LOCUS       BGC0000076             36275 bp    DNA     linear   PLN 12-AUG-2008
DEFINITION  Hypomyces subiculosus strain DSM11931 hypothemycin gene cluster,
            partial sequence.
ACCESSION   BGC0000076
VERSION     BGC0000076
KEYWORDS    .
SOURCE      Hypomyces subiculosus
  ORGANISM  Hypomyces subiculosus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae;
            Hypomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 15:36:10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 36275
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..36275
                     /db_xref="taxon:193393"
                     /mol_type="genomic DNA"
                     /organism="Hypomyces subiculosus"
                     /strain="DSM 11931"
     subregion       1..36275
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..36275
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(join(5..462,535..544,606..1180,1241..1267,
                     1343..1853,1909..2054))
                     /gene="Hpm1"
                     /product="cytochrome P450"
     gene            complement(5..2054)
                     /gene="Hpm1"
     misc_feature    5..>36147
                     /note="hypothemycin gene cluster"
     CDS             complement(join(149..462,535..544,606..1180,1241..1267,
                     1343..1853,1909..1980))
                     /codon_start=1
                     /gene="Hpm1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 365.1; E-value:
                     9.1e-111)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450"
                     /protein_id="ACD39751.1"
                     /sec_met_domain="p450 (E-value: 9e-75, bitscore: 241.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAVLPQVDLGHLANRDTAFVIVGAFFAWVFVVNPIYLLYFHPLSK
                     FPGPKFWAVTRWGVSLAIISGKSHDIILDLHKKYGPILRIAPDELAFQSVSAWNDIGGH
                     RKPGQPEMTKEPIFNEAFKDNLLGVTTREDHSRMRRILSRGFSAATFQKQEPLLKGYVD
                     LLLSELRKRCEGGQKLIDIQTWYSFTAFDIIGDLTFGESFGSLDSGGHHPWASLIFETT
                     RFVILANCLKRINRAFLPVLLFITPKGFGRRLKENQQLTDAKIAKRRALGASRPDYMTA
                     MLGNDEKGAKLSDTEITSNCTALILGGAETISSALSGTTYYLTKNPEAMAKVIEEVRSA
                     FSSEDEITLTGTGHLKYLNAVITESLRMFPPFAGASPRQVPRGGATIAGEFIPAGTSVG
                     IWHWSMARCPDFFTHANEFHPERWLDDPRFDNDKKDASQPFAVGPRNCIGMNLTYVELR
                     LILARLFWNFDIKLDKSCDNWVDDMVEYFGWEKIPLMVSLTPRS"
     mRNA            join(2929..3224,3293..3433,3517..3874)
                     /gene="hpm2"
                     /product="glutathione-S-transferase"
     gene            2929..3874
                     /gene="hpm2"
     CDS             join(3004..3224,3293..3433,3517..3793)
                     /codon_start=1
                     /gene="hpm2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1193:glutathione S-transferase (Score: 140.2; E-value:
                     1.1e-42)"
                     /gene_kind="biosynthetic-additional"
                     /product="glutathione-S-transferase"
                     /protein_id="ACD39752.1"
                     /sec_met_domain="GST_N_3 (E-value: 1.9e-20, bitscore: 62.5,
                     seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="GST_C (E-value: 3.5e-13, bitscore: 39.0,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MVIKLYGSAMSTARVLVTLLEKELPYEHILVDISKGDQNKEEYLK
                     LQPFGKVPVLDDNGFIMYESRAICRYLARKYDSGTKLIPDVDDHEAYGRFEQGCSIEYS
                     YFAAAAETLGTELVIKKYKGLGEPDMTRVAQAEADFDKVFFEYDKILAKQKYLTGDEIS
                     LVDLFHLPNASALKAFGYQGTFEKYPNVNRWFSGLQARETWIKATAEAR"
     mRNA            complement(join(4178..5454,5524..8152,8216..8374,
                     8432..8476,8533..10095,10158..10443,10498..10841))
                     /gene="hpm3"
                     /product="non-reducing polyketide synthase"
     gene            complement(4178..10841)
                     /gene="hpm3"
     CDS             complement(join(4283..5454,5524..8152,8216..8374,
                     8432..8476,8533..10095,10158..10443,10498..10793))
                     /NRPS_PKS="Domain: SAT (8-246). E-value: 2.2e-55. Score:
                     179.6. Matches aSDomain: nrpspksdomains_hpm3_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (367-795). E-value:
                     1e-135. Score: 444.8. Matches aSDomain:
                     nrpspksdomains_hpm3_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (888-1183). E-value: 1.4e-83.
                     Score: 272.5. Matches aSDomain:
                     nrpspksdomains_hpm3_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1260-1577). E-value: 6.6e-94. Score:
                     306.6. Matches aSDomain: nrpspksdomains_hpm3_PT.1"
                     /NRPS_PKS="Domain: ACP (1634-1697). E-value: 3e-11. Score:
                     35.4. Matches aSDomain: nrpspksdomains_hpm3_ACP.1"
                     /codon_start=1
                     /gene="hpm3"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 59.9; E-value:
                     3.1e-18)"
                     /gene_kind="biosynthetic"
                     /product="non-reducing polyketide synthase"
                     /protein_id="ACD39753.1"
                     /sec_met_domain="PP-binding (E-value: 2.9e-11, bitscore:
                     33.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.2e-84, bitscore: 272.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.6e-141, bitscore:
                     461.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MVTVPQTILYFGDQTDSWVDSLDQLYRQAATIPWLQTFLDDLVKV
                     FKEESRGMDHALQDSVGEYSTLLDLADRYRHGTDEIGMVRAVLLHAARGGMLLQWVKKE
                     SQLVDLNGSKPEALGISGGLTNLAALAISTDFESLYDAVIEAARIFVRLCRFTSVRSRA
                     MEDRPGVWGWAVLGITPEELSKVLEQFQSSMGIPAIKRAKVGVTGDRWSTVIGPPSVLD
                     LFIHQCPAVRNLPKNELSIHALQHTVTVTEADLDFIVGSAELLSHPIVPDFKVWGMDDP
                     VASYQNWGEMLRAIVTQVLSKPLDITKVIAQLNTHLGPRHVDVRVIGPSSHTPYLASSL
                     KAAGSKAIFQTDKTLEQLQPKKLPPGRIAIVGMAGRGPGCENVDEFWDVIMAKQDRCEE
                     IPKDRFDINEFYCTEHGEGCTTTTKYGCFMNKPGNFDSRFFHVSPREALLMDPGHRQFM
                     MSTYEALETAGYSDGQTRDVDPNRIAAFYGQSNDDWHMVSHYTLGCDAYTLQGAQRAFG
                     AGRIAFHFKWEGPTYSLDSACASTSSAIHLACVSLLSKDVDMAVVGAANVVGYPHSWTS
                     LSKSGVLSDTGNCKTYCDDADGYCRADFVGSVVLKRLEDAVEQNDNILAVVAGSGRNHS
                     GNSSSITTSDAGAQERLFHKIMHSARVSPDEISYVEMHGTGTQIGDPAEMSAVTNVFRK
                     RKANNPLTVGGIKANVGHAEASAGMASLLKCIQMFQKDIMPPQARMPHTLNPKYPSLSE
                     LNIHIPSEPKEFKAIGERPRRILLNNFDAAGGNASLILEDFPSTVKENADPRPSHVIVS
                     SAKTQSSYHANKRNLLKWLRKNKDAKLEDVAYTTTARRMHHPLRFSCSASTTEELISKL
                     EADTADATASRGSPVVFVFTGQGSHYAGMGAELYKTCPAFREEVNLCASISEEHGFPPY
                     VDIITNKDVDITTKDTMQTQLAVVTLEIALAAFWKASGIQPSAVMGHSLGEYVALQVAG
                     VLSLADLLYLVGNRARLLLERCEADTCAMLAVSSSAASIRELIDQRPQSSFEIACKNSP
                     NATVISGSTDEISELQSSFTASRARALSVPYGFHSFQMDPMLEDYIVLAGGVTYSPPKI
                     PVASTLLASIVESSGVFNASYLGQQTRQAVDFVGALGALKEKFADPLWLEIGPSQICSS
                     FVRATLSPSPGKILSTLEANTNPWASISKCLAGAYKDGVAVDWLAVHAPFKGGLKLVKL
                     PAYAWDLKDFWIVYSEANKAARALAPAPSFETQRISTCAQQIVEESSSPSLHVSARAAI
                     SDPGFMALVDGHRMRDVSICPGSVFCEAGLAVSKYALKYSGRKDTVETRLTINNLSLKR
                     PLTKSLVGTDGELLTTVVADKASSDTLQVSWKASSSHASYDLGSCEITICDAQTLQTSW
                     NRSSYFVKARMNELIKNVKSGNGHRMLPSILYTLFASTVDYDPTFKSVKEAFISNEFDE
                     AAAEVVLQKNPAGTQFFASPYWGESVVHLAGFLVNSNPARKTASQTTFMMQSLESVEQT
                     ADLEAGRTYYTYARVLHEEEDTVSCDLFVFDSEKMVMQCSGLSFHEVSNNVLDRLLGKA
                     SPPVKQVSHQKAPVLVPAESKPALKAAVEAAPKAPEPVKTEVKKISSSESELFHTILES
                     IAKETGTQVSDFTDDMELAELGVDSIMGIEIAAGVSSRTGLDVLLPSFVVDYPTIGDLR
                     NEFARSSTSTPPSKTFSEFSIVDATPESTRSSSRAPSEKKEPAPASEKSEELVIVPSAV
                     VEDSSPLPSARITLIQGRSSSGKQPFYLIADGAGSIATYIHLAPFKDKRPVYGIDSPFL
                     RCPSRLTTQVGIEGVAKIIFEALIKCQPEGPFDLGGFSGGAMLSYEVSRQLAAAGRVVS
                     SLLLIDMCSPRPLGVEDTIEVGWKVYETIASQDKLWNASSNTQQHLKAVFACVAAYHPP
                     PMTPAQRPKRTAIIWAKKGMVDRCSRDEKVMKFLADKGIPTESYPGFMEDPKLGAVAWG
                     LPHKSAADLGPNGWDKFLGETLCLSIDSDHLDMPMPGHVHLLQAAMEESFKYFSEAN"
     CDS_motif       complement(4835..4909)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0006"
                     /evalue="5.30E-07"
                     /label="NRPS-te1"
                     /locus_tag="hpm3"
                     /protein_end="1866"
                     /protein_start="1841"
                     /score="22.2"
                     /tool="antismash"
                     /translation="QPEGPFDLGGFSGGAMLSYEVSRQL"
     aSDomain        complement(join(5342..5454,5524..5599))
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_ACP.1"
                     /evalue="3.00E-11"
                     /label="hpm3_ACP.1"
                     /locus_tag="hpm3"
                     /protein_end="1697"
                     /protein_start="1634"
                     /score="35.4"
                     /tool="antismash"
                     /translation="ILESIAKETGTQVSDFTDDMELAELGVDSIMGIEIAAGVSSRTGL
                     DVLLPSFVVDYPTIGDLR"
     aSModule        5342..9576
                     /complete
                     /domains="nrpspksdomains_hpm3_PKS_KS.1"
                     /domains="nrpspksdomains_hpm3_PKS_AT.1"
                     /domains="nrpspksdomains_hpm3_PT.1"
                     /domains="nrpspksdomains_hpm3_ACP.1"
                     /iterative
                     /locus_tags="hpm3"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(5549..5581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0005"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="hpm3"
                     /protein_end="1651"
                     /protein_start="1640"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="KETGTQVSDFT"
     aSDomain        complement(5771..6721)
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_PT.1"
                     /evalue="6.60E-94"
                     /label="hpm3_PT.1"
                     /locus_tag="hpm3"
                     /protein_end="1577"
                     /protein_start="1260"
                     /score="306.6"
                     /tool="antismash"
                     /translation="STCAQQIVEESSSPSLHVSARAAISDPGFMALVDGHRMRDVSICP
                     GSVFCEAGLAVSKYALKYSGRKDTVETRLTINNLSLKRPLTKSLVGTDGELLTTVVADK
                     ASSDTLQVSWKASSSHASYDLGSCEITICDAQTLQTSWNRSSYFVKARMNELIKNVKSG
                     NGHRMLPSILYTLFASTVDYDPTFKSVKEAFISNEFDEAAAEVVLQKNPAGTQFFASPY
                     WGESVVHLAGFLVNSNPARKTASQTTFMMQSLESVEQTADLEAGRTYYTYARVLHEEED
                     TVSCDLFVFDSEKMVMQCSGLSFHEVSNNVLDRLLG"
     aSDomain        complement(6953..7837)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_PKS_AT.1"
                     /evalue="1.40E-83"
                     /label="hpm3_PKS_AT.1"
                     /locus_tag="hpm3"
                     /protein_end="1183"
                     /protein_start="888"
                     /score="272.5"
                     /tool="antismash"
                     /translation="VFTGQGSHYAGMGAELYKTCPAFREEVNLCASISEEHGFPPYVDI
                     ITNKDVDITTKDTMQTQLAVVTLEIALAAFWKASGIQPSAVMGHSLGEYVALQVAGVLS
                     LADLLYLVGNRARLLLERCEADTCAMLAVSSSAASIRELIDQRPQSSFEIACKNSPNAT
                     VISGSTDEISELQSSFTASRARALSVPYGFHSFQMDPMLEDYIVLAGGVTYSPPKIPVA
                     STLLASIVESSGVFNASYLGQQTRQAVDFVGALGALKEKFADPLWLEIGPSQICSSFVR
                     ATLSPSPGKILSTL"
     CDS_motif       complement(7484..7600)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0004"
                     /evalue="7.70E-17"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="hpm3"
                     /protein_end="1006"
                     /protein_start="967"
                     /score="53.4"
                     /tool="antismash"
                     /translation="GIQPSAVMGHSLGEYVALQVAGVLSLADLLYLVGNRARL"
     CDS_motif       complement(7787..7834)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0003"
                     /evalue="1.30E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="hpm3"
                     /protein_end="905"
                     /protein_start="889"
                     /score="17.7"
                     /tool="antismash"
                     /translation="FTGQGSHYAGMGAELY"
     aSDomain        complement(join(8117..8152,8216..8374,8432..8476,
                     8533..9576))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.00E-135"
                     /label="hpm3_PKS_KS.1"
                     /locus_tag="hpm3"
                     /protein_end="795"
                     /protein_start="367"
                     /score="444.8"
                     /tool="antismash"
                     /translation="IAIVGMAGRGPGCENVDEFWDVIMAKQDRCEEIPKDRFDINEFYC
                     TEHGEGCTTTTKYGCFMNKPGNFDSRFFHVSPREALLMDPGHRQFMMSTYEALETAGYS
                     DGQTRDVDPNRIAAFYGQSNDDWHMVSHYTLGCDAYTLQGAQRAFGAGRIAFHFKWEGP
                     TYSLDSACASTSSAIHLACVSLLSKDVDMAVVGAANVVGYPHSWTSLSKSGVLSDTGNC
                     KTYCDDADGYCRADFVGSVVLKRLEDAVEQNDNILAVVAGSGRNHSGNSSSITTSDAGA
                     QERLFHKIMHSARVSPDEISYVEMHGTGTQIGDPAEMSAVTNVFRKRKANNPLTVGGIK
                     ANVGHAEASAGMASLLKCIQMFQKDIMPPQARMPHTLNPKYPSLSELNIHIPSEPKEFK
                     AIGERPRRILLNNFDAAGGNASLILEDFP"
     CDS_motif       complement(8626..8673)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0002"
                     /evalue="2.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="hpm3"
                     /protein_end="684"
                     /protein_start="668"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YVEMHGTGTQIGDPAE"
     CDS_motif       complement(9745..9813)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0001"
                     /evalue="7.40E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="hpm3"
                     /protein_end="311"
                     /protein_start="288"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="GEMLRAIVTQVLSKPLDITKVIA"
     aSDomain        complement(join(9940..10095,10158..10443,10498..10769))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_SAT.1"
                     /evalue="2.20E-55"
                     /label="hpm3_SAT.1"
                     /locus_tag="hpm3"
                     /protein_end="246"
                     /protein_start="8"
                     /score="179.6"
                     /tool="antismash"
                     /translation="LYFGDQTDSWVDSLDQLYRQAATIPWLQTFLDDLVKVFKEESRGM
                     DHALQDSVGEYSTLLDLADRYRHGTDEIGMVRAVLLHAARGGMLLQWVKKESQLVDLNG
                     SKPEALGISGGLTNLAALAISTDFESLYDAVIEAARIFVRLCRFTSVRSRAMEDRPGVW
                     GWAVLGITPEELSKVLEQFQSSMGIPAIKRAKVGVTGDRWSTVIGPPSVLDLFIHQCPA
                     VRNLPKNELSIHALQH"
     mRNA            <11933..>13537
                     /gene="hpm4"
                     /product="hypothetical protein"
     gene            <11933..>13537
                     /gene="hpm4"
     CDS             11933..13537
                     /codon_start=1
                     /gene="hpm4"
                     /product="hypothetical protein"
                     /protein_id="ACD39754.1"
                     /transl_table=1
                     /translation="MSWESPVNYSVGGEDLDLDLGAFLGSLSDFDGQIEPAHSLEDEYS
                     GQSGQGADDDPDSDGPKVLTIMASIDAIHRHLENERKKGNGKANVAIKLKDPTMRKSIT
                     FSIPELQSPTTTASSAGSPSCAPLRLPSPEAFDLGEAIFSHPTAGSSFPEEVTPAAEDD
                     VLSSIASPFATPEGLFFPQDEDVLPSIAPLLKAANLAHATEPSLGLISPRATASESSMM
                     PDEEAMADVVQYRDGTGTTPESLSPGDMEQDEWPHTVSSRQTRSRQAARACQTPSTMST
                     KDKKCIDSSSCSLKQMNSQHQKRNSIETAPSRTIKRPRVESPDLLTLIPNHDEYQRVQE
                     LTAALDPLLAYKMVRNARAILPQSVAEDMAHSADMEVDGPLHYQNNQQSPSSQEEIMQQ
                     FCETVRRIEWVERAAFKSMVEYRVLFVQLYQHYLRLQEIVVTRKGERRVTLAKEQLYRT
                     LYPGVEKMTSSGLTSDEWEKFNRCIRRGKQWNTIASKLGVGILQRMPSSICHSWVEQKL
                     QTKEQLHIWIEIVSLLA"
     mRNA            join(15193..15387,15452..15472,15525..15648,15716..15845,
                     15904..16352,16409..16584,16643..16908)
                     /gene="hpm5"
                     /product="O-methyltransferase"
     gene            15193..16908
                     /gene="hpm5"
     CDS             join(15238..15387,15452..15472,15525..15648,15716..15845,
                     15904..16352,16409..16584,16643..16789)
                     /codon_start=1
                     /gene="hpm5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 163.7; E-value:
                     1.1e-49)"
                     /gene_kind="biosynthetic-additional"
                     /product="O-methyltransferase"
                     /protein_id="ACD39755.1"
                     /transl_table=1
                     /translation="MSASNGEIVQRIESLLASAKKLQGDDQYGRFGLLKEIDLLYQDVE
                     PPINTFFKQWTSLTFFSCIDIAIKLGLFEHMKGRESITAKELGALVNVDDDVIARVMRV
                     LVASRFVASKGEDAYAHTHKSLVYVKGEHTAVDSFNLISLLAVSYITIPEYLKTRSADE
                     LVDIRKTPYACAYGMEGKTFYEVLSTNPDHLDTFNRSMSEPGPEWGMFPFESLRENVLA
                     EPERPFVVDIGGGKGQALLRIQEETGKVFGTSSQLILQERPDVLEQINQDDIAGITKMP
                     YDFHTKQPVKDAHVYFFSQIIHNYPDHVCQDILKQAAGAMGPSSRLLIVEAVLPAQTDV
                     GGDMGAYLIDFVGLAMGGKERTEKEFATLLGTVGLELVKVWHGKARHHAIVEARLKRA"
     mRNA            join(<17948..18449,18519..>19711)
                     /gene="hpm6"
                     /product="major facilitator superfamily transporter"
     gene            <17948..>19711
                     /gene="hpm6"
     CDS             join(17948..18449,18519..19711)
                     /codon_start=1
                     /gene="hpm6"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 344.2; E-value:
                     1.5e-104)"
                     /gene_kind="transport"
                     /product="major facilitator superfamily transporter"
                     /protein_id="ACD39756.1"
                     /transl_table=1
                     /translation="MEKHAEPEKSLGDKEFQEKELHEKPAPAASEDISGDSSVNKEDGP
                     DPINDNYLSGLRLAVVMFALCISNFLVALDTTILATAVPKISSDFNSLQDVGWYTSSYL
                     LTNCAFQLFYGKLYTRFKVKIVFTVAMIIFEIGSLLCGVAPNSPVFIFGRAIAGLGSAG
                     AFSGALIIVIHSVQAEKRAQYSGMIVGMYGLASVAAPLIGGAFTDHVTWRWCFYINLPC
                     GGVAIAGLLFFFHSPPQAAVKETAAGLWAKIAKFDPFGTFFFLCSMICLLLALQMGGST
                     YPFTDARIIVLLVLFGLLLVAFIVVQFFDKNATIPPRVMKNRSVAFGMIYMFCVGAQFL
                     VLVTFMPIWFQGVRAMSATDSGIRSLPILLSNTFCVVLAGALVSMTGYYIPFMWASVVL
                     TSIGAGLLTTLTVDASTGKWVGYQIIAGIGGGLGYQQGISVAQTVLKGSDMTIGTAVMV
                     FVQLLGGTILVSAANNILVTRLVENLERLAPHINPEIILRAGASGIKTAVSEADYPFVI
                     EAYNIALTKTFQIALIVSCLGAIGAAGVEWKRGSKKGDSDEPAIMAV"
     mRNA            join(22018..22424,22482..23245,23337..24085)
                     /gene="hpm7"
                     /product="flavin-dependent monooxygenase"
     gene            22018..24085
                     /gene="hpm7"
     CDS             join(22079..22424,22482..23245,23337..24035)
                     /codon_start=1
                     /gene="hpm7"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 413.1; E-value: 3.1e-125)"
                     /gene_kind="other"
                     /product="flavin-dependent monooxygenase"
                     /protein_id="ACD39757.1"
                     /transl_table=1
                     /translation="MTRAILPDVSPDSIDPQFLEEKYDQERLKRINAAGYAKYSEVGDG
                     ELERFKVTHRLEDVASSREPVSVDTDVVIIGAGYAGILTAVRLVQNGILNFRIVEKGNG
                     FGGTWYWNQYPGAQCDVESYIYMPLLEETGYVPTERYARGPEILKHINLIAKKWELAPK
                     THFQSEVSAADWTADRWTVKTRQGDEFRSRYLVTAIGPFHRPKLPGVPGINSFKGNTFH
                     SSGWDYEASGGSATEKLTKFSDKTIGIIGTGATAVQMLPFVANSAKEVLVFQRTPAPVN
                     VRNNGPTPPDFAKFLEPGWQLRRMDNFNKIYTGEPIDTSIVSEEWLSATLQVLFGTESD
                     KPSDPAELEQLLARTDFQVMERIRRRVDETIKDPVTREQLKPWYATICKRPCFHDEYLE
                     CFNRPNVRLVDTDGKGVDRITEDSVVVDGKEHHVDALVFCTGFEYLSGVDRHGGFTVTG
                     KDGVTLTERWTPGPSTYHGLYVHGFPNFFCLQTAQAGTNPNFMYTATTGSTQIGHVIAE
                     CLKDGVREVQPTKQAEDDWVKMILEGGRGMMHLMRNCTPGYMNNDGNLDEKTARRMFYP
                     GGPTAWRKLLEAWREKGDFEGLQRTY"
     mRNA            join(25642..25814,25909..26741,26802..26912,26969..27555,
                     27609..28676,28737..31037,31101..31436,31509..33363)
                     /gene="hpm8"
                     /product="reducing polyketide synthase"
     gene            25642..33363
                     /gene="hpm8"
     CDS             join(25697..25814,25909..26741,26802..26912,26969..27555,
                     27609..28676,28737..31037,31101..31436,31509..33204)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (11-436). E-value:
                     1.7e-172. Score: 565.9. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (551-862). E-value: 4.6e-96.
                     Score: 313.5. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (931-1120). E-value: 2.2e-22.
                     Score: 72.0. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1640-1953). E-value: 1.6e-118.
                     Score: 387.2. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1976-2156). E-value: 2.3e-51.
                     Score: 166.1. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2265-2339). E-value: 4e-12.
                     Score: 38.2. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_PP.1"
                     /codon_start=1
                     /gene="hpm8"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 252.3; E-value:
                     1.5e-76)"
                     /gene_kind="biosynthetic"
                     /product="reducing polyketide synthase"
                     /protein_id="ACD39758.1"
                     /sec_met_domain="PP-binding (E-value: 7.2e-08, bitscore:
                     22.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 2.9e-173, bitscore:
                     565.9, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7.6e-97, bitscore: 313.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.1e-46, bitscore:
                     148.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 1.8e-08, bitscore: 23.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.8e-19, bitscore:
                     58.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPSTSNPSHVPVAIIGLACRFPGEATSPSKFWDLLKNGRDAYSPN
                     TDRYNADAFYHPKASNRQNVLATKGGHFLKQDPYVFDAAFFNITAAEAISFDPKQRIAM
                     EVVYEALENAGKTLPKVAGTQTACYIGSSMSDYRDAVVRDFGNSPKYHILGTCEEMISN
                     RVSHFLDIHGPSATIHTACSSSLVATHLACQSLQSGESEMAIAGGVGMIITPDGNMHLN
                     NLGFLNPEGHSRSFDENAGGYGRGEGCGILILKRLDRALEDGDSIRAVIRASGVNSDGW
                     TQGVTMPSSQAQSALIKYVYESHGLDYGATQYVEAHGTGTKAGDPAEIGALHRTIGQGA
                     SKSRRLWIGSVKPNIGHLEAAAGVAGIIKGVLSMEHGMIPPNIYFSKPNPAIPLDEWNM
                     AVPTKLTPWPASQTGRRMSVSGFGMGGTNGHVVLEAYKPQGKLTNGHTNGITNGIHKTR
                     HSGKRLFVLSAQDQAGFKRLGNALVEHLDALGPAAATPEFLANLSHTLAVGRSGLAWRS
                     SIIAESAPDLREKLATDPGEGAARSSGSEPRIGFVFTGQGAQWARMGVELLERPVFKAS
                     VIKSAETLKELGCEWDPIVELSKPQAESRLGVPEISQPICTVLQVALVDELKHWGVSPS
                     KVVGHSSGEIGAAYSIGALSHRDAVAAAYFRGKSSNGAKKLGGGMMAVGCSREDADKLL
                     SETKLKGGVATVACVNSPSSVTISGDATALEELRVILEEKSVFARRLKVDVAYHSAHMN
                     AVFAEYSAAIAHIEPAQAVEGGPIMVSSVTGSEVDSELLGPYYWTRNLISPVLFADAVK
                     ELVTPADGDGQNTVDLLIEIGPHSALGGPVEQILSHNGIKNVAYRSALTRGENAVDCSL
                     KLAGELFLLGVPFELQKANGDSGSRMLTNLPPYPWNHSKSFRADSRLHREHLEQKFPTR
                     SLIGAPVPMMAESEYTWRNFIRLADEPWLRGHTVGTTVLFPGAGIVSIILEAAQQLVDT
                     GKTVRGFRMRDVNLFAAMALPEDLATEVIIHIRPHLISTVGSTAPGGWWEWTVSSCVGT
                     DQLRDNARGLVAIDYEESRSEQINAEDKALVASQVADYHKILSECPEHYAHDKFYQHMT
                     KASWSYGELFQGVENVRPGYGKTIFDIRVIDIGETFSKGQLERPFLINAATLDAVFQSW
                     LGSTYNNGAFEFDKPFVPTSIGELEISVNIPGDGDYLMPGHCRSERYGFNELSADIAIF
                     DKDLKNVFLSVKDFRTSELDMDSGKGDGDAAHVDPADINSEVKWNYALGLLKSEEITEL
                     VTKVASNDKLAELLRLTLHNNPAATVIELVSDESKISGASSAKLSKGLILPSQIRYVVV
                     NPEAADADSFFKFFSLGEDGAPVAAERGPAELLIASSEVTDAAVLERLITLAKPDASIL
                     VAVNNKTTAAALSAKAFRVVTSIQDSKSIALYTSKKAPAADTSKLEAIILKPTTAQPAA
                     QNFASILQKALELQGYSVVSQPWGTDIDVNDAKGKTYISLLELEQPLLDNLSKSDFENL
                     RAVVLNCERLLWVTAGDNPSFGMVDGFARCIMSEIASTKFQVLHLSAATGLKYGSSLAT
                     RILQSDSTDNEYREVDGALQVARIFKSYNENESLRHHLEDTTSVVTLADQEDALRLTIG
                     KPGLLDTLKFVPDERMLPPLQDHEVEIQVKATGLNFRDIMACMGLIPVRSLGQEASGIV
                     LRTGAKATNFKPGDRVCTMNVGTHATKIRADYRVMTKIPDSMTFEEAASVAVVHTTAYY
                     AFITIAKLRKGQSVLIHAAAGGVGQAAIQLAKHLGLITYVTVGTEDKRQLIREQYGIPD
                     EHIFNSRDASFVKGVQRVTNGRGVDCVLNSLSGELLRASWGCLATFGHFIEIGLRDITN
                     NMRLDMRPFRKSTSFTFINTHTLFEEDPAALGDILNESFKLMFAGALTAPSPLNAYPIG
                     QVEEAFRTMQQGKHRGKMVLSFSDDAKAPVLRKAKDSLKLDPDATYLFVGGLGGLGRSL
                     AKEFVASGARNIAFLSRSGDTTAQAKAIVDELAGQGIQVKAYRGDIASEASFLQAMEQC
                     SQDLPPVKGVIQMAMVLRDIVFEKMSYDEWTVPVGPKVQGSWNLHKYFSHERPLDFMVI
                     CSSSSGIYGYPSQAQYAAGNTYQDALAHYRRSQGLNAISVNLGIMRDVGVLAETGTTGN
                     IKLWEEVLGIREPAFHALMKSLINHQQRGSGDYPAQVCTGLGTADIMATHGLARPEYFN
                     DPRFGPLAVTTVATDASADGQGSAVSLASRLSKVSTKDEAAEIITDALVNKTADILQMP
                     PSEVDPGRPLYRYGVDSLVALEVRNWITREMKANMALLEILAAVPIESFAVKIAEKSKL
                     VTV"
     aSDomain        join(25730..25814,25909..26741,26802..26912,26969..27214)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.70E-172"
                     /label="hpm8_PKS_KS.1"
                     /locus_tag="hpm8"
                     /protein_end="436"
                     /protein_start="11"
                     /score="565.9"
                     /tool="antismash"
                     /translation="VAIIGLACRFPGEATSPSKFWDLLKNGRDAYSPNTDRYNADAFYH
                     PKASNRQNVLATKGGHFLKQDPYVFDAAFFNITAAEAISFDPKQRIAMEVVYEALENAG
                     KTLPKVAGTQTACYIGSSMSDYRDAVVRDFGNSPKYHILGTCEEMISNRVSHFLDIHGP
                     SATIHTACSSSLVATHLACQSLQSGESEMAIAGGVGMIITPDGNMHLNNLGFLNPEGHS
                     RSFDENAGGYGRGEGCGILILKRLDRALEDGDSIRAVIRASGVNSDGWTQGVTMPSSQA
                     QSALIKYVYESHGLDYGATQYVEAHGTGTKAGDPAEIGALHRTIGQGASKSRRLWIGSV
                     KPNIGHLEAAAGVAGIIKGVLSMEHGMIPPNIYFSKPNPAIPLDEWNMAVPTKLTPWPA
                     SQTGRRMSVSGFGMGGTNGHVVLEAY"
     aSModule        25730..33171
                     /complete
                     /domains="nrpspksdomains_hpm8_PKS_KS.1"
                     /domains="nrpspksdomains_hpm8_PKS_AT.1"
                     /domains="nrpspksdomains_hpm8_PKS_DH.1"
                     /domains="nrpspksdomains_hpm8_PKS_ER.1"
                     /domains="nrpspksdomains_hpm8_PKS_KR.1"
                     /domains="nrpspksdomains_hpm8_PKS_PP.1"
                     /iterative
                     /locus_tags="hpm8"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       26145..26165
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0001"
                     /evalue="1.10E+01"
                     /label="PKSI-KR_m3"
                     /locus_tag="hpm8"
                     /protein_end="125"
                     /protein_start="118"
                     /score="0.5"
                     /tool="antismash"
                     /translation="PKVAGTQ"
     CDS_motif       26307..26354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0002"
                     /evalue="9.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="hpm8"
                     /protein_end="188"
                     /protein_start="172"
                     /score="17.7"
                     /tool="antismash"
                     /translation="GPSATIHTACSSSLVA"
     CDS_motif       26496..26534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0003"
                     /evalue="1.80E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="hpm8"
                     /protein_end="248"
                     /protein_start="235"
                     /score="8.6"
                     /tool="antismash"
                     /translation="FDENAGGYGRGEG"
     CDS_motif       join(26727..26741,26802..26834)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0004"
                     /evalue="3.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="hpm8"
                     /protein_end="328"
                     /protein_start="312"
                     /score="12.9"
                     /tool="antismash"
                     /translation="YVEAHGTGTKAGDPAE"
     CDS_motif       join(26895..26912,26969..26995)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0005"
                     /evalue="8.80E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="hpm8"
                     /protein_end="363"
                     /protein_start="348"
                     /score="11.8"
                     /tool="antismash"
                     /translation="GSVKPNIGHLEAAAG"
     CDS_motif       27610..27663
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0006"
                     /evalue="3.30E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="hpm8"
                     /protein_end="568"
                     /protein_start="550"
                     /score="19.4"
                     /tool="antismash"
                     /translation="FVFTGQGAQWARMGVELL"
     aSDomain        27613..28545
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_AT.1"
                     /evalue="4.60E-96"
                     /label="hpm8_PKS_AT.1"
                     /locus_tag="hpm8"
                     /protein_end="862"
                     /protein_start="551"
                     /score="313.5"
                     /tool="antismash"
                     /translation="VFTGQGAQWARMGVELLERPVFKASVIKSAETLKELGCEWDPIVE
                     LSKPQAESRLGVPEISQPICTVLQVALVDELKHWGVSPSKVVGHSSGEIGAAYSIGALS
                     HRDAVAAAYFRGKSSNGAKKLGGGMMAVGCSREDADKLLSETKLKGGVATVACVNSPSS
                     VTISGDATALEELRVILEEKSVFARRLKVDVAYHSAHMNAVFAEYSAAIAHIEPAQAVE
                     GGPIMVSSVTGSEVDSELLGPYYWTRNLISPVLFADAVKELVTPADGDGQNTVDLLIEI
                     GPHSALGGPVEQILSHNGIKNVAYRSALTR"
     CDS_motif       27850..27942
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0007"
                     /evalue="4.10E-09"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="hpm8"
                     /protein_end="661"
                     /protein_start="630"
                     /score="28.9"
                     /tool="antismash"
                     /translation="GVSPSKVVGHSSGEIGAAYSIGALSHRDAVA"
     aSDomain        28813..29379
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_DH.1"
                     /evalue="2.20E-22"
                     /label="hpm8_PKS_DH.1"
                     /locus_tag="hpm8"
                     /protein_end="1120"
                     /protein_start="931"
                     /score="72.0"
                     /tool="antismash"
                     /translation="LIGAPVPMMAESEYTWRNFIRLADEPWLRGHTVGTTVLFPGAGIV
                     SIILEAAQQLVDTGKTVRGFRMRDVNLFAAMALPEDLATEVIIHIRPHLISTVGSTAPG
                     GWWEWTVSSCVGTDQLRDNARGLVAIDYEESRSEQINAEDKALVASQVADYHKILSECP
                     EHYAHDKFYQHMTKASWSYGELFQGV"
     CDS_motif       28891..28968
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0008"
                     /evalue="1.00E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="hpm8"
                     /protein_end="983"
                     /protein_start="957"
                     /score="27.7"
                     /tool="antismash"
                     /translation="WLRGHTVGTTVLFPGAGIVSIILEAA"
     aSDomain        join(30940..31037,31101..31436,31509..32013)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_ER.1"
                     /evalue="1.60E-118"
                     /label="hpm8_PKS_ER.1"
                     /locus_tag="hpm8"
                     /protein_end="1953"
                     /protein_start="1640"
                     /score="387.2"
                     /tool="antismash"
                     /translation="GLLDTLKFVPDERMLPPLQDHEVEIQVKATGLNFRDIMACMGLIP
                     VRSLGQEASGIVLRTGAKATNFKPGDRVCTMNVGTHATKIRADYRVMTKIPDSMTFEEA
                     ASVAVVHTTAYYAFITIAKLRKGQSVLIHAAAGGVGQAAIQLAKHLGLITYVTVGTEDK
                     RQLIREQYGIPDEHIFNSRDASFVKGVQRVTNGRGVDCVLNSLSGELLRASWGCLATFG
                     HFIEIGLRDITNNMRLDMRPFRKSTSFTFINTHTLFEEDPAALGDILNESFKLMFAGAL
                     TAPSPLNAYPIGQVEEAFRTMQQGKHRGKMVL"
     CDS_motif       join(31030..31037,31101..31128)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0009"
                     /evalue="6.90E-04"
                     /label="PKSI-ER_m1"
                     /locus_tag="hpm8"
                     /protein_end="1682"
                     /protein_start="1670"
                     /score="12.6"
                     /tool="antismash"
                     /translation="GLNFRDIMACMG"
     CDS_motif       31312..31356
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0010"
                     /evalue="1.30E-01"
                     /label="PKSI-ER_m4"
                     /locus_tag="hpm8"
                     /protein_end="1758"
                     /protein_start="1743"
                     /score="6.2"
                     /tool="antismash"
                     /translation="AASVAVVHTTAYYAF"
     CDS_motif       join(31381..31436,31509..31515)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0011"
                     /evalue="2.00E-10"
                     /label="PKSI-ER_m5"
                     /locus_tag="hpm8"
                     /protein_end="1787"
                     /protein_start="1766"
                     /score="32.8"
                     /tool="antismash"
                     /translation="GQSVLIHAAAGGVGQAAIQLA"
     CDS_motif       31654..31692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0012"
                     /evalue="1.10E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="hpm8"
                     /protein_end="1846"
                     /protein_start="1833"
                     /score="14.7"
                     /tool="antismash"
                     /translation="TNGRGVDCVLNSL"
     CDS_motif       31966..32013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0013"
                     /evalue="4.20E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="hpm8"
                     /protein_end="1953"
                     /protein_start="1937"
                     /score="19.6"
                     /tool="antismash"
                     /translation="AFRTMQQGKHRGKMVL"
     aSDomain        32083..32622
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_KR.1"
                     /evalue="2.30E-51"
                     /label="hpm8_PKS_KR.1"
                     /locus_tag="hpm8"
                     /protein_end="2156"
                     /protein_start="1976"
                     /score="166.1"
                     /tool="antismash"
                     /translation="ATYLFVGGLGGLGRSLAKEFVASGARNIAFLSRSGDTTAQAKAIV
                     DELAGQGIQVKAYRGDIASEASFLQAMEQCSQDLPPVKGVIQMAMVLRDIVFEKMSYDE
                     WTVPVGPKVQGSWNLHKYFSHERPLDFMVICSSSSGIYGYPSQAQYAAGNTYQDALAHY
                     RRSQGLNAISVNLGIMR"
     CDS_motif       32086..32184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0014"
                     /evalue="4.20E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="hpm8"
                     /protein_end="2010"
                     /protein_start="1977"
                     /score="48.3"
                     /tool="antismash"
                     /translation="TYLFVGGLGGLGRSLAKEFVASGARNIAFLSRS"
     CDS_motif       32413..32442
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0015"
                     /evalue="9.40E-04"
                     /label="PKSI-KR_m3"
                     /locus_tag="hpm8"
                     /protein_end="2096"
                     /protein_start="2086"
                     /score="12.5"
                     /tool="antismash"
                     /translation="PKVQGSWNLH"
     CDS_motif       32467..32577
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0016"
                     /evalue="2.90E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="hpm8"
                     /protein_end="2141"
                     /protein_start="2104"
                     /score="58.4"
                     /tool="antismash"
                     /translation="LDFMVICSSSSGIYGYPSQAQYAAGNTYQDALAHYRR"
     aSDomain        32950..33171
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_PP.1"
                     /evalue="4.00E-12"
                     /label="hpm8_PKS_PP.1"
                     /locus_tag="hpm8"
                     /protein_end="2339"
                     /protein_start="2265"
                     /score="38.2"
                     /tool="antismash"
                     /translation="DEAAEIITDALVNKTADILQMPPSEVDPGRPLYRYGVDSLVALEV
                     RNWITREMKANMALLEILAAVPIESFAVK"
     mRNA            join(<34182..34370,34450..>36147)
                     /gene="hpm9"
                     /product="alcohol oxidase"
     gene            <34182..>36147
                     /gene="hpm9"
     CDS             join(34182..34370,34450..36147)
                     /codon_start=1
                     /gene="hpm9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 358;
                     E-value: 1.9e-108)"
                     /gene_kind="biosynthetic-additional"
                     /product="alcohol oxidase"
                     /protein_id="ACD39759.1"
                     /transl_table=1
                     /translation="MFCIIRAQLLLLLHLLVLALLLVGTVCNAHPQHGHPSELEPLALK
                     RGGSPRDDGNTLAPRCRCIPGEACWPSTQIWDSFNRTIGGSLIKTAPLAESCYPGPKKN
                     TRKCAVVSRKWTDQDFQTDSPVGRTYPYNITCAPVNYFAGQRPTTCSLGQLPVYAIDAR
                     TRQSVAQGLRFAKDNNLRVTVVSTGHDLLGRADGYGSLEIWLRHHRNEIRFERQYMATD
                     GCRESGWTGSAIDIDGAYQWRDVHIKARANNVIVVGGGSVSPGAIGGWPSGGGHGPASR
                     NYGLGADQILEAEVMLADGSVVLANHCQHTDLFRALRGGGPGFGVVLKTKIKAYPNVAS
                     VSVHHLTITPIRQTPNNSDLLDAVAVLMQAYPKLSDDGYAGYAFWLRNCKSFFIGSAKS
                     GYRHGIWMIGKTTEEAEHSFAPVREALDKFKSKLTISESYMTYNDYWSFYTSESGLYES
                     VGTTSVLTSRLIDRPAVEDYNRVREAVEVIGGKPEDYATNVMMLVSNGQVFADAADKSS
                     GLNPAWRVSPYVVISSRGIPMVVDQASRKEVADDITYVKGAALQKLAPNTGGYMNEGDR
                     NDPNYIKNFFGTIYPTHLATKKKYDPWGLFYCPTCVGAELFEETSRGELCRR"
ORIGIN
        1 tctcttggaa atcttggatg gtatggtatt gaagactaac tcggcagtgc catgtttata
       61 ggttggttgt agtctgtgag ttgggactca ctgtcactgc tactcaggac attagatggc
      121 agtcgagact acctactttt acatcatttt aggaccttgg agtcaaggac accattaggg
      181 ggattttctc ccagccaaag tattccacca tgtcatccac ccaattatcg cagctcttgt
      241 caagcttaat atcaaagttc cagaagagtc tcgccaagat cagtcgcagc tcgacgtagg
      301 tcagattcat gccgatgcag ttacgggggc ccaccgcgaa gggttgtgaa gcatccttct
      361 tgtcattatc gaaacgggga tcatcgagcc agcgctcggg gtggaattcg ttggcatgcg
      421 tgaagaagtc cgggcagcga gccatgctcc aatgccaaat gcctgtgtca ccagttagct
      481 atttgtttgg ccctgaagat aaagatggat ggtccacatt ggagtttgac ataccgacac
      541 tcgtctgtga gatagaggta ttagcgaccg atcaaatcat caatgaaggg agaagaaaaa
      601 cttacgcctg caggaataaa ttcgccagca atggtagcgc ctccacgggg aacctgtcgc
      661 ggtgaagcac ccgcgaaagg agggaacatg cggagtgact cagtgatgac ggcgttgaga
      721 tacttgagat gccccgttcc tgtcaatgtg atttcgtctt cactggagaa ggctgatcga
      781 acttcttcaa tgaccttggc catggcctcc gggttcttgg ttaggtagta tgtggtgcca
      841 ctgagagcac tggagatggt ctccgcaccc ccaaggatga gagcagtgca gttggatgtg
      901 atttcggtat cagaaagctt ggcgcccttt tcatcgtttc caagcatagc ggtcatatag
      961 tcagggcggc tggcgccaag agcacgacgt ttggcgattt tggcatcagt gagttgctgg
     1021 ttctctttga gtcttctacc gaatcccttg ggcgtgatga atagtaggac aggcaaaaag
     1081 gctctgttga ttctcttcaa gcagttggcg agaataacga atctggtggt ctcgaagatc
     1141 aaagatgccc aggggtgatg gccaccacta tcgagagatc ctaaagccgt ggtcaacttt
     1201 acgcgaacat gtcaacgaac atcacgagaa agattcttac cgaaagactc gccaaatgtc
     1261 aaatcaccta gaagcggaga gtcagcatac atctcatctt ggttgttcga ctgccttcat
     1321 gcactatcca gtaaacactt accgatgata tcaaaagcag tgaaactgta ccatgtttgg
     1381 atatcaatga gcttctggcc accctcacag cgctttctaa gctcagaaag aagcagatca
     1441 acgtaaccct tcagcaaagg ttcttgcttc tggaaggtag cggcggagaa tccgcgagat
     1501 aggatccttc gcatgcgcga gtggtcctca cgggttgtta ctccgagtag gttgtccttg
     1561 aaagcttcat tgaagatggg ctccttggtc atctcaggct ggcctggctt gcggtggccg
     1621 ccaatatcat tccaagcgga cacggactgg aaagccagct catcaggcgc aattcgcaag
     1681 atgggaccat atttcttgtg taaatcgagg atgatatcgt gggatttgcc gctgatgatg
     1741 gcgagggaga cgccccagcg agttacagcc cagaatttag ggcccggaaa cttgctgaga
     1801 ggatgaaagt agagcaggta gatgggattt acgacgaaca cccatgcgaa gaactaatat
     1861 tcaaagtcag ttggcaattc tagttcgtga gagggagtca atacatacag caccaacgat
     1921 aacaaaggct gtgtctcggt tggcgaggtg ccccaaatct acttggggta acactgccat
     1981 aatgggcaaa aaacaacgaa gagaaaaaaa ttccttaacg aagggttgag ctttcggaaa
     2041 aggcgtattc tttatgagga gaaagaagag aaagaggaag agggaaaaga gaaaaaccaa
     2101 gacgttttgt actacgagtt catgcagcag agctcaatgc ttgttacgta catgtatgtt
     2161 gccagccgtg atgaatcctt cacttatgcc gcttacatga ccatgtgggc tcggtgctct
     2221 ccctacagag aaatcagcca cgctcttctg ttcctggaga gagccttgag ctcacaagca
     2281 atcaactcca atgaagggta tctcacgtat cacatcaaaa aagcacaaca gattgggtag
     2341 catgcatgcc tacgagcggg gtaaccgaat cctattccat gtgggcgggg ggccggaaat
     2401 gcatcgattg tatgaacatg gatggatgat gtgatgcaac atacaacata cagcatactc
     2461 ttatcttgct atttgggggg gttcagccaa ggggctgctt gactcgacac tgaatataat
     2521 ggggcggagc tccggaggat gtggaactac aacaccagcc tggcttagac ctgtcatcca
     2581 atcgactgat ttgatgtaat gtcggttgct gttgtctgtt gggtgccggt gtaagtaggc
     2641 ttggtaggga gtaggtgtgc ctgggccctg gccaaaggat ggaaggaaat gccggatccc
     2701 tcgagagatc ggttggtcga tcgacctcgg tgttactcct tctcggagcc atgacggagt
     2761 gctatggcaa gtcggagtat gatgtgtcga ttcccctgtg ttggacccaa atggacccag
     2821 atggagccaa cttcatgttg gttgagggag agtgtattgc ggagctttgg ccaccacgtg
     2881 gtttatataa cctcgctcgc aatcactcta taatcacgca tctcctcatt cttcattcat
     2941 tgcaaagtcg ccaaagtaaa attcatatag ttgttcttcg atttcatacg tcaaaccgcc
     3001 aggatggtta tcaagctgta cggctctgcc atgtccacgg cccgtgtgct ggtcacactt
     3061 cttgaaaagg agctccccta cgagcacatc ctcgttgata tctccaaagg agaccagaat
     3121 aaggaagaat acctgaagct tcagcccttt ggcaaggtgc ccgtgttgga tgacaatggg
     3181 ttcatcatgt acgagagccg agctatctgt cggtatcttg cccggtgagt ttcttacaat
     3241 tgcacaccac aaaatggatc attcatggag atattgctaa tgagaaggat agcaagtacg
     3301 attcaggtac caaattgatc cccgatgtgg atgatcatga ggcgtacggc cgcttcgagc
     3361 aaggctgttc tattgagtac agctactttg ctgccgcagc cgaaaccctg ggaactgagc
     3421 tggtcatcaa aaagtaggtc caaaccaagt cttcaagtta tgagagctgt ctgggaaatg
     3481 gcagaatcaa aattgctgac acaaattggc ccatagatac aaaggactgg gtgagccgga
     3541 catgaccaga gtcgctcagg cggaggccga cttcgacaaa gtcttcttcg agtacgacaa
     3601 gatcctggcc aagcaaaagt acctgacggg cgacgagatc tcactggtgg acctgttcca
     3661 cttgcccaat gcctctgcct tgaaggcatt cggataccag ggaacctttg agaagtaccc
     3721 caacgtgaac aggtggttct ccggcttgca ggcgagggag acgtggatca aggccacagc
     3781 ggaggccaga taagtggctt gaagctgaaa gattgtacat gaagtttatc ctagattcgt
     3841 gatcctacgt aataaatgaa cagtgatcaa aatagctcat tttgtgacag atgatgagtc
     3901 ggtcaggttt tgacatgcat acgtacatac acacctacat ggtgatgact gcatgccaca
     3961 aagcccgggc taaattaaga gttcacgatt tctcaatggt cgacagcaag ttcacagaat
     4021 ggaaagaaat ggaagaagtc tgaccagtga gagactcaag atagcttcag cctcatgcgg
     4081 tgggtgagaa caatttcaat ttgcaccaca tttcgaaccc ctatctttga cgacatccct
     4141 agaacatcaa tcttcacgtt ccaacagtaa attgatatga aaagtacgct atcatgaatt
     4201 atcatcgcag ctagttggca ttctagtccg taaatcttac aaatcgtctc ccaaaaagat
     4261 actcatgcag ttcaaatgaa gtctaatttg cctcgctgaa atatttgaac gactcctcca
     4321 tcgccgcctg aagcaagtgc acatgccccg gcatcggcat atccaagtgg tccgaatcga
     4381 tagacaggca cagagtctcg ccaaggaact tgtcccatcc gttgggtccc aagtccgcag
     4441 cggacttgtg cggaaggccc cacgccacgg cacccagctt ggggtcctcc atgaaccctg
     4501 ggtacgactc ggtggggatg cccttgtcgg ccaggaactt catcaccttc tcgtcgcgag
     4561 aacaacggtc gaccatgccc tttttagccc agatgatagc tgttcgcttg ggtcgttgag
     4621 cgggagtcat gggaggaggg tggtaggctg cgacgcaggc gaagacggcc ttgagatgct
     4681 gctgggtgtt acttgaggcg ttccagagct tatcttggga agcgatggtc tcgtagacct
     4741 tccagccgac ctcgattgtg tcctcaacac ccaaaggacg gggagaacac atatcgatga
     4801 ggagaagact ggagacgacg cgaccggcgg cagcgagttg gcgagacacc tcatagctga
     4861 gcatagctcc gccagagaat cctcccaagt caaagggacc ctcaggctgg cacttaatca
     4921 acgcctcaaa gatgatcttt gcgacgcctt caatgcccac ctgggtggtc agcctgctgg
     4981 ggcaacggag gaaaggcgaa tcaatgccat aaaccggtct cttgtccttg aagggagcca
     5041 ggtggatata cgtagcaatg ctaccagctc catcggcgat caagtagaaa ggctgctttc
     5101 cactcgaaga tcgaccctgg atcaaggtga ttctggcact ggggagggga gaggaatcct
     5161 cgacaaccgc ggacggaacg atcaccagct cctcagactt ctctgaagcc ggagcaggct
     5221 ccttcttctc agaaggcgct cgactcgagc tgcgcgtaga ctctggagtg gcatcgacga
     5281 tggagaactc ggaaaaggtc ttgctgggag gtgtagatgt agaggagcgc gcaaattcgt
     5341 ttcgcagatc tccaatggtg ggataatcta cgacaaaaga ggggaggaga acatcgaggc
     5401 cggttctgct gctgacgccg gcagcgatct caatacccat gatggaatca acgcctgtgt
     5461 agagattgtt agcttttgtt ttgttcaagg tggaaggggg gtttaagggc attgtcaacg
     5521 taccaagttc agccagttcc atgtcatcag tgaagtcaga gacctgagtg ccagtctcct
     5581 tggcgatgct ttcaagaata gtgtggaaca attcgctctc cgacgaagag atcttcttca
     5641 cctctgtctt cacaggctca ggcgccttgg gagccgcctc gacagcagct ttcagggccg
     5701 gttttgactc tgcgggcaca agcactggcg ccttctggtg ggaaacttgc ttcacaggcg
     5761 gtgatgcctt tccaagaagt ctgtccagaa cattgttgct gacctcatgg aatgagagtc
     5821 ccgagcactg cattaccatc ttctccgagt cgaagacgaa caagtcacag ctgactgtgt
     5881 cttcttcctc atgcaaaacg cgagcatagg tgtagtaagt gcgtccagcc tcgagatcag
     5941 cggtctgctc gacgctctca agactctgca tcatgaaggt cgtctgagaa gcagtcttgc
     6001 gggcagggtt ggagttcacg aggaaaccgg caagatgaac tacgctctca ccccagtaag
     6061 gggacgcaaa gaactgagtt ccagccgggt tcttctgaag caccacctcc gcagcagctt
     6121 cgtcaaactc atttgagatg aaggcctcct tgacagactt gaaggtaggg tcataatcaa
     6181 ctgtgctagc gaagagagtg tagaggatac tggggagcat gcggtgacca tttccgctct
     6241 tgacattctt gatcaactcg ttcatacgag ccttgacgaa gtatgagctt ctgttccagc
     6301 tagtttgaag agtctgggca tcacaaatgg tgatctcgca gctaccaaga tcgtatgatg
     6361 catgagagga agaagccttc catgaaacct gcaaggtatc gctggaggcc ttgtctgcaa
     6421 caaccgtggt gagaagctcg ccatcggtgc ctacaagaga ctttgtgagc gggcgcttga
     6481 gagacaggtt gttgattgta agtcttgttt ccacggtatc ctttcggcca ctgtacttca
     6541 gtgcgtactt ggagacggca aggcctgcct cgcagaagac acttccgggg cagatggaca
     6601 catcgcgcat gcgatgaccg tcgaccaagg ccatgaagcc aggatcggag atagcagctc
     6661 gggcagagac atggaggctg ggtgatgatg attcttcaac aatctgttga gcacatgtag
     6721 aaatcctctg tgtttcgaac gagggagcgg gagccaaagc tcgagcagcc ttgttggcct
     6781 cagagtagac aatccagaag tccttgaggt cccatgcata ggcgggcaac ttcacgagct
     6841 tcaagccgcc cttgaatgga gcatgcaccg ccaaccagtc aactgcgaca ccatccttgt
     6901 acgcgccggc gaggcacttg gaaatggatg cccaggggtt ggtatttgcc tccaaagtgg
     6961 acaagatttt gcccggcgag ggtgagagag tcgcccggac aaaggagctg cagatttggc
     7021 tgggtccgat ctccagccag agagggtcag caaacttctc cttcaaggcg ccaagagcac
     7081 cgacgaagtc gacagcttgg cgggtttgct gaccgaggta ggaagcgttg aagacccctg
     7141 aagactccac aatcgaagcg agcagggttg aagcaactgg aatctttggt ggcgagtagg
     7201 ttacaccacc cgcaagaacg atgtaatcct cgagcatggg atccatctgg aaggagtgaa
     7261 atccataggg cacagacaga gccctggctc gtgatgccgt gaaggatgac tggagctcag
     7321 aaatctcatc agtgctgccg ctgataaccg tggcattggg gctattcttg catgcaatct
     7381 cgaaggatga ctgcgggcgc tggtcgatga gctcgcggat ggaggcagca gagcttgata
     7441 ctgccaacat agcgcaggtg tcggcttcgc agcgctccag caggagacgg gcccgattgc
     7501 cgacgaggta gagcagatca gctagagata ggacccctgc gacctggaga gccacatact
     7561 cgcccaggga gtgacccatg actgctgacg gctggatacc agacgccttc cagaatgcgg
     7621 cgagggcgat ctccagcgtg acaacagcga gctgtgtctg catggtgtcc ttggtggtta
     7681 tgtcaacatc tttgttggtg atgatatcca cgtacggggg gaacccgtgc tcctcagaga
     7741 tgctggcaca gaggttgact tcctcgcgga aagcagggca tgtcttgtac aactcggcac
     7801 ccatgccggc gtagtgagag ccctgtcccg tgaatacgaa gacaacgggc gagccccgag
     7861 acgcagttgc atctgccgtg tctgcctcaa gcttggaaat gagctcctcc gttgtggagg
     7921 cactgcaaga gaatctgagg gggtggtgca ttctgcgggc ggtggttgtg tatgcaacat
     7981 cttcgagttt agcatctttg ttcttgcgta gccacttcag gaggttacgc ttattcgcgt
     8041 gatatgagga ttgtgttttg gcagaggaaa cgatgacatg gcttggcctg gggtccgcat
     8101 tttccttgac ggtggagggg aagtcttcca gaatgagaga ggcgttgcca ccctttgaaa
     8161 attattagca ttagaaatac tccagcccgt agatatgact tgtgagaaca cgtactgctg
     8221 cgtcaaagtt attaaggagg atgcgtcgtg gccgctcgcc gatagccttg aactccttcg
     8281 gctcggaggg gatatgaatg ttaagctcag aaagactcgg atactttggg ttgagagtat
     8341 ggggcattcg agcctgaggg ggcataatat ctttctgcaa acaatatgat gagtattcct
     8401 gtgattaatc atggtgttgg gatcaacata cctggaacat ctgtatgcat ttgagcaggg
     8461 aggccatgcc agcagactga atggtaagtc agcatttcat tatgcagtga atcacaagga
     8521 cttctttctt acagcttcag catgcccgac gttcgctttg attccaccaa cagttagggg
     8581 gttattcgcc ttcctcttcc tgaagacatt ggtaacagca ctcatctcgg ccggatcgcc
     8641 aatctgagtt ccagtgccgt gcatctcaac atatgagatc tcatcaggag agactctggc
     8701 gctgtgcata atcttgtgaa acagtctctc ctgggcaccg gcatccgacg tggtgatgga
     8761 tgaagagttg ccggagtggt ttctgcctga accagccacg acagccaaga tgttgtcgtt
     8821 ttgctcgaca gcatcttcga gacgcttcag cacaactgag ccgacaaagt ctgctcggca
     8881 gtaaccatca gcatcatcgc agtaggtttt gcagtttcca gtgtcggaca agacaccaga
     8941 cttgctaaga cttgtccagg agtgaggata cccgacgacg ttggcagcac ccacaacagc
     9001 catgtccaca tctttggata gaagactcac gcaggccagg tgaatagcag aggaggtgga
     9061 ggcacatgca gaatcgagcg agtatgttgg gccctcccac ttgaagtgga aggcgatgcg
     9121 accagcgccg aaggctcttt gcgccccctg cagggtgtag gcatcacaac ccagggtata
     9181 atggctcacc atatgccaat catcgttgga ctggccatag aacgccgcga tcctattagg
     9241 atcaacgtcc ctagtctggc catcagagta tcctgccgtc tcaagagctt cataagtgct
     9301 catcatgaac tgcctgtgac cggggtccat caacagcgcc tcacgaggcg acacgtggaa
     9361 gaagcgggag tcaaagtttc caggcttgtt catgaagcag ccgtattttg tggtggtggt
     9421 gcaaccctcc ccgtgctcgg tacagtagaa ctcattgatg tcgaagcgat ctttgggaat
     9481 ctcttcacaa cgatcctgct tcgccataat gacgtcccag aactcatcaa cattctcgca
     9541 gccaggacca cggccagcca taccgacaat ggcgatgcgg cccgggggga gtttcttcgg
     9601 ctgtaactgc tcaagagtct tatcggtctg gaaaatagcc ttgctgccag cagctttgag
     9661 cgaactcgcc aagtaggggg tgtggctgct aggtccgatg actcggacgt cgacatgacg
     9721 agggccgagg tgagtgttga gttgcgcaat caccttggta atgtccaaag gcttggacaa
     9781 aacttgagtg acgattgctc ttagcatttc tccccagttc tggtaggatg ccacaggatc
     9841 atccattccc cagactttga agtctggcac aatggggtga ctaagaagct cagcactccc
     9901 gacaatgaag tcgaggtcag cctctgtgac tgtgactgtg tgctgaaggg cgtggatgct
     9961 caattcattc ttggggaggt tgcgcacagc gggacactgg tggatgaata ggtccaagac
    10021 tgagggtggc ccaataacgg tgctccatcg gtctcctgtt acgccaacct tagctctctt
    10081 gatggcagga atcccctgtt gcactttcgt taggctaatt tttgtacgat tttaggagat
    10141 gttcctggtc tacttaccat gctggattgg aactgctcaa gcactttgct cagttcctct
    10201 ggtgtaattc ccagcactgc ccagccccaa acgccaggtc ggtcctccat agctcttgat
    10261 cgtaccgaag taaaacggca taatctgaca aatattctcg cagcctcaat gactgcgtca
    10321 tatagagact cgaagtctgt ggatatcgcc agtgctgcga ggttggtgag tcctccagag
    10381 ataccgagtg cttcaggctt ggagccattg aggtccacaa gctgtgattc tttcttcacc
    10441 catcttgatt cacggttagc aacgtcaagc cagccacggc ttacaagcag aacttactgt
    10501 aatagcatgc ctcctctcgc ggcatgtagc aagacagcac gcaccatacc aatctcgtcg
    10561 gtgccatggc ggtatctatc cgccaagtcg agtagtgtag agtattcacc aacactgtct
    10621 tgtaacgcat gatccatgcc ccgggactct tccttgaaga cctttacaag gtcgtcgaga
    10681 aacgtctgta gccatggtat cgtagcggct tgtctgtata gctgatcgag ggaatcaacc
    10741 caggagtctg tctgatctcc aaagtagagg atagtctgtg gtacagtcac catgtttgct
    10801 aaaagacaaa gagacgcaac aaggtggttt gaaagttcaa agtaacatga aagaacggga
    10861 taaagaggga agaaaagagc aatatagagt cggagttacg aaatagcgta tgcaagttgt
    10921 aggctttaag cgatgaggta tgatagaagt ccaggagata aagccttgta atcggatatg
    10981 ataccggccc agggagcaaa caggaagata agcaagtcag cccgcaggca ggtctttcta
    11041 tatattaata catgcgtctc ttgccgatcc cttgctacgg aaagcatgga aagggcttcc
    11101 ggcccggcat cagtcagata cctcacatcc aattacagat agctcaacaa cccatatgcc
    11161 tagatccaga aggagtaaac cgatggagat tgaaggccaa gctaggattg gccgtgtcgc
    11221 tcagtgccta ccgagaccgt gaagccaccc gctgtactgc aaatatatga acggctaact
    11281 atattaatgc gcttcataag catggaagag tggcgccagg tgcaagactc agctgcaaaa
    11341 cgatcctgta tggaaagata aggatctagc gcccgacttg tagggcagac aggaccaggg
    11401 ctcaccttgc acagtctttt tatttcgcga cctctatggc gctcaatgca acgtcgggtg
    11461 gagggcagct tgggcagatc ggagcttcgg ccgtggagtc gtcaacacgg gcactacctg
    11521 ttttgagatg ggctcgaatg ggttcaacgg cacacaccct ccacccttca tgacttcatt
    11581 cccctaagca ctagcccatg atgatgcacg tcctgaatcc cgcgacgata cgtgtaggga
    11641 tctcacggct ataccctggt ctggatagag aaagagccgg cacccgtctt gcagtcagtt
    11701 gtttacctgg ttgcagacat ggccattcac agccgagcga ggggcggcaa caattgtctt
    11761 cttataatgg taagattggg cgactggcca ctgttgttta atcaagtcag gctgtaagga
    11821 caatgataag tctcttttca tgttgtcggg tttcttgcgc ttgtgcatga ctttcggcgt
    11881 tagctattga cggactgacg gactgactta ttcgctgcta ttcaatctcg gcatgtcgtg
    11941 ggaatcccca gtcaactaca gtgtgggcgg tgaagaccta gatctagatc tgggtgcctt
    12001 tctcggaagt ctatcagatt tcgatgggca gattgagccg gcgcactctc tcgaggatga
    12061 atactctggg caatctgggc agggcgccga tgacgacccc gactcggatg gaccgaaagt
    12121 tctgaccatc atggccagca tagatgccat ccaccgtcat ctagagaacg agcgaaaaaa
    12181 ggggaacggg aaggctaatg tggccatcaa gcttaaggat ccgacaatgc gtaagagcat
    12241 aaccttttcg attccggaac tgcaaagccc tacgacaaca gcatcaagtg ccggcagccc
    12301 atcttgtgca ccgttacgat tgccgtcccc agaagccttc gatctgggag aagcaatatt
    12361 ctcacatcct actgccgggt cttcgtttcc agaagaggtc actcccgcag cagaggatga
    12421 tgtgctgtcc agcatagcga gtccttttgc tacgcccgag ggcctttttt ttccccagga
    12481 cgaagatgtg ttaccaagca tagccccgtt gctgaaagca gcaaacttgg cgcatgcaac
    12541 cgaaccttct cttgggctca tatcgcccag agcaactgca tccgagtctt ccatgatgcc
    12601 agacgaagag gcaatggccg acgttgtaca gtaccgcgat ggaactggta caacgccaga
    12661 gagcctgtct ccaggagata tggagcagga tgaatggccc catacagtgt cttcgagaca
    12721 gactcgttct cgtcaggccg ccagagcctg tcagactccc tccaccatgt caactaagga
    12781 taagaaatgc atagattcat cctcctgcag ccttaagcaa atgaacagcc agcaccaaaa
    12841 aagaaattcc atcgagacag cgcccagccg gaccatcaag cgacctcgag tcgagtcgcc
    12901 cgatctcctg actctgattc ctaaccacga tgagtaccag agagtccaag agttgactgc
    12961 tgcactggat ccattactcg catacaagat ggtccgcaat gccagggcga ttctacccca
    13021 gtcggttgcg gaggacatgg cgcactcagc tgacatggag gttgacggcc cccttcacta
    13081 ccaaaataat cagcaatccc cttccagcca agaggaaatt atgcagcagt tttgcgagac
    13141 cgttcgcagg atagagtggg tggaaagagc cgcctttaaa tccatggtgg agtacagagt
    13201 actgttcgtt caactttacc aacactacct gaggcttcag gagattgtgg taaccaggaa
    13261 gggggaaagg agggtgacat tggccaaaga gcaactctac aggacgctgt atcccggcgt
    13321 tgagaagatg acaagcagcg gcctgacgag cgatgaatgg gaaaagttca accggtgcat
    13381 tcgaaggggg aagcagtgga atacaatcgc ctcgaagctg ggcgtaggga ttcttcaaag
    13441 gatgccatcc agcatttgcc attcatgggt ggaacagaag ctccagacaa aggagcagct
    13501 tcatatatgg atagaaatag ttagccttct cgcatagtct cctcgcatag actccgatgc
    13561 acagaatccg atgtatagta cttgtacgga gcagagtccg aagtttagct caatatttgc
    13621 ggccttaagt tttgccgctg taacaattga tatgaaatct cacaaaactc cgcgaccaac
    13681 agccaacagg tgaaacttga actgtgcgcg catctcgtgt ggaccttatc tccgcgatgc
    13741 tctcaacggc ctcctccccc gcccccagcg gactttgatc ggccacagca acagcttggc
    13801 gcaagccagc gatcgagcaa aagaaaaaaa aatagcaaac ctctcagcct ggccctgcca
    13861 agaatacaac acaacgacga tcaaagagaa gtttgcatac gaaagcaaaa gtcatggcac
    13921 gggccactct ctctttgagc gatagcagct cgcaaagact caatacgagt gtaacagcgg
    13981 gcggaaattg ttcctaaatt accagttcgc catatgcacc gtttgcgtcg atgaaacgaa
    14041 gagctggact tgagaagcag ggcttggcag catgagacgt aggtggcaca agcaaggatc
    14101 ctaacacgtg agatccgcgc ctaacggttg tcggcaagtt cgttccagtt ggatcctctt
    14161 ctcccatgtg gcggaaaggg gggacgattg ttggacatgg ttttggggag tggcagtcag
    14221 tttcgagcac aggggcggga agcaggggag aagcgtccgt ggtggtggca tcaaaggtat
    14281 acaaacaagc acctcccccc tcaaaacagg accgaagcgc cctcacagca tgggggtgga
    14341 acaccgaatg ctgacctttc aagcctttac tgggcgccct gtggtgtgta cccctgagtg
    14401 actagagatc cgcataggat tgcggatgcg ataggtcact tacctgaggg aaagaaaata
    14461 cttgtagatg atgggggggt ccacgttcaa atttgaatgg atgccgaggt atttcctctc
    14521 agtattccac ttacgtcact ccgtattgtg aatttgtcga agacttggga cagtcagtcg
    14581 gtcatgagtc agacccagac aacttttgcg gacagggccc gtggggcttg gcatggtaac
    14641 acgagatgag acaacaagga cgaaacgggg atcttcgggt taatgaggtt gggtgagagg
    14701 gtcgtatcgc gcgtgcagca ggtaggtagt atcgagtggc agacatgaag cagtcttgga
    14761 cagtaacaaa agtccacgaa catacacccc gagctgcgaa aagagggaca ctgggttggg
    14821 ttatcgtcgc gataggcaat tgctagtgac agattgactc cgaacgtgag actttgaagg
    14881 attcctgcta gcaaggtcag gcagatgccg gacttgagat caaattgtag ggaacgcctg
    14941 gagttgatgg gcaagacgtt acagtccccg atttagggta gtgcacacca actcacaagg
    15001 ctcggcctgg ggcataagcc gccatcccat ccttcagctc catagcaccc taacagaagt
    15061 gctgacatgt actttgacac gatttgactc tatcgccggt atcagaggcg atgaggaaaa
    15121 atcgatctca tatctagatc tgttcgcatc tagtcaaaga acgtatcttg cattttcttg
    15181 ccatccaaat catttcactt ttccagtttg aactttgttc ctccacagcc agcaagaatg
    15241 agtgcatcca atggcgagat tgttcagagg attgaatctc tgctagcaag cgccaagaag
    15301 ctccagggcg atgaccagta tggccgcttt gggttgctca aggagattga tcttctgtat
    15361 caagacgtgg agcctcccat caatacagtg agttgtaaca cggcatactt ttgacgattt
    15421 gacaacagtt gttggctaat agtttcggta gtttttcaag cagtggactt ccgtaggagc
    15481 atttccatgt aacttgtgtc accaaggtac tgactctcga acagttgacc tttttctctt
    15541 gcatcgatat tgccatcaag ctggggctct ttgagcacat gaagggccgt gaaagtatca
    15601 ctgccaaaga gctcggtgct cttgtcaatg tcgacgacga tgtgattggt atttttcgcc
    15661 ctcagtccta tccccatgta atcacagcgg cgcactgaca ttgatgttgg cacagcccga
    15721 gtgatgagag tgctcgtggc ctctcgattc gtggcctcga agggcgagga tgcctatgcg
    15781 cacacgcaca agtctctggt ctatgtcaag ggtgaacata ccgcagttga ttcgttcaac
    15841 ttgatgtcag cggcacgcct catccgccca gtactccggt cgctaacaat gtcccgcgca
    15901 cagttccctc ttggccgtca gctacatcac aatccccgag tacctcaaga ccagatctgc
    15961 cgatgagctg gtagacatcc gaaagacccc gtatgcctgc gcctacggca tggagggtaa
    16021 gaccttctat gaggtcctct ctaccaaccc tgaccatctg gataccttca acaggtcgat
    16081 gagcgagcct ggtcccgagt ggggcatgtt tccctttgag tctctcagag agaatgtctt
    16141 ggccgagccg gagcgcccgt ttgtggtaga cattggcggc ggaaagggtc aagctcttct
    16201 tcgcatccag gaagagacag gcaaagtgtt tggaacgagc tctcagctaa tcctccagga
    16261 acgacccgat gtgcttgaac agatcaacca agatgacatt gcaggcatta cgaagatgcc
    16321 ctatgacttc cataccaagc agcctgtgaa aggtgaggct ctgttcagcc ctactgatgt
    16381 cgtgggaaat gctaacgcgg tctcccagac gcccatgtct acttcttcag ccaaatcatc
    16441 cataattatc ccgaccacgt ctgccaagac atccttaagc aggccgctgg cgccatgggc
    16501 ccctcgtcgc gtttgcttat tgtggaggct gtcctgcctg cgcaaaccga cgttggcgga
    16561 gatatgggcg cctacctgat tgacgtatgt cgtgaccgta tccgacgccg atgttcagat
    16621 gactaacgga cgatgtttgc agtttgttgg tcttgcgatg ggtggcaagg agcggaccga
    16681 gaaggaattt gcgacgcttc tgggcactgt tggtttggag ctggtcaagg tgtggcatgg
    16741 caaggcgaga catcacgcaa ttgtcgaggc acgattgaaa agagcgtaat ggcccaacga
    16801 tgacgggagt acccagggag aaatggctac cctagacgca cattaaaccg gttttcggat
    16861 ttttatgaag aactccgcat caacgaaatg tgcactcgat ttaaccaatg tccgcatccg
    16921 tccaagccaa ctttgtgcat gtcatccgcc ccacacgcgg ccccaactcc cgcagctcat
    16981 tggccagaag ctctgctttg tttgcacaag gatataacgt gggaatgaat ccaactgcgg
    17041 agtcggaaat tatggtggag gggcgggaat gcaaggttaa gcataaactc cgcagaggct
    17101 tagggccaac tccgcaaaga cgatcccaga tcgggctccg catttccgca actccgcatg
    17161 ggtggtggag tttggcgcta agacaaggcg tcgacagaga ctcggacgga gaaagggggg
    17221 ggggcccgct ccaacggttt gacgtccaat ctggctgcta ctgttgggtc cgccagagaa
    17281 gcaaaggatc gagcctgtcc gctgcgcact accctaccaa gcctttctat acccagtgga
    17341 ggcattggcg tttgtaagga gcctcgaagc ccgcgataac tcagcataaa cctgtcagat
    17401 caacgtgtat taatgatcat aacctagagc tcccttggcc tgtggcctgt cagacaaaag
    17461 ccgcccgacg aaagaggcaa gtcaatggcg tttgccgggc tttcttccac tgccgccaga
    17521 ctcctctcac agcgggaact agttgcggag gatactcaaa ctagtaagct ggcggcacaa
    17581 cacgggagct aatcgaaccc tccccccttt caatcaagaa gagccttcac aactaatcag
    17641 taacttcatc gaatcgcaga aaacacagtg aatcaaagga cgataacgat aagagatcaa
    17701 agaggaagaa gaaaaaacag agatctcatc cttttacccc cctgcccctg cgggttgttg
    17761 taccacaacc aacctggagg agtcgacgga gtttcgagat taagcatcca atcacaacaa
    17821 ctaaggggtg gatcctgcgg cgtttctgtt tattgttatt tatgccaatc gctcaagcat
    17881 tttccttccc tcctcatcta gccctggcag caatcactta cgaaactttt cttggtcgca
    17941 atccgagatg gaaaaacacg cagagccaga gaagtccctc ggggacaagg agttccagga
    18001 aaaggagctc catgagaaac ctgcgccagc agcctccgag gacatcagcg gtgacagctc
    18061 agtcaacaaa gaggatggcc ccgatcccat caacgacaac tacttgagcg gcctcaggct
    18121 cgccgtggtc atgtttgcgc tgtgcatctc caacttcctc gtcgctttgg acaccaccat
    18181 tctcgccacg gccgtcccta agatctcttc cgacttcaac tccctgcagg atgtcgggtg
    18241 gtacacttcc tcgtatctgc tcaccaactg tgcgttccag ctgttctacg gaaagctgta
    18301 tacgcgattc aaggtcaaga ttgtgtttac cgttgccatg atcatcttcg agattggctc
    18361 tctgctttgc ggcgttgcgc caaacagccc tgtcttcatc tttggtcgag ccattgctgg
    18421 tcttggatct gcgggtgctt tctcaggcgg taagtacccc cccctccggc ctcgtagcct
    18481 gctctgagag gactcctttc gctaatttgc ttgtgtagcc ctcatcattg tcatacactc
    18541 agtgcaggcc gagaagcgag cgcaatactc gggtatgatt gtcggtatgt acggtcttgc
    18601 atccgtcgca gcaccgttga ttggtggtgc ttttacggat cacgtcactt ggcgatggtg
    18661 cttctacatt aacctcccct gcggaggtgt cgccattgct ggcctgctgt tcttcttcca
    18721 ttccccacct caggcggctg tcaaggagac cgcggctgga ttgtgggcca agatcgctaa
    18781 gttcgatccg tttggcacat tcttcttctt gtgctctatg atttgcctgc tgttggccct
    18841 gcagatgggt ggctcgacct accccttcac cgatgctcgc atcatcgttc tgctggtctt
    18901 gtttggtctt ctgctggtcg ccttcattgt cgtccagttc ttcgacaaga acgccacgat
    18961 tcctcctaga gtcatgaaga accgttccgt tgcctttggc atgatttaca tgttctgcgt
    19021 gggcgcccag ttcctggtcc tggtcacctt catgccgatt tggttccagg gtgtccgcgc
    19081 catgtcagcc accgactcgg gcatccgctc gcttcccatc ctgctctcca atacattctg
    19141 tgtcgtttta gccggtgccc tggtctccat gacgggatac tacatcccct tcatgtgggc
    19201 gtctgtggtc ctcacctcca ttggtgctgg cctgctcact accctcactg tcgatgcgag
    19261 cacaggcaag tgggtcggat atcagattat tgcaggcatt ggaggcggtc tcggttacca
    19321 gcaaggtatc agcgtggcac agactgtcct gaaagggtca gacatgacca tcggcactgc
    19381 ggtcatggtc tttgtccagc tgcttggagg cactattctc gtttcggctg caaacaatat
    19441 tttggtcacc aggctcgttg agaacctgga gcgccttgct cctcacatca atcctgagat
    19501 catccttcga gccggtgctt cgggaattaa gaccgccgtc agcgaggccg actatccgtt
    19561 tgtcattgag gcatacaaca tcgccttgac caagaccttc cagattgcct tgatcgtctc
    19621 atgtctgggt gcgatcggcg ctgctggtgt tgagtggaag cgaggctcaa agaagggaga
    19681 cagcgacgag cctgccatta tggccgttta ggagtaaaag cttttgtgtt tttctttttt
    19741 tttctatttt tgtttcgtcc aagaaccgac gcatcgtttg gttctggtta tttcttgccg
    19801 tgaagagagg ctcctgtact attactttag atgcctagat cttcctccag ttttcgattt
    19861 gcatacccta ggtaggtatg gacaataata cagaccgatt cagtcataaa agttggccta
    19921 cagtgcataa ccatggatcc attatcacat aaacaagggc acattctctt gtatgcacat
    19981 gcatgtatgt actcttgtta tccaaaccgc agcccgacca ctgtggtttc tacaagtaat
    20041 cggtatctgc tctagttggt aggtaaccga atgtggcaac tttgagaccg aggtgacaat
    20101 gcatcaaagt tcatccatgg tgctgctgct gcggaataaa ttccctgctg gttgtctcag
    20161 tctcagttct acaattccag cgtggtgtgg gctgagttga cactgaaatc ctacaacacc
    20221 ctacctacct acacacccaa gccaccctgt tgagtctctg agtacttgtt ttgttttagt
    20281 tcccgtccta ttcttttcat tgtacgcgga caatgatgat gcagatggag aatctaagcg
    20341 caaaggaccc tgacgagggt ctcggaggtg tatcttgatc ttcggccgac tcccggttac
    20401 agacactgtc gtttacctat tataatgata gactcatccc acagcgctat ggcattctca
    20461 gctatccaac catctcagtt taccgttgcc gctgcaccag taactcattg gcattggcgt
    20521 ttcccaaaat ggcggacaca agtatccagg atgcgatcac caaggctgcg gacatcatgt
    20581 ccacttctga ctttgtcaac aaggacgttt ttctcattat cccaaggatc cagttgatcg
    20641 atgcaccaac cgccgaaaag gtaagagtga cggccgactg tagaccgcag tcgagccctg
    20701 tctgcctctc aactgattca tgtctaacta tctatagtat atccgagact tcaagcccat
    20761 cagcgacttt gctctcgaac aggagccggg cacgctcaaa ttctgcgcac tgcagccgcg
    20821 tggccagggt aaaggcaacg aggtttttgc cttggagcag taaggaaccc ccctccccct
    20881 gcttgggctc ttccctctct gccgctcgca aatgcacgaa ccatgtatat tgacacatgc
    20941 atcacagctt cgactcggca gcctctctgg caaagcatcg agaatgcccc ctcgtcggag
    21001 atatgctaac ttggttgcta acggccaagc ccaatggaga ttaccccatc ccccctctcg
    21061 tccctctcca aatcttggat cgctttgtca ggcctgcttt gaaggcggcc caggatccct
    21121 atgttgtaat gactcaaatt ggctttgagc cagagggggc ctctcagatt gaggcaggga
    21181 tagctgcata tggtcattta gtcacaaaca ccgaagctgt cctgatggtt ctgcccggaa
    21241 aggcagacaa ggaagcttgg gttacgattg cgtatctaga cagacaagcc tatgaggaga
    21301 ggggtcttgt ccaggaaggg ttcgcagagg ggagcgtcaa gagctggaat gagcaccact
    21361 tggagctcaa ggcagggttt ctgctgcagt aagactctag attcggtgga tagtcctctc
    21421 tatcatagat taccaagaat tgtctctttg caaatgaatg aactgacgtc aactccatgt
    21481 tttgttgagg gtcgactctt gtgttcctgt gtaagtgagc attgtgaaga tggggtgcgc
    21541 aatctggcta tgcagccacc gtctggtgct gggtccaacc cctcagttcc ctgcaaggat
    21601 catctcgtat gccgaatcct tgctctaaat ttcggctggg tcatcctttc tgttgccctg
    21661 ttctcctctt gatgtatcaa agcgacctgg gttcaagccg tgtcttgact ctggctatac
    21721 cccccccccc ccccccgctt tgagatgttg ccttttgaaa gcatcgcggc ggagaaggat
    21781 cggggcgtcc atcagcttac agtggcactg atcttgactc cgcatgataa ggcatttgat
    21841 acattgtgtg aaataatttg tatgctaata gctgcatatg ggatgtagaa tccgcatcgg
    21901 aactatagcc tccttcctta gaagagtcca acaacgatac ctagatctgt gtttcccctt
    21961 tattagagag actttcattt gggtaatcat tattgtgata tagaatcttg tcttacatac
    22021 aaattttgtt ggccatctaa acatcttgtt tcaatttccc cagacgtacc tgacaaaaat
    22081 gacgagagca atactgccag acgtgagccc tgactccatt gaccctcagt ttctagagga
    22141 gaaatatgat caagagcgtc tgaagcgtat caacgcagca ggttatgcca agtatagtga
    22201 ggttggagat ggcgaactgg aacgcttcaa agtgacccat cgtctcgagg atgtggcttc
    22261 aagtcgagag cccgtttcgg ttgataccga cgtggtcatc attggcgctg gctatgctgg
    22321 aattctcact gctgtccggc ttgttcaaaa cggtattctc aacttccgaa tcgtggaaaa
    22381 gggcaacggg tttggaggta catggtattg gaatcagtat ccaggtttgt gaacaggtcc
    22441 tttgtggaat ttggctgagt tgctaacatg tcgatttcta ggagctcaat gtgatgtaga
    22501 atcatacatt tacatgcctc ttcttgaaga gactggctac gtaccaacgg agaggtatgc
    22561 tcgaggccca gagatcttga agcatatcaa cttgatagcc aagaaatggg aactcgcacc
    22621 aaagacgcat ttccagagtg aggtctctgc agcagactgg actgcagacc gatggactgt
    22681 caagactcgc caaggcgacg agtttcgttc cagatacctg gtcacagcca ttgggccctt
    22741 ccacagaccc aagctccctg gtgtccctgg catcaactcg ttcaaaggta acactttcca
    22801 ctccagcggc tgggattacg aggccagcgg agggagtgcg accgagaaac tgaccaagtt
    22861 ttcggacaaa accattggca ttattggcac gggggcgact gctgttcaga tgctgccgtt
    22921 tgtcgcgaat tctgccaagg aggtgctcgt ctttcaacgg acgcccgccc ccgtcaatgt
    22981 ccgcaacaat ggccccacgc ctcctgattt tgccaagttt ttggaaccag gctggcagct
    23041 tcgtcgcatg gataacttca acaagatcta tacaggcgaa ccaatcgaca cgtccatagt
    23101 gtcagaggag tggctgtcag caaccctcca ggttctcttc ggcacagagt ctgacaagcc
    23161 aagcgacccc gccgagcttg agcagctcct ggctcgaact gacttccaag tgatggagcg
    23221 aatccgcagg cgagttgacg agaccgtaag cccacctgac gcccctcccc cccctttctc
    23281 cgttccgtct tacatgacat catatgggtc ctgctcacta atccatgact atgtagatta
    23341 aagatccagt gacaagggag cagttgaagc catggtatgc tacaatttgt aagaggccat
    23401 gttttcacga tgagtacctc gagtgcttca acagacccaa tgtcagactg gtcgacacag
    23461 acggcaaggg cgttgatcgc atcaccgagg actcagttgt tgtcgatggc aaggagcatc
    23521 atgttgacgc tctggtattt tgtaccggat ttgagtacct ctctggtgtt gatcgtcacg
    23581 ggggcttcac tgtcactggc aaggatggcg ttactctcac cgagaggtgg acccctggcc
    23641 ccagtaccta ccacggactc tacgttcatg gctttcccaa cttcttctgc cttcaaaccg
    23701 cgcaggctgg cacaaacccg aacttcatgt acacggcaac tactggatca acgcaaattg
    23761 gtcatgttat tgccgagtgc ttgaaggacg gggtccgtga agtccagcct actaagcagg
    23821 ctgaggatga ctgggtgaag atgattctgg aaggaggacg gggcatgatg catttgatga
    23881 gaaattgcac tcctggctac atgaacaacg acggaaatct cgatgagaaa acagccagaa
    23941 gaatgttcta tcctggtggg ccaactgcct ggaggaaact cctcgaggcg tggagggaga
    24001 agggagactt cgagggtctc cagagaacct attagattag aaagacatta gattagactc
    24061 aaattctggt ctgattctct gcgattttgc caagtctgtt gccgtagacc catctagatc
    24121 ctatccttga agccctcgca acaattagtc atcgccacca catgcgccga ccggcggttg
    24181 cgcgcgagga tacatgtact caactcccct tgcttatcat gatacgacta tttcctatcc
    24241 atatggcatc caatatactt agataactat tattaatttc tgcgcatacc caagatctcg
    24301 cataatgttg ggaagtaaat ccttccgaaa agctacgtca cgtacatctt cataaccggt
    24361 agccctacca gtaacgctcc catgttccgg cagggcgcct actctggcaa atctgatcct
    24421 tctgtatccc ggagaagcaa ctcccactat ggattgacaa aaccccgctc ggggcacaag
    24481 cccatcagat ttgaccagct ccaaacggag gagataagcg gcattaaacc cagttgcttc
    24541 cggaagagga tattaccggc ccctcaccca atctgagttc atcgacggaa gaacgggaag
    24601 cgaccaggga cagggcagtc tcatatgact ggtcgccttg cacattggtt cggtgccggt
    24661 gatgagaaag ttcctcgcgg catagggtat tacgttgtct cggccggggg gtacaaggcg
    24721 cttgacatgt tccgccccta gcatctgcct ttttttgccg acaacaacaa acctcgttgc
    24781 ataagcccgt ggcgtttttt tcctactcgg atcaaggtca tacatgccgt ctgctccttc
    24841 gaggatgctg taacacccat ctgtccaaat ctcaaagtgg aatagggcga tggtactaca
    24901 tccgccttca ccttgatgaa ggattgttgg ggatggcaac accattggcc tatctaaagc
    24961 tggcgtgttt gtttttgcac tcagggtacg tgttgtagaa cttcgtatgc ctatgtactc
    25021 attgctatag gattgtcata gctcccgatc ctagactgga gatattcgtg ttgtgagtca
    25081 ggtagtgtct tgaagatctc ggagttgaga gaataggaaa aagatatgtg ctatctagaa
    25141 atgtaacgat aactaaggaa tacattctaa gaaactctag ggattgaacc agaaggaaag
    25201 ggattttacg ttatggttaa ccaaaattac aatggaacta cccaaactgg ccatatcgcg
    25261 actcgaaggg aagcatcaat ggccacctgg ttcattcgta gtggcgtggg atctgaaggc
    25321 tagctgtgta ttggtatcta gtaggattat tgccttgacc gttcaaacat tctttctata
    25381 gttatctaca attgttttac atcgagtaca ttcttccccg tctccacaac cggtcgcccg
    25441 attctagcgt gatatcggag gcaggttgct tgcctacagg gctgtgtctg tatgtgctta
    25501 catgcactga ttaagaggta tcatctatag atccatgtag acatagatac gggttcttgt
    25561 ctatcttcct gggtgaacag catcaactcg gagactctga gtataaatat catatatctg
    25621 gttgcttctt cagagctctc tataggtttc tttttcttca catctcatcc ttactctccc
    25681 acatctctaa gacacaatgc cttctaccag caatccatct cacgtccctg tggccatcat
    25741 cggcctggca tgccgattcc caggcgaggc cacctcacca tcaaaattct gggatcttct
    25801 taagaatgga cgaggtatgt tctttgagct atccctgact cttatgttat cttgaatctt
    25861 gagaagtttt tttatgatat ggctctttgc taacgctctg ccttgaagat gcctactcac
    25921 caaataccga tcgatataac gctgatgcct tttaccatcc caaggcaagc aaccgccaaa
    25981 acgtgctggc aactaagggc ggccacttcc tcaaacagga cccatacgtt tttgacgccg
    26041 ctttctttaa catcacagcc gctgaggcca tctcctttga ccccaagcag cgaattgcca
    26101 tggaagttgt ctacgaggct ctagaaaatg ccggaaagac actacccaag gtggcgggca
    26161 cacaaactgc ttgctatatc ggctcttcca tgagtgatta ccgagacgct gttgtgcgtg
    26221 actttggaaa cagccccaag tatcatatcc tgggaacatg cgaggagatg atttcaaatc
    26281 gtgtgtccca tttcttggat attcacggcc ccagtgccac cattcataca gcctgctcat
    26341 caagtcttgt tgctacacac ttggcttgcc aaagtttgca atctggagag tcagaaatgg
    26401 ccatcgctgg tggtgttggt atgatcatca cccctgatgg taatatgcat cttaacaact
    26461 tgggattctt gaaccccgag ggccactccc ggtcatttga tgagaatgct ggtggttacg
    26521 gtcgtggtga gggttgcggt atcctcatcc tcaagcggct agacagagct ctcgaagatg
    26581 gtgattccat tcgcgccgtc attcgagcct ctggtgtcaa ctctgatggc tggacacagg
    26641 gtgtcaccat gccctccagc caagcccagt ctgcccttat caaatacgta tacgaatcgc
    26701 atggcctgga ttatggtgcg actcaatacg ttgaggctca cgtgagtaaa ttcgatgata
    26761 actatatgat ttgcaagtta gctgacagac aattgaaata gggtactggt accaaagccg
    26821 gtgatcccgc agagattggc gccctccacc gcacaattgg acagggcgcg tccaagtctc
    26881 gaaggctttg gattggcagt gtcaagccaa acgtgagttt agaatacgac gtgaccattt
    26941 gcactttcac cttgctaacc tttgctagat tggccatctt gaagccgccg ccggtgtggc
    27001 tggtatcatt aagggcgtcc tgtccatgga acacggcatg attcctccaa acatttactt
    27061 ctccaagccc aaccctgcca tccctcttga cgagtggaac atggccgtgc ctaccaagtt
    27121 gactccctgg cccgccagcc aaactggtcg ccgtatgagt gtcagcggtt tcggtatggg
    27181 tggtaccaac ggccacgtcg tccttgaggc ctacaagccc caaggaaagc tcaccaacgg
    27241 ccataccaac ggcatcacca atggaatcca caagactcgc cacagcggca agaggctttt
    27301 cgtcctcagc gcccaggatc aagctggctt caagcgtttg ggtaacgccc tggtggagca
    27361 tctcgatgcc ctgggccctg ccgctgccac ccctgagttc ctcgccaacc tctcccacac
    27421 tcttgccgtt ggcagatctg gcttggcttg gaggtccagc atcatcgctg agagcgcccc
    27481 tgatcttcgg gagaagctgg caactgatcc gggtgaggga gccgctcgtt cttcaggcag
    27541 cgagccccgt attgggtaag tttcttgact tgatcaggcc aatgttcgct gctaactttg
    27601 ggaaatagat tcgtcttcac gggtcaaggt gctcagtggg cccgcatggg cgttgagttg
    27661 ttggagcgcc ccgtcttcaa ggcttccgtg attaagtccg cggagacttt gaaggagctc
    27721 ggctgtgaat gggaccctat cgttgagctt tccaagcctc aagctgagtc tcgacttggt
    27781 gttcctgaaa tctcacagcc catctgcaca gtcctacaag tcgccttggt tgatgagttg
    27841 aagcactggg gtgtatcacc ttccaaggtg gtcggtcact ccagtggtga aatcggtgcc
    27901 gcatacagca ttggcgctct ttctcaccgt gacgctgtcg ccgctgctta cttcaggggc
    27961 aagtcttcca acggagccaa gaagcttggt ggtggtatga tggctgttgg gtgctctcgt
    28021 gaggacgctg acaagctcct ctctgagacc aagctcaagg gcggtgttgc taccgtcgca
    28081 tgtgtcaact ccccctccag cgtgaccatc tcaggcgatg ccactgctct cgaggaactc
    28141 cgagttattc tcgaggagaa gagtgtgttt gctcgaagac tcaaggtcga cgttgcctac
    28201 cactctgccc acatgaacgc tgtctttgcc gaatactctg ctgcgattgc ccacattgag
    28261 cccgctcagg cagttgaagg tggaccgatt atggtctcca gtgtcactgg tagcgaagtc
    28321 gactctgagc ttctcggccc ttactactgg acccgtaact tgatctctcc cgtcttattc
    28381 gccgacgctg tcaaggaatt ggttacccct gctgatggcg acggccaaaa caccgtcgat
    28441 ctcctgattg agattggtcc tcacagcgct cttggtggcc ctgttgagca gattctgtcc
    28501 cataacggca tcaagaatgt tgcttacaga tctgctctta ctcgtggcga gaacgctgtt
    28561 gactgcagcc tcaagcttgc tggcgagctc ttccttctcg gcgtgccctt tgagttgcaa
    28621 aaggccaacg gtgactctgg ttctcgcatg ctcactaacc tacctcctta tccttggtaa
    28681 ttatagcccc tattggagtc aaagaaaagc attcaggttt gctaacattg tcataggaac
    28741 cactccaagt cattccgtgc cgactctcgt ctccaccgtg agcatctgga gcagaaattc
    28801 cctactagga gtctcatcgg tgcacctgtc cccatgatgg cagagagcga gtacacatgg
    28861 cgcaacttca tccgtctcgc tgacgagcct tggctccgtg gtcacactgt cggtaccacc
    28921 gttctgtttc ctggtgccgg tatcgtgagc atcatcttgg aagctgctca acagctggtg
    28981 gataccggca agaccgttcg gggcttccga atgcgcgatg tcaacctctt cgccgccatg
    29041 gctctccccg aggacctggc tactgaggtt atcatccaca tccgacctca ccttatctct
    29101 actgttggat caaccgcccc cggtggatgg tgggagtgga ctgtttcctc ctgcgtcgga
    29161 actgaccagc tgcgagacaa tgctcgcggt ctggtagcca ttgactacga agagagccgc
    29221 agcgagcaga tcaacgccga ggacaaagcg ttggttgctt ctcaggtcgc ggactaccac
    29281 aagatcctca gcgaatgccc tgagcattat gctcatgaca agttctacca gcacatgacc
    29341 aaggcctctt ggagctacgg cgagctcttc cagggtgtgg agaatgtccg tcctggatac
    29401 ggaaagacca tctttgacat cagagtcatt gacattggtg agacctttag caagggacaa
    29461 cttgagcgac ctttcctcat caacgctgcc actctcgatg ctgtattcca gagctggctc
    29521 ggcagtacct acaacaacgg tgctttcgag tttgacaagc ccttcgttcc cacctctatt
    29581 ggcgagttgg aaatctctgt caacattccc ggtgatggcg actacctcat gccaggccac
    29641 tgccgctctg agcgatacgg cttcaacgag ttgtctgctg atattgccat cttcgacaag
    29701 gatctgaaga atgtgttcct ttcagtgaag gatttccgaa cttccgagct tgatatggat
    29761 tccggcaagg gagacggaga tgccgctcac gtcgaccctg ccgatatcaa ctcggaggtt
    29821 aagtggaact acgctcttgg cctcctcaag tccgaggaaa tcaccgagct ggtcaccaag
    29881 gtcgccagca atgacaagct cgccgagctt ctccgtctga cacttcacaa caaccctgct
    29941 gccactgtca tcgagcttgt ttctgatgag agcaagatct ctggcgcatc ttctgccaag
    30001 ctgtccaagg gccttatcct ccccagccag atccgttacg tagttgtcaa ccctgaggca
    30061 gcggacgccg actctttctt caaattcttc tcccttggtg aggatggtgc ccctgtcgct
    30121 gctgaaaggg gccccgccga actgttgatc gcctccagcg aagtcactga cgcggctgtc
    30181 cttgagcgcc tgattacctt ggccaagcct gatgccagca ttcttgttgc tgtcaacaac
    30241 aagactaccg ccgctgccct ctcagccaag gcgttccgtg ttgtcaccag catccaggac
    30301 agcaagtcca ttgctctcta cactagcaag aaggcgcctg ccgccgacac ctccaagctc
    30361 gaggccatca tcctcaagcc aaccactgct caacctgccg cccagaattt cgcctccatc
    30421 ctccagaagg cactcgagct ccagggctac tctgtcgttt ctcagccatg gggcaccgac
    30481 atcgacgtca acgatgccaa gggaaagacc tacatttctc tgttggagct tgagcagcct
    30541 ctgctcgaca acctctccaa gtccgacttc gagaacctcc gcgcagtcgt tttgaactgc
    30601 gagcgtctcc tgtgggtcac agcaggtgac aacccatctt tcggcatggt tgatggtttc
    30661 gctcgctgca tcatgagcga aattgccagc accaagttcc aggtcctgca tttgagcgct
    30721 gcaactggtc tgaagtacgg atcttctctc gccacccgca ttctccagtc ggatagcacc
    30781 gacaacgagt accgggaggt cgatggtgct ctccaggtgg cccgtatctt caagagctac
    30841 aacgagaacg agagtctccg ccaccacctc gaggatacca ccagcgttgt gactcttgct
    30901 gaccaggagg atgctctgcg cctcactatt ggcaagcctg gtcttttgga tactttgaag
    30961 tttgtccccg atgagcgtat gctcccacct ctccaggatc acgaggttga aatccaggtc
    31021 aaggctactg gtctgaagta agttccccag catcgtgatt aatgggcaca tgtaaggatg
    31081 tattgctaac agcttcttag cttccgagac atcatggctt gcatgggtct tattcctgtt
    31141 cgatctctgg gccaggaggc cagtggcatc gtcctcagaa ccggtgcgaa ggctaccaac
    31201 ttcaagcctg gcgaccgtgt ttgcaccatg aacgtcggaa cacatgccac caagatccga
    31261 gccgactacc gtgtcatgac aaagatcccc gactccatga cctttgaaga agctgcctcg
    31321 gttgctgttg ttcacaccac cgcctactac gccttcatca ccatcgccaa gcttcgcaag
    31381 ggccagtccg tcttgatcca cgccgccgct ggtggtgttg gccaagcagc cattcagtaa
    31441 gtgttcagaa gaaacctgag aagtattttt tggcaaggac atccaaagtg ctaatacaat
    31501 gaatctaggt tggccaagca tctcggcctc atcacctatg ttaccgtagg tactgaagac
    31561 aagcgccagc tcattcggga gcagtatggc attcccgacg agcacatctt caactcccgt
    31621 gatgccagct tcgtcaaggg tgtccagcgt gttaccaacg gtcgcggtgt cgactgcgtt
    31681 ctcaactctc tatccggtga gctcctgcgt gcttcttggg gatgccttgc tacctttggt
    31741 catttcatcg aaattggtct ccgtgatatc accaacaaca tgcgtcttga catgcgacct
    31801 ttccgcaaga gcacctcctt cacattcatc aacacccaca ctctcttcga ggaagacccc
    31861 gctgcgttgg gagatattct caacgagtcc ttcaagctca tgttcgctgg cgcccttacc
    31921 gctcctagcc ccttgaatgc ctatcccatt ggccaggtcg aggaggcctt ccgaaccatg
    31981 cagcagggca agcaccgcgg taagatggtg ctgtccttct ccgatgacgc aaaggctccc
    32041 gtgttgcgca aagcgaagga ttccttgaaa ctggaccctg acgccactta cctctttgtt
    32101 ggtggtcttg gtggtctggg tcgcagtctt gccaaggagt ttgttgcgtc tggcgcccgc
    32161 aacattgcct tcttatcccg atccggtgac actaccgccc aggccaaggc tatcgtggac
    32221 gaattggctg gccagggtat ccaggtcaag gcctatcgtg gtgatatcgc cagcgaggca
    32281 tccttcctcc aggctatgga gcaatgctct caggatctcc cgcccgtaaa gggtgtgatc
    32341 cagatggcca tggttctccg cgatatcgtc tttgagaaga tgtcgtacga tgagtggacc
    32401 gtccccgttg gccccaaggt ccaaggttca tggaacttgc acaagtactt cagtcatgag
    32461 cgacctcttg acttcatggt catctgctcc tcaagctccg gtatctacgg ttatcccagt
    32521 caggctcaat acgccgctgg caacacttac caggatgcct tggctcacta ccgtcgctct
    32581 cagggcctga acgccatctc cgtcaacttg ggtatcatgc gagatgtcgg tgtcctggct
    32641 gagacgggta ccactggtaa catcaagctc tgggaagagg tcttgggcat ccgcgagcct
    32701 gccttccacg ctctcatgaa gagcttgatc aaccatcagc agcgtgggtc tggggactac
    32761 ccggcgcagg tctgcactgg tcttggtact gctgacatta tggctactca cggcctggcc
    32821 cggcccgagt atttcaatga cccccgtttt ggaccccttg ccgtcaccac tgtcgcgacc
    32881 gatgcttcag ctgacggcca gggctctgct gtctcgctcg cctctaggct ctccaaggtt
    32941 tccaccaagg atgaagctgc cgagatcatt accgatgctc tggtcaacaa gacggcagac
    33001 atcctgcaga tgcccccctc tgaagtcgac cccggccgac ctctgtaccg ttatggtgtt
    33061 gactcccttg tggcgcttga ggtgcgaaac tggatcacaa gggagatgaa ggcgaacatg
    33121 gcgctgctgg agattctggc agccgtcccc attgagagct tcgctgtcaa gattgctgag
    33181 aagagcaagt tggttactgt ttaaggcgtt tacggagggg gcgggatggt tccgaaggac
    33241 tcaaggttgc tttgctattt tctttttggt taaggggttt agggttttag tgatcttacg
    33301 cgtatcatga ttgtgcttta cttgttaagg atagtttcta gaacaatgga tctgatttct
    33361 cagtatttgc ctcattggga tgccattttc cgacgcagag tgagacattt gtccactgga
    33421 aactccgagc actcactgca agtagcctct ttggcgtaaa cggaaacgag tttgacgatg
    33481 gttccaggac gaagaaaaac ccacccgtgg cgcgtgggga atgtaatttc ggaacaaagg
    33541 cgaatagcct ctcggtgtgc aaagcccaat atgagaaaac atgttatacc tagtgatcag
    33601 tgatcatggg gaactcagct gctagtgaag atcgtgagat ccatctgact cggcctgtcg
    33661 gcctcgccaa ttgaacatca aatgctactt gtattccgta tgtggctgaa agaggaggtc
    33721 tggtgtttgg gagatctgca catacggagt acgacagagg aagtcctgcg gagaatggga
    33781 gaagccaacc acccatcagg gctggctact tgcggcttgt gttgacacga cgttcgatgg
    33841 gctacaagta agttgtaact actccgcaga ctttctagag gagagcccgg cgggtttact
    33901 ccttggtcct gactcctgag tgcctggcga cgaacactca cttacccgcg aacgtgtttc
    33961 accgaaactg gatacatcca tcgggacaac atttgtcgaa ttacccgcgg ggggcgcatg
    34021 gacgataatt ttgattcggc cagatgtccg acccattctc cgagatggca attccttttc
    34081 aataaaaagg gttgggttgg accttgggaa ctggcagaaa catctgtcgg catggattct
    34141 gctgcgcgtg cttccgcgag accttccaga atccttccac catgttctgc ataataagag
    34201 cccagctatt attattatta cacttgcttg tactggctct gctgttggtt ggcacagttt
    34261 gcaacgctca cccccaacat ggccatccat cggagctgga gccactagct ctcaaaaggg
    34321 gtggctcgcc tcgagatgat ggcaatactc tggcgccgcg gtgcagatgc gtaagaatat
    34381 cctaagagcg tctcggcgcg tagataacct gtttcttggc tgttcgtttt gcgctgacgc
    34441 tctaggaaga tacctggcga ggcgtgctgg ccatccaccc agatctggga ttcgttcaac
    34501 aggacgatcg gcggcagcct gatcaagacc gcacccctcg cagagtcgtg ctaccctggc
    34561 ccaaaaaaga acaccaggaa atgtgccgtc gtcagtagga aatggacaga tcaggacttt
    34621 cagacggata gccctgtagg acgaacgtat ccgtacaaca tcacatgcgc ccccgtcaac
    34681 tacttcgccg gccaacgccc aacgacctgc agcctgggac agcttccggt gtacgcaatc
    34741 gacgcaagga ctcgtcaatc tgtggcacag ggactgcgct tcgccaagga caataacctc
    34801 cgagtcactg tcgtcagtac gggccacgac ttgctaggca gggcggatgg ctatggaagt
    34861 ctcgagattt ggctccgaca tcataggaac gagattcgct tcgagagaca gtacatggca
    34921 acggatgggt gtcgcgagtc tggctggacc ggcagcgcga ttgatatcga cggcgcatac
    34981 cagtggcgag acgtccatat caaggccagg gccaacaatg tgatagttgt tggaggcggc
    35041 tcggtgtcac ccggtgctat cggaggctgg ccatccggag ggggccacgg tcctgcgtcg
    35101 cgcaactacg gactcggcgc ggatcagatc cttgaagctg aagtgatgct cgccgacggc
    35161 tcagtcgttc tcgcaaacca ctgccaacac accgacctct tccgtgccct caggggaggc
    35221 ggtcctggct tcggcgtcgt gctcaaaact aagattaaag cctatcccaa tgtcgcttcg
    35281 gtatcggtgc atcatctcac catcacaccg atccgccaaa cgccaaacaa ttccgatctg
    35341 ttggacgcgg tagctgtttt gatgcaggct tatccgaaac tcagcgacga tggatacgcc
    35401 ggatatgcct tctggctccg caactgcaaa tcgttcttta ttggaagcgc gaagtccggg
    35461 taccgccacg ggatttggat gattggaaag acaaccgagg aggctgaaca ctcattcgcc
    35521 cctgtacgag aggctttgga caaattcaag tccaagctga ccatctcgga gtcttacatg
    35581 acgtataacg actactggtc gttttataca tctgaatcgg ggctgtacga atctgttggg
    35641 acaacatcag tgttgacttc gcgccttatc gatcgacctg ctgtggagga ttacaatcga
    35701 gttcgtgagg ctgttgaagt tattggtggc aaaccggaag actatgccac caacgtgatg
    35761 atgttggtct ccaacggaca agtctttgca gacgcggcag acaagtcatc gggattaaac
    35821 ccagcctggc gtgtatctcc atacgtggtc atcagcagcc gaggcatacc catggttgtc
    35881 gatcaagcat cacgcaaaga ggtagcagac gacatcacat acgtcaaagg ggccgccttg
    35941 cagaaactcg cccccaatac ggggggctac atgaacgagg gtgacagaaa tgaccccaac
    36001 tacatcaaga acttcttcgg gaccatctat cccacgcatc tcgccacgaa gaagaaatac
    36061 gacccgtggg gcttatttta ctgtccgacg tgtgtcggtg cagagctgtt tgaggagact
    36121 tctcgagggg aactgtgtag gcgatgataa cgacttttat gacgcatcat agaattatca
    36181 cggttggcgt ttgctttttt tgaaatatga atatcgagca tttagtaggg atgggtatgc
    36241 atcaagtgag ccttgattgt aaaacaagtc aaata
//
