BGC0000066: geldanamycin biosynthetic gene cluster from Streptomyces hygroscopicus
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Location: 1 - 69,644 nt. (total: 69,644 nt).
This entry is originally from NCBI GenBank AY179507.1.

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core biosynthetic genes
additional biosynthetic genes
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resistance
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Gene details
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000066
Short description geldanamycin biosynthetic gene cluster from Streptomyces hygroscopicus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AY179507.1
Compounds
  • geldanamycin
Species Streptomyces hygroscopicus [taxonomy]
References
Chemical products information
geldanamycin
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C30H42N2O8
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAO06909.1
 1 - 684 (-) similar to predicted RhtB family transporters
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  • AAO06910.1
 771 - 1673 (-) putative secreted protein
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  • AAO06911.1
 1945 - 2736 (-) putative hydrolase
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  • AAO06912.1
 2890 - 3774 (+) putative transcriptional regulator
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  • AAO06913.1
 3824 - 4585 (-) putative transcriptional regulator
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  • AAO06914.1
  • gdmL
 4569 - 6065 (+) GdmL
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  • AAO06915.1
  • gdmX
 6107 - 6577 (-) GdmX
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  • AAO06916.1
  • gdmAI
 7208 - 27736 (+) GdmAI
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  • AAO06917.1
  • gdmAII
 27794 - 38101 (+) GdmAII
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  • AAO06918.1
  • gdmAIII
 38128 - 49818 (+) GdmAIII
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  • AAO06919.1
  • gdmF
 49827 - 50600 (+) GdmF
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  • AAO06920.1
  • gdmM
 50597 - 52234 (+) GdmM
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  • AAO06921.1
  • gdmN
 53012 - 55060 (-) GdmN
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  • AAO06922.1
  • gdmH
 55122 - 56234 (-) GdmH
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  • AAO06923.1
  • gdmI
 56231 - 57343 (-) GdmI
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  • AAO06924.1
  • gdmJ
 57340 - 57615 (-) GdmJ
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  • AAO06925.1
  • gdmK
 57612 - 58478 (-) GdmK
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  • AAO06926.1
  • gdmG
 58722 - 59378 (+) GdmG
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  • AAO06927.1
  • gdmRII
 59503 - 62283 (-) GdmRII
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  • AAO06928.1
  • gdmO
 62558 - 63622 (-) GdmO
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  • AAO06929.1
  • gdmP
 63940 - 65133 (-) GdmP
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  • AAO06930.1
  • gdmRI
 65290 - 68178 (-) GdmRI
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  • AAO06931.1
 68931 - 69644 (+) putative hydrolase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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