BGC0000103: mycolactone B biosynthetic gene cluster from Mycobacterium ulcerans Agy99
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Location: 30,054 - 137,271 nt. (total: 107,218 nt).
This entry is originally from NCBI GenBank BX649209.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000103
Short description mycolactone B biosynthetic gene cluster from Mycobacterium ulcerans Agy99
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: BX649209.1
Compounds
  • mycolactone B
Species Mycobacterium ulcerans Agy99 [taxonomy]
References
Chemical products information
mycolactone B
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C44H70O9
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • MUP032c
  • CAE46843.1
  • mlsB
 30054 - 72446 (-) Type I modular polyketide synthase
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  • MUP033c
  • CAE46844.1
 72536 - 72910 (-) putative transposase
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  • MUP034c
  • CAE46845.1
 73008 - 73547 (-) putative transposase
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  • MUP035
  • CAE46846.1
 74138 - 74851 (+) putative transposase
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  • MUP036c
  • CAE46847.1
 74905 - 76239 (-) probable transposase for the insertion element IS2606
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  • MUP037
  • CAE46848.1
 76556 - 77911 (+) putative transposase
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  • MUP038c
  • CAE46849.1
 78019 - 78924 (-) possible thioesterase
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  • MUP039c
  • CAE46850.1
  • mlsA2
 79080 - 86312 (-) Type I modular polyketide synthase
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  • MUP040c
  • CAE46851.1
  • mlsA1
 86299 - 137271 (-) Type I modular polyketide synthase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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