BGC0000111: neocarzilin A biosynthetic gene cluster from Streptomyces carzinostaticus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 33,079 nt. (total: 33,079 nt).
This entry is originally from NCBI GenBank AB097904.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000111
Short description neocarzilin A biosynthetic gene cluster from Streptomyces carzinostaticus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB097904.1
via
Compounds
  • neocarzilin A
  • neocarzilin B
Species Streptomyces carzinostaticus [taxonomy]
References
Chemical products information
neocarzilin A Evidence:
Copy SMILES
C14H17Cl3O2
Chemical database entries
NPAtlas
neocarzilin B Evidence:
Copy SMILES
C13H15Cl3O2
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAD38870.1
 310 - 1563 (+) putative ion antiporter
    copy AA seq
    copy Nt seq
    • BAD38871.1
    		 1645 - 4449 (+) putative activator
      copy AA seq
      copy Nt seq
      • BAD38872.1
      		 4513 - 6156 (+) putative halogenase
        copy AA seq
        copy Nt seq
        • BAD38873.1
        		 6338 - 12655 (+) polyketide synthase
          copy AA seq
          copy Nt seq
          • BAD38874.1
          		 12652 - 21918 (+) polyketide synthase
            copy AA seq
            copy Nt seq
            • BAD38875.1
            		 21915 - 24353 (+) polyketide synthase
              copy AA seq
              copy Nt seq
              • BAD38876.1
              		 24350 - 25156 (+) thioesterase
                copy AA seq
                copy Nt seq
                • BAD38877.1
                		 25156 - 25677 (+) putative flavin reductase
                  copy AA seq
                  copy Nt seq
                  • BAD38878.1
                  		 25808 - 26941 (+) putative acyl CoA synthetase
                    copy AA seq
                    copy Nt seq
                    • BAD38879.1
                    		 26943 - 28100 (+) putative dehydrogenase alpha subunit
                      copy AA seq
                      copy Nt seq
                      • BAD38880.1
                      		 28097 - 29083 (+) putative dehydrogenase beta subunit
                        copy AA seq
                        copy Nt seq
                        • BAD38881.1
                        		 29094 - 30422 (+) putative acyl transferase
                          copy AA seq
                          copy Nt seq
                          • BAD38882.1
                          		 30583 - 32454 (+) putative oxidoreductase
                            copy AA seq
                            copy Nt seq
                            • BAD38883.1
                            		 32447 - >33079 (+) putative oxidoreductase
                              copy AA seq
                              copy Nt seq
                              Biosynthesis information
                              Annotation changelog

                              Entry version: 4

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-10-07
                              Update chemical activity to schema version 2.11
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 3

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-09-15
                              Updated bioactivity data
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 2

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2019-10-16
                              Migrated from v1.4
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              2019-10-16
                              Updated compound(s) information (NPAtlas curation)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2015-06-12
                              Submitted
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              Detailed domain annotation
                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                              A domain glossary is available here, and an explanation of the visualisation is available here.
                              Selected features only
                              Show module domains
                              Similar known gene clusters from MIBiG 4.0
                              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                              Click on reference genes to show details of similarities to genes within the current region.
                              Click on an accession to open that entry in the MiBIG database.