BGC0000068: geldanamycin biosynthetic gene cluster from Streptomyces hygroscopicus
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Location: 1 - 28,356 nt. (total: 28,356 nt).
This entry is originally from NCBI GenBank DQ914285.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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TTA codons
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Gene details
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000068
Short description geldanamycin biosynthetic gene cluster from Streptomyces hygroscopicus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: DQ914285.1
Compounds
  • geldanamycin
Species Streptomyces hygroscopicus [taxonomy]
References
Chemical products information
geldanamycin
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C29H40N2O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABI93779.1
  • gdmPKS
 2 - 9163 (+) GdmPKS
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  • ABI93780.1
  • gdmF
 9172 - 9945 (+) GdmF
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  • ABI93781.1
  • gdmM
 9942 - 11585 (+) GdmM
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  • ABI93782.1
  • gdmN
 12079 - 14130 (-) GdmN
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  • ABI93783.1
  • gdmH
 14198 - 15310 (-) GdmH
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  • ABI93784.1
  • gdmI
 15307 - 16419 (-) GdmI
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  • ABI93785.1
  • gdmJ
 16416 - 16691 (-) GdmJ
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  • ABI93786.1
  • gdmK
 16688 - 17554 (-) GdmK
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  • ABI93787.1
  • gdmG
 17800 - 18456 (+) gdmG
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  • ABI93788.1
  • gdmRII
 18563 - 21346 (-) GdmRII
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  • ABI93789.1
  • gdmO
 21660 - 22724 (-) GdmO
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  • ABI93790.1
  • gdmP
 23055 - 24257 (-) GdmP
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  • ABI93791.1
  • gdmRI
 24390 - 27296 (-) GdmRI
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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