LOCUS       BGC0000134             31332 bp    DNA     linear   PLN 12-AUG-2008
DEFINITION  Pochonia chlamydosporia strain ATCC 16683 radicicol gene cluster,
            partial sequence.
ACCESSION   BGC0000134
VERSION     BGC0000134
KEYWORDS    .
SOURCE      Pochonia chlamydosporia (Metacordyceps chlamydosporia)
  ORGANISM  Pochonia chlamydosporia
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Clavicipitaceae;
            Pochonia.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 12:57:13
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..31332
                     /culture_collection="ATCC:16683"
                     /db_xref="taxon:280754"
                     /mol_type="genomic DNA"
                     /organism="Pochonia chlamydosporia"
                     /strain="ATCC 16683"
     protocluster    1..31332
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1391:30251]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1392..30251
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..31332
                     /SMILES="C([*])C(-O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..31332
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000134"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..31332
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<1392..>7664)
                     /gene="Rdc1"
     mRNA            complement(<1392..>7664)
                     /gene="Rdc1"
                     /product="non-reducing polyketide synthase"
     CDS             complement(1392..7664)
                     /NRPS_PKS="Domain: SAT (11-250). E-value: 8.7e-48. Score:
                     154.8. Matches aSDomain: nrpspksdomains_Rdc1_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (377-808). E-value:
                     3.4e-139. Score: 456.2. Matches aSDomain:
                     nrpspksdomains_Rdc1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (913-1209). E-value: 1e-81.
                     Score: 266.5. Matches aSDomain:
                     nrpspksdomains_Rdc1_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1291-1611). E-value: 2e-90. Score:
                     295.2. Matches aSDomain: nrpspksdomains_Rdc1_PT.1"
                     /NRPS_PKS="Domain: ACP (1656-1721). E-value: 1.8e-13.
                     Score: 42.5. Matches aSDomain: nrpspksdomains_Rdc1_ACP.1"
                     /NRPS_PKS="Domain: Thioesterase (1817-1961). E-value:
                     3.1e-17. Score: 55.6. Matches aSDomain:
                     nrpspksdomains_Rdc1_Thioesterase.1"
                     /codon_start=1
                     /gene="Rdc1"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 71.7; E-value:
                     7.9e-22)"
                     /gene_kind="biosynthetic"
                     /product="non-reducing polyketide synthase"
                     /protein_id="ACD39770.1"
                     /sec_met_domain="itr_KS (E-value: 6.4e-144, bitscore:
                     468.2, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.9e-83, bitscore: 266.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-14, bitscore:
                     41.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSHTSAAKVVFLVGDQVDSWHNGLQHVIKAAGATPWLQSYLDDL
                     SNAIKAEIAEAALDNALHASLGTFSSLLELGERYRHRSDDLGMAQCLLLHAVRSSLFLQ
                     MAKQSAHILSPESQTEWLGISGGLISLSPRFVAEDFETLREASIEIGRLFVRLCKLVSV
                     RSRAIEDNTGVWGWAILGVSKDEIRKGLDKFQQNMRIPAIKRAQVGVTGPGWSTIIGPP
                     SVLDLCIKQCPAIATATKNPLNIHALQHTLAITQTDLNYIVGNSQLMSRALHHIRPRLW
                     GMDDPEATYQNWGDMLRAICSQVLSLSLDIPEAVANLGASLRGCDSVQIIQMDNTSHGP
                     FVSTALKAPGRKATLLETHSYLQTQFQGTEPPQKTGRIAIVGMSGRGPRSDNIDEFWDV
                     IMQKQDTCTEVPKDRFDIDEFYCEEHGKGNKICTMTTKYGCFMDKPGHFDARFFHISPR
                     ESMLMDPGHRHFLMSSYEALEMAGYSDGPTKLTDPNRIAAFYGQVTDDWHDQSHPTLGC
                     DAYTLQGVQRAFSSGRLAWQFKWEGPTYSLDSACASTTAAIHLACMSLLSNDIDMAVAG
                     ASNILNYPHSFACLSKSGVLSDTGNCKPYRDDADGYCRADFVGSVVLKRLEDAVADNDN
                     ILAVIASSGRNHSGNSTSITSSDPGAQERLFRKVLRNANVSPDDISYVEMHGTGTPVGD
                     PAEMSAVGNVFKHRRRADGPLPVGAVKANFGHSEGAAGMASLLKCIMMFKTDTIPPQAG
                     MPHALNPNFPPLSELNVEIPAEPKEFKKTRSGEPRRILLNNFDAAGGNACLLLEDWDGS
                     HSPVAQLEDTTDTRSSHVVTLSSRTQAAHKANKQNFLNWLRENTTARLADIAYTTAARR
                     MHHPIRSAYTASTTEELMARVEASIQVSESSSLTSQQTPIIFVFSGQGSHYAGMGSDLY
                     QTSPSFRETVDLCGHIGKIHGFPPFIDLIADKAIDMSTKSTVQTQLAVLTLEIGLAAFW
                     KAAGVQPSAVMGHSLGEYAALHVSGVLSLADVLYLVGQRASLLLERCEENGFAMLAVAM
                     SAKETQELLDSNKEFPSCSIACFNGPNATVISGEAHDISQLQGRVSKASKVLPVPYGFH
                     SFQMDSIISEYSTLADGVTFSEPKIPVASTLVGSMIETKDIINSVYLAQQTRQPVDFIG
                     GLNAIQQMFNDPIWLEIGPNQVCTQFVRASSSSSSPNTKTLSTLEGQSRDWVAINKCMA
                     MLYTQGIAIDWLALHKPFMNSLRMVTLPAYAWDTKDYWITYAEAKAVQGTTSSAPRDIK
                     QPIISTFAQHVAKESSSNAGKLEITFRASVADQNLQAVMEGHRMEQLPICPGSGFCEAA
                     FSAAAYVLESIGRKEDATVTKMRLQHPVMHRPLTKNLVGPDGELFTTITMESKDSNNIH
                     VSWKASASGPKSSMFEMGTCTLVVQKNVKALQATWDRTAYLVRDRMDSIIKSAEDGQGH
                     WLKHDIFYSLFATTVQYDPLYKCTKMAYISNDFSEAVAEVVLQDNPADAKFMASPYWGE
                     GIVHIAGFVVNANPLRSPGTCFINSGFESFEQTVEFRAGKSYLAYARAHQVEEGRKICQ
                     VFVFDSEGKIVAQCYNLSFVRISNALLQHNLSEGASKPVGRGMAKQEKQEVPATTEVVR
                     QPEKEESRHSVDTPSFSDVLINTIVSETGLDPSELTDDTVVAELGVDSIMSIEIANKVS
                     NATGEQLTPMFLHEYPTIGDIKRAFDILTPVSSESDAELTEEYDLLEDTVTEEAVVHVP
                     SPSSTSLEAVVTGSITTKQRDAPQQPRSIGDGPEPAVRFTLLHGRASKRVQDQQASPSP
                     FYLIADGTGSIATYLHLPPHINTKMTIYGVDSPYLHCPSRLTPDVGIPGIAKLIVDELV
                     KRQPQGVPFWLGGFSGGAMIAYEIARQLSALGHVIDSLLLIDMCPPRQIQAQRYDDELG
                     LAMFDAISGNDDSGVWESSDKTHQHLKALFASVSAYNPPPLAKGESPPAKRVALIWAQK
                     GMIDRCANSPRFRQILADRGLVTESYPGFMEDPKLGPVAWSLIHKTESDLGPNGWDKFV
                     GRDELLCMAVEADHLELPTPEFVHLLGEKMDMAFEHFGR"
     misc_feature    1392..>30251
                     /note="radicicol gene cluster"
     aSDomain        complement(1782..2213)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc1_Thioesterase.1"
                     /evalue="3.10E-17"
                     /label="Rdc1_Thioesterase.1"
                     /locus_tag="Rdc1"
                     /protein_end="1961"
                     /protein_start="1817"
                     /score="55.6"
                     /tool="antismash"
                     /translation="LIADGTGSIATYLHLPPHINTKMTIYGVDSPYLHCPSRLTPDVGI
                     PGIAKLIVDELVKRQPQGVPFWLGGFSGGAMIAYEIARQLSALGHVIDSLLLIDMCPPR
                     QIQAQRYDDELGLAMFDAISGNDDSGVWESSDKTHQHLKA"
     aSModule        complement(1782..6533)
                     /complete
                     /domains="nrpspksdomains_Rdc1_PKS_KS.1"
                     /domains="nrpspksdomains_Rdc1_PKS_AT.1"
                     /domains="nrpspksdomains_Rdc1_PT.1"
                     /domains="nrpspksdomains_Rdc1_ACP.1"
                     /domains="nrpspksdomains_Rdc1_Thioesterase.1"
                     /final_module
                     /iterative
                     /locus_tags="Rdc1"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(1959..2036)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc1_0005"
                     /evalue="1.60E-06"
                     /label="NRPS-te1"
                     /locus_tag="Rdc1"
                     /protein_end="1902"
                     /protein_start="1876"
                     /score="20.6"
                     /tool="antismash"
                     /translation="QPQGVPFWLGGFSGGAMIAYEIARQL"
     aSDomain        complement(2502..2696)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc1_ACP.1"
                     /evalue="1.80E-13"
                     /label="Rdc1_ACP.1"
                     /locus_tag="Rdc1"
                     /protein_end="1721"
                     /protein_start="1656"
                     /score="42.5"
                     /tool="antismash"
                     /translation="VLINTIVSETGLDPSELTDDTVVAELGVDSIMSIEIANKVSNATG
                     EQLTPMFLHEYPTIGDIKRA"
     aSDomain        complement(2832..3791)
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc1_PT.1"
                     /evalue="2.00E-90"
                     /label="Rdc1_PT.1"
                     /locus_tag="Rdc1"
                     /protein_end="1611"
                     /protein_start="1291"
                     /score="295.2"
                     /tool="antismash"
                     /translation="AQHVAKESSSNAGKLEITFRASVADQNLQAVMEGHRMEQLPICPG
                     SGFCEAAFSAAAYVLESIGRKEDATVTKMRLQHPVMHRPLTKNLVGPDGELFTTITMES
                     KDSNNIHVSWKASASGPKSSMFEMGTCTLVVQKNVKALQATWDRTAYLVRDRMDSIIKS
                     AEDGQGHWLKHDIFYSLFATTVQYDPLYKCTKMAYISNDFSEAVAEVVLQDNPADAKFM
                     ASPYWGEGIVHIAGFVVNANPLRSPGTCFINSGFESFEQTVEFRAGKSYLAYARAHQVE
                     EGRKICQVFVFDSEGKIVAQCYNLSFVRISNALLQHNLS"
     aSDomain        complement(4038..4925)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc1_PKS_AT.1"
                     /evalue="1.00E-81"
                     /label="Rdc1_PKS_AT.1"
                     /locus_tag="Rdc1"
                     /protein_end="1209"
                     /protein_start="913"
                     /score="266.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGSHYAGMGSDLYQTSPSFRETVDLCGHIGKIHGFPPFIDL
                     IADKAIDMSTKSTVQTQLAVLTLEIGLAAFWKAAGVQPSAVMGHSLGEYAALHVSGVLS
                     LADVLYLVGQRASLLLERCEENGFAMLAVAMSAKETQELLDSNKEFPSCSIACFNGPNA
                     TVISGEAHDISQLQGRVSKASKVLPVPYGFHSFQMDSIISEYSTLADGVTFSEPKIPVA
                     STLVGSMIETKDIINSVYLAQQTRQPVDFIGGLNAIQQMFNDPIWLEIGPNQVCTQFVR
                     ASSSSSSPNTKTLST"
     CDS_motif       complement(4572..4688)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc1_0004"
                     /evalue="4.50E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="Rdc1"
                     /protein_end="1031"
                     /protein_start="992"
                     /score="50.9"
                     /tool="antismash"
                     /translation="GVQPSAVMGHSLGEYAALHVSGVLSLADVLYLVGQRASL"
     CDS_motif       complement(4875..4922)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc1_0003"
                     /evalue="4.10E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="Rdc1"
                     /protein_end="930"
                     /protein_start="914"
                     /score="16.2"
                     /tool="antismash"
                     /translation="FSGQGSHYAGMGSDLY"
     aSDomain        complement(5241..6533)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc1_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.40E-139"
                     /label="Rdc1_PKS_KS.1"
                     /locus_tag="Rdc1"
                     /protein_end="808"
                     /protein_start="377"
                     /score="456.2"
                     /tool="antismash"
                     /translation="IAIVGMSGRGPRSDNIDEFWDVIMQKQDTCTEVPKDRFDIDEFYC
                     EEHGKGNKICTMTTKYGCFMDKPGHFDARFFHISPRESMLMDPGHRHFLMSSYEALEMA
                     GYSDGPTKLTDPNRIAAFYGQVTDDWHDQSHPTLGCDAYTLQGVQRAFSSGRLAWQFKW
                     EGPTYSLDSACASTTAAIHLACMSLLSNDIDMAVAGASNILNYPHSFACLSKSGVLSDT
                     GNCKPYRDDADGYCRADFVGSVVLKRLEDAVADNDNILAVIASSGRNHSGNSTSITSSD
                     PGAQERLFRKVLRNANVSPDDISYVEMHGTGTPVGDPAEMSAVGNVFKHRRRADGPLPV
                     GAVKANFGHSEGAAGMASLLKCIMMFKTDTIPPQAGMPHALNPNFPPLSELNVEIPAEP
                     KEFKKTRSGEPRRILLNNFDAAGGNACLLLED"
     CDS_motif       complement(5574..5621)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc1_0002"
                     /evalue="4.80E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="Rdc1"
                     /protein_end="697"
                     /protein_start="681"
                     /score="12.4"
                     /tool="antismash"
                     /translation="YVEMHGTGTPVGDPAE"
     CDS_motif       complement(6372..6404)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc1_0001"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="Rdc1"
                     /protein_end="431"
                     /protein_start="420"
                     /score="-2.8"
                     /tool="antismash"
                     /translation="YCEEHGKGNKI"
     aSDomain        complement(6915..7631)
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc1_SAT.1"
                     /evalue="8.70E-48"
                     /label="Rdc1_SAT.1"
                     /locus_tag="Rdc1"
                     /protein_end="250"
                     /protein_start="11"
                     /score="154.8"
                     /tool="antismash"
                     /translation="FLVGDQVDSWHNGLQHVIKAAGATPWLQSYLDDLSNAIKAEIAEA
                     ALDNALHASLGTFSSLLELGERYRHRSDDLGMAQCLLLHAVRSSLFLQMAKQSAHILSP
                     ESQTEWLGISGGLISLSPRFVAEDFETLREASIEIGRLFVRLCKLVSVRSRAIEDNTGV
                     WGWAILGVSKDEIRKGLDKFQQNMRIPAIKRAQVGVTGPGWSTIIGPPSVLDLCIKQCP
                     AIATATKNPLNIHALQH"
     gene            <8912..>10848
                     /gene="Rdc2"
     mRNA            join(<8912..9036,9114..9210,9280..9319,9406..9813,
                     9882..10424,10502..>10848)
                     /gene="Rdc2"
                     /product="non-heme halogenase"
     CDS             join(8912..9036,9114..9210,9280..9319,9406..9813,
                     9882..10424,10502..10848)
                     /codon_start=1
                     /gene="Rdc2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 407; E-value: 1.8e-123)"
                     /gene_kind="biosynthetic-additional"
                     /product="non-heme halogenase"
                     /protein_id="ACD39771.1"
                     /sec_met_domain="Trp_halogenase (E-value: 3.8e-17,
                     bitscore: 50.6, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVPKSCTILVAGGGPAGSYAAAALAREGNDVVLLEADQHPRYHI
                     GESMLPSLRPLLRFIDLEDKFDAHGFQKKLGAAFKLTSKREGSHGPRGYSWNVVRSESD
                     EILFNHARESGAQAFQGIKINAIEFEPYEEEYPNGEKVANPGKPTSAKWSSKDGSSGDI
                     AFKYLVDATGRIGIMSTKYLKNRHYNEGLKNLAIWGYYKNNIPWAQGTPRENQPFFEGM
                     RDGAGWCWTIPLHNGTVSVGAVMRKDLFFEKKKSLGENATNTQIMAECMKLCPTIGELL
                     APAELVSDIKQATDYSYSATAYAGPNFRIVGDAGCFIDPFFSSGHHLAVAGALAAAVSI
                     NASIKGDCTEYEASRWHAKKVDEGYTLFLLVVMAALKQIRMQENPVLSDVDEDGFDRAF
                     QFLRPEAVKKFTKEDVAQTIDFAVHALNNMAELDMDIPEHMINGDKEGENGVTNGNNGA
                     AKTAGLASNMEKLTNDEEKVLNGLRILGKAAPGGTLADFEGTAIDGLMPRLEHGKLGLN
                     KV"
     gene            <12358..>14159
                     /gene="Rdc3"
     mRNA            join(<12358..12629,12748..12921,12986..>14159)
                     /gene="Rdc3"
                     /product="major facilitator superfamily transporter"
     CDS             join(12358..12629,12748..12921,12986..14159)
                     /codon_start=1
                     /gene="Rdc3"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 115.3; E-value:
                     3.9e-35)"
                     /gene_kind="transport"
                     /product="major facilitator superfamily transporter"
                     /protein_id="ACD39772.1"
                     /transl_table=11
                     /translation="MAPSQDLGERDQQQPPAPYPADLENGRYGRIPNGHGSTTGTEGSG
                     TLQLNEKDDATLRPNGSHDVKEEGQETSTNVVDWDGPDDPANPQNWTLSKKWLNISVVG
                     LITFNVPLASSMFAPAVPQLLQDFHTDNASLSTFVVSVYILGLAAGPLILAPMSELYGR
                     LNVYHVGNVLFIIFTVACGLATNINMLVAFRFLAGLVGAAPIAIGAGTIADVTNLQQRG
                     TAMSIWSLGPLLGPSIGPVIGGFLAQAAGWRWIFWLLAIIAGAVAIISFFVLQETHAPT
                     LLKRKTNRLRKETGNMALRSKLDTQLPPKEMFLRAIVRPCKMLLFSPVCLILSFYSAFV
                     YALIYFMFSTFSFIFKASYGFNQGTVGLVYLACGIGMLLGLGIQQLTGDRIRQRLADKR
                     NGGDHKPEYRFPPMFMAGGLLPAGLFMYGWAVQHHVQWAVPLLGTLIAGIGICIISICI
                     NTYLVDTFTMYAASALAASAVLRSVFAAVLPLFALQMYNKLGLGWGNSLLAFVGLGMWP
                     ITFLFFVHGEKLRKNPKFQIKF"
     gene            complement(<19331..>20929)
                     /gene="Rdc4"
     mRNA            complement(join(<19331..19493,19551..19749,19813..>20929))
                     /gene="Rdc4"
                     /product="cytochrome P450"
     CDS             complement(join(19331..19493,19551..19749,19813..20929))
                     /codon_start=1
                     /gene="Rdc4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 366.9; E-value:
                     2.7e-111)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450"
                     /protein_id="ACD39773.1"
                     /sec_met_domain="p450 (E-value: 4.4e-66, bitscore: 211.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVSPQLLGYVVYTAIYNVYFHPLANFPGPKYLAASRIPLAFKRL
                     TGEEVAMTYKLHIKYGPYVRVSPDELSTISTAATKDVYGHNTRAGGVPKDFKAYYMKNQ
                     RKDGTEGLLTAGDEEHYRQRKVFAPAFSDRAIREQEPLLKKYTDLLVAKSYEKCQTAGK
                     VDMVMFFNFATFDFIADCVFGDSLHHLESMEYHPFLANITATVRFSAMRRVLRSFPILQ
                     AIFEAFMPKSMIKKRLEHVKFCDERVMNRLANDNPSHPDFWTLVEHAEAKGNGLTKGEM
                     RQNGFLLLTAATETTSSLMSAITYLLCKNPEKMKKLQAEVRGAFKSTDEMNTITLPKLQ
                     YLQMAIEEGLRVYPPVPGGLPRRVVQPGTTLDGSASNMHIQSVVFYSQYASYHSPSHFA
                     RPHEFIPERWSQNPPAEFANDRLEAVQAFSAGPRDCIGKNLAYHEARMLLAKFVFTYDI
                     ELCKESSDWIKQKVYIVGAKSPLWVKLVKHERAD"
     gene            <23042..>30251
                     /gene="Rdc5"
     mRNA            join(<23042..26947,27006..>30251)
                     /gene="Rdc5"
                     /product="reducing polyketide synthase"
     CDS             join(23042..26947,27006..30251)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (12-438). E-value:
                     2.3e-167. Score: 549.0. Matches aSDomain:
                     nrpspksdomains_Rdc5_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (550-862). E-value: 1.1e-100.
                     Score: 328.7. Matches aSDomain:
                     nrpspksdomains_Rdc5_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (931-1120). E-value: 5.2e-26.
                     Score: 83.8. Matches aSDomain:
                     nrpspksdomains_Rdc5_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1662-1977). E-value: 6.9e-117.
                     Score: 381.9. Matches aSDomain:
                     nrpspksdomains_Rdc5_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2001-2181). E-value: 8.1e-53.
                     Score: 170.9. Matches aSDomain:
                     nrpspksdomains_Rdc5_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2294-2370). E-value: 1.6e-12.
                     Score: 39.5. Matches aSDomain:
                     nrpspksdomains_Rdc5_PKS_PP.1"
                     /codon_start=1
                     /gene="Rdc5"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 79.1; E-value:
                     4.5e-24)"
                     /gene_kind="biosynthetic"
                     /product="reducing polyketide synthase"
                     /protein_id="ACD39774.1"
                     /sec_met_domain="PKS_KS (E-value: 2.1e-168, bitscore:
                     549.0, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1e-101, bitscore: 328.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.5e-18, bitscore:
                     54.8, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.8e-48, bitscore:
                     153.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.5e-09, bitscore:
                     25.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSATAQDARAPIAIIGMSCRFPGDAEDPLKFWDLLKEGREAYSE
                     KTHRYNEEAFYHPGGQFNNKRQNVLPVKGGYMLKQDPYVFDAAFFNITAAEAISFDPKQ
                     RIAMEVTYEAFENAGMTLQKAAGTRTACYIGTSMSDYRDSIVRDFGNYPKYHLLGTSDE
                     MISNRISHFFDLRGPSATIETACSSSHVATHIACQSIQSGESDMAVVGGIGMLLVPEST
                     MQLNNLGFLSAFGQSRAFDASGAGYGRGEGCGIFILKRLDKAMEDGDTIRAIIRGSGVN
                     SDGWTQGVTMPSGDAQASLIEYVYKSNGLDYEGTQYVEAHGTGTKVGDPTEAEALHRTI
                     GQPTPKRKKLWMGSVKTNIGHLEAAAGAASMVKGVLAMEHGFIPPTLHFKNPNPAIKFD
                     EWQLGVPTKLMPWPACQTRRMSTSAFGMGGTNAHLVLERPNEPAIPILERGAIGVSRKN
                     QKRLFVFSSHDQAGFKRICDRLVEHVDTLGPKSSNPDYLANLAHTLAVGRSGLTWKSSC
                     FAENIVELREHLTSSSLPEGAVRAAGGQTRIGFVFTGQGAQWARMGVELMDRKVFGKSV
                     AKSTALLQEMGCEWDPVVELSKSQKESQLVKPEISQPICTILQIALIDELRSWGIRPAK
                     VVGHSSGEIAAAYCMGALTHRDALAAAYFRGKASANVKRRGGMMAVGTTPEDAKKLITE
                     TKAQATVACVNSPRSITLSGDVDALEALRETFEKQGVFARRLKVDVAYHSSHMRSCSAE
                     YQSSIMDLEPSELDGANESKEPILMVSSVTGGLVDAEALGPYYWIRNLISPVLFSDALK
                     ELVCPADSGGSSDVDMLIEIGPHSALRAPIEQILSHHDIKNVEYASMLTRGESGSETIL
                     GFAAELFRRGVPFDIAKANDDAQCRLLTDLPPYPFNHSQQFRAESRLQRETLTQQNPTK
                     SLIGAERPSLDEHERVWRGFINLDDEPWLRDHTVGSTVLFPGAAVITIVLEAAQQMAEA
                     GKTIRSLTLRDISFMAMMTLLEGTPTEVITHVRPHLVATTGTTPATWWEFTVSSCTGVT
                     SNVRNNCRGLFSINYEDSRSSHMEMELERFEGDRVATYHQIKKECVEVISKQAFYDTLA
                     RSALAYGPHFQGVDNCRPGNGQTAFEVIVSDLGETFNKDKLTRPFLIHGGTLDSIFQAW
                     VGSTKDSNGPGSFGFEKPLLPKSIGELEISLDFPGEVGYSLNGLSTSKKHGFSEWSTDI
                     TMFDRNVSKLLLSVKDFHLAELEVEDADRPDRTEHVDVDPAEISSEPKWNYALDFMSTQ
                     EIKQVVETASSSDDKLMQFISLAIHQRPNLEILELVESANQLRQTAVSKLPRGRLLPNQ
                     ASCAILGGDYDNNNESAAAFGRIFGLDSSEAVPSDVAPADLVIANFNISNLEDIAERLV
                     VLAKPEARILLIADKKVDSSVTSLADKGFDLVFSTEADSESLSLYCFGKKEEPQPERLT
                     NGSTGQEVVILEPSSLSAESDRFSKDLQHALDNIGYNVSTVTDIHGAHAAKARIYVSLL
                     EIEQPVLENLSQSEFEGLRDLLLNCDRLLWITRGDGPSLQLVDGFSRTIRSEFAGVEFQ
                     VLHLSGKNSRQGPSLAAQIVFKQSTESEFREDDGHLQISRWYRSVEEDDHIRNHLLDSI
                     RTVSLPVGGNIEDNSSYRLAVGKPGLLNTLHFVSDDNTEAPLADNEVEMQVKASGINFR
                     DIMGSMGLLPVSGIGQEASGIVVRVGKLGASSLKPGDRISTLTVGGTHATRIRCDYRVA
                     KKIPEGMSFEEAAGIPVVHCTAYYALVKLAKLRPGQSVLIHAAAGGTGQAALQLAKHLG
                     LTIFATVGTDTKRALIREKYGVPDENIFHSRDGSFVKGIERATNGRGVDCVLNSLSGEL
                     LRLSWGCLATFGTFVEIGLRDITDNMRLDMRPFAKSTTFSFINMVTLLQENPDAMGEIL
                     ESVFEMIHQNVLQPVFPVTVYPVGKVEEAFRLMQQGKHVGKMILSFAAGDARAPVLCRA
                     KDSFKLDPNATYLFIGGLGGLGRSMAVGFVACGARNIAFLSRSGDSKPEAKAVVDELRE
                     LGTRVQVYLGDVSDEASFRGAMEQCSRELPPVKGVIQMAMVLRDVVFEKMKYDDWTTGL
                     RPKVQGTWNLHTFFDKDRPLDFMIFFSSIAGVFGNPSQAQYAAGNTYQDSLAKYRRDRG
                     LKAVSVNLGIMRDVGVIAEGDSHFMQQWEEVLGIREPAFHALIKSIINGQLETSNIREA
                     AKCPVQVTVGLGTGDILARNKIREPDYFRDPRFGALAVCSSTSTAAASSGENGVSIASQ
                     LAGLSNEADPEEAAGPIITKALVSKLAKILQVPPSEIDSSRPMYRYGVDSLVAIEVRNW
                     ITKEMSANMSLMDILGAMPMEQFAVQIAKKSKLVGGS"
     aSDomain        23078..24355
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc5_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.30E-167"
                     /label="Rdc5_PKS_KS.1"
                     /locus_tag="Rdc5"
                     /protein_end="438"
                     /protein_start="12"
                     /score="549.0"
                     /tool="antismash"
                     /translation="IAIIGMSCRFPGDAEDPLKFWDLLKEGREAYSEKTHRYNEEAFYH
                     PGGQFNNKRQNVLPVKGGYMLKQDPYVFDAAFFNITAAEAISFDPKQRIAMEVTYEAFE
                     NAGMTLQKAAGTRTACYIGTSMSDYRDSIVRDFGNYPKYHLLGTSDEMISNRISHFFDL
                     RGPSATIETACSSSHVATHIACQSIQSGESDMAVVGGIGMLLVPESTMQLNNLGFLSAF
                     GQSRAFDASGAGYGRGEGCGIFILKRLDKAMEDGDTIRAIIRGSGVNSDGWTQGVTMPS
                     GDAQASLIEYVYKSNGLDYEGTQYVEAHGTGTKVGDPTEAEALHRTIGQPTPKRKKLWM
                     GSVKTNIGHLEAAAGAASMVKGVLAMEHGFIPPTLHFKNPNPAIKFDEWQLGVPTKLMP
                     WPACQTRRMSTSAFGMGGTNAHLVLER"
     aSModule        23078..30209
                     /complete
                     /domains="nrpspksdomains_Rdc5_PKS_KS.1"
                     /domains="nrpspksdomains_Rdc5_PKS_AT.1"
                     /domains="nrpspksdomains_Rdc5_PKS_DH.1"
                     /domains="nrpspksdomains_Rdc5_PKS_ER.1"
                     /domains="nrpspksdomains_Rdc5_PKS_KR.1"
                     /domains="nrpspksdomains_Rdc5_PKS_PP.1"
                     /iterative
                     /locus_tags="Rdc5"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       23570..23617
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0001"
                     /evalue="5.90E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="Rdc5"
                     /protein_end="192"
                     /protein_start="176"
                     /score="15.4"
                     /tool="antismash"
                     /translation="GPSATIETACSSSHVA"
     CDS_motif       23759..23797
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0002"
                     /evalue="4.20E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="Rdc5"
                     /protein_end="252"
                     /protein_start="239"
                     /score="7.5"
                     /tool="antismash"
                     /translation="FDASGAGYGRGEG"
     CDS_motif       23990..24037
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0003"
                     /evalue="1.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="Rdc5"
                     /protein_end="332"
                     /protein_start="316"
                     /score="13.8"
                     /tool="antismash"
                     /translation="YVEAHGTGTKVGDPTE"
     CDS_motif       24098..24142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0004"
                     /evalue="4.40E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="Rdc5"
                     /protein_end="367"
                     /protein_start="352"
                     /score="12.6"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAAAG"
     CDS_motif       24689..24742
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0005"
                     /evalue="4.80E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="Rdc5"
                     /protein_end="567"
                     /protein_start="549"
                     /score="18.9"
                     /tool="antismash"
                     /translation="FVFTGQGAQWARMGVELM"
     aSDomain        24692..25627
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc5_PKS_AT.1"
                     /evalue="1.10E-100"
                     /label="Rdc5_PKS_AT.1"
                     /locus_tag="Rdc5"
                     /protein_end="862"
                     /protein_start="550"
                     /score="328.7"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWARMGVELMDRKVFGKSVAKSTALLQEMGCEWDPVVE
                     LSKSQKESQLVKPEISQPICTILQIALIDELRSWGIRPAKVVGHSSGEIAAAYCMGALT
                     HRDALAAAYFRGKASANVKRRGGMMAVGTTPEDAKKLITETKAQATVACVNSPRSITLS
                     GDVDALEALRETFEKQGVFARRLKVDVAYHSSHMRSCSAEYQSSIMDLEPSELDGANES
                     KEPILMVSSVTGGLVDAEALGPYYWIRNLISPVLFSDALKELVCPADSGGSSDVDMLIE
                     IGPHSALRAPIEQILSHHDIKNVEYASMLTR"
     CDS_motif       24929..25021
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0006"
                     /evalue="7.80E-10"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="Rdc5"
                     /protein_end="660"
                     /protein_start="629"
                     /score="31.2"
                     /tool="antismash"
                     /translation="GIRPAKVVGHSSGEIAAAYCMGALTHRDALA"
     aSDomain        25835..26401
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc5_PKS_DH.1"
                     /evalue="5.20E-26"
                     /label="Rdc5_PKS_DH.1"
                     /locus_tag="Rdc5"
                     /protein_end="1120"
                     /protein_start="931"
                     /score="83.8"
                     /tool="antismash"
                     /translation="LIGAERPSLDEHERVWRGFINLDDEPWLRDHTVGSTVLFPGAAVI
                     TIVLEAAQQMAEAGKTIRSLTLRDISFMAMMTLLEGTPTEVITHVRPHLVATTGTTPAT
                     WWEFTVSSCTGVTSNVRNNCRGLFSINYEDSRSSHMEMELERFEGDRVATYHQIKKECV
                     EVISKQAFYDTLARSALAYGPHFQGV"
     CDS_motif       25913..25990
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0007"
                     /evalue="2.50E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="Rdc5"
                     /protein_end="983"
                     /protein_start="957"
                     /score="32.8"
                     /tool="antismash"
                     /translation="WLRDHTVGSTVLFPGAAVITIVLEAA"
     CDS_motif       27384..27407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0008"
                     /evalue="1.50E+01"
                     /label="PKSI-ER_m7"
                     /locus_tag="Rdc5"
                     /protein_end="1436"
                     /protein_start="1428"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="KGFDLVFS"
     aSDomain        28086..29030
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc5_PKS_ER.1"
                     /evalue="6.90E-117"
                     /label="Rdc5_PKS_ER.1"
                     /locus_tag="Rdc5"
                     /protein_end="1977"
                     /protein_start="1662"
                     /score="381.9"
                     /tool="antismash"
                     /translation="GLLNTLHFVSDDNTEAPLADNEVEMQVKASGINFRDIMGSMGLLP
                     VSGIGQEASGIVVRVGKLGASSLKPGDRISTLTVGGTHATRIRCDYRVAKKIPEGMSFE
                     EAAGIPVVHCTAYYALVKLAKLRPGQSVLIHAAAGGTGQAALQLAKHLGLTIFATVGTD
                     TKRALIREKYGVPDENIFHSRDGSFVKGIERATNGRGVDCVLNSLSGELLRLSWGCLAT
                     FGTFVEIGLRDITDNMRLDMRPFAKSTTFSFINMVTLLQENPDAMGEILESVFEMIHQN
                     VLQPVFPVTVYPVGKVEEAFRLMQQGKHVGKMIL"
     CDS_motif       28176..28211
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0009"
                     /evalue="3.30E-03"
                     /label="PKSI-ER_m1"
                     /locus_tag="Rdc5"
                     /protein_end="1704"
                     /protein_start="1692"
                     /score="10.6"
                     /tool="antismash"
                     /translation="GINFRDIMGSMG"
     CDS_motif       28230..28268
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0010"
                     /evalue="1.60E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="Rdc5"
                     /protein_end="1723"
                     /protein_start="1710"
                     /score="11.4"
                     /tool="antismash"
                     /translation="IGQEASGIVVRVG"
     CDS_motif       28401..28445
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0011"
                     /evalue="4.00E-05"
                     /label="PKSI-ER_m4"
                     /locus_tag="Rdc5"
                     /protein_end="1782"
                     /protein_start="1767"
                     /score="16.9"
                     /tool="antismash"
                     /translation="AAGIPVVHCTAYYAL"
     CDS_motif       28470..28532
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0012"
                     /evalue="2.80E-09"
                     /label="PKSI-ER_m5"
                     /locus_tag="Rdc5"
                     /protein_end="1811"
                     /protein_start="1790"
                     /score="29.3"
                     /tool="antismash"
                     /translation="GQSVLIHAAAGGTGQAALQLA"
     CDS_motif       28542..28589
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0013"
                     /evalue="1.50E-04"
                     /label="PKSI-ER_m6"
                     /locus_tag="Rdc5"
                     /protein_end="1830"
                     /protein_start="1814"
                     /score="14.6"
                     /tool="antismash"
                     /translation="GLTIFATVGTDTKRAL"
     CDS_motif       28671..28709
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0014"
                     /evalue="1.10E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="Rdc5"
                     /protein_end="1870"
                     /protein_start="1857"
                     /score="14.7"
                     /tool="antismash"
                     /translation="TNGRGVDCVLNSL"
     CDS_motif       28983..29030
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0015"
                     /evalue="3.50E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="Rdc5"
                     /protein_end="1977"
                     /protein_start="1961"
                     /score="19.8"
                     /tool="antismash"
                     /translation="AFRLMQQGKHVGKMIL"
     aSDomain        29103..29642
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc5_PKS_KR.1"
                     /evalue="8.10E-53"
                     /label="Rdc5_PKS_KR.1"
                     /locus_tag="Rdc5"
                     /protein_end="2181"
                     /protein_start="2001"
                     /score="170.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="ATYLFIGGLGGLGRSMAVGFVACGARNIAFLSRSGDSKPEAKAVV
                     DELRELGTRVQVYLGDVSDEASFRGAMEQCSRELPPVKGVIQMAMVLRDVVFEKMKYDD
                     WTTGLRPKVQGTWNLHTFFDKDRPLDFMIFFSSIAGVFGNPSQAQYAAGNTYQDSLAKY
                     RRDRGLKAVSVNLGIMR"
     CDS_motif       29106..29204
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0016"
                     /evalue="2.00E-12"
                     /label="PKSI-KR_m1"
                     /locus_tag="Rdc5"
                     /protein_end="2035"
                     /protein_start="2002"
                     /score="39.6"
                     /tool="antismash"
                     /translation="TYLFIGGLGGLGRSMAVGFVACGARNIAFLSRS"
     CDS_motif       29433..29462
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0017"
                     /evalue="5.50E-04"
                     /label="PKSI-KR_m3"
                     /locus_tag="Rdc5"
                     /protein_end="2121"
                     /protein_start="2111"
                     /score="13.2"
                     /tool="antismash"
                     /translation="PKVQGTWNLH"
     CDS_motif       29487..29597
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Rdc5_0018"
                     /evalue="1.10E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="Rdc5"
                     /protein_end="2166"
                     /protein_start="2129"
                     /score="66.2"
                     /tool="antismash"
                     /translation="LDFMIFFSSIAGVFGNPSQAQYAAGNTYQDSLAKYRR"
     aSDomain        29982..30209
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Rdc5_PKS_PP.1"
                     /evalue="1.60E-12"
                     /label="Rdc5_PKS_PP.1"
                     /locus_tag="Rdc5"
                     /protein_end="2370"
                     /protein_start="2294"
                     /score="39.5"
                     /tool="antismash"
                     /translation="ADPEEAAGPIITKALVSKLAKILQVPPSEIDSSRPMYRYGVDSLV
                     AIEVRNWITKEMSANMSLMDILGAMPMEQFA"
ORIGIN
        1 gaattcgtgg tcattgcgtt gcttgggagg agagagagag atggggcatt gccttcatat
       61 gtaactgcga gatactggtc tctgggaaat ttctcatcca gtccagttac tggaccgtgg
      121 tagaggaact catcgagggt ctcattgtca atacgcccca aggtgagttc cccggctcga
      181 atttgcagca cacgttgctc acagctggac catttataca cagcttctac caaagaccct
      241 gatgcagcaa gaaaaagaat gttgtttgag acgtgtctgg atctcatgat gacaaagaca
      301 gctttcagaa cgagccaaga agattgattt ggtggagcgt tgatgctcac tccatactcc
      361 tgtaatttgt gctcataggt ttggcaggta tatgtatgtt ctaaacaaga tttcaaagtg
      421 aggcaaggta cgttttattg agaagcagta cacaacaagg ctaccaatag aaaggccagg
      481 cagaccgttc aattcgaaat attttcgtgt gttagcgcca catggcgtta atagcagatc
      541 tccttcagac tgaccggata ttgcgtggcg ctctcagctg gaacgatggt gaggaaaaaa
      601 aatgcaatct tccgcagagt gaacacgggc aatatttgat caacctgcaa aaccctggga
      661 tgctggagcc gtgaactttt aggattgaag tgcaacccta ctgtagctcg gtcatctaaa
      721 taaacacttg actactaggt tgggtaggta cctcagcccg gtgggcgcat actcagaaca
      781 aagctatttt ttgcgtgtgc accagcatgg cgtcgatggc gttctcagaa atttattcga
      841 ggacagcagt gctcgtaagc ctgccacaga tttcagagtg aagctggtga agaagcaaat
      901 caactccgat ctccaaagac aactgttctt cctggctcgt attttaatac tctgcctagt
      961 tgtttgagaa tattttatag cagagatgcg ttggcccgtc tcatggacat ggcgcgcgtt
     1021 gccaccagac tgcttcatgg ttgcgaaaac ttgcacatgg atgtcagctg gcactctggg
     1081 caagagcggg gcgcgggccg agccgccacc taaaacatga aggcaaaact ggggacgtgg
     1141 aaacaaattc gtatgtaagg attcaaagtt taatgttgac catccgttcc ttgttttgac
     1201 accaggaaac ctcagtccct cgtgcgaaag acaataccca aataaagcag cgcgtaaaca
     1261 aatctatgca tcctcctcca cgaccattta gatgcaagtg caaaaatacc acagaggcac
     1321 tacgtttgcg aagctgtccc agctcggtac acaaatatac agcccacatc acatcgtccc
     1381 ccttcacaat ctcatcgtcc aaagtgctca aacgccatgt ccatcttctc accaagcaaa
     1441 tgcacaaact caggcgtagg caactccaaa tgatccgcct caactgccat acacaacaac
     1501 tcatcgcgtc ccacaaactt gtcccagccg ttgggaccaa gatctgactc agtcttgtgt
     1561 ataaggctcc atgcgacggg gcctaacttg ggatcctcca tgaacccagg ataagactct
     1621 gttacaagtc cacggtccgc cagaatctgt ctaaaccgag gactgttggc acagcggtca
     1681 atcatgccct tttgcgccca gatgagagcc acgcgtttcg ccggcggact ctcccccttt
     1741 gccaagggag gtggattata ggcggaaacg gaagcaaata gcgccttcaa atgttggtgt
     1801 gtcttgtcgg aagactccca tacaccgcta tcgtcgttac cagagatggc gtcaaacatg
     1861 gctaaaccga gctcgtcgtc gtacctttgt gcctgtattt gacgcggcgg acacatgtcg
     1921 atgagcagga ggctgtcaat aacatgcccg agagcggata gctggcgcgc aatttcgtag
     1981 gcaatcatgg cgcctcctga aaaccctcct agccagaatg gaactccttg tggttgcctt
     2041 ttgaccagtt cgtctacaat gagcttcgcg atgccgggga taccaacatc tggtgtcagc
     2101 ctgctcgggc agtgaaggta cggtgagtcg acgccgtaaa tggtcatctt ggtattgatg
     2161 tgaggaggga ggtgaagata cgtggctatt gagcctgtgc catccgcaat caaataaaat
     2221 ggcgatgggg atgcttgctg gtcctggaca cgcttggacg cacgaccatg taacagcgta
     2281 aacctgacgg cgggttcagg gccatcccca atagacctgg gttgctgagg tgcatctctc
     2341 tgcttggtcg taatcgagcc tgtgacgacc gcttcaaggg aagttgaact tggtgacggc
     2401 acatgtacaa cagcttcttc cgtcacggtg tcttcaagaa ggtcatactc ctccgtcaac
     2461 tcggcatcag actcagaaga gaccggcgtc aggatgtcaa atgcgcgttt tatatcacca
     2521 attgtagggt actcatgcag aaacatgggc gtcaactgct caccagtcgc gttagatacc
     2581 ttgttggcga tctcaataga catgatggaa tcaacaccca gctcagcgac aaccgtgtca
     2641 tcagtcaact cagacggatc aagacccgtt tccgacacaa tcgtgttgat caaaacgtca
     2701 gaaaaactcg gcgtgtcgac agagtgtctc gattcctcct tttcgggctg ccttacgact
     2761 tcggtggtcg caggcacttc ctgtttctcc tgcttggcca tgccgcgtcc tacaggcttt
     2821 gatgctccct ctgagagatt atgctgcagt agggcgttgc tgattctgac aaaactcaga
     2881 ttgtaacact gggctacaat ctttccctcc gagtcgaaca caaatacttg acagatcttt
     2941 cttccctctt ctacctgatg ggcacgagcg tatgcaaggt acgactttcc ggctctgaac
     3001 tccacggttt gctcaaagct ttcaaaccca gagtttatga aacatgtgcc agggctcctc
     3061 aaggggtttg cgttgaccac aaagcctgca atgtgaacga tgccctcacc ccagtatgga
     3121 gaggccatga acttggcatc ggctggatta tcctgaagaa caacttccgc aacggcctcg
     3181 gaaaagtcat tcgaaatgta tgccatcttg gtgcatttgt agagcgggtc atattggacg
     3241 gtcgttgcaa acagagaata gaaaatgtcg tgcttgagcc agtgaccctg accatcctcg
     3301 gcggacttta taatactgtc catcctgtct ctgactaggt acgcagttct gtcccaagtg
     3361 gcttggagag ctttgacgtt cttttgaact actagagtac aagtgcccat ctcgaacatt
     3421 gaagattttg gcccagaagc agaagctttc catgagacgt ggatgttgtt gctgtctttg
     3481 ctctccatgg tgattgtcgt gaagagctcc ccatcgggcc cgacaagatt cttggtcagt
     3541 gggcgatgca tcactggatg ttgaagcctc atttttgtca cagtcgcatc ttcttttcta
     3601 ccaatggact ctaggacata agcagccgcc gagaaggcgg cttcgcaaaa gccactgcct
     3661 ggacagattg gtagctgttc catccggtgt ccttccatga cagcttgtag attctggtcg
     3721 gcaactgaag ctcggaacgt tatctccagt ttccccgcat tagaagaaga ctctttagca
     3781 acatgctgcg caaatgttga aataatgggt tgtttgatgt ccctgggagc tgacgatgta
     3841 gtaccctgaa cagccttggc ttctgcataa gtaatccaat agtccttcgt atcccatgcg
     3901 tatgccggca gcgtgaccat gcgtaaggaa ttcatgaaag gtttgtgaag agcgagccag
     3961 tcaatggcaa tgccctgcgt atacagcatt gccatacact tattgattgc cacccagtcg
     4021 cgactttgtc cctcgagggt cgacaaggtc ttcgtgttgg gagacgacga acttgaagat
     4081 gctcgcacga actgcgtaca cacctggtta ggtcctattt cgagccagat gggatcattg
     4141 aacatctgct ggatggcatt caagccgcca ataaagtcga ccggctgccg agtctgttgc
     4201 gccaaatata cgctgttgat gatgtctttc gtttcaatca tagaccctac caacgtggag
     4261 gcaactggaa tcttgggttc agaaaaggtc acaccatctg caagagtgct gtattcagaa
     4321 atgatggagt ccatttggaa cgagtgaaag ccatacggca cgggaaggac tttcgaagcc
     4381 ttcgacaccc gaccttgtag ctggctaatg tcgtgagcct cgccactgat aaccgtagca
     4441 tttggaccgt tgaagcacgc tatgctgcat gacgggaact ccttattcga atccagaagc
     4501 tcctgtgtct cctttgcaga catggcaaca gccagcatgg cgaatccatt ttcctcgcac
     4561 ctttctagga gcagagaagc ccgctggcca acaagataca gcacatccgc gagagacagc
     4621 actcccgaaa cgtgaagcgc agcgtactca ccgagagaat ggcccatgac cgcagaaggc
     4681 tgcacaccag ccgctttcca gaatgcagca aggccaatct ccagcgtcaa cactgccagc
     4741 tgcgtctgta cggtggactt ggtcgacata tcaatggcct tgtccgcaat cagatcaatg
     4801 aagggtggaa agccatgaat cttgcctata tgcccgcaga gatcgacggt ctcacgaaac
     4861 gaagggctag tctgatacag atcgcttccc atgccagcgt aatgtgaccc ttgaccagag
     4921 aaaacaaaaa tgatgggagt ctgctgtgat gtgagtgatg acgactctga aacttgaatc
     4981 gaagcctcta ctctggccat gagttcttcc gtcgtgcttg cagtgtatgc cgacctgatg
     5041 gggtggtgca tccttctggc ggccgtagtg tacgcgatat cggcaagtcg agcagttgta
     5101 ttttcccgaa gccaattcaa aaagttctgc ttattggctt tatgcgcggc ttgcgtccga
     5161 gacgacagag ttacaacatg actagaacga gtgtcggttg tgtcttccaa ctgggccacc
     5221 ggcgagtgac tcccatccca atcttcaaga agcaagcagg cattcccacc agctgcatca
     5281 aaattattga gaagaatgcg tcttggttca ccggacctag tcttcttaaa ctcctttggt
     5341 tccgccggta tttcaacatt cagctccgac aacggcggga agttggggtt gagggcgtga
     5401 ggcatgcccg cctgaggtgg tatcgtgtcc gtcttgaaca tcatgatgca cttgaggaga
     5461 gaagccattc cagcagcccc ttcactgtgg ccgaaatttg ctttcactgc cccgacagga
     5521 agagggccat ctgctcgtcg tctgtgtttg aagacgttgc ccacggcact catctcagca
     5581 ggatccccga caggtgttcc tgttccatgc atttctacgt aagagatatc gtccggggag
     5641 acgtttgcgt ttcgcaggac cttgcgaaac agtctctcct gggcaccagg atcggaggac
     5701 gtgatggatg tagagtttcc agaatgattc cttccggacg atgctattac ggcaaggatg
     5761 ttatcattgt ccgccactgc gtcttcaagg cgcttgagta caaccgagcc cacaaagtca
     5821 gcacggcagt atccgtcggc atcatctcgg tagggtttac agtttccagt gtctgacaat
     5881 acgccagact tgctgagaca ggcaaaggag tgagggtagt tgaggatgtt gctagctccc
     5941 gcgacggcca tgtcgatatc gttggacagt aagctcatgc aggctaaatg tatcgctgcc
     6001 gtagtagatg cacacgcaga atctagtgaa tacgtaggac cctcccattt gaactgccat
     6061 gcaagccgtc cagaactaaa cgcgcgttga actccttgaa gggtgtaggc atcgcagccc
     6121 agggttggat gactttgatc gtgccagtcg tcggtaactt ggccgtagaa cgcggcgatt
     6181 ctatttggat ccgtcaattt tgtcggtccg tctgaatacc ctgccatttc caatgcttca
     6241 tagctgctca tcaggaagtg tcgatgcccg ggatccatga gcatggactc ccggggcgag
     6301 atgtggaaga atcgagcatc aaagtggccc ggcttgtcca taaaacagcc atactttgta
     6361 gtcatggtgc agattttgtt gcctttcccg tgctcctcgc agtagaactc gtctatatcg
     6421 aagcggtctt tggggacttc agtgcaggta tcttgcttct gcatgatcac gtcccaaaac
     6481 tcgtcaatgt tgtcactcct tggaccgcgc cccgacatgc caacaatggc tatccgacca
     6541 gtcttttgcg gtggctctgt cccttggaat tgtgtctgga ggtacgagtg tgtctccaga
     6601 agagtggcct tgcgccccgg agctttcagt gcagttgata cgaacggacc gtgactcgta
     6661 ttgtccatct ggataatctg gactgaatca caacccctca gcgaagcacc aagatttgcc
     6721 acagcctctg gaatgtctag tgaaagggaa agcacctgtg agcagatggc tcgcagcatg
     6781 tctccccaat tttgatatgt ggcttcagga tcgtccattc cccaaaggcg gggacgtatg
     6841 tgatgaaggg cccgactcat tagctgagag ttaccgacaa tgtagttgag atctgtttgt
     6901 gttatcgcca atgtgtgttg taaagcgtgg atattcaagg gattctttgt ggcggttgca
     6961 atggcagggc attgcttgat gcagaggtct agaacagacg gtggtccgat gattgtgctc
     7021 catcctggtc cagtaactcc aacttgagct cgttttattg ccggaatcct catattttgc
     7081 tgaaatttat cgagtccctt gcggatctca tcttttgaga cgcctaagat ggcccaaccc
     7141 cagacgccag tgttgtcctc gattgcccta gatcgaactg acaccaactt gcacagtctc
     7201 acaaacagac gaccgatttc tattgaagcc tcccgcaacg tctcaaaatc ttccgcgaca
     7261 aatcggggtg acaagctaat gaggccacca gaaatcccca gccattctgt ttgcgactcc
     7321 ggactcaaga tatgcgctga ctgcttggcc atctgtagga aaagagagga tcggactgcg
     7381 tgtaagagga ggcattgtgc catgcccagg tcatctgagc gatggcggta tctctcgcct
     7441 agctcgagaa ggctcgagaa ggtacccaga ctggcatgta atgcgttgtc aagtgcagcc
     7501 tctgctattt ctgccttaat cgcattgctc aagtcgtcca aatatgattg tagccacgga
     7561 gttgcgccgg ccgctttgat gacgtgttgg aggccattgt gccaggagtc aacttggtct
     7621 ccgacgagaa agacgacttt tgcagccgaa gtatgcgact tcattgggtt ccctggattc
     7681 tttgaagttg gtgggatgag ttcaaacacg ggttgactga caggcaaagt caactttagt
     7741 aagataatgg acggattata ggaatctggt attgatgtgc caatgacaag acgtgggctg
     7801 tcttgaatca ataggataga atgtggaaag cttatagtcc cttagatgta acctgaaccc
     7861 caaggtgact gacagaaagc atcatagaaa atagccggca gtcctcagca tgttttcttc
     7921 gcgtattaat tgaaccgtag caaactcact acttcggctt cataatgtca ttttatcagg
     7981 ccaaggcccc gtcaaatctt ctcactgcca caatgaaggg ttcgctcgcc gcgagcttgc
     8041 cgcaaggcgt ttctgcccta gcaggtacgt aagatgttga cgactctctt tcgtgacact
     8101 tcaaggtgac aagtctacgt tagggcgtga gcatacgaag ctgcacaccc attagatgct
     8161 gttgctgatc cgagtgcatt cctattggcc agtatccatg acaacctgtc atgtaagccg
     8221 ggatgacatt atctgagtct tggtgtttgt gctagcggat gttgaacgtg ctccgtctca
     8281 tggcatcttg tgggggtaga tgcagtaagc tgatatcggc agtctaagca tttggcagtg
     8341 caggggcatc tatgtgtttc gagctccaga tcaggccgta tgttcatgag cgacaaattt
     8401 gtaaatgcgg ttttacccgt agttcattgc ggtaataact tgagtgatat tctggagagg
     8461 acgggtttca tctggtatgc aataagctga cgcaaagttc aaactggcgg aatccgtttt
     8521 tgtttagaga gcagcgatca cgccaaccgc cagagacatg tcttttcttg tcacgtcaaa
     8581 tgggcatccg tagttactag tcatacgatc atagtgccac tagaatctcc attcatccat
     8641 ccagcgctct acaggaagaa acggacggtg ccttatatac gtgttggtat agcttccagt
     8701 gagtagatgc aggctgagca gtgatactta tcaccagtta acgagttacg aagttctttc
     8761 aattgcctca ttgtcaaaat tcatccgagt gtctggactg agagccttat gtgcgtttac
     8821 aggacccata ttctcgcgag gttgagtcat attaacattt cgcaaagcgc gttgatccat
     8881 tgagacttac ctcgggaact tgcatatgac aatgtcggta cccaagtctt gtacgatttt
     8941 ggtggctggt ggtggccctg ccggctcgta tgctgctgca gccctggctc gagagggcaa
     9001 tgatgttgtg cttctcgaag cggatcaaca tcctcggtgc gttccattcc aagttctctc
     9061 agaatccttc acgaagaggg cacagctcaa atgtaagagc taacagcagg tagctatcat
     9121 atcggcgaga gtatgctccc gtcgttgaga ccgctgctgc gatttatcga tctcgaagat
     9181 aagtttgatg cacatggatt tcagaaaaag gtatcctcct cacccaacta ggccaatctt
     9241 tctatcttta ccgaacggct aggctgactg caatttcagc tcggtgccgc tttcaagttg
     9301 acttccaagc gcgaaggatg taagcgatct tgctccatta cgttatttac ctgcaaaacc
     9361 caagaaagtt gagctgaccg acccaagaca ccgatttcat cgcagcccac ggccctagag
     9421 gatactcctg gaacgtggta cgctccgaat ccgacgaaat cctcttcaac catgctcgcg
     9481 aaagcggcgc ccaggccttc caaggcatca agataaacgc aatcgaattc gaaccatacg
     9541 aggaagagta ccccaacgga gaaaaagtgg caaatcccgg gaagcccacg tccgcaaaat
     9601 ggtcgtccaa ggatggcagt tctggggaca tcgccttcaa gtatttggtc gacgcgacgg
     9661 gccggattgg catcatgtcc acaaagtatc tcaagaatcg gcactacaac gagggtttaa
     9721 aaaacctggc catctggggc tattacaaga acaacatacc ttgggcgcag ggtacaccca
     9781 gagagaatca gcccttcttc gaaggcatgc gaggtgagta tacaactcct attcaacacg
     9841 catgatagca cgtcgtgaga tattctaacc gactaattca gacggcgctg gctggtgctg
     9901 gaccattcct ttacacaacg gcacagtctc agtcggagcg gtcatgcgaa aagatctctt
     9961 cttcgaaaag aagaagagtc ttggtgaaaa tgccaccaac acccaaataa tggccgaatg
    10021 catgaaacta tgtcccacga taggagaact gctcgcgcca gccgaattgg tgtcggacat
    10081 caagcaagct acagactatt cgtacagcgc gaccgcctat gccgggccca acttccgcat
    10141 cgtcggagac gcaggctgct tcatcgatcc attcttctct tcgggccatc acttggctgt
    10201 tgccggtgcc cttgcggccg ccgtctccat aaacgcatcc atcaaaggcg actgcaccga
    10261 gtacgaagcc tccagatggc acgcaaagaa ggtagacgag ggttacacat tgttcctgct
    10321 cgtggtcatg gctgccctca agcaaatcag gatgcaggag aacccagtgc tgagcgacgt
    10381 tgatgaagac ggctttgaca gggcattcca gttcctcaga ccaggtgagt ctaagccgtg
    10441 agattcgacc gggaacacac actgacgcct tgtctagtta tccaaggctc cgggtcttca
    10501 gaggcggtta agaagttcac aaaggaggac gtcgcgcaaa cgattgactt tgctgtgcat
    10561 gcgctcaata acatggcgga actggacatg gatatcccgg agcacatgat caatggggac
    10621 aaggagggcg agaatggtgt gacgaatggc aacaatgggg ctgcaaagac ggctggactt
    10681 gcgtcaaaca tggagaagct cacgaatgat gaggagaagg ttctcaatgg tcttcgtatt
    10741 cttggcaagg ctgcgcctgg aggaactctg gcggactttg agggcactgc aatcgatgga
    10801 ctgatgccga gattggaaca tggcaaactt ggcctcaaca aagtttgaga tgggatgctg
    10861 agagagtgtt actgggcttg atgttagagt tctagagtca ttacaaaaaa aacacacggg
    10921 tatcgtacac attccgaaag ccgatgtctc tcacacgcgt caacgttcca cgcattctgt
    10981 gtaactttat tcgcaggaac agagtttgcg aatagagttg tgaaacccga aaacccaacg
    11041 gcattgaggc cggcataaaa catgacgaaa gcaacacacc tcatgaaatt gtgcggtgaa
    11101 atgacaaaaa acaaacttcc gtctgcattt agcatccgga aataagtcct cattgctcct
    11161 gggcatctcg cgtctcacag catgtttgca cgcacggatc aacggatttc gtgttcaatg
    11221 tttccaacaa tcccgatctg aaccaacatg gcaactcaaa acagccaaaa ccagagtaga
    11281 agtggccaat cagagctctg agacatcagc attgtgcagc tgcaatctct tggatgtaac
    11341 agcttgatgc aagtgagatc caaagaggat attgcctact ttgcttctac cgccgtttgg
    11401 attacattgt agagttgcag ggttgagttg cagggttgat gcgcgttctg gtcttggtgc
    11461 atacgacaaa cggcgagacc cacagttgga ccaaaagtag attagtgccg atcatcagat
    11521 gtacctccaa gtcgcgacaa gctcaacttc ctaggttcca gatgtcagag cttcaatgtt
    11581 gccaagggcg gccagtgtcc tgctccatcc ttctcactta ggtcccaaaa atttcaatgc
    11641 tgacagagtc tcgtggctgc atccagattt tcgaattgag ctgagaaagc cctccatgtc
    11701 tgctggcgct ctgtccgttt caacgttgag tggaaacttg caggtacgtg acagtcctta
    11761 cgctaagcct ccttgggtca caaagtgggt catgctactc gtcttgtgta ccagtactca
    11821 gtactccgta ctccgtgctc tgcaccatca cacccgtcaa gcgttcgact gcacttcact
    11881 gcacacgctc acacaaaggc ccatgtcaac tttatgcatg aagtgatcct ggatacggct
    11941 gttgaacaag caaacgggat ctctcacaca cggaccatgc cgagaaagtg acacagatga
    12001 acgcacggga cgatgccccc atcctcacaa tgcctgacac ggttctaact tctggaagct
    12061 gctattgcga attccgtaat ccgtaatccg tacttgccgt ctatatgcag atgacaatcc
    12121 tcgtttccgc ccagagcgaa ccacagtcaa cttcttcaca cgggcatgaa gtagtttcgt
    12181 cagccacatt acgttttctt cctatctgac cccggcagtc cactttgaag cccccaattc
    12241 agtcattgtt ttgtcagggt gcgagggtat tggagttgag acccaatctt tgccggccgc
    12301 cacaatcctc cgagttgagt tgttgaccac accacaccac accacacatc aaacaccatg
    12361 gcaccaagcc aagatttggg cgagcgggac cagcagcagc caccagcgcc ctaccctgct
    12421 gatctcgaaa atggccggta tggcagaata ccaaatgggc atggctctac tactggcaca
    12481 gaaggcagtg gcacccttca actgaacgag aaagacgacg ctactctccg accaaatggc
    12541 agccatgatg tgaaggagga gggccaggag accagcacaa atgtcgttga ctgggatgga
    12601 ccagacgacc cagcgaaccc tcaaaactgg taagtgtcgt tggattttga acttgtttac
    12661 gtgtagtctc gctaccttga tggcatcgca tacgggagca tcaacaggcg aaataataac
    12721 aatgtactaa caaagacgtg aaactaggac actttccaag aaatggctaa atatttccgt
    12781 tgtcggctta attaccttca atgtacctct cgcctcctcc atgtttgcac ccgccgtgcc
    12841 acaactactc caggacttcc acacggataa tgcgtccctt tctacattcg tcgtctcagt
    12901 ttacatcttg ggcttggctg cgtaagtgag gcgctctgat ttcttcattt aacctctgct
    12961 cgtaaatatt aacgtactct actagaggac cacttatact tgccccgatg agcgaacttt
    13021 acggaagact caacgtctac catgtcggca acgtactttt catcatcttt accgttgcct
    13081 gcggcttagc aactaacatt aacatgcttg ttgcatttcg cttcttggcc ggtttagttg
    13141 gagcggctcc cattgctata ggagccggaa caattgcaga cgtcaccaat ttgcaacaac
    13201 gaggaacagc catgtcaatt tggagtctcg ggcctctctt ggggccatcc ataggacctg
    13261 tcatcggtgg cttccttgcg caagccgcag gctggcgttg gatcttttgg ttgctggcga
    13321 ttattgctgg tgccgtcgcc atcatcagct tcttcgtact acaagaaacc catgcgccga
    13381 cgttgttgaa aaggaaaaca aaccgattga gaaaagagac cggaaacatg gcgcttcgat
    13441 caaaacttga cacacaactg ccacccaagg agatgtttct gcgtgccatt gttcggccgt
    13501 gcaagatgct gctcttctcg cccgtgtgcc tcatcctcag tttttactcc gcttttgttt
    13561 atgccttgat ctacttcatg ttcagtacct tttctttcat cttcaaggcc agctatggct
    13621 tcaatcaagg cactgtgggc ctggtctatc ttgcttgcgg tatcggcatg ctgctcggcc
    13681 tcggcattca gcagttgaca ggagatcgca tcagacagag gctcgcagac aagcgcaatg
    13741 gcggcgacca caagccagaa taccgctttc cgcccatgtt catggctggt gggcttctcc
    13801 ccgcgggact tttcatgtac ggctgggcgg tacagcacca cgtacaatgg gcggtgcctc
    13861 ttctgggaac tctcattgcc ggcataggta tctgtatcat cagcatctgc atcaacacct
    13921 acctcgtcga tacatttaca atgtatgctg cttctgcact ggcggcttca gctgtcttgc
    13981 gctcagtgtt tgctgctgtg ttgccgctgt ttgccctgca gatgtataat aaactgggct
    14041 tgggatgggg caatagtctg cttgcttttg ttggcttggg gatgtggccg atcacattcc
    14101 tgttctttgt tcatggtgaa aagttgcgca agaaccccaa atttcagatc aagttttagt
    14161 caacgatgtg tgtgcgaagg attggagagg cgcatgggta cttgttgaaa tggcaaagta
    14221 gaatgggttt taatggtggt tagcttttat tccgcttctt aatatggtag actgatagac
    14281 ggtaactcaa ttcattcaca catatttctt gccgcaatgt tgtgctggtt catttttagt
    14341 tgcagcactc agtaaacgct ccatcgagag cccacaccat gccaaatagt tgtagttccc
    14401 gacgcatata agtgtaatcg ttgctgacat agatcacaag agtaagttta ccaaatgtta
    14461 ccaattcatg ggcgttttgg actttacatt agcacagtcg tcgcgaacag cagaacattt
    14521 cccacaacga tagggtaaga atcgttgctt caaccctgcc cacaaggctg caaagggccg
    14581 cagaagcaac ccacgtatcc acagataact ctggccatgt gatagacacg gatgtgcaca
    14641 atcttgcatc agagtgtatg acgagacaaa cattcagctc gtagggtcgg tggatggcgt
    14701 gccggcgtcg cagttggaag gacgggtcac atcctgcggg tgagtcccat tgttcgtacc
    14761 acctggagca tgcaagtcat gcatgtggag cttcgggata ttcccatgtg gtaataatgg
    14821 ccgaaacacg gaagcaatga tgtgacatga gctggctgag ttgagtggta taaagcagtt
    14881 gatacactgt cactcaaccg tggaaaaagt aatcggcctc gtagaacgtt caagtcatat
    14941 ttcaactaca atacactgtg cagtttcatc gtcaaatggg tcctttaatg ctctattgaa
    15001 cttacaaaat gaattgtctg gccgccatgt ccctgcctca tacgtgattc cgcacgccag
    15061 acgaagccat ccgcctcgtc tcagcaacgc tgaagaaaaa tccatttcta gagatcctcc
    15121 acgttggaaa gaactataac ttcttcctag ctttcttcct caaatcgcca ccatgactca
    15181 tcagtgcctg cagagcctcc accgaacccg tctgcaccgc aaaatgaacc ggcgtccacc
    15241 cagccgcatt cttcgcattc gggttcgccc cgtactcgag taaacgcttc aacacagaca
    15301 ctctgtttct tatcacagca atgtgcagcg gcgtgtttga ctcgctgtcc ggctggtcta
    15361 ctgccgcacc gctcctcagt agcatgtcca ccatgttgtc gtggccgccg tctgcagcaa
    15421 tgtgcagcga cgtttggtag taatcgtccc cttcggtacc gtcatcgcta tcgaaattct
    15481 ccagtgctgc catgtagtgt gtttcgtcag atgggccggg cgaagcggtt tgcggcgtgg
    15541 gaagggctgt cgcgtcttgg tcgtatgtgg tgttggggag ctgtcttcgg tagtggtcgg
    15601 tgttttccca gcggcggttt ttgacgcacg gaattagaaa gtagttgttg atattggatt
    15661 gagaaaagcc gtcgcagttt tctggtagag acatgtgctg cgatggttcg taactgctgc
    15721 cgcggggaga caggttcaga tccgtcatat ccagcctcag gcttactggg tgtcaatgac
    15781 gtcaaacagg agtagtgaag ggagtttggg gcatactcac tgcgactgaa gcggtaggct
    15841 atcgagtggc tgctgaaatt ggccgaggta gctggccgat ggggaagggt ctgtgagtag
    15901 ccattctgcg ctggacgtcg aactttgagg gcgatgtata tctatcgagg aggaaccttc
    15961 atgaatggga tgatgggaaa gatcgtcctt ggtcatagaa tctggtacaa ctgtccctgt
    16021 gctggcttct gcccatgaat cctgagacgg ccgtggttgt atcgctttgt gtccggttgg
    16081 aggcaagcca tgatcgggat tcccagccgt cgctttcgac actgacttgg tctttttctc
    16141 agatcttttg cctatcgtca ttcgagatta gacttcggcc agcgataaaa ttggagaaaa
    16201 agagctatga gagcctttgc tccattcttc atttctactg ccttctcttt tattaccgag
    16261 ggttacttac tgcgaagtct tctttgagca tcccgatttt gtaaccgtcg gcgctcgaca
    16321 gcgcccactc cggataactg atggctgtct ggttggaaac gcagcaacca tgcctcgtcg
    16381 tcattatatt cctgactctc aacaggtggt gttatgtagt gtgcggaggc agttttggca
    16441 actggctgtg aatttgactt tggcatggct tgtactgttg tactgcgcga tttggctcac
    16501 cagatctgat gggctctagc acccggctta ttgatctctt ttgtaagtta aataggtcga
    16561 taacctgtct tgcatcaact ggacgcctcg aggagcaatg aacaactcga gcaagtggtt
    16621 ttgtagttat cttatgcact ttggcgcttg gggtaacatc aagtgtaagc aatgcatgct
    16681 tggtccaccg cggacggttg gctacaacgt gaatgaccct cgttgacttg aagacaagac
    16741 aggggttaat ctgacggacc cataagagac tgacacacat ggcattggag gcggttacct
    16801 ggatggtgat gccgtggcta gtgatgtgtt atgttacggg caatgtgagt tcttcgttgc
    16861 gacttgaaca ctttttttct ttctgtaagg tacaccggca ttctttcaac ccttctagcc
    16921 cccaactgtc cgtgtcacct agcaaaagtc ggcgttctcc aagataggca aaaggtggcc
    16981 ggaaatcgag cagtccatcc cggacctcaa atctccacgg acggcccgcc gccttgcata
    17041 tgttcatcga atgccctgtg tcttgaaaag cacgaaccaa ggctgcgccc gcgacgagga
    17101 tgaaacctgc cacgccatta cggtgctcag tgctccgtgc tcgggcattt tgccacctat
    17161 gacaatgtct ctgtgcgtgt tttgctaact ctgacaacat acttcaagta agatctctga
    17221 tccagacagt gaacaatttg actaaccgtg tgacccggct ctgcgtataa catacccgga
    17281 ggctgagccg ggctcttttg tcagtcctgg gcgtaaaagt tgacgttggg ttcacgacgt
    17341 actgttgggc acgagcgagc tttgtgtcta ttccggtgta tgctatgtat gggtggtggg
    17401 tgtgactgac cctcatgacg gcgggattcg acaagttttc tgccatgttt agtgctttgt
    17461 aaagacgcct gaacatagcg tcgacttgac tgccgggctg tctatccgat gggaaactct
    17521 gtcagaaata agtggtacca cttgcgtgta ataattgcag taatgtatgg aagggagggg
    17581 ttcggttgag aaacccgaga attctagtat caagtcaagg ttacggggtc ctcgtttgcg
    17641 agtaaatcgg cgacttaata ctcctacatg acatgatgtc cccagcttag tatctaatat
    17701 gagctccact gcgggattca ctgtcgcatt taatacacgt tgcccggctt ggcaactcca
    17761 cgcctgcctt cgaactatat agttctctcg tcttccagga tcagctggtg aggcggaaac
    17821 tgcattctgt gaaatggacc tcatgttact cggtgtgcag ccagcgtttc tcgcccactt
    17881 cttgcattag tcattccggt gtgcaggaat tctgcttacg ttttttgccc tttcatcttt
    17941 cttccaggac tagggattcg gctcctacat cacgtactca cagccacgat atcgtgtccg
    18001 tcgggttgct tagggtcctg ttattgccga tccaaagagt attctagtaa gccaatttct
    18061 tgttctggtc tagttcccca cgtcctaatc atggaaggag agcgctgttt tgaactcttg
    18121 agtgccggaa ggtcagcagc cacatctcgg tgcgatccgt tttgagccac cgcctcatgg
    18181 accacgggaa caaggatttc attggcgtaa agggcttttt tggcaaccct tgtttgtctg
    18241 catacgtagc gcaaccgggc acgtagagtg ctgggaactg ccgcttatgg catgaaggag
    18301 cggctggctg gctggatgtc tgcgcgagtg tagtattctg cagagaaaag aggttgatac
    18361 acgtggtagt tgccagcaag agggttacgc ggaagcccga aagtggcgta agccaggctt
    18421 tctatttgga cgaggttggt tttcggggag ccaagcagtg tgaaacttgg cgacaaggat
    18481 aacctgtctt tcctatcttc cctccaagga cgatttcgac aaggttcccc atgtgtcatc
    18541 cggagatcct actggtagtg tcgaatcatc tgaaaaagat aagcataaca tggctaggag
    18601 ggcggaagag agttacgacc ggatcagttt cacttatctc atctgcacca tgctatcacg
    18661 tatgtcaact tgaccttatc ccgtcgccca ggcttgcgtc atgttggaat tcacatgtat
    18721 cgcagaaacg ccacccggtg tctgcagcat attattttcc agcaatctca gcccggtgtg
    18781 aggttacatg cactatccac acatgttcgc tagttgaccg tggcaatcca tccgcaagaa
    18841 aagcctcgtg tcagattaca ttggtagaaa accacccggt agaagttact tgattgcgac
    18901 gggtttgcgc gatcaacgga atgttcgggt aagcgagaac cggaattgga ccagaggcgg
    18961 ccgccttgct taccggcacc gattccgggc ctcgatgatt cgcttgatga actcacatgt
    19021 tttgtattct agaatgaatt acagcatgtt taacgcaaga gtgcaggtgc tttaagctag
    19081 tttcaccgca gcctaggact tggcgtattc cctccagccc gcttatgaat cagaaactaa
    19141 gtacatgccg ctgctttatt tcgactcatg aacctttttt tttttttttt tttttttttt
    19201 tgggtctatt tactgcagtt gaaatgggaa attgttctgc gttgcaaacc agctttccca
    19261 aactctgctc agcagcccac gcaactgaga ccagctgaac actactcaat gcctaccatg
    19321 ccgccttgga tcaatctgct ctctcatgct tgaccagctt cacccatagt gggctcttgg
    19381 cgccgacaat gtatactttt tgcttaatcc agtcactgct ctccttgcag agctcaatgt
    19441 catacgtgaa gacaaacttg gcgagcagca ttctcgcttc atgatacgca agactagatc
    19501 tctgttagca tttgtttaca agcgccaaat atgtagaata gagaccacac ttttttccaa
    19561 tgcagtctct gggccccgct gaaaatgcct gtactgcttc cagtcgatca ttggcaaact
    19621 cagctggagg attttggctc catctctcgg gaatgaactc atgcggacga gcaaaatggc
    19681 taggcgaatg ataagaagcg tactgcgagt aaaagacgac agactgaata tgcatgttag
    19741 atgcgcttcc tgtttccaga agacaggtga tgcagttaga cccatcactt acatcaacgg
    19801 ggagaacatg accatcgagc gtggtccctg gctgaacaac gcggcgagga agaccacccg
    19861 gaacaggggg atacacacga agaccctcct cgatagccat ctgcaagtac tgcagcttag
    19921 gtagggtaat cgtattcatc tcatcggtgg acttgaacgc gcccctcact tcagcctgca
    19981 acttcttcat cttctccgga ttcttgcaca gcaaatacgt gatcgcgctc attagcgatg
    20041 acgtagtttc cgttgcagcc gtgagaagca agaagccatt ttgccgcatc tcgccctttg
    20101 ttaatccgtt accttttgcc tctgcgtgct caaccaatgt ccaaaagtca ggatgactag
    20161 gattgtcatt cgccaaccgg ttcataactc gctcatcaca gaacttgaca tgctccagcc
    20221 gcttcttaat catagacttg ggcataaacg cctcaaaaat agcttgcaga atgggaaaag
    20281 acctcagaac tctccgcatg gcgctgaatc gcacagtggc ggtgatgttc gccagaaaag
    20341 ggtgatactc catgctttca aggtggtgca gggagtcgcc aaacacgcaa tcggcaataa
    20401 agtcaaacgt ggcaaagttg aagaacatga ccatgtcgac ttttcccgcg gtctgacatt
    20461 tctcgtacga ctttgcaacc aacaggtctg tgtacttctt caacagcggc tcctgctcgc
    20521 ggatggcgcg gtcgctaaac gccggggcga agacttttcg ctggcgataa tgctcctcgt
    20581 cgccagcggt caataggcct tcggtaccgt ctttgcgctg gttcttcatg taatatgcct
    20641 tgaagtcctt gggaacaccg ccggctctgg tgttgtggcc gtacacgtcc ttggttgcgg
    20701 ctgtgctgat tgtacttaat tcatcggggg agacgcgaac gtagggaccg tatttgatgt
    20761 gtagcttgta ggtcatggca acctcctcgc cggttaggcg cttgaatgcc aggggaatcc
    20821 gagacgcagc taggtatttt ggtccgggga agtttgcgag ggggtggaaa tagacattgt
    20881 agattgctgt gtagacgaca tatccgagta actgaggcga tacattcatt agccaaaatg
    20941 tcgcttacca acgaaactcg agggagtcta ctcttacaat tgatatcgca attgataccg
    21001 tgaatgcgac tggatgctct tcggccttgg ctaacagacc actgggcaga gagcccctgt
    21061 agccggtggt tgaggttgtg gccagaaatc ccatcttgcg tacacttgtg ccgtcaagct
    21121 cagaccaaca cagttgacac tgaattgaag tatttcaggg aggcttttgg gtatttgacc
    21181 acataagctg aaaacttaca cgttggtcag gatcttggga cgtcgttaca gtatcacagc
    21241 gtggaagggg atcacctcca gggaagccgt caattaacac tattaagatg accaacaagc
    21301 agagatgttc gatgttgttt ggtgcatcca ctgatgaaaa gaccttctag cacttccggc
    21361 attttctctg gagtgctcaa gcaattcctg tcaccaagtc cgcttcaacc cgcaataagc
    21421 ttattgaggc atattttggc acgactatcc gtgtccagca aatcgcctca cacgagatga
    21481 cgatgatcca tgaaaatgac cctgtggtaa gcttatggtc tctcgacatg caggaatctg
    21541 acaatgtctt ggccgtggaa cactcatcgt tagctttctt gcatagcgag ccaagtgttc
    21601 gaagcatcaa cccgtgtcaa tgacaagggt caagtttagc taaccgccat ctttttacga
    21661 tctccgaaat ccgcaaggca caaagttgcc tgccggccgg gattgggttt gtggctgcgc
    21721 cgaaccgcgt cggcattggg tcccggattc atgcagtaag cttacgagca atcagccaat
    21781 gagcatttca gcatatttcg atccttctgc aacccgagat gcgtttccgg tggacccttg
    21841 taaacacaat ttatgatcct ggaagttggg ggctgagttt cgtttttgga ccgagtccca
    21901 tgccgtgtcc cgtccccggc ccatcccaca ttcggccgat aaacaagacg tacaagagtc
    21961 agttagtatt atgcttgcta tgattcggtg tggtatagtg cttaatacgg ccgctagacc
    22021 gtttatgttt taatttccga caggcgcagc gcaatgacgt gtgctgccag tgtcaccatt
    22081 cgtgtcaggc tgtaagctca caggataggg tcaaacagta aactatgcta tctcactgaa
    22141 gatgcaggac gggtaactga aagcgtcgaa ctcagtacaa gtcgagtgcg tcgttatcat
    22201 tgtgaatgcc gcgtacgctg acaagccatg tagcgcaacg tgtcgtgaag tagacgtgga
    22261 actcgggttc gaccaatttg gaaggccgcc tgggctgtca aaaacaatcc tgcttatact
    22321 atctacattg cattcgtgct agctgcacat actttggaat acccatacca gatattctgt
    22381 gaaaaagtac tagtttctta ctgaatatga cggctcttca gtacactgcc gcaatgtgat
    22441 gacatgccga gggcgtatag accaaaccaa caaatgctgt ttgcacccca tttttgtatc
    22501 acgacatgca cgtggagaag gtaagcaaca gagttaatcg aagagctccc atgtcctgaa
    22561 agttaagcct accgcgacga taatggctca tcgcgaatta cagtcaacgt gggtaagcag
    22621 agagctgatg ctgaggatcc gggagtgtaa gccggttgca tgacttcgcc tttctagaag
    22681 tcagcgatgc agtattgtaa ccagtaaatc gaagcttgta acacccctct ccctggcatc
    22741 gacgactgta gccccgcaga ttggttagat tgtagtcatt ctcgataggc gtggctgtat
    22801 atgttcaaac ctcatttgaa gcttccccta cgaactctgt ctctcacgac attattcgtt
    22861 ccttcagcta catctccaat caatatcata tagacagatc cgaacatcgg tcaggcacac
    22921 tcttactctg gtagctttgg atccttagat atcccggtca ggttgcttct gcctacacgg
    22981 caaccaaggg aacaattcct cggcgtagct gccttcatag ctttttgggg acatcgtcag
    23041 gatgccctcc gcaactgccc aagatgctcg ggctcctatt gccattattg gcatgtcatg
    23101 ccgatttccc ggtgacgcag aagatccctt gaagttctgg gacctcttga aagagggacg
    23161 ggaagcctac tctgagaaga ctcaccgata caatgaagaa gcattctacc atccaggagg
    23221 ccaattcaac aacaaacgcc aaaatgtcct gcccgtcaag ggcgggtata tgctcaagca
    23281 ggatccatat gtctttgacg ccgccttctt caacatcacc gccgcggagg cgatctcctt
    23341 cgatcccaag cagcgaatcg ccatggaggt cacatacgag gcgttcgaaa atgccggcat
    23401 gacgcttcaa aaagccgctg gaacaaggac agcgtgctac attggaacct ccatgagcga
    23461 ctatcgagat tccattgtca gggatttcgg caactacccg aaataccacc tcctcggcac
    23521 aagtgatgag atgatttcca atcgaatttc gcacttcttt gacctccgtg gccccagtgc
    23581 aactatcgag acggcttgct cctcaagtca cgtcgcaacg cacattgcct gccaaagcat
    23641 acaatccggc gagtcagata tggccgtcgt tggtggtatt ggcatgctcc tcgtacctga
    23701 aagcaccatg cagctcaaca atctcgggtt tctcagtgcc tttggtcagt ccagagcatt
    23761 tgacgcctcg ggggcaggtt acggccgtgg tgaaggctgt ggcattttca ttttgaagag
    23821 attagacaag gccatggaag atggggacac tatccgtgcc attatccgtg gatcaggagt
    23881 aaactcggac ggatggacac agggcgtgac tatgccctct ggagatgcgc aagcttcctt
    23941 gatcgaatac gtgtacaagt caaacggact ggactatgag ggcacacagt atgttgaggc
    24001 ccacgggacg ggcacaaaag ttggcgatcc aacagaagct gaggcattac atcggacaat
    24061 cggacagcct acaccaaagc gcaagaagct atggatggga agtgtgaaga caaatattgg
    24121 ccatcttgaa gccgctgccg gcgcggcgag catggtcaag ggagttctcg ccatggaaca
    24181 cggcttcatt cccccgaccc ttcatttcaa gaacccgaat ccggctatca agtttgatga
    24241 gtggcaacta ggtgtgccga ctaagttgat gccgtggccg gcttgtcaga ccaggcggat
    24301 gagtaccagc gcctttggga tgggtggcac caacgctcat cttgtgttgg agagaccaaa
    24361 tgaaccagca atacccatac tagaaagagg agcaattggc gtttcgagga agaaccagaa
    24421 gagactcttt gtcttcagca gtcatgacca agcgggcttc aagcgtatat gcgatagact
    24481 cgtcgaacac gttgacaccc ttggccccaa atcatcaaat cctgactact tggccaatct
    24541 tgcacatacc cttgccgttg gccggtcagg tctcacatgg aaaagctcat gttttgcgga
    24601 gaacatcgtc gagctgcgag aacacttgac aagttcttct cttccagagg gcgcagtgcg
    24661 tgccgcgggc ggccaaactc gcatcggctt cgtcttcaca ggtcaaggag cacaatgggc
    24721 gcggatgggt gtcgaactaa tggatcgaaa ggtgtttggc aaatctgtgg ccaagtctac
    24781 tgccttgctg caagaaatgg gctgcgaatg ggatcctgtg gtcgaactgt ccaaatcaca
    24841 gaaggaatct caactggtga aaccggaaat cagccaaccg atatgtacca tcttacaaat
    24901 cgctttgata gatgagctgc gatcctgggg catccggccc gcaaaggtcg tcggtcattc
    24961 tagcggcgag atcgcggcag cttattgcat gggggctctt acacatcgag acgctctcgc
    25021 agcagcatac ttccgtggca aggcatctgc taatgtgaaa cgccgtggag gcatgatggc
    25081 ggttgggaca acgcctgaag atgcgaagaa actcatcacc gagacgaaag cgcaagcaac
    25141 tgttgcctgt gtcaactccc caagaagcat tacactgtcc ggtgatgtgg atgcgctgga
    25201 ggctcttcga gagacttttg agaaacaggg agtctttgct agaagactca aggttgacgt
    25261 agcataccac tcttcacata tgcgctcttg cagtgcagag taccagtcgt caatcatgga
    25321 cctggaacca agtgagcttg atggtgcaaa cgagtcaaag gaacccattc tcatggtatc
    25381 cagcgtaaca ggcggcctag ttgatgctga ggcactgggg ccgtactact ggatccgtaa
    25441 cttgatctct ccggtgctct tttcagacgc tctcaaggag ttggtatgcc ctgctgacag
    25501 cggcggcagt agtgacgtcg atatgctcat cgaaatcggt cctcatagtg ctttgagagc
    25561 gcctatcgag cagatactat ctcaccacga catcaaaaac gtcgagtatg cgtcaatgct
    25621 cactcgtggg gagtctgggt cagaaacaat cctcggcttt gccgcagagt tattccgccg
    25681 tggcgtgccg tttgacatcg ccaaagcaaa cgatgacgct caatgccgtc tcttgactga
    25741 cctacctcca taccccttca accacagtca acaatttcgg gcagagtcac gtcttcagag
    25801 agaaactctt acccagcaaa atcccaccaa gagtctcatc ggcgctgagc ggccgagcct
    25861 tgacgagcat gagcgcgtct ggcgtgggtt catcaacctt gatgatgagc cttggctacg
    25921 agaccacacc gttggctcta cggtgctctt ccctggtgcc gccgtcatca ccattgtcct
    25981 tgaagccgct caacaaatgg ccgaagcagg gaaaacaatt cgttccctga cactgcgaga
    26041 catttccttc atggccatga tgacactgct ggagggtacc cctaccgagg tcatcaccca
    26101 tgttcgaccg catctcgtcg ccacaacggg aactacgccg gcgacctggt gggaatttac
    26161 tgtctcctcg tgcaccggcg ttacgagcaa cgttcgtaat aattgccgcg gtttattctc
    26221 catcaactat gaggactctc gcagctcaca catggagatg gagctcgaaa ggtttgaagg
    26281 cgatcgcgtc gcaacctatc accagatcaa aaaggaatgc gtggaggtta tttccaagca
    26341 agccttctat gataccctag ccagatccgc cctcgcgtac ggccctcatt tccaaggagt
    26401 tgacaactgc cgccccggca acggccagac agcgttcgaa gtcatcgtca gcgatcttgg
    26461 cgagacgttc aacaaggaca aattgaccag gccgttcctc atccacggtg gaacgctcga
    26521 ctccattttc caagcgtggg tgggtagcac caaggatagc aacggacccg gtagctttgg
    26581 tttcgaaaag ccattgttgc cgaagagtat tggggagctc gaaatttccc tcgacttccc
    26641 tggtgaggtt gggtactcgt tgaatggcct cagtacttct aaaaaacatg gtttcagcga
    26701 gtggtctact gatattacca tgttcgaccg aaacgtgtcc aagctgcttt tgtctgttaa
    26761 agacttccac ttggctgagc ttgaggtgga agatgcggac cggccagata gaacggagca
    26821 tgttgatgtt gatccggctg agatatcttc tgagccaaag tggaactatg ctcttgactt
    26881 catgagtaca caggaaatca agcaagttgt agaaactgca tcttcttcgg acgataagct
    26941 catgcaggta cgtttccgca tgacatgatt tcaggtctgt gacaagtcac taacacacaa
    27001 cacagtttat ctccttggca atacaccaac gaccaaatct cgagattcta gagctggttg
    27061 aaagcgcgaa tcagctgcgt cagacagccg tatcaaagct acccaggggc agactcctcc
    27121 caaaccaggc cagctgtgcg atacttggtg gtgactatga caataacaac gaatccgcag
    27181 ctgcctttgg tcgaattttc ggccttgata gttccgaagc tgtgccatct gatgttgcgc
    27241 ctgctgatct agtcattgct aacttcaaca tcagtaactt ggaggatatt gcagagcggc
    27301 tcgttgttct tgccaagcct gaagcaagaa tactattgat cgccgacaaa aaggtcgatt
    27361 caagcgtcac ttcactcgct gacaagggct tcgaccttgt cttcagcaca gaagcggact
    27421 ctgaatcact ttctctgtac tgttttggca agaaagaaga accccagcct gaacgactca
    27481 ccaacggctc aactggacaa gaggtcgtta tacttgaacc gtcttccttg tctgcagaat
    27541 cggaccgctt ctccaaggac cttcaacatg cgcttgacaa cattggctac aacgtgtcta
    27601 ccgtgacgga cattcatggt gcgcatgctg ctaaggcgag gatctatgtg tccctcctcg
    27661 aaattgagca gcccgtgtta gagaacctct cacagtctga atttgaaggt cttcgtgact
    27721 tgttgttgaa ttgcgaccgc cttctgtgga tcactcgtgg tgatggcccg tcactccagc
    27781 tggtcgacgg cttctcgaga accataagaa gcgagtttgc tggtgtggaa ttccaagttc
    27841 tacatcttag tggcaagaac tcccggcagg gcccatcgtt agcagcacag atcgtcttca
    27901 agcaaagcac ggaaagcgag ttcagagagg atgacggaca cttgcaaatc tcgcggtggt
    27961 atagaagcgt cgaagaggac gaccacatac gcaaccatct tctggactcc atccgaacag
    28021 tgagcctgcc ggtgggcgga aatatcgagg acaattcctc ttaccgtctt gctgtcggca
    28081 agcctgggct tttgaacaca ttacattttg tgtccgacga taacacagaa gcccctcttg
    28141 cagacaacga ggtcgagatg caggtcaaag ccagcggcat caacttccgc gacatcatgg
    28201 gctccatggg tcttctcccc gtgtctggca tcggccaaga agcaagtggt atagtcgtca
    28261 gggtagggaa actaggggcg tcatcactca aaccaggtga tcgcatcagc accctgacgg
    28321 tgggaggaac acacgcaacc aggatccgct gcgactaccg ggttgcgaag aagattcccg
    28381 agggaatgtc gtttgaagag gcagcaggaa ttcccgtcgt ccactgcacg gcatactacg
    28441 ctctcgtcaa gttggccaag cttcgtcccg gccaatctgt gctgattcac gccgcggctg
    28501 gcggcaccgg acaagcggct ctacagttgg cgaagcatct tggcctgacc atctttgcta
    28561 ccgtaggcac tgatacgaaa cgagcgctca tcagagaaaa gtatggagtc cctgacgaaa
    28621 acatattcca ctcccgggat ggcagcttcg tcaagggtat cgagcgagca accaacggcc
    28681 gcggagtcga ctgcgttctc aactccttgt cgggtgagct cttgcgatta tcttggggct
    28741 gccttgctac ttttggtacc tttgtcgaga ttggtctgcg ggacatcacg gacaacatgc
    28801 gtcttgacat gaggcccttt gccaagagta ctacattcag cttcatcaac atggtgacct
    28861 tgcttcagga gaaccccgat gctatggggg agatattgga gagcgtgttc gagatgattc
    28921 accaaaacgt acttcagccc gtcttcccag ttactgtcta ccccgtcggg aaggttgaag
    28981 aagcgttccg cctcatgcag caaggcaagc atgtaggcaa gatgatcttg tcgtttgctg
    29041 caggtgatgc cagggccccc gttctttgca gagccaaaga ttcattcaaa ctcgacccca
    29101 acgcgacgta tctcttcatc ggtggtcttg gcggcctggg tcgcagcatg gccgtcgggt
    29161 ttgttgcctg cggtgccaga aatattgcat tcctctcgcg atcaggcgac agcaagccag
    29221 aagcaaaggc cgtcgtggac gagctgagag aacttgggac tcgagttcag gtgtacctcg
    29281 gcgatgtctc tgacgaagcc tctttccgtg gtgccatgga acaatgctct cgggagctac
    29341 cgccagtgaa gggcgtgatc caaatggcca tggtgcttcg cgatgtggta tttgaaaaga
    29401 tgaagtacga tgactggacg accgggttac ggccaaaggt acaaggcact tggaacctgc
    29461 atactttctt cgacaaagat cgcccactgg acttcatgat cttcttctca tccattgcag
    29521 gcgtcttcgg caacccaagt caagcgcagt atgccgcagg caacacgtat caagactcac
    29581 tggcgaaata ccgccgcgac agaggtctga aagccgtttc tgtcaaccta ggcatcatgc
    29641 gagacgtagg cgtgatcgca gaaggcgact cgcacttcat gcaacagtgg gaagaggtgc
    29701 tgggcattcg cgaacctgct ttccatgcgc tcatcaagag catcatcaac ggtcaactgg
    29761 agaccagcaa cattcgagaa gctgccaagt gccccgtgca ggtcaccgtt ggtttgggta
    29821 ccggcgacat cctggcacgg aacaagatca gagagccaga ttacttccgc gaccctcgtt
    29881 tcggggcctt ggccgtctgc agcagcacat ccaccgccgc agccagttca ggagaaaacg
    29941 gcgtgtccat agcatcccag ttagcaggct tgagcaacga ggcagatccg gaggaggcag
    30001 caggacccat catcacaaaa gctctggtga gcaagctggc gaagattctg caagtgccgc
    30061 ccagcgagat cgactctagc cggccgatgt atcggtatgg cgtggattct ctggtggcga
    30121 ttgaggtgag gaactggatt acgaaggaga tgagtgccaa tatgtcgctg atggatattc
    30181 tgggtgcgat gccgatggag cagtttgcgg tgcagattgc aaagaagagt aagttggtgg
    30241 gaggttcttg atggttgtgg gagtcatgtt ttagttggcg ggtgttatca atataaatgc
    30301 gggatacaga agtcaataaa taaaggttgc gactttgcaa tggaaccaat gtcactggta
    30361 gaggaggtac agactaggct gtacggcaat gttttaaacg gagctgataa tccatgggct
    30421 ttgcaggatt aatttcgttg ttatggttac aattcgcgct ctgcgtcctc tgctgtacac
    30481 agctccctat gtgtagtacc acagtcgtta aaaaagccag ctctagtact ggaaatatgg
    30541 taactaaatg cggtttaaac agaaacagtc tacaggttac cagctaatct caggtctacg
    30601 gtatctcgcg ttaggtctag gtagggcaaa agcgtagcaa aatagtatcg gcagctaact
    30661 attagcagtc tagaagggtc aagataacta ttgtgtcacc gaaagctgca cacaccaata
    30721 attaagacca acaacaccat gaacaataac atgggaaatg catctctcgt gagctcacaa
    30781 ttatttcatc aattattaca aggttaacta ctttatatgt gataaagagc gtatcaagta
    30841 gttacatcaa ggcatcgtgt attaggtgtc gtagcagata aataaagcaa gctatctgag
    30901 caagacctag ttctcttata ccctgcatac cttccaatcc ttattgacct aacaccccct
    30961 tttctctcaa cgacaccttt tctccgtgag tgcaaaatcg cccacacact ataacaggca
    31021 gccatctttc tcaccagata aactcaaaat acaaagacca atccactgtt caatttacct
    31081 gtagctagca gcagctttaa cagttgtgat gccggaccaa acgtacacta gctactttac
    31141 ggcgagaatg tagacaagtt gtcttatctc atcgggtgaa tcgatagcag ttgccatcag
    31201 cgccgcagaa agcagtacca ggcaagcagc acgcacgggc gcagcaagta ggcgcctcgt
    31261 tgccgcacca aaagccaaac gagcaccacc gggcattggg ggcggcaaca gcgttgatgt
    31321 cgccagcgaa tt
//
