BGC0000103: mycolactone B biosynthetic gene cluster from Mycobacterium ulcerans Agy99
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Location: 30,054 - 137,271 nt. (total: 107,218 nt).
This entry is originally from NCBI GenBank BX649209.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000103
Short description mycolactone B biosynthetic gene cluster from Mycobacterium ulcerans Agy99
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
BX649209.1
30054 - 137271
via
Compounds
  • mycolactone B
Species Mycobacterium ulcerans Agy99 [taxonomy]
References
Chemical products information
mycolactone B Evidence:
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C44H70O9
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • MUP032c
  • CAE46843.1
  • mlsB
 30054 - 72446 (-) Type I modular polyketide synthase
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    • MUP033c
    • CAE46844.1
    		 72536 - 72910 (-) putative transposase
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      • MUP034c
      • CAE46845.1
      		 73008 - 73547 (-) putative transposase
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        • MUP035
        • CAE46846.1
        		 74138 - 74851 (+) putative transposase
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          • MUP036c
          • CAE46847.1
          		 74905 - 76239 (-) probable transposase for the insertion element IS2606
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            • MUP037
            • CAE46848.1
            		 76556 - 77911 (+) putative transposase
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              • MUP038c
              • CAE46849.1
              		 78019 - 78924 (-) possible thioesterase
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                • MUP039c
                • CAE46850.1
                • mlsA2
                		 79080 - 86312 (-) Type I modular polyketide synthase
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                  • MUP040c
                  • CAE46851.1
                  • mlsA1
                  		 86299 - 137271 (-) Type I modular polyketide synthase
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                    Biosynthesis information
                    Annotation changelog

                    Entry version: 4

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-10-07
                    Update chemical activity to schema version 2.11
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Updated bioactivity data
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2019-10-16
                    Updated compound(s) information (NPAtlas curation)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2015-06-12
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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