LOCUS       BGC0000045             31000 bp    DNA     linear   PLN 08-MAR-2013
DEFINITION  Aspergillus terreus strain AH-02-30-F7 dehydrocurvularin
            biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0000045
VERSION     BGC0000045
KEYWORDS    .
SOURCE      Aspergillus terreus
  ORGANISM  Aspergillus terreus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 15:06:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 31000
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..31000
                     /db_xref="taxon:33178"
                     /mol_type="genomic DNA"
                     /organism="Aspergillus terreus"
                     /strain="AH-02-30-F7"
     subregion       1..31000
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..31000
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(join(<641..1458,1515..2153,2212..2670,
                     2811..>2916))
                     /product="putative phosphorylase"
     CDS             complement(join(641..1458,1515..2153,2212..2670,
                     2811..2916))
                     /codon_start=1
                     /note="orf1"
                     /product="putative phosphorylase"
                     /protein_id="AGC95328.1"
                     /transl_table=1
                     /translation="MLAPQVKGLSAEVERLAHSVTFKTYPSQVEQQGGPTFLQIFGKHH
                     VGSGGWDWTASRVLSVLTSYRPSDRTYSDFWIGLLCAKSLEATALTAVLDEQYDRIGRV
                     PGDSNAYTPGRIGEHNVVIAQLPAGTPGTAAATAVAKDMLRTFPHIRVGLFVGIGGGVP
                     GPPSHNPEKEVRLGDVVVSEPGDGHGGVIQYDFGKTYHDGAFVTTGYLQRPPDVLLTAL
                     SQLRSRHDLQGNSIAKCIQTMRHRYPRMASRWEYPGAECDVLYASDFPHPGRGRTCAEL
                     GCPTRAERVVKRAKRGTSDPAVHYGLIASANNVMRDSKTRDALREKYGMLCFEMEAAGL
                     MSNFPCLIIRGISDYSDSHKADDWQDYAAATASAFTKELLEVMPAFDMQQTPTAANSME
                     SVIYRSAAELRRDIQPLLAGNELQESQAVLDWLAPAFHEGQHDDIRMKRTRGTCRWFLT
                     HPTFLNWMERGKSPQILLCQGLPGAGKTTLASTVTDYLRENNSVSGPIVACIYFNYKLS
                     GQQTSDVILRSILRQVTHLSSIPEPIKSLYALCRAGSRSPTLAEIEDTMERMLSSQDRP
                     VFLIVDALDECSPPHLSDFLGVLWCLQKTGVQILLTSRHVDRITTEFRQARDFSKMEIR
                     AERTDVAAFIQQHLATITHGGINIDRIIGIIHSAANGM"
     misc_feature    641..30911
                     /note="dehydrocurvularin biosynthetic gene cluster"
     mRNA            complement(join(<4218..8105,8168..8371,8428..10005,
                     10069..10354,10407..>10702))
                     /gene="curS2"
                     /product="CurS2"
     gene            complement(<4218..>10702)
                     /gene="curS2"
                     /note="atcurS2"
     CDS             complement(join(4218..8105,8168..8371,8428..10005,
                     10069..10354,10407..10702))
                     /NRPS_PKS="Domain: SAT (8-246). E-value: 9.1e-55. Score:
                     177.6. Matches aSDomain: nrpspksdomains_curS2_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (368-799). E-value:
                     1.9e-135. Score: 443.9. Matches aSDomain:
                     nrpspksdomains_curS2_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (896-1189). E-value: 5.2e-87.
                     Score: 283.8. Matches aSDomain:
                     nrpspksdomains_curS2_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1272-1589). E-value: 3.1e-90. Score:
                     294.5. Matches aSDomain: nrpspksdomains_curS2_PT.1"
                     /NRPS_PKS="Domain: ACP (1645-1709). E-value: 7.5e-15.
                     Score: 46.9. Matches aSDomain: nrpspksdomains_curS2_ACP.1"
                     /NRPS_PKS="Domain: Thioesterase (1809-2058). E-value:
                     1e-18. Score: 60.4. Matches aSDomain:
                     nrpspksdomains_curS2_Thioesterase.1"
                     /codon_start=1
                     /gene="curS2"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 72.5; E-value:
                     4.5e-22)"
                     /gene_kind="biosynthetic"
                     /note="nonreducing polyketide synthase for
                     dehydrocurvularin biosynthesis; AtCURS2"
                     /product="CurS2"
                     /protein_id="AGC95321.1"
                     /sec_met_domain="PP-binding (E-value: 7e-15, bitscore:
                     44.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7.6e-88, bitscore: 283.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 2.9e-137, bitscore:
                     446.9, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDSNRPAVLLFGDVTDPWVDGIDYVYSQAATTPWLRSFLRDLFTV
                     LKVEMRTMDRTLQESFRDCGSFQELAERYRHTGDDFGMAHAMLTYVIRAVVLLETISAE
                     PHLLDSNRPRPELIGVSGGLFSAAVVSVSTNFQSLYDTCLEAGRVWARLCNLTLVKSRA
                     IEERPGTWGWAVLGIPAGKLSQTLEQFQNDMGVPSAKRARVGVTGDRWSTVIGPPSILE
                     LVLNECPTLKNLPKNELDIHALQHTLDISNADIDYIVGDSSLLDTPLPQGYRIYGLDDD
                     RPEATYPSWSHLLRASASQTLARPLNIVQAVSKLNAALGTSTHVDFKIMGPSSHAAYIA
                     KVLQTAGREVSLQDRITAKPPTPDSRDGIAIVGMAGKGPGSDDLEEFWDVLLKGLDLHQ
                     EVPPDRYDLDEYYSPKHPPAGPGKCTMTCRHGCFMNNPGHFDSKFFHISPREALLMDPA
                     HRLFLMNAYEALEMAGYSDGQTKMTDPTKIATFFGQCNDDWHVVGHRTLGCDAYTLQAV
                     QRAFGPGRLAFQFNWEGPTYALDSACAATSSCIHLACMSLIARDIDMAVAGAANVLSTP
                     HSFTSLSRSGVLSDSGNCKTYRDDADGYCRADFSGAVVLKRLDDAIAHNDNILAVISSS
                     ARNHSGNSTSITTSDAAAQERLFHKVLRNARVTPEDISYVEMHGTGTQVGDKAEMGAVS
                     SVFSKRRDGELLPVGAIKANLGHSEAAAGMSSLLKSILMFQKGTIPPQAGMPHTLNPNF
                     PPLHEINIKIPEEPLEFKSVGGKPRRILLNNFDAAGGNACLLLEDYTHTKEREADVRSA
                     HTIVTSARTQASHLLNKQRLLKWLRSNPNTRIEDLAYTTTARRMHHPIRFALTASTTQE
                     AISKLESEIERNTNSPASRHVPVVFVFTGQGSHYAGMGAELYRTSSAFRERVDLCVDIC
                     AGNNFAPFVDIITDEGVDVSSKTAAQVQLAVLTLEMALTHFWRLAGIEPAMVMGHSLGE
                     YAALHAAGVLSLADALYLVGHRALILQERCESGSCSMLSVSTSVANVREQLSQLQSSSC
                     GVACINSPSSTVVSGIAEDLAEFQANITAQDAKVRTKTLSIPFAFHSFQMDPILQDYGT
                     IAAGVTFSAPKIPVASTLLGSIVGEPGVFDHDYLVQQTRQPVNFVGGLNAVQSKLSDPL
                     WLEIGPSPVCVSFVRDTLSPSLSKLTHTLQPNTHNWASISKSLAAAYINGVDIDWVALH
                     APYETNLQLLTLPSYAWDVKDYWITHTDRVTEAVPEQSPVTGSGPLVSTCAQYLVSKSS
                     SPKVQVVFRASISDPGFMELIDGHKMQGIGLCSGSVFCEAAFAAAKYALEYSGRRNVTQ
                     PWLTLQKPELLLPLTKKLAGADGSLITTAVMDSPSAHRISVTFKLTSGSESHELGSCIV
                     NFRDPAKTQADWDRVSYFIQARMDEVIKNAKEGPGHRMQPEVFYALFANAVEFSTDFQG
                     VDEAYIAKDFQEAAALVTLPHDPAGTKFTFSPYWGEALVHLAGFMVNGNPSKSPQKTFI
                     VMGFESVEQTVPLVPGKKYMAYTRISKWVKETAYCDAVVFDPETSNIILQCIDLRYQEL
                     PRVTWKHVLDGPHGGSSAHGHKAPVQETKKAVEVSRQAVAVAPVQPQPAEVGEDDDDDF
                     DEGLVDAILDSISKATGSDPSEFTDDTIVADLGVDSIMAIEVVATVKEQSGLDLPATFV
                     LEHPTIGDLRRAFGANKPKTSKPQPGSTTPSSSQSSIPSSPNPEPTSMSDTASSLGSSL
                     VDIEKDQTFTPPPELEPKPNHHLGKMDETDTSPAPTVRITLLQGRPSPKRTPFYMMADG
                     TGTIATYIHLPAFKSKMPVYGIDSPFLRCPSRLTKDVGIPGVAKLIVDALVTAQPTGPL
                     MIGGFSAGSIVAYEVTRQLGALGRQVTGLVLIDMCCPRSSLLDEDAMNSEDDASFAIFE
                     NAVSKDGLWSLASTTQDHFRAYHVAMHAYHPPYMTAQERPSHTAVIWAEKGMVNRVVGN
                     DRLMQMLADQGIPTTSYPGYMEDPRLGAFACLVPDRTAADLGPNGWEKYTAGEVLALSV
                     AGDHLDLPMPGHVHLLQREMEKAFAYFEGEST"
     aSDomain        complement(4296..5042)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS2_Thioesterase.1"
                     /evalue="1.00E-18"
                     /label="curS2_Thioesterase.1"
                     /locus_tag="curS2"
                     /protein_end="2058"
                     /protein_start="1809"
                     /score="60.4"
                     /tool="antismash"
                     /translation="YMMADGTGTIATYIHLPAFKSKMPVYGIDSPFLRCPSRLTKDVGI
                     PGVAKLIVDALVTAQPTGPLMIGGFSAGSIVAYEVTRQLGALGRQVTGLVLIDMCCPRS
                     SLLDEDAMNSEDDASFAIFENAVSKDGLWSLASTTQDHFRAYHVAMHAYHPPYMTAQER
                     PSHTAVIWAEKGMVNRVVGNDRLMQMLADQGIPTTSYPGYMEDPRLGAFACLVPDRTAA
                     DLGPNGWEKYTAGEVLALSVAGDHLDL"
     aSModule        4296..9483
                     /complete
                     /domains="nrpspksdomains_curS2_PKS_KS.1"
                     /domains="nrpspksdomains_curS2_PKS_AT.1"
                     /domains="nrpspksdomains_curS2_PT.1"
                     /domains="nrpspksdomains_curS2_ACP.1"
                     /domains="nrpspksdomains_curS2_Thioesterase.1"
                     /final_module
                     /iterative
                     /locus_tags="curS2"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(4791..4865)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS2_0004"
                     /evalue="8.60E-09"
                     /label="NRPS-te1"
                     /locus_tag="curS2"
                     /protein_end="1893"
                     /protein_start="1868"
                     /score="27.8"
                     /tool="antismash"
                     /translation="QPTGPLMIGGFSAGSIVAYEVTRQL"
     aSDomain        complement(5343..5534)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS2_ACP.1"
                     /evalue="7.50E-15"
                     /label="curS2_ACP.1"
                     /locus_tag="curS2"
                     /protein_end="1709"
                     /protein_start="1645"
                     /score="46.9"
                     /tool="antismash"
                     /translation="ILDSISKATGSDPSEFTDDTIVADLGVDSIMAIEVVATVKEQSGL
                     DLPATFVLEHPTIGDLRRA"
     aSDomain        complement(5703..6653)
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS2_PT.1"
                     /evalue="3.10E-90"
                     /label="curS2_PT.1"
                     /locus_tag="curS2"
                     /protein_end="1589"
                     /protein_start="1272"
                     /score="294.5"
                     /tool="antismash"
                     /translation="STCAQYLVSKSSSPKVQVVFRASISDPGFMELIDGHKMQGIGLCS
                     GSVFCEAAFAAAKYALEYSGRRNVTQPWLTLQKPELLLPLTKKLAGADGSLITTAVMDS
                     PSAHRISVTFKLTSGSESHELGSCIVNFRDPAKTQADWDRVSYFIQARMDEVIKNAKEG
                     PGHRMQPEVFYALFANAVEFSTDFQGVDEAYIAKDFQEAAALVTLPHDPAGTKFTFSPY
                     WGEALVHLAGFMVNGNPSKSPQKTFIVMGFESVEQTVPLVPGKKYMAYTRISKWVKETA
                     YCDAVVFDPETSNIILQCIDLRYQELPRVTWKHVLD"
     aSDomain        complement(6903..7781)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS2_PKS_AT.1"
                     /evalue="5.20E-87"
                     /label="curS2_PKS_AT.1"
                     /locus_tag="curS2"
                     /protein_end="1189"
                     /protein_start="896"
                     /score="283.8"
                     /tool="antismash"
                     /translation="VFTGQGSHYAGMGAELYRTSSAFRERVDLCVDICAGNNFAPFVDI
                     ITDEGVDVSSKTAAQVQLAVLTLEMALTHFWRLAGIEPAMVMGHSLGEYAALHAAGVLS
                     LADALYLVGHRALILQERCESGSCSMLSVSTSVANVREQLSQLQSSSCGVACINSPSST
                     VVSGIAEDLAEFQANITAQDAKVRTKTLSIPFAFHSFQMDPILQDYGTIAAGVTFSAPK
                     IPVASTLLGSIVGEPGVFDHDYLVQQTRQPVNFVGGLNAVQSKLSDPLWLEIGPSPVCV
                     SFVRDTLSPSLS"
     CDS_motif       complement(7422..7544)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS2_0003"
                     /evalue="8.30E-17"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="curS2"
                     /protein_end="1016"
                     /protein_start="975"
                     /score="53.3"
                     /tool="antismash"
                     /translation="GIEPAMVMGHSLGEYAALHAAGVLSLADALYLVGHRALILQ"
     CDS_motif       complement(7731..7778)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS2_0002"
                     /evalue="1.40E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="curS2"
                     /protein_end="913"
                     /protein_start="897"
                     /score="17.6"
                     /tool="antismash"
                     /translation="FTGQGSHYAGMGAELY"
     aSDomain        complement(join(8073..8105,8168..8371,8428..9483))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS2_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.90E-135"
                     /label="curS2_PKS_KS.1"
                     /locus_tag="curS2"
                     /protein_end="799"
                     /protein_start="368"
                     /score="443.9"
                     /tool="antismash"
                     /translation="IAIVGMAGKGPGSDDLEEFWDVLLKGLDLHQEVPPDRYDLDEYYS
                     PKHPPAGPGKCTMTCRHGCFMNNPGHFDSKFFHISPREALLMDPAHRLFLMNAYEALEM
                     AGYSDGQTKMTDPTKIATFFGQCNDDWHVVGHRTLGCDAYTLQAVQRAFGPGRLAFQFN
                     WEGPTYALDSACAATSSCIHLACMSLIARDIDMAVAGAANVLSTPHSFTSLSRSGVLSD
                     SGNCKTYRDDADGYCRADFSGAVVLKRLDDAIAHNDNILAVISSSARNHSGNSTSITTS
                     DAAAQERLFHKVLRNARVTPEDISYVEMHGTGTQVGDKAEMGAVSSVFSKRRDGELLPV
                     GAIKANLGHSEAAAGMSSLLKSILMFQKGTIPPQAGMPHTLNPNFPPLHEINIKIPEEP
                     LEFKSVGGKPRRILLNNFDAAGGNACLLLEDY"
     CDS_motif       complement(8521..8568)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS2_0001"
                     /evalue="3.80E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="curS2"
                     /protein_end="689"
                     /protein_start="673"
                     /score="12.6"
                     /tool="antismash"
                     /translation="YVEMHGTGTQVGDKAE"
     aSDomain        complement(join(9850..10005,10069..10354,10407..10678))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS2_SAT.1"
                     /evalue="9.10E-55"
                     /label="curS2_SAT.1"
                     /locus_tag="curS2"
                     /protein_end="246"
                     /protein_start="8"
                     /score="177.6"
                     /tool="antismash"
                     /translation="LLFGDVTDPWVDGIDYVYSQAATTPWLRSFLRDLFTVLKVEMRTM
                     DRTLQESFRDCGSFQELAERYRHTGDDFGMAHAMLTYVIRAVVLLETISAEPHLLDSNR
                     PRPELIGVSGGLFSAAVVSVSTNFQSLYDTCLEAGRVWARLCNLTLVKSRAIEERPGTW
                     GWAVLGIPAGKLSQTLEQFQNDMGVPSAKRARVGVTGDRWSTVIGPPSILELVLNECPT
                     LKNLPKNELDIHALQH"
     mRNA            join(<13114..13467,13532..>15364)
                     /gene="curR"
                     /product="CurR"
     gene            <13114..>15364
                     /gene="curR"
                     /note="atcurR"
     CDS             join(13114..13467,13532..15364)
                     /codon_start=1
                     /gene="curR"
                     /note="putative cluster-specific regulator of
                     dehydrocurvularin biosynthesis"
                     /product="CurR"
                     /protein_id="AGC95322.1"
                     /transl_table=1
                     /translation="MSLSHVAPSHDAYGQAKRRKVRKGTHSCWECKRRKMKCRFDPRIA
                     SACNGCRRRGSPCISQEFPEDLEEAVMNIGTTSSDGTPFDGRTRATTPSERTDQILTPV
                     STVREPSQYPRSPEQHLPTGNDTSQRKYERLSRFLHELLPSRADRESIFKASRHSSILS
                     HELLTTPYITLHQNGLQTPESLLMTPQPNSHPVLIARYMLQFALFLQHLPPDLYKEIQG
                     LSEPPRATMERLADAAIYHVTTNEALINSIESLECIMLESLYQVNLGNLRRSWVAGRRA
                     MSLAQFMGFHRPDNQTRYYKALDPKTNYDPQIMWLRIIILDRQLCLLLGLPEGCTDHTM
                     ASSETRIANNCPMGRLEQLHCVAMSRILDRNASQPSGRDLTATRAIDLELQKAAGSLPS
                     KWWLAPKLDSASTDLQAMFWDTRRLVLQICHYNLLNQLHLPYMLRPSTAGNKYEYSRIT
                     CVNASREVLSRYNSLRSFNRIAYSCRTVDFLALMAAMALLLAHMDSYRDGAENLLANQY
                     LSDRGMIEQVQEHMSEINRLNSDELSAQSADLLKSLLAIDLEKGKGRVSVREAGSEGML
                     PQDGMGPEEESVVRVHIPYFGIIRIAREKQHATTASKPPVDRSPSSNSDAQLRFSTLTH
                     PSNALPLSPNTTSNPLSFAVADAAAPHEFTTPFAHQQQQPCQPTFSNPGLSLTPSPLMQ
                     GGYPDLAAGSEDWAFQRVDMAFFESIMRNVGGDL"
     mRNA            complement(join(<15611..15990,16114..16487,16573..>17534))
                     /gene="curE"
                     /product="CurE"
     gene            complement(<15611..>17534)
                     /gene="curE"
                     /note="atcurE"
     CDS             complement(join(15611..15990,16114..16487,16573..17534))
                     /codon_start=1
                     /gene="curE"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 307; E-value:
                     2.9e-93)"
                     /gene_kind="transport"
                     /note="putative dehydrocurvularin exporter"
                     /product="CurE"
                     /protein_id="AGC95323.1"
                     /transl_table=1
                     /translation="MADGSDLENNHKPELDRSQPGSTSNGSQEQKDPDEIAPEYATGVR
                     LILVMFTIFVSTILVSLEIGIIATAIPGITNEFRRLDDVGWYGSATFILAAAASPLWGK
                     LFKYVDVKWTYLSAVFIFLVGSIVAAAAPNSVSVIIGRAIQGWGASGVLGGTLIVINYV
                     APPRNHPLLIGTWMAVFMVSTILGPVIGGGFTSGVSWRWCFWINLPVGGPIIVLLLLFL
                     RIPKHIKKVPATWQEIILALDLPGFCLLLVSLVCLTLALQWGGQTKAWNDGSVIATLVM
                     WIVLSIAFLVTEWFQGQRAMTPFSILTLRMTWSNALFCLISYAALYQVMFYLPIYFQSI
                     HGQSAVKSGVNTLPFLAFFALGAVVSGGVIGKTRYTQPFELLGALIMTAGMALIYILDV
                     DSPQAMYIGAEVLFGFGVGICNQIPMTAVQGFSKQEDVSSATGIMVMCQTLSGAYFVAI
                     AQSLFANRMLATVLSGAGHLDPALVLGTGASELQHVFSGEDLTEVIAAYMVGIKDVFAF
                     SLACAAFAVLLSLIIPFKRLPDHGKKDKPATEEAAEEKSEAEGKVSGDKEENHS"
     mRNA            join(<18391..18511,18587..19318,19374..19468,19520..19630,
                     19687..22542,22610..>25858)
                     /gene="curS1"
                     /product="CurS1"
     gene            <18391..>25858
                     /gene="curS1"
                     /note="atcurS1"
     CDS             join(18391..18511,18587..19318,19374..19468,19520..19630,
                     19687..22542,22610..25858)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (12-434). E-value:
                     2.7e-168. Score: 552.1. Matches aSDomain:
                     nrpspksdomains_curS1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (551-872). E-value: 4e-96. Score:
                     313.7. Matches aSDomain: nrpspksdomains_curS1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (942-1129). E-value: 1.3e-23.
                     Score: 76.0. Matches aSDomain:
                     nrpspksdomains_curS1_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1672-1987). E-value: 8.5e-113.
                     Score: 368.4. Matches aSDomain:
                     nrpspksdomains_curS1_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2011-2190). E-value: 8.1e-52.
                     Score: 167.6. Matches aSDomain:
                     nrpspksdomains_curS1_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2297-2377). E-value: 2.3e-12.
                     Score: 39.0. Matches aSDomain:
                     nrpspksdomains_curS1_PKS_PP.1"
                     /codon_start=1
                     /gene="curS1"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 239.3; E-value:
                     1.3e-72)"
                     /gene_kind="biosynthetic"
                     /note="highly reducing polyketide synthase (hrPKS) for
                     dehydrocurvularin biosynthesis"
                     /product="CurS1"
                     /protein_id="AGC95324.1"
                     /sec_met_domain="PKS_KS (E-value: 3.9e-169, bitscore:
                     552.1, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.8e-97, bitscore: 313.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1e-48, bitscore:
                     154.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4e-18, bitscore:
                     54.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPSAQHSVGDVPIAVVGLSCRFPGDASTPSKFWDMLKNGKDAYSP
                     TSTRWNSDAFYHPGDGRLNSLPTKGGHFLKEDPYVFDAAFFNITAAEAIALDPKQRIAM
                     EVTYEAFENAGMSLQQISGSQTACYIGSGPSDYRGAVERDFLHNPKYHLLGTGDEMISN
                     RISHFLDIHGPSATVQTACSSSLMATHLACQSLRSGESEMAITGGISLMLTPDFTTHLN
                     NLTFLNPEGLSKAFDESAGGYGRGEGCGIIILKRLADAIQDGDDIRAVIRGTGANSDGF
                     TQGVTMPSFEAQAALIRQVYSSNGLDYSTQYVEAHGTGTKAGDPIETRAIYSTIGKGSP
                     KPRKLFVGSVKPNIGHLESAAGVSGIIKGILSMEHNLIPPNLHFTKANPAIPFDEWNMA
                     VPTKLTPWPVAATKRMSVSGFGMGGTNGHVVLESFDSTRSTNGSGYSGGFSTFEKTRTK
                     KRLFVFSSHDQAGFKRNANALAEHLDTVGSVASSSDFMANLAHTLSGARSSLSWRATCI
                     AENKIELRDYLTTKPGDGASRDATNATRAPRIGFVFTGQGAQWARMGVEMLDRPVFRDS
                     VAQSTHYLQAMGCVWDPVAELKKTQADSRLSQPEISQPICSVLQIALVDELRSWGVTPS
                     KVVGHSSGEIAAAYSIGALSHRDAIAAAYFRGVATVRLRADAPDLKGGMMAVGCSRDEA
                     EELIEQSKLDGTAAVACVNSPSSVTLSGDVDTLEQLRAICDEHKVFVRRLKVEMAYHSR
                     HMNRVSGTYAEFIADLQPIPREYNENEDDDSIQTMLSSVTGQEVAPELLGPYYWVRNLV
                     SPVLFSDAVKEMVAPDEAEGDNTVDLLIEIGPHGALGGPVEQILGHHGVKHITYKSMLT
                     RGRNALETSLELASELFLKGVPIDISQVNSDLNPRRLTDLPPYQWNHSKVFRHETRIQR
                     ELVMRQFPSKSIIGAQVPMMDESQHVWRNFLRLSDEPWIRGHKVGSTVLFPAAGLIGMA
                     LEAAQQLVEPSKTARSLRLRDISFFAAMALSEDVPTEVIMHLRPHLLATSGSTPAAWWE
                     FTISSCAGIDNLRDNCRGLITIDYAETTSEQMASEDASLEASRIAHYHRVREESSYTYS
                     KEDFYSQFEKIAWNYGEAFRGVEKVYLGDGQATYDVKLVDIGETASKGQLDRPFLIHAG
                     ALDSILQGCLGSTYRNGRFDMDKPVLPTFIGQMEISLDIPGDAGYVLPAVCESKRHGFK
                     ELSSNIYAFDSAVSKVNLSVVDYRVSELENDSGEQDSQQLEVDPAEITSEVRWNYALEV
                     LEPEEIKKVVLAVAAEDRVVELIRLYLHNNPAATVIELVPDYEALERATMSLLPPGTIL
                     PSHIKYAVAATGSKSENQVDIENVIGTPFDLGDLDDTLPTDIAAADLLVIPQSVNNHKD
                     LGVLLTRLTSFGKPDASLVLAVNSSVNVSNSMLESKGFRRVFDLENSVALYKSRQSGHT
                     NGHTNGHTNGTSTRSELFIIEPLATSSRINSFSGALQVTLREHGYPVFVTNWTEISARP
                     AADLEGNTFISLLELEQPLLDALSEPDFYSVRKLLLNSDRLLWITAGDNPSMGVVDGIR
                     RTMRSEVAGLKFQVLHLSSLDTALQCGPALAGRIMTTDTKDDEFQERDGMLQVARIFNS
                     PEGNEGVRRCLEDSVRVERLGEQERALRLTIMKPGLMDTLTFIEDDRMTGPLGATEIEV
                     DVKATGVNFKDIMAAMGLVEVSLIGQEASGIVTATGSTAASRFKPGDRVTLLWEGMHVT
                     KLRIDHRLAVHIPDSMSFEEAAALPMVHTTAYHALVNVAKLRPGQSVLIHAAAGGVGQA
                     ALQLATHLGLVAYVTVGSEDKRRLLMEKYNVPEAHIFHSRDTSFAKAIKRVTGGRGVDC
                     VLNSLSGELLRVSWTCLAPFGTFVEIGLRDITNNMRLDMRPFSRSTTFAFINIANFFDP
                     EGLDALGQILSDAFALVHKGVLGTAYPLTVYPVSELETAFRTMQQGKHRGKLVLSFGDN
                     AQAPVLCKARDSLRLSPKSTYLFIGGLGGLGRSLAREFVACGARHIAFISRSGDSSAEA
                     KATVQALTTLGANVKAYRADVSEEAAFLSAMQQCATDLPPIAGVVQMAMLLRDTLFEKI
                     SYTDWTQPMRPKIQGTLNLHNYFSATRPLDFFVICSSISGIFGYPGQTQYAAANTFQDA
                     LARHRRNQGLKGVAVDLGIMRDVGILAEQGTTGKLADWEAILGIREKPFHALMKSVINS
                     EWKGAVPPPAQLCTGLGTADIMARFGLERPEHFSDPRFGPLNVLSIESSSSLSTDQDTA
                     SSPSTRLAAATTLDEAVVIITDALVHKMAEILQMPLSEVDPGRPMYRYGVDSLVALEVR
                     NWITRELQANMALLEILAAEPMRVFAGKIAEKSKLVAGRKG"
     aSDomain        join(18427..18511,18587..19318,19374..19468,19520..19630,
                     19687..19929)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS1_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="2.70E-168"
                     /label="curS1_PKS_KS.1"
                     /locus_tag="curS1"
                     /protein_end="434"
                     /protein_start="12"
                     /score="552.1"
                     /tool="antismash"
                     /translation="IAVVGLSCRFPGDASTPSKFWDMLKNGKDAYSPTSTRWNSDAFYH
                     PGDGRLNSLPTKGGHFLKEDPYVFDAAFFNITAAEAIALDPKQRIAMEVTYEAFENAGM
                     SLQQISGSQTACYIGSGPSDYRGAVERDFLHNPKYHLLGTGDEMISNRISHFLDIHGPS
                     ATVQTACSSSLMATHLACQSLRSGESEMAITGGISLMLTPDFTTHLNNLTFLNPEGLSK
                     AFDESAGGYGRGEGCGIIILKRLADAIQDGDDIRAVIRGTGANSDGFTQGVTMPSFEAQ
                     AALIRQVYSSNGLDYSTQYVEAHGTGTKAGDPIETRAIYSTIGKGSPKPRKLFVGSVKP
                     NIGHLESAAGVSGIIKGILSMEHNLIPPNLHFTKANPAIPFDEWNMAVPTKLTPWPVAA
                     TKRMSVSGFGMGGTNGHVVLESF"
     aSModule        18427..25825
                     /complete
                     /domains="nrpspksdomains_curS1_PKS_KS.1"
                     /domains="nrpspksdomains_curS1_PKS_AT.1"
                     /domains="nrpspksdomains_curS1_PKS_DH.1"
                     /domains="nrpspksdomains_curS1_PKS_ER.1"
                     /domains="nrpspksdomains_curS1_PKS_KR.1"
                     /domains="nrpspksdomains_curS1_PKS_PP.1"
                     /iterative
                     /locus_tags="curS1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       18982..19029
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0001"
                     /evalue="1.50E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="curS1"
                     /protein_end="188"
                     /protein_start="172"
                     /score="17.1"
                     /tool="antismash"
                     /translation="GPSATVQTACSSSLMA"
     CDS_motif       19171..19209
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0002"
                     /evalue="1.60E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="curS1"
                     /protein_end="248"
                     /protein_start="235"
                     /score="8.7"
                     /tool="antismash"
                     /translation="FDESAGGYGRGEG"
     CDS_motif       join(19454..19468,19520..19552)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0003"
                     /evalue="1.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="curS1"
                     /protein_end="327"
                     /protein_start="311"
                     /score="13.7"
                     /tool="antismash"
                     /translation="YVEAHGTGTKAGDPIE"
     CDS_motif       join(19613..19630,19687..19713)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0004"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="curS1"
                     /protein_end="362"
                     /protein_start="347"
                     /score="11.3"
                     /tool="antismash"
                     /translation="GSVKPNIGHLESAAG"
     CDS_motif       20278..20331
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0005"
                     /evalue="1.50E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="curS1"
                     /protein_end="568"
                     /protein_start="550"
                     /score="17.4"
                     /tool="antismash"
                     /translation="FVFTGQGAQWARMGVEML"
     aSDomain        20281..21243
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS1_PKS_AT.1"
                     /evalue="4.00E-96"
                     /label="curS1_PKS_AT.1"
                     /locus_tag="curS1"
                     /protein_end="872"
                     /protein_start="551"
                     /score="313.7"
                     /tool="antismash"
                     /translation="VFTGQGAQWARMGVEMLDRPVFRDSVAQSTHYLQAMGCVWDPVAE
                     LKKTQADSRLSQPEISQPICSVLQIALVDELRSWGVTPSKVVGHSSGEIAAAYSIGALS
                     HRDAIAAAYFRGVATVRLRADAPDLKGGMMAVGCSRDEAEELIEQSKLDGTAAVACVNS
                     PSSVTLSGDVDTLEQLRAICDEHKVFVRRLKVEMAYHSRHMNRVSGTYAEFIADLQPIP
                     REYNENEDDDSIQTMLSSVTGQEVAPELLGPYYWVRNLVSPVLFSDAVKEMVAPDEAEG
                     DNTVDLLIEIGPHGALGGPVEQILGHHGVKHITYKSMLTR"
     CDS_motif       20518..20610
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0006"
                     /evalue="3.40E-10"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="curS1"
                     /protein_end="661"
                     /protein_start="630"
                     /score="32.4"
                     /tool="antismash"
                     /translation="GVTPSKVVGHSSGEIAAAYSIGALSHRDAIA"
     aSDomain        21454..22014
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS1_PKS_DH.1"
                     /evalue="1.30E-23"
                     /label="curS1_PKS_DH.1"
                     /locus_tag="curS1"
                     /protein_end="1129"
                     /protein_start="942"
                     /score="76.0"
                     /tool="antismash"
                     /translation="IGAQVPMMDESQHVWRNFLRLSDEPWIRGHKVGSTVLFPAAGLIG
                     MALEAAQQLVEPSKTARSLRLRDISFFAAMALSEDVPTEVIMHLRPHLLATSGSTPAAW
                     WEFTISSCAGIDNLRDNCRGLITIDYAETTSEQMASEDASLEASRIAHYHRVREESSYT
                     YSKEDFYSQFEKIAWNYGEAFRGV"
     CDS_motif       21529..21606
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0007"
                     /evalue="3.60E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="curS1"
                     /protein_end="993"
                     /protein_start="967"
                     /score="32.3"
                     /tool="antismash"
                     /translation="WIRGHKVGSTVLFPAAGLIGMALEAA"
     aSDomain        23711..24655
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS1_PKS_ER.1"
                     /evalue="8.50E-113"
                     /label="curS1_PKS_ER.1"
                     /locus_tag="curS1"
                     /protein_end="1987"
                     /protein_start="1672"
                     /score="368.4"
                     /tool="antismash"
                     /translation="GLMDTLTFIEDDRMTGPLGATEIEVDVKATGVNFKDIMAAMGLVE
                     VSLIGQEASGIVTATGSTAASRFKPGDRVTLLWEGMHVTKLRIDHRLAVHIPDSMSFEE
                     AAALPMVHTTAYHALVNVAKLRPGQSVLIHAAAGGVGQAALQLATHLGLVAYVTVGSED
                     KRRLLMEKYNVPEAHIFHSRDTSFAKAIKRVTGGRGVDCVLNSLSGELLRVSWTCLAPF
                     GTFVEIGLRDITNNMRLDMRPFSRSTTFAFINIANFFDPEGLDALGQILSDAFALVHKG
                     VLGTAYPLTVYPVSELETAFRTMQQGKHRGKLVL"
     CDS_motif       23801..23836
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0008"
                     /evalue="6.00E-04"
                     /label="PKSI-ER_m1"
                     /locus_tag="curS1"
                     /protein_end="1714"
                     /protein_start="1702"
                     /score="12.8"
                     /tool="antismash"
                     /translation="GVNFKDIMAAMG"
     CDS_motif       24023..24067
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0009"
                     /evalue="2.30E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="curS1"
                     /protein_end="1791"
                     /protein_start="1776"
                     /score="11.5"
                     /tool="antismash"
                     /translation="AAALPMVHTTAYHAL"
     CDS_motif       24092..24154
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0010"
                     /evalue="8.00E-10"
                     /label="PKSI-ER_m5"
                     /locus_tag="curS1"
                     /protein_end="1820"
                     /protein_start="1799"
                     /score="30.9"
                     /tool="antismash"
                     /translation="GQSVLIHAAAGGVGQAALQLA"
     CDS_motif       24176..24214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0011"
                     /evalue="2.60E-03"
                     /label="PKSI-ER_m6"
                     /locus_tag="curS1"
                     /protein_end="1840"
                     /protein_start="1827"
                     /score="10.8"
                     /tool="antismash"
                     /translation="YVTVGSEDKRRLL"
     CDS_motif       24293..24331
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0012"
                     /evalue="1.70E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="curS1"
                     /protein_end="1879"
                     /protein_start="1866"
                     /score="14.1"
                     /tool="antismash"
                     /translation="TGGRGVDCVLNSL"
     CDS_motif       24608..24655
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0013"
                     /evalue="2.60E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="curS1"
                     /protein_end="1987"
                     /protein_start="1971"
                     /score="20.2"
                     /tool="antismash"
                     /translation="AFRTMQQGKHRGKLVL"
     CDS_motif       24728..24826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0014"
                     /evalue="4.70E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="curS1"
                     /protein_end="2044"
                     /protein_start="2011"
                     /score="48.1"
                     /tool="antismash"
                     /translation="TYLFIGGLGGLGRSLAREFVACGARHIAFISRS"
     aSDomain        24728..25264
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS1_PKS_KR.1"
                     /evalue="8.10E-52"
                     /label="curS1_PKS_KR.1"
                     /locus_tag="curS1"
                     /protein_end="2190"
                     /protein_start="2011"
                     /score="167.6"
                     /tool="antismash"
                     /translation="TYLFIGGLGGLGRSLAREFVACGARHIAFISRSGDSSAEAKATVQ
                     ALTTLGANVKAYRADVSEEAAFLSAMQQCATDLPPIAGVVQMAMLLRDTLFEKISYTDW
                     TQPMRPKIQGTLNLHNYFSATRPLDFFVICSSISGIFGYPGQTQYAAANTFQDALARHR
                     RNQGLKGVAVDLGIMR"
     CDS_motif       25109..25219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_curS1_0015"
                     /evalue="3.40E-22"
                     /label="PKSI-KR_m4"
                     /locus_tag="curS1"
                     /protein_end="2175"
                     /protein_start="2138"
                     /score="71.1"
                     /tool="antismash"
                     /translation="LDFFVICSSISGIFGYPGQTQYAAANTFQDALARHRR"
     aSDomain        25586..25825
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_curS1_PKS_PP.1"
                     /evalue="2.30E-12"
                     /label="curS1_PKS_PP.1"
                     /locus_tag="curS1"
                     /protein_end="2377"
                     /protein_start="2297"
                     /score="39.0"
                     /tool="antismash"
                     /translation="TTLDEAVVIITDALVHKMAEILQMPLSEVDPGRPMYRYGVDSLVA
                     LEVRNWITRELQANMALLEILAAEPMRVFAGKIAE"
     mRNA            <26407..>27078
                     /product="putative metal-dependent phosphohydrolase"
     CDS             26407..27078
                     /codon_start=1
                     /note="orf2"
                     /product="putative metal-dependent phosphohydrolase"
                     /protein_id="AGC95325.1"
                     /transl_table=1
                     /translation="MCAPLHPEGRPNTASSWPKEIPNMLPPDKIAQGAYDLAKSILPES
                     IFNHSIRVALLAKWLAERERSEWASPGKLSLLAVACLLHDVGCAHQFDGAQRFEVEGAD
                     AAASYLRQHEIPKSDIHEVWQAIALHTSPGIAERISSCARLVRQAVLLDFGKSLDQESQ
                     AFRQHIEESFPRIGIEKVLGDVVVDQALRQPQKAPPASWPGILLRAKQDNPEWTGVNKA
                     F"
     mRNA            join(<27478..27639,27697..27923,27978..>28101)
                     /product="hypothetical protein"
     CDS             join(27478..27639,27697..27923,27978..28101)
                     /codon_start=1
                     /note="orf3"
                     /product="hypothetical protein"
                     /protein_id="AGC95326.1"
                     /transl_table=1
                     /translation="MSRKPVLKVATWLHILLRILLLLSGIALLALAVYMAVRWGPITSR
                     KIYPGALTAASLSIITDIIAIILPISKLDYIPTVVFFEIATLVVGLWGLFSLLFSDYSY
                     SNAPHDNPTGWQHMNGITLAFAIVLVCERTISLTAVCISCCRQARKRKRAKRQARTQAN
                     GHVNDAI"
     mRNA            <28731..>30911
                     /product="putative glycosyl hydrolase"
     CDS             28731..30911
                     /codon_start=1
                     /note="orf4"
                     /product="putative glycosyl hydrolase"
                     /protein_id="AGC95327.1"
                     /transl_table=1
                     /translation="MTQSAVYTFHDALAAIKSGKPLAQVTQTLLSQLSKDERLALLDGD
                     VEFWPGLGSILRDRYNRTPYVHGAVPRLHIPGIRFTDGPRGVVMRNSTAFPVSMARGAT
                     WDLELERRIGDAIGLEAKAQGANYFAGVCVNLPRHPAWGRIQETYSEDPLLLGEFGLAL
                     TQSVQKHVMACVKHYALNSMENARFRVDVSVEESVLHEVYLAHFRRIVEGGVAAVMSAY
                     NSVNGEWAGQNKHLLTEILREQWGFDGLIMSDFIFGLRDAEKSVTNGLDIEAPFRQQRA
                     MHLGAALERGDLSWVDVDRSCERILRKELEFAVKTEDSQPGADVIFCAKHRALAREAAA
                     RSMVLLKNNPVDGGPVLPLQATSLSRVAVVGRLANVANTGDKGSSQVFPPGVVTPLEGI
                     RAALPGVEVLFAVSQKEAETLASQVDAVICIVGYDHEDEGEYVIPALLENPALQNVLPP
                     PRNDEERETLAILQGQLNPGSEGGVEAGAGGDRVSLRLRQEDEDLIAAVAARNPRTVVS
                     ITTAGAVIIESWKNKVPAILMSWYSGCEGGHALADILLGKTDASGRLPFSIPVEGAHLP
                     YFDRDASKISYDRWFGQHLLDKLGVEAAFPFGFGLSYTTFNVSEVAVRREDPEHIQVQF
                     VVRNTGERPGRFIAQVYGLPGCEDFPTRLLLGFTPVDLEAGQEMNCQVSASLRPLQRWK
                     DGEYSLRTRELGVEVARFAGDDEAARARTVLA"
ORIGIN
        1 cctctcacgc tggatgaact acgttgcgct ctcgccgtcc aaaaccagag agacgacgat
       61 cgtgcggtga actatgacta tgcccccaat gacatggata gagtgatatc tctctgtgca
      121 ggacttgttg ttgtgaacca cggaagtcgc acagtagaat ttgtgcatca cacgactcag
      181 caatatctag agggaaacca aagccaacat ccctggttgc atcgatacgc cgaagacatc
      241 gcccggactt gtttcaaagt gctgtcctct ggcatttttg acaccataca agagccacga
      301 agttgcgatg cagatggaat agtcctctcc cacccattcc tcgactatgc ggcacaatac
      361 tggcctgatc atgcccggga aattcagaca aatgcagcta cgcagaacgc tgcccggaat
      421 ttcctcttga acccccggct taccagcttt gcggaccata tttatcgtcg aagggactat
      481 gaatacctca gtctttgtag atatcgctat cgagaggtgc ctgtccctca aacccacggg
      541 ctgcaccttg tggccaataa attcacatag agccgaacca ggatgaacct aggagtataa
      601 ttatttcaac ggaacattca gcttcggtat atttgtaaac ctacattcca ttggcggccg
      661 aatgaattat ccctatgatt cggtcaatgt ttattccccc gtgtgtaatg gtggccaggt
      721 gctgttgaat gaacgctgcg acgtccgttc tctctgcgcg gatctccatt ttggaaaaat
      781 cccgagcctg tctaaactcg gtggtgattc ggtccacatg gcgagaagtt agcaatattt
      841 ggaccccagt cttctgcagg caccagagaa cgcccaggaa atcggacaga tgggggggcg
      901 agcactcatc cagggcatcg acaatgagaa ataccggtcg atcctggctg gataacatcc
      961 gttccatggt atcctctatc tccgccaagg tcgggcttcg ggatcctgct ctgcacaggg
     1021 catagagaga cttgatgggt tccggaatag aggatagatg agtgacttgt cttagaatgg
     1081 agcgcaagat gacgtctgaa gtctgctgac cggagagttt gtagttaaaa taaatacatg
     1141 ccacaatggg tccgctgaca ctgttattct cgcggagata atctgtcact gtggaggcaa
     1201 gagtggtctt cccagcccca gggagccctt gacacaggag gatttgaggg gatttgcctc
     1261 gttccatcca gttcaaaaat gtcggatgcg ttaaaaacca tctgcaagtg cctcttgttc
     1321 gcttcatgcg gatatcatcg tgttggcctt catggaacgc aggcgccaac caatctagaa
     1381 ctgcctgcga ttcctgaagt tcatttcctg cgagaagggg ttggatgtcg cgacgaagct
     1441 cagcagccga ccggtagact gtggattcca ttaatcccgt caaatttcgg gcgatcacct
     1501 ttcgggttcc ttactcacgc tttccatgct gttggcggcg gtaggcgtct gttgcatgtc
     1561 gaaagcaggc atcacctcca ggagctcctt ggtaaacgct gaggcagtcg ccgccgcata
     1621 gtcctgccag tcgtctgctt tgtgactatc cgagtagtcc gaaatgcctc ggataatgag
     1681 acaggggaag ttgctcatca agccggccgc ctccatttca aagcagagca ttccatactt
     1741 ttctcgtagc gcatcgcgtg tttttgagtc gcgcataaca ttgttagcag aggcgatgag
     1801 accatagtgg actgccgggt ccgatgtacc tcgtttcgcc cgcttgacga ctctttccgc
     1861 cctcgttggg catcccagtt ccgcacatgt cctgcctcgg ccggggtgtg ggaaatctga
     1921 ggcatacagg acgtcgcact ccgcgccggg atattcccat ctggaggcca ttcttggata
     1981 cctatggcgc attgtttgaa tacatttcgc gatggagtta ccctggaggt catggcggct
     2041 ccgcaattgc gaaagtgcgg tgagtagtac atctggaggt cgctgaagat accctgtcgt
     2101 aacgaacgct ccatcgtggt aagtcttgcc aaagtcgtat tggatgacac ccccttgctt
     2161 cagttaggtg gtgtatgtat atcggagtgc aacggcacgt tgggtactga ccgtgcccat
     2221 cgccaggctc actgacaact acatctccca gtctaacctc cttctctgga ttgtgactcg
     2281 gtggtcctgg cacaccaccg ccgataccga caaacaaacc cacgcggata tgagggaacg
     2341 ttcgaagcat atcctttgct actgcagtcg ctgctgctgt tcccggtgtt cccgcaggaa
     2401 gctgtgcaat gaccacgttg tgctcgccaa tgcgtccggg ggtgtaagcg ttggaatcgc
     2461 ctgggacacg gcctatccga tcatactgtt cgtccaagac cgcagtcagt gcagttgctt
     2521 ctagtgattt ggcacagagc aatccgatcc aaaagtcgga atatgtgcga tcgctcggcc
     2581 tgtacgaggt cagcacactc aagacgcgcg aagcggtcca atcccagccg ccggagccta
     2641 catggtgctt cccaaatatc tgcaagaatg ctagagcggt cagggcgcgt tgattgtgtc
     2701 tctgtatgac aggctaccag gtacatgttc gagcgaggca cgtttctcca agccgaacca
     2761 cttctaaccc tggcgcagag ggcttgtcct gaggaatttg accctcttac tcgggccacc
     2821 ttgctgttca acttgggagg gatacgtttt gaatgtaaca gagtgagcga gtctctcgac
     2881 ctctgcagaa agtcccttga cctgcggagc cagcatctcg ccgcggacga ccctcttctg
     2941 ggcaacacat acttttctct cggaatcatc tacatggaaa gtggagacct gcaaaagtca
     3001 ctggaacata atcgaaaagc cgttgagata caggagagct cgcagagaca tgatggctcg
     3061 ccacttgcat gggcacacgc caacttggga ctgtgttact ggaagatggg agagttcgag
     3121 ttggcgtcag aatggttaac aaaagcccaa cagtgctttg gcatggaaac caaatggtcc
     3181 cagaaatacg gacagtatgg tctcctgtac cccccctgag tgatatggtt cgggcgctaa
     3241 acttgacagg gtcctgtatt atatcggaaa cctaaagcta tcccagaaaa agcacaaaga
     3301 ggctcgggac gcgcatgagc agtccctgaa gattgctcaa agcattacac ctggtcattt
     3361 caagacaggc cttggattcc ataagatggc cacatttttt catgatgaag gtcaccacga
     3421 gatggcgatg taagtagtac acttttccct cccactccac gtcatcccag ttcatcgatt
     3481 ttcaaggcaa tatttacaac gagccatatc aaattttgag ggcacctttg acgccgttcc
     3541 tcgtatcgct cgttcaaagt acaaaatgtc tgaggtacta caggcactcg gcaggaggga
     3601 ggaggcagca gcaaaacggt tggaagcaga gcgattgcga gagagcatta cgacgtttgc
     3661 ctataaccca gaatcatcgt tggaggcttt cgatgcactt gtgccatcct tcttggctta
     3721 actatgtctt cggggaacac cgtggtcttg tcgttgctga cagtcactgt tgattagtct
     3781 ttttcgactg tatcgcatta tgtatcatta cacacttgac tgtatatatt agattcgaga
     3841 ggagcttggc tcattctgat catgaatatg taggaaaagg tttgggctta gaggctcgag
     3901 gctgtcttcg gaataacaat agcacggatt caggtaggtc atcgagcatg aggattctca
     3961 atatcatttg aaggctcggc tatcttgaat gaatctctgg ggaatacgaa tatcattatt
     4021 tttgacctac atcgcatcaa aaagaaagaa aggtcctatc ccatcgtagg atttatatcc
     4081 tgactttggc caatacacag ggtcgtatta ttctattacg aagtccctat gtacatctat
     4141 aacaatcatc tgatatacat cattctctgc tgacttgctc caagaaggag cgatatactg
     4201 cttcctgcac accctagtta ggtagactcc ccctcaaaat atgcaaacgc cttctccatc
     4261 tccctctgca gcaagtgcac atgtcctggc atgggcaaat ccaaatgatc cccagccacc
     4321 gacaacgcca acacctcccc tgccgtatac ttctcccacc cgttcggtcc caaatccgcc
     4381 gccgtccgat ccggcaccaa acacgcaaac gcccccaacc gcggatcctc catgtacccg
     4441 gggtacgacg tggtcgggat gccctgatcg gccaacatct gcatcagccg gtcattcccg
     4501 accacccgat tcaccatgcc cttctccgcc cagataacgg ccgtgtggct ggggcgttcc
     4561 tgcgccgtca tgtacggcgg gtggtacgcg tgcatggcga catggtacgc gcggaaatgg
     4621 tcttgcgtcg tgctagccag gctccacagg ccgtctttgg acacggcgtt ctcgaagatg
     4681 gcgaagctgg cgtcgtcttc gctgttcatt gcgtcctcgt cgaggaggct ggaccgtgga
     4741 cagcacatgt cgatcaggac caggccggtc acctgtcgac cgagcgcacc gagttgccgg
     4801 gtgacttcgt aggcgacgat cgagccggcg gagaagcctc cgatcatgag aggcccggtg
     4861 ggttgggcgg tgactagggc gtcgacgatg agctttgcga cgccggggat gccgacgtct
     4921 ttggtgagac ggcttgggca ccggaggaaa ggtgagtcga tgccgtacac gggcattttg
     4981 gatttgaagg cgggcaggtg gatgtacgtt gctattgtgc cggtgccgtc ggccatcatg
     5041 tagaaggggg tccgtttggg gctgggacgg ccttggagga gggtgatgcg gacggtgggc
     5101 gctggggatg tatcggtttc gtccatcttc cccaggtggt ggttgggctt gggctccaat
     5161 tccggagggg gtgtgaaggt ctggtccttt tcgatgtcga cgaggctgga cccgagcgag
     5221 gaagcggtgt cggacatgga cgtgggctcg ggattggggc tcgatgggat ggaggactgg
     5281 gagctggagg gggttgttga gccaggctgg ggcttgctcg tcttgggttt gttggctcca
     5341 aaggcgcggc ggaggtcgcc gattgtggga tgctcgagga cgaatgttgc cgggaggtcg
     5401 aggccggatt gctccttgac ggtggcgacg acctcgatgg ccatgatgga gtcgacgccc
     5461 aggtcggcga cgatcgtgtc gtcggtgaac tcggaggggt cgctgccggt ggccttggag
     5521 atgctgtcca agatcgcatc gacgagtcct tcgtcaaagt catcatcgtc gtcctcgcct
     5581 acctcagccg gttggggctg cactggcgcg acggccacag cttgccgact gacctcgacg
     5641 gctttcttgg tctcctgcac aggtgcttta tggccatgcg ccgaagaacc cccatgcggc
     5701 ccatcaagaa catgcttcca ggtcacccgg gggagttcct gataccggag gtcaatacat
     5761 tgcaggatga tatttgacgt ctccggatca aacaccaccg catcgcagta cgccgtctcc
     5821 ttgacccatt tggagatccg agtatacgcc atatacttct tccccggcac caatgggacc
     5881 gtctgctcga cactctcgaa acccatcaca atgaaggtct tctgggggga tttgctgggg
     5941 ttcccattca ccatgaagcc cgcgaggtgc accagtgcct caccccaata cggggagaag
     6001 gtgaacttgg tcccagccgg atcatgcggg agtgtcacaa gcgcggccgc ctcctggaag
     6061 tctttggcaa tgtatgcctc gtcgacgccc tggaaatccg tgctgaactc gactgcattg
     6121 gcaaacagcg catagaagac ttcaggctgc atccggtggc ccggtccctc tttcgcattc
     6181 ttgatcacct cgtccatcct ggcttggatg aagtacgaga cccggtccca gtcggcctgg
     6241 gtcttggctg ggtcccggaa attgacgatg caggagccga gctcgtgtga ttcgcttccc
     6301 gatgtcagct tgaatgtcac cgagatgcgg tgtgcagacg gagagtccat cacggcggtg
     6361 gtgatgagac ttccatcggc gcctgcgagc ttcttggtaa ggggcaggag tagctcgggt
     6421 ttctgaaggg tgagccaggg ctgcgtcaca ttccttctac cgctgtactc gagggcatac
     6481 ttggctgctg caaacgcggc ctcgcagaag acactccccg aacacagtcc gatcccctgc
     6541 atcttgtgac cgtcaataag ttccataaat cctggatctg agatggaggc gcggaaaacg
     6601 acctgcacct tcggcgagga cgacttggag accagatact gtgcgcaggt cgagacgagc
     6661 ggcccggacc cagtgactgg agactgctcc ggcacagcct cggtgactcg gtcggtatgg
     6721 gtgatccagt agtccttgac atcccacgca taagacggca gggtcaacaa ctgcagattg
     6781 gtctcgtacg gcgcgtggag tgcgacccaa tcgatgtcga cgccgttgat gtaagccgcc
     6841 gcaagagatt tggaaatgga tgcccagttg tgggtgtttg gttgcagggt atgcgtgagc
     6901 ttggaaaggg aaggggacag cgtgtcgcgc acgaacgata cgcacaccgg ggatggtcca
     6961 atttccagcc agagagggtc actcagtttg gactggacgg cgttgagacc gccaacaaag
     7021 ttgaccggtt gacgggtctg ctggaccagg tagtcgtggt cgaagacacc cggttccccg
     7081 acgatggatc cgagcagagt tgatgccacc gggattttcg gcgccgagaa cgtcacacct
     7141 gcggcaatcg tgccatagtc ttggaggatt ggatccatct ggaaggaatg gaatgcaaat
     7201 gggatggaca acgtcttcgt gcggaccttg gcatcttgcg ccgtgatatt tgcctggaat
     7261 tcggccagat cctcggcgat tccactgacg acagtagaac ttgggctgtt aatgcaggcc
     7321 acaccgcagg acgaggactg gagctgggaa agctgctccc gcacatttgc gacggaagtt
     7381 gacaccgaaa gcatggagca cgacccagat tcgcatcgct cctggaggat cagggcccga
     7441 tggcccacca ggtacagagc gtcagccagc gacaggacgc cagccgcatg gagtgctgcg
     7501 tactcgccca gactgtgacc cataaccatc gcaggctcaa tccctgccaa tcgccagaag
     7561 tgggtgaggg ccatctccag ggtgagcacg gcgagttgca cctgcgccgc agtcttggat
     7621 gacacatcaa ctccctcgtc ggtaatgatg tccacgaagg gggcgaagtt gttgccggcg
     7681 cagatgtcca cacacaaatc gaccctctcc cggaaggctg aactggtgcg gtataactcg
     7741 gcccccatac cggcgtagtg agatccctgt ccggtgaaga cgaagacgac agggacatga
     7801 cgcgaggctg gcgagttggt attgcgttcg atctcggact ccagtttgga aatggcctct
     7861 tgtgtcgttg atgcagtcag cgcaaatctg atcggatggt gcatccgtct cgctgtcgtt
     7921 gtataggcca ggtcctcaat ccgagtgttg gggtttgatc ggagccactt gagaagccgt
     7981 tgtttgttca ggaggtgcga ggcctgggtc cttgccgagg tgacgatggt gtgcgccgac
     8041 ctcacatccg cttctctctc tttcgtatgg gtgtagtctt ccaggagtaa acatgcgttg
     8101 ccgccctgga gtttcatata cattattagc acagcagcgc tgcggcggga gcatatggac
     8161 gacttaccgc ggcatcgaaa ttgttgagaa gtatacgtct cggcttgcca cctaccgact
     8221 tgaactccaa tggctcctcg gggatcttga tattgatctc atgcaggggt gggaagttgg
     8281 gattgagggt atgaggcatc ccagcctgtg gtgggatggt ccccttttgg aacataagga
     8341 tgctcttgag cagggaagac attccggccg cctggatgac tttagcatct gcacacgtaa
     8401 ttgccgtgtc tgggacgagt tactcactgc ttcactgtgg ccaagattgg ccttgatagc
     8461 cccgacaggt agaagctctc catcacgcct cttcgaaaag acactagaaa cagcgcccat
     8521 ctctgcttta tcgcccacct gggttcccgt tccatgcatc tcaacgtatg agatatcctc
     8581 aggagtcact cgtgcatttc gaaggacctt atggaacagc cgctcctgag cagccgcatc
     8641 cgacgtcgta atggaggtcg aattccccga atggttccgg gccgatgatg agatcaccgc
     8701 caggatattg tcgttgtgag cgatggcatc gtcgaggcgc ttcagcacca ccgccccact
     8761 gaaatcagcg cgacagtacc catcagcatc atcacgatac gtcttgcaat tccccgagtc
     8821 agacaagaca cccgagcgac tcagactggt gaatgaatgc ggggttgaca gcacgttggc
     8881 ggctcctgca acggccatgt cgatgtctct ggcaatcaga ctcatacagg ccagatgaat
     8941 gcaagaactg gttgctgcac aggccgaatc gagcgcatac gtcggcccct cccagttgaa
     9001 ctggaaggcc agtcgccccg gtccgaacgc acgctgcact gcctgtaacg tgtaggcatc
     9061 gcatccgagt gtgcgatggc ccacgacatg ccaatcatcg ttgcattggc cgaagaacgt
     9121 cgcgatcttg gtcggatccg tcattttggt ctggccgtct gaatatccgg ccatctcgag
     9181 ggcctcgtag gcgttcatca ggaacagtcg atgcgcgggg tccatcagca gggcctcccg
     9241 aggcgagata tggaagaatt tcgaatcgaa gtgtccggga ttgttcatga agcagccgtg
     9301 gcggcaggtc atggtgcatt tgcccgggcc ggcgggggga tgcttggggc tgtagtattc
     9361 atccaagtca tagcggtccg gcggaacctc ttgatggagg tcaagccctt tcaagagcac
     9421 gtcccagaat tcttcgaggt cgtcgctgcc gggacccttt cccgccatgc cgacgatggc
     9481 gatcccgtct cgactgtctg gggttggtgg cttcgcagtg atcctatcct ggagggaaac
     9541 ttctcttccg gcggtttgca gcaccttggc aatatatgct gcgtggctgc tggggcccat
     9601 tatcttgaaa tcaacatgcg ttgatgtccc cagagcggcg ttgagcttgc tgacggcttg
     9661 cacgatgttc aacggccgtg ctaaggtctg tgatgctgag gctctcagga gatggctcca
     9721 gctggggtaa gtagcctcgg gacgatcgtc atccaggcca tatatccgat acccctgggg
     9781 taaaggtgtg tctagaaggg aggaatcccc gacgatatag tcaatatcgg cattggagat
     9841 gtctagggtg tgttgaaggg catggatatc gagctcgttc ttgggaagat tcttcaatgt
     9901 agggcattca ttcaatacga gctccaagat agagggagga ccgatgacgg tgctccatcg
     9961 gtctccggtg acaccaactc gggctctttt ggcagatggg actccctgtt gagccttcgc
    10021 gttagcttgt cattggggac taagagacgt gggtaaaggc cctcctacca tgtcattttg
    10081 gaattgttcc agggtttgac tcagctttcc agctggtatg cctaggactg cccagcccca
    10141 ggtcccgggg cgctcttcga tggctcttga tttcaccaag gtgaggttac agagtctggc
    10201 ccatactcga cccgcctcga ggcaggtgtc gtaaagagac tggaaattcg tcgagactga
    10261 cacgactgca gcactgaata gacctccgga gactccaatc aactccggtc tgggccgatt
    10321 cgaatccagc aagtgtggct cggcgctgat ggtccttgaa gttgtcaggt cagcagtgct
    10381 tcggcacaac acagcagagc acatactcta gtagaaccac ggctctaata acataggtca
    10441 gcatggcatg cgccatgcca aagtcgtcgc cggtatgtcg ataccgctcc gcgagctctt
    10501 ggaaactgcc gcaatctcgg aaactttctt gcaaggtgcg gtccatcgtt ctcatctcca
    10561 ctttcaggac ggtaaagagg tcccgcagga acgaccgcag ccatggcgtg gtagcagctt
    10621 gactgtagac ataatcaatg ccatcgaccc atgggtctgt gacgtctcca aacaggagaa
    10681 cggcaggacg gttggagtcc attcctcgtg ataggagaaa ctcaacgaaa ggttataact
    10741 tctaagaagg aatacagtac aacagtgaat ctactgcgaa catctccagg agagtaacca
    10801 cccaaatatt tatacccacg gaaccggtgc aacaaccccg acgaacgtgc gagattctca
    10861 tctgagcgtg gacggagaac ggagaagatg tgcgcaccgc agtttctggt gcaatggctc
    10921 gacccgtata gcgacattgt cctcatacta ggatagtgtg gggcggcgtt gcagctgcca
    10981 aagctgcatc gcgacaatcg gttggtgcaa tcttcgaaag ccctaactac gatacccgtc
    11041 agcccgtcgc gcctcgtata tccccccacc cgacctccat cttcagcaca tgcgctctcg
    11101 gaaacacccg aacgggagaa cccacgcctt ttggactcat tctccgtacg gcggaggccg
    11161 tttctcggtc gaattcgacc gaacaccgcg tgggccggac tcgggcaggc tcgtgatgcc
    11221 tgctgaggga ttcacatcca tggatactgt agagaggctc gaatgcccgg ggcccactgg
    11281 cggtgattat agatggtgtc atctcgactg tagcctcggg tggtcttatc aattcgggtg
    11341 gatgacgcgc acgctgatgg acgcatctgt aagctttgcg tagacgggaa ggattgtagc
    11401 ttcgatctct actggctaga gatggacgtt ctcagttacg tactataaat acgtatatat
    11461 tggtattctg ctggtattga ctgtcaggcg agcttttaac atgatatagg atgttctttg
    11521 ccactcgggg gcacggaaaa gtcgtagctt gaaagatact cagaatatac ccccgattgg
    11581 ttcctttggg ggtcggcgac agctggatga gaaaccaatt tctcggacac ctgcaatttg
    11641 agtactttct tattcgagca tacctgaaag ctatcatccc gagtctgatc ggaatcgacc
    11701 taggtagacc cgagagtgga caaatcacct gactcggccg tttacagcct ccctgcgtga
    11761 tcttattggt gcgggtggga tccatgctgg cgtccgcttt tgcagaaaac ggtcattctg
    11821 gctcttcagg ctgaggcctc ccacctctat acgcggtaga ttcggtggtg tagatgattc
    11881 ctatcggacg gtttgccatc tacatggctt ggcgccaggt tgaccaagtc tgttgatcaa
    11941 ggcgcgtcaa gtgtgctctt ggcgtcataa tattcaactg taggatccac gggttgtgac
    12001 atcgcaccct tcgcttgcgt gcggtccaca ggccctgcat attggcagat tcacgctctc
    12061 ggctggagta agcgagatac cggcgtattt tagccggttt acctgtgcgc tccttgcgct
    12121 tcttccgcgg aagccccgtc gaggggttcc cttcccccca tcatcttgct ctttgcatct
    12181 ttccttttcg gtcgacgttc gtaggcgtcc atccgggagg aggtatggtc atttcggtgt
    12241 tgttatcttc cttcgtgggt tagggtctga tgcactgatc ttgggcatct ggtcgttccg
    12301 gtagtggcta tcgttgccca gcagttggat gccgccgtgg ctttctgcca agtggctttc
    12361 ccgttcggta atcttccgcc ggtctcagca atcgtgataa atcctcgcat caatcgtggg
    12421 tgactcagga tacgagagcc gtctccccac tgcggtcgag gggtcattgg ttaagacctt
    12481 gattaataat gttccgggac caggttgttc gtgccccgta cgaggttgtg ggccctttca
    12541 ggttgagatc tccgccgggt ggacccgcgg gccgccttta gctccgctcg gagatataat
    12601 caacactcct caatatcaca tacaacagag tacgatgtag taccatcacg cgttccttcg
    12661 caaaccaaaa tgccaaggtg ataagctctg cagcagccgt gtttgccact cccaagccgt
    12721 agtgggtttc ggtctcacgc caagccagac ttaccagaat gctattcgat taggttcctt
    12781 cgcacagacg gtacccggtc tcaacccctg gttgaatgtt cgcgatgacc aagtcaatat
    12841 aaagctgctc gtaatcgatc gctcttaaag ttatgcccag tccgatacca gcgatggctt
    12901 cgcagaatac atcccgaagg agaatcgagt tatcatgagt accctgtcag aaggagcgca
    12961 attaccgcgc ttacggtggc aaaaacagcg gactgcgtta gttatccgtg gggatgacta
    13021 atccctcagt atctctcccc tcttcaaccg tcacgttgat cctccctcca ccacacgtct
    13081 ccatcgcctt ctccttctcc atgtctcttc accatgtcgc tctcgcatgt tgcaccgtca
    13141 catgatgcct acgggcaagc caaacgtcgc aaggtccgca aaggcaccca cagttgctgg
    13201 gaatgcaagc gccgcaagat gaaatgtaga ttcgatccgc gcattgcgag tgcctgcaac
    13261 ggctgtcgac ggcgcggctc cccctgtatc agtcaggaat tccccgagga cctcgaggag
    13321 gctgtcatga acattggaac cactagcagt gatggcactc cttttgacgg ccgaacgcgc
    13381 gccaccacgc ccagtgagcg gacagaccag atcctcacgc ctgtctcaac agtcagggag
    13441 ccttcgcaat accctcgatc tcctgaggtc tgtcttttca agccatttta tctttcccat
    13501 tcttgtagga ttgtcactga ctgcgttcca gcaacacctg ccgaccggaa acgacacatc
    13561 ccaacgtaaa tatgagaggc tgtcccggtt cttgcacgag ttactcccat cgcgagcaga
    13621 tagggagagc atcttcaaag ctagtcgcca ctcttccatc ctctcccatg agttgttgac
    13681 gacgccatac ataaccctcc accaaaacgg cctccaaaca cccgaaagtt tactaatgac
    13741 cccacaaccc aactcacatc cggttttaat tgcgagatac atgctccagt tcgccctgtt
    13801 cctccagcat cttcccccag atctctacaa ggagattcaa ggcctatcag agcctccccg
    13861 cgctactatg gaacgcctag ccgatgcggc catctaccac gttacgacaa atgaagccct
    13921 aattaacagc atcgagagcc ttgagtgcat catgcttgag agcttatacc aggtgaacct
    13981 cggtaaccta cgacgaagct gggtcgccgg tcgtagagca atgagcctcg cccagtttat
    14041 gggcttccac cgaccggata accagacccg ctactacaag gcgctcgacc ccaagacgaa
    14101 ctacgacccc cagatcatgt ggctccgcat catcatcctc gaccgccagc tctgcctctt
    14161 gctcggtcta cccgaaggct gcaccgacca cacgatggcc tcctccgaga cccgcatcgc
    14221 caataactgt cctatgggcc gtctcgagca gctgcactgt gtcgccatgt cccggattct
    14281 cgaccggaac gcatctcagc cgagcggccg ggacctcacc gccacccggg ccatcgacct
    14341 ggagctacag aaagccgccg gcagcctccc aagtaaatgg tggctagccc ccaaactcga
    14401 cagcgcttcc actgacctac aagctatgtt ctgggatacg cgccgccttg tcctgcagat
    14461 ctgccactat aaccttctta accagctgca tctaccgtac atgctccgcc cctcgaccgc
    14521 ggggaataaa tacgagtact cgcggatcac ctgcgtcaat gcctcgcggg aggtgctctc
    14581 acgctacaac tcgctccgta gcttcaatcg catcgcctat agctgccgta cggtcgactt
    14641 cctcgccctg atggccgcca tggccctcct cctcgcccac atggatagct atcgcgacgg
    14701 agcggaaaac ctcctcgcaa accagtatct cagcgatcgg gggatgatcg agcaggtgca
    14761 ggagcatatg agcgagatta accggctgaa ctcggacgag ctgagcgcgc aaagtgcgga
    14821 tcttctgaag tcgttgctgg cgatcgatct ggagaaaggg aagggccggg tgagtgtgcg
    14881 ggaggcgggg agtgagggca tgttgcctca ggatgggatg ggtccggaag aggagagcgt
    14941 cgtgcgggtg catattccgt attttgggat tatccggatt gcgcgcgaga aacagcacgc
    15001 aacgacggcc tccaagccgc cggtcgaccg gtcgcccagc agcaactccg atgcccaact
    15061 tcgcttctcc accctgacac accccagcaa cgccctgccc ctttccccga acaccacctc
    15121 caacccactc tccttcgccg tcgccgacgc agccgctccg catgaattta ccaccccgtt
    15181 cgcgcaccaa cagcaacaac catgtcagcc cacgttctcc aaccccggtt tgtcgctcac
    15241 accatccccg ctaatgcagg gcgggtatcc cgacctcgct gctggcagtg aggactgggc
    15301 gttccagcgg gtggatatgg cgtttttcga gagcatcatg agaaatgttg gaggcgatct
    15361 ttgacccctg ccagcattcg tcgcggtatg tcgcactaac ggccaaacga tcgagaacga
    15421 aacaacaatc cagtatatta aacgaactat gtatgtaata agatgtcctc tgtctgtctg
    15481 cgatttcatt ttgggaacat ggcttttgtt ctccactccc accccagggt gtcgcctata
    15541 gttaggtctg gtttcatcta ccatctgtct acctagtcag atagcagcac agcggagacc
    15601 tagtcaacta ctaagagtgg ttctcctcct tgtccccact gacctttccc tctgcctccg
    15661 atttctcctc tgccgcctcc tccgtcgccg gcttatcctt cttcccatga tcaggcagcc
    15721 ttttaaacgg aatgatcagt gacaaaagaa ccgcaaaggc ggcacacgcc agcgaaaacg
    15781 caaacacatc cttgatgccg accatatacg cggcgatcac ctccgtaaga tcctccccac
    15841 tgaacacgtg ctggagttcg gaggcgccgg tgcctaggac cagggccgga tcgaggtgcc
    15901 cggcaccgga gaggacggtc gcgagcatcc ggttcgcgaa gagggactgc gcgatggcga
    15961 cgaaataggc cccactgagg gtttggcaca ctatcacaac cttgtgttag cgatgcacat
    16021 acatatcccg ttcggtacct aggtaggcac tgcacttgga taggaactgt cataaaggtg
    16081 taacggtgta acggtgtcca ggtgaatact tactaaccat gattccagtc gcgctggaaa
    16141 catcctcctg cttcgagaag ccctgcacgg ccgtcatggg gatctggttg cagataccca
    16201 cgccgaatcc gaacagcacc tcagcgccaa tatacatggc ttggggggag tcgacgtcga
    16261 ggatgtagat cagggccatg ccggcggtca tgatcagggc gccgaggagc tcaaagggct
    16321 gtgtatatcg ggtttttccg atgacgccgc cgctgacgac ggcgccgagg gcgaagaagg
    16381 caaggaacgg gagggtgttg acaccgcttt tcacggcgga ttggccgtgg atggactgga
    16441 agtagatggg caggtaaaac atgacttggt agagggcggc ataggatcta taagacgaag
    16501 gattggcggg ttagccgtga ccggggcatg gatggatgga tggatggcga ggagcgtcgg
    16561 gagggaactt acatgagaca aaatagggcg ttactccatg tcatgcgtag tgtcaagatg
    16621 ctaaagggag tcatggcgcg ttgaccctgg aaccattcgg tcaccaggaa agcaatgctg
    16681 aggacaatcc acatgaccaa ggtcgcgatg accgagccat cattccacgc cttagtctgt
    16741 ccgccccatt gcaaggccaa cgtcaaacag acgagagaga caaggagcag gcagaagccg
    16801 gggagatcca gcgcgaggat gatctcctgc catgtcgcag ggaccttctt gatgtgcttg
    16861 gggatgcgaa ggaataacaa gagcaacacg atgatgggac caccaacggg caagttaatc
    16921 caaaaacacc atctccagga gaccccactc gtgaatccgc cgccaattac cggtcccagg
    16981 atggtcgaca ccataaaaac cgccatccac gtaccgatca gaagcggatg gttcctcggc
    17041 ggggcgacat agttgatgac gataagggtt cctccaagga ccccagaagc gccccagcct
    17101 tgaatggcac gtcctataat aacggacaca ctattcggag ctgctgctgc cacaatactg
    17161 cctaccaaga aaataaagac cgcgctgaga taggtccact tcacgtcgac gtacttaaac
    17221 agcttgcccc agagtggtga agcagccgct gcgaggatga acgtcgcgct tccataccag
    17281 cccacgtcat cgagtcggcg gaactcgttg gtgattccgg gaatggcggt cgcgatgata
    17341 ccaatttcta gcgagacgag gatggtgctc acaaagatcg tgaacatgac gaggatgagt
    17401 cggacgccag tcgcatattc gggcgcaatc tcgtcggggt ctttctgctc ctgagagcca
    17461 ttgctggtcg agccgggctg gcttctgtcc agctcgggtt tgtggttgtt ctcgaggtcg
    17521 gaaccgtctg ccatgattgt ttggatattc tgtggtcaca gcagcccgtc aaagggttga
    17581 gaggttgcaa cttgtagtct ggaatgcaca aagaaacatg ttgaagccat ctcgatgaca
    17641 aaaaaacacg taatgaaggc cgtgatagac acggtcgaac gagcgaagta gacctttcgt
    17701 ccgccgtgtt ttgtatatct tggcagtgga gctcgtgttc gaccgccgga tgatgcatgt
    17761 cttggtagtg gagctcatgt tcgaccgccg ggtcttggcc atgtagcttt cgtccgccgt
    17821 gtcctgttgc agtgctgacc aacgcgagaa gcagctgatt gtccaggcgg ttgagaatta
    17881 ataatggtcc ttttgcactt tcgaccgctg gtggtggacc gtcggatggc ttcgaccgtt
    17941 cgcctcattc ggtagtgtgc tgaccacatg agatctgcat cggcgtaggt cttgagcatg
    18001 ctgactgcat gacattctcc tccgtctata cccctgtcca cgatcatcta aagcttcggt
    18061 aaaacagaat cagggtgatc gtgcaaatgg ccggaccttt cgctcgtttg tttctaggtc
    18121 cctagcgtgt gcggccgaat ccccattcga tagccggtgt taaactgatt ttaacactat
    18181 ccagccgtgt aaacatcgga catctagaac aaggtcgtag ccaggctcgt atcgtcttcc
    18241 gccggggcct gatagcgcca ttctcgtcgg acggacagca gctctcttta aagcctgcac
    18301 gagccgagta cgagtcggag cattcgcacg tgtaatgact ttcttttctt tccgccccct
    18361 tcccagaact aagtctgtaa cgacatcaag atgccttctg cacagcacag cgtgggcgac
    18421 gttcccattg cggtcgtggg cttgtcatgt cgttttcccg gcgacgcgag caccccgtcc
    18481 aaattctggg acatgctgaa gaatggcaaa ggcaaggatt gagccccctc aatcgtgaaa
    18541 ttcgctgctt gggcaatggc agtggactga ctggagtgct acacagatgc ctactccccc
    18601 acatcaacga gatggaactc ggacgcgttc tatcatccag gagacggccg attgaactca
    18661 ctacccacca aggggggaca cttcttgaaa gaagatccgt acgtgttcga tgccgccttc
    18721 ttcaacatca ccgcggcgga agccatcgcc ctcgatccca aacagcggat cgccatggag
    18781 gtgacatacg aagcttttga aaacgcgggc atgtctcttc aacagatttc tggctcccag
    18841 acggcctgtt acatcggctc aggtccgagt gactaccgag gcgccgtgga gcgagatttc
    18901 ttgcacaatc ccaagtatca tcttctcggg accggcgacg agatgatttc caatcgcatc
    18961 tctcatttcc tggatatcca cggccccagt gccacagtgc aaaccgcctg ctcgtccagt
    19021 ctaatggcga ctcacctggc ctgccagagc ttgaggtccg gggaatcaga gatggccatt
    19081 accggtggca tcagtctgat gcttacgcca gacttcacga cacatctgaa caatttgacg
    19141 ttcctcaatc ccgagggctt gtcaaaggcc tttgatgaga gcgcaggcgg atatggtcgc
    19201 ggtgaaggtt gtggaatcat cattttgaaa cggctggccg acgcaatcca agatggtgat
    19261 gacatccgtg ctgtcatccg tggcactggt gcgaactcag atggcttcac acagggtggt
    19321 aagtatgtcc tagtgttatc tgagctggga gtcgctaacc ttcttattta cagtgacaat
    19381 gccgtctttt gaagcacaag ctgcactcat cagacaggtc tactcgtcca acgggttaga
    19441 ctactcaaca caatacgtcg aggcacacgt aagtcaagga ccagtcttcg cgagttacct
    19501 tccctgaccg cagtcttagg gcacggggac caaagccgga gatccaattg aaacaagggc
    19561 catatatagc accattggga agggctcacc gaaaccacgc aaactgtttg taggaagtgt
    19621 caaacctaac gtgagtctcg tggattgtca gcgatatcat gtcgaagacg ctaacttgaa
    19681 cataagatcg gccatctcga atcagcggct ggtgtatcgg gaattatcaa aggcatccta
    19741 tcgatggagc acaatcttat tcccccaaat cttcacttca ctaaagccaa cccggccatt
    19801 ccatttgacg aatggaacat ggctgtacca accaaattga cgccttggcc cgttgctgct
    19861 acaaagcgta tgagcgtcag cggcttcggc atggggggca caaacggtca tgttgtcttg
    19921 gaatcgttcg actccactcg ttccaccaac gggtccggat acagcggagg cttttctaca
    19981 tttgagaaga cccgtaccaa gaaacggctc ttcgttttta gtagccacga ccaggccggc
    20041 ttcaagcgga atgccaatgc attggctgag catttagaca ctgtgggctc tgtagcttcg
    20101 agctctgact tcatggcaaa tttggcccac acactctccg gtgccagatc cagcctctcg
    20161 tggcgggcaa catgtatcgc ggagaataag atcgagctcc gcgattatct gaccaccaag
    20221 ccaggagatg gcgcttcccg ggacgccacc aatgccactc gagccccccg aattggcttc
    20281 gtgttcaccg gacagggtgc ccagtgggct cgaatgggcg tggagatgct cgaccgccca
    20341 gtcttcagag actcggttgc gcaatcgaca cactacctcc aggcgatggg ttgtgtctgg
    20401 gatccagtcg cagagctgaa aaagacgcaa gctgactccc gactgagcca gccagagatc
    20461 agtcagccca tctgctctgt gctccaaatt gcgctcgtcg acgagctgcg gtcgtggggc
    20521 gtgacccctt ccaaagtggt tgggcattcc agcggtgaaa ttgcggccgc atatagcatc
    20581 ggagctctga gccaccgcga cgccattgcg gccgcctact tcaggggtgt ggcgactgtc
    20641 aggcttcggg ctgatgcgcc agacctcaag ggtggcatga tggcggttgg ttgttcacga
    20701 gacgaagcag aggaactgat cgaacagtct aagctcgatg gcaccgctgc cgttgcctgt
    20761 gtgaactcac catccagtgt gacactgtcg ggtgatgttg acacactcga gcaactccga
    20821 gcgatctgtg acgagcataa ggtgtttgtt cggcgactga aagtcgagat ggcgtaccac
    20881 agtaggcata tgaatcgggt ctctggcact tacgctgaat tcatcgccga tcttcaaccc
    20941 atcccccgag agtacaacga gaacgaggac gacgacagca ttcaaaccat gctatccagt
    21001 gtgactgggc aagaggtcgc ccctgagctt ctcgggccat actattgggt ccgcaacttg
    21061 gtttcgccgg tcctcttctc cgacgcagtc aaggagatgg tcgccccaga cgaagctgaa
    21121 ggtgacaata ctgtcgacct gctgatcgaa attggcccac acggcgccct gggcggacct
    21181 gtagagcaaa ttctcggtca ccacggtgtc aaacacatca cctacaagtc gatgctcacg
    21241 cgcggacgca atgcccttga aacgagtctc gagctcgcat ccgagctctt cctcaaaggg
    21301 gtcccaattg acatctccca ggtcaacagt gatctgaacc cccgtcgact gacagacctt
    21361 cccccgtacc aatggaacca ttccaaggtc ttccgccacg agactcgcat tcaacgggag
    21421 cttgtgatgc gccaattccc ctccaagagc attatcggcg cccaagttcc gatgatggat
    21481 gagagccaac atgtctggcg caacttcctc cggttgtccg atgagccctg gatccgtggc
    21541 cacaaggtgg gcagtactgt attattcccc gccgctggtc tcatcggcat ggctcttgag
    21601 gccgcacagc agttggtgga gccaagtaaa acagcacgct cccttcgcct tcgtgatatc
    21661 tcgttctttg ctgccatggc cctttctgag gatgtaccca ccgaggttat catgcacctg
    21721 cggccacacc ttcttgcaac ctcaggttcc acaccagctg cctggtggga gttcaccata
    21781 tcctcatgcg ctggtatcga caacttgcgc gataattgcc gaggattaat caccattgac
    21841 tacgctgaaa cgaccagtga gcagatggct agcgaagatg ccagcttgga ggcgtcgagg
    21901 attgcccatt accaccgcgt ccgcgaggaa tcttcgtaca cttactcgaa agaggacttc
    21961 tacagccaat tcgaaaagat cgcctggaac tatggcgagg ccttccgggg tgtcgagaag
    22021 gtctatcttg gcgacggcca ggccacctat gacgtgaagc tcgtcgatat cggcgagact
    22081 gctagcaaag gacagctcga ccgcccattt ttgatccacg cgggtgccct tgactccatc
    22141 ctccagggct gcctgggaag cacgtaccgg aacgggaggt tcgacatgga caagccagtg
    22201 ttgccgacat tcatcggcca gatggagatc tcactggata ttccgggaga tgctgggtac
    22261 gtcctgccag cggtgtgcga gtcgaagaga catggcttca aggagttgtc gtcaaatata
    22321 tacgcctttg atagtgcagt gtccaaggtc aacttatcgg ttgttgacta ccgagtctcg
    22381 gaattggaga atgactcggg tgagcaggat agtcagcagc ttgaagttga tccggctgag
    22441 atcacctctg aagtgcgctg gaactatgct ctcgaggttc tggagccgga agaaatcaaa
    22501 aaggtggttt tggctgttgc agcggaagat cgggtcgtcg aggtagcctt tatcatctca
    22561 tcattcactt cctaccttca tccgcagact ttactgacaa gctctacagc tgatccgtct
    22621 gtacctccac aataacccgg cagccactgt gatcgagctc gtgccggact atgaggctct
    22681 ggagcgagcg acaatgtcac tgctaccccc cgggaccatt ctcccgagcc atatcaagta
    22741 tgctgtagca gctactggta gcaagtctga aaaccaagtt gatatcgaaa acgtgattgg
    22801 gacacccttc gacctgggcg atttggatga tactttgccc acagatattg cggcggctga
    22861 tttgctggtc atcccgcaat ctgtcaacaa ccataaggac ttgggcgtgc tactgactcg
    22921 tttgacaagt tttggcaagc ctgatgcaag cctggttctt gctgtgaaca gcagtgtgaa
    22981 cgtatctaac tccatgctgg aatctaaggg attccgacgt gtctttgatc tcgagaattc
    23041 agtggcactg tacaaaagcc ggcaatcggg gcatactaat ggacacacca acggccacac
    23101 caacggaaca tctaccagat ccgaattgtt catcatcgag ccactagcaa caagtagtcg
    23161 catcaactct ttctctggtg ctctgcaagt cactctccgc gaacatggct accccgtatt
    23221 tgtgaccaac tggaccgaga tcagtgcccg tccagccgct gacctcgagg gcaacacgtt
    23281 catatcgctt ctggagctcg aacagcccct gctggacgct ctctcggagc cggatttcta
    23341 cagtgtccgc aagcttctgc taaacagtga ccgcctgctc tggatcaccg ccggcgacaa
    23401 cccgtccatg ggcgtggtcg atggcattcg gaggacgatg aggagtgagg tggcgggtct
    23461 caagttccaa gtcttgcatc tgagtagcct ggacacggcg ctgcagtgtg gtccagccct
    23521 tgcaggccgt attatgacga cggatactaa agatgatgag ttccaggagc gagatggcat
    23581 gcttcaggtt gctcggatct tcaacagccc cgaaggaaat gagggcgtgc gtcgctgcct
    23641 ggaagactcc gttcgtgtcg agcggttggg ggagcaagag agagcattga ggcttacgat
    23701 tatgaagcca gggctcatgg acacattgac gttcatcgaa gatgatcgca tgacaggtcc
    23761 gctgggagcg acagagatcg aggtcgatgt caaggcaaca ggtgtcaact tcaaagacat
    23821 catggcggcc atgggccttg tggaagtctc cctcatcggt caagaagcca gtggtatcgt
    23881 cacggccacc ggtagtacag cagcctcacg cttcaagccc ggcgaccggg tgacgcttct
    23941 ctgggagggc atgcatgtca ccaagctgcg catcgatcac cggcttgccg tgcacatacc
    24001 tgactccatg tcgtttgaag aagctgccgc cctacccatg gtccacacca ccgcctacca
    24061 tgcgctcgtc aacgtcgcca aactgcgccc cggtcaatcc gtcctcatcc atgctgctgc
    24121 cggcggtgtc ggtcaagctg cactgcaatt agctacccac ctaggtcttg tggcttatgt
    24181 gactgttggt agcgaggaca agcgccgtct cttgatggag aagtataacg tgccagaagc
    24241 gcatatcttc cactcccgtg atactagctt cgccaaagcc atcaagcgcg tcacgggtgg
    24301 ccggggcgtc gactgcgtgc tcaactcgtt gtcgggcgaa ttgctccgtg tctcatggac
    24361 gtgcctcgcg ccattcggca cgttcgtcga gatcgggctg cgcgatatca cgaataacat
    24421 gcgtctagat atgcgtccgt tcagtcgtag cacaaccttc gcgttcatca acatcgccaa
    24481 tttctttgac ccggagggcc ttgatgcact ggggcagatc ttgtctgacg cctttgccct
    24541 tgtgcataag ggtgttctgg gtacagcgta cccactgaca gtgtaccctg tatctgagct
    24601 tgagacggct ttccgtacta tgcagcaagg caagcatcgc ggaaagctcg ttctctcgtt
    24661 tggagataat gctcaagcac ccgttctctg caaggctaga gatagtctcc gtctcagtcc
    24721 aaagagcacc tatctcttta tcggtggtct cggtggcctt gggcgcagtc tagcgcgcga
    24781 gttcgttgcc tgtggagcac gccacatcgc attcatctct cgctcgggtg attccagtgc
    24841 agaagcgaaa gccaccgtac aagccctcac caccctcggt gccaatgtga aagcctaccg
    24901 tgcagacgta tcagaggaag ccgccttcct ctctgctatg cagcaatgcg ccaccgacct
    24961 ccctcccatt gcaggcgtgg tccaaatggc tatgttgctg cgtgatacgc tcttcgagaa
    25021 aatctcgtac acggattgga cgcagccgat gcgacccaag atccaaggca ccctcaatct
    25081 gcacaattac ttctctgcca cgcgcccgtt ggatttcttc gtcatctgct cctccatctc
    25141 tggtatcttt ggctaccccg gccagacgca atacgccgcc gcgaacacgt tccaagacgc
    25201 cctcgcccgt caccggcgca atcaaggcct caagggcgtg gcggtcgact tgggcatcat
    25261 gcgcgatgtc ggcatccttg ctgagcaagg caccacgggt aaactcgccg actgggaagc
    25321 cattctcggg atccgcgaaa aacccttcca cgcactgatg aagagtgtga tcaacagcga
    25381 gtggaaagga gccgtgcctc cccctgcaca gctgtgtacc ggcctcggga cggccgatat
    25441 catggcccga ttcggattgg agcgaccaga gcatttcagt gatccgcggt ttggcccact
    25501 gaatgtgttg agtatcgaat cctcgtcctc cttgtctacc gatcaagaca ctgcatcatc
    25561 gccctccacg cgtctcgctg ccgcgactac cctcgatgaa gccgtggtta tcatcacgga
    25621 cgcgctggta cacaagatgg cggaaatcct gcagatgccc ttgtccgagg tggatcccgg
    25681 tcggccgatg taccgctatg gtgtggactc gctggtagcg ctggaggtcc ggaattggat
    25741 cactcgagag ctgcaggcga atatggcgct tttggagatt ctggcagcgg agccaatgag
    25801 ggtttttgcg gggaagattg cggagaagag caagttagtt gcaggtcgaa agggttagag
    25861 tgtacctatg atggacataa ggacaagacg ggtcggaact aacccaggta ccggtgaaga
    25921 aactgttgag aatgagttta tttgaactgg tagaaggttt catatgtccg aatgttagat
    25981 ttgaatattc gtagcagtta ccattgcttg aaagaagggc gttgtcggtt ggggaagttg
    26041 gagaagagaa ggtggttgtc caacgaccca caccaaatat atgtcgtgac cagggcggag
    26101 tggaaagttt aagcatgcag acgaggtgag gcatcaaaac catgttgaat tgactatgaa
    26161 aggaatgagg atctcccggc ggtcccagag gagatgttct cgcctatata gaaattgatg
    26221 cccgcgatga tcgtctcctt cggtcgccaa ccgtattgaa gcgagttaga tcgcgaagga
    26281 ggccatctat atcgagtcaa gattactaat gtgtaaggtg acgaacgcca ccctttggga
    26341 tatgaaagtt cacactgtca agatccagct gatgaccacc tcatctgatt gactgttgct
    26401 ttcacgatgt gcgcaccact gcatcctgaa gggagaccta acacagcctc atcatggcca
    26461 aaagagattc ccaatatgct ccccccagac aaaatcgccc agggcgcata cgacctggca
    26521 aaatccatcc tgccggaaag catattcaac cacagcatcc gcgtagctct gctcgcaaag
    26581 tggctcgcag aacgcgagcg gtccgaatgg gcctcgccgg gcaaactgag tctcctcgcc
    26641 gtcgcctgtc tcctgcacga cgtcggatgc gcccaccaat tcgacggcgc tcagcgcttc
    26701 gaggtggaag gcgctgacgc ggcagccagc tacctccgcc agcacgagat tcccaaaagc
    26761 gacatccacg aggtctggca ggcgattgcc ctgcacacga gcccgggcat tgcggagcgc
    26821 atcagttctt gtgcgcgttt agtgcgccag gccgtgctgc ttgattttgg aaagtcgctg
    26881 gatcaagaaa gccaagcctt ccggcagcat atcgaggaga gctttccgcg gattggcatt
    26941 gaaaaggtct tgggggatgt tgtcgtggac caggcactaa gacagcctca gaaggcgccg
    27001 ccggcgtcgt ggccggggat tttgctacgg gcgaaacagg ataatcccga atggactggg
    27061 gttaataaag cgttttgatt gatgagatga cgagtaccaa tgacatgtga catgaggaag
    27121 tgcaattcag agcgttgtgt ccaatggtag ggatgggact gattcgtggt gtacacggac
    27181 cctagtatta gttctcattc tcactatcag catagcccct tcaagccacc agaagcgaac
    27241 caacagaagc cactagtttg agactgtctt ggttacgggc gacaatagta gacaagaata
    27301 gatcgaccat gctggattaa tttctaccga ggcgcccaac cttctgttat aacacccagg
    27361 ctggggccat agggacgcgc cgaatttcag actctgtaca gcatagatag tacccaaagt
    27421 catcaatgat gtgcttctaa tatcgactgt tccaccatcg actccatctt cggctccatg
    27481 tctagaaaac cagtcttaaa ggtagcaaca tggcttcaca tcctcttgcg catcctgctc
    27541 ctactatccg gcatcgccct tctcgccctc gccgtgtaca tggccgtccg atggggcccc
    27601 atcacctccc gcaaaatcta cccaggcgcg ttaactgcgg ttcgtaaaca tgaagcatat
    27661 ctttgaagga gggtatctag ttctgacggc gtataggcga gtctttctat cataaccgac
    27721 atcatcgcca ttatcctgcc gatctccaaa ctggactata tccccactgt tgtcttcttt
    27781 gagattgcca ctttggtcgt cgggctctgg gggctgttca gcctcttgtt cagcgactac
    27841 agctatagca atgctccgca tgacaaccca actgggtggc agcatatgaa tggcattacg
    27901 ctcgcctttg cgattgttct cgtgtgcggt caccagcctt gaagatgtac tgctgagaat
    27961 atgctaactg attacagctg cgagagaacg atttccctca ctgccgtgtg tatatcgtgc
    28021 tgtcgacagg caaggaagcg gaagcgagcg aagcgccagg cgaggacgca ggcaaacgga
    28081 catgtaaacg atgcgatata acactcgtac tggatggatg gtttgtgagc agctgtatct
    28141 tttctgaact tgatagcata tgtgtagccg gtgactctgc ctcattcatt accaaccgca
    28201 acgtattttc caaatccttg agattgggag gagaggcgtt ggcgataaca tgtaggtcgc
    28261 agcgccctac gtaactaggt acctatgtaa ctaggtactt ctctcacccc tcttcatgac
    28321 gcctcattgg ggaatgtaca tgatcatatt tggtgaaagt agcaatgtcc taggaaaacg
    28381 ttccagaagc agagagtatc gcgaaatcca ttgcacacga aagatcacta tgcacactgc
    28441 cagactacat cttccgacgg cgactggagt ctctcggtag atgtcggtac ccactcatcc
    28501 ttggctaaca ggcatcaaat tcctgtagct gcaatccatc ggataaatac agctcatctc
    28561 tgcctaaagc cggccaaatc cccgcaccat ggaacaattg acagaacttc atactacagc
    28621 cagattgtgc ggggcttctt ctgtgcagac atttatactt ggatggggcc ggggaaacat
    28681 gcactcctag tcacagattg cctggtaaaa gagcatagaa agcattcatc atgacccaat
    28741 ccgcagtgta tactttccac gatgcgcttg ccgccatcaa atccggcaaa ccgcttgcac
    28801 aggtcacgca gacactcctc tcccagctca gcaaggacga acgcctggca ctgctcgatg
    28861 gagacgtcga gttctggccc ggtctcggct ctatactccg cgatcgctac aatcgaaccc
    28921 catatgtcca cggcgccgtc ccgcggctgc acatccccgg aatcaggttc acggatggcc
    28981 ctcgtggggt ggttatgcgg aattcgactg cattcccggt gtccatggct cgcggtgcaa
    29041 catgggacct ggagctcgag cgtcgcattg gagacgccat cggtctcgag gccaaagctc
    29101 agggagcaaa ctactttgct ggtgtctgtg tgaatctccc gcgtcaccct gcttggggtc
    29161 gcatccagga gacctacagc gaggatcccc tcctcctggg tgagttcgga ctggcgttga
    29221 cgcagagcgt gcaaaagcat gtgatggcct gtgtcaagca ctatgccctg aactcgatgg
    29281 aaaatgcacg cttccgggtg gatgtgagcg tcgaagagtc ggtcctgcac gaggtctatc
    29341 tggcacactt tcgacgcatc gtcgagggtg gagtggcggc agtcatgtcg gcctataact
    29401 cggtgaatgg agagtgggct gggcagaaca aacacctcct cacggagata cttcgtgagc
    29461 agtgggggtt tgatggcctc atcatgtcag atttcatctt tggacttcgc gatgctgaga
    29521 agtcggtcac gaatggtctg gatatcgaag caccgtttag acagcagcgc gcgatgcatc
    29581 taggagcagc gcttgaacgc ggagacctgt catgggtgga tgttgatcgg tcctgcgaga
    29641 ggatcctgag gaaagaactt gagtttgccg tcaagactga ggatagccag cctggtgctg
    29701 atgtgatctt ctgcgctaag catagagctc tggctcgcga ggcagcggca cggtctatgg
    29761 tgcttctgaa gaacaaccct gttgatggag gtcctgttct acctctacaa gcgacctccc
    29821 tctcccgggt cgctgttgtt ggccgtcttg ctaatgtcgc caacaccgga gacaaaggct
    29881 cttcgcaagt ctttcccccg ggggtagtga cgccactgga aggtattcgt gctgctttgc
    29941 ccggcgtcga ggttttgttt gcggtttctc aaaaagaggc cgagactcta gcctcccagg
    30001 tagacgctgt gatctgcatt gttggctacg atcatgaaga cgaaggggaa tacgtgattc
    30061 ctgctcttct ggagaatcct gctcttcaga acgttcttcc acctccccga aatgacgaag
    30121 agcgcgagac cctggccata ttacaaggac agctcaatcc cggaagtgaa ggtggtgtcg
    30181 aggccggggc aggtggtgat cgtgtctcgc tgcggcttcg tcaagaggac gaagacctca
    30241 tcgccgccgt ggcggctcgc aacccccgta cagtggtgtc gattaccact gcaggtgctg
    30301 tcatcatcga gtcgtggaag aacaaagttc cagcaatctt gatgagctgg tatagtgggt
    30361 gtgaaggagg gcatgccctg gcggacatcc ttctcggaaa gacagatgca agcggacgac
    30421 tgcccttttc catcccagtg gaaggggccc atctgcccta ctttgaccgg gatgcttcaa
    30481 agatctccta tgatcgatgg ttcggacagc atctgctcga caagctgggg gtggaagcgg
    30541 cgttcccctt tggttttggg ctttcctata ccacattcaa cgtgagtgaa gtggctgtcc
    30601 gcagagagga ccctgaacat attcaagtcc agtttgtggt tagaaatact ggagaaagac
    30661 caggacggtt catcgcgcaa gtgtatggct tgcctgggtg cgaggacttt cccactcgcc
    30721 tgttactagg gtttaccccg gtggatctgg aggctggaca ggagatgaat tgccaggtat
    30781 cagcctccct tcggccgttg caacgatgga aagatgggga atacagtctc cggactcggg
    30841 aacttggagt tgaggtggcg agatttgctg gggatgatga agctgcgaga gcacgcacgg
    30901 ttctggcttg atctgaatag agcgtagttc atatagaagc atcacagtct agactactgc
    30961 atgaatgcat tgtcgatgca ttattgtacg aggctgttgg
//
