BGC0000133: quartromicin A1 biosynthetic gene cluster from Amycolatopsis orientalis
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Location: 1 - 82,338 nt. (total: 82,338 nt).
This entry is originally from NCBI GenBank JF970188.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000133
Short description quartromicin A1 biosynthetic gene cluster from Amycolatopsis orientalis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
JF970188.1
via
Compounds
  • quartromicin A1
Species Amycolatopsis orientalis [taxonomy]
References
Chemical products information
quartromicin A1 Evidence:
Copy SMILES
C77H102O30
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFI56998.1
16990 - 17736 (+) regulatory protein
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    • AFI56999.1
    17733 - 18476 (-) short chain dehydrogenase
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      • AFI57000.1
      18587 - 19438 (+) alpha/beta hydrolase protein
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        • AFI57001.1
        19443 - 20369 (-) hypothetical protein
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          • AFI57002.1
          20640 - 22055 (+) propionyl-CoA carboxylase
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            • AFI57003.1
            22078 - 22833 (+) thioesterase
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              • AFI57004.1
              22952 - 23920 (+) 2-oxoacid dehydrogenase, acyltransferase
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                • AFI57005.1
                23935 - 41709 (+) QmnA1
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                  • AFI57006.1
                  41706 - 47021 (+) QmnA2
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                    • AFI57007.1
                    47018 - 50896 (+) QmnA3
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                      • AFI57008.1
                      50899 - 52137 (+) QmnE
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                        • AFI57009.1
                        52134 - 53324 (+) QmnF
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                          • AFI57010.1
                          53328 - 54095 (-) regulator
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                            • AFI57011.1
                            54933 - 56534 (-) PQQ-dependent dehydrogenase
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                              • AFI57012.1
                              56707 - 57837 (+) QmnH
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                                • AFI57013.1
                                57872 - 58918 (-) QmnI
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                                  • AFI57014.1
                                  58923 - 59408 (-) QmnJ
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                                    • AFI57022.1
                                    59506 - 60684 (-) QmnRs1
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                                      • AFI57021.1
                                      60723 - 61406 (-) QmnRs2
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                                        • AFI57020.1
                                        61403 - 62461 (-) QmnK
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                                          • AFI57019.1
                                          62474 - 62932 (-) QmnL
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                                            • AFI57018.1
                                            63075 - 63734 (+) QmnM
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                                              • AFI57017.1
                                              63731 - 64123 (+) QmnN
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                                                • AFI57016.1
                                                64133 - 65482 (-) QmnRg2
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                                                  • AFI57015.1
                                                  65475 - 66143 (-) QmnRg3
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                                                    • AFI57023.1
                                                    66295 - 67326 (+) 3-oxoacyl-ACP synthase III (KS)
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                                                      • AFI57024.1
                                                      67326 - 69167 (+) glyceryltransferase/phosphatase
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                                                        • AFI57025.1
                                                        69173 - 69388 (+) ACP
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                                                          • AFI57026.1
                                                          69385 - 70230 (+) 2-oxoacid dehydrogenase, acyltransferase
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                                                            • AFI57027.1
                                                            70227 - 71438 (+) cytochrome p450
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                                                              • AFI57028.1
                                                              71667 - 74474 (-) QmnRg4
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                                                                • AFI57029.1
                                                                74961 - 77426 (+) regulator
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                                                                  • AFI57030.1
                                                                  77436 - 79640 (-) exodeoxyribonuclease
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                                                                    • AFI57031.1
                                                                    79687 - 80409 (+) precorrin 6a synthase
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                                                                      • AFI57032.1
                                                                      80473 - 81780 (+) dehydrogenase
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                                                                        • AFI57033.1
                                                                        81777 - 82241 (-) regulator
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                                                                          Biosynthesis information
                                                                          Annotation changelog

                                                                          Entry version: 4

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          Update chemical activity to schema version 2.11
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                          Entry version: 3

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          Updated bioactivity data
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                          Entry version: 2

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          Migrated from v1.4
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          Updated compound(s) information (NPAtlas curation)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                          Entry version: 1

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          Submitted
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          Detailed domain annotation
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