BGC0002754: hectoramide B biosynthetic gene cluster from Moorena producens JHB
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Location: 3,909,117 - 3,972,303 nt. (total: 63,187 nt).
This entry is originally from NCBI GenBank CP017708.2, but has been modified (see Modifications tab for details).

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core biosynthetic genes
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General
Compounds
Genes
Biosynthesis
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KnownClusterBlast
NRPS/PKS domains
Modifications
General information about the BGC
MIBiG accession BGC0002754
Short description hectoramide B biosynthetic gene cluster from Moorena producens JHB
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP017708.2
3909711 - 3971211
via Correlation of genomic and metabolomic data, Homology-based prediction
Compounds
  • hectoramide B
Species Moorena producens JHB [taxonomy]
References
Chemical products information
hectoramide B Evidence: MS/MS, NMR
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C34H50N4O7
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BJP36_15380
  • AOY81076.1
 3909711 - 3910598 (+) hypothetical protein
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    • BJP36_15385
    • AOY84701.2
    		 3910595 - 3910993 (-) ATP-binding protein
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      • BJP36_15390
      • AOY84702.1
      		 3911457 - 3912446 (-) sugar transferase
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        • BJP36_15395
        • AOY81077.1
        		 3912562 - 3913341 (+) 7-carboxy-7-deazaguanine synthase QueE
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          • BJP36_39100
          • WAN70074.1
          		 3913379 - 3913630 (-) hypothetical protein
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            • BJP36_15405
            • AOY81079.1
            		 3913703 - 3914350 (-) DUF3318 domain-containing protein
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              • BJP36_15410
              • AOY81080.2
              		 3915036 - 3921809 (+) translocation/assembly module TamB domain-containing protein
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                • BJP36_15415
                • AOY81081.1
                		 3922048 - 3922347 (-) hypothetical protein
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                  • BJP36_39105
                  • WAN70075.1
                  		 3922350 - 3922502 (-) hypothetical protein
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                    • BJP36_39110
                    • WAN70076.1
                    		 3922749 - 3923063 (+) hypothetical protein
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                      • BJP36_39115
                      		 3923270 - 3923576 (-) hypothetical protein
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                        • BJP36_15430
                        • AOY84703.2
                        		 3923983 - 3924807 (+) hypothetical protein
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                          • BJP36_15435
                          • AOY81084.2
                          		 3924912 - 3927098 (+) tetratricopeptide repeat protein
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                            • BJP36_39120
                            		 3927601 - 3927819 (-) IS701 family transposase
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                              • BJP36_15445
                              • AOY81086.2
                              		 3928692 - 3928910 (+) beta-ketoacyl synthase N-terminal-like domain-containing protein
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                                • BJP36_15450
                                • AOY81087.1
                                		 3929117 - 3934792 (+) non-ribosomal peptide synthetase
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                                  • BJP36_15455
                                  • AOY81088.1
                                  		 3934795 - 3941742 (+) SDR family NAD(P)-dependent oxidoreductase
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                                    • BJP36_39125
                                    • WAN70077.1
                                    		 3941739 - 3946430 (+) amino acid adenylation domain-containing protein
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                                      • BJP36_39130
                                      • WAN70078.1
                                      		 3946427 - 3952303 (+) amino acid adenylation domain-containing protein
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                                        • BJP36_17830
                                        • AOY81497.1
                                        		 3952861 - 3953250 (+) hypothetical protein
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                                          • BJP36_17825
                                          • AOY81496.1
                                          • proX
                                          		 3953414 - 3954454 (+) glycine betaine/L-proline ABC transporter substrate-binding protein ProX
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                                            • BJP36_17820
                                            • AOY81495.1
                                            • proB
                                            		 3954580 - 3955695 (-) glutamate 5-kinase
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                                              • BJP36_17815
                                              • AOY81494.1
                                              		 3956226 - 3957134 (+) MBL fold metallo-hydrolase
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                                                • BJP36_39135
                                                • WAN70079.1
                                                		 3957084 - 3957266 (-) hypothetical protein
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                                                  • BJP36_17810
                                                  • AOY81493.2
                                                  		 3957686 - 3958516 (-) hypothetical protein
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                                                    • BJP36_39140
                                                    • WAN70080.1
                                                    		 3959108 - 3959278 (+) hypothetical protein
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                                                      • BJP36_17805
                                                      • AOY81492.1
                                                      		 3959667 - 3961007 (+) ABC transporter substrate-binding protein
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                                                        • BJP36_17800
                                                        • AOY81491.1
                                                        		 3961652 - 3962533 (+) sugar ABC transporter permease
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                                                          • BJP36_17795
                                                          • AOY81490.1
                                                          		 3962533 - 3963411 (+) carbohydrate ABC transporter permease
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                                                            • BJP36_17790
                                                            • AOY81489.2
                                                            		 3963385 - 3963753 (-) hypothetical protein
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                                                              • BJP36_17785
                                                              • AOY81488.2
                                                              		 3963756 - 3964106 (+) four helix bundle protein
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                                                                • BJP36_17780
                                                                • AOY81487.1
                                                                		 3964481 - 3965665 (+) ABC transporter ATP-binding protein
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                                                                  • BJP36_17775
                                                                  • AOY81486.1
                                                                  		 3966056 - 3967264 (+) hypothetical protein
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                                                                    • BJP36_17770
                                                                    • AOY84739.2
                                                                    		 3967386 - 3968852 (+) hypothetical protein
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                                                                      • BJP36_39145
                                                                      • WAN70081.1
                                                                      		 3968930 - 3969058 (+) hypothetical protein
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                                                                        • BJP36_17765
                                                                        • AOY81485.1
                                                                        		 3969055 - 3969834 (+) hypothetical protein
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                                                                          • BJP36_39150
                                                                          • WAN70082.1
                                                                          		 3969861 - 3970016 (-) hypothetical protein
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                                                                            • BJP36_39155
                                                                            • WAN70083.1
                                                                            		 3970004 - 3970258 (+) hypothetical protein
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                                                                              • BJP36_17760
                                                                              • AOY81484.1
                                                                              		 3970150 - 3971211 (-) catalase family protein
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                                                                                Biosynthesis information

                                                                                No biosynthesis information available for this record.

                                                                                Annotation changelog

                                                                                Entry version: 1

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2023-11-14
                                                                                Add new entry for hectoramide B
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                2023-11-14
                                                                                Reviewed and approved.
                                                                                • (ID: 55JKZ6YQD2AUFWZ45WR2BXVC)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                2023-11-21
                                                                                Reviewed and approved.
                                                                                • (ID: C62OJVVH7XOTOTFZSJT727YU)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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                                                                                Modifications to original record
                                                                                • BJP36_32295 crossed the origin and was split into two features