LOCUS       BGC0000120             40217 bp    DNA     linear   PLN 01-DEC-2016
DEFINITION  Penicillium expansum strain NRRL 35695 patulin biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0000120
VERSION     BGC0000120
KEYWORDS    .
SOURCE      Penicillium expansum
  ORGANISM  Penicillium expansum
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Penicillium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 16:29:17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 40217
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..40217
                     /country="France"
                     /db_xref="taxon:27334"
                     /isolation_source="grapevine berries"
                     /mol_type="genomic DNA"
                     /organism="Penicillium expansum"
                     /strain="NRRL 35695"
     misc_feature    1..40217
                     /note="patulin biosynthetic gene cluster"
     subregion       1..40217
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000120"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..40217
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(join(<195..652,743..1315,1367..1746,1819..1882,
                     1936..>2035))
                     /gene="patH"
                     /product="M-cresol hydroxylase"
     gene            complement(<195..>2035)
                     /gene="patH"
     CDS             complement(join(195..652,743..1315,1367..1746,1819..1882,
                     1936..2035))
                     /codon_start=1
                     /gene="patH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 192.6; E-value: 2.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /note="CYP619C3 cytochrome P450"
                     /product="M-cresol hydroxylase"
                     /protein_id="AIG62144.1"
                     /transl_table=1
                     /translation="MEPFLLLLLVLLPAIVLVRYAFTYGHRTSTMPIGPPTLPFIGNIH
                     QITKKYTHIKFTEWAAQYGGLYMLKIGNGNMAVITDRRLVKEVLDRKSGIYSHRPHSFV
                     SHDLITKGNHLLVMHYGDQWRTFRRLVHQHLMETMVENHHTKIVNAEAIQLVRDYMIDP
                     EHHMAHPKRYSNSITNSIVFGIRTANREGANMRRLYKLMEEWSEVMETGATPPVDLFPW
                     LKLLPQWLFNNYIDRAKAIGVQMETLYVDILNKVIKRREDGHNNGTFMDKVLDSQEKHN
                     LPWHQLAFIGGVLMEGGSDTSSSLTLAIVQALIQNPDVQRKAHAEIDAVVGHNRSPVWE
                     DFEKLPYINMIIKEGHRWRPILPLCFPHALGEDDWVDGKFLPKGTIVVVNTWGMHMDPS
                     QPDDPAAFIPERFAKHPQLAPDYVPGTWERRDHYGYGVGRRICPGIHLAERNMFLGIAK
                     LLWAFDFQPGEGPIDSDPVTGYHNGFLYCAKDYSCRPVIRNEVIRDTIEREYATATADV
                     FSRFTEG"
     mRNA            complement(join(<2810..3732,3783..>3834))
                     /gene="patG"
                     /product="6-methylsalicylic decarboxylase"
     gene            complement(<2810..>3834)
                     /gene="patG"
     CDS             complement(join(2810..3732,3783..3834))
                     /codon_start=1
                     /gene="patG"
                     /product="6-methylsalicylic decarboxylase"
                     /protein_id="AIG62133.1"
                     /transl_table=1
                     /translation="MAKIDVHHHFYPPAMRQALDRAGGDPSGWYIPPWTLELDQDITRQ
                     MKVTTTILSVTAPGPGIEPDVTKAAALARSCNESAAAIRDAKPQQYGFFASVPSLFDTA
                     AVLKEIEYACTTLRADGVTLFTRYGKGSNYLGHAAFRPIWADLSRRGAVVFIHPTHPVD
                     TQLINTWLPQPMFDYPHETGRAAMDLLTSGILQDYPGCKIILSHAGGTLPYLIHRAATM
                     LPLMPRTLGLSTEELVEAARTFYFDTAISSNPVTLKALFEFAAPGHVLFGSDFPNAPHD
                     AILRFTNFLEAYELPEETKRQVDSGAALELFPRLKGILDKAKL"
     mRNA            complement(<4350..>4949)
                     /gene="patF"
                     /product="hypothetical protein"
     gene            complement(<4350..>4949)
                     /gene="patF"
     CDS             complement(4350..4949)
                     /codon_start=1
                     /gene="patF"
                     /product="hypothetical protein"
                     /protein_id="AIG62137.1"
                     /transl_table=1
                     /translation="MKSSLWVSLAVSLIGLGPAAARNDYPGNYPSSSPPLGPTDWERTP
                     VSVFAKVLNTQPDPDYNLLKELVTYDCTYISLTFDNPTLHGIMPWAGTHTHVGPQAFID
                     IFTRVGLYWDRGPFSIDHIFGDDGNVTAWGSFTATSRTLGKTVISPWAARARVNSANQI
                     FEFQWMEDTFTTASSFGSDNSTKVFIANPEGGTAHA"
     mRNA            join(<5362..5739,5793..7254,7316..>7362)
                     /gene="patE"
                     /product="glucose-methanol-choline oxidoreductase"
     gene            <5362..>7362
                     /gene="patE"
     CDS             join(5362..5739,5793..7254,7316..7362)
                     /codon_start=1
                     /gene="patE"
                     /product="patulin synthase"
                     /protein_id="AIG62134.1"
                     /transl_table=1
                     /translation="MRLTSGIFHAAIAVAAVGAVLPEGPSSSKTHRNEYARRMLGSSFG
                     IPKNQTFDYLVIGGGTAGLTIATRLAEQGVGSVAVIEAGGFYELNNGNLSQIPAQDAFY
                     VGTDLDDWQPGIDWGFHTTPQAGAYDRVSHYARGKCLGGSSARNYMAYQRGTKAAHQRW
                     ADTVGDSSYTWEQFLPFFEKSLHFTPANDALRGANASVVSDPSVLGNGDGPLSVTYPHY
                     AQAFATWAKHAFIEIGLQIRSGFQSGALLGQSYGLYTINATTMHRESSETSFLRKGLAD
                     PNLTVFQSALAKRIRFQDKRAVGVDVETMGRAYTLSARKEIVLSAGAFQSPQLLMVSGV
                     GPAATLKAHNIPLVADRPGVGQNMQDHIIYAPSYRVNVITQSALLNEEFEAQANRDYNE
                     RAAGIYANPTSDILAWEKIPEPKRSAWFSNHTRQVLAEYPDDWPEVEFLTMGGYFGYQR
                     NYIRDNPSDGYNYASLAVSLCTPRSRGNVTITSPDAGVPPVINPNWLTDPVDVELAVAA
                     FKRTRDFFNTTAIKPILIGPEYFPGSQVATDAEILDHVRKSFDTIFHASCTCAMGLAND
                     TQAVVDSKARVIGVEALRVVDASALPFLPPGHPQSTLYALAEKIACEISGNC"
     mRNA            complement(join(<7640..7689,7752..7890,7984..8018,
                     8089..8511,8643..8723,8796..8908,8966..>9147))
                     /gene="patD"
                     /product="hypothetical protein"
     gene            complement(<7640..>9147)
                     /gene="patD"
     CDS             complement(join(7640..7689,7752..7890,7984..8018,
                     8089..8511,8643..8723,8796..8908,8966..9147))
                     /NRPS_PKS="Domain: PKS_ER (22-224). E-value: 1.8e-13.
                     Score: 42.1. Matches aSDomain:
                     nrpspksdomains_patD_PKS_ER.1"
                     /codon_start=1
                     /gene="patD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 246.2; E-value:
                     7e-75)"
                     /gene_kind="biosynthetic-additional"
                     /product="hypothetical protein"
                     /protein_id="AIG62135.1"
                     /transl_table=1
                     /translation="MASTTPSTYKQAVFKEQGAGLTLEEVALTLPKRDEILVKVEACGV
                     CHSDHFAQTNLMGGGFPLVPGHEIIGRVAAVGEGETVWKEGDRIGGAWHGGHDGTCGAC
                     KKGFFQMCDNEQVNGISRNGGYAEYCIIRREAAVHIPDHVNAAKYAPMLCAGVTVFNAM
                     RHMKIPPGELVAIQGLGGLGHLALQYANKFGYRVVALSRDSTKEEFARKLGAHEYIDTS
                     REDPVAALQKLGGASLIVSTAPVPEIINPLIQGLGVMGKLLILSIVGGIEVHTGLLVGK
                     GKSIWSWPSGHATDSEDAIAFADLHGIDCLIEEFPLDKCNEAFAAMMEGSVRFRAVITM
                     "
     aSDomain        complement(join(8216..8511,8643..8723,8796..8908,
                     8966..9081))
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_patD_PKS_ER.1"
                     /evalue="1.80E-13"
                     /label="patD_PKS_ER.1"
                     /locus_tag="patD"
                     /protein_end="224"
                     /protein_start="22"
                     /score="42.1"
                     /tool="antismash"
                     /translation="LEEVALTLPKRDEILVKVEACGVCHSDHFAQTNLMGGGFPLVPGH
                     EIIGRVAAVGEGETVWKEGDRIGGAWHGGHDGTCGACKKGFFQMCDNEQVNGISRNGGY
                     AEYCIIRREAAVHIPDHVNAAKYAPMLCAGVTVFNAMRHMKIPPGELVAIQGLGGLGHL
                     ALQYANKFGYRVVALSRDSTKEEFARKLGAHEYIDTSRE"
     mRNA            complement(join(<9636..10667,10723..10867,10924..>11387))
                     /gene="patC"
                     /product="MFS transporter"
     gene            complement(<9636..>11387)
                     /gene="patC"
     CDS             complement(join(9636..10667,10723..10867,10924..11387))
                     /codon_start=1
                     /gene="patC"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 304.9; E-value:
                     1.2e-92)"
                     /gene_kind="transport"
                     /product="MFS transporter"
                     /protein_id="AIG62136.1"
                     /transl_table=1
                     /translation="MSIDASPSESVLESQTPDRVDESIPIKAEETEKDAAPGRDIVGFR
                     WLLVCIAVFSANLLYGLDNTIVADIQAPIAGDFNEYTRLGWLGVGFTLGSVVFILPLGK
                     AYAIFDTKWLFLGCLTMFAAGSALCGAAPSMNAIIVGRVWAGAGGAGMYLGNLNLITIL
                     TTPKEQPVYVGLVGLIYGTGCILGPIIGGAFSDSSATWRWSFYLNLVIFGVMSPIYVFL
                     LPSLPRPAGEGRSFFKKLVELDWVGTVLSAGMHISIILFIVFGGVEWSWTDGRNIALYV
                     VSAVLTIAFVLSQYFCIGTTKQDRLFPGEFLRDPTMLLLYIIMACGGAALFVAVYYIPL
                     YFQFVHGDSGIMSAVRLLPFVCFYVATILLCGYVMPKTGYFIIWYLMSGVFMLIGAVLM
                     YTVKLDTSPSNVYGYSILMGLGMTTTQAAYAVGPAIVTPDRVAECLQFMNIGQGQSQLL
                     GLAIASAIFQTKTLSGLTALLGDKGYSQVDIQSAVAGAQSTLMERLPPALKTAALKVIV
                     SSISDVYVMAISAGALYVVASCLLPRRRF"
     mRNA            join(<12080..12193,12268..12783,12864..13286,13374..>14006)
                     /gene="patB"
                     /product="carboxylesterase family protein"
     gene            <12080..>14006
                     /gene="patB"
     CDS             join(12080..12193,12268..12783,12864..13286,13374..14006)
                     /codon_start=1
                     /gene="patB"
                     /product="carboxylesterase family protein"
                     /protein_id="AIG62138.1"
                     /transl_table=1
                     /translation="MQIINWASLLLVTWETVVAAELPIVDLGYQRHQAIGFNSTGRYYQ
                     FSNVRYAEPPLGPLRFSLPVSPRNRSHEVVNGKGLGNICPQSQACWFNVQGDFVSAVTA
                     GSTFNFTAAYDQVYQQDECTKPRPVADQNPLESEDCLFLDVYVPEKVISKRRDGNGKSN
                     PGAPVLVYFQDGAYVSGSKSDQNPSGLIATSREDGSTGIIYVGVNYRLGVFGWLSGQKF
                     QSEGGLPNAGLYDERLALEWVQRHITKFGGDPSRVTVMGVSAGGGSITMQLTAYGRAIR
                     PPFAQIIAQSPAWEPGTKTPAIEDDLLDSFLTLLNVSSLEEARRLPSQALLDANYELVA
                     SRPYGSGVFGPAIDGSFVPDSPKRLLLERKVDPSVRILTSYTANEGFMLAPANVTDDAT
                     FNRYVDVLLRGANASVRAHTSRVLYPPIFNGSWPYHSQHERANLLWSEVSTTCNTRYLH
                     QAVATPGYAIEYAVKPAMHLSDTSSVFYNGQGSSSSLNATIAQLMQRQIVQFVKTGNPN
                     VKGDPHVPLYHGQAHVLSLGDNGVRVEPALTNTDRCTYWQQVEF"
     protocluster    14613..40217
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[34612:40016]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      34613..40016
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    14613..40217
                     /SMILES="C([*])C(-O)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     mRNA            complement(join(<14650..14911,14982..15027,15109..15219,
                     15296..15491,15556..>15690))
                     /gene="patA"
                     /product="acetate transporter"
     gene            complement(<14650..>15690)
                     /gene="patA"
     CDS             complement(join(14650..14911,14982..15027,15109..15219,
                     15296..15491,15556..15690))
                     /codon_start=1
                     /gene="patA"
                     /product="acetate transporter"
                     /protein_id="AIG62139.1"
                     /transl_table=1
                     /translation="MKLSAEGTVMASSEEAAQLSCDTSSSHARNSKEQDFQPTQQIGSP
                     TALGMGAFAIAFTTLSMSLMEWRSAAITNAYIGNCFFTAGMGLVLVAQWELVRGNSFGH
                     TVFGGFGLFNLAFGAINAPAFGVADAFKDDPAALNNAIGYFLLVWGIFVLFFTVAAMPM
                     NLVYTGMLGTSQITYTLLAASYFSFADDHASAGLALKKAAGAFGFVSGLFAWYTVGHLM
                     CQDALLFSFPLGDTSPLYARLQRKKRH"
     misc_feature    complement(15952..15957)
                     /note="putative PacC binding site"
     mRNA            complement(join(<16342..16467,16538..18488,18556..18821,
                     18875..19940,20005..20245,20311..20608,20658..>20894))
                     /gene="patM"
                     /product="ABC transporter"
     gene            complement(<16342..>20894)
                     /gene="patM"
     CDS             complement(join(16342..16467,16538..18488,18556..18821,
                     18875..19940,20005..20245,20311..20608,20658..20894))
                     /codon_start=1
                     /gene="patM"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 109.4; E-value:
                     3.8e-33)"
                     /gene_kind="transport"
                     /product="ABC transporter"
                     /protein_id="AIG62140.1"
                     /transl_table=1
                     /translation="MVDNYHSSLDVAKTPIQSDADAQKSEAETEGPSSKSSQIAAGESI
                     ADSVRNFLELRQGGIPDDTGVVFDKISAVGSGTGSQDAPTVTSAAQSAFGLLSPLQNRQ
                     RKQYSRPILSGFSGTINPGEMLLVLGKPGSGCTTFLKTLSGLWDEYKEIQGELTLGGHP
                     LLDVMKQRPQDILFCAESDDHFPTLTVAETLRFATRARCGPQVSAREIDTMVTQLAKLV
                     GLGNVLNTKVGDAKIRGVSGGERRRVSLAEALATCARLICLDNPTHGLDSSTAVEFMEM
                     MREWTTQSRCVAAMSVYQASDAIVSYFDKVLIINSGRQIYYGPVRDAKAYFEDLGFECL
                     STTTVADFLNVMSADPDVRRAQENRENQVPRTAEEFERAFSASPIYQEMQKSVQVAKER
                     FQTNPSPLVKTSAFALPIWHQIWYCAGRQFRIVTSDYSLWAVELATIVVQSLVLGTLFR
                     NQQRTTSSLFIFASALFYSVLVPALQSMAEFGNGFAQRPLILKQKRYQISRPIAYALGL
                     VTTDVVWKVAAICYNIPLYFLTGFQRTAGNFFTWFLIIYLEHLALSMFFRSVAIFSPNM
                     HRAVLPVGIFFNMYVLYTGLYVPAPQMQVWLGWLRYLNPLYYAFESVMVNEFRDLSYQC
                     SASDPVPSGLGYNDMAHQVCAVVGSEPGDRLLSGASYIHAQYGFKTSHLWRNVGINAAL
                     FVFFALCSGIGMEMLKTPAGQLATVFYKSSPGVTHRRDKIDSETGQDQGNESSEMSAGQ
                     SNDALRLQEHQGPDKSHNLAWTNLCLDIKTKEGDQRLLNNLSGSVKSGQLKALMGVSGA
                     GKTTLLNALAGRSTIGNLTGTLALNGQVLPTFFRSRMGYVQQQDIHLPTQTVREALQMT
                     ARLRRPESISVADKNAYVEKVIEWLSMEHIADALVGVPGAGLNLEQRKKVSIGVEMASK
                     PEILFLDEPTSGLDGQSAMLIARLLRRLADSGQAILCTIHQPAAELIDQFDKLYLLSRG
                     GNLVYDGSLGTRCHEAIQYFQPRSRPCGPEENPAEYFLAVIGAGSRNDAHMDWASLWND
                     SEQGKEREKAEESLVPAAEQAPQLEQQSLYSVPFHVQLWVVVQRTWLYYWREPDYVNSK
                     LWMSVGNSLLNSLTHLQSPNTERGAYNRVFSAFMSLIVGPPLGLQVQPRFVTLRDIFVH
                     RERESLTYHWLAFVLSAFIVELPFTFLSSLVYWLLWYFPVGYFNAPSRAGYSFLMYELF
                     GVFATSLAQLCASLMPNIEAAFAANGFFFMFCNTFAGTLSPKPVTPSGWRWFYNISPLF
                     YLGEGVTVDVLQDLPIRCEESEVSIFYAVNGTTCGQYAQDFLKTATGYLLNPASTTECQ
                     YCRYRDGQSYFQQYGYEFAHRHRNIGVFICFIAFNFTMVLVMTYLTKTRRH"
     mRNA            join(<21354..21399,21463..21705,21759..>22249)
                     /gene="patN"
                     /product="isoepoxydon dehydrogenase"
     gene            <21354..>22249
                     /gene="patN"
     CDS             join(21354..21399,21463..21705,21759..22249)
                     /codon_start=1
                     /gene="patN"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     148.8; E-value: 3.1e-45)"
                     /gene_kind="biosynthetic-additional"
                     /product="isoepoxydon dehydrogenase"
                     /protein_id="AIG62141.1"
                     /transl_table=1
                     /translation="MVLTTGLKGAHVLITGGTRGMGEAMVHKFLQEEANVSYCARTVTN
                     TEYDDFYSTLAEGNTARAVGTAFDVASKDSLVKWVESSAERLGRIDVIIANASPMHMEG
                     ETEHWESSFAIDVMGFVELVKAATPYLEKSPQASIIVQSSFMGREFYRSPPAAYGPCKA
                     AQLQHVQELSHFLGPKGIRVNAISPGPVLCKGGPWELYSKINPEWVEEQRLKIPLKRLG
                     GPTEVANVAVFLASPLASFVSGTNMLVDGGIHVGTQF"
     mRNA            join(<22914..23173,23237..23437,23495..24451,24523..24640,
                     24694..>24873)
                     /gene="patO"
                     /product="isoamyl alcohol oxidase"
     gene            <22914..>24873
                     /gene="patO"
     CDS             join(22914..23173,23237..23437,23495..24451,24523..24640,
                     24694..24873)
                     /codon_start=1
                     /gene="patO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 310.4;
                     E-value: 5.3e-94)"
                     /gene_kind="biosynthetic-additional"
                     /product="isoamyl alcohol oxidase"
                     /protein_id="AIG62142.1"
                     /transl_table=1
                     /translation="MRLHQSPPRLLVCILSVLQVSAGLSSNCRCMPGDSCWPSLNDWAR
                     FNTSIGGRLVDTQPLGQPCHDPFYTASECNELKQQWTHPELHDASSSSIMSAAVANETC
                     DAFTPRSKPCTLGAMVRYAVNASSPDDFVQTIRFSQERNIRLVIRNTGHDYAGKSTGAG
                     ALSIWTHSLKEIDFLNYTSAHYTGPAVRMTAGIQGTDINPAAHKKGLVIVGGECATVGP
                     VGGFTQGGGHSALSSRFGLAADQVLEWEVVDGMGRLLTASPTQNPDLYWALSGGGGGTF
                     GVVYAVTVKTFPDFAVTGVVLQFENIDPSSNRFFEAVGHYHRHLPTYTSAGGMAIAQIT
                     NSSFLLTPLTLPAYTAAATKKLLGPFLQDLHQLNISYTLNVTESASYFQHYMKLIEPNP
                     TQLVQNAQYGGRLLPLDLIERNNSQLTDAVQKLTADGVTFVGIGLNVSSSVTGDIWNSV
                     LPGWRTAAMTVILTTSWPLGANLTKMKILADKMTTKWVPILTALSPESGCYMSEADPQQ
                     PDWKQTFYGRNYDSLYAIKTKYDPLQTFYATTAVGSEDWQVEAGGRLCQATRKN"
     mRNA            complement(join(<26056..28216,28273..>28511))
                     /gene="patL"
                     /product="C6 transcription activator"
     gene            complement(<26056..>28511)
                     /gene="patL"
     CDS             complement(join(26056..28216,28273..28511))
                     /codon_start=1
                     /gene="patL"
                     /product="C6 transcription activator"
                     /protein_id="AIG62143.1"
                     /transl_table=1
                     /translation="MYSTFSANFDTTIDASRDRSATPVTAPRPKRNQVARACDWCRLNR
                     VRCDDKQPCQNCQNRGGSCSNTKPQEATSLPAANREMQRLRNKVKDLQDQIAKLKEGAE
                     IQAQTGFATPPLSDAAHTSFDFAELTNTTEGWQGLQQTGQIHYGPLSSSYFVSRISRYL
                     SQALNEPIEDAKLEACMARFHYIAPSHQPSRWDASPASQADQPQDGTEEAEDLTRSQEE
                     HFLNLLWQSFHCVYPILDEREFQQYYESLWSSSPDGMSTRKPSALVDVLLAVCMQYSST
                     FFVSDDNQQGDTDSEWQAKHANLASRTYYQRAQRLLQSELENPTIMVVQSHIYSIVYLY
                     NTSLLNTAHINLGATLRIAHALRLHIRPLDGTSPEQQELQRRIWWALYRIDSQLSMTLG
                     RPPLIQLSHVSCGLPGDDREHARLSGTVLLTNHEDISWLSFHVQCTKLIFLVQGVQTAF
                     NRKCSQLLNGDKVKDLYEDPRLLETLAEFLGQEMTAIHNWVQNVPQSLCNPRKGGSDPF
                     STNRDALNLSAYSPLWLQRQRLLLELHYHHLVISTLRPFIRFPPVSSSMTPLTDGYNIS
                     CLNHAMAITSILNQVLSETDLLRGWSPIFQYQWDAILCTLGFVLANSVCPPTPSARKSL
                     QTAIRTLDLVSDHFLAAKNAAQVVREVSCQADRLVKNVQQGLTRRQAPRASQALSTRAQ
                     NPRQASNQTSFVAPAQPGVRSNSLKRALPPTTLEVSQHQPMPNFEARMQLMDMMPIGSL
                     SELSPSLGTTESMSMPSVTSADMVIGTEAQWLHASAMILDSWTTNS"
     misc_feature    complement(28921..28926)
                     /note="putative PacC binding site"
     mRNA            complement(join(<30147..30592,30726..30877,30943..31740,
                     31798..31861,31912..>32032))
                     /gene="patI"
                     /product="M-hydroxybenzyl alcohol hydroxylase"
     gene            complement(<30147..>32032)
                     /gene="patI"
     CDS             complement(join(30147..30592,30726..30877,30943..31740,
                     31798..31861,31912..32032))
                     /codon_start=1
                     /gene="patI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 202.6; E-value: 1.9e-61)"
                     /gene_kind="biosynthetic-additional"
                     /note="CYP619C2 cytochrome P450"
                     /product="M-hydroxybenzyl alcohol hydroxylase"
                     /protein_id="AIG62145.1"
                     /sec_met_domain="p450 (E-value: 5.3e-81, bitscore: 262.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDILQLAPTHLLAILLSSTSALFLITYLLRAGHRPSDLPNGPPTV
                     PLFGNELQVPKSDAHFQFSRWAKEYGGFFTLKRYNNTTIVISDQKLIKTLLDKKSNIYS
                     HRPASLVSHLITQSDHLLVMQYGERWRMLRKTIHQYFMEPRCERDHWKVQEAEAKQMLH
                     DYLTMPEDHMLHPKRYSNSITNSLVFGIRTKTVHDEYMKKLFYLMDKWSLVQELGATPP
                     VDSFALLRYVPQWMLGNWRNRAVEVGDLMQSLYQTVLDQVKERRQRGIQRDSFMDRVLD
                     TLKQTPLSENELRFLGGVLMEGGSDTSSSLILTIIQAMTKYPEVQAKAHAQIDSIIGHN
                     RSPAWSDWSKLPYINMIIKESHRWRPVSPLGVPHAVAEDDHIDGKLIPQGSSIVLNVWG
                     MHHDSDRWQEPEHFQPERFADFPALASGYAGSERRDHLGYGAGRRICPGIHLAERNLII
                     GIAKLLWAFEFLEPLGSDSDISAHSGASKGFLHCPKDYGCVIRLRSPEKRETIMREFAE
                     AQEVFARFD"
     mRNA            complement(join(<32661..33137,33194..33644,33724..>33776))
                     /gene="patJ"
                     /product="hypothetical protein"
     gene            complement(<32661..>33776)
                     /gene="patJ"
     CDS             complement(join(32661..33137,33194..33644,33724..33776))
                     /codon_start=1
                     /gene="patJ"
                     /product="hypothetical protein"
                     /protein_id="AIG62147.1"
                     /transl_table=1
                     /translation="MAPFVPYHYSAGQSTIVKFGGLLTTEFLEPPPGRCFLFRQTYRHT
                     IEGSIPENLRKLINSPDRPKGPPPHFHQFQTEYFRVENGVLGISVDGVVRRITPEDGEI
                     SVKAGSVHNFFIHPDSPENMTVYLSASDSGNDYQLDRVFFENWYGYWHDALLHDGGIDW
                     IQFLAIQDGGDAYTPAPAWVPFRRQVGYWTCVIVGRWIGGLLGYKPFFREYTTDWDFAV
                     AKMKGSFFQRHLVHAAFEEEKSWTKQAELEPKGKPENAEFEPWTEDMSPAPLSLGPVAY
                     EQGLFHGVQPGSVNGSNGHSTGVESKLEQLGSRAQRRVVIDDAGK"
     misc_feature    complement(34241..34246)
                     /note="putative PacC binding site"
     mRNA            join(<34613..34699,34773..>40016)
                     /gene="patK"
                     /product="6-methylsalicylic acid synthase"
     gene            <34613..>40016
                     /gene="patK"
     CDS             join(34613..34699,34773..40016)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (34-458). E-value:
                     1.9e-162. Score: 532.8. Matches aSDomain:
                     nrpspksdomains_patK_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (568-859). E-value: 2.4e-74.
                     Score: 242.2. Matches aSDomain:
                     nrpspksdomains_patK_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (924-1054). E-value: 1.1e-13.
                     Score: 43.7. Matches aSDomain:
                     nrpspksdomains_patK_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1410-1603). E-value: 2.8e-54.
                     Score: 175.7. Matches aSDomain:
                     nrpspksdomains_patK_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1698-1771). E-value: 3.2e-19.
                     Score: 60.9. Matches aSDomain:
                     nrpspksdomains_patK_PKS_PP.1"
                     /codon_start=1
                     /gene="patK"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 117.5; E-value:
                     9.6e-36)"
                     /gene_kind="biosynthetic"
                     /product="6-methylsalicylic acid synthase"
                     /protein_id="AIG62146.1"
                     /sec_met_domain="PP-binding (E-value: 2.7e-13, bitscore:
                     40.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6.6e-75, bitscore: 242.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.4e-163, bitscore:
                     534.5, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.7e-52, bitscore:
                     167.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MHSVSPSTYPSGGTSPAPADTPGTEYSEYEFSNDVAVVGMACRVA
                     GGNHNPELLWQSLLSQKSAVGEIPEMRWEPYYRRDPRNAKELKKTTSRGYFLDRLEDFD
                     CQFFGISPKEAEQMDPQQRVSLEVASEALEDAGIPAKSLSGSDTAVFWGVNSDDYSKLV
                     LEDLPNVEAWMGIGTAYCGVPNRISYHLNLMGPSTAVDAACASSLVAVHHGVQAIRLGE
                     SQVAIVGGVNALCGPGLTRVLDKAGAISSDGSCKSFDDDAHGYARGEGAGALVLKSLHR
                     ALLDHDNVLAVIKGSAVAQDGKTNGIMAPNAKAQQLAARTALNVAGVDPSTVRYVEAHA
                     TSTPLGDPTEISAIAGVYGTNRPADDPCYIGSIKPNIGHLEAGAGVMGFIKAILTIQKG
                     VLPPQANLTNLNSRIDWKTAGVKVVQEATPWPSSDPIRRAGVCSYGYGGTVSHAVIEEF
                     NPILRPDPLDDGAATGPGLLLLSGPQEKRLALQAKTLREWMTADGKDNNLSEILTTLAT
                     RRDHHDYRAALVVDDHLDATQVLQALANGTDHSFTTQSRVLGADVSKDVVWVFSGHGAQ
                     WPDMGKQLIHNPVFFAAIQPLDELIQAEIGLSPIELLRTGDFESSDRVQILTYLMQIGL
                     SAILQSNGITPQAVIGHSVGEIAASVVAGALTSAEGALIVTRRALLYRQVMGKGGMILV
                     NLPSAETEEILGRRQDLVVAIDSSPSSCVVAGDKDIVAETAEAFKARGVKTFTVKSDIA
                     FHSPTLNVLMDPLRDALGQALAPTVHIKLYSTALVDPRGQDVRDLEYWTGNMVNRVRLT
                     SAIQAAVEDGYRLFLEVSTHPVVSHSINETLMDAGLEDFAVIPTLLRKKPTEKHILHSI
                     AQLHCRGAEVNWAAQMPGRWATGLPTTTWMHKPIWRKIETAPLHTGLTHDVEKHTLLGQ
                     RIPVPGTDTFVYTSRLDNETKPFPGSHPLHGTEIVPAAGLINTFLKGTGGQMLQNVVLR
                     VPVAINAPRSVQVVVQQDQVKVVSRLISSDPSLSDDDASWVTHTTAYWDRKVLGSADRI
                     DLAAVKARLTTKLADNFSIDYLDKVGVSAMGFPWAVTEHYRDTKQMLARVDVNPAVLGD
                     DPLPWDSSSWAPVLDAATSVGSTVFQTAALRMPAQIERVEIFTSEDPPKISYLFVEEAS
                     DSVPTSHVSVLSETGEVLAKFTAMRFSEIEGTPGVSGSMESLVHQIAWPPATPAEEPLL
                     ITKVILVSPDATARAQYAATLPTQVQSFQFSTTEDFFSNASSLPLEKGTVVAYIPGEVA
                     SLAEVPAASESFTWNLLELIKFIVNGSLPIKVFTLTSSVGDGQTPTALAQSPLIGLARI
                     IASEHPDLGSLIDIEEPKIPLSTMRYIQGADVIRISDGIARVSRFRSLPRTKLRPASEG
                     PRLLPRPDGTYLITGGLGILGLEVADFLVEKGARRLLLISRRALPPRRTWDQVSEDLQP
                     TIAKIRLLESRGASVHVLPLDITKPDAVEQLSTALDRLSLPAVQGVVHAAGVLDNEMVL
                     QTTRDAFNRVLAPKIAGALALHEVFPPKSVDFFVMFSSCGNLVGFTGQASYGSGNAFLD
                     TLATHRARLGDSGAVAFQWTAWRGLGMGSSTDFINAELEAKGITDVTRDEAFAAWQHLA
                     KYDIDHGVVLRSLAIDDGEPVPVPILNDIVVRRVSELSGSAQAAAGSSGNDAVPSSGPE
                     LKAYLDEKIRGCVAKVLQMTAEDVDSKAALADLGVDSVMTVTLRRQLQQTLKIPVPPTL
                     TWSHPTVSHLVVWFAEKIGK"
     aSDomain        34788..36059
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_patK_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.90E-162"
                     /label="patK_PKS_KS.1"
                     /locus_tag="patK"
                     /protein_end="458"
                     /protein_start="34"
                     /score="532.8"
                     /tool="antismash"
                     /translation="VAVVGMACRVAGGNHNPELLWQSLLSQKSAVGEIPEMRWEPYYRR
                     DPRNAKELKKTTSRGYFLDRLEDFDCQFFGISPKEAEQMDPQQRVSLEVASEALEDAGI
                     PAKSLSGSDTAVFWGVNSDDYSKLVLEDLPNVEAWMGIGTAYCGVPNRISYHLNLMGPS
                     TAVDAACASSLVAVHHGVQAIRLGESQVAIVGGVNALCGPGLTRVLDKAGAISSDGSCK
                     SFDDDAHGYARGEGAGALVLKSLHRALLDHDNVLAVIKGSAVAQDGKTNGIMAPNAKAQ
                     QLAARTALNVAGVDPSTVRYVEAHATSTPLGDPTEISAIAGVYGTNRPADDPCYIGSIK
                     PNIGHLEAGAGVMGFIKAILTIQKGVLPPQANLTNLNSRIDWKTAGVKVVQEATPWPSS
                     DPIRRAGVCSYGYGGTVSHAVIEEF"
     aSModule        34788..39998
                     /complete
                     /domains="nrpspksdomains_patK_PKS_KS.1"
                     /domains="nrpspksdomains_patK_PKS_AT.1"
                     /domains="nrpspksdomains_patK_PKS_DH.1"
                     /domains="nrpspksdomains_patK_PKS_KR.1"
                     /domains="nrpspksdomains_patK_PKS_PP.1"
                     /iterative
                     /locus_tags="patK"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       35268..35315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0001"
                     /evalue="8.40E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="patK"
                     /protein_end="210"
                     /protein_start="194"
                     /score="14.9"
                     /tool="antismash"
                     /translation="GPSTAVDAACASSLVA"
     CDS_motif       35457..35495
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0002"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="patK"
                     /protein_end="270"
                     /protein_start="257"
                     /score="12.0"
                     /tool="antismash"
                     /translation="FDDDAHGYARGEG"
     CDS_motif       35688..35735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0003"
                     /evalue="5.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="patK"
                     /protein_end="350"
                     /protein_start="334"
                     /score="9.6"
                     /tool="antismash"
                     /translation="YVEAHATSTPLGDPTE"
     CDS_motif       35796..35840
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0004"
                     /evalue="6.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="patK"
                     /protein_end="385"
                     /protein_start="370"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GSIKPNIGHLEAGAG"
     CDS_motif       36384..36440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0005"
                     /evalue="2.20E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="patK"
                     /protein_end="585"
                     /protein_start="566"
                     /score="16.9"
                     /tool="antismash"
                     /translation="VWVFSGHGAQWPDMGKQLI"
     aSDomain        36390..37262
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_patK_PKS_AT.1"
                     /evalue="2.40E-74"
                     /label="patK_PKS_AT.1"
                     /locus_tag="patK"
                     /protein_end="859"
                     /protein_start="568"
                     /score="242.2"
                     /specificity="consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFSGHGAQWPDMGKQLIHNPVFFAAIQPLDELIQAEIGLSPIELL
                     RTGDFESSDRVQILTYLMQIGLSAILQSNGITPQAVIGHSVGEIAASVVAGALTSAEGA
                     LIVTRRALLYRQVMGKGGMILVNLPSAETEEILGRRQDLVVAIDSSPSSCVVAGDKDIV
                     AETAEAFKARGVKTFTVKSDIAFHSPTLNVLMDPLRDALGQALAPTVHIKLYSTALVDP
                     RGQDVRDLEYWTGNMVNRVRLTSAIQAAVEDGYRLFLEVSTHPVVSHSINETLMDAGLE
                     DFAVIPTLLR"
     CDS_motif       36612..36728
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0006"
                     /evalue="2.90E-14"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="patK"
                     /protein_end="681"
                     /protein_start="642"
                     /score="45.1"
                     /tool="antismash"
                     /translation="GITPQAVIGHSVGEIAASVVAGALTSAEGALIVTRRALL"
     CDS_motif       36822..36860
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0007"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="patK"
                     /protein_end="725"
                     /protein_start="712"
                     /score="-3.0"
                     /tool="antismash"
                     /translation="VAIDSSPSSCVVA"
     aSDomain        37458..37847
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_patK_PKS_DH.1"
                     /evalue="1.10E-13"
                     /label="patK_PKS_DH.1"
                     /locus_tag="patK"
                     /protein_end="1054"
                     /protein_start="924"
                     /score="43.7"
                     /tool="antismash"
                     /translation="HTLLGQRIPVPGTDTFVYTSRLDNETKPFPGSHPLHGTEIVPAAG
                     LINTFLKGTGGQMLQNVVLRVPVAINAPRSVQVVVQQDQVKVVSRLISSDPSLSDDDAS
                     WVTHTTAYWDRKVLGSADRIDLAAVK"
     aSDomain        38916..39494
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_patK_PKS_KR.1"
                     /evalue="2.80E-54"
                     /label="patK_PKS_KR.1"
                     /locus_tag="patK"
                     /protein_end="1603"
                     /protein_start="1410"
                     /score="175.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTYLITGGLGILGLEVADFLVEKGARRLLLISRRALPPRRTWDQV
                     SEDLQPTIAKIRLLESRGASVHVLPLDITKPDAVEQLSTALDRLSLPAVQGVVHAAGVL
                     DNEMVLQTTRDAFNRVLAPKIAGALALHEVFPPKSVDFFVMFSSCGNLVGFTGQASYGS
                     GNAFLDTLATHRARLGDSGAVAFQWTAWRG"
     CDS_motif       38919..39017
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0008"
                     /evalue="7.70E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="patK"
                     /protein_end="1444"
                     /protein_start="1411"
                     /score="47.4"
                     /tool="antismash"
                     /translation="TYLITGGLGILGLEVADFLVEKGARRLLLISRR"
     CDS_motif       39333..39440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_patK_0009"
                     /evalue="4.50E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="patK"
                     /protein_end="1585"
                     /protein_start="1549"
                     /score="54.6"
                     /tool="antismash"
                     /translation="VDFFVMFSSCGNLVGFTGQASYGSGNAFLDTLATHR"
     aSDomain        39780..39998
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_patK_PKS_PP.1"
                     /evalue="3.20E-19"
                     /label="patK_PKS_PP.1"
                     /locus_tag="patK"
                     /protein_end="1771"
                     /protein_start="1698"
                     /score="60.9"
                     /tool="antismash"
                     /translation="KAYLDEKIRGCVAKVLQMTAEDVDSKAALADLGVDSVMTVTLRRQ
                     LQQTLKIPVPPTLTWSHPTVSHLVVWFA"
ORIGIN
        1 tttttttttt ttttttttcc aaaaatcaga caagaattta ccacagaaag ctatagtaaa
       61 acctgattga gtatagataa cagttaaaaa aaagagaaaa ggaaaccacg aaaaccagat
      121 agacaacacc cgatcattcc cttcccccac cacagctcca acgacaatca gaatgcagtt
      181 gtcctgacca tcgactatcc ctcagtaaac cgagaaaaca catccgcagt cgcagtggca
      241 tattccctct caatcgtatc ccgaatgacc tcgttgcgta tcacaggtcg acaagaatag
      301 tctttggcac agtacaagaa gccattgtgg tacccagtca ccggatcact atcaatcgga
      361 ccctctcccg gctggaagtc aaacgcccac agtagtttag caattcccag gaacatgttg
      421 cgctcggcca ggtggatgcc aggacaaatc cggcgcccaa ccccgtagcc gtagtggtca
      481 cgacgctccc atgttcccgg cacatagtca ggagccaatt gaggatgttt ggcaaaccgc
      541 tcggggatga aagcagctgg gtcatcgggt tgggacggat ccatgtgcat gccccaggtg
      601 ttgactacga ctattgtgcc tttagggagg aatttgccat caacccagtc gtctataaag
      661 ataccaatgg tacagaggtt agaagatata tatcgaaagg aagaacagaa aaggagaaga
      721 aaaaagagaa gaaacaacgt accctctcct agtgcatggg ggaaacagag tggaagtata
      781 ggcctccacc ggtgaccttc cttgatgatc atgttaatat aaggaagttt ctcaaagtcc
      841 tcccaaacag gcgaccggtt gtggccgact acggcatcaa tctcagcatg tgcctttcgc
      901 tggacatcgg ggttttggat caacgcttgc acgatagcca gtgtgagact ggagctagtg
      961 tctgagcctc cttccatcag aacaccgccg ataaatgcca gctggtgcca ggggagatta
     1021 tgtttctcct ggctatccag aaccttgtcc ataaatgtgc cgttgttgtg gccatcttcc
     1081 cgtcgtttta tcactttatt aaggatatcg acgtagaggg tctccatctg cacgccgatg
     1141 gccttggctc ggtcaatata gttgttaaaa agccattgtg gcagcagttt taaccaaggg
     1201 aataggtcta ctggtggtgt tgcgccggtt tccatcacct ccgaccattc ctccatgagt
     1261 ttgtaaagtc gtcgcatatt ggctccctcc cgattggctg tgcggattcc aaatactgtg
     1321 atatgggttt agggcgtttc cggtgaataa tatatgacag acttaccgat cgagttggtg
     1381 atactgttac tgtaccgctt gggatgggcc atatgatgtt ccgggtcgat catatagtct
     1441 cgtacgagct gtatggcttc agcattgacg attttggtgt ggtggttttc caccatggtc
     1501 tccatcaggt gttggtgaac tagtcgccgg aaggtgcgcc actgatcgcc ataatgcatg
     1561 accaataggt gattaccctt tgtaatgaga tcgtgtgaga caaaggaatg gggccgatgg
     1621 ctgtagatgc cactcttgcg atcgaggact tctttgacta gtcggcgatc ggtgatgact
     1681 gccatattgc catttccgat ctttagcatg tataacccgc catactgggc ggcccattcg
     1741 gtaaacctga acgcaagaca ttagcggtga gaatttgcta tttgcttcaa aagtaaaggg
     1801 ggaggttatt gaacatactt gatatgggtg tacttcttgg taatctggtg gatgtttcca
     1861 atgaagggta gggtaggtgg acctacggtc aggtgagcaa ttcactctca gctaatttgg
     1921 aagccgaata ctcaccaata ggcatggtgc tggtccgatg gccatatgtg aaggcatatc
     1981 gtacgagcac gatggctggc aacaagacca gtagtagcag caagaatggt tccatagtta
     2041 agaggcactt atcgaggatg aactcttcag cgcttgaatt tcttcagcat cgagatgata
     2101 gtggggtatg ctgacttata gatcgacaaa gcgaggggtt catgcctatg tgcttcatgg
     2161 gattggttgt gatcaacaaa gaaattcggt tactgctcgg ttacccaaag gagtgtgccc
     2221 cggctaagat tccccaaggg gaaacacttt cctcttttct ctctgtagat ctggctcgaa
     2281 tatgatatgt catgagagtc ggttgtagag tcagctgatc atgaagggaa aagatatgat
     2341 gtcccaaaac agggcttcta atcatctcca aacagctgca ttcatcgagg ctctgatgtc
     2401 atgaacaagt agacctagag agctcgagcc ctctatttga ggggttgatt ctatggtcat
     2461 ctgagagcga gcatctgtgt ctgacacaga acccaggaag aatgattgca tcatccagaa
     2521 gagaaactga agatttggat aatctgggtg ctaggtggga catgaggttg taagaactgg
     2581 ttctgagtaa ggccacaaaa agtcccaatt gaacatccac agagatacag accataaaat
     2641 gatcgatcct tcgatgcgat aatgtgttgc aagcgaatca tgtactatta tatccatatt
     2701 gtgctatata aatgacttat agagtattgg caatatcgtt tcatcggcct tgactccaac
     2761 gctcttccaa aagcttctcg tgtacagcta gcatggaaaa tgcttcattt cagagcttcg
     2821 ctttgtccag gatccccttc agtcgcggaa acagctccag tgctgccccg ctgtcaacct
     2881 gtcgctttgt ctcttctggc agctcgtacg cctccaaaaa gttcgtgaag cgtaagattg
     2941 cgtcatgcgg ggcatttggg aagtcactac cgaagagcac atggccgggc gcagcgaact
     3001 caaaaagtgc cttcaacgtg accgggtttg atgagatagc cgtgtcaaag tagaatgtcc
     3061 gggctgcctc caccaactct tcagttgaca ggccgagcgt gcgtggcatc aagggcagca
     3121 tagtagccgc tcgatggatg agatatggca aagtcccgcc tgcatgagac agaatgatct
     3181 tgcatcccgg atagtcttgc aaaatgccac tggtcagcag atccatggcg gcccggccag
     3241 tttcatgcgg atagtcgaac atgggctgcg gtagccaggt gttgataagt tgcgtatcga
     3301 ctggatgagt cgggtggatg aagactacgg caccgcgacg gctgaggtcg gcccagatgg
     3361 gtcgaaaggc ggcatgtccc aggtaattag aacccttgcc gtagcgggtg aatagagtga
     3421 ctccgtccgc acggagagtg gtgcaggcgt attcaatttc cttcaagacg gccgccgtat
     3481 cgaataggga gggcaccgag gcaaagaagc catactgttg cggcttagca tcccgaatgg
     3541 cagcggcaga ttcattgcag ctgcgtgcca gagcggcggc cttagtaaca tcaggttcga
     3601 tacctggacc gggcgcagtg acagagagaa tggtggtggt caccttcatc tgtcgtgtta
     3661 tgtcttgatc tagctcaagc gtccatgggg gaatatacca gcccgaagga tcacccccag
     3721 cgcggtccag ggctgtttaa ggttaaccaa tgggctccca ttctaacaca gataagactg
     3781 accttggcgc atggccggag ggtaaaaatg gtggtgcaca tcgattttcg ccatgatggt
     3841 cattggggta gcactttcag tactgatcct tttgaaaacc agcacttggt gggatttacc
     3901 tgctcaaata caggtctcta gcaatggtgc ggtccatttc cgactgaatg cctgcagttt
     3961 tcccctctct cttgcatgca gcgacaacac caccttgatc gggagaccat catgaatcat
     4021 gattagagag cagtgcgtga cctctgagtg cggatcaacg gtgccgggcg aggcttgtag
     4081 gggttgcggg aactccgaag aaataccgag agagaggaag actacgcttg tacaatgcac
     4141 atcatgtcta cggatactgt ttacggaagc cccacggata tgtgcgcttg caaaatggtc
     4201 tatttcattt aaaagcgctt attcctttca ccacatcaac ccttgtccta gttcttccgg
     4261 aagaggaaat acccctccga aactccttcg gggtgatcat tttcccctgc agcaacactt
     4321 tatccttctg ctatagtgct ggatctcaat caggcatggg cggtgcctcc ctcgggattg
     4381 gcaataaaga ctttagtact attgtccgac ccaaaggatg aagcggtggt gaaggtatcc
     4441 tccatccact gaaattcaaa aatctgattg gccgaattca ctcgcgctcg agcggcccag
     4501 ggggagatca ctgtcttccc cagagtgcgg gatgtggccg tgaatgatcc ccaagcggtc
     4561 acgttgccgt catcgccaaa gatgtggtcg atggagaatg ggccccggtc ccaatacagg
     4621 cctactcggg tgaagatgtc gataaaggcc tgcggaccca catgggtgtg cgtgcctgcc
     4681 cagggcatga tcccatggag agtgggattg tcgaacgtga gggagatgta ggtgcagtca
     4741 taggtgacca gctccttcag gagattatag tcgggatccg gttgagtgtt gagcaccttg
     4801 gcgaacaccg agacgggcgt gcgttcccag tcagtaggcc caagtggtgg ggagctcgaa
     4861 ggataatttc cggggtagtc attccgagca gcggccgggc caaggccgat cagagacaca
     4921 gcgagactaa cccacaggga ggatttcatt ttgaaggtaa agctgaaact gattgcagat
     4981 ggaattgcaa tttctagcag accggtgcta gattcgacat atttatgccc ttctaccacg
     5041 agcagctcgt atccttcggc gtgattttcg ggaggaagtg ggccgttaga tgcatacttc
     5101 tcaatcatcg tccagtatta ctccgaaact cccaccgtct cctttaggta acttcttcgg
     5161 ctatgaaggc acaatacgat tccttctaac aattccccac catagtcgtc gccctaagct
     5221 gaggggaaat tcgaaggatg aaccgcgtgg agcacggcgg ccgcgctgat aagctgtgga
     5281 tttggctgtt tggaagacca aaagctttct gactccattc tgcaggcaat tcctttctgc
     5341 gacggtaatt gggacctgaa tatgaggttg acatcaggga tttttcacgc ggccatcgca
     5401 gttgctgcgg tcggcgctgt gcttccagag ggaccatcga gttcgaaaac ccatcgcaat
     5461 gagtacgcgc ggcgcatgct aggttcctcc tttggcatcc ccaaaaacca aacttttgat
     5521 tatctggtca ttggcggggg cacggccggt ttgactatcg caacgcgact tgccgaacag
     5581 ggtgtcggct cagtcgcggt tattgaggcg ggtggcttct atgagctgaa caatggcaat
     5641 cttagccaaa tccccgccca ggatgctttc tacgtgggca cggatctcga cgattggcag
     5701 cctggtatcg attggggttt ccacaccacc cctcaagcgg taagttgtcc tccccggata
     5761 atggatatca aaggctgatg aatctaaact agggcgccta cgatcgggtg agccactacg
     5821 cccggggcaa gtgcctgggg ggcagctcgg cacgcaatta catggcgtat caacgtggca
     5881 ccaaggcggc gcatcagcgg tgggcagaca ctgtggggga ttccagctat acctgggagc
     5941 agttcctgcc attcttcgaa aagagcctgc actttacccc cgcaaacgat gcgctgcgcg
     6001 gggccaatgc cagtgtagtg agcgatccaa gtgtgctggg caatggcgat ggccccttat
     6061 ccgtgaccta tcctcactac gcccaggcgt ttgcgacatg ggcgaaacat gccttcatcg
     6121 agatcggtct ccagatacgc agcgggttcc agagtggagc gctgttaggc cagtcttacg
     6181 gcctctacac gatcaatgcc acgactatgc atcgcgagtc gtcagagacg tctttcctgc
     6241 gcaaaggcct cgctgaccca aacctcacgg tctttcaatc cgccctggcg aaacgtattc
     6301 gcttccaaga caagcgggct gttggagttg acgtggagac aatgggccgt gcgtatacgc
     6361 tctccgcgcg caaggagatt gttctctcgg caggcgcctt ccaatcaccc cagttgttga
     6421 tggtctctgg cgtcggcccc gcggccacgc tgaaggcaca taatattccc ctcgtggcgg
     6481 accgcccagg cgtgggacaa aacatgcagg atcatatcat ctacgctccc tcctaccggg
     6541 tgaatgtcat cacacagtca gctctgctca atgaggagtt cgaggcccag gccaaccgcg
     6601 actacaacga acgagcagcg ggcatctacg ccaatcccac gtcagacatc ctggcttggg
     6661 aaaagatccc tgaacccaag cggtcggcct ggttctcgaa tcacacccgt caggtgctcg
     6721 ccgaataccc ggatgactgg ccagaggtag agttcctgac gatgggggga tatttcggct
     6781 atcagaggaa ctatatccga gacaatccta gtgacggcta caattatgcc tcgcttgcgg
     6841 tctcgctctg tacacctcgc tctcggggaa atgtcacgat cacgtcgccc gacgccggcg
     6901 tgccaccagt catcaacccc aactggctca ctgatccagt ggatgtcgaa cttgccgtgg
     6961 cagctttcaa gcggacgcgt gactttttca ataccactgc catcaagccc attctcatcg
     7021 ggcctgagta cttcccgggc tctcaggtcg ccacggatgc agaaattctg gatcatgtcc
     7081 ggaagagctt cgataccatt ttccacgcct cctgtacctg tgcgatgggt ctagcaaatg
     7141 acacccaggc agtggtggac tccaaagctc gagtaattgg tgttgaagcc ctccgcgtgg
     7201 tggatgcctc cgccttgccc ttcctaccac caggtcaccc ccagtccaca ctttgtaagt
     7261 cttgatcgtt ccttatacat atactgcttc aaacagaatg actaactgga ggtagatgca
     7321 ctggcagaga aaatcgcgtg cgaaatttcg ggcaactgtt agacaacggg caatatagca
     7381 tccaaccaca gggaaagatg aagaatgtta cgtagtatat agcaatcgaa gtagaagtaa
     7441 atactcaatc tatcacacct ttcacactcc atacactcca tacactccat acactccata
     7501 cactccatac actccataca ctccatacac tccatacact ccatacactc catacactcc
     7561 atacactcca ctctacgcca atactaccaa cataacaagc ataacgggca ttatccccaa
     7621 tatgtcctct acctccttac tacatggtga tgacggcacg gaaccgcaca cttccttcca
     7681 tcatggccgc tgtagaaaat aagacaccac gtcagagaca ttgaactcat caaaggaaag
     7741 agatttcata ccaaatgctt cgttgcactt gtccaagggg aattcttcta tcagacaatc
     7801 aatgccatgg aggtcggcaa acgcgatggc gtcctcggaa tcggtggcat gaccgctggg
     7861 ccagctccag atggatttac cctttccgac ctacactata attagtacct tcatttcttg
     7921 atcttgccat catctcttcc gtttgcgttt ctgcttgatt tcagagagga aaatcccact
     7981 taccagcagg ccagtgtgca cctcaatacc accaacaact attattgtca gcatccaatc
     8041 aaaattccag gaagcataat ttttcaagaa caagccaaga gagcttactg gacagaatca
     8101 acaacttccc cataacacca agtccctgaa tcagcgggtt aataatctca ggcacaggcg
     8161 ccgttgacac gatcagagaa gcaccaccca gtttctgcaa agcagcgacg ggatcctccc
     8221 gactggtgtc gatgtactca tgtgctccta gcttccgtgc aaattcctcc tttgtggagt
     8281 cccgcgagag cgccacgacg cggtagccaa acttgttcgc atattggagt gctagatggc
     8341 cgagtccacc cagaccctgg atggcgacca gttcacccgg tgggatcttc atgtggcgca
     8401 ttgcgttgaa gacggtgaca ccggcacaga gcatgggtgc gtatttggct gcattgacgt
     8461 ggtctggaat gtgtacggcg gcttcgcggc ggatgataca atattcggca tctaccggaa
     8521 ttggagagga ggggttagca ttgagatatt atttttttcg gtggaacgag gaaatggtga
     8581 taaaaaaaga aaagggtgat aataaaagaa gagagagaag taaagaaagg agaaagacat
     8641 acagccgcca tttcgggaaa tgccgttgac ttgctcatta tcgcacatct ggaagaagcc
     8701 ctttttgcat gccccgcagg tacctgttaa gtgcatcagt gtatattctc gtcaaggaat
     8761 cagactcttt tgtagccgag aaaagaattt cataccatcg tgcccgccat gccatgcacc
     8821 tccaattcga tctccttcct tccaaacggt ctcgccctct ccgacagctg ccacacgtcc
     8881 aataatctca tgaccgggaa ctagcggact ataaaatcac cgggaattag gcaaagtgtc
     8941 atatatttca cgataggtgg ctcacaatcc tcctcccatg agattcgtct gcgcaaagtg
     9001 gtccgaatga cacacgccgc aggcttcgac tttgaccaaa atctcatccc gcttgggtag
     9061 agtcaatgca acctcttcta gggtcaggcc ggcgccttgt tccttgaaga ccgcctgctt
     9121 gtaggtgctg ggagtagtgg aggccatggt gcgtattctg ctgaataata gatagctgtg
     9181 cgaagtaaga ctatgtttct gcgtcggagg gaggggatgc ggggagaaga ttagataaat
     9241 atttctttgg cctctcctta tctactagta caaggtggga tgcggagtcg gagttccgga
     9301 gactactata ttggctcatt ggcgtatccc gaggtcaaag taacaaatgt tgatgataaa
     9361 cctccttcag ctggataagc ccttatccac tatatttgaa acgtggagat ttctcaggtg
     9421 ttatatttta ttctatctcc cgaagatatt ttgattccac tggctaggta aattatgatt
     9481 tataaacaaa aaagagcaaa ggatacatct caaggcgtac ctcgagctca aaaaggacaa
     9541 gaagaaaaga aaccccatta ccaaatacac cccagtcacg gatccaaagc cagtatcccg
     9601 tttgccattg gtgctatcct tcccgtggaa cggatctaga accgacgacg aggcagcagg
     9661 caggatgcaa ccacgtagag agcacccgcc gaaattgcca tgacgtagac atcactaatc
     9721 gaactcacaa tcaccttcag ggctgccgtc ttcaaggccg ggggcagtcg ctccatcagg
     9781 gtactctggg cgccagcgac ggcactttgg atgtccacct gcgaatatcc cttatctccc
     9841 aacagggcag tgagcccact gagggtcttg gtctggaaaa tggcactggc gatggccaat
     9901 cccagaagct gactctggcc ctggccgatg ttcatgaact ggagacattc ggccacgcgg
     9961 tcgggagtca caatggctgg acccaccgcg taggcggcct gtgtagtagt catgcccagt
    10021 cccatcagga tggaatatcc gtagacgttg gaggggctgg tatccaattt cacggtgtac
    10081 atcaacacgg ctccaatgag catgaagaca ccactcatga gataccagat gataaagtag
    10141 ccggtcttgg gcatgacata accacaaagc agaatcgtag ccacgtagaa gcagacgaac
    10201 ggcaacagac ggactgccga catgatgcca gagtcgccgt ggacgaactg gaagtagagt
    10261 gggatataat aaactgccac aaagagggcg gcaccaccac aggccatgat gatatagagg
    10321 aggagcatcg tggggtcacg caggaactcg ccggggaaca gtcggtcctg tttggtggtc
    10381 ccgatgcaga agtactggct gagcacgaaa gcaatggtga ggacagcgga gaccacgtac
    10441 agagcgatgt tccggccatc tgtccaggac cattcgacac caccgaagac gatgaacaag
    10501 atgatggaga tgtgcattcc tgcggaaagg accgtgccca cccagtcaag ctccacaagc
    10561 ttcttgaaga agctgcggcc ttcgcccgct ggtcgtggca aggagggcag gaggaataca
    10621 tagatgggtg acatgactcc aaagataacc aagttgagat agaatgactg tcattgcggt
    10681 cagcataccc ggccagagaa acgagcaagg gatcacacgt acccatcgcc atgtggcaga
    10741 actgtcagag aaagcaccgc caatgatagg acccagaata cagccagtgc cgtagatcaa
    10801 tccaaccagg ccgacataca caggctgctc cttgggggtg gtcaggatgg taatcagatt
    10861 cagatttcta tgtttcttgg tcagccctca atctctgatc tcggcctgtc acgataaact
    10921 taccccagat acatgcccgc tccaccagct cctgcccaca cacgcccgac aatgatggca
    10981 ttcatactag gagcagcacc gcagagagca ctgccagccg caaacatagt caaacagccg
    11041 aggaagagcc atttcgtatc gaagatggcg tatgctttgc ccagcgggag aataaagacc
    11101 accgatccca aggtgaagcc cacaccaagc caacccagcc gcgtgtactc gttgaagtca
    11161 ccggcaatgg gagcctggat atcagccaca atggtattat ccaagccata gaggaggttt
    11221 gcagagaaaa cggcaatgca gacgagcagc cagcggaagc ctacgatgtc ccggcccggg
    11281 gctgcatcct tctcggtttc ttcagctttg atcgggattg attcatccac gcgatccggg
    11341 gtttgacttt cgagcacgct ctcacttggt gaagcgtcta tactcattgt gggaagcgaa
    11401 ccgagcggca cttagtcagc tgttttagag gttcagctat ctaggcactt gcccaatgga
    11461 gtcgtagtaa agtgaaaata gaaggcagca atatagttat ccactggagg acgttggcga
    11521 aagtattgat gtcccatatt gcccgaccgt gcctggttat ttaaatgcta gcagtgctgg
    11581 aagaggacat tttggtgaca atgcattact cctttcggac attcatcttt gtcagtgtgg
    11641 tatctgacca atcgtagctt accatttgac tgaccaactc cgaatctcct ttcggactcg
    11701 gagcgggagt acccgagctc acctaattct aataattaag tgggtccgtc tggacctgca
    11761 tccatggatc cgctcttcaa tttctaagcg ttttcagcat ttccaaggtt tcaaaaattt
    11821 caaccttggg tcgtgattag ctataataca accctagaaa tgtagatcag ccctgcccag
    11881 agattacttc gtaaacggaa tttatatgga acccctttga gccatctttt acagttgcta
    11941 ttttattcta gttagagggt ttttgcgcac gacattagct taacatatgc tacctataaa
    12001 taaatgcaaa acagtaaaaa tgctagatag tgaaatacaa aaaacctggg agctcattat
    12061 accccataat tcattcccaa tgcaaattat caactgggcc agtctgctac tggtcacatg
    12121 ggagactgtt gtagcagccg aattgccgat tgtggacctg ggctatcagc ggcatcaagc
    12181 cattggcttt aacgtgagtc ccataccgcg aaaaagaaat gaaaggctta gaaatccatc
    12241 tgatgatcag ctcaatgata tacctagtcg actggtcgct attaccaatt ttctaatgtc
    12301 cgttatgccg aacccccgtt aggccccttg cggttttccc tgcccgtctc cccacgaaat
    12361 cgcagccacg aggttgtcaa tggcaagggg cttggcaata tctgtcccca atctcaagcc
    12421 tgttggttta atgtgcaggg cgactttgtc agtgccgtga ccgcgggctc gacttttaat
    12481 ttcaccgccg cgtatgatca ggtctaccaa caggatgaat gcaccaagcc gcgaccggtc
    12541 gcagaccaga atccactgga gtcagaagat tgtctgttcc tcgatgtgta cgtcccagag
    12601 aaggtgatat ccaaacgacg agatggaaac ggaaaatcga atcctggtgc gcccgtctta
    12661 gtgtacttcc aggatggagc ctatgtgtcc gggtccaagt cagatcagaa tccctccggc
    12721 ttgatcgcaa ccagcaggga ggatgggtcc acaggcataa tctatgtggg cgtcaactat
    12781 cgagtacgtg gctctccctc tctttcccgt gcaaattcgt ctccttttct ttcagcggct
    12841 tatccaggga tggtatcgac tagctgggcg tatttggatg gctgtcaggt cagaagtttc
    12901 agtcggaagg gggcttgccc aacgccgggc tgtatgatga gcgtctggcg ttagagtggg
    12961 tgcaacgaca tatcacgaaa ttcggcggtg atccctcacg cgtcactgtc atgggcgtct
    13021 cagccggcgg gggctcaatc acgatgcaac tgacggccta cggacgcgcc attcgccccc
    13081 cgttcgccca aatcattgcg cagagtccgg cttgggaacc gggcacaaag acaccggcta
    13141 ttgaggacga cctgttggat tcattcctta cattgttgaa tgtcagcagc ttggaggagg
    13201 cccggcgttt accatctcag gccttgctag atgctaacta tgagctggtg gcgtcccgtc
    13261 cgtatggttc tggtgtgttc ggaccggtaa gtactatccg agctatttgc tgccattccc
    13321 cgttcatcat ttctttgaat actgattgaa caatcttctg ctcatcacta taggccattg
    13381 atgggagctt tgtacccgat agtcccaagc gactcctcct tgagcgcaag gtcgatccct
    13441 ctgtgcgaat cctcacctca tacactgcca acgaagggtt tatgttagcc ccagccaatg
    13501 tgaccgatga tgccaccttt aaccgatacg tggatgtgct gctccgcggt gcgaatgcta
    13561 gcgtacgcgc tcacacctcc cgagtgctct acccacccat cttcaatggc agctggccgt
    13621 atcacagtca gcacgaacgg gccaatctac tctggtccga ggtctctacc acctgcaaca
    13681 cccggtattt acaccaagca gtcgcaacgc caggctatgc gattgagtac gctgtgaagc
    13741 ccgcgatgca tctctcggat acctcatctg tcttctacaa tggacagggt tccagctctt
    13801 cgctgaatgc caccatcgca caactcatgc agcggcagat cgtgcagttt gtcaagacag
    13861 ggaatccaaa tgtcaaggga gatccccatg tacctctcta tcacggacaa gcccatgtgc
    13921 tttcactggg agataacgga gtgcgagttg agccggcctt gactaataca gaccggtgca
    13981 cttactggca gcaggtcgag ttttgatgaa ctcagtaggg gaactgaact tatctcaaag
    14041 cgcgtttcag ctcgagttaa tgatcattca tactcctatc ggatatcata tctagtagag
    14101 actaatgctc atccaaaata tactattgag aaagcttgtt aatctcccta aggcagacca
    14161 tattgaaaaa cgcagttgac tctcattatt taccacgtag ttggggttgt ttcaactcta
    14221 tttctaatca caaccctaat cggcccattc atataccatc ttcagcatac aaggttactg
    14281 tccccaatgc aaagtgggat taagtcagct gtttctatat ccatggatgt ttctatacat
    14341 gtagagaata acgggctgtg aacaggggta gaaggaaaag aaaagtccgt agatagagat
    14401 ctatcacccg gaaatgaaga tatcacacat ctttttacaa ttatgactgt gtactaaggt
    14461 gttggcaaac accttgcaac acataattct agcaatatat ttcgtaacgc catagcttcc
    14521 attgaatatc gtaataatct tgtaccacat aatcaacatg acatcccata gctcactcgt
    14581 ccacctgcac cactaggtcc ctcgaaatta ttccatccct caaaatctca atctcttacc
    14641 cacgatgctt cagtgtctct tctttcgctg caatcgtgca tacaagggac tcgtatcccc
    14701 cagtgggaac gagaatagga gggcatcctg acacatcagg tggccgacgg tgtaccaggc
    14761 aaacaaccct gagacaaacc caaatgcacc cgcggccttt ttcagagcga gtccagcaga
    14821 tgcatgatca tctgcgaacg agaagtacga ggcggccaac agagtgtatg taatttggga
    14881 agttccgagc atgcccgtgt acaccaggtt cctgtctacc agtcagctat gaccacgctt
    14941 tcagacggga tatctgtata tataaatgtg tatcaactga catgggcatt gcagcaacgg
    15001 taaagaagag aacgaatatc ccccatacta tatcgtcgtg ttagccgaaa tcccacctaa
    15061 aacaaaagaa aagatgacaa gaaaaatccg tttgcagaaa gaactcaccg agcagaaaat
    15121 atccaatggc attattcaat gccgcgggat catctttgaa ggcatctgct accccaaagg
    15181 ccggtgcatt gatcgcgcca aaagctaagt tgaacagacc tggatgggag cccgatgggt
    15241 cagatcacgg ccatcatgca cggcaaatca taggatgaag taactagatg ctcaccaaag
    15301 cctccaaaga cggtatggcc aaaggaattc ccgcgcacaa gctcccactg ggccaccaat
    15361 accaaaccca tgccagctgt aaaaaagcag ttaccaatat aggcattggt gatggctgcg
    15421 cttcgccact ccatgagact catcgataga gtggtgaaag caattgcgaa tgcacccata
    15481 ccaagagcag tctggtagca gtcatggata gttagatgat gtttcaactg ggagtctaaa
    15541 tacagggcac tttactggac tgccaatctg ctgggtgggc tggaagtctt gctctttgct
    15601 atttctagca tgagaggacg aggtatcaca gctcaactga gctgcctcct ccgaggaggc
    15661 cataacagtt ccctcagctg atagtttcat cttgtagcac gttgggtcgg caaaagtggt
    15721 tatagttgaa tcagaaaaaa gaccacagtg tgaggaaaag agggcttcta atttagaatc
    15781 aagttgtcag cacttaaact tgcctgaaga aacaggggta taaatacgcg catgtctgtc
    15841 ccgcattcgc aggtcaacaa acgctaaatt cttggtagcc aaagtttctt ggtataatat
    15901 cctgttctga cttactccat ggagaagtgg gtgctgatct tcccaaacca gcttggccaa
    15961 ggaatccaac ccctcatact agtgatttcc taccccctca tgctggtatg attccatttc
    16021 cccattgagc tgtattctga aaactgacgg tctgcagaaa gatcatcgac aagtcggagg
    16081 gggaggggca gtgaatgtca tgccatgtct attggcagaa ggtcagagca gagcctgcaa
    16141 ataagataag gagactacaa cataggatcg ggctcatacg ctagagattc aaagagaaat
    16201 agctcattcg gattatattt ctctactatc tcagttttct ttctactctt tctactatcg
    16261 aacaagaaac cttggaaatc atccccaaaa ttaagtccct cctatagcct ggatccaccg
    16321 cagactatca tatatcttcc atcaatgacg acgcgttttg gtgagatagg tcatcacgag
    16381 aaccatggtg aaattgaacg cgatgaagca gatgaaaacg ccaatattgc ggtgccgatg
    16441 agcaaattca tagccgtatt gttggaacta tcaaatggtt ggtttccaga ttagatatgt
    16501 tgccttgaat tcctttgtcc tgataaaaac tacttacgta tgattgtccg tcgcgatacc
    16561 gacaatattg acactccgtc gtgctcgctg gattgagcaa atatcccgtg gcggttttca
    16621 ggaaatcctg ggcgtactgg ccacaggtag tgccattcac cgcgtaaaag atcgaaacct
    16681 ccgattcctc gcatcggatg ggcagatctt gcaaaacatc cacggtgacg ccctcgccta
    16741 ggtagaagag gggagagata ttataaaacc aacgccaacc tgaaggtgtc actggctttg
    16801 gcgaaagcgt tcccgcgaag gtgttacaga acatgaagaa gaatccgttg gcagcaaagg
    16861 ctgcctcgat gttgggcatt agcgatgcgc acagctgagc cagactggtg gcgaagactc
    16921 caaagagctc gtacatgagg aagctgtatc ctgcgcgtga gggggcgttg aaatagccaa
    16981 cagggaagta ccacagcagc caatatacca gcgagctgag gaacgtaaag ggcagttcca
    17041 cgataaatgc agataagaca aatgccagcc agtggtaggt caagctctca cgctcccggt
    17101 ggacgaaaat atctcgcagg gtcacgaagc gtggttgcac ctgcagccct agtggggggc
    17161 ccacgatgag tgacatgaaa gcagagaaga cccgattgta agcccctcgc tccgtgttag
    17221 gagactgtag gtgggtgagg gagttgagga gggagttgcc gacgctcatc cagagcttcg
    17281 agttgacata atccggttct ctccagtaat acagccaggt tcgctgaacc accacccaca
    17341 gctgcacatg gaacggtacc gaatacaacg actgttgctc cagctgtggt gcttgctctg
    17401 cggcggggac caagctttct tccgcctttt ctcgctcctt gccctgctcg ctgtcattcc
    17461 aaagactggc ccaatccatg tgggcgtcat tgcgagaccc agccccaatc accgcgagga
    17521 aatactctgc tgggttctcc tctgggccgc aggggcgact ccgtggctgg aaatactgga
    17581 ttgcctcgtg gcagcgggtt cctagggaac cgtcatagac taaatttcct ccacggctca
    17641 gcagatacaa cttgtcaaac tgatcgatga gctcggctgc cggttgatga atcgtacaca
    17701 ggatggcttg gcccgagtct gctagacgac gaagcaagcg agcgatcaac atggcggatt
    17761 ggccatcgag acccgaggtc ggttcatcga ggaagagaat ctctggtttg gatgccatct
    17821 ccacgccaat actgactttc ttccgctgtt caagattgag gccggcaccc gggacaccaa
    17881 ctagggcgtc ggcaatatgc tccatactca accactcaat cactttctcg acgtaggcat
    17941 tcttgtctgc tacggagatg gactctggtc gtcgaagtcg tgctgtcatt tgcaatgcct
    18001 cgcgcacggt ctgagtggga agatgaatat cctgctgttg tacgtagccc attcgacttc
    18061 ggaagaatgt tggcagcact tgaccattga gcgctagtgt tccagtgaga tttccgatgg
    18121 tggaacggcc agcgagtgca ttcagtaggg ttgtcttgcc ggcacccgag acacccatca
    18181 gagccttgag ctgaccactc ttgactgaac cactcagatt gtttagcaga cgttgatcgc
    18241 cctccttggt tttgatgtcg agacagaggt tggtccatgc aagattgtgg ctcttgtcag
    18301 gaccctgatg ttcttgtaac cgaagtgcgt cattgctttg gccagctgac atctccgaac
    18361 tttcattccc ttggtcttgt cctgtttcgc tatcgatttt atcacggcgg tgtgttacgc
    18421 ccgggctgct cttgtagaac acggtagcca attgacccgc gggtgttttc agcatctcca
    18481 tcccgattct gttcaaattt cagtgtcagt cttggacttt ctctttggac taggcttcag
    18541 tgcatgatta cttacccaga gcaaagggca aagaaaacaa atagggccgc gttgattcca
    18601 acattcctcc agaggtgaga ggttttgaat ccgtactgag catgaatgta cgacgctcca
    18661 gacaggagac gatctccagg ctctgatccc actacagcac agacctgatg ggccatgtcg
    18721 ttatatccca aacccgatgg gaccggatcc gaggcactgc actggtaact caggtctctg
    18781 aattcattca ccatcactga ctcaaacgca taatataagg gctgtcatat gttagcataa
    18841 cttatccaaa cctcatggta cagtctccac taacatttag atatcgcaac cacccgagcc
    18901 atacttgcat ctgtggtgcg ggcacgtaga gccccgtgta taggacatac atgttgaaga
    18961 aaatacccac cgggagcacg gcccgatgca tgttgggaga gaagatggct actgagcgaa
    19021 agaacattga gagggcgaga tgctccaggt agatgattag gaaccaggtg aagaagttcc
    19081 cagccgtccg ctgaaatcca gtcaggaagt atagggggat attatagcag attgcggcca
    19141 ccttccacac gacgtccgtg gtgaccaaac cgagcgcgta ggcaatcggg cgagagatct
    19201 ggtatcgctt ttgtttcaag atgagtggtc tctgggcgaa cccattacca aattcagcca
    19261 ttgactgcag ggcagggacc aggacagagt agaacaaagc agatgcgaaa ataaacaggg
    19321 aactggtcgt tcgctgttgg tttcggaaca gcgtgcctag caccagactt tggacgacga
    19381 tggtggcgag ctctaccgcc cacaagctat aatcactggt tacaatgcga aattggcgac
    19441 cagcacagta ccaaatctga tgccagatag ggagagcaaa agccgatgtt ttgactaggg
    19501 gactggggtt ggtttggaat cgctccttgg ccacctgaac cgacttttgc atctcctggt
    19561 agatggggct ggcactaaac gcacgctcaa actcctctgc agttcgtggg acctggtttt
    19621 ccctgttttc ctgggctcgt cgcacgtctg gatcagcgga catcacattg aggaagtcgg
    19681 caacggtggt ggtcgataaa cactcaaatc cgagatcttc aaaatatgcc tttgcgtccc
    19741 ggactgggcc atagtagatc tgacgaccag aattgattat gaggactttg tcaaagtagg
    19801 agacaattgc atcactggct tgatagacgc tcatcgcggc cacacatcga ctttgcgtcg
    19861 tccactcgcg catcatctcc atgaattcga ccgccgtgga tgagtccagt ccatgggttg
    19921 ggttatccag gcagattagg ctgtgggaat gtatgagttg atgaatcatc attggtatat
    19981 actggagcag aagagatcac ttaccgggca caggtggcca gggcctccgc caaagacact
    20041 cgccggcgct ctccgccact gactccccga atcttcgcat ctcctacctt ggtatttagg
    20101 acattcccaa gaccaactag ctttgccagc tgagtaacca ttgtgtctat ttcacgggcc
    20161 gagacttggg gaccgcagcg cgctctggtc gcaaagcgca gggtctctgc cacggtcaat
    20221 gtagggaaat gatcatcaga ctcggctaag ggaggcattt ctatcagtgt gtgttcaaaa
    20281 gaaccaaaca gaaaaagcgc gaggacttac cgcagaagag aatatcttgg ggccgctgtt
    20341 tcatcacatc tagcagtgga tgaccaccca gagtgagttc tccctggatc tccttatatt
    20401 catcccacag ccccgacaga gttttcagaa aggttgtaca tccactcccg ggtttaccta
    20461 gcaccaacaa catttctccg gggttgattg tgcctgagaa tccgctgagg atgggtcgag
    20521 agtactgttt tctttgtctg ttttgcagag gactcaacag cccgaaggcc gactgggccg
    20581 ccgacgtgac ggtgggtgca tcttgcgact atcaacagtt agtcgagatg ctttcagttg
    20641 gagtcagtgg tacttactcc tgttccactc cccactgctg atattttgtc aaagaccacc
    20701 ccggtatcat cgggaatgcc tccctgacgc agctcaagga agttcctaac actgtctgca
    20761 atcgattccc ctgctgcaat ttgagacgat ttcgacgacg gtccttcggt ttcggcctca
    20821 gacttttgag catcggcatc ggactggata ggtgtctttg ccacgtctaa cgacgaatga
    20881 taattatcta ccattatgaa gataggcaaa gttgcaatac tatcacaacc ccttcattaa
    20941 ccaagaatca cattgccgac tagaaaatgt ggaaatggac gagttcaaaa ggacatcaaa
    21001 acaatagctc atctcctgtt cctcctttcg ctgtccaatc tagatatatc gtgagtttcc
    21061 taaaggagtt acggagtttc cagacagtcc caatcgggta agtgttctgg gccaactttc
    21121 aacgtgtggc ccgagggaga atgcgaaggt gaatggccta gcgtatctct ccaagggtct
    21181 tagagccaat gattatttcc aatctataaa gcaaatgctg cgaactccga agggggccgg
    21241 aacctatttc gccgctttca agtctcttta ttcgatctgt tttctacttg ttcccattcc
    21301 catttacatt ccaatttcaa tttcaatttc aattttcaaa tttattgaca atcatggttc
    21361 tcacaactgg tctcaaaggc gcccatgtgc tcatcacagg taagaagaat caagatcaag
    21421 aaaaaaacat acctagttgt gtccgactaa cgcgggaact aggaggcacg cggggtatgg
    21481 gagaagcaat ggtccataag ttcctccagg aggaagccaa tgtatcctac tgtgctcgaa
    21541 ccgtcaccaa taccgagtat gatgacttct actcgaccct cgctgaggga aataccgccc
    21601 gcgctgtagg cacggcgttc gatgtcgcta gcaaagattc cctcgtcaag tgggtcgaga
    21661 gctccgccga gcgactcgga cgaattgacg tgattatcgc taatggtgat tgattttctt
    21721 agaatttctt atttaaaatg tgtactgact ggtcgcagcc tcgccgatgc atatggaagg
    21781 cgagacggag cactgggaga gcagtttcgc gatcgatgtc atgggtttcg ttgagctggt
    21841 caaggcggct actccctact tggaaaagtc cccccaggca tccatcatcg tgcagagctc
    21901 tttcatgggg cgggaattct accggtcccc tccggcggcc tacgggccct gcaaggcagc
    21961 gcagctgcag catgtccagg aactgtccca cttcttgggg cctaagggca tccgcgtcaa
    22021 tgccatctcc ccaggaccgg tcctgtgtaa gggaggtccc tgggagctgt attcaaagat
    22081 caacccggaa tgggtggagg aacagcgatt gaagattcct cttaagcgtt tgggagggcc
    22141 gacagaggtg gcgaatgtgg ctgtgttcct ggcgagtccc ctggccagct ttgtgtcagg
    22201 cacgaatatg ttggtcgatg gtggaattca tgttggaacc caattttaga ttttagaact
    22261 gagaatgaga ccaatgatat tgtagttttt ttaagatgat aatacttttt ttcttccggc
    22321 aagaatgtct aaaacagtat tccccttcaa cgtagaaaag gagggagact acatagggaa
    22381 gcccacatag ctgttcaagg aaaaatgacg agattggtct agacaatgct ggttctggaa
    22441 gactctgatc caacttcccg aaaggttgtc tcaagtcgct cctagtctcc acaagtatga
    22501 taggaccgga gtcagcatct cggagcctga aaggtatcat gcacaaagat gtcatggatc
    22561 atgcaggtaa tacgagttga gaggttgagt gtcgtctttt aggatctaca tctcactcta
    22621 gtaaacccaa aataggtcag agaaaatacc ggagatcaac gagaacccac tgtaaacaac
    22681 aagctggggc tatatcggca gccatcggag atagaatgca ctccctctct catcaggact
    22741 tccaagcaat atgcacatcc catctagtgc gggggtcggg cagctggatg ctattttcat
    22801 gattccgagg aattggcggt aacgaggagc tactgggaga actataagaa tatgctcctc
    22861 ggccacagcg tagtacacaa atcaattaga tctgctagat agcaggcttc aaaatgcgtc
    22921 ttcatcagtc cccacctcgc ctcctggtgt gtatcttgtc tgttctccag gtttccgccg
    22981 gtttgtcttc aaactgtcga tgcatgcctg gtgatagttg ttggccgtcc ctgaatgact
    23041 gggcacgctt caatacgtct attggcggac gactagtgga cactcaacca ctaggacagc
    23101 cctgtcatga tcccttctat accgccagcg agtgtaatga gctaaagcag cagtggacgc
    23161 atccagagct ccagtaagta atccaattca tccaacgagc tcggtggctg acctgttgaa
    23221 acactccatt caatagcgat gcatcctcct cttccataat gtcagccgcc gtggccaatg
    23281 aaacttgtga cgcctttact ccccggtcaa aaccatgcac actgggtgcg atggtgcgct
    23341 atgcggtcaa tgccagctct ccagacgact tcgttcaaac catccgattc tcccaggaac
    23401 gaaacattcg tctggtaatt cgcaacacag gccatgagta tgaatcatcc ggtatctata
    23461 gataacatgt accctcgcta atgatgtatc ctagttatgc cgggaagtca acaggtgcag
    23521 gcgcactatc catttggacc cattctctca aggaaatcga cttcttgaac tacaccagcg
    23581 cacactatac cgggcccgcc gtgcggatga ccgccggcat tcagggaaca gacattaacc
    23641 cggccgctca taagaaaggg ctggtgatcg tgggcgggga atgtgctact gtaggccccg
    23701 ttggtggttt cacacaagga gggggccact ccgccttgag ctctcgattc ggccttgcgg
    23761 ccgaccaagt cttggaatgg gaagtggtag atgggatggg acgattgctg accgcatcgc
    23821 ctacccagaa cccggatctg tactgggctc ttagcggagg tggaggaggg acatttggcg
    23881 tcgtgtacgc cgtgactgtc aagacattcc ccgactttgc cgtcacgggt gttgttcttc
    23941 aatttgagaa tatagacccc tcgtcgaacc gtttctttga agcggtagga cattatcatc
    24001 gtcacctgcc tacatacacc tcggctggtg gaatggcgat tgcacaaatt acaaactcgt
    24061 ccttcttgct tacaccgctg acacttcctg cgtataccgc agcagcgacc aagaagctgc
    24121 tcgggccgtt tttgcaggac ctgcaccaac tgaacatatc ctataccctg aacgtcaccg
    24181 agtccgcctc gtatttccag cattatatga aactgatcga gcccaacccg acgcaactgg
    24241 tgcaaaatgc gcaatatggc ggtcgtcttc tccccctcga tctcatcgag cggaataact
    24301 cgcagcttac ggatgccgtc cagaagctca ctgcggatgg ggttacattc gtgggaattg
    24361 gtctgaatgt ctcgtcatct gtgacgggag atatctggaa ttcggttttg cctgggtggc
    24421 gtacagcagc gatgactgtg attttgacca cgtacgctct ctttttccgg catgctgggc
    24481 aacttctttg tttttatatg cttgctgaca cctataatcc aggagctggc ccctcggtgc
    24541 caacctcacc aagatgaaaa ttctggcaga caaaatgacg accaaatggg tacctatcct
    24601 aacagctttg agtccagagt cagggtgtta tatgagcgag gtaaggagag acgtattcat
    24661 aatttggaga cgactggcta actgtacaaa caggccgatc cccaacagcc agactggaag
    24721 cagacctttt acggtcgcaa ctacgattca ctttacgcga tcaagacgaa atatgatcca
    24781 ctccagacat tctatgctac aacggctgtt ggcagtgagg actggcaagt cgaggctggt
    24841 ggtcgtctgt gccaggccac cagaaagaat tgacacgacg agatactgtg gaaataagga
    24901 ctaaaatttt ggaatttcct ataggccttg tgggaccata caatagagat agcatcttag
    24961 ggccgaattg gatatcaggg aactcaggcc tctagacatg atttccttca taggtagagt
    25021 aatgggggca tcgaaaagtc ccccaacaga aacccttttg ggtttgacaa aagaacagac
    25081 tgcttctcgc ttgcttacaa ttaaaatcat cccattgaaa ccccgaattt gatagtacat
    25141 aagtgaaaaa tagctcaagt acggagtaga tggtgctttt gtgcaaaagg ctccaccttg
    25201 tacgtactat cttacgtctg caatgccgat cctagtacta gataagactg ggataacaat
    25261 tcctcttgtc attgggtgtt gtcataggga cttagggaca gatcggccta aatttgctct
    25321 gtgaacaatg tgagcgagtg gagacctaaa cctaacatca ttgcgttatg gtttctagta
    25381 agagtgtctg atcgagctgg acgagccacg atggtggcat gtaacaaagc taggactgta
    25441 attgtttatc tgatggtgta ttcaaaggga aagtgcatct agcaatctat attcctattg
    25501 actcgtagta tctgggttat tttatatgcc aaatatgtga acgcacctcg atataaattt
    25561 atcggactga caacttaagc gaccccgaat cttccaaaga gtcctagttt ccctgggtaa
    25621 ggagcaagta gaccatgtag tatattattc aaggtatgcc cgctggtcgt tacatggaag
    25681 atatgttcca aggtccatta aggagaactg atattccgac aatttacagt gaagcttgaa
    25741 acattcgagg caagatgtca tgggaaattc aattggataa cgctatcacc tattctaggt
    25801 tctaatccga aaagcatagg gcccatccgg tacatacacg tgcatatgta caataaataa
    25861 gttatcgatc cagttcgtgt cttctatttc tctccaccta gcagggcccg ctgcatggtt
    25921 atatactatg gattagattt agagagggcg gtactctaag tcggacaaaa tgtaaaatca
    25981 gcaagacaaa acatcaacag tgaaagaagg aaaaaaaaaa aaaaaaaaaa tgaaagaaaa
    26041 aaggaaaacg gttaatcatg agttcgtggt ccaggaatcc aggatcatcg cactggcatg
    26101 tagccactgg gcttcagtgc cgatgaccat gtcagcagac gtgaccgagg gcatcgacat
    26161 agactctgtc gtccctagag aaggagagag ttccgataat gacccaatgg gcatcatgtc
    26221 cattaattgc atgcgcgctt caaagttagg cattggctga tgttgtgaca cctccagggt
    26281 agtcggtggc agcgcccgct tgagtgagtt ggaccggacc cccggttgcg cgggggcaac
    26341 gaacgaggtt tgattcgacg cctgcctggg attctgggcc ctggtggaca aagcctggct
    26401 ggcacgtggc gcttgtcgcc gggtcagacc ttgttggacg tttttgacga gtcgatcggc
    26461 ctggcaactg acttcgcgga cgacctgcgc cgcatttttg gctgccaaaa agtgatcact
    26521 cacgaggtcc agcgtgcgaa tcgccgtctg cagcgacttg cgggctgaag gggtcggtgg
    26581 gcagactgaa ttggcaagca cgaatcccag ggtacatagg atggcatccc actggtactg
    26641 gaagatgggt gaccagccgc gcaggagatc cgtttcagac agcacttggt tcaggatact
    26701 ggtgattgcc atggcgtggt tcaaacagga gatgttgtaa ccgtcggtca gtggggtcat
    26761 ggaagagctc acgggaggga atcgaataaa gggacgcagt gtcgagatca caagatggtg
    26821 ataatggagc tccaggagga gacgttgacg ctgcagccag agcgggctat acgcagacag
    26881 attcagcgcg tcccgatttg tggagaaagg gtcactgccc cccttgcgag gattacatag
    26941 tgactgcggc acattttgga cccagttgtg aatggctgtc atctcctgtc cgagaaactc
    27001 ggccaaagtc tcaaggaggc gcgggtcctc atatagatcc tttaccttat ccccgttcag
    27061 caactgggaa catttccggt tgaatgctgt ctgcacgccc tggacgagaa atatgagttt
    27121 cgtgcattga acatgaaagc tgagccagct aatgtcctca tgattcgtga ggaggactgt
    27181 gccagatagc cgggcgtgct cgcgatcatc tcccggtagc ccgcagctga catgggacag
    27241 ctgaatgagg ggcggccgac ccagggtcat cgagagctgg ctgtcgatcc gatagagcgc
    27301 ccaccaaatt cggcgctgta actcctgctg ctcgggggac gtcccatcca gcgggcggat
    27361 atgtaaccgc agcgcgtggg cgattcgcag cgtggcaccc aggttaatat gtgccgtatt
    27421 cagcagggag gtgttgtaca agtatacaat cgaatagatg tgactttgaa cgaccatgat
    27481 ggtggggttt tcgagctcac tctgcagaag cctctgggcc ctctggtagt aagttcgact
    27541 ggccagattc gcgtgtttgg cctgccattc agaatctgta tccccctgct ggttgtcatc
    27601 actgacgaag aacgtgctgc tgtactgcat gcacactgcc aacagcacat cgaccaaggc
    27661 ggatggcttc cgggtggaca ttccgtccgg agaacttgac cataatgact cataatattg
    27721 ctgaaattcg cgttcgtcga ggatagggta tacacagtgg aaggactgcc agagcagatt
    27781 gagaaagtgt tcctcttgtg agcgggtcag atcctcggcc tcctcggttc catcctgagg
    27841 ctgatccgcc tggctggccg gacttgcatc ccatcgagac ggttgatggg acggggcaat
    27901 ataatgaaag cgtgccatgc atgcctccaa ctttgcatct tcgattggct cgttaagtgc
    27961 ttgggagaga tatcgactga ttcgggagac aaaatatgag gacgacaagg gcccgtagtg
    28021 aatctgccct gtctgctgga ggccttgcca tccttctgta gtattggtga gctcagcaaa
    28081 gtcgaacgag gtgtgagcag catccgacag tggtggcgtc gcgaaacccg tctgtgcttg
    28141 gatttccgct ccttctttga gtttcgcgat ctgatcctga aggtccttga ctttatttct
    28201 taatcgttgc atttctctat cgatgtggat cagcaggccg tttacgttca tcccgatgtg
    28261 atggtttcct accggtttgc agctgggagc gaggtagcct cctgtggctt cgtattgctg
    28321 caagagcctc ctcgattctg acagttctga catggctgct tgtcatcgca tctgacacga
    28381 ttgagcctac accagtcaca agcccgagcg acctggttac gctttggtcg tggagctgta
    28441 acaggcgtgg ctgatctgtc acgggaggcg tcaatcgtgg tatcgaagtt ggcggagaaa
    28501 gtggagtaca tgacggaggc gtggggtgga gggacaaaac aaatcagata ttcattcaga
    28561 ccagtttcgt tcgactccaa atggcggtcg gaaccttaaa aggaatttcc ctctgggcta
    28621 ctcaagactt gacggggggg aggggtcgga ggggggcgcg gttgatcgcg taaaggaaaa
    28681 aagagttgcg caggagtggt gttggcgttg gatgcctgag gtttcagatg tctgggcaaa
    28741 ccgacaaaga caaaagtaca taacaaaatg cagggatgat gggctccccc tgcacaaaat
    28801 gagacttgca tgaaaagacc aagaagggaa taaaacacga gaaaacagcg ggatactagc
    28861 tacactaggt aggtacaact cttataattc gtcagctatt gtcagctatt atcgcgcatc
    28921 cttggctgaa ttcgccactt cgctttgttg gaataataag cgagtctgat ggtatcattg
    28981 gtccgaagtc agaaagataa gatattagac ctcgcaaggt tggaccctta tagccaccaa
    29041 ggttagagtg gccagggaat ctcatcctac tgggtatata caacatagac gagagacttt
    29101 acgaacctac aaatcttgcc cagatttttc caagtattga tgagaaagct tagctgtata
    29161 ttggtagaat atatagggat cgacgtctat attgccaagg tagagagtac actagtgcta
    29221 taagcaatat ataatcctag ttattacaga tcgaattatt catgcattga aggaatatat
    29281 attgactaat cgggaaaggc attcagaaat tatggagaaa aggaacacag tataatgaat
    29341 atcataaatc aaatcacctc aaatcacatc acatcctagc gtgagtccta tactcctatc
    29401 aatcagcgct agagggattc ttcacgatta cgattcttca ccccacgtcc tatctagaca
    29461 ctatgaactc caattaagcc ccaaaggcgt gctagggcga tcatcttatc tacaaattaa
    29521 gatccaatct ttcggggatc tttgaaggag tcggagtgag gtccgccgtt ccgctgctcc
    29581 tctcggcgac atgcatctgc tgcagaaacg gagttggcat tatgatctta cacgaatgcg
    29641 atttgcatca atgtacaggg attcagatcc tttacaaggt gaagtgtccg aattgcctat
    29701 tttaggtacg atgtagtagc catatggtaa taccaatatg cactaacaat tataattgca
    29761 cgtggaatcg gaacaaagtc tgggtttacg gaacacaagg ttaccttgcc gctttcccgg
    29821 gccttatgaa ctaaactcct acgccgttgg aggcaaaaat acccaatgga ttgacgcgtg
    29881 ggatgcaaaa tgcatgtcag aatccgggac gctacaccaa tcgggggttt caactaaatt
    29941 aaatccctcc acatgaaaaa catacttcat tgattaataa acggatacgg aagatctgca
    30001 acaaaatagg gttttgatgc cgagctagca tacatagtag catggataat ttcaccggac
    30061 cttcgcaaaa atattccaaa tggaggctgg tgataacagg gggaggaggg tagcgatcac
    30121 attctagcgt ttatcctcta atctagctaa tcaaatcgag cgaacacctc ttgcgcctcg
    30181 gcaaactccc gcataatggt ctctcgcttc tccggagacc gaagacgaat gacacagcca
    30241 tagtccttgg ggcaatggag aaacccttta ctagcgccgg agtgagctga aatatcacta
    30301 tcgctaccga ggggttcgag gaattcaaag gcccagagca acttggcaat gccgatgatc
    30361 aagttgcgtt ccgctaagtg gatgcccgga cagatgcgcc ggcccgctcc gtaaccaagg
    30421 tggtctcggc gctcggatcc agcgtaaccc gaggcgagcg ctgggaaatc agcgaagcgt
    30481 tcaggctgga aatgttctgg ttcttgccat cgatcactgt catgatgcat gccccagaca
    30541 ttgagaacga tactcgatcc ttgcggaatg agtttgccgt cgatgtggtc atctgaggtg
    30601 gatcgttagc caagatcttc tgggtttggt tcctgatttt ctttttcatc tgtgtcatct
    30661 gcaagaacta caagaactgt aataactgct tggcgcaggc aaaataaaaa tggattcaaa
    30721 cacaccttca gcgacggcat gtggaacacc caatgggctg acgggacgcc accggtgaga
    30781 ttctttgata atcatattga tatagggcag cttggaccag tcagaccaag ccggggagcg
    30841 gttatggccg ataatggagt cgatttgtgc atgtgctctg caataccacc ctattagctt
    30901 tctcgcttaa acagattagg atggaaggcc cggtcggcat acttggcctg aacttccgga
    30961 tatttagtca tggcctggat gatcgtcaat ataagcgagg acgaagtgtc ggagcctcct
    31021 tccatcagga ctccccctag gaatcgtagc tcattctcgg agagtggggt ctgttttagt
    31081 gtgtctagaa cccgatccat aaaagaatcg cgctgaatac cccgctggcg gcgctcctta
    31141 acctgatcta gcacggtctg atacagcgat tgcattaaat cacccacttc aactgcccga
    31201 ttccgccaat tacccaacat ccactgtggc acatagcgca gcagagcaaa tgagtcgaca
    31261 ggcggggtag cgccaagctc ctgcaccaag gaccatttgt ccatcaggta gaatagtttc
    31321 ttcatgtact catcgtggac agttttggtt cgaatgccaa agacaagcga gttggtgata
    31381 ctgttactgt accgcttagg atgcagcatg tgatcctcgg gcatggtgag atagtcatgc
    31441 agcatctgct tggcttctgc ctcctggacc ttccagtggt cacgctcgca gcggggttcc
    31501 atgaaatatt gatgaatggt tttacgtaac atgcgccatc gctctccata ctgcatgacc
    31561 aagaggtggt cgctctgcgt gataaggtgg gataccagcg atgctggtcg gtgggagtat
    31621 atattgctct tcttgtccag cagtgtcttg atcagtttct ggtcgctgat gacaatggtg
    31681 gtgttgttat atcgtttcag cgtgaagaaa ccgccatact cctttgccca cctggaaaac
    31741 ctacattaat cacttagcat gctacccagg tacaaccaca ggggagtttc tctttactga
    31801 aaatgtgcat cagactttgg aacctgcagt tcgtttccaa acagtggaac ggttggagga
    31861 cctgtgcatc tgttaaatgt gaaacgccac ctttttgttg cgacaacata ccgttcggga
    31921 ggtctgaggg tctatgtcct gcacggagga gatatgtgat gagaaacaat gcgctggtac
    31981 tgcttagcag tattgccaga aggtgcgttg gtgcgagctg taagatatcc atagcgttga
    32041 tagatggccg gaaagtgcgc ctcaaaatgt acttactgtc tatacttatg gtcttcattc
    32101 acgcggggaa atggtatgat acctatttta agattttggg acagtttggg ttcctaaagg
    32161 agaatcggag tctgctcgta tagatctctc aaggctgaaa acatcttctg tgcttacatc
    32221 ccgtcctatc ctgggtatta tcgatgaagc gtctgtaaga cccttcgaaa tgtgatctga
    32281 actttacctg aatggacggt tgggcgtcaa gtattagcta catgcttcag ggatacaagc
    32341 tcagatgcca tattagcgcc tgatttacga tgagcaactc ctctatgttt gatggtctac
    32401 gtgaaaagag gaattattat ggacagggtg tataagaact ataagaaata tagtgctgat
    32461 gacagccacg tgaagtcatg tgttctttcc ctccagatca tcgtaacctt gctgtttctc
    32521 tctaaacaga tctcagtata gacagccagt gaaaatccca tcgtgtacta gtcatactca
    32581 agaatcaaga gtgaaaatac caaatgaatt caaatggact atgattcata aactaacagg
    32641 tgctgggaaa ttacccatct ctacttgccc gcatcgtcga tcactacccg ccgctgtgcc
    32701 cgagagccta gctgctccaa cttgctctcg acccctgtag agtgaccgtt ggatccattc
    32761 acagaccctg gttgtacccc atggaataga ccctgctcat acgccactgg gcctaagctc
    32821 aatggggcgg gggacatatc ctccgtccac ggctcaaact cagcattttc aggcttaccc
    32881 ttaggttcca gctctgcctg cttcgtccag gatttctcct cctcgaatgc ggcatgcacc
    32941 agatgccgct ggaagaagga acccttcatc ttggcgacag caaagtccca atccgtagta
    33001 tattcccgga agaagggctt atatcctagg agtcctccaa tccatcggcc gacaatcaca
    33061 caggtccagt atccgacctg ccggcgaaag gggacccacg cgggagcagg tgtataggca
    33121 tctccgccat cttgaatcta cgaccatgtc agacaagggc aagggggatc gtgcacctag
    33181 aattaattct taccgcgagg aactggatcc aatcaatccc tccgtcatgc aacaatgcat
    33241 cgtgccaata gccgtaccag ttctcgaaga agacccgatc gagctggtag tcattcccgg
    33301 agtccgatgc actcaggtag acagtcatgt tctcgggaga atctgggtga atgaagaaat
    33361 tatgcacact acccgccttg accgagatct cgccatcttc tggggtgatg cgacggacaa
    33421 cgccgtccac cgagataccg agtactccat tctcgacgcg gaagtactca gtttgaaatt
    33481 ggtgaaaatg cggcggcgga ccctttggtc gatcgggact gttgatgagc ttgcgcaggt
    33541 tctctgggat cgatccttca atagtatggc ggtatgtctg gcggaagaga aaacaacggc
    33601 ctggtggagg ttcgaggaat tcggtggtga gcaagccacc aaatctagat gacgggtcta
    33661 tatcagcgac caaaaagccc cttgccccga taatcaggac ggaaaaagga gccaattaca
    33721 tacttaacaa tagtcgactg gccggccgag tagtggtatg gcacaaacgg agccatcgtt
    33781 gttgtgatgc ttgaaggttg gccaactggt aaaaatctga ttttacagca gagtcataaa
    33841 tattggatct cttcttctaa agaatacgta aaagcacccc agtgtctcta ctagcacata
    33901 tatacttgat agctatctta tttgactggg cttcttccat gcagagttcc ccatctgcct
    33961 gttgaaccat gtcaaaatgg cctgatcaaa acttggggta tctttagttg tgcatcttct
    34021 cctcctccgg agtatttgca cggagttccc atgagctccc taaagggtgt agtatctcat
    34081 ctaagacctt ttgaagaaat aatccccggc actcctttcg gttaatcagc atgcatcccg
    34141 ttcaggctta gggctgacgg caggatgccc tcaatgtttc aaatcccgga taacgcagtc
    34201 gggatcgcca ttgccaatgc ttacgggtgg gggtaaaatc cttggctcct atctatagat
    34261 cccgttgtcc gtgagtgaga ctcgttcttg cgaagcttgt gcgtattatg gcgtgcagcc
    34321 cgaacagtat ccccgaacgg gcgaatggac gaagataaag atgacccaat tgggacgctg
    34381 gaccgcagcc gatgttgcta ctgctgattt tccttgtgaa tggtctggat gtcggccttt
    34441 ccgggacgat aaggaaccct cgtggaggag ggggtagggg aaggatttgc agatatcgta
    34501 ttggagaacg agaggtataa aggagcatcg acaaccggca gctgggaaca ttttcatgaa
    34561 taagcttgac attgctaagg agattgcgtc tccgaactgc tactgtcaaa acatgcattc
    34621 tgtttcgcct tctacatacc cctctggggg aacatcccca gcaccagctg atactcctgg
    34681 tactgagtac agtgaatatg tttgtggtcc caatccccga cggtttacat cgtcgtctgc
    34741 cacaagtgta ccttgggact gacaatcaat aggaattctc caacgacgtg gccgtggttg
    34801 gaatggcctg ccgcgttgcg ggaggaaacc acaaccctga gctcctctgg caatcgctcc
    34861 tcagccagaa aagtgcagtg ggtgagattc cagagatgcg ctgggagcct tactatcgtc
    34921 gggacccacg aaatgcaaag gaactcaaga agacgacgtc gcgtggttat ttcctcgatc
    34981 gcttggagga ctttgattgt cagttcttcg gcatctcccc taaggaggcc gagcagatgg
    35041 atccccaaca gcgagtctca cttgaggtgg cctcagaggc actggaggat gccggcattc
    35101 ccgccaagag cctgtctggg agtgacacag cagtcttctg gggtgtaaac tcagacgact
    35161 actccaagct agtgctggag gatctgccaa atgtcgaagc ctggatgggc atcggcaccg
    35221 cgtattgtgg cgtgcccaat cgcatttcct atcacctgaa cctgatggga cctagcaccg
    35281 ccgtggatgc ggcctgtgca tcgtctctcg tcgccgtcca ccatggagtt caagccatcc
    35341 ggctgggcga atcacaggtg gcgattgttg gaggtgtcaa cgccctctgc ggaccaggcc
    35401 tgacccgcgt cctcgacaaa gctggagcta tctcatctga tggatcttgc aagtcattcg
    35461 atgatgacgc ccatgggtac gctagaggcg aaggcgccgg cgccctcgtc cttaaaagtt
    35521 tgcaccgtgc attgctcgat catgataacg tcttggccgt tatcaaggga agcgcagtag
    35581 cccaggatgg caagacaaac ggcatcatgg cccccaatgc caaagcacaa cagctagcgg
    35641 cgcgaactgc tctcaacgtt gcaggagtcg accctagcac tgtgcgctat gtggaagccc
    35701 atgccacatc tacacccctg ggcgacccaa ctgaaatatc cgccatcgca ggcgtgtacg
    35761 gcaccaaccg ccccgccgac gatccatgct acatcgggtc catcaagccc aatattggtc
    35821 acctggaagc tggtgcaggc gtcatgggct tcatcaaagc aatcctgacc attcaaaagg
    35881 gtgtcctgcc tccccaggcc aacttgacaa atctcaatag ccggattgac tggaagacgg
    35941 ctggcgtgaa ggtcgtccaa gaggccaccc cgtggccctc ctcggacccc atccgtcggg
    36001 caggtgtttg ctcgtatggg tacggaggta ccgtttctca cgcagtaatc gaggagttca
    36061 atcctatcct gcggccagac cccctggatg atggtgcagc caccggacca ggccttttgt
    36121 tgctgtcagg cccccaggag aaacggttag ccctgcaggc taaaaccctg cgtgagtgga
    36181 tgactgccga tggaaaggat aataatctga gtgaaattct cacgacattg gctacgcgac
    36241 gagatcacca tgactaccga gcagcgcttg tggttgacga ccatctcgat gctacccagg
    36301 tcctgcaagc actggctaat ggaaccgacc attccttcac gacccagagt cgcgtattgg
    36361 gcgcagacgt cagcaaggac gttgtctggg tgttttccgg gcacggtgcg cagtggccgg
    36421 acatgggcaa gcaactaatt cacaatcctg tattcttcgc agccatccag ccactcgatg
    36481 agctgattca agccgagatt ggcctgtccc ccatagagct gctccgcacg ggcgactttg
    36541 agtcgtcgga tcgggtgcaa atccttacct atctcatgca aatcggtctc agcgccatcc
    36601 ttcagagcaa tggaatcact ccacaggccg tgattggcca ctcagtgggc gaaattgcgg
    36661 ccagtgttgt ggccggggct ttgacttcag cagagggcgc gctcattgtg acccgccgag
    36721 cgttgttata ccgacaggtc atgggcaagg gcggcatgat ccttgtcaac cttcctagtg
    36781 ccgagaccga agagatctta ggtcgccgac aggacctggt tgtggccatc gattcatcgc
    36841 cttcgtcctg cgtggtggct ggagataagg atattgtcgc cgagacagca gaagccttca
    36901 aggcacgggg tgtgaaaaca ttcaccgtta agagcgacat tgccttccac agtccaaccc
    36961 tgaatgtcct tatggatcct ctgcgagatg cgctcggaca ggctctggcc cctacagtcc
    37021 acatcaagct gtattccacc gcactggtcg accctcgcgg ccaggacgtg cgcgacttgg
    37081 aatactggac cggcaacatg gttaaccgcg tgcgtctcac ctcggccatc caagcggccg
    37141 ttgaggacgg ataccgcctc ttccttgaag tctcaaccca tccagtggtg tctcactcca
    37201 tcaacgagac gctaatggac gcaggcttgg aggatttcgc agtcatccct actcttctac
    37261 gtaagaagcc gactgagaag catatcttgc acagcattgc acagcttcac tgccgcggcg
    37321 cggaagttaa ctgggcagcg cagatgcctg gacgctgggc tactggattg cccactacca
    37381 cctggatgca taagcccatc tggcggaaga tagagactgc gcccctccat actggcctca
    37441 cgcacgatgt cgagaagcac acccttctgg gacaacgcat cccagtaccc ggcaccgaca
    37501 ccttcgtcta cactagccgc ctagacaacg aaacaaagcc tttccctggc agtcatcccc
    37561 tacacggcac cgagatcgtt cccgcagcgg gtctgattaa tactttcttg aagggcaccg
    37621 gcggccagat gctccagaac gtggtgctcc gcgttcccgt tgccatcaac gcgccacggt
    37681 ctgtccaggt cgtggtccag caggatcagg tcaaggtcgt gtcccggctg atttcgagtg
    37741 atccctcgct gtcggatgac gatgcctcct gggtcactca caccactgct tattgggatc
    37801 gcaaggttct gggttccgca gatcgcatcg acctcgcggc cgtcaaagcg cgactgacca
    37861 ccaaactagc agacaacttc tcaattgact acttggacaa ggttggcgtc tcagccatgg
    37921 gattcccatg ggcggtaaca gagcactacc gtgataccaa gcagatgctg gcgcgcgttg
    37981 atgtcaatcc cgctgtcctt ggagatgacc ccctaccctg ggattcttcc tcctgggccc
    38041 cggttctcga cgctgccacc tctgtcggtt ctaccgtctt ccaaacagct gcgctgcgga
    38101 tgccagccca gatcgagcgc gtggagatct tcacctcgga ggacccgccc aagatcagct
    38161 acctcttcgt cgaggaggcc tctgattcag tgcccacctc tcacgttagc gtgctgagcg
    38221 agacgggtga ggtccttgct aagtttacgg ctatgcgctt ctccgagatt gaaggcaccc
    38281 cgggtgtcag tggcagcatg gagagtctcg tgcaccagat cgcctggcca ccggcaaccc
    38341 cggctgaaga gcccttgctc atcacgaagg tgattctggt ctcgcccgat gctaccgcgc
    38401 gggcccagta tgccgcgacc ctgccgaccc aggtgcagtc cttccaattc tcaaccacag
    38461 aggacttctt cagcaacgct tcatccctcc ccctcgagaa gggaaccgtt gtggcctaca
    38521 tccccggtga ggtcgcctcg ctggcagagg ttcccgctgc atccgagtcg ttcacttgga
    38581 acctgcttga gctgatcaaa ttcatcgtca atggttcact gcccatcaaa gtcttcactc
    38641 tcacttccag cgtgggcgat ggtcaaacac caaccgccct ggcccagtcc ccattgatcg
    38701 gtcttgcacg aatcatcgcc agtgagcacc ccgatctagg atccctcatc gacattgaag
    38761 agcccaaaat ccccctgtcg acgatgcgat acatccaggg ggccgacgtc atccgtatca
    38821 gcgacggaat cgcccgcgtc tcccggttcc gcagtctacc acgcaccaag ctgcgccctg
    38881 ctagcgaggg tcctcgcctg cttccccggc ccgatggcac atatctcatc actggcggtc
    38941 tcggaattct cggactcgag gtcgctgact tcctggtgga gaagggcgcc agacgtctgc
    39001 tgctcatctc gcgacgtgct cttccgccgc gccgaacttg ggatcaggtc agcgaggatc
    39061 tccagccgac catcgccaag atccgcctct tggagagtcg cggcgcctca gtccacgtcc
    39121 ttcccttgga catcaccaag ccggatgcgg ttgagcagct gtccacggcc ctagaccgcc
    39181 tctccctccc tgcggtccaa ggtgtcgtcc acgctgccgg cgtcttggat aacgagatgg
    39241 tattgcagac cacgcgtgac gcctttaacc gggttcttgc gccgaagatc gcgggtgcgc
    39301 tagccctgca cgaagtcttc cctcctaaga gtgttgattt ctttgtcatg ttctcctctt
    39361 gtggaaacct agtcgggttc actggccaag cctcttacgg cagtggcaac gccttcttag
    39421 atacactggc cacccaccgg gcacgcctgg gcgactcggg agctgtggcc ttccagtgga
    39481 ctgcatggag gggccttggt atgggctcca gcacggactt cattaacgcg gaattggaag
    39541 ccaagggaat cacagacgta acacgcgatg aggcctttgc tgcctggcag catcttgcca
    39601 agtatgatat tgaccacgga gttgtcttgc gaagtctcgc cattgatgac ggggagccgg
    39661 tgccggtgcc catcctcaat gatatcgtgg tgcgacgcgt gagcgagctc tctggcagcg
    39721 cgcaggcagc tgctggctcc agtggcaacg acgcggtgcc ttcctcagga ccggagctca
    39781 aggcgtatct ggatgagaag atccgcggct gtgtggccaa ggtgttgcag atgacagctg
    39841 aggatgtgga ttcgaaggca gccctggctg atctgggtgt tgactctgtc atgacggtca
    39901 ctttgcgtcg ccagttacag cagacgctga agatccccgt gcccccaaca ttgacgtgga
    39961 gtcacccgac tgtcagtcat ctggtggttt ggtttgccga gaagattggc aaatgattga
    40021 cctccattcc atccggtcag tagaaggtcg atgattatga tgcttgatat tgtttcttat
    40081 tgtcttttcc atgtctttat ttatgtttca tccttttgta ttcctttttg aatatttcga
    40141 gatccttagt tattagactg tttgaaatat acttttttat gttctccttg aaaaaaaaaa
    40201 aaaaaaaaaa aaaaaaa
//
