BGC0000078: incednine biosynthetic gene cluster from Streptomyces sp. ML694-90F3
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Location: 1 - 137,957 nt. (total: 137,957 nt).
This entry is originally from NCBI GenBank AB767280.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000078
Short description incednine biosynthetic gene cluster from Streptomyces sp. ML694-90F3
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB767280.1
Compounds
  • incednine
Species Streptomyces sp. ML694-90F3 [taxonomy]
References
Chemical products information
incednine
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C42H63N3O8
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAP34699.1
 3 - 2069 (+) superfamily I DNA and RNA helicase-like protein
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  • BAP34700.1
 2126 - 2521 (-) hypothetical protein
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  • BAP34701.1
 2644 - 3135 (-) hypothetical protein
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  • BAP34702.1
  • idnA
 3362 - 3583 (-) MbtH-like protein
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  • BAP34703.1
  • idnS1
 4554 - 5216 (+) LmbE family protein
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  • BAP34704.1
  • idnS2
 5408 - 6820 (+) UDP-glucose/GDP-mannose dehydrogenase
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  • BAP34705.1
  • idnS3
 6885 - 7841 (+) NAD-dependent epimerase/dehydratase
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  • BAP34706.1
  • idnR1
 8085 - 10994 (+) LuxR-family transcriptional regulator
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  • BAP34707.1
  • idnL1
 11307 - 12905 (+) AMP-dependent synthetase and ligase
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  • BAP34708.1
  • idnL2
 13073 - 14182 (-) malonyl-CoA-ACP transacylase
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  • BAP34709.1
  • idnL3
 14197 - 15483 (-) (PLP)-dependent aspartate aminotransferase superfamily
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  • BAP34710.1
  • idnL4
 15517 - 16878 (-) radical-SAM L-lysine 2,3-aminomutase
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  • BAP34711.1
  • idnL5
 17000 - 17929 (-) proline iminopeptidase
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  • BAP34712.1
  • idnS4
 18316 - 19644 (+) glycosyltransferase
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  • BAP34713.1
  • idnS5
 19828 - 21036 (-) methyltransferase
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  • BAP34714.1
  • idnS6
 21287 - 22261 (-) dTDP-glucose 4,6-dehydratase
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  • BAP34715.1
  • idnS7
 22258 - 23325 (-) glucose-1-phosphate thymidylyltransferase
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  • BAP34716.1
  • idnS8
 23395 - 24132 (-) N-methyltransferase
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  • BAP34717.1
  • idnL6
 24577 - 24816 (-) acyl carrier protein
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  • BAP34718.1
  • idnL7
 24954 - 26522 (+) AMP-dependent synthetase and ligase
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  • BAP34719.1
  • idnO1
 26677 - 27882 (+) cytochrome P450
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  • BAP34720.1
 28673 - 29308 (+) transcriptional regulator
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  • BAP34721.1
 29779 - 30123 (+) hypothetical protein
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  • BAP34722.1
 30120 - 31583 (+) hypothetical protein
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  • BAP34723.1
 31628 - 32032 (+) hypothetical protein
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  • BAP34724.1
 32138 - 32599 (+) Putative hydrolase
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  • BAP34725.1
 32596 - 32952 (+) hypothetical protein
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  • BAP34726.1
 32960 - 33982 (+) thymidylate synthase
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  • BAP34727.1
 33979 - 35007 (+) nucleoside diphosphate kinase
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  • BAP34728.1
 34997 - 36175 (+) hypothetical protein
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  • BAP34729.1
 36172 - 36774 (+) DNA polymerase III
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  • BAP34730.1
 36768 - 37376 (+) hypothetical protein
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  • BAP34731.1
 37373 - 38023 (+) oxidoreductase
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  • BAP34732.1
 38154 - 38669 (+) hypothetical protein
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  • BAP34733.1
  • idnP1
 39077 - 50023 (-) type I polyketide synthase
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  • BAP34734.1
  • idnP2
 50108 - 66139 (-) type I polyketide synthase
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  • BAP34735.1
  • idnB
 66380 - 67210 (+) thioesterase involved in non-ribosomal peptide biosynthesis
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  • BAP34736.1
  • idnT1
 67450 - 68247 (-) ABC-type multidrug transport system
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  • BAP34737.1
  • idnT2
 68244 - 69200 (-) ABC-type multidrug transport system
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  • BAP34738.1
  • idnR2
 69310 - 70158 (+) regulatory protein TetR
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  • BAP34739.1
  • idnP3
 70616 - 82201 (-) type I polyketide synthase
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  • BAP34740.1
  • idnP4
 82241 - 87412 (-) type I polyketide synthase
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  • BAP34741.1
  • idnS9
 88093 - 89280 (-) glycosyltransferase
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  • BAP34742.1
  • idnS10
 89781 - 91136 (+) NDP-hexose 2,3-dehydratase
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  • BAP34743.1
  • idnS11
 91214 - 92230 (+) NDP-hexose-3-ketoreductase
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  • BAP34744.1
  • idnS12
 92233 - 93567 (+) NDP-hexose-3,4-dehydratase
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  • BAP34745.1
  • idnS13
 93557 - 94852 (+) aminotransferase
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  • BAP34746.1
  • idnS14
 94907 - 96184 (-) glycosyltransferase
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  • BAP34747.1
  • idnO2
 96199 - 97470 (-) cytochrome P450
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  • BAP34748.1
  • idnS15
 97467 - 98396 (-) glycosyltransferase
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  • BAP34749.1
 100768 - 102102 (-) glutamate-1-semialdehyde aminotransferase
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  • BAP34750.1
 102204 - 102950 (+) dehydrogenase
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  • BAP34751.1
 102813 - 103463 (-) hypothetical protein
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  • BAP34752.1
 103460 - 104269 (-) phytanoyl-CoA dioxygenase
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  • BAP34753.1
 106414 - 107517 (-) hypothetical protein
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  • BAP34754.1
 107471 - 108973 (-) hypothetical protein
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  • BAP34755.1
 109004 - 109738 (+) hypothetical protein
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  • BAP34756.1
 109890 - 110147 (-) hypothetical protein
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  • BAP34757.1
 112262 - 112504 (-) hypothetical protein
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  • BAP34758.1
 112454 - 112819 (+) hypothetical protein
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  • BAP34759.1
 113029 - 113415 (+) hypothetical protein
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  • BAP34760.1
 113419 - 114375 (+) hypothetical protein
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  • BAP34761.1
 114372 - 115568 (+) O-methyltransferase
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  • BAP34762.1
 116103 - 116555 (-) secreted protein
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  • BAP34763.1
  • idnP5
 116795 - 128485 (-) type I polyketide synthase
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  • BAP34764.1
  • idnM1
 129343 - 130209 (+) glyceryl-ACP oxidoreductase
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  • BAP34765.1
  • idnM2
 130206 - 130502 (+) acyl carrier protein
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  • BAP34766.1
  • idnM3
 130495 - 131727 (+) acyl-CoA dehydrogenase
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  • BAP34767.1
  • idnM4
 131744 - 132865 (+) FkbH-like protein
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  • BAP34768.1
  • idnM5
 133147 - 133809 (-) O-methyltransferase
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  • BAP34769.1
 134104 - 134511 (+) hypothetical protein
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  • BAP34770.1
 134598 - 136205 (-) spermidine synthase
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  • BAP34771.1
 136213 - 136650 (-) hypothetical protein
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  • BAP34772.1
 136709 - 137125 (-) hypothetical protein
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  • BAP34773.1
 137122 - 137706 (-) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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