 - 6504 (-) 3-oxoacyl-ACP synthase II
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                  • QBA57767.1
                  		 6696 - 6971 (+) acyl carrier protein
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                    • QBA57732.1
                    		 6971 - 7342 (+) hypothetical protein
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                      • QBA57768.1
                      		 7333 - 7752 (+) hypothetical protein
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                        • QBA57733.1
                        		 7752 - 8174 (+) translation initiation factor IF-2
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                          • QBA57734.1
                          		 8171 - 9118 (+) 3-hydroxyacyl-ACP dehydratase
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                            • QBA57764.1
                            		 9174 - 9974 (-) hypothetical protein
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                              • QBA57765.1
                              		 10092 - 10289 (-) ferredoxin
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                                • QBA57766.1
                                		 10294 - 11517 (-) cytochrome P450
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                                  • QBA57735.1
                                  		 11792 - 19486 (+) NRPS
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                                    • QBA57736.1
                                    		 19490 - 27244 (+) NRPS
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                                      • QBA57737.1
                                      		 27241 - 36114 (+) NRPS
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                                        • QBA57738.1
                                        		 36140 - 36847 (+) thioesterase
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                                          • QBA57739.1
                                          		 36857 - 37681 (+) NAD(P)-dependent oxidoreductase
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                                            • QBA57740.1
                                            		 37714 - 40968 (+) NRPS
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                                              • QBA57741.1
                                              		 41014 - 42774 (+) NRPS
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                                                • QBA57742.1
                                                		 42771 - 43976 (+) ferredoxin reductase or FAD-dependent oxidoreductase
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                                                  • QBA57743.1
                                                  		 44213 - 45037 (+) alpha/beta hydrolase
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                                                    • QBA57744.1
                                                    		 45054 - 46055 (+) acyl-CoA thioesterase
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                                                      • QBA57745.1
                                                      		 46085 - 46816 (+) isomerase
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                                                        • QBA57746.1
                                                        		 46897 - 48609 (+) NAD(P)/FAD-dependent oxidoreductase
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                                                          • QBA57747.1
                                                          		 48758 - 49018 (+) acyl carrier protein
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                                                            • QBA57748.1
                                                            		 49129 - 50385 (+) 3-oxoacyl-ACP synthase
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                                                              • QBA57749.1
                                                              		 50388 - 51518 (+) 3-oxoacyl-ACP synthase
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                                                                • QBA57750.1
                                                                		 51521 - 52474 (+) 3-oxoacyl-ACP synthase
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                                                                  • QBA57751.1
                                                                  		 52526 - 53644 (+) 3-oxoacyl-ACP synthase
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                                                                    • QBA57752.1
                                                                    		 53686 - 53949 (+) acyl carrier protein
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                                                                      • QBA57753.1
                                                                      		 53946 - 54347 (+) 3-oxoacyl-ACP dehydratase
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                                                                        • QBA57754.1
                                                                        		 54341 - 54811 (+) 3-oxoacyl-ACP dehydratase
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                                                                          • QBA57755.1
                                                                          		 54841 - 55587 (+) 3-oxoacyl-reductase
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                                                                            • QBA57756.1
                                                                            		 55587 - 56126 (+) tRNA synthetase
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                                                                              • QBA57757.1
                                                                              		 56231 - 57187 (+) ABC transporter
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                                                                                • QBA57758.1
                                                                                		 57225 - 58067 (+) multidrug ABC transporter permease
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                                                                                  Biosynthesis information

                                                                                  Biosynthetic modules

                                                                                  Name
                                                                                  Unk01
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QBA57735.1
                                                                                  Substrates
                                                                                  threonine, serine (evidence: Structure-based inference [1])
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  Unk02
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QBA57735.1
                                                                                  Substrates
                                                                                  tyrosine (evidence: Structure-based inference, Homology)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  Unk03
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QBA57736.1
                                                                                  Substrates
                                                                                  leucine (evidence: Structure-based inference [1])
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  Unk04
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QBA57736.1
                                                                                  Substrates
                                                                                  phenylalanine (evidence: Structure-based inference [1])
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  Unk05
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QBA57737.1
                                                                                  Substrates
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  Unk06
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QBA57737.1
                                                                                  Substrates
                                                                                  serine (evidence: Structure-based inference [1])
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  Unk07
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QBA57740.1
                                                                                  Substrates
                                                                                  allo-threonine (evidence: Structure-based inference, Homology)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  Unk08
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QBA57741.1
                                                                                  Substrates
                                                                                  asparagine (evidence: Structure-based inference, Homology)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Annotation changelog

                                                                                  Entry version: 1

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2022-09-15
                                                                                  Entry added
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  2022-09-15
                                                                                  Added NRP substrate specificities
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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