BGC0000074: herbimycin A biosynthetic gene cluster from Streptomyces hygroscopicus
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Location: 1 - 86,941 nt. (total: 86,941 nt).
This entry is originally from NCBI GenBank AY947889.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000074
Short description herbimycin A biosynthetic gene cluster from Streptomyces hygroscopicus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AY947889.1
Compounds
  • herbimycin A
Species Streptomyces hygroscopicus [taxonomy]
References
Chemical products information
herbimycin A
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C30H42N2O9
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAY28209.1
 71 - 2359 (-) unknown
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  • AAY28210.1
 2359 - 2775 (-) unknown
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  • AAY28211.1
 2762 - 3745 (-) unknown
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  • AAY28212.1
 3757 - 5013 (-) unknown
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  • AAY28213.1
 5026 - 6852 (-) unknown
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  • AAY28214.1
 6887 - 8317 (-) putative transmembrane efflux protein
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  • AAY28215.1
 8437 - 9207 (-) unknown
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  • AAY28216.1
 9204 - 10286 (-) FtrD
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  • AAY28217.1
 10286 - 11362 (-) lipoprotein
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  • AAY28218.1
 18360 - 19043 (-) unknown
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  • AAY28219.1
 21063 - 21965 (-) putative secreted protein
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  • AAY28220.1
 22155 - 22946 (-) putative hydrolase
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  • AAY28221.1
 23100 - 23984 (+) putative transcriptional regulator
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  • AAY28222.1
 24036 - 24797 (-) putative transcriptional regulator
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  • AAY28223.1
  • hbmL
 24781 - 26277 (+) HbmL
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  • AAY28224.1
  • hbmX
 26325 - 26795 (-) HbmX
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  • AAY28225.1
  • hbmAI
 27677 - 48139 (+) HbmAI
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  • AAY28226.1
  • hbmAII
 48197 - 58492 (+) HbmAII
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  • AAY28227.1
  • hbmAIII
 58519 - 70125 (+) HbmAIII
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  • AAY28228.1
  • hbmN
 70662 - 72719 (-) HbmN
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  • AAY28229.1
  • hbmH
 72781 - 73893 (-) HbmH
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  • AAY28230.1
  • hbmI
 73890 - 75002 (-) HbmI
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  • AAY28231.1
  • hbmJ
 74999 - 75274 (-) HbmJ
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  • AAY28232.1
  • hbmK
 75271 - 76137 (-) HbmK
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  • AAY28233.1
  • hbmG
 76381 - 77037 (+) HbmG
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  • AAY28234.1
  • hbmRII
 77137 - 79917 (-) HbmRII
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  • AAY28235.1
  • hbmO
 80193 - 81257 (-) HbmO
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  • AAY28236.1
  • hbmFdx
 81334 - 81528 (-) HbmFdx
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  • AAY28237.1
  • hbmP
 81571 - 82764 (-) HbmP
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  • AAY28238.1
  • hbmRI
 82921 - 85764 (-) HbmRI
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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