BGC0000114: nigericin biosynthetic gene cluster from Streptomyces violaceusniger
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Location: 1 - 95,700 nt. (total: 95,700 nt).
This entry is originally from NCBI GenBank DQ354110.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000114
Short description nigericin biosynthetic gene cluster from Streptomyces violaceusniger
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type I)
Loci
DQ354110.1
via Gene expression correlated with compound production
Compounds
  • nigericin
Species Streptomyces violaceusniger [taxonomy]
References
Chemical products information
nigericin Evidence: NMR, Mass spectrometry
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C40H68O11
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABC84455.1
 420 - 1232 (-) NigE
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    • ABC84456.1
    		 1475 - 8722 (+) NigAI
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      • ABC84457.1
      		 8764 - 15465 (+) NigAII
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        • ABC84458.1
        		 15507 - 27758 (+) NigAIII
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          • ABC84459.1
          		 27775 - 39942 (+) NigAIV
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            • ABC84460.1
            		 39985 - 52122 (+) NigAV
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              • ABC84461.1
              		 52139 - 57244 (+) NigAVI
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                • ABC84462.1
                		 57331 - 58197 (-) NigCII
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                  • ABC84463.1
                  		 58370 - 59629 (+) NigD
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                    • ABC84464.1
                    		 59705 - 60043 (-) NigAXI
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                      • ABC84465.1
                      		 60152 - 64051 (-) NigAX
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                        • ABC84466.1
                        		 64048 - 65478 (-) NigCI
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                          • ABC84467.1
                          		 65513 - 65980 (-) NigBIII
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                            • ABC84468.1
                            		 66016 - 66453 (-) NigBI
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                              • ABC84469.1
                              		 66450 - 72278 (-) NigAIX
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                                • ABC84470.1
                                		 72327 - 78947 (-) NIGAVIII
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                                  • ABC84471.1
                                  		 78995 - 93358 (-) NigAVII
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                                    • ABC84472.1
                                    		 93400 - 93948 (-) unknown
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                                      Biosynthesis information
                                      Annotation changelog

                                      Entry version: 4

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-10-07
                                      Update chemical activity to schema version 2.11
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 3

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-09-15
                                      Cleaned up synonym list
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                                      2022-09-15
                                      Corrected gene identifiers
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                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2022-09-15
                                      Updated bioactivity data
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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                                      Entry version: 2

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2019-10-16
                                      Migrated from v1.4
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2019-10-16
                                      Updated compound(s) information (NPAtlas curation)
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                                      Entry version: 1

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2015-06-12
                                      Submitted
                                      • (ID: CKAYQ42GR5EX6WJLHMEET7FX)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      Detailed domain annotation
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