BGC0000104: mycophenolic acid biosynthetic gene cluster from Penicillium brevicompactum
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Location: 7,000 - 32,485 nt. (total: 25,486 nt).
This entry is originally from NCBI GenBank HQ731031.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000104
Short description mycophenolic acid biosynthetic gene cluster from Penicillium brevicompactum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type I)
Loci
HQ731031.1
7000 - 32485
via Knock-out studies
Compounds
  • mycophenolic acid
Species Penicillium brevicompactum [taxonomy]
References
Chemical products information
mycophenolic acid Evidence: Mass spectrometry [1]
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C17H20O6
Chemical database entries
ChEBI
NPAtlas
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADY00128.1
  • mpaA
 7000 - 8136 (-) putative prenyl transferase
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    • ADY00129.1
    • mpaB
    		 9643 - 11119 (+) MpaB
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      • ADY00130.1
      • mpaC
      		 11535 - 19279 (-) polyketide synthase
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        • ADY00131.1
        • mpaD
        		 22778 - 24179 (+) putative P450 monooxygenase
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          • ADY00132.1
          • mpaE
          		 24739 - 25524 (+) putative metallo-beta-lactamase superfamily II enzyme
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            • ADY00133.1
            • mpaF
            		 25957 - 27656 (-) putative inosine monophosphate dehydrogenase
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              • ADY00134.1
              • mpaG
              		 28274 - 29522 (-) putative O-methyltransferase
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                • ADY00135.1
                • mpaH
                		 31005 - 32485 (-) putative hydrolase
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                  Biosynthesis information
                  Annotation changelog

                  Entry version: next

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2024-06-11
                  MIBiG v4 annotathon
                  • (ID: W3QOK3QPXTRJDCB4DPJ3LOBQ)
                  • (ID: XBXL5Y5CH4BE3EYSVTFNOISJ)
                  • (ID: MHEG72J5P6EVQJZ6TDG3KBTM)
                  • (ID: RKFOW2BJ2UIGZ6GYHFZX4BHF)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 3

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-10-07
                  Update chemical activity to schema version 2.11
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 2

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2019-10-16
                  Migrated from v1.4
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2019-10-16
                  Updated compound(s) information (NPAtlas curation)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2015-06-12
                  Submitted
                  • (ID: 4CPIGDAOCCI5BMKFFN3C7RIM)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  Detailed domain annotation
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