BGC0000117: oligomycin biosynthetic gene cluster from Streptomyces avermitilis
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Location: 1 - 104,326 nt. (total: 104,326 nt).
This entry is originally from NCBI GenBank AB070940.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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Gene details
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General information about the BGC
MIBiG accession BGC0000117
Short description oligomycin biosynthetic gene cluster from Streptomyces avermitilis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB070940.1
Compounds
  • oligomycin
Species Streptomyces avermitilis [taxonomy]
References
Chemical products information
oligomycin
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C45H74O11
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAB69185.1
  • mcmA
 1 - 1134 (-)
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  • BAB69186.1
  • pptA
 1131 - 1886 (-) phosphopantheteinyl transferase
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  • BAB69187.1
  • simX4_homolog
 1910 - 2875 (-) SimX4 homolog
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  • BAB69188.1
  • olmC
 3213 - 3971 (+) thioesterase
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  • BAB69189.1
  • olmRI
 4643 - 7438 (+) luxR-family transcriptional regulatory protein
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  • BAB69190.1
  • olmRII
 7658 - 10486 (+) luxR-family transcriptional regulatory protein
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  • BAB69191.1
 10933 - 11271 (+) P450-like protein
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  • BAB69192.1
  • olmA1
 11458 - 29898 (+) modular polyketide synthase
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  • BAB69193.1
  • olmA2
 29924 - 44446 (+)
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  • BAB69194.1
  • olmA3
 44452 - 56271 (+) modular polyketide synthase
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  • BAB69195.1
  • olmA6
 56417 - 70474 (+) modular polyketide synthase
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  • BAB69196.1
  • olmA7
 70533 - 81374 (+) modular polyketide synthase
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  • BAB69197.1
  • olmB
 81845 - 83059 (-) cytochrome P450
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  • BAB69198.1
  • olmA5
 83255 - 88978 (-) modular polyketide synthase
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  • BAB69199.1
  • olmA4
 89127 - 101039 (-) modular polyketide synthase
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  • BAB69200.1
 101284 - 101787 (+) hypothetical protein
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  • BAB69201.1
  • ccrA
 101928 - 103280 (+) crotonyl-CoA reductase
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  • BAB69202.1
  • hbdA
 103501 - 104319 (+) 3-hydroxyacyl-CoA dehydrogenase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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