Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000068.1:
Cluster 1Polyketide128356

BGC0000068, geldanamycin biosynthetic gene cluster from Streptomyces hygroscopicus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: geldanamycin
PubChem ID: 5288382
SMILES string: Copy to clipboard
Molecular formula: C29H40N2O9
Average molecular mass: 560.644 Da

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

geldanamycin (BGC0000068). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank DQ914285. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. He W et al. (2008) The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997. Arch Microbiol 189(5):501-10. doi: 10.1007/s00203-007-0346-2. Epub 2008