BGC0000082: kijanimicin biosynthetic gene cluster from Actinomadura kijaniata
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Location: 1 - 107,627 nt. (total: 107,627 nt).
This entry is originally from NCBI GenBank EU301739.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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Gene details
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000082
Short description kijanimicin biosynthetic gene cluster from Actinomadura kijaniata
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
EU301739.1
via
Compounds
  • kijanimicin
Species Actinomadura kijaniata [taxonomy]
References
Chemical products information
kijanimicin Evidence:
Copy SMILES
C67H100N2O24
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACB46462.1
 3 - 941 (+) fructokinase
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    • KijA1
    • ACB46463.1
    		 1026 - 1850 (-) sugar-O-methyltransferase
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      • KijA2
      • ACB46464.1
      		 1974 - 2954 (-) unknown
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        • KijA3
        • ACB46465.1
        		 3095 - 4273 (-) p450 monooxygenase
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          • KijA4
          • ACB46466.1
          		 4339 - 5619 (-) glycosyltransferase
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            • KijA5
            • ACB46467.1
            		 5920 - 7383 (+) efflux permease
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              • KijA6
              • ACB46468.1
              		 7444 - 7755 (-) heat shock protein GroES
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                • KijA7
                • ACB46469.1
                		 7905 - 9533 (-) heat shock protein GroEL
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                  • KijA8
                  • ACB46470.1
                  		 9904 - 10536 (+) TetR type regulatory protein
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                    • KijS4
                    • ACB46471.1
                    		 10561 - 22326 (-) polyketide synthase
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                      • KijB1
                      • ACB46472.1
                      		 22540 - 23979 (+) sugar 2,3-dehydratase
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                        • KijB2
                        • ACB46473.1
                        		 24021 - 24791 (+) thioesterase
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                          • KijB3
                          • ACB46474.1
                          		 24903 - 26420 (+) FAD-dependent oxidoreductase
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                            • KijC1
                            • ACB46475.1
                            		 26565 - 27770 (+) glycosyltransferase
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                              • KijC2
                              • ACB46476.1
                              		 27782 - 28777 (-) sugar 4-ketoreductase
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                                • KijC3
                                • ACB46477.1
                                		 28839 - 30092 (-) glycosyltransferase
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                                  • KijC4
                                  • ACB46478.1
                                  		 30133 - 31326 (-) glycosyltransferase
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                                    • KijC5
                                    • ACB46479.1
                                    		 31487 - 32086 (+) TetR type regulatory protein
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                                      • KijE
                                      • ACB46480.1
                                      		 32122 - 33975 (-) hydrolase superfamily dihydrolipoamide acyltransferase-like protein
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                                        • KijD
                                        • ACB46481.1
                                        		 33972 - 34199 (-) ACP
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                                          • KijC
                                          • ACB46482.1
                                          		 34196 - 36082 (-) FkbH-like protein
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                                            • KijB
                                            • ACB46483.1
                                            		 36079 - 37107 (-) ketoacyl acylcarrier protein synthase III
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                                              • KijA
                                              • ACB46484.1
                                              		 37164 - 38636 (-) FAD-dependent oxidoreductase
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                                                • KijS5
                                                • ACB46485.1
                                                		 38626 - 43038 (-) polyketide synthase
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                                                  • KijS3
                                                  • ACB46486.1
                                                  		 43118 - 48496 (-) polyketide synthase
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                                                    • KijS2
                                                    • ACB46487.1
                                                    		 48520 - 69138 (-) polyketide synthase
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                                                      • KijS1
                                                      • ACB46488.1
                                                      		 69155 - 87880 (-) polyketide synthase
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                                                        • KijD1
                                                        • ACB46489.1
                                                        		 88509 - 89753 (-) sugar 3-C-methyl transferase
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                                                          • KijD2
                                                          • ACB46490.1
                                                          		 89836 - 90957 (-) sugar 3-aminotransferase
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                                                            • KijD3
                                                            • ACB46491.1
                                                            		 90964 - 92277 (-) FAD-dependent oxidoreductase
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                                                              • KijD4
                                                              • ACB46492.1
                                                              		 92341 - 93369 (-) sugar 4,6-dehydratase
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                                                                • KijD5
                                                                • ACB46493.1
                                                                		 93356 - 94252 (-) sugar nucleotidyltransferase
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                                                                  • KijD6
                                                                  • ACB46494.1
                                                                  		 94372 - 94911 (-) NADPH-dependent flavin reductase
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                                                                    • KijD7
                                                                    • ACB46495.1
                                                                    		 94935 - 96086 (-) sugar 4-aminotransferase
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                                                                      • KijD8
                                                                      • ACB46496.1
                                                                      		 96321 - 97103 (+) SAM-dependent methyltransferase
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                                                                        • KijD9
                                                                        • ACB46497.1
                                                                        		 97138 - 98313 (-) glycosyltransferase
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                                                                          • KijD10
                                                                          • ACB46498.1
                                                                          		 98397 - 99395 (-) sugar 3-ketoreductase
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                                                                            • KijD11
                                                                            • ACB46499.1
                                                                            		 99457 - 100065 (-) sugar 5-epimerase
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                                                                              • KijD12
                                                                              • ACB46500.1
                                                                              		 100109 - 100912 (-) TetR type regulatory protein
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                                                                                • ACB46501.1
                                                                                		 102602 - 103531 (-) D-ala, D-ala carboxypeptidase
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                                                                                  • ACB46502.1
                                                                                  		 103802 - 104389 (+) conserved hypothetical protein
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                                                                                    • ACB46503.1
                                                                                    		 104386 - 105006 (-) permease
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                                                                                      • ACB46504.1
                                                                                      		 105003 - 106403 (-) selenium binding protein
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                                                                                        Biosynthesis information
                                                                                        Annotation changelog

                                                                                        Entry version: 4

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2022-10-07
                                                                                        Update chemical activity to schema version 2.11
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 3

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2022-09-15
                                                                                        Updated bioactivity data
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 2

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2019-10-16
                                                                                        Migrated from v1.4
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 1

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2015-06-12
                                                                                        Submitted
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        Detailed domain annotation
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