LOCUS       BGC0000030             18435 bp    DNA     linear   PLN 12-JAN-2016
DEFINITION  Fusarium fujikuroi IMI 58289 draft genome, chromosome FFUJ_chr05.
ACCESSION   BGC0000030
VERSION     BGC0000030
KEYWORDS    .
SOURCE      Fusarium fujikuroi IMI 58289
  ORGANISM  Fusarium fujikuroi IMI 58289
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
            Fusarium; Fusarium fujikuroi species complex.
COMMENT     Sequencing was performed by Eurofins MWG Operon, Germany Guldener
            U., Wiemann P., Sieber C., Munsterkotter M., Tudzynski B.
            Westfaelische Wilhelms-Universitaet Muenster
            Institut fuer Biologie und Biotechnologie der Pflanzen,
            Schlossplatz 8, 48143 Muenster, Germany
            tudzynsb@uni-muenster.de.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 12:35:27
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 100852
            Orig. end    :: 119287
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     exon            complement(1..702)
                     /locus_tag="FFUJ_14916"
                     /number=2
     gene            complement(1..1084)
                     /locus_tag="FFUJ_14916"
     CDS             complement(join(1..702,755..1084))
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FFUJ_14916"
                     /db_xref="EnsemblGenomes-Tr:CCT69238"
                     /db_xref="GOA:S0E9S7"
                     /db_xref="InterPro:IPR013094"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/TrEMBL:S0E9S7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066:alpha/beta hydrolase domain-containing protein
                     (Score: 160.6; E-value: 8.1e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="FFUJ_14916"
                     /product="uncharacterized protein"
                     /protein_id="CCT69238.1"
                     /transl_table=11
                     /translation="MTTEQSRVSIPTVTDGQEWPFPYRIYLNCVTWTLRKLVSFLTGPN
                     EGHDREVKISTPGLGAGYVICNVWLPKPTDDIQSKYPLVLVLEGGGFVLGHPKDGRLNN
                     RQIVDQTGAIVMSVDYAKAPRYPYPHALLQAYEALRWALTSSAACEGIHVDPSRVAIGG
                     NSAGGNLTAALSLLLSFRSGPCSIFRERLPLDFKQVLHFMFYPSLELCLPYDLRLSRST
                     IDAQKYSLPAWMARAMEQSYLPPRVCKDDIFISPVAAGLDLLRELDIPPAVMFTGSLDC
                     LKEEGFCYAQHLTKSGKEVTFHEFQGVTHGFSVKPQDGSMEAQVMYEECWSRICHCLRE
                     SFS"
     subregion       1..18435
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..18435
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     intron          complement(703..754)
                     /locus_tag="FFUJ_14916"
                     /number=1
     exon            complement(755..1084)
                     /locus_tag="FFUJ_14916"
                     /number=1
     exon            complement(1350..3455)
                     /locus_tag="FFUJ_06742"
                     /number=4
     gene            complement(1350..7620)
                     /locus_tag="FFUJ_06742"
     CDS             complement(join(1350..3455,3511..6942,6998..7283,
                     7334..7620))
                     /NRPS_PKS="Domain: SAT (7-242). E-value: 7.6e-72. Score:
                     233.6. Matches aSDomain: nrpspksdomains_FFUJ_06742_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (372-801). E-value:
                     1.2e-146. Score: 480.8. Matches aSDomain:
                     nrpspksdomains_FFUJ_06742_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (908-1206). E-value: 2e-80.
                     Score: 262.2. Matches aSDomain:
                     nrpspksdomains_FFUJ_06742_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1289-1605). E-value: 4.8e-102.
                     Score: 333.4. Matches aSDomain:
                     nrpspksdomains_FFUJ_06742_PT.1"
                     /NRPS_PKS="Domain: ACP (1661-1728). E-value: 5.3e-18.
                     Score: 57.0. Matches aSDomain:
                     nrpspksdomains_FFUJ_06742_ACP.1"
                     /NRPS_PKS="Domain: Thioesterase (1785-1940). E-value:
                     4.6e-29. Score: 94.3. Matches aSDomain:
                     nrpspksdomains_FFUJ_06742_Thioesterase.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FFUJ_06742"
                     /db_xref="EnsemblGenomes-Tr:CCT67991"
                     /db_xref="GOA:S0DZM7"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="InterPro:IPR030918"
                     /db_xref="InterPro:IPR032088"
                     /db_xref="UniProtKB/TrEMBL:S0DZM7"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 148.1; E-value: 6.8e-45)"
                     /gene_kind="biosynthetic"
                     /locus_tag="FFUJ_06742"
                     /product="bikaverin cluster-polyketide synthase"
                     /protein_id="CCT67991.1"
                     /sec_met_domain="itr_KS (E-value: 5.3e-160, bitscore:
                     521.6, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.5e-81, bitscore: 262.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-15, bitscore:
                     46.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASSADVYVFGDQSTPVLDKLQALVRVKDNALLTSFLGEAFLAVR
                     REIVSLSSLERKSIPEAESLSLLLEGVRRSEPHAALDSAFVCIYEIGYYIDYLARSDKQ
                     HPPAAPSLLLGICTGSIAAAAVSCAKDVFEISRLGVEAATVAFRLGMHVRRRAENLGYS
                     TPSSWSMILSSNQEELVSEALKEFSKEKNLTYSSRPYISATGPGFTTISGPPSILESVK
                     SCDTFSGKRLYPAPIYGPYHNSSSYSESSLEHGLASILEDVGFLENEMLIPIISCASGS
                     RLDQLSFGNLLKNVLSSALSQQIRMDLVTDALVETVSGTEATLIPVNAQTTVCSLADWL
                     AKRGATTRIGPTLESLTKDRAEPNLAPGDENKIAIIGFSGRFPEADNLDEFWDLLIRGL
                     DVHKPVPEERFARDHYDPTGQRKNTSQVQYGCWLKSAGYFDTQFFHMSPKEAMQTDPAQ
                     RLALLTAYEALEMAGVVPDRTPSTQRNRVGVYYGTTSNDWGEVNSSQDVDTYYIPGANR
                     AFIPGRVNYFFKFTGPSIAVDTACSSSLAAINLAITSLKNRDCDTAIAGGTNVMTNPDN
                     FAGLDRGHFLSRTGNCKAFDDGADGYCRADGIGTLILKRLPDAIADSDPIFGVILGAHT
                     NHSAESVSITRPLADAQEYLFKKLLNETGIHPHDVSYVEMHGTGTQAGDAVEMRSVLNS
                     FAFDHSRPRDKSLYLGSVKANVGHAESASGVLAIIKVLLMMQKNTIPPHCGIKTKINQG
                     FPKDLDHRGVRIALKDSVDWSRPEGGKRRVLVNNFSAAGGNTSLLLEDGPAVHPARQHQ
                     DGDARTEHVVAVSARSTKALEENLKALEAYIANSWAPEGELLSQLSYTTTARRVHHSRR
                     VAFVTNGLDDLRKSLLKAATDAGQVKGIPAVSPKVGFLFTGQGAQETAMAIGYYKSFSS
                     FRSDIHQLDSIATLQGLPSVLPLIHGTTPVEDLSAVVVQLGTCIIQISLARFWISLGIT
                     PQYVIGHSLGEYAALQIAGVLSVNDAIFLCGHRAALLDKKCTAYTHGMVAVKAAADDLR
                     QHISSDLKVEIACVNGAEDTVLSGPNADIESLCGKLTQAGYKLHKLEIPFAFHSSQVDP
                     ILDDLEELASQVGFHEPKLPIVSPLLRTLLTGDTLGPQYIRRHCRETVDFLGAIKMAES
                     QGIMDRSGMCIEIGAHPILTRMVKSIIGQDFRCLASLRRKEDHFKTLADSLCALHLAGF
                     SVNWDEYHRDFASSRNVLQLPKYSWQLANYWMQYKYSWCLTKGDAPVENGPVGAVVQAR
                     ALRLSDSVHNVIEQVHGDKRSSITVESDMHDPSLLAIAQNHRVNGLTMAPSTLFADIAF
                     TLAKHLIQNHGLDTHTNLPSINNMAVEKALIVGETGPQLFRASLDMDWTTMRGSVRIFS
                     VGANGKQTTLHAVCDVAVENPSSHRESWQSNAYLIQRGIKQLVQGASDGSAHMMRRGLL
                     YKIFSNSVQYGSAFQGIEQVWFDSEGLEGTGKVFMPSGKDTFALNPYCCDSLGHITGFI
                     MNCSDSLDLDDHVYINHGWRTLRLVEPYQCDVQYQTYVKMQAVGSDDSTYSGDVHVLRD
                     GKIIGICGGVTFKKVARKVLEMLLPKPSGAKAKHGVVKHVAPEPVKHVVLTPPSTTSHS
                     VGTTSPPEPTESPVGSASGLIQKALEIIADEIGVDISQLTDTTLLADLGVDSLMSLTIL
                     GNFREELDLDIPAAQFYEFSTVQDLKSFLGANDQDFSSSNSEAESSASSAASTSPSDHG
                     DDVVEEVKPVVAEIPRSTSTILQGTKHCSQTLFLFPDGAGSATSYVTLPSISSDMRVIG
                     LNSPYLTKPHEFNCALQDITGSYLNEVRRRQPQGPYHLAGWSAGGVSAFDAARQLVSEG
                     EVVESLILIDSPNPVGLGKLPKRMYDFLEKSGIFGAFEMGEEAQAPPDWLFQHFCVFIE
                     ALDRYVPEPFEHGMAPKTTIIWAADGVCKNPDDPRPEAQPDDPRGMNWLLNNREDFGPN
                     GWDEFIGAGNISTMAIENANHFTMMREPIASALCAKIRETMGVN"
     aSDomain        complement(1641..2105)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FFUJ_06742_Thioesterase.1"
                     /evalue="4.60E-29"
                     /label="FFUJ_06742_Thioesterase.1"
                     /locus_tag="FFUJ_06742"
                     /protein_end="1940"
                     /protein_start="1785"
                     /score="94.3"
                     /tool="antismash"
                     /translation="QTLFLFPDGAGSATSYVTLPSISSDMRVIGLNSPYLTKPHEFNCA
                     LQDITGSYLNEVRRRQPQGPYHLAGWSAGGVSAFDAARQLVSEGEVVESLILIDSPNPV
                     GLGKLPKRMYDFLEKSGIFGAFEMGEEAQAPPDWLFQHFCVFIEALDRYVP"
     aSModule        complement(1641..6399)
                     /complete
                     /domains="nrpspksdomains_FFUJ_06742_PKS_KS.1"
                     /domains="nrpspksdomains_FFUJ_06742_PKS_AT.1"
                     /domains="nrpspksdomains_FFUJ_06742_PT.1"
                     /domains="nrpspksdomains_FFUJ_06742_ACP.1"
                     /domains="nrpspksdomains_FFUJ_06742_Thioesterase.1"
                     /final_module
                     /iterative
                     /locus_tags="FFUJ_06742"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(1851..1925)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0009"
                     /evalue="1.80E-13"
                     /label="NRPS-te1"
                     /locus_tag="FFUJ_06742"
                     /protein_end="1870"
                     /protein_start="1845"
                     /score="42.8"
                     /tool="antismash"
                     /translation="QPQGPYHLAGWSAGGVSAFDAARQL"
     aSDomain        complement(2277..2477)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FFUJ_06742_ACP.1"
                     /evalue="5.30E-18"
                     /label="FFUJ_06742_ACP.1"
                     /locus_tag="FFUJ_06742"
                     /protein_end="1728"
                     /protein_start="1661"
                     /score="57.0"
                     /tool="antismash"
                     /translation="ALEIIADEIGVDISQLTDTTLLADLGVDSLMSLTILGNFREELDL
                     DIPAAQFYEFSTVQDLKSFLGA"
     aSDomain        complement(join(2646..3455,3511..3648))
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FFUJ_06742_PT.1"
                     /evalue="4.80E-102"
                     /label="FFUJ_06742_PT.1"
                     /locus_tag="FFUJ_06742"
                     /protein_end="1605"
                     /protein_start="1289"
                     /score="333.4"
                     /tool="antismash"
                     /translation="DSVHNVIEQVHGDKRSSITVESDMHDPSLLAIAQNHRVNGLTMAP
                     STLFADIAFTLAKHLIQNHGLDTHTNLPSINNMAVEKALIVGETGPQLFRASLDMDWTT
                     MRGSVRIFSVGANGKQTTLHAVCDVAVENPSSHRESWQSNAYLIQRGIKQLVQGASDGS
                     AHMMRRGLLYKIFSNSVQYGSAFQGIEQVWFDSEGLEGTGKVFMPSGKDTFALNPYCCD
                     SLGHITGFIMNCSDSLDLDDHVYINHGWRTLRLVEPYQCDVQYQTYVKMQAVGSDDSTY
                     SGDVHVLRDGKIIGICGGVTFKKVARKVLEMLLPK"
     intron          complement(3456..3510)
                     /locus_tag="FFUJ_06742"
                     /number=3
     exon            complement(3511..6942)
                     /locus_tag="FFUJ_06742"
                     /number=3
     CDS_motif       complement(3631..3693)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0008"
                     /evalue="1.10E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="FFUJ_06742"
                     /protein_end="1295"
                     /protein_start="1274"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="GPVGAVVQARALRLSDSVHNV"
     aSDomain        complement(3898..4791)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FFUJ_06742_PKS_AT.1"
                     /evalue="2.00E-80"
                     /label="FFUJ_06742_PKS_AT.1"
                     /locus_tag="FFUJ_06742"
                     /protein_end="1206"
                     /protein_start="908"
                     /score="262.2"
                     /tool="antismash"
                     /translation="LFTGQGAQETAMAIGYYKSFSSFRSDIHQLDSIATLQGLPSVLPL
                     IHGTTPVEDLSAVVVQLGTCIIQISLARFWISLGITPQYVIGHSLGEYAALQIAGVLSV
                     NDAIFLCGHRAALLDKKCTAYTHGMVAVKAAADDLRQHISSDLKVEIACVNGAEDTVLS
                     GPNADIESLCGKLTQAGYKLHKLEIPFAFHSSQVDPILDDLEELASQVGFHEPKLPIVS
                     PLLRTLLTGDTLGPQYIRRHCRETVDFLGAIKMAESQGIMDRSGMCIEIGAHPILTRMV
                     KSIIGQDFRCLASLRRK"
     CDS_motif       complement(4438..4557)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0007"
                     /evalue="6.40E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="FFUJ_06742"
                     /protein_end="1026"
                     /protein_start="986"
                     /score="50.4"
                     /tool="antismash"
                     /translation="GITPQYVIGHSLGEYAALQIAGVLSVNDAIFLCGHRAALL"
     aSDomain        complement(5113..6399)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FFUJ_06742_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.20E-146"
                     /label="FFUJ_06742_PKS_KS.1"
                     /locus_tag="FFUJ_06742"
                     /protein_end="801"
                     /protein_start="372"
                     /score="480.8"
                     /tool="antismash"
                     /translation="IAIIGFSGRFPEADNLDEFWDLLIRGLDVHKPVPEERFARDHYDP
                     TGQRKNTSQVQYGCWLKSAGYFDTQFFHMSPKEAMQTDPAQRLALLTAYEALEMAGVVP
                     DRTPSTQRNRVGVYYGTTSNDWGEVNSSQDVDTYYIPGANRAFIPGRVNYFFKFTGPSI
                     AVDTACSSSLAAINLAITSLKNRDCDTAIAGGTNVMTNPDNFAGLDRGHFLSRTGNCKA
                     FDDGADGYCRADGIGTLILKRLPDAIADSDPIFGVILGAHTNHSAESVSITRPLADAQE
                     YLFKKLLNETGIHPHDVSYVEMHGTGTQAGDAVEMRSVLNSFAFDHSRPRDKSLYLGSV
                     KANVGHAESASGVLAIIKVLLMMQKNTIPPHCGIKTKINQGFPKDLDHRGVRIALKDSV
                     DWSRPEGGKRRVLVNNFSAAGGNTSLLLED"
     CDS_motif       complement(5344..5388)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0006"
                     /evalue="2.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="FFUJ_06742"
                     /protein_end="724"
                     /protein_start="709"
                     /score="10.5"
                     /tool="antismash"
                     /translation="GSVKANVGHAESASG"
     CDS_motif       complement(5455..5502)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0005"
                     /evalue="4.80E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="FFUJ_06742"
                     /protein_end="687"
                     /protein_start="671"
                     /score="12.4"
                     /tool="antismash"
                     /translation="YVEMHGTGTQAGDAVE"
     CDS_motif       complement(5695..5733)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0004"
                     /evalue="3.40E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="FFUJ_06742"
                     /protein_end="607"
                     /protein_start="594"
                     /score="10.7"
                     /tool="antismash"
                     /translation="FDDGADGYCRADG"
     CDS_motif       complement(5875..5922)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0003"
                     /evalue="3.50E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="FFUJ_06742"
                     /protein_end="547"
                     /protein_start="531"
                     /score="19.0"
                     /tool="antismash"
                     /translation="GPSIAVDTACSSSLAA"
     aSDomain        complement(join(6790..6942,6998..7283,7334..7599))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FFUJ_06742_SAT.1"
                     /evalue="7.60E-72"
                     /label="FFUJ_06742_SAT.1"
                     /locus_tag="FFUJ_06742"
                     /protein_end="242"
                     /protein_start="7"
                     /score="233.6"
                     /tool="antismash"
                     /translation="YVFGDQSTPVLDKLQALVRVKDNALLTSFLGEAFLAVRREIVSLS
                     SLERKSIPEAESLSLLLEGVRRSEPHAALDSAFVCIYEIGYYIDYLARSDKQHPPAAPS
                     LLLGICTGSIAAAAVSCAKDVFEISRLGVEAATVAFRLGMHVRRRAENLGYSTPSSWSM
                     ILSSNQEELVSEALKEFSKEKNLTYSSRPYISATGPGFTTISGPPSILESVKSCDTFSG
                     KRLYPAPIYGPYH"
     intron          complement(6943..6997)
                     /locus_tag="FFUJ_06742"
                     /number=2
     exon            complement(6998..7283)
                     /locus_tag="FFUJ_06742"
                     /number=2
     CDS_motif       complement(7184..7246)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0002"
                     /evalue="1.60E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="FFUJ_06742"
                     /protein_end="129"
                     /protein_start="108"
                     /score="2.0"
                     /tool="antismash"
                     /translation="APSLLLGICTGSIAAAAVSCA"
     intron          complement(7284..7333)
                     /locus_tag="FFUJ_06742"
                     /number=1
     exon            complement(7334..7620)
                     /locus_tag="FFUJ_06742"
                     /number=1
     CDS_motif       complement(7585..7611)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FFUJ_06742_0001"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="FFUJ_06742"
                     /protein_end="12"
                     /protein_start="3"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="SADVYVFGD"
     exon            complement(8353..9266)
                     /locus_tag="FFUJ_06743"
                     /number=3
     gene            complement(8353..9930)
                     /locus_tag="FFUJ_06743"
     CDS             complement(join(8353..9266,9319..9572,9629..9930))
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FFUJ_06743"
                     /db_xref="EnsemblGenomes-Tr:CCT67992"
                     /db_xref="GOA:S0E2X6"
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR023753"
                     /db_xref="UniProtKB/TrEMBL:S0E2X6"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 220.1; E-value: 9.5e-67)"
                     /gene_kind="other"
                     /locus_tag="FFUJ_06743"
                     /product="bikaverin cluster-monooxygenase"
                     /protein_id="CCT67992.1"
                     /transl_table=11
                     /translation="MAEPNQHYEVIIAGGGIAGVTLALMFEKLDISYFLLEGRDTLESD
                     RGAGIGLQPNGLRILDQLGLVEDIEEATIPLEKWFSYDSEGNLMNDSDAMGQYRDKIGY
                     PVAFIERRKLLPIMVRHIQRTECVKTSARVASIEESEDHVTVTTTDGLSLTADIVVGAD
                     GVRSAVRTHIDSKLPEPLTADDYISVACSTVYGMSAPTEGIAPGERFAVYRENQTVIGF
                     TGKDGIVFWFVFENLNRNVPLSQAPRYTEAEAEALCLSVAHTQVTPKLKFGEIYKNSVV
                     AVKIGVEEGVAKGWHTDRAVIVGDAACKTTPAGGQGANQAIESCAVFVNKLMAARKASQ
                     SGDKLSSDVVKSVLASYAQERAQPATTALERSQMVGKALLCTPGPATTLVKDMLKLSNE
                     DWLLRAFMALSAAPYLEDVELTARGHLYNKAVEEARAEMARRQRVAKEVKEAEEKESKQ
                     AASIKESEQRNEFVGLRNPVQAATGVVEVGS"
     intron          complement(9267..9318)
                     /locus_tag="FFUJ_06743"
                     /number=2
     exon            complement(9319..9572)
                     /locus_tag="FFUJ_06743"
                     /number=2
     intron          complement(9573..9628)
                     /locus_tag="FFUJ_06743"
                     /number=1
     exon            complement(9629..9930)
                     /locus_tag="FFUJ_06743"
                     /number=1
     exon            10332..10658
                     /locus_tag="FFUJ_06744"
                     /number=1
     gene            10332..11795
                     /locus_tag="FFUJ_06744"
     CDS             join(10332..10658,10709..11221,11274..11795)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FFUJ_06744"
                     /db_xref="EnsemblGenomes-Tr:CCT67993"
                     /db_xref="GOA:S0E608"
                     /db_xref="InterPro:IPR001077"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR016461"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:S0E608"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 259.2; E-value:
                     9.5e-79)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="FFUJ_06744"
                     /product="bikaverin cluster-O-methyltransferase"
                     /protein_id="CCT67993.1"
                     /transl_table=11
                     /translation="MVSNGISNGTNGTNGTTTNGTNGVNGHAALSPLEVLVQDLNKNTT
                     TLNGYLRANKLPEPSFERDAPIINLSPDAPEEAQVAKEKVLDSALQIFQLVSGPGEYLQ
                     NVITGYHYMEILRWMSHFKIFELVPLEGKISYTELASKAGVAELRLKTLARMGMTNHLF
                     AEPEPGFIAHSATSAALVTNNRFSDQRVWMTSIIAPVIASMVTAHERWPDSTAPNKAAF
                     NAAFNTDLRMYEYISKQPDVYKLFGRVMDAIATSPKSDLKHLVSGFDWAGLGKANVVDI
                     GGNIGHSCVKLAEAFPDLNFIIQDIPHVVEEGAKVIKENNEASIANRIQFQEYDFFQKQ
                     PVVGADIYLLRQIFHNWDFENSVKILKNTVESMGQNSHVLIMDFVVPEPGTVSSVNERV
                     LRSRDVGMMQLFNSLERDLEGWKAILEAVDSRLKINAVNTPYGSFMSVIDVVLG"
     intron          10659..10708
                     /locus_tag="FFUJ_06744"
                     /number=1
     exon            10709..11221
                     /locus_tag="FFUJ_06744"
                     /number=2
     intron          11222..11273
                     /locus_tag="FFUJ_06744"
                     /number=2
     exon            11274..11795
                     /locus_tag="FFUJ_06744"
                     /number=3
     gene            12567..13547
                     /locus_tag="FFUJ_06745"
     CDS             12567..13547
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FFUJ_06745"
                     /db_xref="EnsemblGenomes-Tr:CCT67994"
                     /db_xref="InterPro:IPR008030"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:S0DZI6"
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 133.7; E-value: 1.5e-40)"
                     /gene_kind="other"
                     /locus_tag="FFUJ_06745"
                     /product="bikaverin cluster-transcription factor enhancer"
                     /protein_id="CCT67994.1"
                     /transl_table=11
                     /translation="MPSPHFSKVLVFGATGEVGSAVALEAHALGAHVSIALRDTTKHNE
                     WISPSQEHAADLQRISADLTDPDSLKRAVHDTGAQAAFIYAVRSKDTLRGAITALRDAG
                     IQYLVFLSTSQVRTAGTTKGDIRSIKPDHFIPWQHAQVEIALEELEVPHAAVRAGFFAS
                     NPLRIYLDRSSEPKQVNLLAPEVPHDPIDPKDIGRAAAAVLVNPRLYASGYQGEPKKDV
                     VYLSGPALLSQTEQWEIINRELVAAGKPEVKVNHITVEQYLENLAKLHVPDVVAKSLAK
                     SMVETRALYAPEDYEKSRGNVELLTGRKATAFDEFVKREIPRYFD"
     exon            complement(13737..15581)
                     /locus_tag="FFUJ_06746"
                     /number=3
     gene            complement(13737..16100)
                     /locus_tag="FFUJ_06746"
     CDS             complement(join(13737..15581,15656..15777,15836..16100))
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FFUJ_06746"
                     /db_xref="EnsemblGenomes-Tr:CCT67995"
                     /db_xref="GOA:S0E028"
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR007219"
                     /db_xref="UniProtKB/TrEMBL:S0E028"
                     /locus_tag="FFUJ_06746"
                     /product="bikaverin cluster-transcription factor"
                     /protein_id="CCT67995.1"
                     /transl_table=11
                     /translation="MDSALGNLSMPGLAQSHVQVRTCIHCRQRRVKCDRQFPQCSNCIR
                     SEVNCIYPPGRGRAPKRPKRSLAPQLSERLSRLESIIGQFGAAARENQDTPQTAQDSEG
                     HSFEQDFSRLKVDESKSYYVNNALWVEELRDLLFEPASEDAGYEPSISSSATTAATSPS
                     SPQLGLNAAIFGYRAIASPLYHYHPSLQQAVTLFAAFSENVAPLVRIFHMPTLTRIYWD
                     AIASLGTVDKHTETLLFTIHYSAVISLNPEQCLNILDETREAALERYRFAVEQALAQGN
                     LLSTQSMTMLQAAVLFLSALPNEDDSRAAWALTSLVFHIARTMGLHRDGTIFGLKPFET
                     ELRRRLWWQICIIDSRSSEYHCNEPIAQGFITDTKPPLHINDVDLSPEMVEPPAERWDH
                     ATDMTLTLVRCEAIQTGLKLGRMRHKQNKTSEDGSTPRVDDTSDTPKTLIQELESRLRD
                     KYLPICDTSVPFQLLSSAVAQIILGRFWLITQYSVVSREREVDGKSTSNQFPPTPNTAG
                     QLDNKVRDELFQTSIKILEVSGMLLTSKEIIQFTWYSKTHIQWGAMAFVLSELCARPQS
                     AQCDQAWDCVTTVYEGWKVDESKQDETRLALWRPIKRLMAKARYVKEMQQTTPGRSSNA
                     GRKVQRRDPVLYSPSPGLFSQYPTPAYSNNWYGPLQQTPPSIPGSEASLPGMATVPLDS
                     SGQSDALQRVLGTETLGPFMDMIPEWPWVDAEHGASSLAGFDLGLPRFN"
     intron          complement(15582..15655)
                     /locus_tag="FFUJ_06746"
                     /number=2
     exon            complement(15656..15777)
                     /locus_tag="FFUJ_06746"
                     /number=2
     intron          complement(15778..15835)
                     /locus_tag="FFUJ_06746"
                     /number=1
     exon            complement(15836..16100)
                     /locus_tag="FFUJ_06746"
                     /number=1
     exon            16610..16948
                     /locus_tag="FFUJ_06747"
                     /number=1
     gene            16610..18435
                     /locus_tag="FFUJ_06747"
     CDS             join(16610..16948,17010..17411,17512..17629,17731..17985,
                     18092..18435)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FFUJ_06747"
                     /db_xref="EnsemblGenomes-Tr:CCT67996"
                     /db_xref="GOA:S0DZN4"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:S0DZN4"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 64.2; E-value:
                     1.2e-19)"
                     /gene_kind="transport"
                     /locus_tag="FFUJ_06747"
                     /product="bikaverin cluster-efflux pump"
                     /protein_id="CCT67996.1"
                     /transl_table=11
                     /translation="MNEESNMGGVFKEEEAQSGDVVDFEGDSDTHNPQNWPMGKKVYTT
                     ALWALTTCWITFASAIYSAGTAEISEEFHVSYEVANAGTSLLIFGFALGPMLWAPLCEV
                     YGRKWPALAPYFISAAFAFGTATAKDIQTILITRFFAGVFGSSPISITGGSIVDIWTPR
                     QRGTPMVCYGITIAAAPTLGPIIGGAFIASGCGWRWTEYLTGIVMMVQFVLDALWLDES
                     HADVLLTRKASRLRRSTGNFSLHAKWEETSPTFKSLLSTYLVRPFQMLLDPICLLLTIY
                     TSFVYAILYASLESFALEYGRFRRWGPVVSQLPFLSLLIGCLFAAAANIFNNIYYGKKL
                     VANNFKPVPEARLPPMMVGGFAFSAGLFLFGWTSVEHVSSPWPSIIGVFLTGVGFTTIF
                     QSSLQYLVDTFTRYSASAIAANTFVRSMAAGAFPLFVWPMYEKIGIDWGSTIFACISVL
                     LLPAPFLFFKWGYRIRARGEFSKLSTY"
     intron          16949..17009
                     /locus_tag="FFUJ_06747"
                     /number=1
     exon            17010..17411
                     /locus_tag="FFUJ_06747"
                     /number=2
     intron          17412..17511
                     /locus_tag="FFUJ_06747"
                     /number=2
     exon            17512..17629
                     /locus_tag="FFUJ_06747"
                     /number=3
     intron          17630..17730
                     /locus_tag="FFUJ_06747"
                     /number=3
     exon            17731..17985
                     /locus_tag="FFUJ_06747"
                     /number=4
     intron          17986..18091
                     /locus_tag="FFUJ_06747"
                     /number=4
     exon            18092..18435
                     /locus_tag="FFUJ_06747"
                     /number=5
ORIGIN
        1 ctatgagaac gactctcgaa gacagtgaca tattctggac caacattcct cgtacatgac
       61 ctgcgcctcc atgctcccat cctgcggttt aactgagaat ccgtgagtaa caccttggaa
      121 ctcatggaaa gtgacttcct tgccgctttt cgtgagatgc tgcgcataac agaaaccttc
      181 ctctttgagg caatcgaggc taccggtgaa cattacagca ggtggaatat ccagctcacg
      241 gagcaggtct aatccagcag cgacgggaga tataaagatg tcgtctttgc agactcttgg
      301 cggcagatat gactgctcca ttgctctggc catccaagcg ggtaggctgt atttctgggc
      361 atcaatcgta gacctggaga gtcttagatc gtacggtaag caaagctcaa ggctgggata
      421 aaacatgaag tgcaggactt gtttgaagtc cagtggtaga cgttccctaa atatagagca
      481 aggaccgctt cgaaaggaca gtaacagaga taatgctgct gttaaatttc cacccgcaga
      541 gtttcctcca atcgccacac gtgaaggatc aacatggatg ccttcgcagg cagctgagga
      601 tgtaagagcc caacgcagcg cttcataagc ttgcagcaga gcgtgagggt aagggtatcg
      661 gggcgctttg gcgtaatcaa ccgacatgac aattgctccg gtctgcactg atattagctg
      721 cgagcgatcg ctgagcgtat cttgggctgc atacctgatc aacaatttga cgattattta
      781 ggcgtccgtc ctttggatgt cccaagacaa aaccaccgcc ttctagaact aacaccagtg
      841 gatacttgga ttggatatcg tctgtaggtt tgggtagcca tacattgcat ataacatagc
      901 ccgctcccaa acctggggta ctgatcttga cttctcggtc atgaccttca tttggaccgg
      961 tcagaaatga tacaagcttg cgcagagtcc aggtgacgca gttgaggtag attcgatagg
     1021 gaaagggcca ttcttggcca tctgttacag taggtatact aacacgactc tgctcagttg
     1081 tcatactgtg aggagaatta aaacagatcc ggattgatga gttaccaggt gtgaaagcgc
     1141 agtaaatgta gtgaaagtgg gctggcgctg gcgctaactt atgtcagtgc gctgacacag
     1201 tcaataacta acctatgcgg gtgagatgtg tacccgaggg agaacatgaa ttcaattaag
     1261 acggacaagt tcaagatatg agaatagcaa ttataggaaa tatgaataaa aatctaagtc
     1321 agagaaattt tgctgcttca acttccttgt caatttacgc ccattgtctc ccggatcttc
     1381 gcacagagag ccgacgcaat tggctccctc atcatagtaa agtggttggc attctcaatc
     1441 gccattgtgc tgatgtttcc cgcgccaatg aactcatccc aaccattcgg cccaaagtcc
     1501 tccctgttat tcaagagcca gttcattccc cgagggtcgt caggctgtgc ctcaggacgg
     1561 ggatcatcag ggttcttgca cacgccgtct gcagcccaga tgatggtcgt cttaggcgcc
     1621 ataccatgct caaacggttc aggcacgtac ctatccaaag cctcgatgaa gacacagaag
     1681 tgctggaaga gccagtcagg cggcgcttga gcttcctctc ccatctcgaa agcgccgaag
     1741 atacccgact tttcgaggaa gtcgtacata cgctttggca gcttgccaag accaaccggg
     1801 ttgggggagt caatcaggat gaggctctcg actacctctc cctctgatac aagctgacga
     1861 gcggcgtcga aggccgagac gcctcctgct gaccaacctg caagatggta agggccttga
     1921 ggttgacgtc gacgcacttc gttcaagtaa gagcctgtga tgtcctggag agcacagttg
     1981 aactcatgcg gcttggtaag gtaaggactg ttcaatccaa tgaccctcat gtcggacgaa
     2041 atagaaggga gagtgacata agacgttgct gaaccagcac cgtcggggaa cagaaagagt
     2101 gtttgagaac agtgcttggt gccctgcaag atcgtagagg ttgaccgagg tatctcagcc
     2161 actacaggct tgacctcctc aacgacatca tcaccgtgat cactagggga tgttgaagca
     2221 gcgctagacg cagaactctc cgcctcagag tttgagcttg agaagtcttg gtcattggct
     2281 ccaaggaagg acttgagatc ctgaactgtt gagaactcgt agaactgggc tgctggaatg
     2341 tccaagtcga gttcctctcg gaagttgccc agaatggtca gtgacatgag cgaatcaaca
     2401 cccaggtcag ccaagagtgt agtgtcagtg agctgagaga tgtcgactcc aatctcatcg
     2461 gcaatgatct cgagagcctt ctgaataagg ccagaagcag agccgacagg cgactctgtt
     2521 ggctcgggag gtgatgttgt gccgacgcta tggctagtgg tagacggggg agtgagaaca
     2581 acgtgtttga cgggctcggg agcaacgtgc ttaacaacgc catgcttggc tttggctccg
     2641 gaaggcttgg gtagaagcat ctcgagtacc ttgcgagcga ccttcttgaa cgtgacacca
     2701 ccacagatac cgataatctt accatcacga agaacgtgga catcgccact ataagtcgaa
     2761 tcatcagagc ctaccgcctg catcttgacg tatgtctgat actgcacgtc acactggtaa
     2821 ggttcaacca agcgaagcgt gcgccagcca tgattgatgt agacatgatc atcaagatcc
     2881 aagctatcac tgcagttcat gatgaagcca gtgatgtgac ccagactgtc acagcagtac
     2941 gggttgagcg cgaaagtgtc tttgcctgag ggcataaaga ccttgccagt tccttcgagt
     3001 ccttcactgt caaaccagac ctgctcgatg ccttggaacg cagacccgta ctggaccgag
     3061 ttggagaata tcttgtacaa gagaccacga cgcatcatgt gagcagaacc atcactggcg
     3121 ccttggacga gctgtttgat gcctcgctgg atgaggtacg cgttactctg ccagctttca
     3181 cggtgagaac ttggattctc gaccgctaca tcgcagactg catggagagt ggtctgcttt
     3241 ccgtttgcac cgacgctgaa gatgcgaact gaaccgcgca tggtggtcca gtccatatcg
     3301 agcgatgctc ggaacagctg agggccagtc tctcccacga tgagagcctt ttcgacagcc
     3361 atgttgttga ttgaaggtag gttcgtgtgc gtatcgaggc cgtggttctg gatgaggtgc
     3421 ttggcgaggg tgaaggcgat gtcggcgaag agagtctgca aatcgtcaag tcagtgatag
     3481 aatccagtac aaaagagaga gaggcctcac cgaaggagcc atagtcaatc cgttgacgcg
     3541 atggttttgc gcaatggcca agagagacgg gtcatgcatg tcagactcaa ccgtgataga
     3601 acttctctta tcaccatgaa cctgctcaat gacattatgc actgaatcac tcagcctcag
     3661 tgccctcgct tgtacaactg caccgaccgg gccattctca acgggagcgt cgcccttggt
     3721 aagacaccag ctgtacttgt actgcatcca gtagttggca agctgccaac tatacttggg
     3781 gagctgaaga acattgcgag aagatgcaaa gtcacgatgg tactcgtccc agttcacgga
     3841 gaagccagcc agatgcaaag cgcaaaggga atctgcgaga gtcttgaagt ggtcctcttt
     3901 gcggcggaga gacgcaaggc accggaagtc ttggccgatg attgacttga ccattcgcgt
     3961 gaggatggga tgggctccga tttcgataca catgccgctt cggtccatga tgccttgcga
     4021 ttcagccatt ttgatagcac cgaggaagtc aactgtctca cggcaatgac gtcggatgta
     4081 ctgaggacca agggtatcac cagtgagtag cgtgcgcaga agaggcgaga cgataggaag
     4141 tttgggttcg tggaacccaa cttgggacgc cagttcttcg aggtcatcta gaatgggatc
     4201 aacctgagaa gagtggaagg caaacggaat ctctagtttg tgaagcttgt agccagcctg
     4261 agtcaacttc ccacagagcg actcgatgtc cgcgttggga ccactaagga cagtgtcttc
     4321 agcgccgttg acacaagcaa tctcgacctt caagtcagat gagatgtgtt gcctcaaatc
     4381 atcagccgcc gctttgacag cgaccatgcc gtgcgtgtag gcagtgcact tcttgtcaag
     4441 aagcgctgcc ctgtgaccac agagaaagat ggcatcgttg acgctgagaa caccagcaat
     4501 ctgaagagca gcatactcac ccaggctatg tccgatgacg tactggggag tgataccgag
     4561 gctgatccag aagcgggcga gtgaaatctg gataatgcac gttccgagct gcacgacaac
     4621 tgcagagaga tcttcaacgg gtgttgtgcc gtgaatgagt gggagaacag atgggagtcc
     4681 ctgaagagtt gcgatggagt caagctggtg aatgtctgat cggaaggatg agaagctctt
     4741 gtagtaccca atggccatgg cagtctcctg cgctccctgt ccagtgaaga ggaagccgac
     4801 cttgggtgac actgcgggaa tgcccttgac ttgaccagca tcggtagcag ccttgagaag
     4861 agacttcctc aagtcgtcaa gaccgttggt gacaaacgca acacgtcgac tgtggtgtac
     4921 acgtcgagca gtagtcgtgt atgaaagctg agagagaagc tcaccctccg gagcccaaga
     4981 gttggcgatg taagcttcaa gggccttcag gttctcctcc aaagccttgg tagaccgcgc
     5041 cgagacagcc acgacatgct cagtacgagc atccccatct tgatgctgtc gtgctggatg
     5101 aacagcggga ccatcctcaa gcagcaatga agtgtttcca ccagcagcag agaagttgtt
     5161 caccaacacc ctgcgcttac cgccctcagg ccgagaccaa tccacgctat ccttcagagc
     5221 aatgcgcaca ccacgatgat ccaagtcctt aggaaaaccc tggttgatct tggtcttgat
     5281 accgcagtga ggcggaatcg tgttcttctg catcatcagc agcaccttga tgatggcgag
     5341 aactccagag gctgattcag cgtgtccgac gtttgctttg actgagccga gatacaagct
     5401 cttatcgcgt ggacggctgt gatcgaaggc gaatgagttg aggacggatc gcatctcaac
     5461 tgcatcgcca gcctgggtcc ccgttccgtg catctcgacg tagctaacat cgtgaggatg
     5521 gataccggtt tcgttcaaca gcttcttgaa gagatactcc tgggcgtctg cgagaggtcg
     5581 ggtgatggag acggactctg ctgagtggtt ggtgtgtgct cccaggatga ctccaaagat
     5641 gggatcactg tctgcgatag catctggaag gcgtttgaga atcaaggtgc cgattccatc
     5701 agcgcggcag taaccatccg caccgtcgtc aaaagccttg cagtttcccg tacgggaaag
     5761 gaaatgcccg cgatcgaggc ctgcaaagtt gtccgggttc gtcatgacat tggttccgcc
     5821 agcaatcgca gtgtcacaat ccctgttctt caacgacgtg atcgcaagat tgatcgcagc
     5881 aagactcgaa gagcaagcag tgtcaacagc gatactcggg cccgtgaact tgaaaaagta
     5941 attgaccctt ccaggaatga aggcacgatt ggctccagga atgtagtaag tatcaacatc
     6001 ctgtgaggag ttcacctcgc cccaatcgtt actcgtagta ccgtagtaaa ctcccacgcg
     6061 gttccgctgc gtggaaggag ttcggtccgg cacgacacca gccatctcga gggcttcgta
     6121 agccgtgagc agggcgagtc gctgagctgg atcagtctgc atggcttcct tgggcgacat
     6181 gtggaagaac tgggtgtcga agtaacctgc agactttaac cagcagccgt actggacttg
     6241 gctggtgttc ttgcgctggc cagtaggatc gtagtggtca cgagcaaagc gctcttcggg
     6301 gacaggttta tggacgtcga gaccacggat tagaagatcc cagaactcgt cgaggttgtc
     6361 ggcttctggg aatcgaccgc tgaaaccgat gatggcgatc ttgttctcat cgccaggagc
     6421 aagattgggt tctgctcggt ctttggtcag gctctccaag gttggcccaa tgcgagttgt
     6481 agctcctctc ttagccaacc aatcagcgag actgcaaaca gttgtttggg cattgaccgg
     6541 tatcaaggta gcttcagtgc cagaaacggt ttcgactaga gcgtcggtga cgagatccat
     6601 acgaatttgc tgagacagag cgctgctcaa aacgttcttg aggaggttcc cgaaagacaa
     6661 ctggtctaag cgagatccgg aggcgcagga gatgatggga atgagcatct cgttctctag
     6721 gaacccaacg tcttcaagga ttgatgcaag gccatgttcc aggctggatt cggagtatga
     6781 tgaagagtta tggtagggac catagatggg agctggatat aacctctttc cagagaaagt
     6841 atcgcaagac ttcactgact cgaggataga tgggggaccg ctgattgttg tgaaaccagg
     6901 accagtggcg ctgatgtagg gacgcgaact gtatgtaaga ttctgaaaca agaatgagca
     6961 ttactcaaat tgggaatacc aaagctctcg aacttacttt ttccttggag aattctttta
     7021 atgcttctga aacaagctcc tcctgattcg aagacagaat catggaccag ctcgaaggtg
     7081 tcgagtaccc aaggttctcg gctcttctgc gaacgtgcat tccaagtcgg aaggcaactg
     7141 tcgcagcttc aacgcccagt ctcgagatct cgaaaacatc cttcgcgcag ctgacagcag
     7201 cggctgcaat gctaccagtg cagataccga gtagcaaaga tggagctgcc ggcgggtgtt
     7261 gcttatccga acgagccaaa tagcttgaat ctcatcagca aaccgagaac ttgctcgttt
     7321 ccatcagact tactcaatgt agtatccaat ctcataaatg cacacaaaag cactatccag
     7381 cgccgcatga ggctcactcc tccgaacgcc ctccaaaagc aaactcaagc tctcagcctc
     7441 gggaatcgat tttctctcta aagacgagag cgaaacaatc tctcttcgca cagccaaaaa
     7501 cgcctcgcca agaaaggaag tcaaaagcgc attatctttc acgcgcacaa gggcttgcaa
     7561 tttatcaaga acgggtgtgc tctgatcgcc aaagacatac acatctgctg aggacgccat
     7621 cgtgaaagaa tggcaaaaat aatcgctgtt gaaagcagta atacaatgtg caatatttcg
     7681 tttgtcttgg ctgttttctt gccaagatgt atctggctta tactgtagag gtttagacct
     7741 gcatgcatcc tttttggtaa ttcgtaaagg gcctggcaga cgagctagtt agtgttgggt
     7801 ccgcgctttt gcgaaaatgt ccgtagtggc ttgcatgggt agtatagcgg ctaattacgc
     7861 cacgcaggat cagatcagag atgaagctcc gaagaggtcc gaattcttat ctggcagggg
     7921 aagctgaaac gggcagggtg gcgtagtagg tgccgtgaac cgaagacgaa tagagacaag
     7981 agaagagcca cgcagttgat gcactgatgc ctgtgccagc tggactctgt gccctgatgg
     8041 cgactcgaaa ctcggcactt gcatagactc ccattgattt tattgcctta gcaatccaaa
     8101 aatctgtggc cttgaggctt aattcctaga attgaacttg atgtgggctt atggaatgac
     8161 tgaggtgaat aaccatgtcg aaatctccga gggagcttaa tcgattgtgt agattataga
     8221 ctgtcaggag gttgatattt ctattagttg agcctcattc atatgatcta cataatgact
     8281 caaatgaatg aagagaatta gcgagcaaaa tatggcttag attgatatca aatgttctgt
     8341 agagaggcca ttctaagagc caacctcaac gaccccagtc gctgcctgca ctggattccg
     8401 aagtcccaca aactcattcc gctgctcaga ctccttgata ctcgcagcct gtttactctc
     8461 cttctcctcc gcctccttaa cctccttggc caccctctgc cgtctcgcca tctccgcccg
     8521 cgcctcctca acagccttgt tataaagatg ccctcgagcc gtaagctcaa catcctccag
     8581 atacggcgca gcagaaagtg ccataaaggc acgcaaaagc cagtcctcgt tactaagctt
     8641 caacatgtct ttgacaagag tagttgcagg tccaggagtg caaagcagtg cttttccaac
     8701 catttgggat ctctccaggg ctgttgtagc tggctgtgcg cgctcctgag catagcttgc
     8761 gagtacggac ttgacgacgt cgctagacag cttgtcgcct gactggcttg cctttcgcgc
     8821 tgccatgagc ttgttgacga agacggcgca ggactctatg gcctggttgg cgccttgtcc
     8881 accagccggt gtagtcttac aagctgcatc gccaacaatc acagcgcgat cggtgtgcca
     8941 gcccttcgcg acaccttctt caacgccaat cttgaccgcc actacactgt tcttgtagat
     9001 ctcaccaaac ttgagcttgg gagtgacctg tgtatgagcg acgcttagac agagagcctc
     9061 tgcttcagct tcagtgtatc gcggggcctg agagagcggg acgttccggt tcagattctc
     9121 aaatacaaac cagaatacga ttccatcttt gcccgtgaag ccgataactg tttggttctc
     9181 tcggtagacg gcgaagcgtt caccgggggc gataccttcg gtgggtgctg acatgccgta
     9241 gactgtggag caggcaacgc tgatgtctgg ccatacgtta gtggaaactc accatgatca
     9301 gctttgtgca taactcacaa tcatctgcag tcaatggttc aggcagcttt gagtcaatgt
     9361 gtgtgcgtac agcgcttcgc acgccatcag caccaacgac aatgtctgca gtaagagaca
     9421 agccgtctgt tgttgtaaca gtgacatggt cctcgctctc ctcaattgaa gcaacgcgtg
     9481 ctgaagtctt aacacattct gtgcgctgaa tgtgtcgtac catgataggt agcagcttgc
     9541 ggcgctcaat gaaggcaaca ggatatccga tcctagcacg taccccatta gccgacactc
     9601 gaaataaaca aaattcaatt atactaactt gtcacgatat tgacccatgg cgtcagagtc
     9661 attcatcaag ttcccctcgc tgtcataaga gaaccacttc tcaagcggaa tagtagcctc
     9721 ctcaatatcc tccacgagac caagctgatc aagaatacgg aggccatttg gctgcagacc
     9781 aataccagcg cctctatcag actcaagagt atcgcgaccc tcgaggagga aatagctgat
     9841 gtcgagtttc tcaaacatca gcgcgagagt aactccagcg attcctcctc cagcgatgat
     9901 gacttcataa tgctggtttg gttcagccat ggtgatagtg agatggagta gaatattctt
     9961 tgaattacga ttgcctcggt ttacgggctt tcagaaggga tagagtatcc tttagggcga
    10021 tgttgtttat ttgagcaggc agcgcctcac tagtgtagct tatgcataag caccggccga
    10081 agatatccga attttaaaag tcgcctcatc cacgcatggt gaaacacgca gaaatcggag
    10141 gacttcggac ttcctaaaca ggtaggacac tgcagttcct ctattgtcca atattgcagt
    10201 tgtacacaaa tggcaccact ttatagacct gataagcctc taggaatttc catcttctca
    10261 gcatcatctc atcaaacagc aattcaacat tatcttcctc gtcttgacat tcacaaatca
    10321 catcgcccaa catggtttca aacggcattt ctaacggtac caatggtaca aacggcacta
    10381 ctaccaatgg caccaatggt gtcaacggac atgccgccct gtcacccctg gaggtcttag
    10441 tccaagatct caacaagaac accaccacat tgaacgggta cctccgcgcc aacaaacttc
    10501 ccgagcctag cttcgagcgg gatgcgccca ttatcaactt atcgcctgat gcacctgaag
    10561 aggcgcaggt tgctaaggag aaggtgctcg acagtgcgct gcaaatcttc cagcttgtct
    10621 ctggcccagg cgagtacttg caaaacgtca tcacaggtgt aggtacccca ccacaaacat
    10681 ttgctatagc tttgaatgac cattatagta tcattatatg gagatcctcc gatggatgag
    10741 ccacttcaag atcttcgagc ttgttccctt ggagggcaag atctcataca cagagctggc
    10801 ctccaaagct ggcgtagctg agttacggct caagactctt gcccgtatgg gcatgacgaa
    10861 ccatctcttt gccgagcctg agcctggctt catcgctcac tcagctacct cagccgctct
    10921 ggtgaccaac aacagattct ctgaccagag agtctggatg acaagcatca ttgccccagt
    10981 cattgcatct atggtcactg cgcatgagag gtggcctgat agcactgctc ctaacaaggc
    11041 agctttcaat gctgcgttca acactgatct ccgcatgtat gagtacattt ctaagcagcc
    11101 tgatgtttac aagctctttg gtcgtgtcat ggatgcgatt gccactagcc ccaagagtga
    11161 cttgaagcac cttgttagtg gctttgactg ggctggactt ggcaaggcca acgttgtcga
    11221 tgtaagtatc tcccgcgcct atcacactgc agaagctaac gtatctcgtg aagattggag
    11281 gcaacatcgg ccacagctgc gtgaagctag ccgaggcctt ccccgatctc aacttcatca
    11341 tccaagacat cccccacgtc gttgaagaag gcgccaaagt catcaaggag aacaacgagg
    11401 ccagcatcgc caaccgtatc caattccaag aatacgactt cttccagaag caaccagtcg
    11461 tcggcgctga tatctatctc ttgcgccaga tctttcacaa ctgggatttt gagaactctg
    11521 tcaagatcct caagaacact gttgagtcta tgggtcagaa ctctcacgtg ttgatcatgg
    11581 actttgtggt gcctgagcct ggcaccgtct cgtctgtgaa cgagcgtgtt cttcgatctc
    11641 gtgatgtggg catgatgcag ctgtttaatt ctcttgagcg agaccttgag ggctggaaag
    11701 cgattttgga ggcggtggac tcgaggctta agattaatgc tgtcaacacg ccatatggca
    11761 gcttcatgtc ggtaattgat gtcgttctag ggtaggggat taatagattt agttacgcga
    11821 ctttagccat tccatcaaga ttagaaacac gataaatttg atgcagcttg cttattccta
    11881 ttattgcttg tatttttaat ctaattgagt gatggctctt gtctccacga aattgttgcg
    11941 agcagtggca tggaataata aactaattcg tctcacgttc gaggttcaag ggtcgtatgc
    12001 agctgcgctc agccaaaaaa gaccgtgctt caatgatagt cgatatcatg tgcattagta
    12061 tctgtacact tgtacactaa agatcttgag tttactatca tctgaaccta attgactgac
    12121 agttcgtccc ataatcgtga actgacgctc ggtgacaact gacaaccagg gattgccatg
    12181 ttcagatact cagatcgcca agatgaagtg ttgccagatt tggtcatgac acattccagg
    12241 ggttgccaga gcgagccaat cgcgggtcgt ggttatgcga ttatgcgaga tggcgagact
    12301 ccacacccgc gtcctcgggc tgcttatccg agacttgagc gacgcgacga tcgctgagga
    12361 tgacgctgaa gttcggaaat ctcagcaatt acaggcggac atcttcggac cttgaatgtg
    12421 agtacataaa cgctgatacg tcaacacact ctgcctcacc gaaacaagct tcagctgccc
    12481 taccattcca ccctactgcc ctgtactgta cctgtaccac cttgaactga caccctgaac
    12541 catccctgct tatctcgctc actaccatgc catctccaca tttctccaaa gtcctcgtct
    12601 ttggtgcaac cggcgaagtt ggctccgccg tcgcactcga ggcccacgct ctcggcgccc
    12661 acgtctccat cgccctacgc gacacaacca agcacaacga gtggatctct ccctcacagg
    12721 aacacgccgc agacctgcag cgcatcagtg ccgacctaac cgatcccgac tccctgaagc
    12781 gggccgtgca tgacacaggc gcccaggcag ctttcatcta cgccgttcga tccaaggaca
    12841 cgttgcgtgg tgccatcacg gccctgcgcg acgctggcat ccagtacctc gtcttcctgt
    12901 cgacgagtca ggttaggacc gcgggcacca ccaagggtga cattcgatcc atcaagcctg
    12961 accacttcat cccatggcag catgcgcagg ttgagattgc gctggaggag cttgaggtgc
    13021 cacatgcagc ggtccgggcc gggttctttg cgagcaaccc gctaagaatt taccttgatc
    13081 gatcttcgga gcctaaacaa gtcaatttgc tagctccgga agtgccgcat gatcccattg
    13141 accccaagga tattgggcgt gcggctgctg ccgtcttagt caacccgcgg ctgtatgcga
    13201 gtggctatca gggagagcca aagaaggacg tcgtttatct aagcggaccg gccttgctct
    13261 cgcagactga gcagtgggag attatcaacc gggagcttgt cgctgcaggt aagcctgagg
    13321 tcaaggtcaa tcacattacg gttgagcaat accttgagaa tctggccaag ctccatgttc
    13381 ctgatgttgt agccaagtct cttgctaagt ccatggttga gacgagggca ctgtatgctc
    13441 ctgaggatta cgagaagtcg cggggtaatg ttgagctttt gacaggccgc aaggctacag
    13501 catttgatga atttgtcaag agagagatac caagatactt tgactaaatt tagactggac
    13561 gcgctatgct tcaagataga gatgccatct acatttcata tagaatagcc tttgcattca
    13621 actaaataga cacctcttat taaacatttc tatcttgctt gcagtagcct ttctatggat
    13681 tgttatttgt gcagggaacc cgagagtcta acagtggtca atgccaggtg atctgatcaa
    13741 ttgaatctcg gtagcccaag atcaaacccc gccagagatg atgccccatg ctcagcatct
    13801 acccacggcc actccggaat catatccatg aaaggaccca aagtctccgt cccaagtact
    13861 ctctgtagag catctgactg accactgcta tcaagtggca ctgttgccat accaggcaac
    13921 gatgcttctg accctggtat agaaggcggc gtctgctgca acggcccgta ccagttatta
    13981 gagtacgctg gtgttggata ctgcgagaaa agccctggtg aaggagagta caagacagga
    14041 tctcttctct gaactttacg gccagcattt gacgaccgcc caggagtcgt ctgttgcatc
    14101 tctttgacat agcgagcttt agccatgagc ctctttatag gtctccataa agcaaggcga
    14161 gtctcatctt gtttgctctc atcgaccttc catccctcgt atactgtcgt tacgcagtcc
    14221 catgcctgat cacattgtgc tgattgaggt cgagcgcaca gctcagagag gacaaatgcc
    14281 atggcgcccc attggatatg agtcttggag taccatgtga attgtatgat ctccttgctt
    14341 gtgagaagca tgccagatac ctccagtatt ttgattgaag tttggaagag ctcgtcgcgc
    14401 actttgttgt ccagctggcc tgcggtgttg ggagtaggag ggaattggtt gctcgtgctc
    14461 ttaccatcaa cttccctttc tcgtgacact actgagtact gggttataag ccagaatcga
    14521 ccaaggatga tttgtgcaac tgccgaggaa agaagctgaa atggtactga agtatcacaa
    14581 atgggtagat acttgtcccg caaccgactt tctaattctt ggatcagagt tttgggagta
    14641 tctgaggtgt catctaccct tggggtactt ccatcctctg atgttttgtt ctgcttgtgc
    14701 ctcatgcgac ccagcttcag acctgtctgt atagcctcac acctgaccaa cgtgagcgtc
    14761 atatcagtcg catggtccca tcgttcagct ggaggctcca ccatctcggg tgacaaatca
    14821 acatcattga tgtgcagtgg aggtttggta tctgtaataa acccttgcgc aataggttca
    14881 ttgcagtgat actctgatga gcggctatcg ataatgcaga tctgccacca taaacggcgg
    14941 cgcagctcag tctcgaaggg ctttagtccg aatatggtgc catcgcgatg gagacccatg
    15001 gttctggcaa tatggaagac cagcgatgtg agtgcccatg cagcacgcga gtcatcttca
    15061 ttcggcagag cagacaagaa aagcactgcg gcttgcaaca tggtcatact ctgagtgctg
    15121 aggaggttgc cttgagcgag ggcttgttca actgcaaacc gatatctttc cagggcagct
    15181 tcacgagttt catcaagaat attcagacat tgctctgggt tgagactgat gaccgctgag
    15241 taatggatag tgaacaacag ggtctcggta tgcttatcca ctgtgccaag agatgcgatg
    15301 gcatcccagt agattcttgt caaggtcggc atgtgaaata tgcggaccag cggcgcgaca
    15361 ttctcactga atgcggcaaa aagcgtgact gcctgttgca gtgagggatg gtaatgatag
    15421 agaggtgaag caatggcgcg atagccaaaa atggcggcgt tgagtcctag ttggggagat
    15481 gatggtgaag tagctgcagt ggtggcagat gaagagatgg aaggctcgta gccagcatct
    15541 tcactagcag gctcaaagag gagatcacgc agctcctcaa cctacagata gtgtcagtca
    15601 cgaagaaata aaagcaaaga agtaatgaag gacatgcctc gtttgataga gtaacccata
    15661 atgcattatt cacatagtag ctctttgact catcgacctt gagacgacta aagtcctgct
    15721 cgaatgaatg accctcactg tcttgggcag tctgcggggt atcctggttc tctctggcta
    15781 tgtaattgtt agatggaatc tgcagtgagt gagtgtaagg ctgcatttca cttaccagcc
    15841 gcaccgaact gtccaatgat gctctcaagg cgcgacaaac gctctgatag ttggggcgca
    15901 aggctgcgtt tcggcctctt gggtgctctc cctcgaccag gcgggtagat gcaattgact
    15961 tcagatctga tacaattaga acattggggg aattggcggt cgcatttgac tctgcgttgg
    16021 cgacagtgga tgcaggtccg cacttggacg tgcgactgag ccaggcctgg catggagaga
    16081 ttgcctaaag cagagtccat cttgctgtga ctgacaagag acgtcaagaa atgattaccc
    16141 tagaggatgt gtgctcgtgt cttggcaatg ttaattgcag gttggataga cgtatggcca
    16201 tgtcgttgga atgtctcaga ggactcaagg tcgggcgagc gaagcagcgg acaattgtgc
    16261 gagagagtgc cccgcagatg atgatcagcg ccgctattgg cccggcagtc gcataactta
    16321 tgcgaggtgc gcgagcgagc gagacagcga aaacactcgc gaaattggcc attacgggca
    16381 tcaggagaaa acacatgatg ctagcgctga gagaaaacat gataaaggcc tgtaaagaaa
    16441 tccgcaaaag gattctctcc cacggaaaag cacctcaacc actgatacaa ggagtacttt
    16501 tgcccttatc ttgccgccct ccagtacatt ctagacttgc ataccccgcc aaatcacgga
    16561 gagacaggct ccactgaatg atctgacagc tagcagcagc agcagcaaga tgaacgaaga
    16621 gtccaacatg ggtggtgtct tcaaggaaga ggaagcgcaa tcgggcgacg tggtcgactt
    16681 tgagggagac tccgacaccc acaacccgca gaactggccc atggggaaaa aggtgtatac
    16741 gacagccctg tgggccctga ctacctgctg gatcaccttc gcctccgcca tctactccgc
    16801 cggcacagca gagattagtg aggagttcca tgtgtcgtac gaggtagcca acgcgggcac
    16861 cagtctgctc atcttcgggt ttgccctcgg acccatgctc tgggcgcctc tgtgtgaggt
    16921 ttacggtcgt aaatggcctg ctctcgctgt aagaccccat tactgctgtt acagtgaagt
    16981 tacagcaccc gctaactaac ctcccctagc cctatttcat tagcgcagcc ttcgccttcg
    17041 gcactgcgac cgccaaggat atccagacta tcctaattac aaggttcttc gccggcgtct
    17101 tcggcagctc ccccatctcc atcacaggcg gttccatcgt cgacatctgg accccacgcc
    17161 agcggggcac ccccatggtc tgctacggca tcaccatcgc tgcggccccg accctgggac
    17221 ctatcatcgg cggcgccttt atcgccagcg gctgcggctg gcgctggacc gagtacctga
    17281 ccggcatcgt catgatggtc cagttcgtcc tagacgcctt gtggctggat gagagccacg
    17341 ctgacgtgct tctcactcgc aaggcaagcc gcctccgtcg gtctacgggg aatttcagtc
    17401 tccacgctaa ggtacgtgag atcccatgcc gggtccataa tcttcccgct tatggtggcc
    17461 cttcccttcc gtggctgata tcttggctga aacaaaacaa aaatattaca gtgggaggag
    17521 actagcccta cgttcaagag tctactgagt acctaccttg tccgcccgtt tcagatgctt
    17581 ctggatccca tctgcttact gctcacgatc tatacctctt tcgtctatgg taagcgctac
    17641 aaatatcccc agcccaaatt caacgttacc tgtgctgtgc cagcatcatt accttcccaa
    17701 accctgctga ctcatgggga ctttttccag ccatccttta cgcgagcttg gagagtttcg
    17761 ctctcgaata cggccggttc cgaagatggg gccccgtcgt gagccagctt cccttcctgt
    17821 cgctcttgat tggctgtctc tttgccgccg cggccaacat cttcaacaac atctattacg
    17881 gaaagaagct cgtcgccaac aacttcaagc ctgttcctga agcgagactt ccaccaatga
    17941 tggtgggcgg cttcgccttc tctgcaggtc ttttcctttt tggctgtaag tcgcaatatt
    18001 tcattctcgc tagcggaacc gccccgaacc tacatgacaa ttgtggagat gacttgcata
    18061 gacgactgac ccgttattct catcgtttca gggacctcgg ttgagcacgt ctctagccca
    18121 tggccatcca tcattggcgt cttccttact ggggttggct tcaccaccat cttccaatcg
    18181 tccctccagt atctcgtcga tactttcacc cgctacagtg ctagcgctat tgcggctaat
    18241 acttttgtcc gatccatggc tgcaggtgct ttccctctct ttgtctggcc catgtatgaa
    18301 aagatcggca tcgattgggg gagcactatc tttgcctgca ttagcgtgct tctgctgcca
    18361 gctccattcc tctttttcaa atggggttat cggatcaggg cccgtggcga attcagcaag
    18421 ctatcaacct attaa
//
