BGC0000052 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000052 (Streptomyces aizunensis)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	161,719	High	ECO-02301	PKS

BGC0000052 - Region 1 - T1PKS

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Location: 1 - 161,719 nt. (total: 161,719 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 161,720
Label		BGC0000052

Tailoring functions

Oxidoreductases: dehydrogenase

AAX98187.1: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: PPTase acylase glycosyltransferase transferase

AAX98183.1: glycosyltransferase, MGT family

smcogs: SMCOG1062: glycosyltransferase, MGT family

AAX98190.1: malonyl CoA-acyl carrier protein transacylase

smcogs: SMCOG1021: malonyl CoA-acyl carrier protein transacylase

AAX98193.1: malonyl CoA-acyl carrier protein transacylase

smcogs: SMCOG1021: malonyl CoA-acyl carrier protein transacylase

AAX98198.1: glucose-1-phosphate adenylyl/thymidylyltransferase

smcogs: SMCOG1064: glucose-1-phosphate adenylyl/thymidylyltransferase

AAX98203.1: 4'-phosphopantetheinyl transferase

smcogs: SMCOG1060: 4'-phosphopantetheinyl transferase

AAX98206.1: acetyl-CoA carboxylase, carboxyl transferase,

smcogs: SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

Hydrolases: esterase

AAX98200.1: thioesterase

smcogs: SMCOG1004: thioesterase

Lyases: dehydratase

AAX98196.1: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

AAX98199.1: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

Ligases: ligase synthase

AAX98184.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

AAX98185.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

AAX98186.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

AAX98188.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

AAX98189.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

AAX98191.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

AAX98192.1: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

AAX98201.1: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

AAX98208.1: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

AAX98209.1: 8-amino-7-oxononanoate synthase

smcogs: SMCOG1109: 8-amino-7-oxononanoate synthase

AAX98210.1: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000052.5	0.97	PKS	ECO-02301	Streptomyces aizunensis
BGC0002355.2	0.80	PKS, other (other)	tetrafibricin	Streptomyces neyagawaensis
BGC0001244.3	0.76	PKS	(-)-Mellein	Parastagonospora nodorum
BGC0001273.3	0.75	PKS	asperlactone	Aspergillus ochraceus
BGC0001276.3	0.75	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.3	0.75	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0002072.3	0.75	PKS	linearmycin A, linearmycin B, linearmycin C, linearmycin C	Streptomyces sp. Mg1
BGC0002191.2	0.66	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0000041.3	0.65	PKS	oronofacic acid	Pseudomonas syringae
BGC0002357.3	0.64	PKS, other (other)	neomediomycin B	Streptomyces sp. RK95-74

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000052.5	0.99	PKS	ECO-02301	Streptomyces aizunensis
BGC0002355.2	0.80	PKS, other (other)	tetrafibricin	Streptomyces neyagawaensis
BGC0001244.3	0.76	PKS	(-)-Mellein	Parastagonospora nodorum
BGC0001273.3	0.75	PKS	asperlactone	Aspergillus ochraceus
BGC0001276.3	0.75	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.3	0.75	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0002072.3	0.73	PKS	linearmycin A, linearmycin B, linearmycin C, linearmycin C	Streptomyces sp. Mg1
BGC0002191.2	0.66	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0000041.3	0.65	PKS	oronofacic acid	Pseudomonas syringae
BGC0002192.3	0.63	PKS	FR901512	fungal sp. No.14919

Similar known clusters from MIBiG 4.0

Module view

Legend

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 158007:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - ohmal - ccmal - ohmal - ccmal) + (ccmal - ohmal) + (ccmal - ohmal - ohmal - ccmal) + (Me-ohmal) + (ohmal - ccmal - ccmal) + (ccmal - ccmal - ccmal) + (Me-ohmal - Me-ohmal) + (ccmal - redmal - ccmal - ccmal) + (ccmal - ccmal)
Non-colinear ordering:: AAX98184.1 + AAX98185.1 + AAX98186.1 + AAX98187.1 + AAX98188.1 + AAX98189.1 + AAX98190.1 + AAX98191.1 + AAX98192.1

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AAX98184.1: mal - mal - mal - mal - mal

PKS_AT (686..980): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 225.4
inactive: 128.3
Methoxymalonyl-CoA: 61.5
Methylmalonyl-CoA: 52.3
Propionyl-CoA: 28.8
Isobutyryl-CoA: 24.4
Benzoyl-CoA: 21.7
Acetyl-CoA: 16.9
2-Methylbutyryl-CoA: 14.5
Ethylmalonyl-CoA: 12.9
CHC-CoA: 8.6
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (2226..2512): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 229.3
inactive: 114.1
Methoxymalonyl-CoA: 53.3
Methylmalonyl-CoA: 49.4
Propionyl-CoA: 29.7
Acetyl-CoA: 20.4
Benzoyl-CoA: 20.1
Isobutyryl-CoA: 15.4
fatty_acid: 13.0
Ethylmalonyl-CoA: 12.8
2-Methylbutyryl-CoA: 9.3
CHC-CoA: 8.4
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (3751..4039): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 91.7%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 236.0
inactive: 121.7
Methoxymalonyl-CoA: 49.3
Methylmalonyl-CoA: 46.0
Propionyl-CoA: 27.6
Benzoyl-CoA: 18.3
Acetyl-CoA: 16.4
Isobutyryl-CoA: 12.9
CHC-CoA: 10.6
Ethylmalonyl-CoA: 9.9
2-Methylbutyryl-CoA: 9.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (5549..5833): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 234.2
inactive: 112.2
Methoxymalonyl-CoA: 52.4
Methylmalonyl-CoA: 48.9
Propionyl-CoA: 32.2
Acetyl-CoA: 18.8
Benzoyl-CoA: 17.8
Isobutyryl-CoA: 12.2
fatty_acid: 11.7
Ethylmalonyl-CoA: 10.4
CHC-CoA: 9.4
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (7068..7352): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 239.2
inactive: 121.8
Methoxymalonyl-CoA: 54.2
Methylmalonyl-CoA: 52.5
Propionyl-CoA: 33.3
Acetyl-CoA: 20.2
Benzoyl-CoA: 19.5
Isobutyryl-CoA: 14.1
Ethylmalonyl-CoA: 11.8
CHC-CoA: 9.5
2-Methylbutyryl-CoA: 7.9
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

AAX98185.1: mal - mal

PKS_AT (585..869): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 238.6
inactive: 113.2
Methoxymalonyl-CoA: 51.4
Methylmalonyl-CoA: 48.0
Propionyl-CoA: 25.7
Acetyl-CoA: 18.8
Benzoyl-CoA: 18.0
Isobutyryl-CoA: 12.1
fatty_acid: 11.0
CHC-CoA: 9.7
Ethylmalonyl-CoA: 9.5
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (2321..2602): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 232.3
inactive: 112.3
Methoxymalonyl-CoA: 60.7
Methylmalonyl-CoA: 47.8
Propionyl-CoA: 31.0
Acetyl-CoA: 17.3
Benzoyl-CoA: 14.8
Isobutyryl-CoA: 11.9
Ethylmalonyl-CoA: 11.7
fatty_acid: 11.1
CHC-CoA: 11.0
2-Methylbutyryl-CoA: 7.8
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

AAX98186.1: mal - mal - mal - mal

PKS_AT (573..857): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 235.5
inactive: 108.8
Methoxymalonyl-CoA: 52.1
Methylmalonyl-CoA: 47.7
Propionyl-CoA: 26.5
Acetyl-CoA: 20.7
Benzoyl-CoA: 18.2
Isobutyryl-CoA: 12.3
fatty_acid: 10.6
CHC-CoA: 10.3
Ethylmalonyl-CoA: 9.7
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (2380..2664): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Propionyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 232.0
inactive: 113.4
Methoxymalonyl-CoA: 53.5
Methylmalonyl-CoA: 50.3
Propionyl-CoA: 35.7
Benzoyl-CoA: 25.8
Acetyl-CoA: 17.8
Isobutyryl-CoA: 15.3
CHC-CoA: 14.5
Ethylmalonyl-CoA: 13.9
fatty_acid: 13.0
2-Methylbutyryl-CoA: 11.5
trans-1,2-CPDA: 9.6
3-Methylbutyryl-CoA: 0.0

PKS_AT (3892..4176): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 233.4
inactive: 119.8
Methoxymalonyl-CoA: 56.9
Methylmalonyl-CoA: 54.5
Propionyl-CoA: 30.0
Acetyl-CoA: 21.4
Benzoyl-CoA: 21.0
Isobutyryl-CoA: 15.7
fatty_acid: 13.1
Ethylmalonyl-CoA: 12.8
CHC-CoA: 11.0
2-Methylbutyryl-CoA: 9.1
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (5414..5698): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 241.0
inactive: 119.8
Methoxymalonyl-CoA: 56.2
Methylmalonyl-CoA: 52.0
Propionyl-CoA: 29.0
Acetyl-CoA: 19.6
Benzoyl-CoA: 18.8
Isobutyryl-CoA: 13.6
CHC-CoA: 9.8
trans-1,2-CPDA: 8.2
2-Methylbutyryl-CoA: 8.2
Ethylmalonyl-CoA: 6.8
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

AAX98187.1: mmal

PKS_AT (570..869): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 222.6
Ethylmalonyl-CoA: 209.5
Methoxymalonyl-CoA: 181.3
2-Methylbutyryl-CoA: 151.2
trans-1,2-CPDA: 130.1
Malonyl-CoA: 112.1
Propionyl-CoA: 111.6
CHC-CoA: 96.4
Isobutyryl-CoA: 95.4
Benzoyl-CoA: 73.1
3-Methylbutyryl-CoA: 63.0
Acetyl-CoA: 59.0
inactive: 45.5
fatty_acid: 35.6

AAX98188.1: mal - mal - mal

PKS_AT (576..867): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 246.7
inactive: 120.4
Methoxymalonyl-CoA: 59.6
Methylmalonyl-CoA: 50.0
Propionyl-CoA: 40.5
Ethylmalonyl-CoA: 22.0
Benzoyl-CoA: 20.9
Acetyl-CoA: 17.3
Isobutyryl-CoA: 17.0
2-Methylbutyryl-CoA: 16.7
trans-1,2-CPDA: 12.1
CHC-CoA: 12.0
fatty_acid: 9.4
3-Methylbutyryl-CoA: 0.0

PKS_AT (2135..2423): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 91.7%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 234.2
inactive: 121.9
Methoxymalonyl-CoA: 49.2
Methylmalonyl-CoA: 46.6
Propionyl-CoA: 27.1
Benzoyl-CoA: 18.2
Acetyl-CoA: 16.4
Isobutyryl-CoA: 12.8
CHC-CoA: 10.5
2-Methylbutyryl-CoA: 9.2
Ethylmalonyl-CoA: 7.6
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (3899..4187): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 91.7%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 232.7
inactive: 120.0
Methoxymalonyl-CoA: 54.8
Methylmalonyl-CoA: 47.0
Propionyl-CoA: 30.7
Benzoyl-CoA: 18.5
Acetyl-CoA: 15.8
Isobutyryl-CoA: 15.3
Ethylmalonyl-CoA: 11.5
CHC-CoA: 11.1
2-Methylbutyryl-CoA: 8.5
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

AAX98189.1: mal - mal - mal

PKS_AT (578..864): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 235.4
inactive: 115.9
Methoxymalonyl-CoA: 52.7
Methylmalonyl-CoA: 48.0
Propionyl-CoA: 25.2
Acetyl-CoA: 17.8
Benzoyl-CoA: 17.4
Isobutyryl-CoA: 11.8
CHC-CoA: 10.0
Ethylmalonyl-CoA: 8.0
2-Methylbutyryl-CoA: 3.5
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (2356..2640): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 233.3
inactive: 112.5
Methoxymalonyl-CoA: 55.2
Methylmalonyl-CoA: 47.6
Propionyl-CoA: 26.8
fatty_acid: 19.2
Benzoyl-CoA: 18.5
Acetyl-CoA: 17.9
Isobutyryl-CoA: 12.9
Ethylmalonyl-CoA: 10.6
trans-1,2-CPDA: 9.5
CHC-CoA: 8.4
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (4106..4392): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 231.8
inactive: 118.0
Methoxymalonyl-CoA: 58.6
Methylmalonyl-CoA: 46.5
Propionyl-CoA: 25.0
Benzoyl-CoA: 18.3
Acetyl-CoA: 15.8
Isobutyryl-CoA: 13.4
CHC-CoA: 12.2
Ethylmalonyl-CoA: 8.5
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

AAX98190.1: mmal - mmal

PKS_AT (567..866): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 223.1
Ethylmalonyl-CoA: 211.9
Methoxymalonyl-CoA: 181.7
2-Methylbutyryl-CoA: 154.3
trans-1,2-CPDA: 130.5
Malonyl-CoA: 113.4
Propionyl-CoA: 110.7
Isobutyryl-CoA: 99.1
CHC-CoA: 98.7
Benzoyl-CoA: 75.9
3-Methylbutyryl-CoA: 65.7
Acetyl-CoA: 61.7
inactive: 49.0
fatty_acid: 35.5

PKS_AT (2155..2454): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 224.0
Ethylmalonyl-CoA: 207.2
Methoxymalonyl-CoA: 181.4
2-Methylbutyryl-CoA: 152.9
trans-1,2-CPDA: 127.0
Malonyl-CoA: 116.1
Propionyl-CoA: 112.8
CHC-CoA: 100.6
Isobutyryl-CoA: 91.7
Benzoyl-CoA: 71.5
3-Methylbutyryl-CoA: 60.1
Acetyl-CoA: 56.0
inactive: 43.4
fatty_acid: 32.8

AAX98191.1: mal - mal - mal - mal

PKS_AT (596..890): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 228.8
inactive: 125.9
Methoxymalonyl-CoA: 73.0
Methylmalonyl-CoA: 65.9
Propionyl-CoA: 51.3
Ethylmalonyl-CoA: 34.2
Isobutyryl-CoA: 33.9
Benzoyl-CoA: 28.2
2-Methylbutyryl-CoA: 27.2
Acetyl-CoA: 20.7
CHC-CoA: 17.9
fatty_acid: 11.7
trans-1,2-CPDA: 11.6
3-Methylbutyryl-CoA: 0.0

PKS_AT (2370..2669): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 75.0%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 212.6
inactive: 110.6
Methoxymalonyl-CoA: 54.7
Methylmalonyl-CoA: 44.8
Acetyl-CoA: 28.2
Isobutyryl-CoA: 25.4
Propionyl-CoA: 23.9
Benzoyl-CoA: 20.3
Ethylmalonyl-CoA: 17.6
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (4467..4752): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 238.1
inactive: 115.6
Methoxymalonyl-CoA: 56.6
Methylmalonyl-CoA: 53.4
Propionyl-CoA: 29.5
Benzoyl-CoA: 20.5
Acetyl-CoA: 20.4
Isobutyryl-CoA: 15.6
fatty_acid: 14.3
Ethylmalonyl-CoA: 13.6
CHC-CoA: 11.6
trans-1,2-CPDA: 9.8
2-Methylbutyryl-CoA: 9.4
3-Methylbutyryl-CoA: 0.0

PKS_AT (6223..6507): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 236.1
inactive: 122.3
Methoxymalonyl-CoA: 57.0
Methylmalonyl-CoA: 52.9
Propionyl-CoA: 31.6
Benzoyl-CoA: 21.9
Acetyl-CoA: 21.2
Isobutyryl-CoA: 19.0
Ethylmalonyl-CoA: 12.6
CHC-CoA: 12.0
2-Methylbutyryl-CoA: 10.8
fatty_acid: 10.3
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

AAX98192.1: mal - mal

PKS_AT (592..876): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 239.0
inactive: 114.7
Methoxymalonyl-CoA: 53.7
Methylmalonyl-CoA: 50.6
Propionyl-CoA: 32.9
Acetyl-CoA: 18.8
Benzoyl-CoA: 17.8
Isobutyryl-CoA: 12.3
fatty_acid: 11.7
Ethylmalonyl-CoA: 10.3
CHC-CoA: 9.4
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (2339..2623): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 87.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 230.1
inactive: 117.5
Methoxymalonyl-CoA: 54.8
Methylmalonyl-CoA: 51.0
Propionyl-CoA: 27.7
Benzoyl-CoA: 21.9
Acetyl-CoA: 21.2
Isobutyryl-CoA: 17.8
Ethylmalonyl-CoA: 12.6
CHC-CoA: 12.0
fatty_acid: 10.3
2-Methylbutyryl-CoA: 10.3
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

AAX98193.1: pk

PKS_AT (34..307): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

AAX98201.1: X

AMP-binding (18..373): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: QYSDCGSAFK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

AAX98208.1: X

AMP-binding (22..426): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: TVMFISARLK
Nearest Stachelhaus code(s):: 5Me-Pro DVQFISQLLK (35% 8Å match); Trp or Pro DVMFIGAVNK (29% 8Å match)
Stachelhaus code match:: 60% (weak)

AAX98210.1: X

AMP-binding (9..408): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: TFCMYGGPCK
Nearest Stachelhaus code(s):: nLev GFCMYGGCSK (79% 8Å match)
Stachelhaus code match:: 70% (weak)

Link to PARAS substrate predictor