LOCUS       BGC0000012             21971 bp    DNA     linear   PLN 07-JAN-2006
DEFINITION  Alternaria solani alt1, alt2, alt3, alt4, alt5 genes for cytochrome
            P-450, cytochrome, P-450, cytochrome P-450, FAD/FMN-dependent
            oxygenase/oxidase, polyketide synthase, complete cds.
ACCESSION   BGC0000012
VERSION     BGC0000012
KEYWORDS    .
SOURCE      Alternaria solani
  ORGANISM  Alternaria solani
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
            Pleosporaceae; Alternaria; Alternaria sect. Porri.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 12:32:57
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..21971
                     /db_xref="taxon:48100"
                     /mol_type="genomic DNA"
                     /organism="Alternaria solani"
                     /strain="584"
     protocluster    1..21971
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[11260:19092]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11261..19092
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..21971
                     /SMILES="C([*])C(-O)(C)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..21971
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000012"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..21971
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(join(1893..2076,2126..2276,2339..2589,
                     2653..3527,3583..3696))
                     /gene="alt1"
     CDS             complement(join(1893..2076,2126..2276,2339..2589,
                     2653..3527,3583..3696))
                     /codon_start=1
                     /gene="alt1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 274; E-value: 3.9e-83)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /product="cytochrome P-450"
                     /protein_id="BAD83680.1"
                     /sec_met_domain="p450 (E-value: 4.4e-49, bitscore: 155.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAASELERRTKRSKSRNKISKPIANMLSVIAFSICISPIVYFLI
                     RSIYYLVFHPLSDYPGPKLWAISRIPWNYVNLQGDLAWRIRDMHLHYNSSVIRIAPDEL
                     SYTSSTALKKIDGTPPPREFLKCLDGRGIAPAVVNRRRSIVTETPERHTILRRALQPAF
                     SERALRDQEDFFRDHTDRLIAQLRKPQYGVTEQNILRWFALLSFDIMSDLAFGQPAGCL
                     DLVDEPWLGVIGSRVKSIVWYQFAVYYRIEWILKWIMPKAAMEARKRHQALTLQKVQRR
                     IEEERSGKREGKKRDFMSYILGNDKENLSNMDLFGMASAFIVAGSNTTTYTMTAFTFFV
                     CRDSEVYAKVIAEVRDKFASDTDITMVAAGDLPYLKACIEETMRLSPPTPSALPRWVLE
                     GGEEIDGKWVPGGVTVGVHNLAACHVPWNWHRPLEFIPERWLQTKEGEFTHDDRALHAR
                     FLMVDIMSLTCFLSSMAMNEMRLALAKLFWNFDISLSRNSGNWWITQKSYLVWEKKPLM
                     VTIKPRH"
     gene            complement(4088..5701)
                     /gene="alt2"
     CDS             complement(4088..5701)
                     /codon_start=1
                     /gene="alt2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 276.2; E-value: 8.5e-84)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /product="cytochrome P-450"
                     /protein_id="BAD83681.1"
                     /sec_met_domain="p450 (E-value: 2.1e-58, bitscore: 186.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTHLLILAAVVLLIIHIVNNFLIKPLQTLLKSRRLGCGPVPFEP
                     TRWPLDIDTIRRSLKADKEQRTPDFVAGRFETMGRYTWGLSLLGTSNLITAEPRNVQAL
                     LATQFDDFIMGTARRTNLKTALGRSIFAVDGKAWHRARETMRPIFSRENVSRLELLEEH
                     VQTMLQIIETKDEGLTTDANDRAWSAPVSLAVLLPRLTMDSATELFLGQSTHSLKKALA
                     RQQQKSGNEEHDADSFDHAFERMLAILGTRMRLRSLYWLYGNKELQKCINALHAFVDSA
                     IDAADQARKSGSSQLRYDFLETLRTRCSDRAEVREQVLGLLAAGRDTTASLTAWVFYCL
                     VRNPRVYKKLRDTVLAEFGPYSTNPGQKITFEKLKGCTYLQHVLNETLRLHSVVPFNSR
                     CAARDTTLPVGGGPDGSMPVFVPKGTEVNFSTHVLHRRKDLWGEDADEFVPERWEKKRP
                     GMTWQYVPFNGGPRICIGQQFALTEAGYVLVRMVQRYDVIEGLDIDVERDWHNFTVVCS
                     PGSPVARDAAVMCRLRVAVE"
     gene            complement(join(6091..7141,7207..7589,7645..7740))
                     /gene="alt3"
     CDS             complement(join(6091..7141,7207..7589,7645..7740))
                     /codon_start=1
                     /gene="alt3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 380.5; E-value: 2e-115)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /product="cytochrome P-450"
                     /protein_id="BAD83682.1"
                     /sec_met_domain="p450 (E-value: 8.4e-70, bitscore: 224.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALSSALDSLWHQLDQLLSLINRNIITGIIVLPVLYVLLKVIYNL
                     YLSPLAGYPGPKLWAVSRLPWNRANMKGRISWKIRELHDKYGPVVRIAPDELSYTTSGA
                     WKKIYGQRNPEFVKALDGRGIAPASIGGQRSLMTEHQDKHLRLRRAIDPAFSQRALREQ
                     ESYFQDHSDNLVQKLKQRCKDGPLDMTTWYNLVAFDIVSDLAFGEPSGCVNNPDQPWIQ
                     AILARAKAIVWFQLAVQYGFMGLLNWMTPKYVTESRKKHIAMTEAKLKARVEAKNPGKD
                     FMSYILENDEKLNHLELVMLSSNFIVAGSGTSAGGMSGLTYLLLRNPDKLEKLKQEIRG
                     LFKSRADMTLQAVTSCKYLRACLNEGMRLYPPTPGSLPRFVPGKGEMIEGKWVPGGYAV
                     GVNQLAAGHSERNFKKAREFHPERWLDEPDSEFKDDDRSAVQPFSYGQRGCIGRSMAYA
                     EMSLTMAKLVWYFDWELDEPDNDWWNQQGTYLVWEKLPLQVKLTPVSDVVE"
     gene            join(8580..9012,9102..9451,9499..9896,9954..10221)
                     /gene="alt4"
     CDS             join(8580..9012,9102..9451,9499..9896,9954..10221)
                     /codon_start=1
                     /gene="alt4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 295.9;
                     E-value: 1.4e-89)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /product="FAD/FMN-dependent oxygenase/oxidase"
                     /protein_id="BAD83683.1"
                     /transl_table=11
                     /translation="MDIQQGGNDLISLAATIRTELQQKLSSKARIHLPFDEDRTEFDKA
                     NLRFTQYERPTYLAIVDPVCEDDVIEAVKYARGKGIPFTPRGGHHSVTTTMGRFQNGIC
                     INMRPLNQMRWYAEKRHVTIGGGAITDEFVRFVHDLGMEVTFGAGLGRLQGKYGFLNDN
                     MVSCKLVLADGSTVIASKDSHPDLFWALRGAGHNFGIALEATFQVYPQAHGGIHHTWDL
                     EYTLDQCDEVFRTLNSVYESMPAELAIFILWLRQSSGRKHIILVNLVWSGPAAGADPYV
                     QRFESLQPVLNSGRKSVPWPELPFSTYKEINKLFCNPEIWLRGPYKMMGAACVERFDLK
                     TTREFFESVKSLSEEWEDRGWFSAMFECLPDQRVREISDDATAFPWRAGSNHFLMLNAT
                     PKRMEDRKVFEDHLNYWKRRFIETSGYGRLQQYVSYGNGTSTMKDPPEALYGYEPWRLE
                     KLRNLKQKYDPDNVFRWYQPLLEP"
     gene            join(11261..11445,11506..12064,12131..12516,12567..19092)
                     /gene="alt5"
     CDS             join(11261..11445,11506..12064,12131..12516,12567..19092)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (4-427). E-value:
                     2.5e-171. Score: 562.1. Matches aSDomain:
                     nrpspksdomains_alt5_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (582-892). E-value: 1.6e-94.
                     Score: 308.5. Matches aSDomain:
                     nrpspksdomains_alt5_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (966-1148). E-value: 2.7e-24.
                     Score: 78.3. Matches aSDomain:
                     nrpspksdomains_alt5_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1447-1621). E-value: 4.5e-76.
                     Score: 247.6. Matches aSDomain: nrpspksdomains_alt5_cMT.1"
                     /NRPS_PKS="Domain: PKS_ER (1852-2166). E-value: 3.4e-120.
                     Score: 392.7. Matches aSDomain:
                     nrpspksdomains_alt5_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2189-2365). E-value: 2.8e-49.
                     Score: 159.4. Matches aSDomain:
                     nrpspksdomains_alt5_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2465-2543). E-value: 7.9e-16.
                     Score: 50.1. Matches aSDomain:
                     nrpspksdomains_alt5_PKS_PP.1"
                     /codon_start=1
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /gene="alt5"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 253.1; E-value:
                     8.2e-77)"
                     /gene_kind="biosynthetic"
                     /product="PKSN polyketide synthase for alternapyrone
                     biosynthesis"
                     /protein_id="BAD83684.1"
                     /sec_met_domain="itr_KS (E-value: 1.3e-174, bitscore:
                     569.3, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.4e-95, bitscore: 308.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 5e-09, bitscore: 24.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.9e-16, bitscore:
                     47.8, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6.3e-41, bitscore:
                     128.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-09, bitscore:
                     26.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKPVAIIGIAFRGPGDARDPEAFYRMLVEGRNARTEIPKDRYNV
                     DAFYHPDSERLGSIQQRHAHFLQQDFKVFDAPFFSITPKEAKAMDPTHRILLEATYEGF
                     ENAGLSLEKVSGTQTSCYIGTFTADFPNLQARDNEGPSIYHATGMSASLASNRLSWFYN
                     LRGPSLTVDTACSSSLTAFHLACQSIRTGEAEMSVVGGANLMFGPDMSILLGAAKILSP
                     EGKSKMWDANANGFARGEGFGVTILKPLDAALRDGDNIRAVVLATAANEDGHTPGISLP
                     NSEAQQELIRRAYQIAGVDPAETAYVEAHGTGTQAGDPLEARAILKTIGSVEGRKSDLY
                     VGSVKTNIGHLEGAAGVAGIIKAALTVERGMIPPNLWFEKLNPEIDLPDNVKIASKLTP
                     WPHSGPRRASINSFGFGGANAHAILEDAASFLSRHGLSGRHTTAPLLPSLSSVRVSHPS
                     DSPSSSASTVAEEATSGESSDNISDVSSEVLRDVYPIPKLFVLSSHDQEGVKRSAERLQ
                     EYLASKTSTTPSFLNDLAYTLSAKRTTLPWKSYAVSSSVSGLREKISSLPPVVRSSTSA
                     IPRIAFVFTGQGAQWHAMGRGLSVYKTFAESLQRSEVMLKSFGCPWSLAEELSRSKAEY
                     KLRETDYSQPACTAIQVALVDLLSGFDVRPVAVLGHSSGEIAAAYAAGFIDQEAAIKIA
                     WLRGQVNKTVSKNGGMLAVSASADSIQSHLDGLKSGKAVVGCFNSTKACTVTGDTSAID
                     ELQTMLKDAQVACTRLPMDVAYHSFHMEAAREKYEQALEGIAHGSTSTIPMFSSVTGTL
                     VDPAQMKPSYWVDNLVSPVNFVAATRSLLSHPQESKSRKAFANLFVELGPHSALRSYLL
                     DIISSENRAADTTYTTLLRRNFDGAATALEAMGHLWAHGCKVDLSKVNDVSSDSTNMLI
                     DLPPYAWNHKPYWDESHLSRQHRLRKSPRTDLVGYRLLGTPEHTWRNFLRCNENPWIRE
                     HKVQGDILYPGAGMLVMAIEAAHQLAQETSADEIYGFELRDVSIDTALRVPDTEKGIEV
                     MTQLHNRRTGTRAAPSSTLYEFTVSSWSEEMSSWSTHARGLVSITFKTFSPSMEREVAL
                     GNERYMSSLAEVRRVCQTPARSFLYDTVETIGMQYGPTFRNMTELYAGPNSSYGVINVP
                     DTKAIMPKGFEFPHVVHPATLDSVLHLIFPSISGEDQALNEAVVPRSFDRIFVSASIPK
                     NAGAELRGCSSAKKLSYTTWNSNITMSDATMTEPVVIMEGVVLASVGATEDASKQLETR
                     ASCFAQNWHVDADLLTPSQIKEIIYKRTLKSKDDDSVLDLLEFVCLVYIYRILDWFQTE
                     EGKPHVPRDGFWKSYVEWMHDTVKQFPALPADVETEMEKARQRIVKSESGDITVQMVDR
                     IGQNLSRIFTREVEALQCMTEGDLLYSFYRGAFGTSFNTNVAEYVGLIADKQPGLRILE
                     IGAGTGGTTYHVLERLRNPDGTSKAAQYYFTDISPGFLAKAADRFNQDASIMQFGTLNI
                     ENAPTEQGFSPELFDLIVCANVLHATKSIQETLTHCKLLLKPGGRLVLSEVTIKRIFSG
                     FIMGPLPGWWLGEADGRMGGPLLDADEWNVALKKAGFSGVDVDVRGDRETSKEPVSLLI
                     STKPKTTAPSLPSCLVITTGTEASNMLADTIQRVFTSAGHDISIAQWNSVTKTQVEGKY
                     CLCLAEWEDAILVNLTDDDWDRLREVVLSSEGALWITGGGALDTPFPMKSLMVGLGRAI
                     RNEDAGVRLACLDLDPPTTIDFEEASRTTLKVAYAHIRGDGTEGEFAAHGDKVYVPRVE
                     RTLQVDGSLRKYEAKGDPEMVPFKSCGRPLKLTIKTPGLLDTFQWEEDETYHTPLPEDW
                     IEIEVKAVGLNFKDVLVALGNLAENKLGVDASGIVTRVGSAVTNVQVGDRVMTASCDTF
                     ATYVRFPAKGAIGVPTGMSFEEAASMPLIFLTAYYALVTAGGIVAGEKVLIHAAAGGVG
                     QAAIMIAQAKGAEIFATVGADTKKQLLIEQYGIPEDHIFSSRDTSFVKGVLRATDGQGV
                     DLVLNSLAGEALRLSWTDCLAKFGRFLEIGKADLFANTGLDMKPLLDNKSYIGVNLLDF
                     ENNPTPRAVALWHDTAKMIHDGAIKPIAPLQVFTMAEVEKAFRHMQAGKHMGKVVVRVD
                     DADVVRAVPRIPRVSIHPDATYMIAGLGGITREIARWLAEKGARYLVFLSRSAASGTDN
                     QAFALQLRNTYDVTPLAYDCDVGNKAALQAVLDDLKAKGLPPINGCATGAMVLQDCLFD
                     KMTADHVRTTVGPKVHGTWNLHELLPRDMDFFVMLSSLAGVMGHRGQGNYGCGNNFQDE
                     FASFRRGQGLPAMTIDIGYLLSVGFVAEHDEYVDHVKAMGLKVMHTSDLHGLVATAIEG
                     PSQHPGQVMCGLPFNEHDDAWYWMADARFAALRNVAAGSAANAGQAISLREELTRCGTV
                     NEEAVQLITAAIAQRLASLMMIPEADIDAGRPLSAYGVDSLVAVEVRNWVAREMAVEVS
                     VFDVMQNVPMTQLAQNLAEKSKLLLGQA"
     aSDomain        join(11273..11445,11506..12064,12131..12516,12567..12717)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_alt5_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.50E-171"
                     /label="alt5_PKS_KS.1"
                     /locus_tag="alt5"
                     /protein_end="427"
                     /protein_start="4"
                     /score="562.1"
                     /tool="antismash"
                     /translation="VAIIGIAFRGPGDARDPEAFYRMLVEGRNARTEIPKDRYNVDAFY
                     HPDSERLGSIQQRHAHFLQQDFKVFDAPFFSITPKEAKAMDPTHRILLEATYEGFENAG
                     LSLEKVSGTQTSCYIGTFTADFPNLQARDNEGPSIYHATGMSASLASNRLSWFYNLRGP
                     SLTVDTACSSSLTAFHLACQSIRTGEAEMSVVGGANLMFGPDMSILLGAAKILSPEGKS
                     KMWDANANGFARGEGFGVTILKPLDAALRDGDNIRAVVLATAANEDGHTPGISLPNSEA
                     QQELIRRAYQIAGVDPAETAYVEAHGTGTQAGDPLEARAILKTIGSVEGRKSDLYVGSV
                     KTNIGHLEGAAGVAGIIKAALTVERGMIPPNLWFEKLNPEIDLPDNVKIASKLTPWPHS
                     GPRRASINSFGFGGANAHAILEDA"
     aSModule        11273..19065
                     /complete
                     /domains="nrpspksdomains_alt5_PKS_KS.1"
                     /domains="nrpspksdomains_alt5_PKS_AT.1"
                     /domains="nrpspksdomains_alt5_PKS_DH.1"
                     /domains="nrpspksdomains_alt5_cMT.1"
                     /domains="nrpspksdomains_alt5_PKS_ER.1"
                     /domains="nrpspksdomains_alt5_PKS_KR.1"
                     /domains="nrpspksdomains_alt5_PKS_PP.1"
                     /iterative
                     /locus_tags="alt5"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       11738..11782
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0001"
                     /evalue="1.90E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="alt5"
                     /protein_end="154"
                     /protein_start="139"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="GPSIYHATGMSASLA"
     CDS_motif       11816..11863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0002"
                     /evalue="1.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="alt5"
                     /protein_end="181"
                     /protein_start="165"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GPSLTVDTACSSSLTA"
     CDS_motif       12005..12043
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0003"
                     /evalue="3.20E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="alt5"
                     /protein_end="241"
                     /protein_start="228"
                     /score="10.8"
                     /tool="antismash"
                     /translation="WDANANGFARGEG"
     CDS_motif       12302..12349
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0004"
                     /evalue="2.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="alt5"
                     /protein_end="321"
                     /protein_start="305"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YVEAHGTGTQAGDPLE"
     CDS_motif       12410..12454
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0005"
                     /evalue="9.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="alt5"
                     /protein_end="356"
                     /protein_start="341"
                     /score="11.7"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEGAAG"
     CDS_motif       13180..13230
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0006"
                     /evalue="7.90E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="alt5"
                     /protein_end="598"
                     /protein_start="581"
                     /score="18.2"
                     /tool="antismash"
                     /translation="FVFTGQGAQWHAMGRGL"
     aSDomain        13183..14112
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_alt5_PKS_AT.1"
                     /evalue="1.60E-94"
                     /label="alt5_PKS_AT.1"
                     /locus_tag="alt5"
                     /protein_end="892"
                     /protein_start="582"
                     /score="308.5"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWHAMGRGLSVYKTFAESLQRSEVMLKSFGCPWSLAEE
                     LSRSKAEYKLRETDYSQPACTAIQVALVDLLSGFDVRPVAVLGHSSGEIAAAYAAGFID
                     QEAAIKIAWLRGQVNKTVSKNGGMLAVSASADSIQSHLDGLKSGKAVVGCFNSTKACTV
                     TGDTSAIDELQTMLKDAQVACTRLPMDVAYHSFHMEAAREKYEQALEGIAHGSTSTIPM
                     FSSVTGTLVDPAQMKPSYWVDNLVSPVNFVAATRSLLSHPQESKSRKAFANLFVELGPH
                     SALRSYLLDIISSENRAADTTYTTLLRRN"
     CDS_motif       13423..13533
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0007"
                     /evalue="1.10E-10"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="alt5"
                     /protein_end="699"
                     /protein_start="662"
                     /score="33.5"
                     /tool="antismash"
                     /translation="VRPVAVLGHSSGEIAAAYAAGFIDQEAAIKIAWLRGQ"
     CDS_motif       13891..13935
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0008"
                     /evalue="2.90E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="alt5"
                     /protein_end="833"
                     /protein_start="818"
                     /score="10.4"
                     /tool="antismash"
                     /translation="KPSYWVDNLVSPVNF"
     aSDomain        14335..14880
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_alt5_PKS_DH.1"
                     /evalue="2.70E-24"
                     /label="alt5_PKS_DH.1"
                     /locus_tag="alt5"
                     /protein_end="1148"
                     /protein_start="966"
                     /score="78.3"
                     /tool="antismash"
                     /translation="LLGTPEHTWRNFLRCNENPWIREHKVQGDILYPGAGMLVMAIEAA
                     HQLAQETSADEIYGFELRDVSIDTALRVPDTEKGIEVMTQLHNRRTGTRAAPSSTLYEF
                     TVSSWSEEMSSWSTHARGLVSITFKTFSPSMEREVALGNERYMSSLAEVRRVCQTPARS
                     FLYDTVETIGMQYGPTFRN"
     CDS_motif       14392..14469
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0009"
                     /evalue="5.30E-12"
                     /label="PKSI-DH_m2"
                     /locus_tag="alt5"
                     /protein_end="1011"
                     /protein_start="985"
                     /score="38.1"
                     /tool="antismash"
                     /translation="WIREHKVQGDILYPGAGMLVMAIEAA"
     aSDomain        15778..16299
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_alt5_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="4.50E-76"
                     /label="alt5_cMT.1"
                     /locus_tag="alt5"
                     /protein_end="1621"
                     /protein_start="1447"
                     /score="247.6"
                     /tool="antismash"
                     /translation="GLIADKQPGLRILEIGAGTGGTTYHVLERLRNPDGTSKAAQYYFT
                     DISPGFLAKAADRFNQDASIMQFGTLNIENAPTEQGFSPELFDLIVCANVLHATKSIQE
                     TLTHCKLLLKPGGRLVLSEVTIKRIFSGFIMGPLPGWWLGEADGRMGGPLLDADEWNVA
                     LKKAGFSGVDV"
     aSDomain        16993..17934
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_alt5_PKS_ER.1"
                     /evalue="3.40E-120"
                     /label="alt5_PKS_ER.1"
                     /locus_tag="alt5"
                     /protein_end="2166"
                     /protein_start="1852"
                     /score="392.7"
                     /tool="antismash"
                     /translation="GLLDTFQWEEDETYHTPLPEDWIEIEVKAVGLNFKDVLVALGNLA
                     ENKLGVDASGIVTRVGSAVTNVQVGDRVMTASCDTFATYVRFPAKGAIGVPTGMSFEEA
                     ASMPLIFLTAYYALVTAGGIVAGEKVLIHAAAGGVGQAAIMIAQAKGAEIFATVGADTK
                     KQLLIEQYGIPEDHIFSSRDTSFVKGVLRATDGQGVDLVLNSLAGEALRLSWTDCLAKF
                     GRFLEIGKADLFANTGLDMKPLLDNKSYIGVNLLDFENNPTPRAVALWHDTAKMIHDGA
                     IKPIAPLQVFTMAEVEKAFRHMQAGKHMGKVVV"
     CDS_motif       17083..17118
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0010"
                     /evalue="5.90E-04"
                     /label="PKSI-ER_m1"
                     /locus_tag="alt5"
                     /protein_end="1894"
                     /protein_start="1882"
                     /score="12.8"
                     /tool="antismash"
                     /translation="GLNFKDVLVALG"
     CDS_motif       17137..17175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0011"
                     /evalue="1.70E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="alt5"
                     /protein_end="1913"
                     /protein_start="1900"
                     /score="11.4"
                     /tool="antismash"
                     /translation="LGVDASGIVTRVG"
     CDS_motif       17302..17346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0012"
                     /evalue="5.40E-05"
                     /label="PKSI-ER_m4"
                     /locus_tag="alt5"
                     /protein_end="1970"
                     /protein_start="1955"
                     /score="16.5"
                     /tool="antismash"
                     /translation="AASMPLIFLTAYYAL"
     CDS_motif       17371..17433
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0013"
                     /evalue="1.20E-10"
                     /label="PKSI-ER_m5"
                     /locus_tag="alt5"
                     /protein_end="1999"
                     /protein_start="1978"
                     /score="33.5"
                     /tool="antismash"
                     /translation="GEKVLIHAAAGGVGQAAIMIA"
     CDS_motif       17443..17493
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0014"
                     /evalue="9.90E-06"
                     /label="PKSI-ER_m6"
                     /locus_tag="alt5"
                     /protein_end="2019"
                     /protein_start="2002"
                     /score="18.2"
                     /tool="antismash"
                     /translation="GAEIFATVGADTKKQLL"
     CDS_motif       17572..17610
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0015"
                     /evalue="1.70E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="alt5"
                     /protein_end="2058"
                     /protein_start="2045"
                     /score="14.2"
                     /tool="antismash"
                     /translation="TDGQGVDLVLNSL"
     CDS_motif       17887..17934
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0016"
                     /evalue="1.40E-07"
                     /label="PKSI-ER_m9"
                     /locus_tag="alt5"
                     /protein_end="2166"
                     /protein_start="2150"
                     /score="24.1"
                     /tool="antismash"
                     /translation="AFRHMQAGKHMGKVVV"
     CDS_motif       18004..18099
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0017"
                     /evalue="6.60E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="alt5"
                     /protein_end="2221"
                     /protein_start="2189"
                     /score="44.4"
                     /tool="antismash"
                     /translation="TYMIAGLGGITREIARWLAEKGARYLVFLSRS"
     aSDomain        18004..18531
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_alt5_PKS_KR.1"
                     /evalue="2.80E-49"
                     /label="alt5_PKS_KR.1"
                     /locus_tag="alt5"
                     /protein_end="2365"
                     /protein_start="2189"
                     /score="159.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TYMIAGLGGITREIARWLAEKGARYLVFLSRSAASGTDNQAFALQ
                     LRNTYDVTPLAYDCDVGNKAALQAVLDDLKAKGLPPINGCATGAMVLQDCLFDKMTADH
                     VRTTVGPKVHGTWNLHELLPRDMDFFVMLSSLAGVMGHRGQGNYGCGNNFQDEFASFRR
                     GQGLPAMTIDIGY"
     CDS_motif       18334..18363
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0018"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="alt5"
                     /protein_end="2309"
                     /protein_start="2299"
                     /score="12.2"
                     /tool="antismash"
                     /translation="PKVHGTWNLH"
     CDS_motif       18382..18492
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_alt5_0019"
                     /evalue="4.60E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="alt5"
                     /protein_end="2352"
                     /protein_start="2315"
                     /score="57.8"
                     /tool="antismash"
                     /translation="MDFFVMLSSLAGVMGHRGQGNYGCGNNFQDEFASFRR"
     aSDomain        18832..19065
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_alt5_PKS_PP.1"
                     /evalue="7.90E-16"
                     /label="alt5_PKS_PP.1"
                     /locus_tag="alt5"
                     /protein_end="2543"
                     /protein_start="2465"
                     /score="50.1"
                     /tool="antismash"
                     /translation="EEAVQLITAAIAQRLASLMMIPEADIDAGRPLSAYGVDSLVAVEV
                     RNWVAREMAVEVSVFDVMQNVPMTQLAQNLAEK"
ORIGIN
        1 ggaacatcat tcaccttcat gactccttcg tctatatgca acgttttctc aaatattgtt
       61 gccaccggcc gtaaagtgac agatgtttca gcgcatttcg cagctgcctg gaatgacaag
      121 ggactggtgc acgtatctct ctgaccgcct ttcacctatc gtcccatgct tgcattcacc
      181 aacgcatgcg cccttgacac agacttggtt ctaaattgaa atgaaaacag aaagcatcag
      241 aacaccatac atgcgttgtt cgatgcttca ttccagatgt aatgaggtcg ggccaagaga
      301 atcttcgcga tccttccact ttcgtacttt gccgatctgc cacctccctc accaacacga
      361 ccaatgacct ccgtcaccat gccttcgcca acgtctgctt cacagtactc aaggtcgctg
      421 cccattgcgc accagatctg cttctccagg caatcaagcc tatgattcca gcactcaagc
      481 catagggtat cgctttcttg gcaaacctca ccgcaacgtg cttgaagaac atattctgtt
      541 tctgcctcac ccgcttcacg tgctcccccc tcttgttctt tacggggaac ggcgtgtttg
      601 gtgtctcttt ccctaggaac tcacaaagtg gttcccatcc atcctccaag tgcagctcga
      661 gcaagcgctc cgccggcacc gcagctcgga cttctgcata gtgttgccta tatcggtcct
      721 tggcaacccg tcgcatatcc ttcacgttgc gcacgccgta gaaaccgagc ataattttgc
      781 gaatcgtctt gccgccgttg agtccataca gtggtcccaa cacgttgatg acgagatctg
      841 cgcgcaaccc ccacgtcgta ctgaagatgg cctcttccat gctgtcatac cactcgtcga
      901 tatcacgttc caccagaata accttcgcct cgggataggc ttcgattagc tgcgtcgcga
      961 agaaggagcc catatcggtg acggcttcgt aagggccaaa aagaacatcc cagtctgcgc
     1021 gtgtgaatgg ctcacccgtg taggtaggga gcacaggaaa gaaggcgtca caggccttgc
     1081 tgaatagctg ccactcaagt ggtgagctta gagcctggat gccatggtgt acaccttcat
     1141 atcccagtat ctcaagagct tgagttatcg aggccgatcc tatttcgtaa gttggcttcg
     1201 atcctttcaa gacgacaatg cacgacaaca ggatttcaga agtctgagaa actcaccggt
     1261 acgtgtcatt cctagtgaaa gcactttcag ctcgcgtttg ggacggtccg ccatggctca
     1321 gacagaattc ggtctaacta acgtagaaac gccaatgagt gtatatggac ggtagtgaga
     1381 tcagactgca ttccatcacc acccgaagat tggacaggac agttatcact gcatatctgc
     1441 tgttaaccat ggaccgtgat ccaaacatgt cttcgcaacg catctgccag aaccttgaac
     1501 acgtggtcaa gggagtggcc attttacttg cgctcgagtt ctatcgccga agagcgccga
     1561 cagccatcaa cacgatctac gcgtagaccc atttcaggtc tcaatacgtt cggtccgaac
     1621 tccaacgggc cgagcaaatt tcccctgcaa atgtatcgca aatgatcagc ccacgcccca
     1681 aacgtgcgac acatcgtgcg caaccatcgc ctagttttgg cagggtgttc tcgggcagaa
     1741 atattccgcg aagaaagtca caacatgtgg ggtagcgctg tcacacactt ctgctggcat
     1801 tctccgtttg agaaatagta gagtgagcta tcatgagatg ggcttttaca tgaacacagc
     1861 atacgctggc ctcagattct gacaatcgct aactaatgcc gtggctttat cgtgaccatg
     1921 agcggcttct tctcccacac caaatacgac ttttgtgtga tccaccaatt cccagagttg
     1981 cggctcaagg agatatcaaa attccagaac agcttggcca aggcaagcct catctcgttc
     2041 attgccatgc tggaaagaaa acatgttagc gacatactag tggtgagaga gggagcgggt
     2101 atgcttacgt ttgcccgata cagtcatgtc gaccataaga aaacgggcgt gaagcgcacg
     2161 gtcatcgtga gtgaactctc cctctttcgt ctgcagccac ctctcgggga tgaactcgag
     2221 aggccgatgc cagttccatg gaacatggca ggccgccagg ttgtgcacgc ctacggcagt
     2281 ctttgcgatt cgacttgtca gtaaatggtc tccacggcgc aaatagacaa gaaaggactt
     2341 actcctcccg gcacccattt accgtctatc tcttctccac cctccagaac ccagcgcggc
     2401 aaagctgaag gtgtaggagg tgacaagcgc atcgtctcct cgatgcaagc tttcaagtaa
     2461 ggtaggtcac cagcagcaac catggtgatg tcagtatcac tcgcgaattt gtctcgcacc
     2521 tcggcgatga ctttggcata aacctctgaa tctcgacaaa cgaagaaggt gaaagcagtc
     2581 atagtatacc taatgtcgat gtatcaagtc agtacaattt cacacggagt tcttgcaggg
     2641 acgttttctt acgtggtcgt gttgctgccc gccacaatga acgcactcgc catgccaaac
     2701 aagtccatgt tgctcagatt ttccttatca ttaccaagga tatagctcat gaaatctctc
     2761 ttctttccct ctcgttttcc gctacgctct tcttcaatcc gtcgctgcac cttctgcagc
     2821 gtcaaagcct ggtgccgctt ccgcgcctcc atggccgctt tgggcatgat ccatttcagg
     2881 atccattcga tgcggtagta cacggcaaac tggtaccaaa caatactctt gacgcgcgac
     2941 ccaatgactc cgagccaggg ctcatccaca agatctagac agccggccgg ctgaccaaag
     3001 gctagatcgc tcatgatatc gaaactgagc agggcaaacc agcggaggat gttctgctca
     3061 gtgacaccat actgtggctt tcgcagctgt gcgattagtc ggtctgtatg gtcgcggaag
     3121 aagtcttctt ggtcgcgcaa cgcacgctca ctgaaggcgg gctggagggc acgacggaga
     3181 atagtgtgcc gttcgggcgt ctcggtgaca atgctgcggc gcctgttaac aaccgcagga
     3241 gcgataccac ggccgtctag acatttgaga aactcgcgcg gcggtggagt gccgtctatc
     3301 ttcttcaggg ctgtgctgct tgtatacgac agctcatccg gagcaatacg tatcacgctg
     3361 ctgttgtagt gcagatgcat atcacgaata cgccatgcga ggtctccttg caggttgaca
     3421 tagttccagg gtatgcggga gatggcccag agcttgggac ctggataatc ggatagagga
     3481 tggaagacga ggtagtagat ggagcgaatg aggaagtaca cgatgggctg tgctcgatta
     3541 gacttttatt tctggctaac acttttagaa gtatcaacct acactgatgc agattgaaaa
     3601 agctataaca gacaacatgt tcgcgatggg cttggaaatc ttgtttctac tcttgctcct
     3661 cttggttcgt ctttcaagtt ctgaggccgc gggcatgtga tcgcgtgcta aggggagtgg
     3721 tgttgaacat gtttctctcc cacgaagtac aatgagccaa ttggaacaaa caggtatcca
     3781 cgtggttcat tcggttattc tgagcctctg gtattgaatg cagtcgtata tgcagtcttc
     3841 ggcttttacc agcccctggt caagccctcg gtggtacata catactggta ccctgaaccc
     3901 gtattcggcc cgcgtcaccg tttcctgaca taatgactcg cttcccgatg ttcataccgc
     3961 ggccgtatcg ataaaaacgg aaaagacaac agctgcacgt acattgcgtt ctgaactatc
     4021 tgtgtggaga acatggcgcg ataccggact tatacttgag gtagtaccga tgatgatacc
     4081 aacaaactca ctccacggcg accctcaatc ggcacatgac cgcagcatcc cttgccactg
     4141 gactgccagg gctacacacg acagtgaagt tatgccaatc gcgctccacg tcaatatcca
     4201 gaccctcgat gacatcatac ctctgcacca tccttaccag cacataccca gcctctgtaa
     4261 gtgcaaactg ctggccaata cagatgcgcg gtccaccatt gaaaggcacg tactgccacg
     4321 tcattcccgg tctcttcttc tcccaccgct caggcacaaa ctcgtcggcg tcttcgcccc
     4381 acaagtcttt ccgtcggtgc agcacatgcg tactgaagtt gacttcggtg cccttgggta
     4441 cgaatacagg catgcttcca tcgggtccac caccgacagg aagcgtcgtg tctcgtgcag
     4501 cgcagcggga gttgaacggg acgaccgagt gtaaccgtag tgtttcgttt agaacgtgtt
     4561 gtaggtaggt gcagcccttg agcttctcga atgttatctt ctgcccagga ttcgttgagt
     4621 aagggccaaa ctctgcaaga acagtgtcac gtagcttttt gtacactcgt gggtttctta
     4681 ctaggcagta gaagacccat gctgtaagtg acgccgtcgt atctctgccc gcggccagca
     4741 agcctagtac ttgctcgcgt acttcggcgc gatcggagca acgcgtacgc agtgtttcga
     4801 gaaagtcgta gcgtagttgt gatgaacctg actttcgtgc ttgatcagcg gcgtcgatgg
     4861 cgctgtctac gaaagcgtga agagcgttga tacacttttg gagttccttg ttgccgtaaa
     4921 gccagtatag gcttcgtagt cgcattcttg tccctaggat agcgagcatg cgctcgaagg
     4981 catgatcgaa actatccgca tcgtgttctt cattgccgct tttttgctgc tgtctggcaa
     5041 gcgccttctt gagagaatgt gtgctctgcc cgaggaacaa ttcggttgca gaatccatag
     5101 tcagacgcgg caacagtaca gccaagctca caggtgccga ccatgctctg tcattagcat
     5161 cagtcgtcaa cccctcgtct ttcgtctcga taatctgcaa catagtttgc acatgttcct
     5221 cgagtaactc gagccgggaa acattctctc ggctgaagat cggccgcatc gtttcccttg
     5281 cacgatgcca tgctttgcca tccacagcaa agatactgcg cccaagcgcc gtcttcaagt
     5341 ttgtcctcct cgcagtaccc atgatgaagt cgtcgaattg cgttgcgagg agtgcttgta
     5401 cgttgcgcgg ctcggctgtg ataagattcg atgtacccag cagcgataaa ccccaggtat
     5461 agcgacccat ggtttcaaag cggccagcta caaaatcagg agttctttgc tctttgtcgg
     5521 cttttaggct ccggcgtata gtgtcgatat cgagaggcca tcgggttggc tcaaatggca
     5581 ctgggccaca tccgagacgg cggctcttga ggagtgtttg caggggtttt attagaaaat
     5641 tgttgacaat gtgaataata agcagtacta ctgccgcgag gataagaagg tgtgtttgca
     5701 tcttgaatga tagcggatcg acgtgtcttg agctcgtact gctacctgga tgatacacca
     5761 ctggcaattt aaatatgcta acgagccctt cttgctaggg tagcatcttg agcccacgta
     5821 tagtgcacta gtcatgggat cggtgccctc tcaaagtcct ggtctgtgtg ttgaccaccg
     5881 catactggac cttcccagca aggaaggcta ggagtgttcg tcaaaatcac cactgcgact
     5941 ctaacggcgg atgcatgttg tcttgcgatc ttttatttga acccgtgtct agcaacattt
     6001 catctacttg tttggctact ggctatctgc atgactagcc agacatcaca tatatcgtaa
     6061 gcacttctac agctccttgc tctgctacca ttattcgacc acatcagaca caggcgtcag
     6121 cttgacctgc aaaggcaact tctcccatac caagtaggtg ccctgctgat tccaccagtc
     6181 gttgtcgggc tcatcgagct cccagtcaaa ataccatacc agcttcgcca ttgtgagaga
     6241 catctcggca taggccatag atcgtccaat acaacccctt tgaccatacg agaatggctg
     6301 gactgcagag cgatcgtcat ccttaaactc agagtcgggc tcatcgagcc agcgctcggg
     6361 atggaactcg cgtgccttct tgaagttacg ttcagagtga ccagcagcta actggttgac
     6421 accaacagca taaccccctg ggacccattt gccttcaatc atttcgcctt tgccaggaac
     6481 aaatcgtggc agcgaacccg gtgttggtgg atagaggcgc ataccctcgt tgagacaggc
     6541 gcgcaggtac ttgcagctgg tcactgcctg gagggtcata tccgcgcggc ttttgaacag
     6601 accgcgtatt tcttgcttga gtttctctag tttgtctggg ttgcgcaaga gaagatatgt
     6661 caagccggac atgccgcctg cagacgtgcc gctacccgcg acgatgaagt tggaagaaag
     6721 cattaccagt tcaaggtggt tgagcttctc gtcgttttct aggatgtatg acatgaagtc
     6781 cttgccgggg tttttggctt caactcgcgc cttcagcttg gcctcggtca tagcgatgtg
     6841 tttcttcctc gactcggtaa cgtattttgg tgtcatccag ttgagtagac ccataaaccc
     6901 gtattgtact gcaagctgaa accagacgat ggctttggcg cgagcgagga tagcttgaat
     6961 ccatggttgg tcaggattgt tgacacagcc tgacggctca ccgaaagcca aatccgatac
     7021 gatgtcgaat gcgacgagat tgtaccatgt agtcatatct agggggccgt ctttgcaccg
     7081 ttgcttcagc ttctggacaa gattgtccga gtggtcttgg aaatagctct cttgttcacg
     7141 tctagcatta tacagtcagc atggtcggat aaagcttcca aatcgagatg tagcggtcag
     7201 actcacagtg ctctctgact aaatgccgga tctatggccc tcctcagcct cagatgtttg
     7261 tcttggtgct cagtcatcag gcttcgttgg ccgccgatac tcgcaggcgc aatgcctctg
     7321 ccgtcaaggg ccttgacgaa ttcagggttt cgctgtccgt atatcttttt ccaagcgcca
     7381 gacgtcgtat acgagagttc gtctggggcg atacgcacaa cgggaccgta cttgtcgtgg
     7441 agctcgcgga tcttccagct gatgcgaccc ttcatatttg cgcgattcca tggtaggcga
     7501 gagacagccc agagctttgg acctgggtag ccagctaaag ggctgaggta aagattgtaa
     7561 atgactttga gcaagacata aagtacgggc tgcgcactgt tgtgagcttt cgaggaagcg
     7621 aaggcagagc ttgtgcgaac ttacgagcac aatgatacca gtgataatgt tgcgatttat
     7681 caacgatagt aattgatcga gctgatgcca caaactatcc agcgcggaag atagtgccat
     7741 ggtacctagg tgccgtgaaa ttgccagaat acagcggaat caacattcag agctccaagt
     7801 tccagagaaa agacggctca gtttccttca gcccagagtc caggcgacag ctcagagtgg
     7861 cagggaaatc taccgcggca tctctggata gtacgcgcct ttgttgaagc gctgcatttc
     7921 cctccttgtc ctctgacccc aggcttcgtg ctcaccgagc aatggtgccg agcagaagta
     7981 tccaatgaga cttcctcatc gttgcacgct ctgcaagaaa atgtgtatac gaagaatccc
     8041 caaggtattc cgaaagaaga cgcataggcc gatccaggtg acccgggctt ttattcggcc
     8101 ctagcaggtc gggccgatcc tctctccgag ataacatgca taacggcagc atgtcgtgcg
     8161 tgtacacttg tgggtaccgc tgtccacgtg ggtctaccca cggtaagcaa ataactacgt
     8221 gaagcttggc cacgtgctgt ggatatatgg cgaagcttga ccagaggttg agcggaaaaa
     8281 tgattcagag ttctgggcga cagtgcaggg taatgtggag ccagtctaca cctacatggg
     8341 tctagaagtg tgtcagttct tcttgcgtag cactcagcac gcgataatgt tcggccgtag
     8401 gtaccgatac gctgaaggtc ttcatcgact gcgacgaccc gttgctaata cgcctgtagc
     8461 tgagcagttt gttagatgca agaccttctg tttcgtctga tccttcttcc ataggccgtc
     8521 tttgcacaat catcaatcga tctagttagc atttcaaatc gtcagttcaa gtatagaaca
     8581 tggatatcca acaaggcggc aatgacctca tctcgctggc agccacaatt cgcaccgagc
     8641 tccagcaaaa gctgtcgagc aaggcacgaa tccatctgcc gttcgacgag gacagaaccg
     8701 agttcgacaa agccaatttg cgcttcactc agtatgagcg cccgacatac ctcgctattg
     8761 tcgatccagt ctgtgaagat gatgtgatcg aggctgtcaa gtatgcgcga ggaaaaggta
     8821 ttccgttcac acctcgtggc ggccatcatt cagtcacgac cacaatggga cgcttccaga
     8881 atggcatatg catcaatatg cgtccactca accagatgcg gtggtatgcc gagaaacgtc
     8941 atgtcaccat tggtggtgga gcgataactg acgagttcgt gcgctttgtg catgacttgg
     9001 gcatggaagt cagtatgtat gacatatcct tttgttacag tggcagtgtt aacgagacaa
     9061 agatgttgga tcgtgtccga ccaccggggt cattggtgta gcgtttggag cgggcctagg
     9121 acgtttacaa ggaaagtatg gcttcctcaa cgataacatg gtttcctgca aactcgtgct
     9181 cgccgacgga agtacggtga ttgcatccaa agattcgcac ccggatctgt tctgggctct
     9241 caggggagca ggccataact ttggtatcgc acttgaagcc acgttccagg tctatccgca
     9301 agcacatggg ggtatacacc atacttggga cttggagtac actctagatc agtgtgatga
     9361 ggtattcagg accttgaata gcgtttatga gagtatgcct gccgaactgg caatcttcat
     9421 cttatggctg cgccagagta gtggtcgcaa ggtaggtcct tccgtaacga gagtagtgac
     9481 gccgctcatc aggtttagca cattattctc gtcaacttgg tctggtccgg tccagctgca
     9541 ggcgcagacc catatgtgca gcgtttcgaa tctctgcagc cagtcttgaa cagcgggcga
     9601 aaatcggtac catggccaga actacctttc tcgacgtaca aagagattaa caagctcttc
     9661 tgcaaccccg aaatatggct ccgtggcccc tataagatga tgggggctgc ctgcgtcgaa
     9721 agatttgatt tgaagacgac acgggagttt ttcgagagcg tcaaatcctt gagtgaggaa
     9781 tgggaagacc gtggctggtt cagcgccatg tttgagtgtc tgcccgatca gcgcgttcgc
     9841 gaaatctctg atgatgccac ggcatttcca tggcgtgcag gatcaaatca tttcttgtga
     9901 gtcaactcca tccaccactc taacaaaaac agctcctaat gtgagaactg caggatgctg
     9961 aatgctacac caaagcgaat ggaggatcga aaggtctttg aggaccacct caactactgg
    10021 aagagacgtt tcatcgaaac gtctggttat ggcaggttgc agcaatacgt gagctatggc
    10081 aacggcacgt cgactatgaa ggatccgcca gaggcgctat atggttacga gccatggaga
    10141 ttagagaagc tgcggaatct caagcagaag tatgatcccg acaacgtgtt tcgatggtac
    10201 cagccacttc ttgaaccatg aggtcttttt tgccgggtct tgaagtagtt ttcagtacag
    10261 acatagccaa ttagacgata ccatctctga aggtaccatt agaagcaggt tcttttccct
    10321 tgcggatgcg tacgcgtctc tgagctttac gatagctcca tccatgtacc acgaggccta
    10381 tcgagaagtc tagcggctta gcagatttga tgacaactgt ttgccgagga gcgaaagatg
    10441 gcttgcgtag atctcagcat gaaaaaaggc ctgtagatct tgtcccgacc tcaaaaactg
    10501 tccagagctt ggtcgcagaa acgagcggac actttagcgt gtcacgactc atgtcgggca
    10561 tgaaatcgat gcgcagaggc gtgcgatctg gggaaatttc tagagccgac gctgataatt
    10621 gcctgagtat acgggccttc agtgggtcca aagaatgctg gtcaaagtgg tggggacgaa
    10681 agtgaacccc acagcgttga taaccctcgt ttaccccggt cgttttcgtg tgctgaaaag
    10741 attcactccg agagtggcga cccgtcaata ccacgagtca ggacgaccgt ctgtagccaa
    10801 gttgcgctcg tatagtgcag aatgcttgga gagcggaagg aaccgtaatc gcttgagatc
    10861 ggtgtttcga gaacccactc catatactcg ttgcacgtgt gcacccgggg aatcaccagg
    10921 cagcgtgctc aaacaacaaa gtgggattgg atgctttgct caaaatgatt caccgacttc
    10981 atattgatcc tgccgaatcg aagacaagaa ttttcctgga tatggcagct gctcggtgtt
    11041 gacgcgacat ctgtacgatt agtgaaagga tagcagacgt tacctttgaa cacgatatgt
    11101 acttgtagtt tccctccaga tttcgtcgag caatcttccc atcgcatatc ataccccgtc
    11161 atctctcatt tgagtgtctt gtcattcagc tatcgctgat actgacttgc ccaactgcct
    11221 gccattcctc attagcattc ttcatcacaa agctgccacc atggacaagc cagtcgccat
    11281 tattggtatc gcgtttcgtg gacctggtga cgctcgagac ccggaagcct tctaccgcat
    11341 gctcgtcgag ggtcgtaacg cacgcaccga aatccccaag gaccgttaca atgtcgacgc
    11401 tttctatcat cctgattcag aacgcctagg cagtattcaa caaaggtagg ctcgacgcca
    11461 ttcttcctgt tatatgccca ggatgctgat cgcttgttac aataggcatg cccacttctt
    11521 gcaacaggac ttcaaggtgt ttgatgctcc attcttcagc atcacaccga aggaagcaaa
    11581 ggccatggac cccacgcatc gcatcctttt ggaagctaca tacgagggct ttgagaatgc
    11641 cggcttgagc ttggagaagg tttcaggcac acagacgtcc tgctacattg gcaccttcac
    11701 agcagacttt cccaacttgc aagcacgtga taacgaaggt ccttcgatat accacgccac
    11761 tggcatgtca gcatcgctgg cttccaacag attatcgtgg ttctacaatc ttcggggccc
    11821 ttccctaaca gtcgacacag cttgctcatc cagtttgact gctttccact tggcatgtca
    11881 aagcattcgc acaggagagg ctgaaatgag cgtggttgga ggcgccaatc tcatgttcgg
    11941 accagacatg tccatcttgt taggggctgc gaagatcctg tcgccagaag gcaagagcaa
    12001 gatgtgggat gcgaatgcga atggttttgc tcgtggagaa ggatttggcg tcacgatcct
    12061 gaaggtacgt acccggcgca atcgttactt ttcagggtga gacatttggc tgacaagtga
    12121 cgatacgtag cctctagacg cagcgttgcg cgacggtgac aacattcgag cggtcgtgct
    12181 ggccacagct gccaatgaag atggccacac gcctggtatc tcgctgccta acagtgaggc
    12241 gcaacaagaa ttaatccgga gggcatacca gatagctggc gtagatccag cagagacggc
    12301 gtatgtggaa gcacatggaa ccggtacaca ggctggtgac ccactggaag cccgagccat
    12361 cttgaaaacc attgggtcgg tcgagggccg caagtcggat ctctacgtcg ggtctgttaa
    12421 gacgaacatt ggacatctcg agggtgcagc cggtgtagct ggtatcatca aggctgcact
    12481 gacggttgag cgaggcatga taccgccgaa tctttggtca gtatatccgt gaaaacctct
    12541 atcatccccg tactgacgac ctccaggttc gagaagctca atcctgagat cgatttgcca
    12601 gacaatgtca agattgcctc caaattgaca ccctggccac atagcggacc tcgccgcgca
    12661 agcatcaaca gcttcggttt tggtggtgcg aacgcacatg ctatcctcga ggatgcagca
    12721 tcgttcctgt cacgtcatgg cctgagcggt cggcatacga cggcaccgct tcttcccagt
    12781 ctgagcagtg tgcgcgtcag tcaccccagt gacagcccca gcagctctgc aagcacagtc
    12841 gccgaagagg caacaagtgg cgaatctagc gataacatca gtgacgtttc gagcgaggtg
    12901 ctgcgtgacg tctatcccat accgaagttg ttcgtgctat cttcccatga ccaagagggg
    12961 gtcaagcgca gtgccgagcg cctacaagag tatctcgctt ccaagacctc caccacacct
    13021 tcattcctca acgatctggc atacacgctg agtgccaaga ggactacgtt gccatggaag
    13081 tcttacgcag tgtcttcaag tgtcagcggc cttcgagaaa agatctcaag cctccctccg
    13141 gtggtccgct cctctacttc tgcgatacca cgaatcgcct tcgtcttcac tggccagggc
    13201 gcacaatggc acgcaatggg aagaggcctt tccgtgtaca agacttttgc tgagagcttg
    13261 cagagatcgg aggtcatgct caagtcgttc ggttgcccat ggagccttgc tgaagagctg
    13321 agtcgcagca aggctgaata caagctgcgc gagaccgact acagccagcc ggcctgcaca
    13381 gccatccagg ttgcgctcgt agatctcttg agcggcttcg acgtgcggcc tgtcgctgtc
    13441 ctcgggcatt ctagtggcga gattgcggct gcttacgctg ccggctttat cgaccaagag
    13501 gcagcaatca agatcgcttg gctcagaggt caagtcaaca agactgtctc caagaatggt
    13561 ggcatgttgg ccgtttctgc cagcgccgat agcatacaga gtcatctcga cggcctgaag
    13621 agcggcaagg cagtcgtagg atgcttcaac tccaccaagg cttgcactgt cactggcgac
    13681 acctccgcca ttgatgagct acagacaatg ttgaaagacg cacaggtagc atgcacccga
    13741 ttgcccatgg atgttgcata ccattccttc cacatggagg cagcccgcga gaagtacgaa
    13801 caggctctcg aaggtatcgc gcatggctcg acgtcgacca ttcctatgtt ctcctcggtg
    13861 acgggcaccc tggttgaccc ggcacaaatg aagccttctt actgggtaga caacttggtt
    13921 tctcccgtca actttgtcgc ggccacccgc tcccttctga gtcacccgca ggagagcaaa
    13981 tcgcgcaaag cttttgccaa tctgttcgtt gagctcggcc ctcactcagc cctgcgcagt
    14041 tacctcttgg acatcatcag cagcgagaac cgtgctgcgg atacgacgta caccactctt
    14101 ctccgccgca atttcgatgg cgctgcgacg gcgctggaag ccatgggcca tctttgggcg
    14161 catggatgca aggtcgatct gagcaaagtc aacgatgtgt cttctgatag cacaaatatg
    14221 ctgatcgatc tccctcccta cgcttggaac cataagccgt attgggatga atcccacttg
    14281 agccgtcagc accgccttcg caagtcaccg cgtacagacc tcgtaggcta tcgcctactt
    14341 ggaacgccag agcacacatg gcgcaacttc ctacggtgca acgagaaccc atggattcgc
    14401 gagcataagg tccagggcga tatcctctac ccaggtgctg gtatgctcgt catggcgatc
    14461 gaggcggcgc accagctagc ccaagagacg agtgccgacg agatctatgg tttcgaattg
    14521 cgcgatgtca gcatcgatac cgctcttcgc gtacctgaca ctgagaaggg catcgaagtc
    14581 atgacgcagc tgcacaaccg tcgcactgga acacgagcag cgccgtcctc cacgctttat
    14641 gagttcactg tttcttcttg gagtgaagag atgagctctt ggagtacgca tgctcgtggt
    14701 ctagtctcga tcaccttcaa gaccttctct ccgtccatgg agcgcgaggt ggcacttgga
    14761 aacgagcgct acatgtcttc ccttgccgag gttagaagag tctgccagac gccggcgcga
    14821 agcttcttat atgacacagt cgagaccatt ggcatgcaat acgggccgac cttccgcaac
    14881 atgacggagc tgtatgctgg gcccaacagc agttatggtg tcatcaatgt acctgacacc
    14941 aaggcgatca tgcccaaggg ctttgagttc ccccacgtag tccatccggc caccctcgac
    15001 tcggtccttc acctcatctt ccctagcatc tccggcgaag accaggcact gaatgaggcg
    15061 gtcgtccccc gatcttttga tcgcatattt gtctcagcca gtataccgaa gaatgctggc
    15121 gcagagctac gcggttgctc ctctgcaaag aagctgagct acacgacgtg gaattcgaac
    15181 atcaccatgt cagatgcgac gatgactgag cctgttgtca tcatggaagg cgttgtacta
    15241 gcatctgttg gcgctacaga agatgcatca aagcaactgg aaacgcgcgc atcgtgcttt
    15301 gcgcagaact ggcacgtaga tgctgatctc ctgactccat cccagatcaa ggagatcatc
    15361 tacaagcgta cactgaagag taaggatgac gactcagtac ttgatctgct cgagtttgtg
    15421 tgcctggtgt acatctaccg catcctcgac tggttccaga ccgaggaagg gaagccacat
    15481 gtgccacggg atggcttctg gaagtcatac gtagagtgga tgcatgacac tgtcaagcaa
    15541 ttccctgcgc tacccgcaga tgtcgagact gagatggaga aagcccggca gcgcatcgtc
    15601 aagtccgaga gcggcgacat cacggtgcaa atggtggatc gcattgggca aaatctttct
    15661 cgcatcttca cccgcgaagt cgaagctctg caatgcatga ctgagggcga tcttctttac
    15721 tccttctacc gcggcgcgtt cggaaccagt ttcaacacca atgtcgccga gtacgtcggt
    15781 ctgattgctg acaagcaacc cgggttgcgc atcctggaaa tcggggccgg aacgggtggt
    15841 actacatacc atgttttgga acgcttgcgc aatcccgatg gaacctccaa ggcagctcag
    15901 tattacttta ctgacatctc ccccggcttc cttgccaagg cagctgatcg gttcaatcag
    15961 gatgcgtcta ttatgcaatt tggcacgctc aacatcgaga acgcgcctac agagcaaggc
    16021 ttcagccctg aattgttcga cctcatcgta tgcgcgaacg tacttcacgc tacgaagagc
    16081 atccaagaga cattgacgca ctgcaagctg ctgctaaagc caggtggccg tctcgtcttg
    16141 tccgaggtga ccatcaagcg catcttctct gggttcatta tgggtccttt gcccggctgg
    16201 tggctgggag aagcggacgg tagaatggga ggcccgctgt tggatgctga tgagtggaac
    16261 gtcgcattga agaaggcggg attctcgggt gttgatgtcg atgtccgcgg tgatcgtgaa
    16321 acctcgaaag agcccgtctc gctactcatc tcaaccaagc ccaagacgac cgcgcctagc
    16381 ctgccttcct gccttgtcat caccactggt actgaagcgt cgaacatgct agctgatacc
    16441 atacagaggg tatttacctc tgctggtcat gacatcagca tcgctcagtg gaatagtgtc
    16501 accaagacgc aggtagaggg aaagtattgc ctctgtcttg cggaatggga ggatgctatc
    16561 ctcgtgaacc tcaccgatga tgattgggac aggttgcgcg aagtcgttct ttcatccgaa
    16621 ggcgccctgt ggatcactgg tggtggtgct ctcgacaccc cgttccccat gaagagtctt
    16681 atggttggac ttggaagagc tattcgtaac gaagacgccg gcgtccgcct tgcctgtctc
    16741 gatctggatc caccaacgac tatcgacttc gaggaggcgt ctcggactac actcaaggtt
    16801 gcatatgcgc atatccgcgg tgatggcaca gagggtgagt ttgccgcgca tggagacaag
    16861 gtctacgtac cgcgcgtcga gcggaccctg caagttgatg gatcattgcg caagtatgaa
    16921 gccaagggtg atcccgagat ggttccattc aagagctgcg gacgtcccct caagctgact
    16981 atcaagacac ctggtctgct tgataccttc cagtgggaag aggatgagac gtaccacacg
    17041 ccattgcccg aggattggat cgagattgag gtaaaggccg taggtctcaa cttcaaggat
    17101 gttctcgttg cgctcggtaa tctggccgaa aacaagctgg gtgttgatgc ctcgggtatc
    17161 gtcactcgtg ttggatctgc tgtcacgaac gttcaagtcg gcgacagagt aatgacggca
    17221 tcttgtgaca ccttcgccac atacgtccga tttccagcca agggcgccat aggtgttcca
    17281 accggtatga gtttcgagga agccgcttcc atgcccctca ttttcctcac ggcttactat
    17341 gctctggtaa ccgcgggtgg tattgtcgct ggcgagaagg ttctgattca tgccgctgct
    17401 ggtggtgtcg gacaagctgc catcatgatt gcgcaagcca aaggtgctga gatctttgct
    17461 acggtcggcg cagacaccaa gaaacagctt ctgattgagc agtacggaat tccggaagac
    17521 cacatcttca gcagccgcga taccagcttc gtgaaaggcg tactgcgtgc tactgacggt
    17581 caaggtgtgg atttggtcct gaattcgttg gctggcgagg ctctgcgtct atcatggact
    17641 gactgcttag ccaaattcgg tcggttcttg gagattggaa aggcagatct gttcgccaac
    17701 accggtctcg acatgaagcc cttgctggac aacaagagct atattggcgt caaccttctt
    17761 gatttcgaga acaatccaac gcctcgtgcc gtagcgctat ggcatgacac cgcgaagatg
    17821 atccatgacg gggcgatcaa acccatcgcg ccgcttcagg tcttcaccat ggctgaagtg
    17881 gagaaggcct tccgccatat gcaggccgga aagcacatgg gtaaggtggt cgtccgcgtt
    17941 gacgatgccg acgtcgttcg tgccgtaccc cgaatccctc gcgttagcat ccaccccgac
    18001 gcaacataca tgattgctgg actgggtgga attacacgtg agatcgcgcg ctggctggca
    18061 gaaaagggcg cacggtactt agttttcctc tcgcgctctg cagccagcgg cacagacaac
    18121 caggcttttg ccttgcaact gcgaaatacg tacgacgtta cgccgctggc ctatgactgc
    18181 gacgttggaa acaaggcagc tctacaagca gtcttggatg acctgaaggc caagggcttg
    18241 ccacccatca atggatgtgc gactggtgcc atggtcctgc aagactgcct gttcgacaag
    18301 atgaccgccg accatgtacg cacaacggtc ggtcccaagg ttcacggcac ctggaacctg
    18361 catgagctac tgccgcgcga catggacttc ttcgtgatgt tgtcttcgct agctggtgtt
    18421 atgggccatc gcggacaggg caactacggg tgcggtaaca acttccagga cgagtttgct
    18481 tcattccggc gcggtcaggg cctgcccgca atgactatcg atattggcta tcttttgtcg
    18541 gtaggatttg tggctgagca tgacgagtat gtcgatcacg tcaaggccat gggattgaag
    18601 gtgatgcata cctcggacct gcacggtctg gtagcgaccg ccatcgaagg cccctcgcag
    18661 caccccgggc aagtcatgtg cggcctgccc ttcaacgaac acgacgacgc gtggtactgg
    18721 atggctgacg cgcgatttgc tgccctacgc aacgtcgcgg ccgggtccgc tgccaatgcg
    18781 gggcaggcta tttcgctgcg ggaagagttg acgcgttgcg gcaccgtgaa tgaagaggct
    18841 gtgcagctca tcacagcagc catcgcgcaa cgacttgcga gcttgatgat gatacccgag
    18901 gccgacatcg atgctggcag gccgttgagc gcctatggtg ttgacagttt ggtcgcggtt
    18961 gaggtgagga actgggttgc ccgcgaaatg gcagtagagg tttctgtgtt tgatgttatg
    19021 cagaacgtgc cgatgacaca actggcacaa aatttggcgg aaaagagcaa attgctcctt
    19081 ggccaggctt gaggttgtat atactagata gtgttgatga aaataacttc ttattgtata
    19141 cactatccca tgcgacgctc gtgatgccag cagagagatg agggaatgag tagggccgac
    19201 cagccacact gaggctggct gagccataga ccctgattgg acaatgtgcg atcataacgt
    19261 cattgactcg tggaacggtt tggtcgtcac tacccctatg ccacgaaatc gatctagatt
    19321 catgtaggaa cgacgatgtt gcgtagctgt ctaattagtt cgaaaatgtt cataacaaca
    19381 cacaaactcg tcagtccctc catctggcag gtcagctcca tcgaatttct ttgcccatag
    19441 cccagtcaca actattgcat tagtccacta tcatgtcggg caacgttgta gaccctgaag
    19501 caagggataa atatctccta caaggtgcgt gatagtcaac gcaaggtgat tgttcaaaat
    19561 actgatgttc agtagtaagc gccggaccat cctacaatac ttcggagcac gagcaggtgt
    19621 cagtcaacgg cccagacccc acatatgtcg aaagcgaact tgtagatgca tggattcgcg
    19681 tccggatcaa ggactaccat ggcctgcccc gtggttcccc agcttcctcg tcttacttcg
    19741 agcacccgca acatacctct gataggtact cgattgccta ctcctttgtg cccaaggaag
    19801 acatgtccgg ttccgatctg gtaatgggct tcgattacgg tcactctatc aaacaccagc
    19861 ttccaccggg tttcaaatac gcaatgaaga ttgctacaag catgcttgat cctgggcttt
    19921 attcagacgc atactctgac gagccctact tatacgggcc cgcactctca agtttctttg
    19981 ctttcagaat tggggaccga acgagcgaag tgtcagcaaa agaccaactc gcaaatctga
    20041 gtcaagaaac agacagtgtg atagaggaag gtgcatccgg aagtggcaaa gaagttcgaa
    20101 aagctttgtc tatgccttca aagtggaaga agaggcggaa gcattttctc gacaaacaag
    20161 ccctctcagc cttcaccttt gagaaaggcc gcatgtatca cgctgacttc ttcaacccgc
    20221 accttgattt tgcgaatttc tcgttgaggt taccgggctt ctccatcagt gtggccaagt
    20281 atgtggacga gaaaacgcat catttgaggt atgtgctcaa gaaccggagg acttcagatg
    20341 tgcttctcgt cgtctttttc aaattgttat ttggcaaaga gctggaagat acgctggaga
    20401 aggagaagag gagagaaagt gcatcattag ctgtggctgt ggacgatcaa ccgaaagagg
    20461 agagcacagg ccatgccgaa ttaaccaagg cttgtgctga ggaggctgaa ccaagagctc
    20521 cagaacctca accatcgcta gtacaacggg atgagtcctc tccaaggcaa catgcaggta
    20581 cggatggtgc aacagcagga agggcgaccg gggttgacga caagccacaa gaagatcaga
    20641 gctacatcgg ccaagcaaca gccgctgtgt cgaatcttgc aaactccgta gtggcagtgt
    20701 acgcagcgct gggcttcggc aattcgtcat cctcatcgtc cgactcagag ggctcaagta
    20761 ggaggagtag ctcatcacag ccaccaaaca ggtcaatggc aactgagatc gataacatgg
    20821 atgacaagac aatagagcag tacttgaaaa gtcgacaggg aagcgtatga ggttttctgt
    20881 agaccaagta agtatcgagg caatggcgtt gtacaacctc ataatgatgt ggaccagaat
    20941 gactcttctt ccatgattgc tgtctcgtca tttcacgatg accatgtggc gggagcactt
    21001 ttgcagaaag tgcaatctcg tgttgaagca agaatctaca acaggtggag agaacgacga
    21061 gaggactgcg gcagtcggta tccggcaacg ccagccttag atcgcctagc gtgcacgtgc
    21121 actcagcccc acattcatct cgaagccgat gaaactccgg agatgtctcc ttgacacacg
    21181 ctctgcaccg cacagcatcc aaaaggcaac attacacgct ctcataccgc gtggcgctga
    21241 gattaagcca ctccagtcag cccgtgttca agtttatagc aactgcacgc gtcagggcgc
    21301 atccgagcgc tcggtagcct acctccatac ggatctgcgt ctcggaaact gatgcttcca
    21361 tggcactaag cacgttttgt cgtggaaaga ctgcccacag gacagcgcga cgcaaggatg
    21421 atttgcggta aagtactgat tcatccggcg tctgtcttcc cgcgacttgc gggtatctgt
    21481 gttccagtaa gaatcgtctt gaggcacttt tagtggcgcg gattcatgcg ttgccggtcg
    21541 ttgtggttct cttatgtagc tggaaaatta tctccccacg ccaatggcgg gtttgtataa
    21601 tctcttcttt cttatgatca tcacctgcgt agtgctacca tagctacggt atcggtccgt
    21661 tgcgaaaatt caggaatcat gataagtact tgtttagacc tcgcactcct gtgccacccg
    21721 gtactcgcat tcctcacgat acatcgacca aagatggcgg ctcaacaatc gaaatggcag
    21781 tactttttcc tcagcttctt tgcattgctc gctatgcgct atgctagcac tacgaacgct
    21841 actcctcaag caccgcaaga aatcgttcag gctgcctgcc agacggttga ccagccaaat
    21901 cccattgcgt cactctaccc gatgaacgcg acaggagtac ttaacggcac tgtgtcggta
    21961 gtaccgatat c
//
