LOCUS       BGC0000104             25486 bp    DNA     linear   PLN 12-NOV-2014
DEFINITION  Penicillium brevicompactum mycophenolic acid biosynthesis gene
            cluster, complete sequence.
ACCESSION   BGC0000104
VERSION     BGC0000104
KEYWORDS    .
SOURCE      Penicillium brevicompactum
  ORGANISM  Penicillium brevicompactum
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Penicillium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 12:50:42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 6999
            Orig. end    :: 32485
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..25486
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     gene            complement(<1..>1137)
                     /gene="mpaA"
     mRNA            complement(join(<1..595,669..915,1032..>1137))
                     /gene="mpaA"
                     /product="putative prenyl transferase"
     CDS             complement(join(1..595,669..915,1032..1137))
                     /codon_start=1
                     /gene="mpaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /note="MpaA"
                     /product="putative prenyl transferase"
                     /protein_id="ADY00128.1"
                     /sec_met_domain="ubiA (E-value: 3.5e-17, bitscore: 51.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNAVEDSGPRDLLFLLISTSRFNRYMPYYTMMAAESLSIEFILY
                     KAGLCFVHCLLLCGAGNTWNDLVDRDIDARVARTKMRPLASGKVTLTEALLWMTGQYFL
                     SVKMLDLILDGRNIWSLMLPLTASIMLYPYLKRPIFSKVFVYPQYILGLAIGYPAITGW
                     ASITGSEEPLGDIIKHCIPICLLVFFWCVYFNTAYSHQDSVDDRKMNINSAYVIAGQRI
                     RLFLAFLSVLPLLTIPYIISTINSPWLWVSWMATWTVSIIMQIAQFDSQKLESGGRIHW
                     DNFLLGLWTIAACMVEVGLQKVEFWKNVEGYIKL"
     misc_feature    1..25486
                     /note="mycophenolic acid biosynthesis gene cluster"
     region          1..25486
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            <2644..>4120
                     /gene="mpaB"
     mRNA            join(<2644..2928,3027..3521,3669..3955,4009..>4120)
                     /gene="mpaB"
                     /product="MpaB"
     CDS             join(2644..2928,3027..3521,3669..3955,4009..4120)
                     /codon_start=1
                     /gene="mpaB"
                     /product="MpaB"
                     /protein_id="ADY00129.1"
                     /transl_table=11
                     /translation="MSLPLPPALSELARALPYSRTQWLPIFVGFLIGYPILIRALRYKR
                     HGEMKKKFYFPTRESMAEMTDEEAFLIQKEMAQLEFPFMFLTSGQFALFRTYGIPTISH
                     LLTKTGQFSKPETSFKRYTDTAALIGEMVENSPTSQRAFISVARTRFLHSGYQASGKIL
                     DADLLYTLALFAVQPVRFIENFEWRTLSDLELCAIGTFWKSLGDALGISSEILPSGKTG
                     FKDGIQWLEEVDVWSQDYEAKYMVPDPKNRESADQATAMLISNRYEAPTPGWSMVFSTL
                     LAIRKLILRYLSPPRPAALAVSNIAQKPDKDDRYHRMSWDALPFYIRPTFWNRWGPMAW
                     ISWLMGHPVPGDLGQKKGPQGDPGNDEGIKDLKDGEMSLPLVWSKYHATTND"
     gene            complement(<4536..>12280)
                     /gene="mpaC"
     mRNA            complement(join(<4536..5461,5536..9972,10038..10413,
                     10472..11504,11706..>12280))
                     /gene="mpaC"
                     /product="polyketide synthase"
     CDS             complement(join(4536..5461,5536..9972,10038..10413,
                     10472..11504,11706..12280))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (361-776). E-value:
                     6.7e-152. Score: 498.1. Matches aSDomain:
                     nrpspksdomains_mpaC_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (885-1175). E-value: 1e-51.
                     Score: 167.9. Matches aSDomain:
                     nrpspksdomains_mpaC_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (1288-1440). E-value: 3.2e-15.
                     Score: 48.7. Matches aSDomain:
                     nrpspksdomains_mpaC_PKS_DH.1"
                     /NRPS_PKS="Domain: PP-binding (1614-1680). E-value:
                     9.7e-15. Score: 46.8. Matches aSDomain:
                     nrpspksdomains_mpaC_PP-binding.1"
                     /NRPS_PKS="Domain: cMT (1910-2073). E-value: 5e-65. Score:
                     211.1. Matches aSDomain: nrpspksdomains_mpaC_cMT.1"
                     /codon_start=1
                     /function="catalyzing the synthesis of 5-methyl orsellinic
                     acid, first step of mycophenolic acid biosynthesis"
                     /gene="mpaC"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 93.6; E-value:
                     1.8e-28)"
                     /gene_kind="biosynthetic"
                     /note="MpaC"
                     /product="polyketide synthase"
                     /protein_id="ADY00130.1"
                     /sec_met_domain="PKS_KS (E-value: 9.5e-153, bitscore:
                     498.1, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-52, bitscore: 167.9,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-15, bitscore:
                     46.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.3e-09, bitscore:
                     26.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFHKGQPKEDLRVLFGPQCPDITDSITHIRDAISKDPTGLGFLT
                     NILDELPSLWPTIAGAWPALKNVEGESQLLALGRLFEHESEDRVEASNLMMTPITVMRH
                     IVDFWNLQDVATHPAFPSSSLSETEMPRIVDTQGFCVGLLAAIAVACSRNTQEFQYVAS
                     NAIRLSLCVGALVDLDEILCGSTTSLAVSAERVKQEIHDHGLRTKQLSLRGRFHHEAHR
                     EGIQHIMKLCTNDSRFKLPRSDALLTPLRSSQGGEIFQQEALLHTVALDSILCAKANWY
                     DVVSALINSTEMTVDQSHLLSIGPEEFVPRSARSRSVARRELQSYAMQGFSNESPQPST
                     ASLSNSVQTFDSRPQAAEASPIAITGMACRYPNADTLAQLWDLLELGRCTVKSPPESRF
                     HMSDLQREPKGPFWGHFLERPDVFDHRFFNISAREAESMDPQQRVALQVAYEAMESAGY
                     LGWQPNGLSRDIGCYVGVGSEDYTENVASRNANAFSITGTLQSFIAGRISHHFGWSGPS
                     ISLDTACSSAAVAIHLACKALQTNDCKIALAGGVNVLTNPRVYQNLSAASFLSPSGACK
                     PFDASADGYCRGEGAGLFVLRPLQDAIDNGDPILGVIAGSAVNQGSNNSPITVPDAEAQ
                     RSLYNKAMSLAGVSPDEVTYVEAHGTGTQVGDPIELDSLRRTFGGPQRRNSLHIGSIKG
                     NIGHTETSSGAAGLLKTILMLQQQRIPRQANFNQLNPKVKSLTPDRLVIASESTEWAST
                     ERVAMVSNYGASGSNAALIVKEHAPIRSEQNGTAPEYIQNVPILVSARSEESLRAYCGA
                     LRATLLSHPPSETLVQKLAYNLAMKQNRDLPLNLTFSTSSDATSLSARLEAISTGASAD
                     LIQKRPSNEPPVVLCFGGQNGLTATISKEVFDASALLRTHLEDCEEVGRTLGLPSLFPT
                     IFSSAPITNIIHLHFILFSIQYASAKAWLDSGLRVSRIVGHSFGQLTALSVAGSLSVRD
                     GIHLVTERARLIESSWGPESGIMLAVEGTDIEVQQLLDQTGHIADVACYNGPRQQVLAG
                     TAESIAAIENAAARTPSASKLRLTRLQNSHAFHSRLVDSIVPAIMEVAGSLVYQTPIIP
                     IEACSASGDWSTITAAEIVEHSRMPVYFRRAVERVAEKLQAPAVWLEAGSASPIIPMVR
                     RVLESSSVANTYHKIDLGGSSGAQNLANVTSALWAQGVHVQFWPFDRAQHGSFKWMNLP
                     PYQFAQNSHWVDFDPAAFSSAGPSSGKQSAGQEAGLLCQLSESPDERLYHVNIQDALYR
                     ACTQGHAVLNQTLCPASMYMEMVLRAAASIFPTGNASEPAMSHIEDLTISSPLVLDPQG
                     DVFLRLTSDGAGPTRPWLFSIFSSESNDHTSVHAEGTVCLHQERSRALARFQSMDRLLD
                     SARSKTIEADPASNGLKGSTVYAALESVTNYGDYFRGVKKVFANGREASGLVSMMPSAS
                     ETNCDPILLDNFLQVAGIHVNCLSDRRSSEVFVCNAIGETFVINSLLKQKNGASPSTWK
                     VYTSYVRPSKTEIACDIYVMDCQTDTLSAAMMGVRFTSVSIRSLTRALAKLNNNVLETA
                     EAQSVVEPAIPAEKSVVTATPSAPAADGGGAKDLATVQEMLCELFGVSVAEVSPSVSLV
                     DIGVDSLMSTEVLSEIKKRFQVDMSYTTLVDIPNIQGLVEHIFPGHSHAAPSQPVVETA
                     PVQSVAPQAVSHVPTPANNGPPLVSVARQCFDTTHAAVSHTSDAHWTGFFHTTYPKQMT
                     LLTAYILEAFRALGSPLEASEPNEVLIPISVLPRHEQLRKHLYKILESVGLVRQMPTGE
                     LVRTTTPIPLSQSHDLHTQIRAEYPPYALEHDLLQITAPRLADCLTGKADGVSLIFQDA
                     NTRRLVGDVYAQSPVFKSGNLYLARYLLDVVQSFGSSRTIKILEIGAGTGGTTKNLLEK
                     LSTIPGLSTRLEYTFTDISPSLVAAGRKTFANYNFMRYETLNVENDPPSALSGQYDIVL
                     STNCVHATRNLRESCTNIRKLLRPDGILCLVELTRDIFWLDLVFGLLEGWWRFEDGREH
                     ALATEMMWDQTLRQSGFEWVDWTNNETVESNALRVIVASPTGNSSTATMSPSKLTKMET
                     VVWGERDNLQLRADIYYPETVDTTRKQRPIALMIHGGGHVMLSRKDIRPAQTQTLLDAG
                     FLPVSIDYRLCPEVSLAEGPMADARDALSWVRRVLPNIPLLRADIRPDGNQVVAIGWST
                     GGHLAMTLPFTAPAAGISAPNAVLAFYCPTNYEDPFWSNPNFPFGQTVASNEMEYDVWE
                     GLQSMPIAGYNPALKERPLGGWMSTRDPRSRIALHMNWTGQTLPVLLKACTIKGNTEKC
                     SPDDLSRPTEEEIQAVSPNYQIRVGRYNTPTFLIHGTSDDLVPCAQTESTHGALTASGV
                     EAELRVVQEAAHLFDLYPASHAGQEAKAAVAEGYEFLRRHVQL"
     aSDomain        complement(5738..6226)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mpaC_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="5.00E-65"
                     /label="mpaC_cMT.1"
                     /locus_tag="mpaC"
                     /protein_end="2073"
                     /protein_start="1910"
                     /score="211.1"
                     /tool="antismash"
                     /translation="SRTIKILEIGAGTGGTTKNLLEKLSTIPGLSTRLEYTFTDISPSL
                     VAAGRKTFANYNFMRYETLNVENDPPSALSGQYDIVLSTNCVHATRNLRESCTNIRKLL
                     RPDGILCLVELTRDIFWLDLVFGLLEGWWRFEDGREHALATEMMWDQTLRQSGFEWVDW
                     "
     aSDomain        complement(6917..7114)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mpaC_PP-binding.1"
                     /evalue="9.70E-15"
                     /label="mpaC_PP-binding.1"
                     /locus_tag="mpaC"
                     /protein_end="1680"
                     /protein_start="1614"
                     /score="46.8"
                     /tool="antismash"
                     /translation="TVQEMLCELFGVSVAEVSPSVSLVDIGVDSLMSTEVLSEIKKRFQ
                     VDMSYTTLVDIPNIQGLVEHI"
     aSModule        complement(6917..10996)
                     /complete
                     /domains="nrpspksdomains_mpaC_PKS_KS.1"
                     /domains="nrpspksdomains_mpaC_PKS_AT.1"
                     /domains="nrpspksdomains_mpaC_PKS_DH.1"
                     /domains="nrpspksdomains_mpaC_PP-binding.1"
                     /iterative
                     /locus_tags="mpaC"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(7637..8092)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mpaC_PKS_DH.1"
                     /evalue="3.20E-15"
                     /label="mpaC_PKS_DH.1"
                     /locus_tag="mpaC"
                     /protein_end="1440"
                     /protein_start="1288"
                     /score="48.7"
                     /tool="antismash"
                     /translation="GHAVLNQTLCPASMYMEMVLRAAASIFPTGNASEPAMSHIEDLTI
                     SSPLVLDPQGDVFLRLTSDGAGPTRPWLFSIFSSESNDHTSVHAEGTVCLHQERSRALA
                     RFQSMDRLLDSARSKTIEADPASNGLKGSTVYAALESVTNYGDYFRGV"
     aSDomain        complement(8432..9301)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mpaC_PKS_AT.1"
                     /evalue="1.00E-51"
                     /label="mpaC_PKS_AT.1"
                     /locus_tag="mpaC"
                     /protein_end="1175"
                     /protein_start="885"
                     /score="167.9"
                     /tool="antismash"
                     /translation="CFGGQNGLTATISKEVFDASALLRTHLEDCEEVGRTLGLPSLFPT
                     IFSSAPITNIIHLHFILFSIQYASAKAWLDSGLRVSRIVGHSFGQLTALSVAGSLSVRD
                     GIHLVTERARLIESSWGPESGIMLAVEGTDIEVQQLLDQTGHIADVACYNGPRQQVLAG
                     TAESIAAIENAAARTPSASKLRLTRLQNSHAFHSRLVDSIVPAIMEVAGSLVYQTPIIP
                     IEACSASGDWSTITAAEIVEHSRMPVYFRRAVERVAEKLQAPAVWLEAGSASPIIPMVR
                     RVLESSSVA"
     CDS_motif       complement(8954..9055)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mpaC_0004"
                     /evalue="1.10E-11"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="mpaC"
                     /protein_end="1001"
                     /protein_start="967"
                     /score="36.7"
                     /tool="antismash"
                     /translation="IVGHSFGQLTALSVAGSLSVRDGIHLVTERARLI"
     aSDomain        complement(join(9629..9972,10038..10413,10472..10996))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mpaC_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="6.70E-152"
                     /label="mpaC_PKS_KS.1"
                     /locus_tag="mpaC"
                     /protein_end="776"
                     /protein_start="361"
                     /score="498.1"
                     /tool="antismash"
                     /translation="IAITGMACRYPNADTLAQLWDLLELGRCTVKSPPESRFHMSDLQR
                     EPKGPFWGHFLERPDVFDHRFFNISAREAESMDPQQRVALQVAYEAMESAGYLGWQPNG
                     LSRDIGCYVGVGSEDYTENVASRNANAFSITGTLQSFIAGRISHHFGWSGPSISLDTAC
                     SSAAVAIHLACKALQTNDCKIALAGGVNVLTNPRVYQNLSAASFLSPSGACKPFDASAD
                     GYCRGEGAGLFVLRPLQDAIDNGDPILGVIAGSAVNQGSNNSPITVPDAEAQRSLYNKA
                     MSLAGVSPDEVTYVEAHGTGTQVGDPIELDSLRRTFGGPQRRNSLHIGSIKGNIGHTET
                     SSGAAGLLKTILMLQQQRIPRQANFNQLNPKVKSLTPDRLVIASESTEWASTERVAMVS
                     NYGASGSNAALIVKEH"
     CDS_motif       complement(join(9947..9972,10038..10059))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mpaC_0003"
                     /evalue="6.30E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="mpaC"
                     /protein_end="670"
                     /protein_start="654"
                     /score="14.7"
                     /tool="antismash"
                     /translation="YVEAHGTGTQVGDPIE"
     CDS_motif       complement(10252..10290)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mpaC_0002"
                     /evalue="4.50E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="mpaC"
                     /protein_end="590"
                     /protein_start="577"
                     /score="16.2"
                     /tool="antismash"
                     /translation="FDASADGYCRGEG"
     CDS_motif       complement(10490..10537)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mpaC_0001"
                     /evalue="1.40E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="mpaC"
                     /protein_end="530"
                     /protein_start="514"
                     /score="14.2"
                     /tool="antismash"
                     /translation="GPSISLDTACSSAAVA"
     gene            <15779..>17180
                     /gene="mpaD"
     mRNA            join(<15779..16345,16494..16618,16682..>17180)
                     /gene="mpaD"
                     /product="putative P450 monooxygenase"
     CDS             join(15779..16345,16494..16618,16682..17180)
                     /codon_start=1
                     /gene="mpaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 177.9; E-value: 5.8e-54)"
                     /gene_kind="biosynthetic-additional"
                     /note="MpaD"
                     /product="putative P450 monooxygenase"
                     /protein_id="ADY00131.1"
                     /sec_met_domain="p450 (E-value: 8.6e-31, bitscore: 96.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFIVTCMPCMALSFDLDQTWFQSLILVLYRPSTQVDLDSRRSVI
                     AIHCSPNLHTTGSHLLTLRFQGDFYRTQKPYTRNKGAMPAVFNTQDEDLHKQLRSPIAS
                     LYSMTNVVRLEPLVDETLTVLSKQLDERFVGTNDKPFDLGDWLQYFAFDSMGTLTFSRR
                     YGFLEQGRDMHGILQEIWNFMTRVAVVVDNFISQRVSSRENDEKADEKDMLSQFLDIQA
                     SNPHSIMPWAPRAWTFSNVMAGSDSTANVMRTMMYNLLVDRDTLRSLRAELLEAENSNG
                     LSRSLPSWDGVRSLPYLDACVLEALRLHPPFCLPFERVVPEGGITVCETYLPAGTVVGI
                     SPYLANRDKQTFGDDADKWRPSRWLDLSREDRVKLENSILTVSRSFDYVKDALADV"
     gene            <17740..>18525
                     /gene="mpaE"
     mRNA            <17740..>18525
                     /gene="mpaE"
                     /product="putative metallo-beta-lactamase superfamily II
                     enzyme"
     CDS             17740..18525
                     /codon_start=1
                     /gene="mpaE"
                     /note="MpaE"
                     /product="putative metallo-beta-lactamase superfamily II
                     enzyme"
                     /protein_id="ADY00132.1"
                     /transl_table=11
                     /translation="MIKSQTVIQEPRNISDVLDSDESSLGVRSKDIEAIIWSHAHFDHI
                     GDPSTFPPSTELVVGPGIRDTHWPGFPTNPDAINLNTDIQGRNVREISFEKTQKGATKI
                     GSFDAVDYFGDGSFYLLDAAGHSVGHIGALARVTTSPVSFVFMGGDSCHHAGVLRPTKY
                     LPCPLDSGDTSLPCKSDSVFTLSPALPTDYTAALRTVENIKELDACEDVFVVLAHDATL
                     KGKVDFYPSKINDWKAKEYGKKTKWLFYKDIENSIEGQK"
     gene            complement(<18958..>20657)
                     /gene="mpaF"
     mRNA            complement(join(<18958..20084,20148..20456,20510..>20657))
                     /gene="mpaF"
                     /product="putative inosine monophosphate dehydrogenase"
     CDS             complement(join(18958..20084,20148..20456,20510..20657))
                     /codon_start=1
                     /function="confers resistance against mycophenolic acid"
                     /gene="mpaF"
                     /note="MpaF; IMPDH"
                     /product="putative inosine monophosphate dehydrogenase"
                     /protein_id="ADY00133.1"
                     /transl_table=11
                     /translation="MVEILDYTKALEVLKEYPSGDGLHVDTLLDSDNHGALTYNDFLIL
                     PGSITFSAADVSLDTKVTRRFTIKAPLLSSPMDTVTEHNMAIHMALLGGLGVIHNNCPP
                     DDQAEMVRKVKRYENGFILDPVVLSPSTTVAEAKELKTKWNFGGFPVTEKGTLHSKLLG
                     IVTSRDIQFHKTPEDPVTAVMSTDLVTAPAGTTLAEANEVLRSSKKGKLPIVDKDGLLV
                     SLLSRSDLMKNIHYPLASKLPSKQLLCAAAISTHDADKVRLQKLVDAGLDIVVVDSSQG
                     NSMYQIAMIKWIKSTFPDIDIIAGNIVTREQAAALIAAGADGLRIGMGSGSACITQEVM
                     AVGRPQAASVRSVSAFAARFGVPTIADGGVQNLGHIVKGLALGASAVMMGSLLAGTTES
                     PGEYYVSNEGQLVKAFRGMGSIAVMEDKGKSGGGKNAGASRYFSENDKVKVAQGVAGSV
                     VDRGSITQYVPYLVAGIQHSLQDIGVQDLEALHTGVNNGQVRFEMRSASAQTEGNVHGL
                     HSHEKKLYSS"
     gene            complement(<21275..>22523)
                     /gene="mpaG"
     mRNA            complement(join(<21275..22303,22356..>22523))
                     /gene="mpaG"
                     /product="putative O-methyltransferase"
     CDS             complement(join(21275..22303,22356..22523))
                     /codon_start=1
                     /gene="mpaG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 163.8; E-value:
                     1e-49)"
                     /gene_kind="biosynthetic-additional"
                     /note="MpaG"
                     /product="putative O-methyltransferase"
                     /protein_id="ADY00134.1"
                     /transl_table=11
                     /translation="MSAASPASIIQELASAAKQYENNESGAREALIAQSRALIASLEVP
                     SEFIQHTFWSQPALSAIVRLATDVNLFQYLKDAQEEGLSAEALASKTGMDVSLFARLAR
                     HLVAMNVITSRNGVFYGTALSNGLAAENYQQSIRFCHDVSRPSFGAFPSFFKGNGYKTP
                     ALGTTDGPFQSAHKVDISFPQWLVGNPPYLQYFNSYMSAYRAGKPNWCDNGFYPVADRL
                     LNGFDASVSDVLLVDVGGGRGHDIATFGSQFSPLPGRLVLQDREQVINSIPADESRQFE
                     ATTHDIFTTQPVKNARAYYMHSVPHGFGDEDAVKIMANLVPALAKGYSRVLLNEIVVDE
                     ESPVMSATNMDLIMLAHMGAKERTEADWRSILTRAGLKVVNIYSYPGVAESLIEAELA"
     gene            complement(<24006..>25486)
                     /gene="mpaH"
     mRNA            complement(join(<24006..24873,24945..25053,25107..25239,
                     25295..>25486))
                     /gene="mpaH"
                     /product="putative hydrolase"
     CDS             complement(join(24006..24873,24945..25053,25107..25239,
                     25295..25486))
                     /codon_start=1
                     /gene="mpaH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /note="MpaH"
                     /product="putative hydrolase"
                     /protein_id="ADY00135.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.5e-11, bitscore:
                     33.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEKFTITEHLVPGSHIREYPGSTVNQQDVLKIHVKNYTPKREG
                     PVPDDAITFIATHGVGLPKELYEPLWDELLDQASGFHIRAIWMADVASMNQSGIHNEDK
                     LSMDCSWMDHARDLLLMINHFRDQMPRPLVGIGHSFGGNIITNLAYLHPRLFTTLLLLD
                     PLIQLSPPSLGFGTDAPSAINYTLWRDDVWPSREEAIRANRAIMQGMDPRCLDRMTKHF
                     FRDLPTPLYPDVEAIKARFGTTADSTTTPVTLTTPKYHELVAQIRQNFNARDPKTGRIE
                     VPRDTHADMDPLVAYIPLYRPEPRSTFRRLETLRPSCLWVIAGATFLNIDEIREGVKIC
                     GSGIGGSGGVPDGRVREVVLPGFGHLMPFQEVKTVAGTCVVWLQQEMDRFRQTERQWKE
                     DRDGKSHQAVEENWYKVLKPIPTGRKKRSDKGKL"
ORIGIN
        1 tcaaagctta atgtaaccct caacattctt ccagaattcc accttctgca atccgacttc
       61 aaccatgcaa gcagcgatcg tccacaatcc cagcaggaag ttgtcccaat ggatacgacc
      121 gccactttca agcttctgcg aatcaaactg agcaatctgc atgatgatgg aaacagtcca
      181 ggtagccatc caggagaccc acaaccacgg cgagttgatg gtagagatga tgtatggaat
      241 tgtaagaagt ggcagaacac tcaaaaaggc aaggaacagt cgaatgcgct gacctgcaat
      301 gacgtaggca gagttgatgt tcatcttccg gtcatcgacg ctatcttggt ggctgtatgc
      361 ggtgttgaag tacacacacc agaagaagac aaggaggcag attgggatgc aatgcttgat
      421 gatgtcacca aggggctcct cgctgccggt gatcgaagcc caccctgtga tggcggggta
      481 accaatagca agacccagga tatattgggg gtaaacgaag accttgctga agatgggtcg
      541 cttcaggtag gggtaaagca tgatgctggc ggtcaatggc agcatgaggc tccagctaag
      601 agaaaaacag tttagtatat cttgggtctc tggtatcgga gttgtagagt cttcctgacg
      661 agacttacat gtttcgtcca tccaaaatga gatccagcat tttgacggac aggaaatatt
      721 gaccggtcat ccaaagaagt gcctcagtca gagtgacctt tccagatgcc aaaggccgca
      781 tctttgtgcg tgccactctg gcgtcaatat cgcgatccac aagatcgttc catgtgtttc
      841 cggcaccgca aagcagcaga cagtggacga aacagagacc ggccttgtac aaaatgaact
      901 cgatcgagag gctttctgga tcctgttgta atttgagagc gccggcgatt aaagtggccc
      961 atactatttt gctcaaaaag ctccacgtta ctcattgctt taaagctagc aggaataggg
     1021 acatatctta ccagcagcca tcatagtgta gtacggcatg taccgattga atcgcgaggt
     1081 actgatcagt aggaacagca ggtcccgagg accagagtcc tccactgcgt tggtcatgtt
     1141 gagagtgagg cagtgaaata tgacgccaaa aggatacaga aaatcacgaa gtggcaggac
     1201 tggaaagctt tccaagattc tgctgtggat ataggaaatt tttcttcttg aaagcccctc
     1261 aaagtattca aagaacccac gagaactttg accgtggtgg gaattcggta gtgctcaggt
     1321 cagattgtat acatggcccc tcactctaaa acttccagac cccacgttcc taaacccacc
     1381 cgtagtcagc gtacgaagta aatgacgatc cgatagctgt acaaggctcc cgggaagctc
     1441 atgcaggcga ccagcgactc gtgatacaga cggcagacaa ccgagacaac gcagatgcac
     1501 acctacggat acggaatgct ccatctgacc acagagagag ccacagtctc accgaaagcc
     1561 ttgtcatggc tgaattgcct cttcggggcc aacgtgattc acccaattga ggtgaccgct
     1621 acgtgtgtat caaacgaaaa aggatgaata ggcattcccg cctgtttcat tacccagccg
     1681 ttctgagtat aagattctct atacttgtat gaccccaaag tacagagtat tacggagtat
     1741 gcaaggaggt gtcttcgatg gagtgtgaat atttgtatta aagcattaca caaatcggta
     1801 aaatatttcg gacccaccgc ggacgccggg ccggatgggg gccaagcgcg ggatcctccc
     1861 gagctgctta cgccccagcc ttggaattgg tgcagaaaaa cagggtttct cccgagaaaa
     1921 cactctaaga ccgtcctgca atgctgaata cctgtatttg taaaaccaat acacacaacc
     1981 tccatcaagc tcgcatgatt caaaccctaa ttgacgccaa tggtcttgat gttacatccc
     2041 ggtcagtacg agggacgttg tatgcatgtc cgaggtatac gagtcccacc cgtaaagtat
     2101 tcggacatat ttaggtcccc gagatccgac agccattgtt ctttttcgcc tcgcacccat
     2161 tttccgtttt gaggtttatg caagagttta tatccagccg attattgagt gttgtaaaat
     2221 acgatcgagt tttctttagc ttttctcttt ttttttttct ttgtcttttt ctttttcttt
     2281 ttcttctgtt tgtttttttc tgtttttctc ggccccaccc cgtaacgcct ctgcatccac
     2341 gttcttcaat accaactaaa tatctaatgt aacagactgc atagtaggcc ccccaaaaca
     2401 gctcagagtc aagtggcaaa gataccttag gaaattcagg ctccctgtct ccgctctacg
     2461 ctcacgtaca ttcattttac tgcagtactt gcattgtggt ccattgagtc gttgcatatt
     2521 aataaacggc aaaaacagcc gacacaagca gagccgaggc cagcaatcac tcaatcgttc
     2581 aaatttccat cgatcgtttg agatagctct ctaagacata acgtccaagt tatgaatagc
     2641 agcatgtctt tgcctttgcc tccagcactt tctgagcttg cgagggcact tccctacagc
     2701 agaactcaat ggcttccaat cttcgtggga tttctgattg ggtaccccat ccttatcagg
     2761 gcattgcgtt ataagcgaca tggagagatg aagaagaaat tctatttccc aactcgcgag
     2821 tccatggctg aaatgaccga tgaggaggca ttcctgattc aaaaggaaat ggcacagctc
     2881 gagttcccat tcatgttctt gacatctggg cagtttgcac tattccgggt atgcagttca
     2941 atttcattaa ttatatagtt ctatatatga aagccacacg gacacctttg cttgaacttg
     3001 atttatcttt ttctaatcat ttacagacat atggcattcc gacaatctct catcttctaa
     3061 cgaaaaccgg gcaattctcc aagccagaaa catccttcaa acgctataca gacacagctg
     3121 ctctgattgg tgaaatggta gagaatagtc ctacctcgca gagggcattc atctcagtag
     3181 cccgcacacg attcctacat agcggctatc aagcttcggg caagatcctc gatgctgatt
     3241 tgctttacac ccttgcactc tttgcggtcc agcctgtgcg atttattgag aatttcgaat
     3301 ggcggaccct gagtgatttg gaactctgtg ccattgggac cttttggaag agtctaggtg
     3361 atgctttggg tattagctct gagattcttc catcgggcaa gacaggcttc aaagatggta
     3421 tccaatggct tgaagaggtg gatgtttgga gtcaggatta tgaggccaag tacatggtcc
     3481 cagatcccaa gaatcgcgag tcggcagatc aagcgacggc agttctactt tacaatctgc
     3541 caaaattttt gcatccaata ggactgcaat ttacatctta tatgatggat gatcggctga
     3601 ggaaggcgat gctgtatgtg atatgagtcc actcgagatc ttgaaacttg gctctcacga
     3661 gatcaaagat gctaatttcg aacagatatg aagccccaac tcctggctgg agcatggttt
     3721 tctcaaccct cttggctatt cgcaagttga ttctgcgtta cctatcacca ccacggcctg
     3781 cggctcttgc ggtgtcaaac atagctcaaa agcccgacaa agatgatcgc tatcaccgca
     3841 tgtcttggga tgcactccca ttttacatca ggcctacttt ctggaacaga tggggtccaa
     3901 tggcgtggat ctcttggttg atgggccacc ctgtcccagg cgatcttggc cagaagtact
     3961 atccacaggg atatcatata caagatattg gaccaaaata ctttgaagga aagggccaca
     4021 aggagatcca ggaaatgatg aaggaattaa agatctcaag gacggggaaa tgtcccttcc
     4081 attagtctgg agcaagtacc atgctacaac aaatgattaa aaaaagcatt agtttgggct
     4141 tctgagatta cctgctattt tgacactggg agagaataag atattgcgca agggaatgaa
     4201 acgaaaaaat ggattcacaa acccatggac acacgtaggc aatgagtatc gcagcacgac
     4261 tatatagtaa tggatgttgg aaatggcgag tttcctcacc ttcgcccacc taaccgagct
     4321 cagtgcgtag gaatttcggc cctagattaa ccagtctcag atcgccaccc atgcctgctt
     4381 aattccggca aatcacccct gtgcggagtt tcggccttga atcattaccg cgggctactg
     4441 tagatcttta cagtcaggga gtttgtgtcg acttcaattt gcaatttgga agctcgaaga
     4501 aatatgtgaa aatatacaca gactgaatct aacatctaaa gctgaacatg tcttctcaag
     4561 aactcatatc cttccgccac tgcggccttc gcttcctggc cagcgtgtga ggctgggtaa
     4621 aggtcgaaaa ggtgtgcagc ttcctgcacc actctaagct ccgcctcgac tccgctggcc
     4681 gtcaatgcac catgcgtgga ctccgtttga gcacaaggaa caaggtcatc acttgttcca
     4741 tgaatcaaga atgtcggcgt gttgtagcga ccgacgcgga tctgataatt gggactgact
     4801 gcctgaatct cctcctctgt cggacgagat aggtcatcgg ggctgcattt ctcggtgtta
     4861 cccttgattg tgcatgcctt taacagaaca ggcaaggttt gtccagtcca gttcatgtgc
     4921 agtgcgatcc gactgcgcgg atctctcgtt gacatccagc ccccgagagg gcgttccttg
     4981 agtgcagggt tgtagccggc tatcggcatg ctctgcaatc cttcccaaac atcgtactcc
     5041 atctcgttcg atgcgactgt ctgcccgaag gggaaatttg ggttcgacca gaatggatcc
     5101 tcgtagttgg tcgggcagta gaatgccaag acggcgtttg gagctgaaat accagcagct
     5161 ggggccgtga aaggtagcgt catggcgaga tgaccaccag tagaccatcc gatagccacg
     5221 acctggttcc cgtcgggtcg aatatctgcg cgcagcaagg gaatattcgg gaggacgcgg
     5281 cgaacccagg acagagcgtc gcgggcatcg gccattgggc cttctgctag tgaaacttct
     5341 gggcacaagc ggtagtcgat gctaacaggc aggaagccgg catccagaag ggtctgagtc
     5401 tgggctggac ggatgtcctt gcgagatagc atgacgtggc cacctccgtg gatcatcagg
     5461 gctgagttaa agtgttagta tacaagtggg gcatgaaagc ttgctatggg agaccaaaaa
     5521 taggcatgta cttaccaatc ggtcgctgct tccgagtagt gtccacggtc tcgggatagt
     5581 agatgtctgc acggagctgc agattgtctc gctcacccca aaccacggtt tccatctttg
     5641 tgagtttcga tggagacatt gtcgcggtgg atgagtttcc tgtcggcgaa gcgacaatga
     5701 cacgcagagc atttgactct acggtctcat tgtttgtcca gtcaacccac tcaaatccag
     5761 attgacgaag agtctgatcc cacatcatct cagtagccag cgcgtgttca cgtccgtctt
     5821 cgaatcgcca ccagccttcc aggagaccaa agacaagatc caaccagaag atgtcacggg
     5881 tcagctcgac aagacacaag attccatcag gtctcaaaag cttgcgaatg ttagtgcaag
     5941 attcccggag gttgcgggtg gcatggacac aattggtcga aagcacgata tcatattgac
     6001 cactcaaagc tgagggaggg tcattttcaa cattcagagt ttcatatcgc atgaaattgt
     6061 agttagcaaa ggtcttccgc ccagctgcaa caagtgatgg tgagatatct gtgaatgtgt
     6121 actccaggcg cgtggacagt ccaggaattg tggacagctt ctcgaggaga ttcttggtag
     6181 tacctcctgt accggcacca atctcaagga tcttgatagt ccggctgctt ccaaatgatt
     6241 gaacaacatc taaaaggtaa cgagcaagat agaggttgcc cgatttgaaa accggagatt
     6301 gcgcgtacac atcgcccacc aagcgccgtg tgttcgcatc ctggaatatc agagatactc
     6361 cgtccgcttt tccagtgaga cagtcagcga gccgaggggc tgtgatttga agaagatcat
     6421 gctccagggc atatggagga tattccgctc ttatctgcgt gtgcaggtca tgcgactgcg
     6481 acaacgggat gggtgttgtt gtgcgcacaa gctccccagt gggcatctgg cggaccaaac
     6541 cgactgactc caagatcttg taaagatgct ttcggagttg ctcgtgacgt ggtagcacag
     6601 agatggggat gagaacttcg tttggttcac tcgcctccag cggagagccc aaagctcgga
     6661 atgcctcgag gatgtaggca gtaagaagtg tcatttgttt cgggtaggtg gtgtggaaga
     6721 agccagtcca gtgagcatcg gaggtgtgag ataccgctgc gtgcgttgtg tcaaagcact
     6781 ggcgggccac tgagactagt ggtggtccat tgttagccgg tgtcggtaca tgggatacag
     6841 cttgtggtgc caccgactgt actggcgctg tttcaacaac aggctgtgag ggggcagcgt
     6901 gagaatgtcc ggggaagata tgttccacca gaccttgaat gttggggatg tccaccaaag
     6961 tggtatacga catatcgact tggaacctct tcttgatttc agaaagaact tcagtgctca
     7021 tgagagagtc caccccaatg tctaccagcg acactgaagg agagacctcc gcgacactga
     7081 ctccaaagag ctcacagagc atctcctgga cagtggcaag atctttagcc ccacctccat
     7141 cggcagccgg cgcactagga gtggctgtca caactgattt ctcagccgga atcgcaggct
     7201 ccacaactga ttgggcttca gcggtctcta ggacattgtt gttcagcttg gccagcgcgc
     7261 gggtgagaga gcggattgag acgctcgtaa atcgaacacc catcattgcc gcagagagtg
     7321 tatctgtttg gcagtccatc acatagatgt cacatgcgat ctcagtctta gacggccgga
     7381 cgtagctggt gtacaccttc catgtcgaag gagaagcgcc attcttttgc ttgagcaagg
     7441 agttgataac aaatgtctcc ccaatagcgt tgcagacaaa gacttcgctt gaccggcgat
     7501 cagaaaggca gttgacgtga attccagcaa cttggaggaa gttgtctagc agaatagggt
     7561 cgcagttggt ctcactggct gatggcatca tggataccag accactggct tcccgaccgt
     7621 ttgcaaatac tttcttcacg ccacggaagt agtctccata gttggttaca gattcaagag
     7681 cagcatagac agtagagccc ttcagcccgt ttgaagcagg gtccgcttca atggttttgc
     7741 ttcgtgccga gtccaacagt cgatccatgg actggaagcg cgccagagcc ctagaacgct
     7801 cctgatgaag acacacggta ccttcagcgt ggaccgatgt atgatcattt gactcactgc
     7861 tgaagatcga aaagagccat ggtcgagtag gacccgctcc atcgctggtg agtctcagga
     7921 acacatctcc ttgtgggtcc aataccaagg gcgaggagat ggtcagatcc tcgatatgtg
     7981 acatggctgg ctcagaagcg ttgcccgtgg ggaaaatgga ggctgctgcc cgcaaaacca
     8041 tctccatgta catggaggcg ggacacaatg tctgattcag aactgcgtgt ccctgggtgc
     8101 atgctctgta gagggcatct tgaatgttaa catgatagag acgctcatct gggctctcgc
     8161 tcaattgaca cagaagacct gcttcttgtc ctgcggactg ctttccagac gaaggtccag
     8221 cagatgaaaa cgctgcaggg tcaaagtcaa cccagtggct gttttgggca aactgatatg
     8281 gtggaaggtt catccatttg aagcttccat gctgggcccg atcgaaaggc cagaactgaa
     8341 catgtacacc ctgtgcccag agggcgctag tgacgtttgc caaattttgg gctccacttg
     8401 aaccacccaa gtcaattttg tggtatgtgt tggcaaccga agagctctct agcactcggc
     8461 gtaccattgg tatgatgggt gaagcggatc ctgcttccag ccagacggcg ggggcttgta
     8521 gcttttcagc tactcgctca acagcacgtc ggaagtacac aggcatgcgg ctgtgctcca
     8581 caatctcagc cgctgtgatg gttgaccagt caccacttgc agagcaggct tcgatgggaa
     8641 tgatcggtgt ctggtaaaca agggacccag ccacctccat gatggcgggc acaatgctat
     8701 cgacaagtcg agaatggaaa gcatgggaat tttgcagccg agtcaaccgc aactttgatg
     8761 cagatggggt tctagcagcg gcgttctcaa tcgccgcgat agattccgct gtacctgcca
     8821 gtacttgctg tcgtggccca ttgtagcagg caacgtcagc gatatgaccc gtctggtcta
     8881 gcagctgttg gacctcaatg tccgtccctt caacggcgag catgatccca gattctgggc
     8941 cccagctgga ctcaatgagg cgagcacgct cagtgactag gtgaatgcca tcgcgaacgc
     9001 tcaagctgcc cgccacagac aaagcagtca actgaccaaa gctgtgtccc acaatgcgac
     9061 tgacacgaag tccagagtcc agccatgcct ttgcagaagc atactgaata gagaagagta
     9121 tgaaatgcaa atggatgatg tttgtgatcg gggctgagct gaagatagtt gggaaaagac
     9181 tgggaaggcc aagcgttcgg cccacttcct cgcaatcttc gaggtgggtc cgtagaagag
     9241 cggaggcgtc gaaaacttcc ttcgaaatgg ttgccgtaag tccattttga ccaccgaaac
     9301 acaaaacaac tgggggctca ttggaaggcc gcttctgaat cagatcggcg gatgcgcccg
     9361 tggaaatggc ctcaagtcgg gcgctcagcg aggtggcgtc cgaagaagtt gaaaaagtga
     9421 gattgagtgg aaggtctcgg ttttgcttca tcgcgaggtt gtatgccaac ttctgcacca
     9481 gagtttcaga tggtgggtgg ctcaaaaggg tcgcgcgaag ggcaccgcag taagcccgga
     9541 gggattcttc agaccgagcg gagaccaaga ttggcacatt ttggatatac tcaggggctg
     9601 ttccgttttg ctcggagcgg atgggagcgt gctccttcac tatgagcgct gcgttgcttc
     9661 ccgatgcccc gtagttgctg accatggcaa cgcgctcggt cgatgcccat tcagtcgact
     9721 ctgaagcgat caccaaccgg tcgggtgtga gagacttgac cttgggattc aactgattga
     9781 agtttgcctg tctcgggatg cgttgttgtt ggagcataag gatggtcttc agcagacccg
     9841 cggccccaga ggatgtctca gtatgcccga tatttccctt gatcgatccg atgtggaggc
     9901 tgtttctgcg ttgagggcca ccaaatgttc tccgaaggct gtccagctca atgggatccc
     9961 cgacttgggt gcctttgtcg ttatcagcaa agctcaaacg gagctatatc gagggaagac
    10021 gtaaagtggg tacataccag tgccatgggc ttccacatag gtgacctcgt caggggaaac
    10081 tccagcgagc gacatagcct tgttatagag tgaccgttgg gcttccgcat cggggactgt
    10141 gattggtgaa ttgttggagc cctggttgac agctgatcca gcgatcacac cgagaattgg
    10201 atctccgttg tcaattgcat cctgcaaggg tcgcagaacg aataacccgg cgccctctcc
    10261 gcggcagtat ccatcggcag aagcgtcaaa gggcttgcat gctccgcttg gtgacaggaa
    10321 agacgcagca ctcaggttct ggtacactct ggggtttgtc aaaacattca caccaccggc
    10381 caaagcgatc ttgcaatcat ttgtttgcag agcctatcac gattagttgc ttttctcgtg
    10441 aaaagaaaaa aacgcggagt atgatactta ctttgcatgc cagatgaata gccactgccg
    10501 ccgatgagca cgctgtgtcc aagctgattg aggggcctga ccagccgaag tgatggctga
    10561 tccgccctgc aatgaacgac tgcagggttc ccgtgatgga gaacgcattc gcgttccttg
    10621 atgccacatt ctctgtataa tcttcagatc cgacaccgac gtaacaccca atatcccgtg
    10681 agagtccgtt tggctgccat cctaagtatc cagcagactc catggcttcg tatgctacct
    10741 gcagcgcgac gcgctgctgg ggatccatgg attcggcttc ccgagccgaa atattgaaaa
    10801 agcgatggtc aaagacgtct gggcgctcca ggaagtgacc ccagaatggg cctttgggct
    10861 cgcgttgcaa gtcggacata tggaatcggc tctcaggggg cgacttcact gtgcaccgac
    10921 ctaactcaag tagatcccac agctgagcga gtgtgtctgc gttgggatac cgacatgcca
    10981 tgccggtgat ggcgatgggc gacgcctcag ccgcctgcgg acgagagtcg aaggtctgca
    11041 cagagtttga caaggacgcc gtggagggct gtgggctttc gttggaaaat ccttgcattg
    11101 cgtagctctg aagttctctt cgtgccaccg acctactcct cgcagaccgt ggaacgaact
    11161 cctcgggtcc aatagacagt aggtgagatt gatcaactgt catttctgtg ctgttgatca
    11221 aagcggagac aacgtcgtac cagtttgctt tggcacaaag aattgagtcc agtgcaacag
    11281 tgtgtagtaa tgcttcttgt tggaatatct ccccgccctg gctcgaccga agcggagtta
    11341 ataaggcatc acttcgagga agcttgaaac gagaatcatt cgtgcataac ttcatgatgt
    11401 gttggattcc ctcgcggtgt gcctcatgat ggaatcgccc tcggagggaa agttgctttg
    11461 tacgaagccc atgatcatgg atctcctgct tcactcgttc tgcgctgtca ttggggatag
    11521 tgatagtgac acttttgacg tctgtgtagc atgatgtgta tcccttgagt atctgttagt
    11581 atttcgttgt tctttcacca ggctttcctt tttgatttat gtgatttttg tataggaaga
    11641 aacttacttc agggttgttg tttaggattt tttcgagatg gttgaagtcc tctacggact
    11701 cccacctgac tgccagtgac gtggttgagc cacacaaaat ctcatccaag tccactagcg
    11761 ctccaacgca aagagaaagg cgtatggcat ttgacgccac atattggaac tcctgtgtgt
    11821 ttcgagagca ggccaccgca attgctgcaa gcagacccac gcagaatcct tgagtatcaa
    11881 ctatccttgg catttctgtc tcagataatg aagatgaagg gaatgctgga tgtgtggcaa
    11941 catcttggag attccagaaa tcaacgatgt gtctcataac agttattggg gtcatcatga
    12001 ggtttgaagc ttctaccctg tcttcactct catgctcaaa aaggcggccg agtgcaagca
    12061 gttgactctc gccttcgaca ttcttcaagg ctggccaggc accggcgatt gttggccata
    12121 aggagggtaa ttcgtcgaga atatttgtga gaaatcccaa acctgtggga tctttggata
    12181 tggcatctcg tatgtgagtg atagaatctg tgatgtccgg gcattgtggt ccaaagagga
    12241 cccgaagatc ttccttcggt tgccctttgt ggaaattcat ggtgtgtagc tcagtgagat
    12301 tgtgaaactt tcaagtaaaa ctttcaaagg atttgtgagt tatatagacc ggtcgtaagc
    12361 cttggctgtg gcaatacggt gaaattgaaa actcccagac agaactccct ggagctcttg
    12421 cgaatcagca atgtgatttg aggcaacaga cagccgggtc cactttaagc atatgagttg
    12481 atttacgcaa cagcttgggg gccaactgag atctcgacct ctcaaggctg tgtatactcc
    12541 gttgagctgt cagtatttaa attaccagaa tttctatagc atggcctgtg tcgatcacct
    12601 tttcgagttt ccaccgattc ggtctcgcca aagacaccca aaacagtatt gactttctag
    12661 ttggaaatga tattattgca tagattgggt tgagacattc tcatggtatc attggacgcc
    12721 ttcaaacata ccgttactaa catctcccag aattgatttt aacatgcctc cgtcaagtac
    12781 gagacttcta gttgcatcat ggtattgata tagtttgcac aatgttttga taaattgtta
    12841 catcggtagt acaatattac aagacatgac ttaattgtct tcccggccct tcttggttac
    12901 ctgtctgcaa ggcgttccac ctgcgcgcgg accgaagaat tatctttagg gaaagcagat
    12961 gaacatattc tgacaagagt ccacatgtaa gccgggcact gtccggacat cgggattttc
    13021 caacatccag atacacgcca tttcatgcag ttaacagctc tgggcatgca gatttgcgcc
    13081 cgaacccctc tttccaagga tggctgttcc atttcccgag gtccttatct ttcccattcg
    13141 agtgtttgcc gtctttcttg ttctggttta atctgatata aatgttgata tctgagtcct
    13201 caacatggtc caggcgtctg actgcatatg ctaaagcaag ctacatccat tagcgtaaat
    13261 ctttaacctt gaaaagagct ttccaaggtg gccaatccat tccattgata tcacatgtgc
    13321 tttagcacgt tcttcaagtt ggatttggtc taattcgtac ataaatacac attcgcggga
    13381 atgcctggtc cattgtcctt tgcaacctgg aaggcaatag cacaatcggc tcaaaggatt
    13441 gcgagaaaaa tggcccccag aacaatcgag agcctgatag agggggctga gttgatgtag
    13501 cagcagcaac atatctccac tagaatcgat taccgtacat attcccattc cagaaagcca
    13561 tgttctagga atgacgcgca tttcccactt tagcctcctc tattggtaat gcaggtgaat
    13621 gtcaccctaa tatgacacaa gtacaatctt ggcagctgga ctccaattcg cttccatggt
    13681 ccagatgtta ggttcgataa ctaagttctg atggcgctgt ttggccctca tgtttatcgt
    13741 caacgaaccc aaaaattggg gtccatgaat ccaagcagaa cttggcttac tgagaggccc
    13801 gaggtcaatg tgaaaagctt ctcacatcat cagccgttcg ggccaaggcc gccacatgct
    13861 tgtttactct tggagtcaac tgtgaaacaa ttacgttgac gctgcttgtc cctgaagcaa
    13921 gctccagggg ctaatttgtc ttgtagtggg gcagatggct aaagatacga aggagacgca
    13981 tgcattagct cgtacatgca cggactaagt ccgctgaaga ggttaaaagc tgtgttaggt
    14041 tacagagcag taagaatcaa aacaaacatt catacggtaa taccgccccc acgcggacgg
    14101 ctccacccga acccaaagct tgattcctgg aagatcgtgt gaccggtaag tgctggttat
    14161 tactgtattt gctaccactg tatttattac aattctttct gcgtccgtac ggattacata
    14221 cttgctaaac aacccacatg tatcgagcaa gcagcatcta cgtgggtaac gcaggtaggc
    14281 ttcaaaagta caatcattac cctgcatcca tggatatgca tcatcttatt tccgaggttg
    14341 tatatattcg gcgctgggat aggcaaatgg tcccaccgct tgattttgca aggcccttac
    14401 ttcaatgttt catggtatca aattccgtct gacaactaga taaaattctc ttcacacaat
    14461 acgtggtaca gtactctatt caaaagatcc gccacagcta tacgagattg acgatgatca
    14521 gtggatccca aagtaagcac tacatgccta ttagtatgta gatgacacac acgccaggga
    14581 cttttcgagt ctgccccact ggcgttagat gaacttacct gcacctcggt ctgcaccacc
    14641 aaagaaagta acctcaactc cgcggggcaa tttcgcatct tcatgttttc attggtctag
    14701 aattgataca acatttgagg aacatcacca gaaggtcatc atcaatcgat tagtcttcca
    14761 tgggtggatt accgatgagc tcaattttga agttactagc cgtgctcaat tgatttggcg
    14821 tttatatcgg ggtttaccga tggcaggtgc caagatggtt gcaccggagt actccttcgt
    14881 agagcacgaa tttgttgagc ttttgtgtta atgtatgacc cgctctgttg cttcaacttg
    14941 cgtaaagtcg gttgatattt cctataccta cggagtagca atgaagtatt tagaattcca
    15001 actcaggaaa ccgcgtaggg cagtggagcc atcttcaatg ggggccagat attccggggc
    15061 cggagtcaaa tacgagccca gatcgggaaa ccgagaaagc atatttcgag tgtatgctga
    15121 aagtttacct gggtattctc ctttaaaggt cattacatgt acaagcttca atacgaacaa
    15181 gttgggtcag aaaaacgccc ccatctcact tggtatgctg cgtgctattc cttttgtggg
    15241 gtggctaggt acttgtctca ctttttgtgg aatcttgata cattctccgc tccgctgtat
    15301 gcaagtttaa cattccttgc actccgtatg aattgggggc ctaagaggat ctgacgtgca
    15361 aatgaggaaa gtgaagtgaa gttgtatctt ttacaaaata tacccatgga catgagagct
    15421 catgggcggt attgatacca ttcctgttac attgcggaaa aacattcaga taacgaaaga
    15481 cgtgctactc ttgtgtttct ctaccaataa gatcttatgt tacaaactag atactaaagt
    15541 ctggctcagt caaatctaag agccgccgtg aaacctccaa cgtccaactg tgtacagctc
    15601 ccaggactat ctgcaatgaa gtctttgtcg ctaacatgga tcacggctgt tgccgtggta
    15661 ctatatctcg tccaacgcta tgtcaggtca tattggcggc tcaaggatat accaggtccg
    15721 gtgttggcaa aactcacaga tctccaacgt gtgtggtggg tgaagactgg ccgagcacat
    15781 gagtttcatc gtgacatgca tgccatgtat ggccctatcg ttcgatttgg accaaacatg
    15841 gtttcagtct ctgatcctcg tgttataccg accatctacc caagtagacc tggattcccg
    15901 aaggtctgtt attgcgattc attgctcccc aaatctccat acgaccggat cccatttgct
    15961 aactctcagg ttccagggtg acttctatcg cacgcaaaag ccatacaccc ggaataaggg
    16021 cgcaatgccc gcggtcttca acactcaaga cgaggatctg cacaagcaac ttcgaagccc
    16081 gatcgcctcg ttatattcca tgacaaatgt ggtgagactc gagccactgg ttgatgaaac
    16141 tcttacagta ctatcgaaac aactcgatga gcgcttcgtg ggtacgaatg ataagccgtt
    16201 cgatctcggg gactggttgc aatatttcgc cttcgactcc atgggcacat tgactttctc
    16261 gcgaagatac ggctttttgg aacaaggtcg tgatatgcat ggaatcttgc aggagatttg
    16321 gaattttatg acccgagtcg ctgtggtggg tacacgcgat taaaataaga tgaaattcaa
    16381 atactaatac aaattcaacg cagatgggac aaattccgtg gtttgacgag atctggaata
    16441 agaattcgtt cattacttta ttcaagcgac ctaccggctt tggtgtgttg aaggttgtcg
    16501 ataactttat atctcaacga gtgtccagtc gtgagaatga cgagaaagca gacgaaaaag
    16561 acatgctttc tcagttcttg gacatccaag catcaaatcc tcactctatc atgccttggt
    16621 aagccacctt ttgatcgaat gatcactttt ctcggaccta attcggctga cgcatttcca
    16681 gggcaccaag agcgtggacc ttctctaatg tcatggctgg ctcagactct actgcgaatg
    16741 tcatgcgtac catgatgtac aaccttctcg ttgaccgaga tacgttgaga agtctgcgag
    16801 ccgagctttt ggaagcggag aactcaaatg gcctgtctcg atccttgcct tcttgggatg
    16861 gagtgagaag cttgccttac cttgatgcat gcgttctcga agctttgcgt ctgcatcccc
    16921 cattctgtct gccctttgaa cgagtcgtcc ctgaaggcgg tatcacagtc tgtgagacat
    16981 atcttccagc gggaacagtt gttggaatta gtccctactt ggccaaccgc gataaacaaa
    17041 cctttggtga tgacgcagat aaatggcgac ccagcagatg gttagatttg agccgcgaag
    17101 atcgggtcaa acttgagaac agtattctca cggtgagtcg aagcttcgat tatgtcaaag
    17161 atgcccttgc tgacgtgtaa acccagtttg gtgcgggacg tcggacttgt ttaggaaaga
    17221 acatcgccat tcttgagatc aagaagctct ttccgatgtt gcttttgaat tatgaagtaa
    17281 gttatcctcc cgtttagata aaatctcttg tgctaatacc acccagatcg aaattgtgaa
    17341 ccctgaaaac taccagacca caaatgcctg gtttttcaga cagtggggct tgcaagcggt
    17401 gattcgcaaa ctgccagcac cagaacgaga tgataccatt gagcagaaag cttccatccc
    17461 gcctgctttg aatattcctc cttcatcttc gacagtcgaa gtgcgaatta ttgactcgta
    17521 agatttcttg attgcctggg ttctacgtta tactgatttg agcacagggg aacactactt
    17581 gatctgagac ctgatctatt ctggacacct gatctcccag ggcttctgaa ggtcacagct
    17641 ccaacttact gctttttgat ctcaaatggc actcgacacg ttctgtttga cctagctgtc
    17701 cgacaagact gggaaaacct cccaccatcc attgtggcca tgatcaaatc gcaaacggtc
    17761 atccaagagc cacgcaacat ctcagatgtt cttgactcag acgaatcctc tctgggggtc
    17821 cggagcaaag atattgaagc gattatctgg tcacatgccc attttgacca cattggtgac
    17881 ccatcaactt tccccccgtc taccgagcta gtcgtcggac ctggcatccg agacacccac
    17941 tggcccggct tcccaactaa cccagacgca atcaacctca acaccgacat ccaaggtcgc
    18001 aatgtgcgag aaatttcctt cgaaaagaca cagaagggag ccaccaagat cggttctttc
    18061 gacgccgtgg actattttgg cgatgggtcc ttttatcttc tagatgctgc gggtcattcc
    18121 gtgggccata tcggtgctct tgctcgcgtg actacctctc cagtctcgtt tgtcttcatg
    18181 ggtggtgact catgtcacca tgccggagtg cttcgaccca caaaatatct tccttgtcca
    18241 cttgactctg gtgacacttc acttccatgc aaatccgact ctgttttcac gttatcgcct
    18301 gcactgccaa ctgattacac tgctgctttg aggacagtcg agaatattaa ggagctcgat
    18361 gcctgtgagg atgtattcgt cgtccttgct catgatgcta ccttgaaagg gaaggtcgac
    18421 ttttaccctt cgaaaatcaa tgattggaag gcgaaagagt acggcaagaa gacaaagtgg
    18481 cttttttaca aggatattga gaattccata gaaggacaga agtaaatagt gcatgtttaa
    18541 aagtcaattt tcaccaatca agccttgaga tatttggaat tgttcaaaca aaccataggc
    18601 tttcaaaaat gatgagaata ttgagaagta accagttaca aattttggtt ggcgtaatgt
    18661 actagtttga aagttttgcg gtaagttcat ctcgtaaaat gaacttttct tccgactgat
    18721 acgattggtg tggccatggc ttgatcgaat tcgcatttac atctatggac atgattctac
    18781 gattttatcc aagacataca tcactaggaa agtcttcgaa acaatatggg gcctactggt
    18841 tttttggcag gcgcttcaaa atgtgtattt cttagtgtaa actaactttt ggtttgccca
    18901 gataactggg atagacgtaa tttttcacaa tgtgcgacac gcacagaggc tttcctttta
    18961 agaagagtac aacttcttct cgtggctgtg aagaccgtga acattgccct cggtctgcgc
    19021 gctggcgctt ctcatctcaa agcgaacctg tccgttgttc acaccggtgt gcagggcctc
    19081 aagatcctga acaccgatat cctggagaga gtgctgaata ccagcaacaa ggtaaggcac
    19141 gtattgcgtg atggaaccgc ggtcgacgac agagcccgca acaccctggg cgaccttgac
    19201 cttgtcgttc tcagagaagt agcgggaagc gccagcgttc ttgccgccac cactcttgcc
    19261 cttgtcctcc ataacagcga tactacccat accgcggaag gccttgacca gctgaccttc
    19321 attgctaacg tagtactcgc caggagactc ggtagtaccg gcaagcaagc ttcccatcat
    19381 aactgcggag gcaccaagtg caaggccctt gacaatgtgt cccaggttct ggacaccgcc
    19441 gtcggcgata gtaggaacgc cgaaacgggc ggcgaaggca gaaacactgc ggacggaagc
    19501 agcctggggg cgaccgacgg ccatgacttc ttgggtaatg catgcggagc cactgcccat
    19561 accgatacgc agaccgtcgg caccagcggc aatcagtgcg gcggcctgct cacgggtaac
    19621 gatgttaccg gcgatgatat cgatgtctgg gaaggtagac ttgatccact taatcatagc
    19681 aatctggtac atgctgtttc cctggctgct gtccacaacg acaatgtcga gaccagcgtc
    19741 gacgagcttc tgaaggcgga ccttgtcagc gtcgtgggtg ctgatagccg cagcgcagag
    19801 cagctgcttg gatggaagct tggatgcgag gggatagtgg atattcttca tcagatcact
    19861 gcgagagagg agggagacca ataatccgtc cttgtccaca atgggaagct tgcccttctt
    19921 ggagctgcgg aggacttcat tggcttcagc cagggtggtt cccgcgggtg cggtgacaag
    19981 gtcagtcgac ataacggctg tgactggatc ctctggagtc ttgtggaact ggatatctct
    20041 gctagtgacg atgccgagaa gcttggagtg gagagtgccc ttctctagaa gcgaaaacga
    20101 gtcagaactt gccaacttcc cgaaggagga taagtaatgt gtcttaccgg tcactgggaa
    20161 tccgccgaag ttccatttgg tcttcaattc ctttgcctct gcgacggttg tgctagggga
    20221 cagaacgacg gggtcgagga tgaagccgtt ctcatagcgc ttcaccttcc tgaccatctc
    20281 agcttggtca tcgggtgggc agttgttgtg aataactccc agaccgccca gaagagccat
    20341 gtgaatagcc atgttatgtt cggtcaccgt gtccatgggg gacgagagga gtggggcctt
    20401 gatggtgaac cgccgggtca ccttggtatc caaagaaacg tccgctgctg agaaagcttt
    20461 ggacgagatt agaatacatg gcgggcacga atgaggatca gtatcttact gatagagccg
    20521 ggcaggatga ggaagtcatt gtaggtcaag gctccgtggt tgtcggagtc gagaagggta
    20581 tcgacatgga gaccatctcc ggaaggatac tccttcagga cctccaaggc cttggtgtag
    20641 tccaggattt cgaccattat ttatgtggag agataagatt ggagagaaac agtatgaaat
    20701 ttttgagggg gaatagttcc caaagaaatt cagaggggca ggggggaggg gtgcctattt
    20761 aacagggggc ccaaaagtgg catgcttagc gaaacgcctc tcatgtacga tctttgctcg
    20821 aaggccgttt gaacccgtgg gtttaattga ctaatgagct tgttatacgc ttgtaatata
    20881 acgctagcag gggtggtaag gagaagcgac caatcaatgc gaaactagtc atatttatag
    20941 atcgtcggtg tggaacgaag gatgacgctt gatctgcctg agccatgcct aaacggggaa
    21001 gaatacaggg atcctgaccc acagccccac actaccccag tccctagaaa gggcattggt
    21061 tgaaattttg gaaatgtaac tgactcaata cgcccggggt gtctccgagg cccggacacc
    21121 agccttcggc cccgctttac cgaagtttga gcgccgctaa gaaccttgga tgatcgcagc
    21181 ctagactttc taaggttggg ggctaaatct ggctttgttt gactctgacg gaaacaaatt
    21241 tctaattctt cttttaacgt ttagaacccg acgttcaggc gagttccgct tcaatcaaac
    21301 tctctgccac gccgggatac gagtatatgt tgactacctt caacccggcc cgggtcagaa
    21361 tggatctcca atcggcctct gttctctcct tggcccccat gtgggccagc atgatcaagt
    21421 ccatgttggt cgctgacatc actgggctct cctcgtcaac aacaatctca ttgaggagca
    21481 cacgggagta acccttcgcc aaagcaggaa caaggttggc catgatctta actgcatcct
    21541 cgtctccgaa gccgtgagga acggagtgca tgtagtaagc ccgagcattc ttcacgggct
    21601 gcgttgtgaa gatgtcatgg gtcgtcgctt caaattgacg ggactcatca gcggggatgc
    21661 tgttgatgac ctgttctcga tcttgaagaa caagtcttcc tgggagcgga ctgaattgag
    21721 agccgaaggt ggcgatgtca tgaccacgac caccgccgac gtcgaccagc agaacatcgc
    21781 tcacagaggc gtcaaaccca ttcagaagac ggtctgcgac agggtaaaag ccgttgtcac
    21841 accagttcgg ctttccagcg cggtaggcac tcatgtaaga gttgaagtat tgcaggtaag
    21901 ggggatttcc gacaagccat tgtgggaatg aaatgtcaac cttgtgtgca gattggaatg
    21961 ggccatcagt ggtgcccagg gcaggggtct tgtacccatt gcctttgaaa aagctcggga
    22021 aggcaccgaa cgagggcctg gacacatcat gacagaagcg gattgattgt tgatagtttt
    22081 cagcggcaag gccgttgctc aaggctgtgc catagaacac tccgttgcgg gaagtgatca
    22141 cgttcatggc cacaagatgt ctggccaagc gtgcgaaaag gctcacatcc atgccagtct
    22201 ttgaggccag agcttcggcg ctcaaaccct cttcttgggc atctttcagg tattggaaaa
    22261 ggtttacatc ggtagcaagt ctgacgatag cagaaagggc gggctatttg ctcattagct
    22321 atgcttccaa ggtttcaatg accagccaag ctcacctgag accagaaggt gtgttggatg
    22381 aactcgcttg gaacttcaag tgaggcaatc aaggctctgc tctgagcaat gagagcttcc
    22441 cttgcaccag attcattgtt ctcgtattgt ttggctgccg acgcaagctc ctggataatg
    22501 gaggctgggg atgcggcact catgatgttt ctcgtggaag gctgcggaaa agagtatcac
    22561 cggagagaga taggtacggt gtcatggcta gaggctattg tatttgtagc cattttcgga
    22621 gggggatcga gatctctgtc tttcaaggtt tcgcccttcc tacacggcaa tttggcccct
    22681 cgacctacag tgacccaaca agttgatgat ttgggggcta ttcatgcatg tctccagttt
    22741 cgtaagactt aattggcatt tacaagtaca gtgtgctcca ggcctacaat ttctggaatg
    22801 gacagacgaa gcggggtcga agttgttcgc aatttcgcga tatcatatct ttgctctagg
    22861 gcttatgtgt atggagctta tattttcgcc ctgtgggcca tctacagcat gtatacgtac
    22921 tctgtattgt aggctgtcac gatccacttc tgcatctggc cctcggataa attacattgt
    22981 aagaagtacg gagtatggag tggtatctga cgatttgggg tctcgccacc cgattcagca
    23041 tcatatccag agcccaccgg cctacaggtt gaaggatgct actctgcata gtacgtagat
    23101 ggagtgttgc agcctaatgc aaggttttcc tcactccact ttgggggcga gaatgatcgg
    23161 ggtacggtat ggtatatgcg ccgacatctt gaaagtcggt tttaatctca tattacgtcc
    23221 tgttatgact cgtttcgcat gtttcgcaaa aatacgcaac gaaaaaggag caagacccga
    23281 gcaatgtttc gggaaagtgg atcctctgaa aatacgcgca cgcccttgta ttcgtatttt
    23341 gagctagcgg gaggatacat ggaaggcggg tcttcccgct tactgtagat ccgctagtaa
    23401 caataccagc cttggaacat caacagcctt gaaatctcat ctcgtaagaa ttatcaatgg
    23461 caactaccaa cttcaatgta agacctcgtg tcatcgtggg ccttgttaca ttgacttcgc
    23521 cacttccaaa ttgaagttga actatactcc aatgcgtaac cgaccacatc ggtcaagggg
    23581 gcgggattca ggcccaccac tccgcatgca tagctggatt gacactggga gagaattttc
    23641 tttgcagtcc tgtacaagtt tacgtggcta gatttctggc cccaatatcc aagagtagaa
    23701 gcccggtcac catgatgtga tttctttttt caggttgcct tgtagcgcaa acgaaggaaa
    23761 ttgcactgcc ctcgaacgtc atctttcttt gcacattcta caattacaga gtctaggtga
    23821 gcctggcctg aaaatcataa ggtactcccg aggtcaacct tggaatgtgc cttatactta
    23881 actcgaagag ataaggatga tatgtacaag aaatcgagac atattggaga atatacatag
    23941 ttttacatct gagaatccgc gacaaataac tcctttctgc ttgtaacctg caatctgcca
    24001 gctatctaaa gttttccctt atcactcctc ttcttgcgtc cagtaggaat tggcttcaaa
    24061 accttatacc aattttcttc aaccgcctga tgacttttcc catccctgtc ttctttccac
    24121 tgtctttcag tctgacggaa tcgatccatc tcctgctgaa gccagaccac acatgttcct
    24181 gcaacggtct tcacttcttg gaatggcatc aaatgcccaa accctggaag aacaacctcg
    24241 cgaaccctcc catccggcac acctccgctc ccaccaatac ctgatccgca tatcttgaca
    24301 ccttcgcgta tctcatcgat gttcaaaaac gtagcgccgg ctatgaccca taagcatgac
    24361 ggtcgaagcg tctccagacg acggaatgtg cttcggggtt ccgggcggta caatggaata
    24421 taagcaacca gtggatccat gtcggcatga gtgtcgcgcg gaacttcaat gcgacctgtc
    24481 ttcgggtcac gggcattgaa gttttgtcga atttgagcta cgagctcatg atattttggt
    24541 gtcgtcaaag tgactggagt ggtagtagag tccgcagtgg ttccaaagcg agcctttatg
    24601 gcctcaacat ctgggtagag tggggttggt agatcgcgaa agaagtgttt cgtcatgcga
    24661 tccaagcatc ggggatccat gccttgcatg atagcgcggt tggcgcgtat tgcttcttcc
    24721 cggcttggcc atacatcatc tcgccagaga gtgtagttga tcgcacttgg agcatcggtt
    24781 ccaaagccca aagagggtgg acttagctga ataagaggat ctagcagtag gagagtagta
    24841 aaaagacggg gatgcaagta ggcaaggttg gtgctaaaag aaaaagccag tcagtgcctt
    24901 atcatctcat tgcttgagat gggcaggtga gattcatcac aaacataata ttgccaccaa
    24961 agctgtggcc gattccaact agaggacgtg gcatctggtc ccggaaatgg ttgatcatca
    25021 acaaaaggtc tcgggcatga tccatccagg agcctaggat tgattcttta gtccagtgag
    25081 aagtattagc agccagatgc acatacaatc catgctgagc ttgtcttcat tgtgaatgcc
    25141 actctgattc atgctggcga catcggccat ccatatggca cggatatgaa atccagaagc
    25201 ttggtctagg agctcatccc atagtggctc atacagctcc tgtatttaat agatgagtat
    25261 acgaggaaca acacaaggtc ataagagcac tcacctttgg cagaccgact ccgtgagtgg
    25321 caatgaaagt gattgcatcg tctggaaccg gaccctctcg tttaggagta taatttttga
    25381 catgaatctt caaaacatcc tgctggttaa ccgtacttcc gggatattcc ctaatatggc
    25441 tgcctgggac caggtgctca gtgatggtaa atttctcagt tgacat
//
