BGC0002669: TVA-YJ-2 biosynthetic gene cluster from Streptomyces sp. NRRL S-87
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Location: 260,197 - 303,140 nt. (total: 42,944 nt).
This entry is originally from NCBI GenBank NZ_JOGB01000003.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002669
Short description TVA-YJ-2 biosynthetic gene cluster from Streptomyces sp. NRRL S-87
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP
Loci NCBI GenBank: NZ_JOGB01000003.1
Compounds
  • TVA-YJ-2
Species Streptomyces sp. NRRL S-87 [taxonomy]
References
Chemical products information
TVA-YJ-2 [synonyms: thioholgamide A]
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • IF43_RS42015
  • WP_199922668.1
 260440 - 260601 (-) hypothetical protein
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  • IF43_RS0103380
  • WP_030193536.1
 261076 - 261360 (-) hypothetical protein
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  • IF43_RS0103390
  • WP_030193537.1
  • tadA
 261640 - 262068 (-) tRNA adenosine(34) deaminase TadA
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  • IF43_RS0103395
  • WP_030193538.1
 262149 - 262700 (-) hypothetical protein
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  • IF43_RS0103400
  • WP_030193539.1
 263137 - 263340 (-) hypothetical protein
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  • IF43_RS0103405
  • WP_030193540.1
  • upp
 263481 - 264116 (+) uracil phosphoribosyltransferase
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  • IF43_RS0103410
  • WP_037887244.1
 264121 - 264759 (-) LytR C-terminal domain-containing protein
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  • IF43_RS0103415
  • WP_003955420.1
 264864 - 265160 (-) type II toxin-antitoxin system VapB family antitoxin
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  • IF43_RS0103420
  • WP_030193546.1
 265249 - 266880 (+) DUF853 family protein
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  • IF43_RS0103425
  • WP_030193548.1
  • opcA
 266893 - 267816 (-) glucose-6-phosphate dehydrogenase assembly protein OpcA
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  • IF43_RS0103430
 268013 - 268594 (-) Fe-S cluster assembly protein HesB
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  • IF43_RS0103435
  • WP_030193551.1
 268716 - 269513 (+) VOC family protein
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  • IF43_RS38895
 269620 - >269872 (-) helix-turn-helix domain-containing protein
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  • IF43_RS0103445
  • WP_030193552.1
 270109 - 270531 (-) PIN domain nuclease
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  • IF43_RS0103450
  • WP_030193554.1
 270528 - 270743 (-) type II toxin-antitoxin system VapB family antitoxin
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  • IF43_RS0103455
  • WP_030193556.1
 270838 - 273264 (-) helicase-associated domain-containing protein
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  • IF43_RS0103460
  • WP_234331921.1
 273588 - 274424 (-) hypothetical protein
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  • IF43_RS0103465
  • WP_234331933.1
 274571 - 275266 (-) C1 family peptidase
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  • IF43_RS0103470
  • WP_051794609.1
 275398 - 276276 (-) phytanoyl-CoA dioxygenase family protein
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  • IF43_RS0103475
  • WP_030193564.1
 276276 - 276965 (-) TfuA-like protein
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  • IF43_RS0103480
  • WP_030193566.1
 276980 - 278332 (-) YcaO-like family protein
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  • IF43_RS0103485
  • WP_234331922.1
 278370 - 279587 (-) 50S ribosomal protein L11 methyltransferase
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  • IF43_RS40350
  • WP_051794611.1
 279595 - 280200 (-) hypothetical protein
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  • IF43_RS40355
  • WP_107048384.1
 280197 - 281141 (-) phosphotransferase
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  • IF43_RS0103500
  • WP_030193573.1
 281138 - 282145 (-) T3SS effector HopA1 family protein
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  • IF43_RS0103505
  • WP_030193576.1
 282142 - 283140 (-) phosphotransferase
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  • IF43_RS0103510
  • WP_107048385.1
  • tvaA
 283317 - 283580 (-) thioviridamide family RiPP peptide
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  • IF43_RS0103520
  • WP_030193583.1
 284864 - 287137 (+) DNA polymerase III subunit gamma and tau
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  • IF43_RS0103525
  • WP_030193586.1
  • purD
 287198 - 288451 (+) phosphoribosylamine--glycine ligase
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  • IF43_RS0103530
  • WP_030193589.1
 288770 - 290512 (+) membrane protein
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  • IF43_RS0103535
  • WP_234331923.1
 290719 - 292278 (+) phosphoribosylamine--glycine ligase
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  • IF43_RS0103540
  • WP_030193595.1
 292377 - 293282 (+) phosphoribosylaminoimidazolesuccinocarboxamide synthase
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  • IF43_RS0103550
  • WP_030193597.1
 293538 - 294179 (-) response regulator transcription factor
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  • IF43_RS0103555
  • WP_030193600.1
 294235 - 295497 (-) histidine kinase
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  • IF43_RS0103560
  • WP_030193602.1
 295521 - 296327 (-) ABC transporter permease
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  • IF43_RS0103565
  • WP_030193605.1
 296324 - 297283 (-) ABC transporter ATP-binding protein
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  • IF43_RS0103580
  • WP_030193607.1
 297800 - 298117 (-) Lsr2 family protein
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  • IF43_RS0103585
  • WP_030193610.1
  • purS
 298451 - 298696 (+) phosphoribosylformylglycinamidine synthase subunit PurS
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  • IF43_RS0103590
  • WP_030193612.1
  • purQ
 298699 - 299379 (+) phosphoribosylformylglycinamidine synthase subunit PurQ
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  • IF43_RS0103595
  • WP_030193614.1
  • purL
 299376 - 301625 (+) phosphoribosylformylglycinamidine synthase subunit PurL
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  • IF43_RS0103600
  • WP_030193616.1
 301707 - 302498 (+) maleylpyruvate isomerase family mycothiol-dependent enzyme
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  • IF43_RS0103605
  • WP_051794613.1
 302546 - 303034 (+) META domain-containing protein
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Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Entry added
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