LOCUS       BGC0000013              7849 bp    DNA     linear   PLN 27-FEB-2015
DEFINITION  TPA_asm: Aspergillus nidulans FGSC A4 chromosome IV.
ACCESSION   BGC0000013
VERSION     BGC0000013
KEYWORDS    .
SOURCE      Aspergillus nidulans FGSC A4
  ORGANISM  Aspergillus nidulans FGSC A4
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Nidulantes.
COMMENT     Aspergillus nidulans FGSC A4 CADRE,
            updated by Eurofungbase with contributions from
            CADRE (http://www.cadre-genomes.org.uk),
            AspGD (http://www.aspergillusgenome.org) and
            Ensembl Genomes (http://www.ensemblgenomes.org).
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 14:34:04
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1119809
            Orig. end    :: 1127658
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..5963)
                     /locus_tag="ANIA_07071"
                     /old_locus_tag="AN7071.4"
     CDS             complement(join(1..1383,1455..3533,3594..3923,3975..4379,
                     4474..5515,5590..5963))
                     /NRPS_PKS="Domain: SAT (38-279). E-value: 2.1e-51. Score:
                     166.6. Matches aSDomain: nrpspksdomains_ANIA_07071_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (419-840). E-value:
                     7.1e-132. Score: 432.1. Matches aSDomain:
                     nrpspksdomains_ANIA_07071_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (947-1281). E-value: 2.8e-81.
                     Score: 265.0. Matches aSDomain:
                     nrpspksdomains_ANIA_07071_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1363-1704). E-value: 1.3e-81. Score:
                     266.2. Matches aSDomain: nrpspksdomains_ANIA_07071_PT.1"
                     /NRPS_PKS="Domain: PP-binding (1805-1868). E-value:
                     8.5e-16. Score: 50.1. Matches aSDomain:
                     nrpspksdomains_ANIA_07071_PP-binding.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00000398"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00000398"
                     /db_xref="GOA:Q5AXA9"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016038"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="UniProtKB/TrEMBL:Q5AXA9"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 69.9; E-value:
                     2.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ANIA_07071"
                     /note="transcript_id=CADANIAT00000398"
                     /old_locus_tag="AN7071.4"
                     /product="polyketide synthase, putative (JCVI)"
                     /protein_id="CBF79143.1"
                     /sec_met_domain="PP-binding (E-value: 3.1e-17, bitscore:
                     50.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1e-82, bitscore: 265.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 2.2e-137, bitscore:
                     445.3, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTPSASPSPSPNPGDANVKVDADSPNDFILFSHELPSGDIQDLIR
                     RLHRYGTLPGYPHLARFLQECALLLRTEIQKLPRALRDSVPPFHDVVTLASHWDRLKSG
                     PLSGAWDGPFLCLYEIAMLIGHHETHQLSYRRPACLVGISVGLFSAAAVAVSKSISDLV
                     SYGAESVRTAFAFCVHVQRVSQELEPTMTEQAASVSWATVVIGVPADTIQVELDRFNHL
                     KESESPGANARPLTGVSISHVDQTSVGVTGPPSRLKQLFRQSELLRSSRHSALPISGGL
                     CHVPNVYDDEDVRAILEMAEVWEKWGTRALQVPLISPFTGSPFLCPDAYHLIEAICTEA
                     LTKQLYFDKLAGGVVTQLNGLSCQVLHYGASLMSDTIIDDVTSQLSPCDTARQCLVDWA
                     LRDAFDQLPGGPTPPRDAKLAVVGMACRMPGGADTPDHFWELLMNGVDTHTTVPPDRFD
                     LDAHFDPSGEKENTTTKGSQSNRPLSRQAEQTDPMQRLALVTAYEALEMAGFVPNRTPS
                     SHLSRVGTYYGQASDDYREVNAGQKIGTYGIPGTERGFGNGRINYFFNFQGPSFNIDTA
                     CSSGLAAVQAACSALWAGEADTVVAGGLNVITSPDIYCMLSKGHFLSKTGQCKVWDIGA
                     DGYCRADGIGSVVIKRLDDALADNDVILACISAGATNHSAESISITQPHAAAQRENYRQ
                     VMDRAGVSPLDVSFVELHGTGTQVGDAVESESVLSFFAPLGRRSHPDKRLHLGAVKSNI
                     GHGEAAAGIASLIKVLLMYRNNTIPRHIGIRTAMNPVVAQHLANRNAGILSENHPWLAA
                     TASKKRYAIVNSFGAHGGNTTLLLEDAPSQHSQRYKNHSRRVVASSEVVCTSAKSKASL
                     RANIRALLAYLDTHQETDLRDLAYTTSARRMHHHIRIASSVTSTAQLRSFLQAAADDVD
                     AYAKHIATATKRTAVFAFSGQGCLYHGAAAHLFEQAPLFRNQVLQLDRIVRRLGFPSIL
                     VTVAGDAASVYDSARCPHRESTPSSDASHDSNTNRTSTAPAVDSPLIAQLALVVIQIAL
                     VQYWGLLGIKPSVVIGHSLGEYAALVAASVLSVADALFLVGKRAELMLAVCEPGSHAML
                     SVRGASVDRIEELCRESEKRYPFEVSCVNGLTDLVVTGLRGDMASLRDLLQGSGLKCVL
                     LDIPFAFHSKQMSPILEDFENAAQQITFQEPAVPVISPLLGKCISEANVINGKYLARAT
                     REPVDFVAALDSAWADGTVNDKSIWIDIGPHPVCTSFASNHYGKAATQSFASLRRGDET
                     LSTLTATLAALHCLGLPVDWNEYYDLRENPARLLHLDSYQWNYKNYWIPYEGSWTLDKA
                     HAGQNNKTKDDNSAVTPAFFTSSVQQIIFEEYDESMGRMEALSDLHHPDLQGAADGHKI
                     HGRSVVTGSIWADITLTVGEYLYKQMVPGGKMPHMNVKGMEVLEAQVLHPDMSQFIQIE
                     GVLDLPRQQTAVRLYAASANGTRNTDKPFASATVCYEEAQDWQDQWQMTSHLVAARANS
                     FWEMAAGGSDDNARPAGKGGPRVNNFFRSIAYQLFANVVDYGARYRGMQRVALSEDTLE
                     ATADIVLDKDRHGTWHTPPHWIDSAFQLAGFVMNSFGVQGDGKISGSSRDFFYITPGWR
                     HFRLLERLEPGPEATYRSFVRMFPVGSEPGAYSGDIYLHRGKRLVGVCAGIKFKAVPRA
                     LMPVLFPRIEPQAGKRRNQAQTAENRLVKGKGNCEYTHTVFQEPKSRTPAYDVTKSQPH
                     AEHCDISISQKTQPVAAVPVTQPALPAKERGEQNQGQSQSQNAQATACLSLISDETGLD
                     LDDLTGEAAFADLGVDSLMSLALSAKIRAELGIDVQSSIFLECPTVQDLVTWLSK"
     subregion       1..7849
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..7849
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(join(1..1383,1455..3533,3594..3923,3975..4379,
                     4474..5515,5590..5963))
                     /locus_tag="ANIA_07071"
                     /note="transcript_id=CADANIAT00000398"
                     /old_locus_tag="AN7071.4"
     aSDomain        complement(10..198)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_07071_PP-binding.1"
                     /evalue="8.50E-16"
                     /label="ANIA_07071_PP-binding.1"
                     /locus_tag="ANIA_07071"
                     /protein_end="1868"
                     /protein_start="1805"
                     /score="50.1"
                     /tool="antismash"
                     /translation="SLISDETGLDLDDLTGEAAFADLGVDSLMSLALSAKIRAELGIDV
                     QSSIFLECPTVQDLVTWL"
     aSModule        10..4632
                     /complete
                     /domains="nrpspksdomains_ANIA_07071_PKS_KS.1"
                     /domains="nrpspksdomains_ANIA_07071_PKS_AT.1"
                     /domains="nrpspksdomains_ANIA_07071_PT.1"
                     /domains="nrpspksdomains_ANIA_07071_PP-binding.1"
                     /iterative
                     /locus_tags="ANIA_07071"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(join(502..1383,1455..1595))
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_07071_PT.1"
                     /evalue="1.30E-81"
                     /label="ANIA_07071_PT.1"
                     /locus_tag="ANIA_07071"
                     /protein_end="1704"
                     /protein_start="1363"
                     /score="266.2"
                     /tool="antismash"
                     /translation="TSSVQQIIFEEYDESMGRMEALSDLHHPDLQGAADGHKIHGRSVV
                     TGSIWADITLTVGEYLYKQMVPGGKMPHMNVKGMEVLEAQVLHPDMSQFIQIEGVLDLP
                     RQQTAVRLYAASANGTRNTDKPFASATVCYEEAQDWQDQWQMTSHLVAARANSFWEMAA
                     GGSDDNARPAGKGGPRVNNFFRSIAYQLFANVVDYGARYRGMQRVALSEDTLEATADIV
                     LDKDRHGTWHTPPHWIDSAFQLAGFVMNSFGVQGDGKISGSSRDFFYITPGWRHFRLLE
                     RLEPGPEATYRSFVRMFPVGSEPGAYSGDIYLHRGKRLVGVCAGIKFKAVPRALMPVLF
                     P"
     aSDomain        complement(1842..2843)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_07071_PKS_AT.1"
                     /evalue="2.80E-81"
                     /label="ANIA_07071_PKS_AT.1"
                     /locus_tag="ANIA_07071"
                     /protein_end="1281"
                     /protein_start="947"
                     /score="265.0"
                     /tool="antismash"
                     /translation="FSGQGCLYHGAAAHLFEQAPLFRNQVLQLDRIVRRLGFPSILVTV
                     AGDAASVYDSARCPHRESTPSSDASHDSNTNRTSTAPAVDSPLIAQLALVVIQIALVQY
                     WGLLGIKPSVVIGHSLGEYAALVAASVLSVADALFLVGKRAELMLAVCEPGSHAMLSVR
                     GASVDRIEELCRESEKRYPFEVSCVNGLTDLVVTGLRGDMASLRDLLQGSGLKCVLLDI
                     PFAFHSKQMSPILEDFENAAQQITFQEPAVPVISPLLGKCISEANVINGKYLARATREP
                     VDFVAALDSAWADGTVNDKSIWIDIGPHPVCTSFASNHYGKAATQSFASLRRG"
     CDS_motif       complement(2400..2519)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_07071_0005"
                     /evalue="3.60E-17"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ANIA_07071"
                     /protein_end="1095"
                     /protein_start="1055"
                     /score="54.5"
                     /tool="antismash"
                     /translation="GIKPSVVIGHSLGEYAALVAASVLSVADALFLVGKRAELM"
     aSDomain        complement(join(3165..3533,3594..3923,3975..4379,
                     4474..4632))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_07071_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="7.10E-132"
                     /label="ANIA_07071_PKS_KS.1"
                     /locus_tag="ANIA_07071"
                     /protein_end="840"
                     /protein_start="419"
                     /score="432.1"
                     /tool="antismash"
                     /translation="AVVGMACRMPGGADTPDHFWELLMNGVDTHTTVPPDRFDLDAHFD
                     PSGEKENTTTKGSQSNRPLSRQAEQTDPMQRLALVTAYEALEMAGFVPNRTPSSHLSRV
                     GTYYGQASDDYREVNAGQKIGTYGIPGTERGFGNGRINYFFNFQGPSFNIDTACSSGLA
                     AVQAACSALWAGEADTVVAGGLNVITSPDIYCMLSKGHFLSKTGQCKVWDIGADGYCRA
                     DGIGSVVIKRLDDALADNDVILACISAGATNHSAESISITQPHAAAQRENYRQVMDRAG
                     VSPLDVSFVELHGTGTQVGDAVESESVLSFFAPLGRRSHPDKRLHLGAVKSNIGHGEAA
                     AGIASLIKVLLMYRNNTIPRHIGIRTAMNPVVAQHLANRNAGILSENHPWLAATASKKR
                     YAIVNSFGAHGGNTTLLLEDAP"
     CDS_motif       complement(3402..3446)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_07071_0004"
                     /evalue="3.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ANIA_07071"
                     /protein_end="761"
                     /protein_start="746"
                     /score="10.2"
                     /tool="antismash"
                     /translation="GAVKSNIGHGEAAAG"
     CDS_motif       complement(join(3516..3533,3594..3623))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_07071_0003"
                     /evalue="9.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ANIA_07071"
                     /protein_end="723"
                     /protein_start="707"
                     /score="11.6"
                     /tool="antismash"
                     /translation="FVELHGTGTQVGDAVE"
     CDS_motif       complement(4026..4094)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_07071_0002"
                     /evalue="8.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ANIA_07071"
                     /protein_end="590"
                     /protein_start="567"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPSFNIDTACSSGLAAVQAACSA"
     aSDomain        complement(join(5053..5515,5590..5849))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_07071_SAT.1"
                     /evalue="2.10E-51"
                     /label="ANIA_07071_SAT.1"
                     /locus_tag="ANIA_07071"
                     /protein_end="279"
                     /protein_start="38"
                     /score="166.6"
                     /tool="antismash"
                     /translation="DIQDLIRRLHRYGTLPGYPHLARFLQECALLLRTEIQKLPRALRD
                     SVPPFHDVVTLASHWDRLKSGPLSGAWDGPFLCLYEIAMLIGHHETHQLSYRRPACLVG
                     ISVGLFSAAAVAVSKSISDLVSYGAESVRTAFAFCVHVQRVSQELEPTMTEQAASVSWA
                     TVVIGVPADTIQVELDRFNHLKESESPGANARPLTGVSISHVDQTSVGVTGPPSRLKQL
                     FRQSELLRSSRHSALPISG"
     CDS_motif       complement(5407..5484)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_07071_0001"
                     /evalue="9.90E-02"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ANIA_07071"
                     /protein_end="161"
                     /protein_start="135"
                     /score="5.8"
                     /tool="antismash"
                     /translation="RPACLVGISVGLFSAAAVAVSKSISD"
     mRNA            complement(join(6559..6627,6753..7496,7640..7849))
                     /locus_tag="ANIA_07070"
                     /note="transcript_id=CADANIAT00000399"
                     /old_locus_tag="AN7070.4"
     gene            complement(6559..7849)
                     /locus_tag="ANIA_07070"
                     /old_locus_tag="AN7070.4"
     CDS             complement(join(6559..6627,6753..7496,7640..7849))
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00000399"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00000399"
                     /db_xref="GOA:Q5AXB0"
                     /db_xref="InterPro:IPR001279"
                     /db_xref="UniProtKB/TrEMBL:Q5AXB0"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     157; E-value: 7.2e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ANIA_07070"
                     /note="transcript_id=CADANIAT00000399"
                     /old_locus_tag="AN7070.4"
                     /product="conserved hypothetical protein"
                     /protein_id="CBF79145.1"
                     /transl_table=1
                     /translation="MSGGFYSSPFWAGYLETQRSRLPVLPEIDDGLSHCVVRFLGYNPG
                     SMQLQGTNTYLVGTGSTRILIDTGEGAPQWAVSVTRYLEDHDISISHVLLTHWHKDHTG
                     GVADLLAHDPSIIVYKHAPDPGQQAIANGQTFKTQGATLRAVLTPGHAVDHMCFLLEEE
                     NALFTGDNVLGHGYSVAEDLETYTASLRLMAGLKCSVGYPGHGDAILNLPQTIARYISQ
                     RVAREKKIYAILALHACSCSSRNGGSTSSIGSVSESGDSDEEDNNMKTSRPAMQGLSTA
                     EIGGLVYGESVKNSPTFDSAVGPLLNQVLYMLLEQGKCCDHVSILVIFQKPGFFSIPVI
                     "
ORIGIN
        1 tcacttgctc aaccacgtca ctaagtcctg tacagtagga cactccagga agatggacga
       61 ctgaacgtca attcctaact ctgcgcgtat cttggccgat agcgccagtg acatgagaga
      121 atccacgccc aagtccgcaa aggcagcttc gccggtcaag tcgtccagat ccagccccgt
      181 ctcatccgaa atcagtgaca ggcacgcggt tgcttgcgcg ttttggcttt ggctttgacc
      241 ttgattctgt tcaccccttt ctttcgcagg tagagctggc tgtgtgactg ggactgccgc
      301 taccggctgg gtcttttgcg agatgctgat gtcacaatgc tcggcatggg gctgcgactt
      361 ggtcacatca taggcaggcg ttctagactt gggctcttgg aaaacagtgt gagtgtactc
      421 gcagttgcct ttgcccttga ccaaacgatt ctcggctgtc tgggcttgat ttcgtctctt
      481 gccagcttgt ggctcgattc gaggaaacaa aaccggcatt aaagcgcgag gaaccgcttt
      541 gaacttgatg cccgcgcaca cgcccacgag ccttttccct cggtgcagat aaatgtctcc
      601 cgaatatgcg cccggctcac tgccgactgg aaacatccgg acaaagctgc gatacgtggc
      661 ttcaggcccc ggctcaagac gttccagcag cctaaagtgc cgccagcccg gcgtgatata
      721 gaagaaatca cgagacgacc cggaaatttt gccatcgcct tgtacgccaa atgagttcat
      781 gacaaagcca gcgagctgga acgcgctgtc gatccagtgc ggcggcgtat gccaggtgcc
      841 gtggcggtcc ttgtctagga cgatgtcggc cgttgcttcg agcgtgtctt cggagagggc
      901 aacgcgctgc atcccgcggt acctcgcgcc gtagtctacc acattggcaa aaagttggta
      961 cgcgatgctg cggaaaaagt tgttcactcg aggtcctccc ttgcctgctg gccgggcatt
     1021 gtcgtctgat ccgcctgctg ccatttccca gaacgaattg gctcgcgcag caacaagatg
     1081 cgaggtcatc tgccactgat cttgccagtc ctgagcctct tcgtagcaaa cagttgctga
     1141 ggcaaacggc ttgtcggtat tccgagtgcc gtttgcgctt gctgcgtaca gccggactgc
     1201 cgtttgctgt ctgggtaggt ccaagactcc ctcaatttgg atgaattggg acatatctgg
     1261 gtgcagcacc tgggcttcca ggacttccat ccctttcacg ttcatgtgtg gcattttgcc
     1321 gccgggcacc atttgcttgt acaggtactc acccacagtg agggtgatgt cggcccagat
     1381 actctgtgca atgatgcagt tagtaaatct gtccatgtgc aaagatcaga gaatcaggga
     1441 ttgcaatatc atactccagt cacaacactc ctcccatgta tcttatgccc gtctgctgct
     1501 ccctgcaggt cggggtggtg caagtcggag agtgcctcca tccgtcccat cgactcgtca
     1561 tattcctcga aaatgatctg ctgcaccgag gaggtgaaga aggccggagt gaccgcggaa
     1621 ttgtcgtcct tggtcttgtt gttttgtcca gcatgagctt tgtcgagcgt ccatgagccc
     1681 tcatatggga tccagtagtt cttatagttc cattggtacg agtccaggtg cagtaggcgg
     1741 gcagggttct ccctgaggtc atagtactca ttccaatcaa ccggaaggcc caggcagtgc
     1801 agggctgcca gagtcgccgt caatgttgat agcgtctcgt caccgcggcg cagtgacgca
     1861 aagctttgtg tggctgcttt gccatagtga ttgctcgcga aggaggtaca gactgggtga
     1921 ggcccgatat caatccagat ggacttgtca ttgactgtgc catctgccca agcagagtca
     1981 agtgccgcca caaaatctac tggctcccgt gttgcgcgag ccaggtactt cccattgatg
     2041 acattagctt cagaaatgca ctttcccagt agtggagaga tgacggggac cgcaggttct
     2101 tgaaaagtta tctgctgagc tgcattttca aagtcctcca ggatgggcga catttgcttg
     2161 ctgtggaacg caaaggggat atcaaggagg acgcatttca gcccggaacc ctgcagcagg
     2221 tcacggagag aggccatatc gcctcgcaga ccggttacca caaggtcagt cagtccattc
     2281 acacatgaga cttcaaaagg ataccgtttc tcgctttctc ggcacagttc ttctatgcga
     2341 tccacggagg cgccgcggac ggacaacatg gcatgactcc ctggctcaca gacggccaac
     2401 atgagctcgg ctcgctttcc caccaggaat agagcgtctg ctactgatag aacgctggct
     2461 gcgaccagcg cagcgtattc gcctaggctg tggccgatca ccacgctggg cttgatcccg
     2521 agcagccccc aatactgcac caaggcgatc tgtatcacca ccagggcaag ctgagcaatc
     2581 aatggactgt ctactgctgg tgccgtagag gttctatttg tgttgctatc atggctcgcg
     2641 tcgctactcg gggttgactc tctgtgggga catctggcgg agtcgtaaac acttgctgca
     2701 tcaccggcta cggtgaccag tattgatggg aatcccaggc gccgaacgat gcggtcaagt
     2761 tggagaacct ggttgcgaaa caaaggtgct tgttcaaaca gatgagccgc agcgccgtga
     2821 tagagacagc cctggccaga gaaagcaaac acggccgtcc gtttggtggc ggtcgcgata
     2881 tgttttgcat acgcatcgac atcgtcagcg gcagcctgca ggaaagaccg cagctgtgca
     2941 gtgctagtaa cagagctggc aattcggata tggtggtgca tccgccgagc gctcgttgta
     3001 taggcaagat ctcgaaggtc cgtctcttgg tgagtgtcga gataggcgag caaagccctg
     3061 atattggctc gaagcgaggc tttgcttttg gccgaggtgc atacgacttc gctgctggct
     3121 accacccgtc gcgagtggtt cttgtatctc tgactgtgtt gcgatggcgc atcctcgagc
     3181 aacagcgtcg tattgccgcc atgggcaccg aagctgttca caatagcgta ccgcttctta
     3241 gaggccgtcg cggcaagcca tgggtggttc tcggacagga tcccagcgtt gcggttggca
     3301 aggtgctgag ccacgaccgg gttcatggcc gtccggatgc caatgtggcg gggaatcgtg
     3361 ttgttgcggt acatcaacag aactttgatg agggaggcaa tccctgcagc tgcttcgccg
     3421 tgcccaatgt tggacttgac ggcacccaga tgcagacgct tgtctgggtg tgaccggcgg
     3481 cctagaggcg caaagaagct aaggacagac tctgattcca cagcgtctcc aacctattca
     3541 ccagacgctg atgtcagccg tacaagtcta taaaagtcat tcaatggaca aacctgagtt
     3601 cctgtgccgt gcagctcgac aaaactaacg tccagtgggc tcacacctgc cctgtccatc
     3661 acctggcgat agttttccct ctgcgcagcg gcatgcggtt gagtaataga aatactctct
     3721 gcggaatggt tcgtagcacc ggctgatata caagccaaaa tgacatcgtt gtcagcaagg
     3781 gcatcgtcca ggcgcttgat cacgacagac ccaatcccgt ctgcacggca atacccatca
     3841 gcgccaatat cccacacctt acactggccc gtcttggaca ggaagtggcc tttgctcagc
     3901 atgcagtata tatccggact cgtctaaagg gtttcagtaa ttgaacagta gtagacacgc
     3961 agttcccaac ttacaatgac gttcaatccc ccggcaacga cggtatcggc ctcgccagcc
     4021 caaagcgctg aacaggctgc ctggactgca gctagtccgc tggagcatgc ggtgtcgatg
     4081 ttgaaactgg gcccttggaa attgaagaag tagttgatcc gcccgttgcc gaaccctcgt
     4141 tctgtcccag ggatgccgta cgtgccaatc ttctggcccg cattgacctc gcgatagtca
     4201 tcgctagcct ggccatagta agttccaacc cgtgagaggt gagaggacgg ggtgcgattc
     4261 ggcacgaagc cggccatctc gagagcctcg tacgccgtaa ccagtgctag tcgctgcatc
     4321 gggtctgtct gctcggcctg gcgggagagt ggtcggttag actgtgaacc tttggtcgtc
     4381 tgtttgcgtc cttacctcgc gtggggacat attgaagaat cccgcgtcaa aataccctgg
     4441 gttggcgata aagttgccaa atcgggtccc aactgtattc tccttttcac cgctggggtc
     4501 gaagtgagca tccagatcga accggtccgg tgggacagtt gtgtgagtgt cgactccatt
     4561 cattagcagc tcccaaaagt ggtcgggggt gtctgcacct cccggcatgc gacatgccat
     4621 gccaacgaca gccagcttcg cgtctcgcgg cggggttggg ccacctggaa gttgatcaaa
     4681 cgcatcgcgt agagcccagt ctaccagaca ctggcgtgcg gtgtcacaag gtgagagttg
     4741 actagtaacg tcgtcgatga tggtgtcgga catgagggac gctccgtaat gaaggacctg
     4801 acatgacagc ccattcaatt gcgtcaccac gccacctgcg agcttgtcga aatacagctg
     4861 cttggtcaag gcctcggtgc agatggcttc tatcaagtgg tatgcatccg ggcagagaaa
     4921 tggagagccg gtgaatgggg atatcagtgg cacctgcaaa gcacgggtgc cccatttctc
     4981 ccagacctcc gccatctcaa ggatggcgcg gacgtcttcg tcgtcataca catttgggac
     5041 atggcagagg ccgcctgaga tgggcagcgc tgagtgcctt gaggaacgga gtagctcgga
     5101 ctggcggaag agctgcttga ggcggctggg agggcctgtg acgccaactg aggtttggtc
     5161 aacgtgactg atactcacgc cagtcagggg ccttgcattt gcaccagggc tttctgactc
     5221 ttttagatga ttgaaccggt ccaattccac ctggatggtg tctgccggca cgcctatgac
     5281 gaccgtggcc cagctaactg atgcagcctg ctctgtcatg gtaggttcga gttcttggga
     5341 aacgcgctgt acatgaacac agaatgcaaa cgcggtccgc acgctttcag ctccatacga
     5401 gacgaggtcc gatatggact tcgaaacagc tactgctgct gccgagaata gaccaacgct
     5461 gattcctacc aagcatgctg gacggcggta cgagagttga tgtgtctcat ggtgtctgag
     5521 taggaggccc atgttagctc acataaataa cgcgttaata ccggaatcag ggagtagttg
     5581 agaacctacc caatcagcat agctatctca tagaggcaga ggaaagggcc atcccaagcc
     5641 ccactcaaag ggccgctctt gagacgatcc cagtgagagg ccagcgtcac cacatcatgg
     5701 aatggcggga cagaatctcg cagtgcccgt gggagcttct gaatctccgt tcggagcaac
     5761 aaggcgcatt cctgtaagaa gcgagcgagg tgtggatagc caggtaacgt gccatatcta
     5821 tgcagtcgtc gtatcaggtc ttggatgtcg ccgctgggaa gctcgtgact gaatagaata
     5881 aaatcgttcg gtgaatcggc gtcaaccttg acatttgcat ccccggggtt tggtgatggg
     5941 gacggggatg cagacggagt catcgtggtg tattcgctag ttgtgcaagt ttcgcagatg
     6001 tctcccatct cgccacgaag cgaaggtgaa gaagacaatg ttgaatgaaa gagcaattct
     6061 aaatatattg aaaagacagt taaagaccgc gttgttcgat tttcatcagc gagcagatca
     6121 aaagcccgta gggtttctgt ggactattaa ccgcgggttc cataagaaca atatactcag
     6181 tgtcactgta caggaggttt acttctttat cctaacataa aaaggcactg ccactggctg
     6241 cgccaagtcc accttgtttc cagccccagc tggcttatac ttggcttagg gcagacgcag
     6301 taagcaggcg tgggacgccc tgcatggcgt cagcacaggt cggaatccga atcggcaggt
     6361 tacttaacgc agcggtgtag gcaatccgac gcaaattcag acatgaatga gcaggcagcc
     6421 ttgattcgaa aggggaatga gtgcggcata ataatgctgg acatgtatta ctattcctag
     6481 tcacagagac cgccccaaga acgctcccaa gaactacttt cggacaaggg cagattgcgg
     6541 caatcgaaat atgaagctct aaattacagg gattgaaaag aagcctggct tttgaaagat
     6601 aaccagaata gagacgtggt cacagcacta ccatgtttgt atgtgagatt agaccatcac
     6661 ttatacaaag taaaaagcaa gaatctctaa attgattgag ccgttgcgaa ccaatgtatc
     6721 ttgttatctg gcccaacaac tctcgaacca accttgcctt gctcaagcaa catgtacagc
     6781 acctggttca atagagggcc tacagccgag tcaaacgttg ggctattctt gacggactct
     6841 ccatagacaa gaccgccgat ctctgctgtt gagagaccct gcattgcagg tctactcgtt
     6901 ttcatgttat tatcctcctc gtcgctatca ccagactcgc tgacgctccc aatactgctc
     6961 gtgctgcccc cattgcgaga cgaacaagag caagcatgca gggccaagat ggcatatatc
     7021 ttcttttctc ttgcgactct ctgcgaaata tatcttgcaa tcgtttgcgg cagattgagt
     7081 atcgcgtctc cgtggccggg atatccaacg gaacacttga gccctgccat caggcggagg
     7141 ctggcagtgt aggtttccag gtcctcagca acactgtagc catggcctag cacattgtcg
     7201 ccggtgaaca gtgcgttctc ttcctccagc aagaagcaca tgtggtcgac agcatgccca
     7261 ggcgtcagga ccgctcttag agtggcacct tgtgttttga aagtctggcc attcgcaatg
     7321 gcctgctggc ccgggtcggg cgcatgcttg tacactatta tgctggggtc atgcgcaaga
     7381 aggtcggcta ctccgccggt atggtccttg tgccaatgcg tgagaaggac gtgggagatg
     7441 gagatgtcgt ggtcttcgag ataacgggtc acactgactg cccattgcgg agctccctgt
     7501 gaaatagttc aatattgatc ctcaagaagt ggtttttacg cagatggttt attctcagaa
     7561 aaccgaaagt agtatcacat cacccataaa cacatgaaca tcgaagaaca ctcaagggtg
     7621 atttgggtta aggtcttacc tctccagtgt cgatgagtat cctggtgctt ccagtaccga
     7681 ctaggtatgt gttggtgccc tgcagctgca tgctaccagg gttgtatcca agaaagcgca
     7741 cgacacagtg agacaagcca tcgtcgattt ctgggagcac aggtagcctg ctccgctgag
     7801 tctctagata gccagcccag aagggcgacg agtaaaatcc cccagacat
//
