BGC0000077: hypothemycin biosynthetic gene cluster from Hypomyces subiculosus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 42,765 nt. (total: 42,765 nt).
This entry is originally from NCBI GenBank EU520418.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000077
Short description hypothemycin biosynthetic gene cluster from Hypomyces subiculosus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: EU520418.1
Compounds
  • hypothemycin
Species Hypomyces subiculosus [taxonomy]
References
Chemical products information
hypothemycin
Copy SMILES
C19H22O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACD39760.1
  • Hpm1
2017 - 3848 (-) cytochrome P450
copy AA seq
copy Nt seq
  • ACD39761.1
  • hpm2
4872 - 5661 (+) glutathione-S-transferase
copy AA seq
copy Nt seq
  • ACD39762.1
  • hpm3
6151 - 12661 (-) non-reducing polyketide synthase
copy AA seq
copy Nt seq
  • ACD39763.1
  • hpm4
13801 - 15405 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ACD39764.1
  • hpm5
17106 - 18657 (+) O-methyltransferase
copy AA seq
copy Nt seq
  • ACD39765.1
  • hpm6
19816 - 21579 (+) major facilitator superfamily transporter
copy AA seq
copy Nt seq
  • ACD39766.1
  • hpm7
23947 - 25903 (+) flavin-dependent monooxygenase
copy AA seq
copy Nt seq
  • ACD39767.1
  • hpm8
27565 - 35072 (+) reducing polyketide synthase
copy AA seq
copy Nt seq
  • ACD39768.1
  • hpm9
36050 - 38015 (+) alcohol oxidase
copy AA seq
copy Nt seq
  • ACD39769.1
38330 - 39256 (-) oxidoreductase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.