Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000058.1:
Cluster 1Polyketide174321

BGC0000058, FD-891 biosynthetic gene cluster from Streptomyces graminofaciens. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: FD-891
PubChem ID: 6444177
SMILES string: Copy to clipboard
Molecular formula: C33H54O8
Average molecular mass: 578.787 Da

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:
Type I

Gene cluster description

FD-891 (BGC0000058). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank AB469193. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Kudo F et al. (2010) Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation. Chembiochem 11(11):1574-82. doi: 10.1002/cbic.201000214.