BGC0000047: 10,11-dihydro-8-deoxy-12,13-deepoxy-12,13-dihydrochalcomycin biosynthetic gene cluster from Streptomyces sp. KCTC 0041BP
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Location: 1 - 75,439 nt. (total: 75,439 nt).
This entry is originally from NCBI GenBank AY118081.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000047
Short description 10,11-dihydro-8-deoxy-12,13-deepoxy-12,13-dihydrochalcomycin biosynthetic gene cluster from Streptomyces sp. KCTC 0041BP
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AY118081.2
via
Compounds
  • 10,11-dihydro-8-deoxy-12,13-deepoxy-12,13-dihydrochalcomycin
Species Streptomyces sp. KCTC 0041BP [taxonomy]
References
Chemical products information
10,11-dihydro-8-deoxy-12,13-deepoxy-12,13-dihydrochalcomycin Evidence:
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C34H58O12
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABB52538.1
  • ger1
 580 - 2118 (-) putative transferase protein
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    • ABB52537.1
    • ger2
    		 2419 - 4473 (-) hypothetical protein
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      • ABB52536.1
      • ger3
      		 4661 - 5656 (-) hypothetical protein
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        • ABB52535.1
        • ger4
        		 5808 - 6812 (-) hypothetical protein
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          • ABB52534.1
          • gerO
          		 6859 - 7863 (-) putative oxidoreductase
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            • ABB52533.1
            • gerB
            		 7964 - 9181 (-) 3,4-dehydratase-like protein
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              • ABB52532.1
              • gerMI
              		 9314 - 10129 (-) sugar-O-methyltransferase
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                • ABB52531.1
                • gerN
                		 10291 - 11748 (-) NDP-4,6-dideoxyhexose-3,4-enoyl reductase
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                  • ABB52530.1
                  • gerR
                  		 11834 - 14305 (-) beta glucosidase
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                    • ABB52529.1
                    • gerPI
                    		 14467 - 15672 (-) cytochrome P-450
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                      • ABB52528.1
                      • gerPII
                      		 15738 - 16961 (-) cytochrome P-450
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                        • ABB52527.1
                        • gerG
                        		 16976 - 17800 (-) type II thioesterase
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                          • ABB52526.1
                          • gerE
                          		 17821 - 18783 (-) dTDP-glucose-4,6-dehydratase
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                            • ABB52525.1
                            • gerD
                            		 18835 - 19722 (-) alpha-D-glucose-1-phosphate thymidylyltransferase
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                              • ABB52524.1
                              • gerF
                              		 20062 - 20652 (-) NDP-hexose-3-epimerase
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                                • ABB52523.1
                                • gerMII
                                		 20718 - 21485 (-) 3-O-methyltransferase
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                                  • ABB52539.1
                                  • gerPIII
                                  		 21746 - 23008 (+) cytochrome P-450
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                                    • ABB52540.1
                                    • gerH
                                    		 23026 - 23247 (+) ferredoxin
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                                      • ABB52541.1
                                      • gerKI
                                      		 23244 - 24224 (+) hexose-4-ketoreductase
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                                        • ABB52542.1
                                        • gerMIII
                                        		 24256 - 25467 (+) O-methyltransferase
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                                          • ABB52543.1
                                          • gerTI
                                          		 25523 - 26779 (+) 6-deoxy-D-allosyltransferase
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                                            • ABB52522.1
                                            • gerA
                                            		 26850 - 27692 (-) 23S rRNA-methyltransferase
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                                              • AAM81584.2
                                              • gerSI
                                              		 27962 - 41125 (+) putative type I polyketide synthase
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                                                • AAM81585.1
                                                • gerSII
                                                		 41222 - 47152 (+) putative type I polyketide synthase
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                                                  • AAM81586.2
                                                  • gerSIII
                                                  		 47282 - 58486 (+) putative type I polyketide synthase
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                                                    • ABB52544.1
                                                    • gerSIV
                                                    		 58537 - 63393 (+) putative type I polyketide synthase
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                                                      • ABB52545.1
                                                      • gerSV
                                                      		 63500 - 67573 (+) putative type I polyketide synthase
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                                                        • ABB52546.1
                                                        • gerY
                                                        		 67655 - 68869 (+) NDP-hexose-3,4-isomerase
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                                                          • ABB52547.1
                                                          • gerTII
                                                          		 68913 - 70190 (+) chalcosyltransferase
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                                                            • ABB52548.1
                                                            • gerKII
                                                            		 70304 - 71050 (+) 3-oxoacyl-(acyl-carrier-protein)-reductase
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                                                              • ABB52549.1
                                                              • ger31
                                                              		 73062 - 74804 (+) putative transcriptional regulator
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                                                                Biosynthesis information
                                                                Annotation changelog

                                                                Entry version: 4

                                                                Date
                                                                Changes
                                                                Submitters
                                                                Reviewers
                                                                2022-10-07
                                                                Update chemical activity to schema version 2.11
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                Entry version: 3

                                                                Date
                                                                Changes
                                                                Submitters
                                                                Reviewers
                                                                2022-09-15
                                                                Updated bioactivity data
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                Entry version: 2

                                                                Date
                                                                Changes
                                                                Submitters
                                                                Reviewers
                                                                2019-10-16
                                                                Migrated from v1.4
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                2019-10-16
                                                                Updated compound(s) information (MIBiG Annotathon)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                Entry version: 1

                                                                Date
                                                                Changes
                                                                Submitters
                                                                Reviewers
                                                                2015-06-12
                                                                Submitted
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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