LOCUS       BGC0000077             42765 bp    DNA     linear   PLN 12-AUG-2008
DEFINITION  Hypomyces subiculosus strain DSM11932 hypothemycin gene cluster,
            complete sequence; and oxidoreductase gene, complete cds.
ACCESSION   BGC0000077
VERSION     BGC0000077
KEYWORDS    .
SOURCE      Hypomyces subiculosus
  ORGANISM  Hypomyces subiculosus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae;
            Hypomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 12:45:11
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..42765
                     /db_xref="taxon:193393"
                     /mol_type="genomic DNA"
                     /organism="Hypomyces subiculosus"
                     /strain="DSM 11932"
     protocluster    1..42765
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[6150:35072]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6151..35072
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..42765
                     /SMILES="CC(=O)C([*])C(-O)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..42765
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000077"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..42765
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1873..3922)
                     /gene="Hpm1"
     mRNA            complement(join(1873..2330,2403..2412,2474..3048,
                     3109..3135,3211..3721,3777..3922))
                     /gene="Hpm1"
                     /product="cytochrome P450"
     misc_feature    1873..>38015
                     /note="hypothemycin gene cluster"
     CDS             complement(join(2017..2330,2403..2412,2474..3048,
                     3109..3135,3211..3721,3777..3848))
                     /codon_start=1
                     /gene="Hpm1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 364.4; E-value:
                     1.5e-110)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450"
                     /protein_id="ACD39760.1"
                     /sec_met_domain="p450 (E-value: 1.4e-74, bitscore: 240.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVLPQVDLGHLANRDTAFVIVGAFFAWVFVVNPIYLLYFHPLSK
                     FPGPKFWAVTRWGVSLAIISGKSHDIILDLHKKYGPILRIAPDELAFQSVSAWNDIGGH
                     RKPGQPEMTKEPIFNEAFKDNLLGVTTREDHSRMRRILSRGFSAATFQKQEPLLKGYVD
                     LLLSELKKRCEGGQKLIDIQTWYSFTAFDIIGDLTFGESFGSLDSGGHHPWASLIFETT
                     RFVILANCLKRINRAFLPVLLFITPKGFGRRLKENQQLTDAKIAKRRALGASRPDYMTA
                     MLGNDEKGAKLSDTEITSNCTALILGGAETISSALSGTTYYLTKNPEAMAKVIEEVRSA
                     FSSEDEITLTGTGHLKYLNAVITESLRMFPPFAGASPRQVPRGGATIAGEFIPAGTSVG
                     IWHWSMARCPDFFTHANEFHPERWLDDPRFDNDKKDASQPFAVGPRNCIGMNLTYVELR
                     LILARLFWNFDIKLDKSCDNWVDDMVEYFGWEKIPLMVSLTPRS"
     gene            4797..5742
                     /gene="hpm2"
     mRNA            join(4797..5092,5161..5301,5385..5742)
                     /gene="hpm2"
                     /product="glutathione-S-transferase"
     CDS             join(4872..5092,5161..5301,5385..5661)
                     /codon_start=1
                     /gene="hpm2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1193:glutathione S-transferase (Score: 140.2; E-value:
                     1.1e-42)"
                     /gene_kind="biosynthetic-additional"
                     /product="glutathione-S-transferase"
                     /protein_id="ACD39761.1"
                     /sec_met_domain="GST_N_3 (E-value: 2.1e-20, bitscore: 62.5,
                     seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="GST_C (E-value: 3.9e-13, bitscore: 39.0,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVIKLYGSAMSTARVLVTLLEKELPYEHILVDISKGDQNKEEYLK
                     LQPFGKVPVLDDNGFIMYESRAICRYLARKYDSGTKLIPDVDDHEAYGRFEQGCSIEYS
                     YFAAAAETLGTELVIKKYKGLGEPDMTRVAQAEADFDKVFFEYDKILAKQKYLTGDEIS
                     LVDLFHLPNASALKAFGYQGTFEKYPNVNRWFSGLQARETWIKATAEAR"
     gene            complement(6046..12709)
                     /gene="hpm3"
     mRNA            complement(join(6046..7322,7392..10020,10084..10242,
                     10300..10344,10401..11963,12026..12311,12366..12709))
                     /gene="hpm3"
                     /product="non-reducing polyketide synthase"
     CDS             complement(join(6151..7322,7392..10020,10084..10242,
                     10300..10344,10401..11963,12026..12311,12366..12661))
                     /NRPS_PKS="Domain: SAT (8-246). E-value: 1.1e-55. Score:
                     180.6. Matches aSDomain: nrpspksdomains_hpm3_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (367-795). E-value:
                     1e-135. Score: 444.8. Matches aSDomain:
                     nrpspksdomains_hpm3_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (888-1183). E-value: 2.4e-83.
                     Score: 271.8. Matches aSDomain:
                     nrpspksdomains_hpm3_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1260-1577). E-value: 6.7e-94. Score:
                     306.6. Matches aSDomain: nrpspksdomains_hpm3_PT.1"
                     /NRPS_PKS="Domain: ACP (1634-1697). E-value: 3e-11. Score:
                     35.4. Matches aSDomain: nrpspksdomains_hpm3_ACP.1"
                     /codon_start=1
                     /gene="hpm3"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 59.9; E-value:
                     3.1e-18)"
                     /gene_kind="biosynthetic"
                     /product="non-reducing polyketide synthase"
                     /protein_id="ACD39762.1"
                     /sec_met_domain="itr_KS (E-value: 1.8e-141, bitscore:
                     461.1, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.3e-84, bitscore: 271.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.2e-11, bitscore:
                     33.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTVPQTILYFGDQTDSWVDSLDQLYRQAATIPWLQTFLDDLVKV
                     FKEESRGMDRALQDSVGEYSTLLDLADRYRHGTDEIGMVRAVLLHAARGGMLLQWVKKE
                     SQLVDLNGSKPEALGISGGLTNLAALAISTDFESLYDAVIEAARIFVRLCRFTSVRSRA
                     MEDRPGVWGWAVLGITPEELSKVLEQFQSSMGIPAIKRAKVGVTGDRWSTVIGPPSVLD
                     LFIHQCPAVRNLPKNELSIHALQHTVTVTEADLDFIVGSAELLSHPIVPDFKVWGMDDP
                     VASYQNWGEMLRAIVTQVLSKPLDITKVIAQLNTHLGPRHVDVRVIGPSSHTPYLASSL
                     KAAGSKAIFQTDKTLEQLQPKKLPPGRIAIVGMAGRGPGCENVDEFWDVIMAKQDRCEE
                     IPKDRFDINEFYCTEHGEGCTTTTKYGCFMNKPGNFDSRFFHVSPREALLMDPGHRQFM
                     MSTYEALETAGYSDGQTRDVDPNRIAAFYGQSNDDWHMVSHYTLGCDAYTLQGAQRAFG
                     AGRIAFHFKWEGPTYSLDSACASTSSAIHLACVSLLSKDVDMAVVGAANVVGYPHSWTS
                     LSKSGVLSDTGNCKTYCDDADGYCRADFVGSVVLKRLEDAVEQNDNILAVVAGSGRNHS
                     GNSSSITTSDAGAQERLFHKIMHSARVSPDEISYVEMHGTGTQIGDPAEMSAVTNVFRK
                     RKANNPLTVGGIKANVGHAEASAGMASLLKCIQMFQKDIMPPQARMPHTLNPKYPSLSE
                     LNIHIPSEPKEFKAIGERPRRILLNNFDAAGGNASLILEDFPSTVKENADPRPSHVIVS
                     SAKTQSSYHANKRNLLKWLRKNKDAKLEDVAYTTTARRMHHPLRFSCSASTTEELISKL
                     EADTADATASRGSPVVFVFTGQGSHYAGMGAELYKTCPAFREEVNLCASISEEHGFPPY
                     VDIITNKDVDITTKDTMQTQLAVVTLEIALAAFWKASGIQPSAVMGHSLGEYVALQVAG
                     VLSLADLLYLVGNRARLLLERCEADTCAMLAVSSSAASIRELIDQRPQSSFEIACKNSP
                     NATVISGSTDEISELQSSFTASRARALSVPYGFHSFQMDPMLEDYIVLAGGVTYSPPKI
                     PVASTLLASIVESSGVFNASYLGQQTRQAVDFVGALGALKEKFADPLWLEIGPSQICNS
                     FVRATLSPSPGKILSTLEANTNPWASIAKCLAGAYKDGVAVDWLAVHAPFKGGLKLVKL
                     PAYAWDLKDFWIVYSEANKAARALAPAPSFETQRISTCAQQIVEESSSPSLHVSARAAI
                     SDPGFMALVDGHRMRDVSICPGSVFCEAGLAVSKYALKYSGRKDTVETRLTINNLSLKR
                     PLTKSLVGTDGELLTTVVADKASSDTLQVSWKASSSHASYDLGSCEITICDAQTLQTSW
                     NRSSYFVKARMNELIKNVKSGNGHRMLPSILYTLFASTVDYDPTFKSVKEAFISNEFDE
                     AAAEVVLQKNPAGTQFFASPYWGESVVHLAGFLVNSNPARKTASQTTFMMQSLESVEQT
                     ADLEAGRTYYTYARVLHEEEDTVSCDLFVFDSEKMVMQCSGLSFHEVSNNVLDRLLGKA
                     SPPVKQVSHQKAPVLVPAESKPALKAAVEAAPKAPEPVKTEVKKISSSESELFHTILES
                     IAKETGTQVSDFTDDMELAELGVDSIMGIEIAAGVSSRTGLDVLLPSFVVDYPTIGDLR
                     NEFARSSTSTPPSKTFSEFSIVDATPESTRSSSRAPSEKKEPAPASEKSEELVIVPSAV
                     VEDSSPLPSARITLIQGRSSSGKQPFYLIADGAGSIATYIHLAPFKDKRPVYGIDSPFL
                     RCPSRLTTQVGIEGVAKIIFEALIKCQPEGPFDLGGFSGGAMLSYEVSRQLAAAGRVVS
                     SLLLIDMCSPRPLGVEDTIEVGWKVYETIASQDKLWNASSNTQQHLKAVFACVAAYHPP
                     PITPAQRPKRTAIIWAKKGMVDRCSRDEKVMKFLADKGIPTESYPGFMEDPKLGAVAWG
                     LPHKSAADLGPNGWDKFLGETLCLSIDSDHLDMPMPGHVHLLQAAMEESFKYFSEAN"
     CDS_motif       complement(6703..6777)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0006"
                     /evalue="5.30E-07"
                     /label="NRPS-te1"
                     /locus_tag="hpm3"
                     /protein_end="1866"
                     /protein_start="1841"
                     /score="22.2"
                     /tool="antismash"
                     /translation="QPEGPFDLGGFSGGAMLSYEVSRQL"
     aSDomain        complement(join(7210..7322,7392..7467))
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_ACP.1"
                     /evalue="3.00E-11"
                     /label="hpm3_ACP.1"
                     /locus_tag="hpm3"
                     /protein_end="1697"
                     /protein_start="1634"
                     /score="35.4"
                     /tool="antismash"
                     /translation="ILESIAKETGTQVSDFTDDMELAELGVDSIMGIEIAAGVSSRTGL
                     DVLLPSFVVDYPTIGDLR"
     aSModule        complement(7210..11444)
                     /complete
                     /domains="nrpspksdomains_hpm3_PKS_KS.1"
                     /domains="nrpspksdomains_hpm3_PKS_AT.1"
                     /domains="nrpspksdomains_hpm3_PT.1"
                     /domains="nrpspksdomains_hpm3_ACP.1"
                     /iterative
                     /locus_tags="hpm3"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(7417..7449)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0005"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="hpm3"
                     /protein_end="1651"
                     /protein_start="1640"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="KETGTQVSDFT"
     aSDomain        complement(7639..8589)
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_PT.1"
                     /evalue="6.70E-94"
                     /label="hpm3_PT.1"
                     /locus_tag="hpm3"
                     /protein_end="1577"
                     /protein_start="1260"
                     /score="306.6"
                     /tool="antismash"
                     /translation="STCAQQIVEESSSPSLHVSARAAISDPGFMALVDGHRMRDVSICP
                     GSVFCEAGLAVSKYALKYSGRKDTVETRLTINNLSLKRPLTKSLVGTDGELLTTVVADK
                     ASSDTLQVSWKASSSHASYDLGSCEITICDAQTLQTSWNRSSYFVKARMNELIKNVKSG
                     NGHRMLPSILYTLFASTVDYDPTFKSVKEAFISNEFDEAAAEVVLQKNPAGTQFFASPY
                     WGESVVHLAGFLVNSNPARKTASQTTFMMQSLESVEQTADLEAGRTYYTYARVLHEEED
                     TVSCDLFVFDSEKMVMQCSGLSFHEVSNNVLDRLLG"
     aSDomain        complement(8821..9705)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_PKS_AT.1"
                     /evalue="2.40E-83"
                     /label="hpm3_PKS_AT.1"
                     /locus_tag="hpm3"
                     /protein_end="1183"
                     /protein_start="888"
                     /score="271.8"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFTGQGSHYAGMGAELYKTCPAFREEVNLCASISEEHGFPPYVDI
                     ITNKDVDITTKDTMQTQLAVVTLEIALAAFWKASGIQPSAVMGHSLGEYVALQVAGVLS
                     LADLLYLVGNRARLLLERCEADTCAMLAVSSSAASIRELIDQRPQSSFEIACKNSPNAT
                     VISGSTDEISELQSSFTASRARALSVPYGFHSFQMDPMLEDYIVLAGGVTYSPPKIPVA
                     STLLASIVESSGVFNASYLGQQTRQAVDFVGALGALKEKFADPLWLEIGPSQICNSFVR
                     ATLSPSPGKILSTL"
     CDS_motif       complement(9352..9468)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0004"
                     /evalue="7.70E-17"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="hpm3"
                     /protein_end="1006"
                     /protein_start="967"
                     /score="53.4"
                     /tool="antismash"
                     /translation="GIQPSAVMGHSLGEYVALQVAGVLSLADLLYLVGNRARL"
     CDS_motif       complement(9655..9702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0003"
                     /evalue="1.30E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="hpm3"
                     /protein_end="905"
                     /protein_start="889"
                     /score="17.7"
                     /tool="antismash"
                     /translation="FTGQGSHYAGMGAELY"
     aSDomain        complement(join(9985..10020,10084..10242,10300..10344,
                     10401..11444))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.00E-135"
                     /label="hpm3_PKS_KS.1"
                     /locus_tag="hpm3"
                     /protein_end="795"
                     /protein_start="367"
                     /score="444.8"
                     /tool="antismash"
                     /translation="IAIVGMAGRGPGCENVDEFWDVIMAKQDRCEEIPKDRFDINEFYC
                     TEHGEGCTTTTKYGCFMNKPGNFDSRFFHVSPREALLMDPGHRQFMMSTYEALETAGYS
                     DGQTRDVDPNRIAAFYGQSNDDWHMVSHYTLGCDAYTLQGAQRAFGAGRIAFHFKWEGP
                     TYSLDSACASTSSAIHLACVSLLSKDVDMAVVGAANVVGYPHSWTSLSKSGVLSDTGNC
                     KTYCDDADGYCRADFVGSVVLKRLEDAVEQNDNILAVVAGSGRNHSGNSSSITTSDAGA
                     QERLFHKIMHSARVSPDEISYVEMHGTGTQIGDPAEMSAVTNVFRKRKANNPLTVGGIK
                     ANVGHAEASAGMASLLKCIQMFQKDIMPPQARMPHTLNPKYPSLSELNIHIPSEPKEFK
                     AIGERPRRILLNNFDAAGGNASLILEDFP"
     CDS_motif       complement(10494..10541)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0002"
                     /evalue="2.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="hpm3"
                     /protein_end="684"
                     /protein_start="668"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YVEMHGTGTQIGDPAE"
     CDS_motif       complement(11613..11681)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm3_0001"
                     /evalue="7.40E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="hpm3"
                     /protein_end="311"
                     /protein_start="288"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="GEMLRAIVTQVLSKPLDITKVIA"
     aSDomain        complement(join(11808..11963,12026..12311,12366..12637))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm3_SAT.1"
                     /evalue="1.10E-55"
                     /label="hpm3_SAT.1"
                     /locus_tag="hpm3"
                     /protein_end="246"
                     /protein_start="8"
                     /score="180.6"
                     /tool="antismash"
                     /translation="LYFGDQTDSWVDSLDQLYRQAATIPWLQTFLDDLVKVFKEESRGM
                     DRALQDSVGEYSTLLDLADRYRHGTDEIGMVRAVLLHAARGGMLLQWVKKESQLVDLNG
                     SKPEALGISGGLTNLAALAISTDFESLYDAVIEAARIFVRLCRFTSVRSRAMEDRPGVW
                     GWAVLGITPEELSKVLEQFQSSMGIPAIKRAKVGVTGDRWSTVIGPPSVLDLFIHQCPA
                     VRNLPKNELSIHALQH"
     gene            <13801..>15405
                     /gene="hpm4"
     mRNA            <13801..>15405
                     /gene="hpm4"
                     /product="hypothetical protein"
     CDS             13801..15405
                     /codon_start=1
                     /gene="hpm4"
                     /product="hypothetical protein"
                     /protein_id="ACD39763.1"
                     /transl_table=11
                     /translation="MSWESPVNYSVGGEDLDLDLGAFLGSLSDFDGQIEPAHSLEDEYS
                     GQSGQGADDDPDSDGPKVLTIMASIDAIHRHLENERKKGNGKANVAIKLKDPTMRKSIT
                     FSIPELQSPTTTASSAGSPSCAPLRLPSPEAFDLGEAIFSHPTAGSSFPEEVTPAAEDD
                     VLSSIASPFATPEGLFFPQDEDVLPSIAPLLKAANLAHATEPSLGLISPRATASESSMM
                     PDEEAMADVVQYRDGTGTTPESLSPGDMEQDEWPHTVSSRQTRSRQAARACQTPSTMST
                     KDKKCIDSSSCSLKQMNSQHQKRNSIETAPSRTIKRPRVESPDLLTLIPNHDEYQRVQE
                     LTAALDPLLAYKMVRNARAILPQSVAEDMAHSADMEVDGPLHYQNNQQSPSSQEEIMQQ
                     FCETVRRIEWVERAAFKSMVEYRVLFVQLYQHYLRLQEIVVTRKGERRVTLAKEQLYRT
                     LYPGVEKMTSSGLTSDEWEKFNRCIRRGKQWNTIASKLGVGILQRMPSSICHSWVEQKL
                     QTKEQLHIWIEIVSLLA"
     gene            17061..18776
                     /gene="hpm5"
     mRNA            join(17061..17255,17320..17340,17393..17516,17584..17713,
                     17772..18220,18277..18452,18511..18776)
                     /gene="hpm5"
                     /product="O-methyltransferase"
     CDS             join(17106..17255,17320..17340,17393..17516,17584..17713,
                     17772..18220,18277..18452,18511..18657)
                     /codon_start=1
                     /gene="hpm5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 163.7; E-value:
                     1.1e-49)"
                     /gene_kind="biosynthetic-additional"
                     /product="O-methyltransferase"
                     /protein_id="ACD39764.1"
                     /transl_table=11
                     /translation="MSASNGEIVQRIESLLASAKKLQGDDQYGRFGLLKEIDLLYQDVE
                     PPINTFFKQWTSLTFFSCIDIAIKLGLFEHMKGRESITAKELGALVNVDDDVIARVMRV
                     LVASRFVASKGEDAYAHTHKSLVYVKGEHTAVDSFNLISLLAVSYITIPEYLKTRSADE
                     LVDIRKTPYACAYGMEGKTFYEVLSTNPDHLDTFNRSMSEPGPEWGMFPFESLRENVLA
                     EPERPFVVDIGGGKGQALLRIQEETGKVFGTSSQLILQERPDVLEQINQDDIAGITKMP
                     YDFHTKQPVKDAHVYFFSQIIHNYPDHVCQDILKQAAGAMGPSSRLLIVEAVLPAQTDV
                     GGDMGAYLIDFVGLAMGGKERTEKEFATLLGTVGLELVKVWHGKARHHAIVEARLKRA"
     gene            <19816..>21579
                     /gene="hpm6"
     mRNA            join(<19816..20317,20387..>21579)
                     /gene="hpm6"
                     /product="major facilitator superfamily transporter"
     CDS             join(19816..20317,20387..21579)
                     /codon_start=1
                     /gene="hpm6"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 344.2; E-value:
                     1.5e-104)"
                     /gene_kind="transport"
                     /product="major facilitator superfamily transporter"
                     /protein_id="ACD39765.1"
                     /transl_table=11
                     /translation="MEKHAEPEKSLGDKEFQEKELHEKPAPAASEDISGDSSVNKEDGP
                     DPINDNYLSGLRLAVVMFALCISNFLVALDTTILATAVPKISSDFNSLQDVGWYTSSYL
                     LTNCAFQLFYGKLYTRFKVKIVFTVAMIIFEIGSLLCGVAPNSPVFIFGRAIAGLGSAG
                     AFSGALIIVIHSVQAEKRAQYSGMIVGMYGLASVAAPLIGGAFTDHVTWRWCFYINLPC
                     GGVAIAGLLFFFHSPPQAAVKETAAGLWAKIAKFDPFGTFFFLCSMICLLLALQMGGST
                     YPFTDARIIVLLVLFGLLLVAFIVVQFFDKNATIPPRVMKNRSVAFGMIYMFCVGAQFL
                     VLVTFMPIWFQGVRAMSATDSGIRSLPILLSNTFCVVLAGALVSMTGYYIPFMWASVVL
                     TSIGAGLLTTLTVDASTGKWVGYQIIAGIGGGLGYQQGISVAQTVLKGSDMTIGTAVMV
                     FVQLLGGTILVSAANNILVTRLVENLERLAPHINPEIILRAGASGIKTAVSEADYPFVI
                     EAYNIALTKTFQIALIVSCLGAIGAAGVEWKRGSKKGDSDEPAIMAV"
     gene            23886..25953
                     /gene="hpm7"
     mRNA            join(23886..24292,24350..25113,25205..25953)
                     /gene="hpm7"
                     /product="flavin-dependent monooxygenase"
     CDS             join(23947..24292,24350..25113,25205..25903)
                     /codon_start=1
                     /gene="hpm7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 413.1; E-value: 3.1e-125)"
                     /gene_kind="biosynthetic-additional"
                     /product="flavin-dependent monooxygenase"
                     /protein_id="ACD39766.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.6e-13, bitscore:
                     39.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRAILPDVSPDSIDPQFLEEKYDQERLKRINAAGYAKYSEVGDG
                     ELERFKVTHRLEDVASSREPVSVDTDVVIIGAGYAGILTAVRLVQNGILNFRIVEKGNG
                     FGGTWYWNQYPGAQCDVESYIYMPLLEETGYVPTERYARGPEILKHINLIAKKWELAPK
                     THFQSEVSAADWTADRWTVKTRQGDEFRSRYLVTAIGPFHRPKLPGVPGINSFKGNTFH
                     SSGWDYEASGGSATEKLTKFSDKTIGIIGTGATAVQMLPFVANSAKEVLVFQRTPAPVN
                     VRNNGPTPPDFAKFLEPGWQLRRMDNFNKIYTGEPIDTSIVSEEWLSATLQVLFGTESD
                     KPSDPAELEQLLARTDFQVMERIRRRVDETIKDPVTREQLKPWYATICKRPCFHDEYLE
                     CFNRPNVRLVDTDGKGVDRITEDSVVVDGKEHHVDALVFCTGFEYLSGVDRHGGFTVTG
                     KDGVTLTERWTPGPSTYHGLYVHGFPNFFCLQTAQAGTNPNFMYTATTGSTQIGHVIAE
                     CLKDGVREVQPTKQAEDDWVKMILEGGRGMMHLMRNCTPGYMNNDGNLDEKTARRMFYP
                     GGPTAWRKLLEAWREKGDFEGLQRTY"
     gene            27510..35231
                     /gene="hpm8"
     mRNA            join(27510..27682,27777..28609,28670..28780,28837..29423,
                     29477..30544,30605..32905,32969..33304,33377..35231)
                     /gene="hpm8"
                     /product="reducing polyketide synthase"
     CDS             join(27565..27682,27777..28609,28670..28780,28837..29423,
                     29477..30544,30605..32905,32969..33304,33377..35072)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (11-436). E-value:
                     1.8e-172. Score: 565.9. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (551-862). E-value: 2.8e-96.
                     Score: 314.2. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (931-1120). E-value: 2.2e-22.
                     Score: 72.0. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1640-1953). E-value: 1.7e-118.
                     Score: 387.2. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1976-2156). E-value: 2.4e-51.
                     Score: 166.1. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2265-2339). E-value: 4.1e-12.
                     Score: 38.2. Matches aSDomain:
                     nrpspksdomains_hpm8_PKS_PP.1"
                     /codon_start=1
                     /gene="hpm8"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 252.3; E-value:
                     1.5e-76)"
                     /gene_kind="biosynthetic"
                     /product="reducing polyketide synthase"
                     /protein_id="ACD39767.1"
                     /sec_met_domain="PKS_KS (E-value: 3.2e-173, bitscore:
                     565.9, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5e-97, bitscore: 314.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 2e-08, bitscore: 23.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.3e-19, bitscore:
                     58.0, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.2e-46, bitscore:
                     148.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8e-08, bitscore:
                     22.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTSNPSHVPVAIIGLACRFPGEATSPSKFWDLLKNGRDAYSPN
                     TDRYNADAFYHPKASNRQNVLATKGGHFLKQDPYVFDAAFFNITAAEAISFDPKQRIAM
                     EVVYEALENAGKTLPKVAGTQTACYIGSSMSDYRDAVVRDFGNSPKYHILGTCEEMISN
                     RVSHFLDIHGPSATIHTACSSSLVATHLACQSLQSGESEMAIAGGVGMIITPDGNMHLN
                     NLGFLNPEGHSRSFDENAGGYGRGEGCGILILKRLDRALEDGDSIRAVIRASGVNSDGW
                     TQGVTMPSSQAQSALIKYVYESHGLDYGATQYVEAHGTGTKAGDPAEIGALHRTIGQGA
                     SKSRRLWIGSVKPNIGHLEAAAGVAGIIKGVLSMEHGMIPPNIYFSKPNPAIPLDEWNM
                     AVPTKLTPWPASQTGRRMSVSGFGMGGTNGHVVLEAYKPQGKLTNGHTNGITNGIHKTR
                     HSGKRLFVLSAQDQAGFKRLGNALVEHLDALGPAAATPEFLANLSHTLAVGRSGLAWRS
                     SIIAESAPDLREKLATDPGEGAARSSGSEPRIGFVFTGQGAQWARMGVELLERPVFKAS
                     VIKSAETLKELGCEWDPIVELSKPQAESRLGVPEISQPICTVLQVALVDELKHWGVSPS
                     KVVGHSSGEIGAAYSIGALSHRDAVAAAYFRGKSSNGAKKLGGGMMAVGCSREDADKLL
                     SETKLKGGVATVACVNSPSSVTISGDAAALEELRVILEEKSVFARRLKVDVAYHSAHMN
                     AVFAEYSAAIAHIEPAQAVEGGPIMVSSVTGSEVDSELLGPYYWTRNLISPVLFADAVK
                     ELVTPADGDGQNTVDLLIEIGPHSALGGPVEQILSHNGIKNVAYRSALTRGENAVDCSL
                     KLAGELFLLGVPFELQKANGDSGSRMLTNLPPYPWNHSKSFRADSRLHREHLEQKFPTR
                     SLIGAPVPMMAESEYTWRNFIRLADEPWLRGHTVGTTVLFPGAGIVSIILEAAQQLVDT
                     GKTVRGFRMRDVNLFAAMALPEDLATEVIIHIRPHLISTVGSTAPGGWWEWTVSSCVGT
                     DQLRDNARGLVAIDYEESRSEQINAEDKALVASQVADYHKILSECPEHYAHDKFYQHMT
                     KASWSYGELFQGVENVRPGYGKTIFDIRVIDIGETFSKGQLERPFLINAATLDAVFQSW
                     LGSTYNNGAFEFDKPFVPTSIGELEISVNIPGDGDYLMPGHCRSERYGFNELSADIAIF
                     DKDLKNVFLSVKDFRTSELDMDSGKGDGDAAHVDPADINSEVKWNYALGLLKSEEITEL
                     VTKVASNDKLAELLRLTLHNNPAATVIELVSDESKISGASSAKLSKGLILPSQIRYVVV
                     NPEAADADSFFKFFSLGEDGAPVAAERGPAELLIASSEVTDAAVLERLITLAKPDASIL
                     VAVNNKTTAAALSAKAFRVVTSIQDSKSIALYTSKKAPAADTSKLEAIILKPTTAQPAA
                     QNFASILQKALELQGYSVVSQPWGTDIDVNDAKGKTYISLLELEQPLLDNLSKSDFENL
                     RAVVLNCERLLWVTAGDNPSFGMVDGFARCIMSEIASTKFQVLHLSAATGLKYGSSLAT
                     RILQSDSTDNEYREVDGALQVARIFKSYNENESLRHHLEDTTSVVTLADQEDALRLTIG
                     KPGLLDTLKFVPDERMLPPLQDHEVEIQVKATGLNFRDIMACMGLIPVRSLGQEASGIV
                     LRTGAKATNFKPGDRVCTMNVGTHATKIRADYRVMTKIPDSMTFEEAASVAVVHTTAYY
                     AFITIAKLRKGQSVLIHAAAGGVGQAAIQLAKHLGLITYVTVGTEDKRQLIREQYGIPD
                     EHIFNSRDASFVKGVQRVTNGRGVDCVLNSLSGELLRASWGCLATFGHFIEIGLRDITN
                     NMRLDMRPFRKSTSFTFINTHTLFEEDPAALGDILNESFKLMFAGALTAPSPLNAYPIG
                     QVEEAFRTMQQGKHRGKMVLSFSDDAKAPVLRKAKDSLKLDPDATYLFVGGLGGLGRSL
                     AKEFVASGARNIAFLSRSGDTTAQAKAIVDELAGQGIQVKAYRGDIASEASFLQAMEQC
                     SQDLPPVKGVIQMAMVLRDIVFEKMSYDEWTVPVGPKVQGSWNLHKYFSHERPLDFMVI
                     CSSSSGIYGYPSQAQYAAGNTYQDALAHYRRSQGLNAISVNLGIMRDVGVLAETGTTGN
                     IKLWEEVLGIREPAFHALMKSLINHQQRGSGDYPAQVCTGLGTADIMATHGLARPEYFN
                     DPRFGPLAVTTVATDASADGQGSAVSLASRLSKVSTKDEAAEIITDALVNKTADILQMP
                     PSEVDPGRPLYRYGVDSLVALEVRNWITREMKANMALLEILAAVPIESFAVKIAEKSKL
                     VTV"
     aSDomain        join(27598..27682,27777..28609,28670..28780,28837..29082)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.80E-172"
                     /label="hpm8_PKS_KS.1"
                     /locus_tag="hpm8"
                     /protein_end="436"
                     /protein_start="11"
                     /score="565.9"
                     /tool="antismash"
                     /translation="VAIIGLACRFPGEATSPSKFWDLLKNGRDAYSPNTDRYNADAFYH
                     PKASNRQNVLATKGGHFLKQDPYVFDAAFFNITAAEAISFDPKQRIAMEVVYEALENAG
                     KTLPKVAGTQTACYIGSSMSDYRDAVVRDFGNSPKYHILGTCEEMISNRVSHFLDIHGP
                     SATIHTACSSSLVATHLACQSLQSGESEMAIAGGVGMIITPDGNMHLNNLGFLNPEGHS
                     RSFDENAGGYGRGEGCGILILKRLDRALEDGDSIRAVIRASGVNSDGWTQGVTMPSSQA
                     QSALIKYVYESHGLDYGATQYVEAHGTGTKAGDPAEIGALHRTIGQGASKSRRLWIGSV
                     KPNIGHLEAAAGVAGIIKGVLSMEHGMIPPNIYFSKPNPAIPLDEWNMAVPTKLTPWPA
                     SQTGRRMSVSGFGMGGTNGHVVLEAY"
     aSModule        27598..35039
                     /complete
                     /domains="nrpspksdomains_hpm8_PKS_KS.1"
                     /domains="nrpspksdomains_hpm8_PKS_AT.1"
                     /domains="nrpspksdomains_hpm8_PKS_DH.1"
                     /domains="nrpspksdomains_hpm8_PKS_ER.1"
                     /domains="nrpspksdomains_hpm8_PKS_KR.1"
                     /domains="nrpspksdomains_hpm8_PKS_PP.1"
                     /iterative
                     /locus_tags="hpm8"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       28013..28033
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0001"
                     /evalue="1.10E+01"
                     /label="PKSI-KR_m3"
                     /locus_tag="hpm8"
                     /protein_end="125"
                     /protein_start="118"
                     /score="0.5"
                     /tool="antismash"
                     /translation="PKVAGTQ"
     CDS_motif       28175..28222
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0002"
                     /evalue="9.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="hpm8"
                     /protein_end="188"
                     /protein_start="172"
                     /score="17.7"
                     /tool="antismash"
                     /translation="GPSATIHTACSSSLVA"
     CDS_motif       28364..28402
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0003"
                     /evalue="1.80E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="hpm8"
                     /protein_end="248"
                     /protein_start="235"
                     /score="8.6"
                     /tool="antismash"
                     /translation="FDENAGGYGRGEG"
     CDS_motif       join(28595..28609,28670..28702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0004"
                     /evalue="3.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="hpm8"
                     /protein_end="328"
                     /protein_start="312"
                     /score="12.9"
                     /tool="antismash"
                     /translation="YVEAHGTGTKAGDPAE"
     CDS_motif       join(28763..28780,28837..28863)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0005"
                     /evalue="8.80E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="hpm8"
                     /protein_end="363"
                     /protein_start="348"
                     /score="11.8"
                     /tool="antismash"
                     /translation="GSVKPNIGHLEAAAG"
     CDS_motif       29478..29531
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0006"
                     /evalue="3.30E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="hpm8"
                     /protein_end="568"
                     /protein_start="550"
                     /score="19.4"
                     /tool="antismash"
                     /translation="FVFTGQGAQWARMGVELL"
     aSDomain        29481..30413
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_AT.1"
                     /evalue="2.80E-96"
                     /label="hpm8_PKS_AT.1"
                     /locus_tag="hpm8"
                     /protein_end="862"
                     /protein_start="551"
                     /score="314.2"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWARMGVELLERPVFKASVIKSAETLKELGCEWDPIVE
                     LSKPQAESRLGVPEISQPICTVLQVALVDELKHWGVSPSKVVGHSSGEIGAAYSIGALS
                     HRDAVAAAYFRGKSSNGAKKLGGGMMAVGCSREDADKLLSETKLKGGVATVACVNSPSS
                     VTISGDAAALEELRVILEEKSVFARRLKVDVAYHSAHMNAVFAEYSAAIAHIEPAQAVE
                     GGPIMVSSVTGSEVDSELLGPYYWTRNLISPVLFADAVKELVTPADGDGQNTVDLLIEI
                     GPHSALGGPVEQILSHNGIKNVAYRSALTR"
     CDS_motif       29718..29810
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0007"
                     /evalue="4.10E-09"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="hpm8"
                     /protein_end="661"
                     /protein_start="630"
                     /score="28.9"
                     /tool="antismash"
                     /translation="GVSPSKVVGHSSGEIGAAYSIGALSHRDAVA"
     aSDomain        30681..31247
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_DH.1"
                     /evalue="2.20E-22"
                     /label="hpm8_PKS_DH.1"
                     /locus_tag="hpm8"
                     /protein_end="1120"
                     /protein_start="931"
                     /score="72.0"
                     /tool="antismash"
                     /translation="LIGAPVPMMAESEYTWRNFIRLADEPWLRGHTVGTTVLFPGAGIV
                     SIILEAAQQLVDTGKTVRGFRMRDVNLFAAMALPEDLATEVIIHIRPHLISTVGSTAPG
                     GWWEWTVSSCVGTDQLRDNARGLVAIDYEESRSEQINAEDKALVASQVADYHKILSECP
                     EHYAHDKFYQHMTKASWSYGELFQGV"
     CDS_motif       30759..30836
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0008"
                     /evalue="1.00E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="hpm8"
                     /protein_end="983"
                     /protein_start="957"
                     /score="27.7"
                     /tool="antismash"
                     /translation="WLRGHTVGTTVLFPGAGIVSIILEAA"
     aSDomain        join(32808..32905,32969..33304,33377..33881)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_ER.1"
                     /evalue="1.70E-118"
                     /label="hpm8_PKS_ER.1"
                     /locus_tag="hpm8"
                     /protein_end="1953"
                     /protein_start="1640"
                     /score="387.2"
                     /tool="antismash"
                     /translation="GLLDTLKFVPDERMLPPLQDHEVEIQVKATGLNFRDIMACMGLIP
                     VRSLGQEASGIVLRTGAKATNFKPGDRVCTMNVGTHATKIRADYRVMTKIPDSMTFEEA
                     ASVAVVHTTAYYAFITIAKLRKGQSVLIHAAAGGVGQAAIQLAKHLGLITYVTVGTEDK
                     RQLIREQYGIPDEHIFNSRDASFVKGVQRVTNGRGVDCVLNSLSGELLRASWGCLATFG
                     HFIEIGLRDITNNMRLDMRPFRKSTSFTFINTHTLFEEDPAALGDILNESFKLMFAGAL
                     TAPSPLNAYPIGQVEEAFRTMQQGKHRGKMVL"
     CDS_motif       join(32898..32905,32969..32996)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0009"
                     /evalue="6.90E-04"
                     /label="PKSI-ER_m1"
                     /locus_tag="hpm8"
                     /protein_end="1682"
                     /protein_start="1670"
                     /score="12.6"
                     /tool="antismash"
                     /translation="GLNFRDIMACMG"
     CDS_motif       33180..33224
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0010"
                     /evalue="1.30E-01"
                     /label="PKSI-ER_m4"
                     /locus_tag="hpm8"
                     /protein_end="1758"
                     /protein_start="1743"
                     /score="6.2"
                     /tool="antismash"
                     /translation="AASVAVVHTTAYYAF"
     CDS_motif       join(33249..33304,33377..33383)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0011"
                     /evalue="2.00E-10"
                     /label="PKSI-ER_m5"
                     /locus_tag="hpm8"
                     /protein_end="1787"
                     /protein_start="1766"
                     /score="32.8"
                     /tool="antismash"
                     /translation="GQSVLIHAAAGGVGQAAIQLA"
     CDS_motif       33522..33560
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0012"
                     /evalue="1.10E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="hpm8"
                     /protein_end="1846"
                     /protein_start="1833"
                     /score="14.7"
                     /tool="antismash"
                     /translation="TNGRGVDCVLNSL"
     CDS_motif       33834..33881
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0013"
                     /evalue="4.20E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="hpm8"
                     /protein_end="1953"
                     /protein_start="1937"
                     /score="19.6"
                     /tool="antismash"
                     /translation="AFRTMQQGKHRGKMVL"
     aSDomain        33951..34490
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_KR.1"
                     /evalue="2.40E-51"
                     /label="hpm8_PKS_KR.1"
                     /locus_tag="hpm8"
                     /protein_end="2156"
                     /protein_start="1976"
                     /score="166.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="ATYLFVGGLGGLGRSLAKEFVASGARNIAFLSRSGDTTAQAKAIV
                     DELAGQGIQVKAYRGDIASEASFLQAMEQCSQDLPPVKGVIQMAMVLRDIVFEKMSYDE
                     WTVPVGPKVQGSWNLHKYFSHERPLDFMVICSSSSGIYGYPSQAQYAAGNTYQDALAHY
                     RRSQGLNAISVNLGIMR"
     CDS_motif       33954..34052
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0014"
                     /evalue="4.20E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="hpm8"
                     /protein_end="2010"
                     /protein_start="1977"
                     /score="48.3"
                     /tool="antismash"
                     /translation="TYLFVGGLGGLGRSLAKEFVASGARNIAFLSRS"
     CDS_motif       34281..34310
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0015"
                     /evalue="9.40E-04"
                     /label="PKSI-KR_m3"
                     /locus_tag="hpm8"
                     /protein_end="2096"
                     /protein_start="2086"
                     /score="12.5"
                     /tool="antismash"
                     /translation="PKVQGSWNLH"
     CDS_motif       34335..34445
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hpm8_0016"
                     /evalue="2.90E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="hpm8"
                     /protein_end="2141"
                     /protein_start="2104"
                     /score="58.4"
                     /tool="antismash"
                     /translation="LDFMVICSSSSGIYGYPSQAQYAAGNTYQDALAHYRR"
     aSDomain        34818..35039
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hpm8_PKS_PP.1"
                     /evalue="4.10E-12"
                     /label="hpm8_PKS_PP.1"
                     /locus_tag="hpm8"
                     /protein_end="2339"
                     /protein_start="2265"
                     /score="38.2"
                     /tool="antismash"
                     /translation="DEAAEIITDALVNKTADILQMPPSEVDPGRPLYRYGVDSLVALEV
                     RNWITREMKANMALLEILAAVPIESFAVK"
     gene            <36050..>38015
                     /gene="hpm9"
     mRNA            join(<36050..36238,36318..>38015)
                     /gene="hpm9"
                     /product="alcohol oxidase"
     CDS             join(36050..36238,36318..38015)
                     /codon_start=1
                     /gene="hpm9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 358;
                     E-value: 1.9e-108)"
                     /gene_kind="biosynthetic-additional"
                     /product="alcohol oxidase"
                     /protein_id="ACD39768.1"
                     /transl_table=11
                     /translation="MFCIIRAQLLLLLHLLVLALLLVGTVCNAHPQHGHPSELEPLALK
                     RGGSPRDDGNTLAPRCRCIPGEACWPSTQIWDSFNRTIGGSLIKTAPLAESCYPGPKKN
                     TRKCAVVSRKWTDQDFQTDSPVGRTYPYNITCAPVNYFAGQRPTTCSLGQLPVYAIDAR
                     TRQSVAQGLRFAKDNNLRVTVVSTGHDLLGRADGYGSLEIWLRHHRNEIRFERQYMATD
                     GCRESGWTGSAIDIDGAYQWRDVHIKARANNVIVVGGGSVSPGAIGGWPSGGGHGPASR
                     NYGLGADQILEAEVMLADGSVVLANHCQHTDLFRALRGGGPGFGVVLKTKIKAYPNVAS
                     VSVHHLTITPIRQTPNNSDLLDAVAVLMQAYPKLSDDGYAGYAFWLRNCKSFFIGSAKS
                     GYRHGIWMIGKTTEEAEHSFAPVREALDKFKSKLTISESYMTYNDYWSFYTSESGLYES
                     VGTTSVLTSRLIDRPAVEDYNRVREAVEVIGGKPEDYATNVMMLVSNGQVFADAADKSS
                     GLNPAWRVSPYVVISSRGIPMVVDQASRKEVADDITYVKGAALQKLAPNTGGYMNEGDR
                     NDPNYIKNFFGTIYPTHLATKKKYDPWGLFYCPTCVGAELFEETSRGELCRR"
     mRNA            complement(<38330..>39256)
                     /product="oxidoreductase"
     CDS             complement(38330..39256)
                     /codon_start=1
                     /note="orf10"
                     /product="oxidoreductase"
                     /protein_id="ACD39769.1"
                     /transl_table=11
                     /translation="MRLLRVLLMNYKSFLGKDVPALASYSEETGMIRLQVNPSVAANQQ
                     TPGTYYYMYFPGWRVWECHPFTLAGRSSEIEDVTSSSELSDRDTDGEKRVQSPRITEFS
                     VTKSEQYMTFMIKPRDGMTKRLRDSLRGEGSSGQRRVRVYIEGPYGTPARFNNFDNVLF
                     ITGGSGITTVLPYLRMFFEDGYNGGRIPNTKLAWMVRHEGFVRDVLANDLRRVESAPAA
                     ATKLAMEFYITNGGTIDEKYTQDTRFRRERPDVDALVHNFAESHPGRTAIFVCGPAEMA
                     DKTRLAVIKQVKSGYNDIEVFEEMFNW"
ORIGIN
        1 gatcaatttc ctaccctaca tcgcgatgtt aggatattgg cgccagtagc ttcgacgtat
       61 gatgtcggag acacatataa ctagatgacg gcgagtttgt aacaaaaaat gagcgaaggg
      121 tttagatgga tggcgaattt gcatgacttt gcagggctgg ttgttcgatt agcgaaagaa
      181 gtactcatcc tggcattatc atattctttt ctaaagagtc gattactcaa gaatagctgt
      241 actaggcgtt agaactgtac tcttagaggt atcttgaatt tcatcttatc atggggcata
      301 gttgtagact acggcttgag tcccatggta attgttaggt atatgttcag gaaatcatta
      361 gaatccatac tgtggatgct gaaagctgga gagagaaggc tggaaagact agatgcgaac
      421 caagcccacc ttatgtcgac ctacataaat gtctatcggc ctgtgatttt attcccgaca
      481 atagcggaat ctatagcgca cttccagtgc atttagagga tcgcatcata tccccgaaga
      541 ataagcgaga aggtttagag agatatcaca tcaatactag accgttgaag agcgatgaac
      601 aatttgagag cttgatcagc atttctgctc tttacacaaa tttacacacg acttgatcag
      661 aaaaccccgg cggagaagat aaatagtttg tctcaggtgc aaatatcttc cgatattagc
      721 cccacatgat gaacgaccga tatccatctc agccaacccc tccttggact tctcaatgac
      781 acctcaaatt ctcgaacgtg acggtgacat tatcccagac aattccaaaa tttcttaata
      841 ccccgagcaa ctctccttat tctgtacttg tactctgcgc cccttacaca agtgacaagt
      901 attcaggatg gcgagggctc ttattcgagc tcacaccaat aaatctcaac gattatcacg
      961 agacggtaat cggaacctca actggtagcc cacattggaa gcacaaggac tccgtacgca
     1021 gcgagtgtaa gccaaagcac tacacagtcg aacacttggg ctcggtcgtt tattcacgaa
     1081 acttgcctgc cgagaggctg tcaccccacg gtttttcact gtctgaaact tggtttcctc
     1141 gtcaagctgc tctaccctgt caactctgtt tactgtttca accttagtgg tacaatgcca
     1201 gctagcttgt tggttcgcgc tgagggtaac aaagtagtat gacatgcatt cggagcatac
     1261 ggggtagagt cggtacagtg gcttttgggg gaaaaggaga atcttctcct gatacgcccc
     1321 caggggggcc tctctgggct ttctgccatt tgttcctgcg agtttccctc gcttttgact
     1381 gagtttgaac agtccttaga tcatagggaa gatcacgatc tacaagtatg agacagaact
     1441 tagcggttgc tcaggttcag gaggcacaaa ctacgctgta gagttcttga tcatgaacgg
     1501 ccactacaga gtactacggc ttgggtatga gagggttcta agcagcggtg gtcgccattg
     1561 tgcaatcttg cgaaagtaca agtattgcga cgctattgat aaccctggaa gattgttcaa
     1621 caaactcaat actccgtaca tacttggtcg gatacgccac gccaccctct ggcgacaggc
     1681 aaatttcagc tacgattgac cggggaaata ttgcatctcc cgcgtgagcc ccggcttcag
     1741 ccatgtcgac cgacaccctt gaaaggctcc ccaagtttgt gacagtgcaa cggccaagct
     1801 tgttctttgc ggagtttggg aaacattgaa tgacaattgg ctaaagaaga gtctgtacgc
     1861 cgtacggatc tcttggaaat cttggatggt atggtattga agactaactc ggcagtgcca
     1921 tgtttatagg ttggttgtag tctgtgagtt gggactcact gtcactgcta ctcaggacat
     1981 tagatggcag tcgagactac ctacttttac atcattttag gaccttggag tcaaggacac
     2041 cattaggggg attttctccc agccaaagta ttccaccatg tcatccaccc aattatcgca
     2101 gctcttgtca agcttaatat caaagttcca gaagagtctc gccaagatca gtcgcagctc
     2161 gacgtaggtc agattcatgc cgatgcagtt acgggggccc accgcgaagg gttgtgaagc
     2221 atccttcttg tcattatcga aacggggatc atcgagccag cgctcggggt ggaattcgtt
     2281 ggcatgcgtg aaaaagtccg ggcagcgagc catgctccaa tgccaaatgc ctgtgtcacc
     2341 agttagctat ttgtttggcc ctgaagataa agatggatgg tccacattgg agtttgacat
     2401 accgacactc gtctgtgaga tagaggtatt agcgaccgat caaatcatca atgaagggag
     2461 aagaaaaact tacgcctgca ggaataaatt cgccagcaat ggtagcgcct ccacggggaa
     2521 cctgtcgcgg tgaagcaccc gcgaaaggag ggaacatgcg gagtgactca gtgatgacgg
     2581 cgttgagata cttgagatgc cccgttcctg tcaatgtgat ttcgtcttca ctggagaagg
     2641 ctgatcgaac ttcttcaatg accttggcca tggcctccgg gttcttggtt aggtagtatg
     2701 tggtgccact gagagcactg gagatggtct ccgcaccccc aaggatgaga gcagtgcagt
     2761 tggatgtgat ttcggtatca gaaagcttgg cgcccttttc atcgtttcca agcatagcgg
     2821 tcatatagtc agggcggctg gcgccaagag cacgacgttt ggcgattttg gcatcagtga
     2881 gttgctggtt ctctttgagt cttctaccga atcccttggg cgtgatgaat agtaggacag
     2941 gcaaaaaggc tctgttgatt ctcttcaagc agttggcgag aataacgaat ctggtggtct
     3001 cgaagatcaa agatgcccag gggtgatggc caccactatc gagagatcct aaagccgtgg
     3061 tcaactttac gcgaacatgt caacgaacat cacgagaaag attcttaccg aaagactcgc
     3121 caaatgtcaa atcacctaga agcggagagt cagcatacat ctcatcttgg ttgttcgact
     3181 gccttcatgc actatccagt aaacacttac cgatgatatc aaaagcagtg aaactgtacc
     3241 atgtttggat atcaatgagc ttctggccac cctcacagcg ctttttaagc tcagaaagaa
     3301 gcagatcaac gtaacccttc agcaaaggtt cttgcttctg gaaggtagcg gcggagaatc
     3361 cgcgagatag gatccttcgc atgcgcgagt ggtcctcacg ggttgttact ccgagtaggt
     3421 tgtccttgaa agcttcattg aagatgggct ccttggtcat ctcaggctgg cctggcttgc
     3481 ggtggccgcc aatatcattc caagcggaca cggactggaa agccagctca tcaggcgcaa
     3541 ttcgcaagat gggaccatat ttcttgtgta aatcgaggat gatatcgtgg gatttgccgc
     3601 tgatgatggc gagggagacg ccccagcgag ttacagccca gaatttaggg cccggaaact
     3661 tgctgagagg atgaaagtag agcaggtaga tgggatttac gacgaacacc catgcgaaga
     3721 actaatattc aaagtcagtt ggcaattcta gttcgtgaga gggagtcaat acatacagca
     3781 ccaacgataa caaaggctgt gtctcggttg gcgaggtgcc ccaaatctac ttggggtaac
     3841 actgccataa tgggcaaaaa acaacgaaga gaaaaaaatt ccttaacgaa gggttgagct
     3901 ttcggaaaag gcgtattctt tatgaggaga aagaagagaa agaggaagag ggaaaagaga
     3961 aaaaccaaga cgttttgtac tacgagttca tgcagcagag ctcaatgctt gttacgtaca
     4021 tgtatgttgc cagccgtgat gaatccttca cttatgccgc ttacatgacc atgtgggctc
     4081 ggtgctctcc ctacagagaa atcagccacg ctcttctgtt cctggagaga gccttgagct
     4141 cacaagcaat caactccaat gaagggtatc tcacgtatca catcaaaaaa gcacaacaga
     4201 ttgggtagca tgcatgccta cgagcggggt aaccgaatcc tattccatgt gggcgggggg
     4261 ccggaaatgc atcgattgta tgaacatgga tggatgatgt gatgcaacat acaacataca
     4321 gcatactctt atcttgctat ttgggggggt tcagccaagg ggctgcttga ctcgacactg
     4381 aatataatgg ggcggagctc cggaggatgt ggaactacaa caccagcctg gcttagacct
     4441 gtcatccaat cgactgattt gatgtaatgt cggttgctgt tgtctgttgg gtgccggtgt
     4501 aagtaggctt ggtagggagt aggtgtgcct gggccctggc caaaggatgg aaggaaatgc
     4561 cggatccctc gagagatcgg ttggtcgatc gacctcggtg ttactccttc tcggagccat
     4621 gacggagtgc tatggcaagt cggagtatga tgtgtcgatt cccctgtgtt ggacccaaat
     4681 ggacccagat ggagccaact tcatgttggt tgagggagag tgtattgcgg agctttggcc
     4741 accacgtggt ttatataacc tcgctcgcaa tcactctata atcacgcatc tcctcattct
     4801 tcattcattg caaagtcgcc aaagtaaaat tcatatagtt gttcttcgat ttcatacgtc
     4861 aaaccgccag gatggttatc aagctgtacg gctctgccat gtccacggcc cgtgtgctgg
     4921 tcacacttct tgaaaaggag ctcccctacg agcacatcct cgttgatatc tccaaaggag
     4981 accagaataa ggaagaatac ctgaagcttc agccctttgg caaggtgccc gtgttggatg
     5041 acaatgggtt catcatgtac gagagccgag ctatctgtcg gtatcttgcc cggtgagttt
     5101 cttacaattg cacaccacaa aatggatcat tcatggagat attgctaatg agaaggatag
     5161 caagtacgat tcaggtacca aattgatccc cgatgtggat gatcatgagg cgtacggccg
     5221 cttcgagcaa ggctgttcta ttgagtacag ctactttgct gccgcagccg aaaccctggg
     5281 aactgagctg gtcatcaaaa agtaggtcca aaccaagtct tcaagttatg agagctgtct
     5341 gggaaatggc agaatcaaaa ttgctgacac aaattggccc atagatacaa aggactgggt
     5401 gagccggaca tgaccagagt cgctcaggcg gaggccgact tcgacaaagt cttcttcgag
     5461 tacgacaaga tcctggccaa gcaaaagtac ctgacgggcg acgagatctc actggtggac
     5521 ctgttccact tgcccaatgc ctctgccttg aaggcattcg gataccaggg aacctttgag
     5581 aagtacccca acgtgaacag gtggttctcc ggcttgcagg cgagggagac gtggatcaag
     5641 gccacagcgg aggccagata agtggcttga agctgaaaga ttgtacatga agtttatcct
     5701 agattcgtga tcctacgtaa taaatgaaca gtgatcaaaa tagctcattt tgtgacagat
     5761 gatgagtcgg tcaggttttg acatgcatac gtacatacac acctacatgg tgatgactgc
     5821 atgccacaaa gcccgggcta aattaagagt tcacgatttc tcaatggtcg acagcaagtt
     5881 cacagaatgg aaagaaatgg aagaagtctg accagtgaga gactcaagat agcttcagcc
     5941 tcatgcggtg ggtgagaaca atttcaattt gcaccacatt tcgaacccct atctttgacg
     6001 acatccctag aacatcaatc ttcacgttcc aacagtaaat tgatatgaaa agtacgctat
     6061 catgaattat catcgcagct agttggcatt ctagtccgta aatcttacaa atcgtctccc
     6121 aaaaagatac tcatgcagtt caaatgaagt ctaatttgcc tcgctgaaat atttgaacga
     6181 ctcctccatc gccgcctgaa gcaagtgcac atgccccggc atcggcatat ccaagtggtc
     6241 cgaatcgata gacaggcaca gagtctcgcc aaggaacttg tcccatccgt tgggtcccaa
     6301 gtccgcagcg gacttgtgcg gaaggcccca cgccacggca cccagcttgg ggtcctccat
     6361 gaaccctggg tacgactcgg tggggatgcc cttgtcggcc aggaacttca tcaccttctc
     6421 gtcgcgagag caacggtcga ccatgccctt tttagcccag atgatagctg ttcgcttggg
     6481 tcgttgagcg ggagttatgg gaggagggtg gtaggctgcg acgcaggcga agacggcctt
     6541 gagatgctgc tgggtgttac ttgaggcgtt ccagagctta tcttgggaag cgatggtctc
     6601 gtagaccttc cagccgacct cgattgtgtc ctcaacaccc aaaggacggg gagaacacat
     6661 atcgatgagg agaagactgg agacgacgcg accggcggca gcgagttggc gagacacctc
     6721 atagctgagc atagctccgc cagagaatcc tcccaagtca aagggaccct caggctggca
     6781 cttaatcaac gcctcaaaga tgatctttgc gacgccttca atgcccacct gggtggtcag
     6841 cctgctgggg caacggagga aaggcgaatc aatgccataa accggtctct tgtccttgaa
     6901 gggagccagg tggatatacg tagcaatgct accagctcca tcggcgatca agtagaaagg
     6961 ctgctttcca ctcgaagatc gaccctggat caaggtgatt ctggcactgg ggaggggaga
     7021 ggaatcctcg acaaccgcgg acggaacgat caccagctcc tcagacttct ctgaagccgg
     7081 agcaggctcc ttcttctcag aaggcgctcg actcgagctg cgcgtagact ctggagtggc
     7141 atcgacgatg gagaactcgg aaaaggtctt gctgggaggt gtagatgtag aggagcgcgc
     7201 aaattcgttt cgcagatctc caatggtggg ataatctacg acaaaagagg ggaggagaac
     7261 atcgaggccg gttctgctgc tgacgccggc agcgatctca atacccatga tggaatcaac
     7321 gcctgtgtag agattgttag cttttgtttt gttcaaggtg gaaggggggt ttaagggcat
     7381 tgtcaacgta ccaagttcag ccagttccat gtcatcagtg aagtcagaga cctgagtgcc
     7441 agtctccttg gcgatgcttt caagaatagt gtggaacaat tcactctccg acgaagagat
     7501 cttcttcacc tctgtcttca caggctcagg cgccttggga gccgcctcga cagcagcttt
     7561 cagggccggt tttgactctg cgggcacaag cactggcgcc ttctggtggg aaacttgctt
     7621 cacaggcggt gatgcctttc caagaagtct gtccagaaca ttgttgctga cctcatggaa
     7681 tgagagtccc gagcactgca tcaccatctt ctccgagtcg aagacgaaca agtcacagct
     7741 gactgtgtct tcttcctcat gcaaaacgcg agcataggtg tagtaagtgc gtccagcctc
     7801 gagatcagcg gtctgctcga cgctctcaag actctgcatc atgaaggtcg tctgagaagc
     7861 agtcttgcgg gcagggttgg agttcacgag gaaaccggca agatgaacta cgctctcacc
     7921 ccagtaaggg gacgcaaaga actgagttcc agccgggttc ttctgaagca ccacctccgc
     7981 agcagcttcg tcaaactcat ttgagatgaa ggcctccttg acagacttga aggtagggtc
     8041 ataatcaact gtgctagcga agagagtgta gaggatactg gggagcatgc ggtgaccatt
     8101 tccgctcttg acattcttga tcaactcgtt catacgagcc ttgacgaagt atgagcttct
     8161 gttccagcta gtttgaagag tctgggcatc acaaatggtg atctcgcagc taccaagatc
     8221 gtatgatgca tgagaggaag aagccttcca tgaaacctgc aaggtatcgc tggaggcctt
     8281 gtctgcaaca accgtggtga gaagctcgcc atcggtgcct acaagagact ttgtgagcgg
     8341 gcgcttgaga gacaggttgt tgattgtaag tcttgtttcc acggtatcct ttcggccact
     8401 gtacttcagt gcgtacttgg agacggcaag gcctgcctcg cagaagacac ttccggggca
     8461 gatggacaca tcgcgcatgc gatgaccgtc gaccaaggcc atgaagccag gatcggagat
     8521 agcagctcgg gcagagacat ggaggctggg tgatgatgat tcttcaacaa tctgttgagc
     8581 acatgtagaa atcctctgtg tttcgaacga gggagcggga gccaaagctc gagcagcctt
     8641 gttggcctca gagtagacaa tccagaagtc cttgaggtcc catgcatagg cgggcaactt
     8701 cacgagcttc aagccgccct tgaatggagc atgcaccgcc aaccagtcaa ctgcgacacc
     8761 atccttgtac gcgccggcga ggcacttggc aatggatgcc caggggttgg tatttgcctc
     8821 caaagtggac aagattttgc ccggcgaggg tgagagagtc gcccggacaa aggagttgca
     8881 gatttggctg ggtccgatct ccagccagag agggtcagca aacttctcct tcaaggcgcc
     8941 aagagcaccg acgaagtcga cagcttggcg ggtttgctga ccgaggtagg aagcgttgaa
     9001 gacccctgaa gactccacaa tcgaagcgag cagggttgaa gcaactggaa tctttggtgg
     9061 cgagtaggtt acaccacccg caagaacgat gtaatcctcg agcatgggat ccatctggaa
     9121 ggagtgaaat ccatagggca cagacagagc cctggctcgt gatgccgtga aggatgactg
     9181 gagctcagaa atctcatcag tgctgccgct gataaccgtg gcattggggc tattcttgca
     9241 tgcaatctcg aaggatgact gcgggcgctg gtcgatgagc tcgcggatgg aggcagcaga
     9301 gcttgatact gccaacatag cgcaggtgtc ggcttcgcag cgctccagca ggagacgggc
     9361 ccgattgccg acgaggtaga gcagatcagc tagagatagg acccctgcga cctggagagc
     9421 cacatactcg cccagggagt gacccatgac tgctgacggc tggataccag acgccttcca
     9481 gaatgcggcg agggcgatct ccagcgtgac aacagcgagc tgtgtctgca tggtgtcctt
     9541 ggtggttatg tcaacatctt tgttggtgat gatatccacg tacgggggga acccgtgctc
     9601 ctcagagatg ctggcacaga ggttgacttc ctcgcggaaa gcagggcatg tcttgtacaa
     9661 ctcggcaccc atgccggcgt agtgagagcc ctgtcccgtg aatacgaaga caacgggcga
     9721 gccccgagac gcagttgcat ctgccgtgtc tgcctcaagc ttggaaatga gctcctccgt
     9781 tgtggaggca ctgcaagaga atctgagggg gtggtgcatt ctgcgggcgg tggttgtgta
     9841 tgcaacatct tcgagtttag catctttgtt cttgcgtagc cacttcagga ggttacgctt
     9901 attcgcgtga tatgaggatt gtgttttggc agaggaaacg atgacatggc ttggcctggg
     9961 gtccgcattt tccttgacgg tggaggggaa gtcttccaga atgagagagg cgttgccacc
    10021 ctttgaaaat tattagcatt agaaatactc cagcccgtag atatgacttg tgagaacacg
    10081 tactgctgcg tcaaagttat taaggaggat gcgtcgtggc cgctcgccga tagccttgaa
    10141 ctccttcggc tcggagggga tatgaatgtt aagctcagaa agactcggat actttgggtt
    10201 gagagtatgg ggcattcgag cctgaggggg cataatatct ttctgcaaac aatatgatga
    10261 gtattcctgt gattaatcat ggtgttggga tcaacatacc tggaacatct gtatgcattt
    10321 gagcagggag gccatgccag cagactgaat ggtaagtcag catttcatta tgcagtgaat
    10381 cacaaggact tctttcttac agcttcagca tgcccgacgt tcgctttgat tccaccaaca
    10441 gttagggggt tattcgcctt cctcttcctg aagacattgg taacagcact catctcggcc
    10501 ggatcgccaa tctgagttcc agtgccgtgc atctcaacat atgagatctc atcaggagag
    10561 actctggcgc tgtgcataat cttgtgaaac agtctctcct gggcaccggc atccgacgtg
    10621 gtgatggatg aagagttgcc ggagtggttt ctgcctgaac cagccacgac agccaagatg
    10681 ttgtcgtttt gctcgacagc atcttcgaga cgcttcagca caactgagcc gacaaagtct
    10741 gctcggcagt aaccatcagc atcatcgcag taggttttgc agtttccagt gtcggacaag
    10801 acaccagact tgctaagact tgtccaggag tgaggatacc cgacgacgtt ggcagcaccc
    10861 acaacagcca tgtccacatc tttggataga agactcacgc aggccaggtg aatagcagag
    10921 gaggtggagg cacatgcaga atcgagcgag tatgttgggc cctcccactt gaagtggaag
    10981 gcgatgcgac cagcgccgaa ggctctttgc gccccctgca gggtgtaggc atcacaaccc
    11041 agggtataat ggctcaccat atgccaatca tcgttggact ggccatagaa cgccgcgatc
    11101 ctattaggat caacgtccct agtctggcca tcagagtatc ctgccgtctc aagagcttca
    11161 taagtgctca tcatgaactg cctgtgaccg gggtccatca acagcgcctc acgaggcgac
    11221 acgtggaaga agcgggagtc aaagtttcca ggcttgttca tgaagcagcc gtattttgtg
    11281 gtggtggtgc aaccctcccc gtgctcggta cagtagaact cattgatgtc gaagcgatct
    11341 ttgggaatct cttcacaacg atcctgcttc gccataatga cgtcccagaa ctcatcaaca
    11401 ttctcgcagc caggaccacg gccagccata ccgacaatgg cgatgcggcc cggggggagt
    11461 ttcttcggct gtaactgctc aagagtctta tcggtctgga aaatagcctt gctgccagca
    11521 gctttgagcg aactcgccaa gtagggggtg tggctgctag gtccgatgac tcggacgtcg
    11581 acatgacgag ggccgaggtg agtgttgagt tgcgcaatca ccttggtaat gtccaaaggc
    11641 ttggacaaaa cttgagtgac gattgctctt agcatttctc cccagttctg gtaggatgcc
    11701 acaggatcat ccattcccca gactttgaag tctggcacaa tggggtgact aagaagctca
    11761 gcactcccga caatgaagtc gaggtcagcc tctgtgactg tgactgtgtg ctgaagggcg
    11821 tggatgctca attcattctt ggggaggttg cgcacagcgg gacactggtg gatgaatagg
    11881 tccaagactg agggtggccc aataacggtg ctccatcggt ctcctgttac gccaacctta
    11941 gctctcttga tggcaggaat cccctgttgc actttcgtta ggctaatttt tgtacgattt
    12001 taggagatgt tcctggtcta cttaccatgc tggattggaa ctgctcaagc actttgctca
    12061 gttcctctgg tgtaattccc agcactgccc agccccaaac gccaggtcgg tcctccatag
    12121 ctcttgatcg taccgaagta aaacggcata atctgacaaa tattctcgca gcctcaatga
    12181 ctgcgtcata tagagactcg aagtctgtgg atatcgccag tgctgcgagg ttggtgagtc
    12241 ctccagagat accgagtgct tcaggcttgg agccattgag gtccacaagc tgtgattctt
    12301 tcttcaccca tcttgattca cggttagcaa cgtcaagcca gccacggctt acaagcagaa
    12361 cttactgtaa tagcatgcct cctctcgcgg catgtagcaa gacagcacgc accataccaa
    12421 tctcgtcggt gccatggcgg tatctatccg ccaagtcgag tagtgtagag tattcaccaa
    12481 cactgtcttg taacgcacga tccatgcccc gggactcttc cttgaagacc tttacaaggt
    12541 cgtcgagaaa cgtctgtagc catggtatcg tagcggcttg tctgtatagc tgatcgaggg
    12601 aatcaaccca ggagtctgtc tgatctccaa agtagaggat agtctgtggt acagtcacca
    12661 tgtttgctaa aagacaaaga gacgcaacaa ggtggtttga aagttcaaag taacatgaaa
    12721 gaacgggata aagagggaag aaaagagcaa tatagagtcg gagttacgaa atagcgtatg
    12781 caagttgtag gctttaagcg atgaggtatg atagaagtcc aggagataaa gccttgtaat
    12841 cggatatgat accggcccag ggagcaaaca ggaagataag caagtcagcc cgcaggcagg
    12901 tctttctata tattaataca tgcgtctctt gccgatccct tgctacggaa agcatggaaa
    12961 gggcttccgg cccggcatca gtcagatacc tcacatccaa ttacagatag ctcaacaacc
    13021 catatgccta gatccagaag gagtaaaccg atggagattg aaggccaagc taggattggc
    13081 cgtgtcgctc agtgcctacc gagaccgtga agccacccgc tgtactgcaa atatatgaac
    13141 ggctaactat attaatgcgc ttcataagca tggaagagtg gcgccaggtg caagactcag
    13201 ctgcaaaacg atcctgtatg gaaagataag gatctagcgc ccgacttgta gggcagacag
    13261 gaccagggct caccttgcac agtcttttta tttcgcgacc tctatggcgc tcaatgcaac
    13321 gtcgggtgga gggcagcttg ggcagatcgg agcttcggcc gtggagtcgt caacacgggc
    13381 actacctgtt ttgagatggg ctcgaatggg ttcaacggca cacaccctcc acccttcatg
    13441 acttcattcc cctaagcact agcccatgat gatgcacgtc ctgaatcccg cgacgatacg
    13501 tgtagggatc tcacggctat accctggtct ggatagagaa agagccggca cccgtcttgc
    13561 agtcagttgt ttacctggtt gcagacatgg ccattcacag ccgagcgagg ggcggcaaca
    13621 attgtcttct tataatggta agattgggcg actggccact gttgtttaat caagtcaggc
    13681 tgtaaggaca atgataagtc tcttttcatg ttgtcgggtt tcttgcgctt gtgcatgact
    13741 ttcggcgtta gctattgacg gactgacgga ctgacttatt cgctgctatt caatctcggc
    13801 atgtcgtggg aatccccagt caactacagt gtgggcggtg aagacctaga tctagatctg
    13861 ggtgcctttc tcggaagtct atcagatttc gatgggcaga ttgagccggc gcactctctc
    13921 gaggatgaat actctgggca atctgggcag ggcgccgatg acgaccccga ctcggatgga
    13981 ccgaaagttc tgaccatcat ggccagcata gatgccatcc accgtcatct agagaacgag
    14041 cgaaaaaagg ggaacgggaa ggctaatgtg gccatcaagc ttaaggatcc gacaatgcgt
    14101 aagagcataa ccttttcgat tccggaactg caaagcccta cgacaacagc atcaagtgcc
    14161 ggcagcccat cttgtgcacc gttacgattg ccgtccccag aagccttcga tctgggagaa
    14221 gcaatattct cacatcctac tgccgggtct tcgtttccag aagaggtcac tcccgcagca
    14281 gaggatgatg tgctgtccag catagcgagt ccttttgcta cgcccgaggg cctttttttt
    14341 ccccaggacg aagatgtgtt accaagcata gccccgttgc tgaaagcagc aaacttggcg
    14401 catgcaaccg aaccttctct tgggctcata tcgcccagag caactgcatc cgagtcttcc
    14461 atgatgccag acgaagaggc aatggccgac gttgtacagt accgcgatgg aactggtaca
    14521 acgccagaga gcctgtctcc aggagatatg gagcaggatg aatggcccca tacagtgtct
    14581 tcgagacaga ctcgttctcg tcaggccgcc agagcctgtc agactccctc caccatgtca
    14641 actaaggata agaaatgcat agattcatcc tcctgcagcc ttaagcaaat gaacagccag
    14701 caccaaaaaa gaaattccat cgagacagcg cccagccgga ccatcaagcg acctcgagtc
    14761 gagtcgcccg atctcctgac tctgattcct aaccacgatg agtaccagag agtccaagag
    14821 ttgactgctg cactggatcc attactcgca tacaagatgg tccgcaatgc cagggcgatt
    14881 ctaccccagt cggttgcgga ggacatggcg cactcagctg acatggaggt tgacggcccc
    14941 cttcactacc aaaataatca gcaatcccct tccagccaag aggaaattat gcagcagttt
    15001 tgcgagaccg ttcgcaggat agagtgggtg gaaagagccg cctttaaatc catggtggag
    15061 tacagagtac tgttcgttca actttaccaa cactacctga ggcttcagga gattgtggta
    15121 accaggaagg gggaaaggag ggtgacattg gccaaagagc aactctacag gacgctgtat
    15181 cccggcgttg agaagatgac aagcagcggc ctgacgagcg atgaatggga aaagttcaac
    15241 cggtgcattc gaagggggaa gcagtggaat acaatcgcct cgaagctggg cgtagggatt
    15301 cttcaaagga tgccatccag catttgccat tcatgggtgg aacagaagct ccagacaaag
    15361 gagcagcttc atatatggat agaaatagtt agccttctcg catagtctcc tcgcatagac
    15421 tccgatgcac agaatccgat gtatagtact tgtacggagc agagtccgaa gtttagctca
    15481 atatttgcgg ccttaagttt tgccgctgta acaattgata tgaaatctca caaaactccg
    15541 cgaccaacag ccaacaggtg aaacttgaac tgtgcgcgca tctcgtgtgg accttatctc
    15601 cgcgatgctc tcaacggcct cctcccccgc ccccagcgga ctttgatcgg ccacagcaac
    15661 agcttggcgc aagccagcga tcgagcaaaa gaaaaaaaaa tagcaaacct ctcagcctgg
    15721 ccctgccaag aatacaacac aacgacgatc aaagagaagt ttgcatacga aagcaaaagt
    15781 catggcacgg gccactctct ctttgagcga tagcagctcg caaagactca atacgagtgt
    15841 aacagcgggc ggaaattgtt cctaaattac cagttcgcca tatgcaccgt ttgcgtcgat
    15901 gaaacgaaga gctggacttg agaagcaggg cttggcagca tgagacgtag gtggcacaag
    15961 caaggatcct aacacgtgag atccgcgcct aacggttgtc ggcaagttcg ttccagttgg
    16021 atcctcttct cccatgtggc ggaaaggggg gacgattgtt ggacatggtt ttggggagtg
    16081 gcagtcagtt tcgagcacag gggcgggaag caggggagaa gcgtccgtgg tggtggcatc
    16141 aaaggtatac aaacaagcac ctcccccctc aaaacaggac cgaagcgccc tcacagcatg
    16201 ggggtggaac accgaatgct gacctttcaa gcctttactg ggcgccctgt ggtgtgtacc
    16261 cctgagtgac tagagatccg cataggattg cggatgcgat aggtcactta cctgagggaa
    16321 agaaaatact tgtagatgat gggggggtcc acgttcaaat ttgaatggat gccgaggtat
    16381 ttcctctcag tattccactt acgtcactcc gtattgtgaa tttgtcgaag acttgggaca
    16441 gtcagtcggt catgagtcag acccagacaa cttttgcgga cagggcccgt ggggcttggc
    16501 atggtaacac gagatgagac aacaaggacg aaacggggat cttcgggtta atgaggttgg
    16561 gtgagagggt cgtatcgcgc gtgcagcagg taggtagtat cgagtggcag acatgaagca
    16621 gtcttggaca gtaacaaaag tccacgaaca tacaccccga gctgcgaaaa gagggacact
    16681 gggttgggtt atcgtcgcga taggcaattg ctagtgacag attgactccg aacgtgagac
    16741 tttgaaggat tcctgctagc aaggtcaggc agatgccgga cttgagatca aattgtaggg
    16801 aacgcctgga gttgatgggc aagacgttac agtccccgat ttagggtagt gcacaccaac
    16861 tcacaaggct cggcctgggg cataagccgc catcccatcc ttcagctcca tagcacccta
    16921 acagaagtgc tgacatgtac tttgacacga tttgactcta tcgccggtat cagaggcgat
    16981 gaggaaaaat cgatctcata tctagatctg ttcgcatcta gtcaaagaac gtatcttgca
    17041 ttttcttgcc atccaaatca tttcactttt ccagtttgaa ctttgttcct ccacagccag
    17101 caagaatgag tgcatccaat ggcgagattg ttcagaggat tgaatctctg ctagcaagcg
    17161 ccaagaagct ccagggcgat gaccagtatg gccgctttgg gttgctcaag gagattgatc
    17221 ttctgtatca agacgtggag cctcccatca atacagtgag ttgtaacacg gcatactttt
    17281 gacgatttga caacagttgt tggctaatag tttcggtagt ttttcaagca gtggacttcc
    17341 gtaggagcat ttccatgtaa cttgtgtcac caaggtactg actctcgaac agttgacctt
    17401 tttctcttgc atcgatattg ccatcaagct ggggctcttt gagcacatga agggccgtga
    17461 aagtatcact gccaaagagc tcggtgctct tgtcaatgtc gacgacgatg tgattggtat
    17521 ttttcgccct cagtcctatc cccatgtaat cacagcggcg cactgacatt gatgttggca
    17581 cagcccgagt gatgagagtg ctcgtggcct ctcgattcgt ggcctcgaag ggcgaggatg
    17641 cctatgcgca cacgcacaag tctctggtct atgtcaaggg tgaacatacc gcagttgatt
    17701 cgttcaactt gatgtcagcg gcacgcctca tccgcccagt actccggtcg ctaacaatgt
    17761 cccgcgcaca gttccctctt ggccgtcagc tacatcacaa tccccgagta cctcaagacc
    17821 agatctgccg atgagctggt agacatccga aagaccccgt atgcctgcgc ctacggcatg
    17881 gagggtaaga ccttctatga ggtcctctct accaaccctg accatctgga taccttcaac
    17941 aggtcgatga gcgagcctgg tcccgagtgg ggcatgtttc cctttgagtc tctcagagag
    18001 aatgtcttgg ccgagccgga gcgcccgttt gtggtagaca ttggcggcgg aaagggtcaa
    18061 gctcttcttc gcatccagga agagacaggc aaagtgtttg gaacgagctc tcagctaatc
    18121 ctccaggaac gacccgatgt gcttgaacag atcaaccaag atgacattgc aggcattacg
    18181 aagatgccct atgacttcca taccaagcag cctgtgaaag gtgaggctct gttcagccct
    18241 actgatgtcg tgggaaatgc taacgcggtc tcccagacgc ccatgtctac ttcttcagcc
    18301 aaatcatcca taattatccc gaccacgtct gccaagacat ccttaagcag gccgctggcg
    18361 ccatgggccc ctcgtcgcgt ttgcttattg tggaggctgt cctgcctgcg caaaccgacg
    18421 ttggcggaga tatgggcgcc tacctgattg acgtatgtcg tgaccgtatc cgacgccgat
    18481 gttcagatga ctaacggacg atgtttgcag tttgttggtc ttgcgatggg tggcaaggag
    18541 cggaccgaga aggaatttgc gacgcttctg ggcactgttg gtttggagct ggtcaaggtg
    18601 tggcatggca aggcgagaca tcacgcaatt gtcgaggcac gattgaaaag agcgtaatgg
    18661 cccaacgatg acgggagtac ccagggagaa atggctaccc tagacgcaca ttaaaccggt
    18721 tttcggattt ttatgaagaa ctccgcatca acgaaatgtg cactcgattt aaccaatgtc
    18781 cgcatccgtc caagccaact ttgtgcatgt catccgcccc acacgcggcc ccaactcccg
    18841 cagctcattg gccagaagct ctgctttgtt tgcacaagga tataacgtgg gaatgaatcc
    18901 aactgcggag tcggaaatta tggtggaggg gcgggaatgc aaggttaagc ataaactccg
    18961 cagaggctta gggccaactc cgcaaagacg atcccagatc gggctccgca tttccgcaac
    19021 tccgcatggg tggtggagtt tggcgctaag acaaggcgtc gacagagact cggacggaga
    19081 aagggggggg ggcccgctcc aacggtttga cgtccaatct ggctgctact gttgggtccg
    19141 ccagagaagc aaaggatcga gcctgtccgc tgcgcactac cctaccaagc ctttctatac
    19201 ccagtggagg cattggcgtt tgtaaggagc ctcgaagccc gcgataactc agcataaacc
    19261 tgtcagatca acgtgtatta atgatcataa cctagagctc ccttggcctg tggcctgtca
    19321 gacaaaagcc gcccgacgaa agaggcaagt caatggcgtt tgccgggctt tcttccactg
    19381 ccgccagact cctctcacag cgggaactag ttgcggagga tactcaaact agtaagctgg
    19441 cggcacaaca cgggagctaa tcgaaccctc ccccctttca atcaagaaga gccttcacaa
    19501 ctaatcagta acttcatcga atcgcagaaa acacagtgaa tcaaaggacg ataacgataa
    19561 gagatcaaag aggaagaaga aaaaacagag atctcatcct tttacccccc tgcccctgcg
    19621 ggttgttgta ccacaaccaa cctggaggag tcgacggagt ttcgagatta agcatccaat
    19681 cacaacaact aaggggtgga tcctgcggcg tttctgttta ttgttattta tgccaatcgc
    19741 tcaagcattt tccttccctc ctcatctagc cctggcagca atcacttacg aaacttttct
    19801 tggtcgcaat ccgagatgga aaaacacgca gagccagaga agtccctcgg ggacaaggag
    19861 ttccaggaaa aggagctcca tgagaaacct gcgccagcag cctccgagga catcagcggt
    19921 gacagctcag tcaacaaaga ggatggcccc gatcccatca acgacaacta cttgagcggc
    19981 ctcaggctcg ccgtggtcat gtttgcgctg tgcatctcca acttcctcgt cgctttggac
    20041 accaccattc tcgccacggc cgtccctaag atctcttccg acttcaactc cctgcaggat
    20101 gtcgggtggt acacttcctc gtatctgctc accaactgtg cgttccagct gttctacgga
    20161 aagctgtata cgcgattcaa ggtcaagatt gtgtttaccg ttgccatgat catcttcgag
    20221 attggctctc tgctttgcgg cgttgcgcca aacagccctg tcttcatctt tggtcgagcc
    20281 attgctggtc ttggatctgc gggtgctttc tcaggcggta agtacccccc cctccggcct
    20341 cgtagcctgc tctgagagga ctcctttcgc taatttgctt gtgtagccct catcattgtc
    20401 atacactcag tgcaggccga gaagcgagcg caatactcgg gtatgattgt cggtatgtac
    20461 ggtcttgcat ccgtcgcagc accgttgatt ggtggtgctt ttacggatca cgtcacttgg
    20521 cgatggtgct tctacattaa cctcccctgc ggaggtgtcg ccattgctgg cctgctgttc
    20581 ttcttccatt ccccacctca ggcggctgtc aaggagaccg cggctggatt gtgggccaag
    20641 atcgctaagt tcgatccgtt tggcacattc ttcttcttgt gctctatgat ttgcctgctg
    20701 ttggccctgc agatgggtgg ctcgacctac cccttcaccg atgctcgcat catcgttctg
    20761 ctggtcttgt ttggtcttct gctggtcgcc ttcattgtcg tccagttctt cgacaagaac
    20821 gccacgattc ctcctagagt catgaagaac cgttccgttg cctttggcat gatttacatg
    20881 ttctgcgtgg gcgcccagtt cctggtcctg gtcaccttca tgccgatttg gttccagggt
    20941 gtccgcgcca tgtcagccac cgactcgggc atccgctcgc ttcccatcct gctctccaat
    21001 acattctgtg tcgttttagc cggtgccctg gtctccatga cgggatacta catccccttc
    21061 atgtgggcgt ctgtggtcct cacctccatt ggtgctggcc tgctcactac cctcactgtc
    21121 gatgcgagca caggcaagtg ggtcggatat cagattattg caggcattgg aggcggtctc
    21181 ggttaccagc aaggtatcag cgtggcacag actgtcctga aagggtcaga catgaccatc
    21241 ggcactgcgg tcatggtctt tgtccagctg cttggaggca ctattctcgt ttcggctgca
    21301 aacaatattt tggtcaccag gctcgttgag aacctggagc gccttgctcc tcacatcaat
    21361 cctgagatca tccttcgagc cggtgcttcg ggaattaaga ccgccgtcag cgaggccgac
    21421 tatccgtttg tcattgaggc atacaacatc gccttgacca agaccttcca gattgccttg
    21481 atcgtctcat gtctgggtgc gatcggcgct gctggtgttg agtggaagcg aggctcaaag
    21541 aagggagaca gcgacgagcc tgccattatg gccgtttagg agtaaaagct tttgtgtttt
    21601 tctttttttt tctatttttg tttcgtccaa gaaccgacgc atcgtttggt tctggttatt
    21661 tcttgccgtg aagagaggct cctgtactat tactttagat gcctagatct tcctccagtt
    21721 ttcgatttgc ataccctagg taggtatgga caataataca gacagattca gtcataaaag
    21781 ttggcctaca gtgcataacc atggatccat tatcacataa acaagggcac attctcttgt
    21841 atgcacatgc atgtatgtac tcttgttatc caaaccgcag cccgaccact gtggtttcta
    21901 caagtaatcg gtatctgctc tagttggtag gtaaccgaat gtggcaactt tgagaccgag
    21961 gtgacaatgc atcaaagttc atccatggtg ctgctgctgc ggaataaatt ccctgctggt
    22021 tgtctcagtc tcagttctac aattccagcg tggtgtgggc tgagttgaca ctgaaatcct
    22081 acaacaccct acctacctac acacccaagc caccctgttg agtctctgag tacttgtttt
    22141 gttttagttc ccgtcctatt cttttcattg tacgcggaca atgatgatgc agatggagaa
    22201 tctaagcgca aaggaccctg acgagggtct cggaggtgta tcttgatctt cggccgactc
    22261 ccggttacag acactgtcgt ttacctatta taatgataga ctcatcccac agcgctatgg
    22321 cattctcagc tatccaacca tctcagttta ccgttgccgc tgcaccagta actcattggc
    22381 attggcgttt cccaaaatgg cggacacaag tatccaggat gcgatcacca aggctgcgga
    22441 catcatgtcc acttctgact ttgtcaacaa ggacgttttt ctcattatcc caaggatcca
    22501 gttgatcgat gcaccaaccg ccgaaaaggt aagagtgacg gccgactgta gaccgcagtc
    22561 gagccctgtc tgcctctcaa ctgattcatg tctaactatc tatagtatat ccgagacttc
    22621 aagcccatca gcgactttgc tctcgaacag gagccgggca cgctcaaatt ctgcgcactg
    22681 cagccgcgtg gccagggtaa aggcaacgag gtttttgcct tggagcagta aggaaccccc
    22741 ctccccctgc ttgggctctt ccctctctgc cgctcgcaaa tgcacgaacc atgtatattg
    22801 acacatgcat cacagcttcg actcggcagc ctctctggca aagcatcgag aatgccccct
    22861 cgtcggagat atgctaactt ggttgctaac ggccaagccc aatggagatt accccatccc
    22921 ccctctcgtc cctctccaaa tcttggatcg ctttgtcagg cctgctttga aggcggccca
    22981 ggatccctat gttgtaatga ctcaaattgg ctttgagcca gagggggcct ctcagattga
    23041 ggcagggata gctgcatatg gtcatttagt cacaaacacc gaagctgtcc tgatggttct
    23101 gcccggaaag gcagacaagg aagcttgggt tacgattgcg tatctagaca gacaagccta
    23161 tgaggagagg ggtcttgtcc aggaagggtt cgcagagggg agcgtcaaga gctggaatga
    23221 gcaccacttg gagctcaagg cagggtttct gctgcagtaa gactctagat tcggtggata
    23281 gtcctctcta tcatagatta ccaagaattg tctctttgca aatgaatgaa ctgacgtcaa
    23341 ctccatgttt tgttgagggt cgactcttgt gttcctgtgt aagtgagcat tgtgaagatg
    23401 gggtgcgcaa tctggctatg cagccaccgt ctggtgctgg gtccaacccc tcagttccct
    23461 gcaaggatca tctcgtatgc cgaatccttg ctctaaattt cggctgggtc atcctttctg
    23521 ttgccctgtt ctcctcttga tgtatcaaag cgacctgggt tcaagccgtg tcttgactct
    23581 ggctataccc cccccccccc ccccgctttg agatgttgcc ttttgaaagc atcgcggcgg
    23641 agaaggatcg gggcgtccat cagcttacag tggcactgat cttgactccg catgataagg
    23701 catttgatac attgtgtgaa ataatttgta tgctaatagc tgcatatggg atgtagaatc
    23761 cgcatcggaa ctatagcctc cttccttaga agagtccaac aacgatacct agatctgtgt
    23821 ttccccttta ttagagagac tttcatttgg gtaatcatta ttgtgatata gaatcttgtc
    23881 ttacatacaa attttgttgg ccatctaaac atcttgtttc aatttcccca gacgtacctg
    23941 acaaaaatga cgagagcaat actgccagac gtgagccctg actccattga ccctcagttt
    24001 ctagaggaga aatatgatca agagcgtctg aagcgtatca acgcagcagg ttatgccaag
    24061 tatagtgagg ttggagatgg cgaactggaa cgcttcaaag tgacccatcg tctcgaggat
    24121 gtggcttcaa gtcgagagcc cgtttcggtt gataccgacg tggtcatcat tggcgctggc
    24181 tatgctggaa ttctcactgc tgtccggctt gttcaaaacg gtattctcaa cttccgaatc
    24241 gtggaaaagg gcaacgggtt tggaggtaca tggtattgga atcagtatcc aggtttgtga
    24301 acaggtcctt tgtggaattt ggctgagttg ctaacatgtc gatttctagg agctcaatgt
    24361 gatgtagaat catacattta catgcctctt cttgaagaga ctggctacgt accaacggag
    24421 aggtatgctc gaggcccaga gatcttgaag catatcaact tgatagccaa gaaatgggaa
    24481 ctcgcaccaa agacgcattt ccagagtgag gtctctgcag cagactggac tgcagaccga
    24541 tggactgtca agactcgcca aggcgacgag tttcgttcca gatacctggt cacagccatt
    24601 gggcccttcc acagacccaa gctccctggt gtccctggca tcaactcgtt caaaggtaac
    24661 actttccact ccagcggctg ggattacgag gccagcggag ggagtgcgac cgagaaactg
    24721 accaagtttt cggacaaaac cattggcatt attggcacgg gggcgactgc tgttcagatg
    24781 ctgccgtttg tcgcgaattc tgccaaggag gtgctcgtct ttcaacggac gcccgccccc
    24841 gtcaatgtcc gcaacaatgg ccccacgcct cctgattttg ccaagttttt ggaaccaggc
    24901 tggcagcttc gtcgcatgga taacttcaac aagatctata caggcgaacc aatcgacacg
    24961 tccatagtgt cagaggagtg gctgtcagca accctccagg ttctcttcgg cacagagtct
    25021 gacaagccaa gcgaccccgc cgagcttgag cagctcctgg ctcgaactga cttccaagtg
    25081 atggagcgaa tccgcaggcg agttgacgag accgtaagcc cacctgacgc ccctcccccc
    25141 cctttctccg ttccgtctta catgacatca tatgggtcct gctcactaat ccatgactat
    25201 gtagattaaa gatccagtga caagggagca gttgaagcca tggtatgcta caatttgtaa
    25261 gaggccatgt tttcacgatg agtacctcga gtgcttcaac agacccaatg tcagactggt
    25321 cgacacagac ggcaagggcg ttgatcgcat caccgaggac tcagttgttg tcgatggcaa
    25381 ggagcatcat gttgacgctc tggtattttg taccggattt gagtacctct ctggtgttga
    25441 tcgtcacggg ggcttcactg tcactggcaa ggatggcgtt actctcaccg agaggtggac
    25501 ccctggcccc agtacctacc acggactcta cgttcatggc tttcccaact tcttctgcct
    25561 tcaaaccgcg caggctggca caaacccgaa cttcatgtac acggcaacta ctggatcaac
    25621 gcaaattggt catgttattg ccgagtgctt gaaggacggg gtccgtgaag tccagcctac
    25681 taagcaggct gaggatgact gggtgaagat gattctggaa ggaggacggg gcatgatgca
    25741 tttgatgaga aattgcactc ctggctacat gaacaacgac ggaaatctcg atgagaaaac
    25801 agccagaaga atgttctatc ctggtgggcc aactgcctgg aggaaactcc tcgaggcgtg
    25861 gagggagaag ggagacttcg agggtctcca gagaacctat tagattagaa agacattaga
    25921 ttagactcaa attctggtct gattctctgc gattttgcca agtctgttgc cgtagaccca
    25981 tctagatcct atccttgaag ccctcgcaac aattagtcat cgccaccaca tgcgccgacc
    26041 ggcggttgcg cgcgaggata catgtactca actccccttg cttatcatga tacgactatt
    26101 tcctatccat atggcatcca atatacttag ataactatta ttaatttctg cgcataccca
    26161 agatctcgca taatgttggg aagtaaatcc ttccgaaaag ctacgtcacg tacatcttca
    26221 taaccggtag ccctaccagt aacgctccca tgttccggca gggcgcctac tctggcaaat
    26281 ctgatccttc tgtatcccgg agaagcaact cccactatgg attgacaaaa ccccgctcgg
    26341 ggcacaagcc catcagattt gaccagctcc aaacggagga gataagcggc attaaaccca
    26401 gttgcttccg gaagaggata ttaccggccc ctcacccaat ctgagttcat cgacggaaga
    26461 acgggaagcg accagggaca gggcagtctc atatgactgg tcgccttgca cattggttcg
    26521 gtgccggtga tgagaaagtt cctcgcggca tagggtatta cgttgtctcg gccggggggt
    26581 acaaggcgct tgacatgttc cgcccctagc atctgccttt ttttgccgac aacaacaaac
    26641 ctcgttgcat aagcccgtgg cgtttttttc ctactcggat caaggtcata catgccgtct
    26701 gctccttcga ggatgctgta acacccatct gtccaaatct caaagtggaa tagggcgatg
    26761 gtactacatc cgccttcacc ttgatgaagg attgttgggg atggcaacac cattggccta
    26821 tctaaagctg gcgtgtttgt ttttgcactc agggtacgtg ttgtagaact tcgtatgcct
    26881 atgtactcat tgctatagga ttgtcatagc tcccgatcct agactggaga tattcgtgtt
    26941 gtgagtcagg tagtgtcttg aagatctcgg agttgagaga ataggaaaaa gatatgtgct
    27001 atctagaaat gtaacgataa ctaaggaata cattctaaga aactctaggg attgaaccag
    27061 aaggaaaggg attttacgtt atggttaacc aaaattacaa tggaactacc caaactggcc
    27121 atatcgcgac tcgaagggaa gcatcaatgg ccacctggtt cattcgtagt ggcgtgggat
    27181 ctgaaggcta gctgtgtatt ggtatctagt aggattattg ccttgaccgt tcaaacattc
    27241 tttctatagt tatctacaat tgttttacat cgagtacatt cttccccgtc tccacaaccg
    27301 gtcgcccgat tctagcgtga tatcggaggc aggttgcttg cctacagggc tgtgtctgta
    27361 tgtgcttaca tgcactgatt aagaggtatc atctatagat ccatgtagac atagatacgg
    27421 gttcttgtct atcttcctgg gtgaacagca tcaactcgga gactctgagt ataaatatca
    27481 tatatctggt tgcttcttca gagctctcta taggtttctt tttcttcaca tctcatcctt
    27541 actctcccac atctctaaga cacaatgcct tctaccagca atccatctca cgtccctgtg
    27601 gccatcatcg gcctggcatg ccgattccca ggcgaggcca cctcaccatc aaaattctgg
    27661 gatcttctta agaatggacg aggtatgttc tttgagctat ccctgactct tatgttatct
    27721 tgaatcttga gaagtttttt tatgatatgg ctctttgcta acgctctgcc ttgaagatgc
    27781 ctactcacca aataccgatc gatataacgc tgatgccttt taccatccca aggcaagcaa
    27841 ccgccaaaac gtgctggcaa ctaagggcgg ccacttcctc aaacaggacc catacgtttt
    27901 tgacgccgct ttctttaaca tcacagccgc tgaggccatc tcctttgacc ccaagcagcg
    27961 aattgccatg gaagttgtct acgaggctct agaaaatgcc ggaaagacac tacccaaggt
    28021 ggcgggcaca caaactgctt gctatatcgg ctcttccatg agtgattacc gagacgctgt
    28081 tgtgcgtgac tttggaaaca gccccaagta tcatatcctg ggaacatgcg aggagatgat
    28141 ttcaaatcgt gtgtcccatt tcttggatat tcacggcccc agtgccacca ttcatacagc
    28201 ctgctcatca agtcttgttg ctacacactt ggcttgccaa agtttgcaat ctggagagtc
    28261 agaaatggcc atcgctggtg gtgttggtat gatcatcacc cctgatggta atatgcatct
    28321 taacaacttg ggattcttga accccgaggg ccactcccgg tcatttgatg agaatgctgg
    28381 tggttacggt cgtggtgagg gttgcggtat cctcatcctc aagcggctag acagagctct
    28441 cgaagatggt gattccattc gcgccgtcat tcgagcctct ggtgtcaact ctgatggctg
    28501 gacacagggt gtcaccatgc cctccagcca agcccagtct gcccttatca aatacgtata
    28561 cgaatcgcat ggcctggatt atggtgcgac tcaatacgtt gaggctcacg tgagtaaatt
    28621 cgatgataac tatatgattt gcaagttagc tgacagacaa ttgaaatagg gtactggtac
    28681 caaagccggt gatcccgcag agattggcgc cctccaccgc acaattggac agggcgcgtc
    28741 caagtctcga aggctttgga ttggcagtgt caagccaaac gtgagtttag aatacgacgt
    28801 gaccatttgc actttcacct tgctaacctt tgctagattg gccatcttga agccgccgcc
    28861 ggtgtggctg gtatcattaa gggcgtcctg tccatggaac acggcatgat tcctccaaac
    28921 atttacttct ccaagcccaa ccctgccatc cctcttgacg agtggaacat ggccgtgcct
    28981 accaagttga ctccctggcc cgccagccaa actggtcgcc gtatgagtgt cagcggtttc
    29041 ggtatgggtg gtaccaacgg ccacgtcgtc cttgaggcct acaagcccca aggaaagctc
    29101 accaacggcc ataccaacgg catcaccaat ggaatccaca agactcgcca cagcggcaag
    29161 aggcttttcg tcctcagcgc ccaggatcaa gctggcttca agcgtttggg taacgccctg
    29221 gtggagcatc tcgatgccct gggccctgcc gctgccaccc ctgagttcct cgccaacctc
    29281 tcccacactc ttgccgttgg cagatctggc ttggcttgga ggtccagcat catcgctgag
    29341 agcgcccctg atcttcggga gaagctggca actgatccgg gtgagggagc cgctcgttct
    29401 tcaggcagcg agccccgtat tgggtaagtt tcttgacttg atcaggccaa tgttcgctgc
    29461 taactttggg aaatagattc gtcttcacgg gtcaaggtgc tcagtgggcc cgcatgggcg
    29521 ttgagttgtt ggagcgcccc gtcttcaagg cttccgtgat taagtccgcg gagactttga
    29581 aggagctcgg ctgtgaatgg gaccctatcg ttgagctttc caagcctcaa gctgagtctc
    29641 gacttggtgt tcctgaaatc tcacagccca tctgcacagt cctacaagtc gccttggttg
    29701 atgagttgaa gcactggggt gtatcacctt ccaaggtggt cggtcactcc agtggtgaaa
    29761 tcggtgccgc atacagcatt ggcgctcttt ctcaccgtga cgctgtcgcc gctgcttact
    29821 tcaggggcaa gtcttccaac ggagccaaga agcttggtgg tggtatgatg gctgttgggt
    29881 gctctcgtga ggacgctgac aagctcctct ctgagaccaa gctcaagggc ggtgttgcta
    29941 ccgtcgcatg tgtcaactcc ccctccagcg tgaccatctc aggcgatgcc gctgctctcg
    30001 aggaactccg agttattctc gaggagaaga gtgtgtttgc tcgaagactc aaggtcgacg
    30061 ttgcctacca ctctgcccac atgaacgctg tctttgccga atactctgct gcgattgccc
    30121 acattgagcc cgctcaggca gttgaaggtg gaccgattat ggtctccagt gtcactggta
    30181 gcgaagtcga ctctgagctt ctcggccctt actactggac ccgtaacttg atctctcccg
    30241 tcttattcgc cgacgctgtc aaggaattgg ttacccctgc tgatggcgac ggccaaaaca
    30301 ccgtcgatct cctgattgag attggtcctc acagcgctct tggtggccct gttgagcaga
    30361 ttctgtccca taacggcatc aagaatgttg cttacagatc tgctcttact cgtggcgaga
    30421 acgctgttga ctgcagcctc aagcttgctg gcgagctctt ccttctcggc gtgccctttg
    30481 agttgcaaaa ggccaacggt gactctggtt ctcgcatgct cactaaccta cctccttatc
    30541 cttggtaatt atagccccta ttggagtcaa agaaaagcat tcaggtttgc taacattgtc
    30601 ataggaacca ctccaagtca ttccgtgccg actctcgtct ccaccgtgag catctggagc
    30661 agaaattccc tactaggagt ctcatcggtg cacctgtccc catgatggca gagagcgagt
    30721 acacatggcg caacttcatc cgtctcgctg acgagccttg gctccgtggt cacactgtcg
    30781 gtaccaccgt tctgtttcct ggtgccggta tcgtgagcat catcttggaa gctgctcaac
    30841 agctggtgga taccggcaag accgttcggg gcttccgaat gcgcgatgtc aacctcttcg
    30901 ccgccatggc tctccccgag gacctggcta ctgaggttat catccacatc cgacctcacc
    30961 ttatctctac tgttggatca accgcccccg gtggatggtg ggagtggact gtttcctcct
    31021 gcgtcggaac tgaccagctg cgagacaatg ctcgcggtct ggtagccatt gactacgaag
    31081 agagccgcag cgagcagatc aacgccgagg acaaagcgtt ggttgcttct caggtcgcgg
    31141 actaccacaa gatcctcagc gaatgccctg agcattatgc tcatgacaag ttctaccagc
    31201 acatgaccaa ggcctcttgg agctacggcg agctcttcca gggtgtggag aatgtccgtc
    31261 ctggatacgg aaagaccatc tttgacatca gagtcattga cattggtgag acctttagca
    31321 agggacaact tgagcgacct ttcctcatca acgctgccac tctcgatgct gtattccaga
    31381 gctggctcgg cagtacctac aacaacggtg ctttcgagtt tgacaagccc ttcgttccca
    31441 cctctattgg cgagttggaa atctctgtca acattcccgg tgatggcgac tacctcatgc
    31501 caggccactg ccgctctgag cgatacggct tcaacgagct gtctgctgat attgccatct
    31561 tcgacaagga tctgaagaat gtgttccttt cagtgaagga tttccgaact tccgagcttg
    31621 atatggattc cggcaaggga gacggagatg ccgctcacgt cgaccctgcc gatatcaact
    31681 cggaggttaa gtggaactac gctcttggcc tcctcaagtc cgaggaaatc accgagctcg
    31741 tcaccaaggt cgccagcaat gacaagctcg ccgagcttct ccgtctgaca cttcacaaca
    31801 accctgctgc cactgtcatc gagcttgttt ctgatgagag caagatctct ggcgcatctt
    31861 ctgccaagct gtccaagggc cttatcctcc ccagccagat ccgttacgta gttgtcaacc
    31921 ctgaggcagc ggacgccgac tctttcttca aattcttctc ccttggtgag gatggtgccc
    31981 ctgtcgctgc tgaaaggggc cccgccgaac tgttgatcgc ctccagcgaa gtcactgacg
    32041 cggctgtcct tgagcgcctg attaccttgg ccaagcctga tgccagcatt cttgttgctg
    32101 tcaacaacaa gactaccgcc gctgccctct cagccaaggc gttccgtgtt gtcaccagca
    32161 tccaggacag caagtccatt gctctctaca ctagcaagaa ggcgcctgcc gccgacacct
    32221 ccaagctcga ggccatcatc ctcaagccaa ccactgctca acctgccgcc cagaatttcg
    32281 cctccatcct ccagaaggca ctcgagctcc agggctactc tgtcgtttct cagccatggg
    32341 gcaccgacat cgacgtcaac gatgccaagg gaaagaccta catttctctg ttggagcttg
    32401 agcagcctct gctcgacaac ctctccaagt ccgacttcga gaacctccgc gcagtcgttt
    32461 tgaactgcga gcgtctcctg tgggtcacag caggtgacaa cccatctttc ggcatggttg
    32521 atggtttcgc tcgctgcatc atgagcgaaa ttgccagcac caagttccag gtcctgcatt
    32581 tgagcgctgc aactggtctg aagtacggat cttctctcgc cacccgcatt ctccagtcgg
    32641 atagcaccga caacgagtac cgggaggtcg atggtgctct ccaggtggcc cgtatcttca
    32701 agagctacaa cgagaacgag agtctccgcc accacctcga ggataccacc agcgttgtga
    32761 ctcttgctga ccaggaggat gctctgcgcc tcactattgg caagcctggt cttttggata
    32821 ctttgaagtt tgtccccgat gagcgtatgc tcccacctct ccaggatcac gaggttgaaa
    32881 tccaggtcaa ggctactggt ctgaagtaag ttccccagca tcgtgattaa tgggcacatg
    32941 taaggatgta ttgctaacag cttcttagct tccgagacat catggcttgc atgggtctta
    33001 ttcctgttcg atctctgggc caggaggcca gtggcatcgt cctcagaacc ggtgcgaagg
    33061 ctaccaactt caagcctggc gaccgtgttt gcaccatgaa cgtcggaaca catgccacca
    33121 agatccgagc cgactaccgt gtcatgacaa agatccccga ctccatgacc tttgaagaag
    33181 ctgcctcggt tgctgttgtt cacaccaccg cctactacgc cttcatcacc atcgccaagc
    33241 ttcgcaaggg ccagtccgtc ttgatccacg ccgccgctgg tggtgttggc caagcagcca
    33301 ttcagtaagt gttcagaaga aacctgagaa gtattttttg gcaaggacat ccaaagtgct
    33361 aatacaatga atctaggttg gccaagcatc tcggcctcat cacctatgtt accgtaggta
    33421 ctgaagacaa gcgccagctc attcgggagc agtatggcat tcccgacgag cacatcttca
    33481 actcccgtga tgccagcttc gtcaagggtg tccagcgtgt taccaacggt cgcggtgtcg
    33541 actgcgttct caactctcta tccggtgagc tcctgcgtgc ttcttgggga tgccttgcta
    33601 cctttggtca tttcatcgaa attggtctcc gtgatatcac caacaacatg cgtcttgaca
    33661 tgcgaccttt ccgcaagagc acctccttca cattcatcaa cacccacact ctcttcgagg
    33721 aagaccctgc tgcgttggga gatattctca acgagtcctt caagctcatg ttcgctggcg
    33781 cccttaccgc tcctagcccc ttgaatgcct atcccattgg ccaggtcgag gaggccttcc
    33841 gaaccatgca gcagggcaag caccgcggta agatggtgct gtccttctcc gatgacgcaa
    33901 aggctcccgt gttgcgcaaa gcgaaggatt ccttgaaact ggaccctgac gccacttacc
    33961 tctttgttgg tggtcttggt ggtctgggtc gcagtcttgc caaggagttt gttgcgtctg
    34021 gcgcccgcaa cattgccttc ttatcccgat ccggtgacac taccgcccag gccaaggcta
    34081 tcgtggacga attggctggc cagggtatcc aggtcaaggc ctatcgtggt gatatcgcca
    34141 gcgaggcatc cttcctccag gctatggagc aatgctctca ggatctcccg cccgtaaagg
    34201 gtgtgatcca gatggccatg gttctccgcg atatcgtctt tgagaagatg tcgtacgatg
    34261 agtggaccgt ccccgttggc cccaaggtcc aaggttcatg gaacttgcac aagtacttca
    34321 gtcatgagcg acctcttgac ttcatggtca tctgctcctc aagctccggt atctacggtt
    34381 atcccagtca ggctcaatac gccgctggca acacttacca ggatgccttg gctcactacc
    34441 gtcgctctca gggcctgaac gccatctccg tcaacttggg tatcatgcga gatgtcggtg
    34501 tcctggctga gacgggtacc actggtaaca tcaagctctg ggaagaggtc ttgggcatcc
    34561 gcgagcctgc cttccacgct ctcatgaaga gcttgatcaa ccatcagcag cgtgggtctg
    34621 gggactaccc ggcgcaggtc tgcactggtc ttggtactgc tgacattatg gctactcacg
    34681 gcctggcccg gcccgagtat ttcaatgacc cccgttttgg accccttgcc gtcaccactg
    34741 tcgcgaccga tgcttcagct gacggccagg gctctgctgt ctcgctcgcc tctaggctct
    34801 ccaaggtttc caccaaggat gaagctgccg agatcattac cgatgctctg gtcaacaaga
    34861 cggcagacat cctgcagatg cccccctctg aagtcgaccc cggccgacct ctgtaccgtt
    34921 atggtgttga ctcccttgtg gcgcttgagg tgcgaaactg gatcacaagg gagatgaagg
    34981 cgaacatggc gctgctggag attctggcag ccgtccccat tgagagcttc gctgtcaaga
    35041 ttgctgagaa gagcaagttg gttactgttt aaggcgttta cggagggggc gggatggttc
    35101 cgaaggactc aaggttgctt tgctattttc tttttggtta aggggtttag ggttttagtg
    35161 atcttacgcg tatcatgatt gtgctttact tgttaaggat agtttctaga acaatggatc
    35221 tgatttctca gtatttgcct cattgggatg ccattttccg acgcagagtg agacatttgt
    35281 ccactggaaa ctccgagcac tcactgcaag tagcctcttt ggcgtaaacg gaaacgagtt
    35341 tgacgatggt tccaggacga agaaaaaccc acccgtggcg cgtggggaat gtaatttcgg
    35401 aacaaaggcg aatagcctct cggtgtgcaa agcccaatat gagaaaacat gttataccta
    35461 gtgatcagtg atcatgggga actcagctgc tagtgaagat cgtgagatcc atctgactcg
    35521 gcctgtcggc ctcgccaatt gaacatcaaa tgctacttgt attccgtatg tggctgaaag
    35581 aggaggtctg gtgtttggga gatctgcaca tacggagtac gacagaggaa gtcctgcgga
    35641 gaatgggaga agccaaccac ccatcagggc tggctacttg cggcttgtgt tgacacgacg
    35701 ttcgatgggc tacaagtaag ttgtaactac tccgcagact ttctagagga gagcccggcg
    35761 ggtttactcc ttggtcctga ctcctgagtg cctggcgacg aacactcact tacccgcgaa
    35821 cgtgtttcac cgaaactgga tacatccatc gggacaacat ttgtcgaatt acccgcgggg
    35881 ggcgcatgga cgataatttt gattcggcca gatgtccgac ccattctccg agatggcaat
    35941 tccttttcaa taaaaagggt tgggttggac cttgggaact ggcagaaaca tctgtcggca
    36001 tggattctgc tgcgcgtgct tccgcgagac cttccagaat ccttccacca tgttctgcat
    36061 aataagagcc cagctattat tattattaca cttgcttgta ctggctctgc tgttggttgg
    36121 cacagtttgc aacgctcacc cccaacatgg ccatccatcg gagctggagc cactagctct
    36181 caaaaggggt ggctcgcctc gagatgatgg caatactctg gcgccgcggt gcagatgcgt
    36241 aagaatatcc taagagcgtc tcggcgcgta gataacctgt ttcttggctg ttcgttttgc
    36301 gctgacgctc taggaagata cctggcgagg cgtgctggcc atccacccag atctgggatt
    36361 cgttcaacag gacgatcggc ggcagcctga tcaagaccgc acccctcgca gagtcgtgct
    36421 accctggccc aaaaaagaac accaggaaat gtgccgtcgt cagtaggaaa tggacagatc
    36481 aggactttca gacggatagc cctgtaggac gaacgtatcc gtacaacatc acatgcgccc
    36541 ccgtcaacta cttcgccggc caacgcccaa cgacctgcag cctgggacag cttccggtgt
    36601 acgcaatcga cgcaaggact cgtcaatctg tggcacaggg actgcgcttc gccaaggaca
    36661 ataacctccg agtcactgtc gtcagtacgg gccacgactt gctaggcagg gcggatggct
    36721 atggaagtct cgagatttgg ctccgacatc ataggaacga gattcgcttc gagagacagt
    36781 acatggcaac ggatgggtgt cgcgagtctg gctggaccgg cagcgcgatt gatatcgacg
    36841 gcgcatacca gtggcgagac gtccatatca aggccagggc caacaatgtg atagttgttg
    36901 gaggcggctc ggtgtcaccc ggtgctatcg gaggctggcc atccggaggg ggccacggtc
    36961 ctgcgtcgcg caactacgga ctcggcgcgg atcagatcct tgaagctgaa gtgatgctcg
    37021 ccgacggctc agtcgttctc gcaaaccact gccaacacac cgacctcttc cgtgccctca
    37081 ggggaggcgg tcctggcttc ggcgtcgtgc tcaaaactaa gattaaagcc tatcccaatg
    37141 tcgcttcggt atcggtgcat catctcacca tcacaccgat ccgccaaacg ccaaacaatt
    37201 ccgatctgtt ggacgcggta gctgttttga tgcaggctta tccgaaactc agcgacgatg
    37261 gatacgccgg atatgccttc tggctccgca actgcaaatc gttctttatt ggaagcgcga
    37321 agtccgggta ccgccacggg atttggatga ttggaaagac aaccgaggag gctgaacact
    37381 cattcgcccc tgtacgagag gctttggaca aattcaagtc caagctgacc atctcggagt
    37441 cttacatgac gtataacgac tactggtcgt tttatacatc tgaatcgggg ctgtacgaat
    37501 ctgttgggac aacatcagtg ttgacttcgc gccttatcga tcgacctgct gtggaggatt
    37561 acaatcgagt tcgtgaggct gttgaagtta ttggtggcaa accggaagac tatgccacca
    37621 acgtgatgat gttggtctcc aacggacaag tctttgcaga cgcggcagac aagtcatcgg
    37681 gattaaaccc agcctggcgt gtatctccat acgtggtcat cagcagccga ggcataccca
    37741 tggttgtcga tcaagcatca cgcaaagagg tagcagacga catcacatac gtcaaagggg
    37801 ccgccttgca gaaactcgcc cccaatacgg ggggctacat gaacgagggt gacagaaatg
    37861 accccaacta catcaagaac ttcttcggga ccatctatcc cacgcatctc gccacgaaga
    37921 agaaatacga cccgtggggc ttattttact gtccgacgtg tgtcggtgca gagctgtttg
    37981 aggagacttc tcgaggggaa ctgtgtaggc gatgataacg acttttatga cgcatcatag
    38041 aattatcacg gttggcgttt gctttttttg aaatatgaat atcgagcatt tagtagggat
    38101 gggtatgcat caagtgagcc ttgattgtaa aacaagtcaa atagagtcat agacactgtc
    38161 ctatcgacag ccatcatgac aaataactat atatatgtat gttctgctga gcagtcagaa
    38221 gctccatccg cttctctcta aagttctagg gaatcatcga aagtcattac aaattacgtt
    38281 tcactcattt gaccgcagcc cgcttcggtc tccttgtcgg ttcctgttgc taccagttga
    38341 acatctcctc aaacacctcg atatcgttgt acccgctctt gacttgcttg atcacagcca
    38401 atcttgtctt gtctgccatc tctgcaggtc cgcagacgaa gatggccgtc cgcccggggt
    38461 ggctctctgc gaaattgtga acgagggcgt cgacgtcggg tcgctcgcgc ctgaatcggg
    38521 tatcctgtgt gtatttctca tcaatcgtcc caccattagt gatataaaac tccatggcca
    38581 gcttcgtggc tgccgcaggt gcgctttcca cccgcctgag gtcatttgca agcacatcgc
    38641 ggacgaagcc ctcgtggcgg accatccagg ccagcttcgt gttgggaatt cttcctccat
    38701 tatacccatc ttcgaagaac atccgaaggt aaggtagcac tgtcgtgata ccactgcctc
    38761 cggtgatgaa gaggacgttg tcgaagttgt taaaacgcgc aggtgtgccg taggggccct
    38821 cgatgtagac ccggactcga cgttgcccgg atgaaccctc tcccctgaga gagtctctca
    38881 atcgtttggt cattccatct cttggtttga tcatgaaggt catgtactgt tcgctcttgg
    38941 tgacactgaa ttccgtaata cgtggcgatt gtacacgctt ctcgccgtca gtgtccctgt
    39001 cgctcagctc agacgaggat gtaacatctt caatctcgga agatcgacca gccaatgtga
    39061 acggatgaca ctcccaaacg cgccagccgg gaaaatacat gtaatagtac gttccagggg
    39121 tttgctggtt ggcagccacg gatgggttga cctggaggcg aatcattccg gtttcttcgc
    39181 tgtagctggc caaagccgga acatctttgc caaggaatga cttgtagttc atcaaaagga
    39241 cacggagtaa tcgcatcaca tggtctccgg cccagagacc gatgctcgcc caagcccaaa
    39301 cggcgtaaga tcctgagaat tgagtcttga catgtctgta gaagtaatta gcattgccgc
    39361 tactaaataa ggctcgcaag aagcttactg gtagtaagct gccataaaga tggccgcaaa
    39421 tacaacatgc gtggtcttga agaattcgta tgctttttgt cgaatagggc cgagagcaac
    39481 gaagatggca aggcccatgg ccgtcagcat ctactaatgt cagaattggg catctagacc
    39541 gaaatgtgtg cgtggtcagt gacgcatacc attataccgt agaggaaaat ctcatcatcc
    39601 tctaaattct ctcgataagc atcccatccc tgttctgtaa caccttgtca gcaatcgcct
    39661 cggctgtaga tcagcaaggg ggacctgcca gtcacatagt aggcggaaaa tgccaccccg
    39721 tgaacgatcc cctgaactgt caaaacaatg gacacccagc ggtggaatat gttgaaggtt
    39781 ctgtaactcc acccggtagc aagcatgagc acgttggctc ggcccccaaa gatgaaaaca
    39841 aacggtagtg atgcggccat catatttcca agtcggtcgg acaagattcg caacacttgg
    39901 ccctttgtcg ttttatagct aagggaatgc cttggtgagg tttgaggaga aggatctagg
    39961 ataggagaaa actaacttgt agttgccatc gatgataatg tagtgggttg ccagcacgag
    40021 gacattgatg atgatgtatg aagcaatcac catggactgg aaacgaagag ggactgtgaa
    40081 ccaacccaag gactggtggt gatgatagtt gaacgtcggt gacatgaaaa tattggctct
    40141 gagccaagac ttgacacccg agcttctgtt ttttgtggga gcatcgactt gctttgctgg
    40201 aatgaacgac catgcgtgag taagtgctcc accgaggacc acgagccccc agaatgcgta
    40261 aagaatccat ctatgttatc tgtgttagta tacgaacaat agctccgtac atgatccagc
    40321 acgtcttgta aagctacctg atgttgagat tgtataagcg tagagtgttg taagtattga
    40381 gagatcgatt gatgaggtcg agactcggtg gtgatggtgt gattaagttg ttcaggacgg
    40441 ctttctcatt tgatccaact gtcgggagtc cggccaggta ctcagcagtg acactgtctg
    40501 tagtcttgtg gtaggcggcg aggttgacga ctttagcaga gcccttgcag gcccctgccc
    40561 accacgcaat acccggctcg agatctgcct cctgacactg cgcccgcgcg caaaggaagg
    40621 ttgagtttac acgaagaggg ttcgtgcata gcgtctgttc tgtttcattc ttggctgtga
    40681 acttgagctt caatagggag tagtagcaac cagcgacaca gatctcctga gtcacaggtt
    40741 tggctgccag ggcacaagcc gcaaagagca ggtagagtag gaacggaatt cgagtgaaca
    40801 tgacgtctgc cgctgatgcc ctttcgaaac gttgtcctcg tccagaaaca agccaagtgt
    40861 aaccagaaag ggggtgtcag gactgcagcc cttgttatat gagcttgaca ggagactgcc
    40921 agcccaaccc aaacgctaca tcgtcgctcc acctggggat ctcagagacg tgaaacccac
    40981 acggaatgct acggagccat gttttactca cgcaaacctc atatcaagca accttgcagc
    41041 atcggagctt gatgcagaag acactaatcc atgcggtacc cggttttcca gtccttgaga
    41101 gaatagtgcc atcgtcctgc cttatcggag tcaaaggtct tcgaagtcgg agtcggcatc
    41161 ggcataacgt tggagaatca tctcgatggg aacccacata agtttgttgg aaacgtttac
    41221 ggaataggtg aaagtgctca tgttgaggag agattgccgg ccatctgggt atatgaaata
    41281 tgccgagcac tgtccgcttc cccccacccg gctccaggtc gctcgaatta ggttgtctgt
    41341 tggtccggtt gatgtgggat aaagttccaa cccgcaagta gtatgttggc agggactact
    41401 ccgtaatcag accggagttt ttgtttggtg agcaaacacc ttccggaacc gcctgacttg
    41461 tgcgtaatgc tatagcgttt gtcaaatgcc ttcatacatg tggcatgcca gcccagaaat
    41521 agggatgact gtttaggccc ggctaaaccg gtaatgattt gtcgaggtta atctcgtaag
    41581 gcgatattgt cctcaatttc ttggtttcta cgagggcctg gggaacggaa atcttctgaa
    41641 cgggcctcga aagagtcatg gagaaaatta tccgcaagct ttgctttgtt gcaaagttct
    41701 tctgaggccg aagacgcacc acggcaccga caccgcgggc aagcagggtt tctagaactg
    41761 aataggacaa caatcccgtc ttgtttgatc cggggcgacg taatgctagc ggagaatcag
    41821 atggattgat aagatgatca gataaaattt tctcctgcta gtcccgagca agtccacaaa
    41881 ttttactttg ccagaagcac tccacttgag gaagatgtca gagcacagat ccgattggac
    41941 cttcaaagga tctttatcac caggtcttgt catgacttgt atgctttgca gttttgtgtt
    42001 gtgtgcgttc tctttacctc ttacctccga gaacgagcga gagaaaaccg acgggagaag
    42061 aatcgtgcca ttttctcatc tcagcgtggg gctctagcga agcctctggc taagctgaca
    42121 ccacgcacgc tgaagggtag agaaaacgag taaggggacc aaggggcatt ggagggcaga
    42181 tcctcacaca gtcacactcg tgtgtgtggt gtgtgtgtgc tggcgagaca tgttccgaaa
    42241 ctcaaataac ctcttctggt gtcttaatag ctatggttat gtataagtta tgagtaagct
    42301 gtgactagat ccaaaacagg gaagtagttt gcgaaaacac tcataacgtg ggctcggaat
    42361 ccgatcacgt caaaaaggta ggcccccttg gagggctggt tctatgaagg atttggctca
    42421 aactttcaca acgccgttca aggtttcggc ccgtggttaa gtgtcttctt taaacgtact
    42481 ttgaacctcc ccaatcatac tcgctatcat acctccatcg gtcgtccctg gcaggcaggc
    42541 caaagccaga tgggatggga aacatgggaa acccaaatcc ttgccctaat catgaagatg
    42601 caggattact attcttcatc agtattgatt accaaacaga cgacaatctt tggaggcggc
    42661 ctaaatgaag aacccattgt gctggggagc ttgatcccct aaaccttcaa gttcatcccg
    42721 cccccgatcg agttcaccca tcaaatgaca gttcgcgagg ggatc
//
