Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000085.1:
Cluster 1Polyketide168094

BGC0000085, lankamycin biosynthetic gene cluster from Streptomyces rochei. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: lankamycin
PubChem ID: 122781
SMILES string: Copy to clipboard
Molecular formula: C42H72O16
Average molecular mass: 833.022 Da

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

lankamycin (BGC0000085). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank AB088224, positions 43059-111152. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Mochizuki S et al. (2003) The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism. Mol Microbiol 48(6):1501-10.
2. Hiratsu K et al. (2000) Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei. Mol Gen Genet 263(6):1015-21.
3. Suwa M et al. (2000) Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei. Gene 246(1-2):123-31.
4. Kinashi H et al. (1998) Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs. Biosci Biotechnol Biochem 62(10):1892-7.