BGC0000096: midecamycin biosynthetic gene cluster from Streptomyces mycarofaciens
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Location: 1 - 84,428 nt. (total: 84,428 nt).
This entry is originally from NCBI GenBank BD420675.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0000096
Short description midecamycin biosynthetic gene cluster from Streptomyces mycarofaciens
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
BD420675.1
via
Compounds
  • midecamycin
Species Streptomyces mycarofaciens [taxonomy]
References
  • [1]
Chemical products information
midecamycin Evidence:
Copy SMILES
C41H67N1O15
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ctg1_orf1
 1 - 675 (+)
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    • ctg1_orf2
    		 1168 - 2202 (+)
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      • ctg1_orf3
      		 2220 - 3182 (+)
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        • ctg1_orf4
        		 3237 - 4691 (+)
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          • ctg1_orf5
          		 4695 - 5948 (+)
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            • ctg1_orf6
            		 6048 - 6629 (+)
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              • ctg1_orf7
              		 6653 - 7858 (+)
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                • ctg1_orf8
                		 8149 - 9015 (+)
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                  • ctg1_orf9
                  		 9012 - 9335 (+)
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                    • ctg1_orf10
                    		 9316 - 10458 (+)
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                      • ctg1_orf11
                      		 10455 - 11603 (+)
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                        • ctg1_orf12
                        		 11729 - 12961 (+)
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                          • ctg1_orf13
                          		 13016 - 14044 (+)
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                            • ctg1_orf14
                            		 14074 - 15096 (+)
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                              • ctg1_orf15
                              		 15490 - 17466 (+)
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                                • ctg1_orf16
                                		 17522 - 18895 (+)
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                                  • ctg1_orf17
                                  		 19063 - 20229 (+)
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                                    • ctg1_orf18
                                    		 20307 - 21743 (+)
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                                      • ctg1_orf19
                                      		 21733 - 22527 (+)
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                                        • ctg1_orf20
                                        		 22534 - 23571 (+)
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                                          • ctg1_orf21
                                          		 23555 - 24463 (+)
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                                            • ctg1_orf22
                                            		 24460 - 25650 (+)
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                                              • ctg1_orf23
                                              		 25647 - 26105 (+)
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                                                • ctg1_orf24
                                                		 26180 - 27391 (+)
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                                                  • ctg1_orf25
                                                  		 27584 - 27724 (+)
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                                                    • ctg1_orf26
                                                    		 27937 - 28983 (+)
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                                                      • ctg1_orf27
                                                      		 29418 - 42779 (+)
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                                                        • ctg1_orf28
                                                        		 42823 - 48657 (+)
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                                                          • ctg1_orf29
                                                          		 48730 - 59802 (+)
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                                                            • ctg1_orf30
                                                            		 59850 - 64556 (+)
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                                                              • ctg1_orf31
                                                              		 64687 - 70365 (+)
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                                                                • ctg1_orf32
                                                                		 70365 - 71078 (+)
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                                                                  • ctg1_orf33
                                                                  		 71113 - 72360 (+)
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                                                                    • ctg1_orf34
                                                                    		 72400 - 73665 (+)
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                                                                      • ctg1_orf35
                                                                      		 73694 - 75043 (+)
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                                                                        • ctg1_orf36
                                                                        		 75899 - 76564 (+)
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                                                                          • ctg1_orf37
                                                                          		 76602 - 77765 (+)
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                                                                            • ctg1_orf38
                                                                            		 78039 - 79313 (+)
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                                                                              • ctg1_orf39
                                                                              		 79391 - 81052 (+)
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                                                                                • ctg1_orf40
                                                                                		 81673 - 82356 (+)
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                                                                                  • ctg1_orf41
                                                                                  		 82453 - 82617 (+)
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                                                                                    • ctg1_orf42
                                                                                    		 82760 - 83362 (+)
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                                                                                      • ctg1_orf43
                                                                                      		 84329 - 84427 (+)
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                                                                                        Biosynthesis information
                                                                                        Annotation changelog

                                                                                        Entry version: 4

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2022-10-07
                                                                                        Update chemical activity to schema version 2.11
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 3

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2022-09-15
                                                                                        Removed empty gene annotations
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        2022-09-15
                                                                                        Updated bioactivity data
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 2

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2019-10-16
                                                                                        Migrated from v1.4
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        2019-10-16
                                                                                        Updated reference publication(s) (MIBiG Annotathon)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 1

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2015-06-12
                                                                                        Submitted
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        Detailed domain annotation
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                                                                                        Modifications to original record
                                                                                        • ctg1_orf1 was added
                                                                                        • ctg1_orf2 was added
                                                                                        • ctg1_orf3 was added
                                                                                        • ctg1_orf4 was added
                                                                                        • ctg1_orf5 was added
                                                                                        • ctg1_orf6 was added
                                                                                        • ctg1_orf7 was added
                                                                                        • ctg1_orf8 was added
                                                                                        • ctg1_orf9 was added
                                                                                        • ctg1_orf10 was added
                                                                                        • ctg1_orf11 was added
                                                                                        • ctg1_orf12 was added
                                                                                        • ctg1_orf13 was added
                                                                                        • ctg1_orf14 was added
                                                                                        • ctg1_orf15 was added
                                                                                        • ctg1_orf16 was added
                                                                                        • ctg1_orf17 was added
                                                                                        • ctg1_orf18 was added
                                                                                        • ctg1_orf19 was added
                                                                                        • ctg1_orf20 was added
                                                                                        • ctg1_orf21 was added
                                                                                        • ctg1_orf22 was added
                                                                                        • ctg1_orf23 was added
                                                                                        • ctg1_orf24 was added
                                                                                        • ctg1_orf25 was added
                                                                                        • ctg1_orf26 was added
                                                                                        • ctg1_orf27 was added
                                                                                        • ctg1_orf28 was added
                                                                                        • ctg1_orf29 was added
                                                                                        • ctg1_orf30 was added
                                                                                        • ctg1_orf31 was added
                                                                                        • ctg1_orf32 was added
                                                                                        • ctg1_orf33 was added
                                                                                        • ctg1_orf34 was added
                                                                                        • ctg1_orf35 was added
                                                                                        • ctg1_orf36 was added
                                                                                        • ctg1_orf37 was added
                                                                                        • ctg1_orf38 was added
                                                                                        • ctg1_orf39 was added
                                                                                        • ctg1_orf40 was added
                                                                                        • ctg1_orf41 was added
                                                                                        • ctg1_orf42 was added
                                                                                        • ctg1_orf43 was added