BGC0000013 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000013 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	45,963	High	alternariol	PKS

BGC0000013 - Region 1 - T1PKS

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Location: 1 - 45,963 nt. (total: 45,963 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 45,964
Label		BGC0000013

Tailoring functions

Hydrolases: hydrolase

ANIA_07070: metallo-beta-lactamase family protein

smcogs: SMCOG1170: metallo-beta-lactamase family protein

Ligases: synthase

ANIA_07071: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000013.3	1.00	PKS	alternariol	Aspergillus nidulans FGSC A4
BGC0002237.3	0.75	PKS	dichlorodiaporthin	Aspergillus oryzae RIB40
BGC0002507.3	0.75	PKS	sporandol	Chrysosporium merdarium
BGC0001284.4	0.67	PKS	alternariol	Parastagonospora nodorum SN15
BGC0001144.4	0.66	PKS	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0001257.3	0.64	PKS	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002646.3	0.64	PKS	hancockinone A	Aspergillus hancockii
BGC0002154.2	0.64	PKS	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001258.3	0.64	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000107.3	0.64	PKS	naphthopyrone	Aspergillus nidulans FGSC A4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000013.3	1.00	PKS	alternariol	Aspergillus nidulans FGSC A4
BGC0002237.3	0.75	PKS	dichlorodiaporthin	Aspergillus oryzae RIB40
BGC0002507.3	0.75	PKS	sporandol	Chrysosporium merdarium
BGC0001284.4	0.67	PKS	alternariol	Parastagonospora nodorum SN15
BGC0001144.4	0.66	PKS	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0001257.3	0.64	PKS	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002646.3	0.64	PKS	hancockinone A	Aspergillus hancockii
BGC0002154.2	0.64	PKS	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001258.3	0.64	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000107.3	0.64	PKS	naphthopyrone	Aspergillus nidulans FGSC A4

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 45963:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ANIA_07071: mal

PKS_AT (947..1281): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 106.5
inactive: 61.2
Methylmalonyl-CoA: 49.5
Methoxymalonyl-CoA: 45.8
Propionyl-CoA: 40.1
Benzoyl-CoA: 17.6
Acetyl-CoA: 17.6
2-Methylbutyryl-CoA: 17.2
Isobutyryl-CoA: 16.7
Ethylmalonyl-CoA: 14.8
CHC-CoA: 14.5
fatty_acid: 11.6
3-Methylbutyryl-CoA: 8.5
trans-1,2-CPDA: 0.0

Link to PARAS substrate predictor