BGC0002669: TVA-YJ-2 biosynthetic gene cluster from Streptomyces sp. NRRL S-87
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Location: 260,197 - 303,140 nt. (total: 42,944 nt).
This entry is originally from NCBI GenBank NZ_JOGB01000003.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002669
Short description TVA-YJ-2 biosynthetic gene cluster from Streptomyces sp. NRRL S-87
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
NZ_JOGB01000003.1
260197 - 303140
via Knock-out studies, Enzymatic assays
Compounds
  • TVA-YJ-2
Species Streptomyces sp. NRRL S-87 [taxonomy]
References
Chemical products information
TVA-YJ-2 Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • IF43_RS42015
  • WP_199922668.1
 260440 - 260601 (-) hypothetical protein
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    • IF43_RS0103380
    • WP_030193536.1
    		 261076 - 261360 (-) hypothetical protein
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      • IF43_RS0103390
      • WP_030193537.1
      • tadA
      		 261640 - 262068 (-) tRNA adenosine(34) deaminase TadA
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        • IF43_RS0103395
        • WP_030193538.1
        		 262149 - 262700 (-) hypothetical protein
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          • IF43_RS0103400
          • WP_030193539.1
          		 263137 - 263340 (-) hypothetical protein
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            • IF43_RS0103405
            • WP_030193540.1
            • upp
            		 263481 - 264116 (+) uracil phosphoribosyltransferase
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              • IF43_RS0103410
              • WP_037887244.1
              		 264121 - 264759 (-) LytR C-terminal domain-containing protein
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                • IF43_RS0103415
                • WP_003955420.1
                		 264864 - 265160 (-) type II toxin-antitoxin system VapB family antitoxin
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                  • IF43_RS0103420
                  • WP_030193546.1
                  		 265249 - 266880 (+) DUF853 family protein
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                    • IF43_RS0103425
                    • WP_030193548.1
                    • opcA
                    		 266893 - 267816 (-) glucose-6-phosphate dehydrogenase assembly protein OpcA
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                      • IF43_RS0103430
                      		 268013 - 268594 (-) Fe-S cluster assembly protein HesB
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                        • IF43_RS0103435
                        • WP_030193551.1
                        		 268716 - 269513 (+) VOC family protein
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                          • IF43_RS38895
                          		 269620 - >269872 (-) helix-turn-helix domain-containing protein
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                            • IF43_RS0103445
                            • WP_030193552.1
                            		 270109 - 270531 (-) PIN domain nuclease
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                              • IF43_RS0103450
                              • WP_030193554.1
                              		 270528 - 270743 (-) type II toxin-antitoxin system VapB family antitoxin
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                                • IF43_RS0103455
                                • WP_030193556.1
                                		 270838 - 273264 (-) helicase-associated domain-containing protein
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                                  • IF43_RS0103460
                                  • WP_234331921.1
                                  		 273588 - 274424 (-) hypothetical protein
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                                    • IF43_RS0103465
                                    • WP_030193560.1
                                    		 274571 - 275284 (-) C1 family peptidase
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                                      • IF43_RS0103470
                                      • WP_051794609.1
                                      		 275398 - 276276 (-) phytanoyl-CoA dioxygenase family protein
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                                        • IF43_RS0103475
                                        • WP_030193564.1
                                        		 276276 - 276965 (-) TfuA-like protein
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                                          • IF43_RS0103480
                                          • WP_030193566.1
                                          		 276980 - 278332 (-) YcaO-like family protein
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                                            • IF43_RS0103485
                                            • WP_234331922.1
                                            		 278370 - 279587 (-) 50S ribosomal protein L11 methyltransferase
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                                              • IF43_RS40350
                                              • WP_051794611.1
                                              		 279595 - 280200 (-) flavoprotein
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                                                • IF43_RS40355
                                                • WP_107048384.1
                                                		 280197 - 281141 (-) phosphotransferase
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                                                  • IF43_RS0103500
                                                  • WP_030193573.1
                                                  		 281138 - 282145 (-) T3SS effector HopA1 family protein
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                                                    • IF43_RS0103505
                                                    • WP_030193576.1
                                                    		 282142 - 283140 (-) phosphotransferase
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                                                      • IF43_RS0103510
                                                      • WP_107048385.1
                                                      • tvaA
                                                      		 283317 - 283580 (-) thioviridamide family RiPP peptide
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                                                        • IF43_RS0103520
                                                        • WP_030193583.1
                                                        		 284864 - 287137 (+) DNA polymerase III subunit gamma and tau
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                                                          • IF43_RS0103525
                                                          • WP_030193586.1
                                                          • purD
                                                          		 287198 - 288451 (+) phosphoribosylamine--glycine ligase
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                                                            • IF43_RS0103530
                                                            • WP_030193589.1
                                                            		 288770 - 290512 (+) membrane protein
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                                                              • IF43_RS0103535
                                                              • WP_234331923.1
                                                              		 290719 - 292278 (+) phosphoribosylamine--glycine ligase
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                                                                • IF43_RS0103540
                                                                • WP_030193595.1
                                                                		 292377 - 293282 (+) phosphoribosylaminoimidazolesuccinocarboxamide synthase
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                                                                  • IF43_RS0103550
                                                                  • WP_030193597.1
                                                                  		 293538 - 294179 (-) response regulator transcription factor
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                                                                    • IF43_RS0103555
                                                                    • WP_030193600.1
                                                                    		 294235 - 295497 (-) histidine kinase
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                                                                      • IF43_RS0103560
                                                                      • WP_030193602.1
                                                                      		 295521 - 296327 (-) ABC transporter permease
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                                                                        • IF43_RS0103565
                                                                        • WP_030193605.1
                                                                        		 296324 - 297283 (-) ABC transporter ATP-binding protein
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                                                                          • IF43_RS0103580
                                                                          • WP_030193607.1
                                                                          		 297800 - 298117 (-) Lsr2 family protein
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                                                                            • IF43_RS0103585
                                                                            • WP_037887251.1
                                                                            • purS
                                                                            		 298445 - 298696 (+) phosphoribosylformylglycinamidine synthase subunit PurS
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                                                                              • IF43_RS0103590
                                                                              • WP_030193612.1
                                                                              • purQ
                                                                              		 298699 - 299379 (+) phosphoribosylformylglycinamidine synthase subunit PurQ
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                                                                                • IF43_RS0103595
                                                                                • WP_030193614.1
                                                                                • purL
                                                                                		 299376 - 301625 (+) phosphoribosylformylglycinamidine synthase subunit PurL
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                                                                                  • IF43_RS0103600
                                                                                  • WP_030193616.1
                                                                                  		 301707 - 302498 (+) maleylpyruvate isomerase family mycothiol-dependent enzyme
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                                                                                    • IF43_RS0103605
                                                                                    • WP_051794613.1
                                                                                    		 302546 - 303034 (+) META domain-containing protein
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                                                                                      Biosynthesis information
                                                                                      Annotation changelog

                                                                                      Entry version: 1

                                                                                      Date
                                                                                      Changes
                                                                                      Submitters
                                                                                      Reviewers
                                                                                      2022-09-15
                                                                                      Entry added
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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