BGC0000034: candicidin biosynthetic gene cluster from Streptomyces sp. FR-008
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Location: 1 - 138,203 nt. (total: 138,203 nt).
This entry is originally from NCBI GenBank AY310323.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000034
Short description candicidin biosynthetic gene cluster from Streptomyces sp. FR-008
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: AY310323.2
Compounds
  • candicidin
Species Streptomyces sp. FR-008 [taxonomy]
References
Chemical products information
candicidin
Copy SMILES
C59H84N2O18
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAQ82549.1
  • fscO
 574 - 1950 (-) FscO
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  • AAQ82550.2
  • pabC
 2264 - 3037 (-) PabC
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  • AAQ82551.1
  • fscRI
 3150 - 3818 (-) FscRI
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  • AAQ82552.1
  • fscRII
 4377 - 7205 (-) FscRII
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  • AAQ82553.1
  • fscRIII
 7210 - 10254 (-) FscRIII
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  • AAQ82554.1
  • fscRIV
 10298 - 13315 (-) FscRIV
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  • AAQ82555.1
  • fscMI
 13522 - 14898 (+) FscMI
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  • AAQ82556.1
  • fscMII
 14953 - 16011 (+) FscMII
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  • AAQ82557.1
  • fscP
 16106 - 17287 (+) FscP
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  • AAQ82558.1
  • fscFE
 17334 - 17528 (+) FscFE
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  • AAQ82559.1
  • fscTE
 17556 - 18413 (+) FscTE
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  • AAQ82560.1
  • pabAB
 18610 - 20781 (+) PabAB
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  • AAQ82561.1
  • fscA
 20927 - 26158 (+) FscA
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  • AAQ82562.1
  • fscTI
 26333 - 27340 (+) FscTI
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  • AAQ82563.1
  • fscTII
 27561 - 28280 (+) FscTII
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  • AAQ82564.1
  • fscC
 28983 - 60860 (-) FscC
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  • AAQ82565.1
  • fscB
 60962 - 77587 (-) FscB
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  • AAQ82566.1
  • fscF
 77983 - 84132 (-) FscF
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  • AAQ82567.1
  • fscE
 84170 - 107485 (-) FscE
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  • AAQ82568.1
  • fscD
 107496 - 136148 (-) FscD
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  • AAQ82569.1
  • fscMIII
 136558 - 137766 (-) FscMIII
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
fscA
Module ?
Specificity: para-aminobenzoic acid
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
  • Fixed biosynthetic classes
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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