Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000126.1:
Cluster 1Polyketide174342

BGC0000126, pladienolide biosynthetic gene cluster from Streptomyces platensis. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: pladienolide
PubChem ID: 44568919
SMILES string: Copy to clipboard
Molecular formula: C30H48O8
Average molecular mass: 536.706 Da

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:
Type I

Gene cluster description

pladienolide (BGC0000126). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank AB435553. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Machida K et al. (2008) Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107. Biosci Biotechnol Biochem 72(11):2946-52. doi: 10.1271/bbb.80425. Epub