BGC0000030 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000030 (Fusarium fujikuroi IMI 58289)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	46,271	High	bikaverin	PKS

BGC0000030 - Region 1 - T1PKS

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Location: 1 - 46,271 nt. (total: 46,271 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 46,272
Label		BGC0000030

Tailoring functions

Transferases: acylase methyltransferase

FFUJ_06742: malonyl CoA-acyl carrier protein transacylase

smcogs: SMCOG1021: malonyl CoA-acyl carrier protein transacylase

FFUJ_06744: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

Hydrolases: hydrolase

FFUJ_14916: alpha/beta hydrolase domain-containing protein

smcogs: SMCOG1066: alpha/beta hydrolase domain-containing protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000030.3	1.00	PKS	bikaverin	Fusarium fujikuroi IMI 58289
BGC0002175.3	0.68	PKS	YWA1	Aspergillus oryzae RIB40
BGC0000107.3	0.68	PKS	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001258.3	0.68	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001257.3	0.67	PKS	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002154.2	0.67	PKS	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001284.4	0.67	PKS	alternariol	Parastagonospora nodorum SN15
BGC0000037.4	0.63	PKS	cichorine	Aspergillus nidulans FGSC A4
BGC0001276.3	0.63	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001273.3	0.63	PKS	asperlactone	Aspergillus ochraceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000030.3	1.00	PKS	bikaverin	Fusarium fujikuroi IMI 58289
BGC0002175.3	0.68	PKS	YWA1	Aspergillus oryzae RIB40
BGC0000107.3	0.68	PKS	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001258.3	0.68	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001257.3	0.67	PKS	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002154.2	0.67	PKS	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001284.4	0.67	PKS	alternariol	Parastagonospora nodorum SN15
BGC0000037.4	0.63	PKS	cichorine	Aspergillus nidulans FGSC A4
BGC0001276.3	0.63	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001273.3	0.63	PKS	asperlactone	Aspergillus ochraceus

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 46271:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

FFUJ_06742: mal

PKS_AT (908..1206): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 62.5%; Methoxymalonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 94.0
Methoxymalonyl-CoA: 59.5
Methylmalonyl-CoA: 56.4
inactive: 38.6
Propionyl-CoA: 28.3
Ethylmalonyl-CoA: 20.4
Isobutyryl-CoA: 17.5
fatty_acid: 17.4
Benzoyl-CoA: 16.9
3-Methylbutyryl-CoA: 16.1
2-Methylbutyryl-CoA: 16.1
Acetyl-CoA: 15.4
CHC-CoA: 15.2
trans-1,2-CPDA: 11.8

Link to PARAS substrate predictor