BGC0000023: aurafuron A biosynthetic gene cluster from Stigmatella aurantiaca DW4/3-1
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Location: 1 - 58,500 nt. (total: 58,500 nt).
This entry is originally from NCBI GenBank AM850130.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000023
Short description aurafuron A biosynthetic gene cluster from Stigmatella aurantiaca DW4/3-1
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type I)
Loci
AM850130.1
via Knock-out studies
Compounds
  • aurafuron A
Species Stigmatella aurantiaca DW4/3-1 [taxonomy]
References
Chemical products information
aurafuron A Evidence:
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C22H34O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAO98841.1
 1 - 1350 (+) hypothetical protein
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    • CAO98842.1
    		 1384 - 2424 (-) hypothetical protein
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      • CAO98843.1
      		 2541 - 4415 (-) hypothetical protein
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        • CAO98844.1
        		 4952 - 5443 (+) hypothetical protein
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          • CAO98845.1
          • aufA
          		 5683 - 7113 (+) cytochrome P450 monooxygenase AufA
          • Tailoring
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          • CAO98846.1
          • aufB
          		 7260 - 8498 (+) cytochrome P450 monooxygenase AufB
          • Tailoring
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          • CAO98847.1
          • aufC
          		 8559 - 14162 (-) polyketide synthase AufC
          • Scaffold biosynthesis
          • Knock-out
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          • CAO98879.1
          • aufD
          		 14167 - 24348 (-) polyketide synthase AufD
          • Scaffold biosynthesis
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          • CAO98848.1
          • aufE
          		 24944 - 30439 (+) polyketide synthase AufE
          • Scaffold biosynthesis
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          • CAO98849.1
          • aufF
          		 30506 - 40588 (+) polyketide synthase AufF
          • Scaffold biosynthesis
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          • CAO98850.1
          • aufG
          		 40595 - 47005 (+) polyketide synthase AufG
          • Scaffold biosynthesis
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          • CAO98851.1
          • aufH
          		 46998 - 48407 (+) cytochrome P450 monooxygenase AufH
          • Tailoring
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          • CAO98852.1
          • aufI
          		 48404 - 56530 (+) polyketide synthase AufI
          • Scaffold biosynthesis
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          • CAO98853.1
          • aufJ
          		 56535 - 58055 (+) monooxygenase AufJ
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          Biosynthesis information

          Biosynthetic modules

          Name
          1
          Type
          pks-modular
          Genes
          aufI
          Substrates
          Integrated Monomers
          Domains
          acyltransferase, ketosynthase, acyltransferase, ketoreductase, dehydratase, enoylreductase, carrier (ACP)
          Name
          2
          Type
          pks-modular
          Genes
          aufD
          Substrates
          Integrated Monomers
          Domains
          acyltransferase, ketosynthase, acyltransferase, ketoreductase, carrier (ACP)
          Name
          3
          Type
          pks-modular
          Genes
          aufD
          Substrates
          Integrated Monomers
          Domains
          acyltransferase, ketosynthase, acyltransferase, ketoreductase, carrier (ACP)
          Name
          4
          Type
          pks-modular
          Genes
          aufF
          Substrates
          Integrated Monomers
          Domains
          acyltransferase, ketosynthase, acyltransferase, ketoreductase, dehydratase, carrier (ACP)
          Name
          5
          Type
          pks-modular
          Genes
          aufF
          Substrates
          Integrated Monomers
          Domains
          acyltransferase, ketosynthase, acyltransferase, ketoreductase, carrier (ACP)
          Name
          6
          Type
          pks-modular
          Genes
          aufC
          Substrates
          Integrated Monomers
          Domains
          acyltransferase, ketosynthase, acyltransferase, ketoreductase, dehydratase, carrier (ACP)
          Name
          7
          Type
          pks-modular
          Genes
          aufE
          Substrates
          Integrated Monomers
          Domains
          acyltransferase, ketosynthase, acyltransferase, ketoreductase, enoylreductase, carrier (ACP)
          Name
          8
          Type
          pks-modular
          Genes
          aufG
          Substrates
          Integrated Monomers
          Domains
          acyltransferase, ketosynthase, acyltransferase, dehydratase, enoylreductase, carrier (ACP)
          Annotation changelog

          Entry version: 4

          Date
          Changes
          Submitters
          Reviewers
          2022-10-07
          Update chemical activity to schema version 2.11
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          2022-09-15
          Removed ketoreductase stereochemistry annotation from modules without ketoreductases
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Sorted modules by module number
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Updated bioactivity data
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          2019-10-16
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2019-10-16
          Updated compound(s) information (NPAtlas curation)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          2015-06-12
          Submitted
          • (ID: 7SR74ARK6JXRBGJRGO2LUHE7)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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