BGC0000118: pactamycin biosynthetic gene cluster from Streptomyces pactum
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Location: 1 - 42,898 nt. (total: 42,898 nt).
This entry is originally from NCBI GenBank AB303063.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000118
Short description pactamycin biosynthetic gene cluster from Streptomyces pactum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB303063.1
via
Compounds
  • pactamycin
Species Streptomyces pactum [taxonomy]
References
Chemical products information
pactamycin Evidence:
Copy SMILES
C28H38N4O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAF92582.1
 <3 - 1882 (+) ATP-dependent RNA helicase
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    • BAF92583.1
    • pctA
    		 3807 - 5000 (-) cytochrome P450 monooxygenase
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      • BAF92584.1
      • pctB
      		 5054 - 5542 (-) glutathione peroxidase
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        • BAF92585.1
        • pctC
        		 5759 - 6934 (-) aminotransferase
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          • BAF92586.1
          • pctD
          		 6949 - 8661 (-) carbamoyltransferase
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            • BAF92587.1
            • pctE
            		 8934 - 10037 (+) Fe-S Radical SAM oxidoreductase
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              • BAF92588.1
              • pctF
              		 10103 - 11179 (+) methyltransferase
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                • BAF92589.1
                • pctG
                		 11172 - 11708 (-) hypothetical protein
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                  • BAF92590.1
                  • pctH
                  		 11708 - 12358 (-) hypothetical protein
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                    • BAF92591.1
                    • pctI
                    		 12534 - 13670 (-) putative deacetylase
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                      • BAF92592.1
                      • pctJ
                      		 14089 - 16074 (+) methyltransferase
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                        • BAF92593.1
                        • pctK
                        		 16106 - 16390 (+) acyl carrier protein
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                          • BAF92594.1
                          • pctL
                          		 16396 - 17352 (+) glycosyltransferase
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                            • BAF92595.1
                            • pctM
                            		 17349 - 19037 (+) ketoacyl-ACP synthase
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                              • BAF92596.1
                              • pctN
                              		 19030 - 20757 (+) methyltransferase
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                                • BAF92597.1
                                • pctO
                                		 20808 - 22544 (+) methyltransferase
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                                  • BAF92598.1
                                  • pctP
                                  		 22548 - 23603 (+) putative NAD dependent dehydrogenase
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                                    • BAF92599.1
                                    • pctQ
                                    		 23914 - 24687 (-) hydrolase
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                                      • BAF92600.1
                                      • pctR
                                      		 24797 - 25432 (+) phosphopantetheinyl transferase
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                                        • BAF92601.1
                                        • pctS
                                        		 26388 - 31973 (-) iterative type I PKS
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                                          • BAF92602.1
                                          • pctT
                                          		 31970 - 33046 (-) ketoacyl-ACP synthase
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                                            • BAF92603.1
                                            • pctU
                                            		 33060 - 34577 (-) putative AMP-forming acyl-CoA synthetase
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                                              • BAF92604.1
                                              • pctV
                                              		 34574 - 35908 (-) aminotransferase
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                                                • BAF92605.1
                                                • pctW
                                                		 36069 - 36908 (+) putative short-chain dehydrogenase/reductase
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                                                  • BAF92606.1
                                                  • pctX
                                                  		 36946 - 37626 (+) putative phosphatase
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                                                    • BAF92607.1
                                                    		 38551 - 39366 (+) hypothetical protein
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                                                      • BAF92608.1
                                                      		 40102 - 41397 (+) integral membrane protein
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                                                        • BAF92609.1
                                                        		 41963 - >42898 (+) probable peptidase
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                                                          Biosynthesis information

                                                          No biosynthesis information available for this record.

                                                          Annotation changelog

                                                          Entry version: 4

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-10-07
                                                          Update chemical activity to schema version 2.11
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 3

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-09-15
                                                          Updated bioactivity data
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 2

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2019-10-16
                                                          Migrated from v1.4
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 1

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2015-06-12
                                                          Submitted
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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