BGC0000117: oligomycin biosynthetic gene cluster from Streptomyces avermitilis
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Location: 1 - 104,326 nt. (total: 104,326 nt).
This entry is originally from NCBI GenBank AB070940.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
Compounds
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Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000117
Short description oligomycin biosynthetic gene cluster from Streptomyces avermitilis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB070940.1
via
Compounds
  • oligomycin
Species Streptomyces avermitilis [taxonomy]
References
Chemical products information
oligomycin Evidence:
Copy SMILES
C45H74O11
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAB69185.1
  • mcmA
 1 - 1134 (-)
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    • BAB69186.1
    • pptA
    		 1131 - 1886 (-) phosphopantheteinyl transferase
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      • BAB69187.1
      • simX4_homolog
      		 1910 - 2875 (-) SimX4 homolog
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        • BAB69188.1
        • olmC
        		 3213 - 3971 (+) thioesterase
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          • BAB69189.1
          • olmRI
          		 4643 - 7438 (+) luxR-family transcriptional regulatory protein
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            • BAB69190.1
            • olmRII
            		 7658 - 10486 (+) luxR-family transcriptional regulatory protein
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              • BAB69191.1
              		 10933 - 11271 (+) P450-like protein
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                • BAB69192.1
                • olmA1
                		 11458 - 29898 (+) modular polyketide synthase
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                  • BAB69193.1
                  • olmA2
                  		 29924 - 44446 (+)
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                    • BAB69194.1
                    • olmA3
                    		 44452 - 56271 (+) modular polyketide synthase
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                      • BAB69195.1
                      • olmA6
                      		 56417 - 70474 (+) modular polyketide synthase
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                        • BAB69196.1
                        • olmA7
                        		 70533 - 81374 (+) modular polyketide synthase
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                          • BAB69197.1
                          • olmB
                          		 81845 - 83059 (-) cytochrome P450
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                            • BAB69198.1
                            • olmA5
                            		 83255 - 88978 (-) modular polyketide synthase
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                              • BAB69199.1
                              • olmA4
                              		 89127 - 101039 (-) modular polyketide synthase
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                                • BAB69200.1
                                		 101284 - 101787 (+) hypothetical protein
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                                  • BAB69201.1
                                  • ccrA
                                  		 101928 - 103280 (+) crotonyl-CoA reductase
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                                    • BAB69202.1
                                    • hbdA
                                    		 103501 - 104319 (+) 3-hydroxyacyl-CoA dehydrogenase
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                                      Biosynthesis information
                                      Annotation changelog

                                      Entry version: 4

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-10-07
                                      Update chemical activity to schema version 2.11
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 3

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-09-15
                                      Updated bioactivity data
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 2

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2019-10-16
                                      Migrated from v1.4
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 1

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2015-06-12
                                      Submitted
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      Detailed domain annotation
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