BGC0000126: pladienolide B biosynthetic gene cluster from Streptomyces platensis
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Location: 1 - 74,342 nt. (total: 74,342 nt).
This entry is originally from NCBI GenBank AB435553.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000126
Short description pladienolide B biosynthetic gene cluster from Streptomyces platensis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB435553.1
Compounds
  • pladienolide B
Species Streptomyces platensis [taxonomy]
References
Chemical products information
pladienolide B
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C30H48O8
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAH02268.1
  • pldAI
 8340 - 27938 (+) polyketide synthase
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  • BAH02269.1
  • pldAII
 28021 - 49101 (+) polyketide synthase
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  • BAH02270.1
  • pldAIII
 49134 - 60272 (+) polyketide synthase
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  • BAH02271.1
  • pldAIV
 60269 - 65695 (+) polyketide synthase
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  • BAH02272.1
  • pldB
 65707 - 66906 (+) cytochrome P450
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  • BAH02273.1
  • pldC
 66967 - 68160 (-) putative acyltransferase
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  • BAH02274.1
  • pldD
 68267 - 69568 (-) putative epoxidase
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  • BAH02275.1
  • pldR
 70017 - 72725 (-) transcriptional regulator
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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