BGC0000125: pimaricin biosynthetic gene cluster from Streptomyces natalensis
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 84,985 nt. (total: 84,985 nt).
This entry is originally from NCBI GenBank AJ278573.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000125
Short description pimaricin biosynthetic gene cluster from Streptomyces natalensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AJ278573.1
via
Compounds
  • pimaricin
Species Streptomyces natalensis [taxonomy]
References
Chemical products information
pimaricin Evidence:
Copy SMILES
C33H47N1O13
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAC20917.1
 2 - 2086 (+) hypothetical protein
    copy AA seq
    copy Nt seq
    • CAC20918.1
    • pimK
    		 2190 - 3566 (+) PimK protein
      copy AA seq
      copy Nt seq
      • CAC20919.1
      • pimS4
      		 3662 - 9736 (-) PimS4 protein
        copy AA seq
        copy Nt seq
        • CAC20920.1
        • pimS3
        		 9772 - 15198 (-) PimS3 protein
          copy AA seq
          copy Nt seq
          • CAC20921.1
          • pimS2
          		 15210 - 43733 (-) PimS2 protein
            copy AA seq
            copy Nt seq
            • CAC20922.1
            • pimI
            		 43924 - 44691 (-) PimI protein
              copy AA seq
              copy Nt seq
              • CAC20923.1
              • pimJ
              		 44909 - 45940 (-) PimJ protein
                copy AA seq
                copy Nt seq
                • CAC20924.1
                • pimA
                		 46283 - 48091 (+) PimA protein
                  copy AA seq
                  copy Nt seq
                  • CAC20925.1
                  • pimB
                  		 48069 - 49949 (+) PimB protein
                    copy AA seq
                    copy Nt seq
                    • CAC20926.1
                    • pimE
                    		 49964 - 51613 (+) PimE protein
                      copy AA seq
                      copy Nt seq
                      • CAC20927.1
                      • pimC
                      		 51702 - 52760 (+) PimC protein
                        copy AA seq
                        copy Nt seq
                        • CAC20928.1
                        • pimG
                        		 52789 - 53985 (+) PimG protein
                          copy AA seq
                          copy Nt seq
                          • CAC20929.1
                          • pimF
                          		 54038 - 54229 (+) PimF protein
                            copy AA seq
                            copy Nt seq
                            • CAC20930.1
                            • pimS0
                            		 54309 - 59852 (+) PimS0 protein
                              copy AA seq
                              copy Nt seq
                              • CAC20931.1
                              • pimS1
                              		 60759 - 81152 (-) PimS1 protein
                                copy AA seq
                                copy Nt seq
                                • CAC20932.1
                                • pimD
                                		 81418 - 82611 (+) PimD protein
                                  copy AA seq
                                  copy Nt seq
                                  • CAC20933.1
                                  • pimH
                                  		 82859 - 84157 (-) PimH protein
                                    copy AA seq
                                    copy Nt seq
                                    Biosynthesis information
                                    Annotation changelog

                                    Entry version: 4

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-10-07
                                    Update chemical activity to schema version 2.11
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 3

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-09-15
                                    Updated bioactivity data
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 2

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2019-10-16
                                    Migrated from v1.4
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 1

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2015-06-12
                                    Submitted
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    Detailed domain annotation
                                    Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                    A domain glossary is available here, and an explanation of the visualisation is available here.
                                    Selected features only
                                    Show module domains
                                    Similar known gene clusters from MIBiG 4.0
                                    Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                    Click on reference genes to show details of similarities to genes within the current region.
                                    Click on an accession to open that entry in the MiBIG database.