Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000092.1:
Cluster 1Polyketide147981

BGC0000092, megalomicin A / megalomicin B / megalomicin C1 / megalomicin C2 biosynthetic gene cluster from Micromonospora megalomicea. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: megalomicin A
PubChem ID: 31864
SMILES string: Copy to clipboard
Molecular formula: C44H80N2O15
Average molecular mass: 877.123 Da

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:
Type I

Gene cluster description

megalomicin A / megalomicin B / megalomicin C1 / megalomicin C2 (BGC0000092). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank AF263245. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Volchegursky Y et al. (2000) Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea. Mol Microbiol 37(4):752-62.