BGC0002726: 4-chloropinselin biosynthetic gene cluster from Bipolaris sorokiniana
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 73,894 nt. (total: 73,894 nt).
This entry is originally from NCBI GenBank MK523385.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
Tailoring
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002726
Short description 4-chloropinselin biosynthetic gene cluster from Bipolaris sorokiniana
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MK523385.1
1 - 73894
via
Compounds
  • 4-chloropinselin
  • pinselin
  • chloromonilinic acid B
  • chloromonilinic acid D
  • 4-hydroxyvertixanthone
Species Bipolaris sorokiniana [taxonomy]
References
Chemical products information
4-chloropinselin Evidence:
(no structure information available)
pinselin Evidence:
(no structure information available)
chloromonilinic acid B Evidence:
(no structure information available)
chloromonilinic acid D Evidence:
(no structure information available)
4-hydroxyvertixanthone Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QCF41192.1
 5052 - 6770 (+) CcxA
    copy AA seq
    copy Nt seq
    • QCF41193.1
    		 11061 - 15857 (-) CcxB
      copy AA seq
      copy Nt seq
      • QCF41194.1
      		 18621 - 20355 (+) CcxC
        copy AA seq
        copy Nt seq
        • QCF41195.1
        		 24542 - 25075 (-) CcxD
          copy AA seq
          copy Nt seq
          • QCF41196.1
          		 26051 - 27157 (-) CcxE
            copy AA seq
            copy Nt seq
            • QCF41197.1
            		 30111 - 31600 (+) CcxF
              copy AA seq
              copy Nt seq
              • QCF41198.1
              		 39286 - 40833 (-) CcxG
                copy AA seq
                copy Nt seq
                • QCF41199.1
                		 41938 - 43571 (-) CcxH
                  copy AA seq
                  copy Nt seq
                  • QCF41200.1
                  		 44508 - 46826 (-) CcxI
                    copy AA seq
                    copy Nt seq
                    • QCF41201.1
                    		 47465 - 53101 (-) CcxJ
                      copy AA seq
                      copy Nt seq
                      • QCF41202.1
                      		 53494 - 56278 (+) CcxK
                        copy AA seq
                        copy Nt seq
                        • QCF41203.1
                        		 56576 - 57946 (-) CcxL
                          copy AA seq
                          copy Nt seq
                          • QCF41204.1
                          		 58372 - 58851 (-) CcxM
                            copy AA seq
                            copy Nt seq
                            • QCF41205.1
                            		 59348 - 61466 (-) CcxN
                              copy AA seq
                              copy Nt seq
                              • QCF41206.1
                              		 62162 - 63115 (+) CcxO
                                copy AA seq
                                copy Nt seq
                                • QCF41207.1
                                		 63470 - 64252 (-) CcxP
                                  copy AA seq
                                  copy Nt seq
                                  • QCF41208.1
                                  		 64761 - 66578 (+) CcxQ
                                    copy AA seq
                                    copy Nt seq
                                    • QCF41209.1
                                    		 67145 - 67663 (-) CcxR
                                      copy AA seq
                                      copy Nt seq
                                      • QCF41210.1
                                      		 68004 - 69407 (+) CcxS
                                        copy AA seq
                                        copy Nt seq
                                        • QCF41211.1
                                        		 69548 - 71740 (-) CcxT
                                          copy AA seq
                                          copy Nt seq
                                          Biosynthesis information

                                          No biosynthesis information available for this record.

                                          Annotation changelog

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2024-07-23
                                          MIBiG v4 annotathon
                                          • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Entry added
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Tailoring functions
                                          Tailoring enzymes detected in this region
                                          Oxidoreductases: dehydrogenase oxygenase
                                          QCF41194.1: cytochrome P450
                                          smcogs
                                          SMCOG1034: cytochrome P450
                                          QCF41208.1: Biaryl bond formation, Reduction
                                          MITE
                                          MITE0000160Biaryl bond formation, Reduction (identity: 63.00%)
                                          smcogs
                                          SMCOG1001: short-chain dehydrogenase/reductase SDR
                                          Transferases: acylase halogenase methyltransferase
                                          QCF41200.1: conventional flavin-dependent halogenase
                                          halogenases
                                          conventional flavin-dependent halogenase
                                          smcogs
                                          SMCOG1119: halogenase
                                          QCF41201.1: malonyl CoA-acyl carrier protein transacylase
                                          smcogs
                                          SMCOG1021: malonyl CoA-acyl carrier protein transacylase
                                          QCF41205.1: O-methyltransferase
                                          smcogs
                                          SMCOG1042: O-methyltransferase
                                          QCF41206.1: methyltransferase
                                          smcogs
                                          SMCOG1089: methyltransferase
                                          Hydrolases: hydrolase
                                          QCF41202.1: Decarboxylation
                                          MITE
                                          MITE0000163Decarboxylation (identity: 67.80%)
                                          smcogs
                                          SMCOG1170: metallo-beta-lactamase family protein
                                          Lyases: hydrolase
                                          QCF41202.1: Decarboxylation
                                          MITE
                                          MITE0000163Decarboxylation (identity: 67.80%)
                                          smcogs
                                          SMCOG1170: metallo-beta-lactamase family protein
                                          Ligases: dehydrogenase
                                          QCF41208.1: Biaryl bond formation, Reduction
                                          MITE
                                          MITE0000160Biaryl bond formation, Reduction (identity: 63.00%)
                                          smcogs
                                          SMCOG1001: short-chain dehydrogenase/reductase SDR
                                          Similar known clusters from MIBiG 4.0
                                          Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                          Detailed help and explanations are available here.

                                          Click on reference genes to show details of similarities to genes within the current region.
                                          Double click on a reference drawing to reverse the display of the genes.

                                          Click on an accession to open that entry in the MIBiG database.


                                          Location:

                                          Identifier
                                          Identity
                                          Coverage
                                          Detailed domain annotation
                                          Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                          A domain glossary is available here, and an explanation of the visualisation is available here.
                                          Selected features only
                                          Show module domains