BGC0000068: geldanamycin biosynthetic gene cluster from Streptomyces hygroscopicus
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Location: 1 - 28,356 nt. (total: 28,356 nt).
This entry is originally from NCBI GenBank DQ914285.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000068
Short description geldanamycin biosynthetic gene cluster from Streptomyces hygroscopicus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
DQ914285.1
via
Compounds
  • geldanamycin
Species Streptomyces hygroscopicus [taxonomy]
References
Chemical products information
geldanamycin Evidence:
Copy SMILES
C29H40N2O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABI93779.1
  • gdmPKS
 2 - 9163 (+) GdmPKS
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    • ABI93780.1
    • gdmF
    		 9172 - 9945 (+) GdmF
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      • ABI93781.1
      • gdmM
      		 9942 - 11585 (+) GdmM
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        • ABI93782.1
        • gdmN
        		 12079 - 14130 (-) GdmN
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          • ABI93783.1
          • gdmH
          		 14198 - 15310 (-) GdmH
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            • ABI93784.1
            • gdmI
            		 15307 - 16419 (-) GdmI
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              • ABI93785.1
              • gdmJ
              		 16416 - 16691 (-) GdmJ
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                • ABI93786.1
                • gdmK
                		 16688 - 17554 (-) GdmK
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                  • ABI93787.1
                  • gdmG
                  		 17800 - 18456 (+) gdmG
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                    • ABI93788.1
                    • gdmRII
                    		 18563 - 21346 (-) GdmRII
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                      • ABI93789.1
                      • gdmO
                      		 21660 - 22724 (-) GdmO
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                        • ABI93790.1
                        • gdmP
                        		 23055 - 24257 (-) GdmP
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                          • ABI93791.1
                          • gdmRI
                          		 24390 - 27296 (-) GdmRI
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                            Biosynthesis information
                            Annotation changelog

                            Entry version: 4

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2022-10-07
                            Update chemical activity to schema version 2.11
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 3

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2022-09-15
                            Updated bioactivity data
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 2

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2019-10-16
                            Migrated from v1.4
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 1

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2015-06-12
                            Submitted
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            Detailed domain annotation
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