BGC0002558: scopranone A biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 54,389 nt. (total: 54,389 nt).
This entry is originally from NCBI GenBank LC495479.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002558
Short description scopranone A biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
LC495479.1
1 - 54389
via Knock-out studies, Heterologous expression, Enzymatic assays
Compounds
  • scopranone A
  • scopranone B
  • scopranone C
Species Streptomyces sp. [taxonomy]
References
Chemical products information
scopranone A Evidence:
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Chemical database entries
NPAtlas
PubCHEM
scopranone B Evidence:
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Chemical database entries
NPAtlas
scopranone C Evidence:
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Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBM95943.1
 102 - 752 (-) transposase
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    • BBM95944.1
    		 1278 - 2357 (+) 5- methyltetrahydropteroyltriglutamtehomocysteineS- methyltransferase
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      • BBM95945.1
      		 3080 - 3382 (+) antibiotic biosynthesis monooxygenase
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        • BBM95946.1
        		 3813 - 4058 (-) hypothetical protein
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          • BBM95947.1
          • sprD
          		 3939 - 6662 (+) LuxR family transcriptional regulator
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            • BBM95948.1
            • sprE
            		 6713 - 7861 (-) acyl-CoA dehydrogenase
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              • BBM95949.1
              • sprF
              		 7881 - 8930 (-) F420-dependent oxidoreductase
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                • BBM95950.1
                • sprG
                		 8973 - 9734 (-) short chain dehydrogenase
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                  • BBM95951.1
                  • sprH
                  		 9782 - 10825 (-) 3-oxoacyl-ACP synthase
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                    • BBM95952.1
                    • sprI
                    		 11912 - 12529 (-) hypothetical protein
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                      • BBM95953.1
                      • sprJ
                      		 12531 - 14003 (-) MFS transporter protein
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                        • BBM95954.1
                        • sprK
                        		 14172 - 14576 (+) transcriptional regulator
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                          • BBM95955.1
                          • sprL
                          		 14874 - 16574 (+) acyl-CoA dehydrogenase
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                            • BBM95956.1
                            • sprM
                            		 16619 - 17911 (+) cytochrome P450
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                              • BBM95957.1
                              • sprN
                              		 17942 - 19195 (+) cytochrome P450
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                                • BBM95958.1
                                • sprO
                                		 19266 - 20612 (+) crotonyl-CoA reductase
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                                  • BBM95959.1
                                  • sprP
                                  		 20648 - 21640 (+) 3-oxoacyl-ACP synthase III
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                                    • BBM95960.1
                                    • sprQ
                                    		 21637 - 23010 (+) crotonyl-CoA reductase
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                                      • BBM95961.1
                                      • sprR
                                      		 23098 - 24039 (+) 3-oxoacyl-ACP synthase III
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                                        • BBM95962.1
                                        • sprS
                                        		 24036 - 24941 (+) 3-hydroxybutyryl-CoA dehydrogenase
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                                          • BBM95963.1
                                          • sprA
                                          		 25020 - 34040 (+) modular polyketide synthase
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                                            • BBM95964.1
                                            • sprB
                                            		 34054 - 38874 (+) modular polyketide synthase
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                                              • BBM95965.1
                                              • sprC
                                              		 38895 - 44474 (+) modular polyketide synthase
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                                                • BBM95966.1
                                                • sprT
                                                		 44471 - 45979 (+) monooxygenase
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                                                  • BBM95967.1
                                                  • sprU
                                                  		 46026 - 47594 (+) acyl-CoA carboxylase
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                                                    • BBM95968.1
                                                    		 47591 - 47854 (+) hypothetical protein
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                                                      • BBM95969.1
                                                      		 48307 - 48615 (-) IS1647-like transposase
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                                                        • BBM95970.1
                                                        		 48766 - 49011 (+) hypothetical protein
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                                                          • BBM95971.1
                                                          		 49124 - 49462 (+) hypothetical protein
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                                                            • BBM95972.1
                                                            		 49459 - 50391 (+) oxidoreductase
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                                                              • BBM95973.1
                                                              		 50728 - 51306 (-) TetR family transcriptional regulator
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                                                                • BBM95974.1
                                                                		 51400 - 51846 (+) membrane protein
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                                                                  • BBM95975.1
                                                                  		 52272 - 52826 (-) NAD(P)H-dependent FMN reductase
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                                                                    • BBM95976.1
                                                                    		 52986 - 54131 (-) monooxygenase
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                                                                      Biosynthesis information

                                                                      No biosynthesis information available for this record.

                                                                      Annotation changelog

                                                                      Entry version: 1

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2022-09-15
                                                                      Entry added
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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