BGC0000057: F9775A biosynthetic gene cluster from Aspergillus nidulans FGSC A4
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Location: 122,623 - 149,174 nt. (total: 26,552 nt).
This entry is originally from NCBI GenBank AACD01000135.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000057
Short description F9775A biosynthetic gene cluster from Aspergillus nidulans FGSC A4
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: partial
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
AACD01000135.1
122623 - 149174
via Knock-out studies, Gene expression correlated with compound production
Compounds
  • F9775A
  • F9775B
  • orsellinic acid
Species Aspergillus nidulans FGSC A4 [taxonomy]
References
Chemical products information
F9775A Evidence:
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C21H16O8
Chemical database entries
PubCHEM
F9775B Evidence:
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C21H16O8
Chemical database entries
PubCHEM
orsellinic acid Evidence:
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C8H8O4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AN7907.2
  • EAA59561.1
 122623 - 123174 (-) hypothetical protein
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    • AN7908.2
    • EAA59562.1
    		 126507 - 127484 (-) hypothetical protein
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      • AN7909.2
      • EAA59563.1
      		 128096 - 134597 (-) polyketide synthase
      • Scaffold biosynthesis
      • Knock-out
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      • AN7910.2
      • EAA59564.1
      		 135422 - 136114 (+) NTF2-like superfamily protein, putative
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        • AN7911.2
        • EAA59565.1
        		 136228 - 137290 (-) aminohydrolase, putative
        • Tailoring
        • Knock-out
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        • AN7912.2
        • EAA59566.1
        		 137660 - 138834 (+) tyrosinase, putative
        • Tailoring
        • Knock-out
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        • AN7913.2
        • EAA59567.1
        		 139355 - 140860 (-) conserved hypothetical protein
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          • AN7914.2
          • EAA59568.1
          		 141414 - 142516 (+) alcohol dehydrogenase, putative
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            • AN7915.2
            • EAA59569.1
            		 142746 - 146016 (-) glucosidase, putative
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              • AN7916.2
              • EAA59570.1
              		 147256 - 149174 (-) hypothetical protein
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                Biosynthesis information

                Biosynthetic modules

                Name
                1
                Type
                pks-modular
                Genes
                AN7909.2
                Substrates
                Integrated Monomers
                Domains
                acyltransferase, ketosynthase, acyltransferase, product_template, thioesterase, carrier (ACP), carrier (ACP), carrier (ACP)
                Annotation changelog

                Entry version: 4

                Date
                Changes
                Submitters
                Reviewers
                2022-10-07
                Update chemical activity to schema version 2.11
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 3

                Date
                Changes
                Submitters
                Reviewers
                2022-09-15
                Removed gene names of 'No gene ID'
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                2022-09-15
                Removed ketoreductase stereochemistry annotation from modules without ketoreductases
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 2

                Date
                Changes
                Submitters
                Reviewers
                2019-10-16
                Migrated from v1.4
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                2015-06-12
                Submitted
                • (ID: J4R6BDENZAM7XVDGVEEHZB2Y)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Detailed domain annotation
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