BGC0000104: mycophenolic acid biosynthetic gene cluster from Penicillium brevicompactum
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Location: 7,000 - 32,485 nt. (total: 25,486 nt).
This entry is originally from NCBI GenBank HQ731031.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
Polyketide
Terpene
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000104
Short description mycophenolic acid biosynthetic gene cluster from Penicillium brevicompactum
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Other)
  • Terpene (Sesquiterpene/Dolichol)
Loci NCBI GenBank: HQ731031.1
Compounds
  • mycophenolic acid
Species Penicillium brevicompactum [taxonomy]
References
Chemical products information
mycophenolic acid
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C17H20O6
Chemical database entries
NPAtlas
PubCHEM
ChEBI
ChEMBL
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADY00128.1
  • mpaA
 7000 - 8136 (-) putative prenyl transferase
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  • ADY00129.1
  • mpaB
 9643 - 11119 (+) MpaB
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  • ADY00130.1
  • mpaC
 11535 - 19279 (-) polyketide synthase
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  • ADY00131.1
  • mpaD
 22778 - 24179 (+) putative P450 monooxygenase
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  • ADY00132.1
  • mpaE
 24739 - 25524 (+) putative metallo-beta-lactamase superfamily II enzyme
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  • ADY00133.1
  • mpaF
 25957 - 27656 (-) putative inosine monophosphate dehydrogenase
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  • ADY00134.1
  • mpaG
 28274 - 29522 (-) putative O-methyltransferase
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  • ADY00135.1
  • mpaH
 31005 - 32485 (-) putative hydrolase
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Polyketide-specific information
Subclass Other
Starter unit Acetyl-CoA
Cyclic? yes
Release type
  • Hydrolysis
Polyketide-synthases
Genes Properties Modules
mpaC Synthase subclass: Iterative type I
Iterative PKS type: Non-reducing, C2-C7 first
Iteration counts: 3
Terpene-specific information
Carbon count subclass Sesquiterpene
Structural subclass Dolichol
Prenyltransferases mpaA
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 4CPIGDAOCCI5BMKFFN3C7RIM, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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