BGC0000135: reveromycin A biosynthetic gene cluster from Streptomyces sp. SN-593
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Location: 1 - 104,853 nt. (total: 104,853 nt).
This entry is originally from NCBI GenBank AB568601.1.

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core biosynthetic genes
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000135
Short description reveromycin A biosynthetic gene cluster from Streptomyces sp. SN-593
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB568601.1
Compounds
  • reveromycin A
Species Streptomyces sp. SN-593 [taxonomy]
References
Chemical products information
reveromycin A
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C36H52O11
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAK64627.1
 1 - 909 (-) putative amidohydrolase
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  • BAK64628.1
 954 - 1637 (-) hypothetical protein
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  • BAK64629.1
 1874 - 2899 (-) putative amidohydrolase
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  • BAK64630.1
 3134 - 3793 (+) putative transcriptional regulator
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  • BAK64631.1
  • revO
 4375 - 5676 (+) putative transporter
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  • BAK64632.1
  • revP
 5725 - 6399 (-) putative transcriptional regulator
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  • BAK64633.1
  • revQ
 6591 - 7424 (-) putative transcriptional regulator
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  • BAK64634.1
  • revR
 7941 - 8942 (-) putative 3-oxoacyl-ACP synthase
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  • BAK64635.1
  • revS
 8942 - 10681 (-) putative CoA ligase
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  • BAK64636.1
  • revT
 10719 - 12050 (-) putative CoA reductase carboxylase
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  • BAK64637.1
  • revB
 12672 - 28304 (+) polyketide synthase
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  • BAK64638.1
  • revC
 28332 - 39506 (+) polyketide synthase
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  • BAK64639.1
  • revE
 39521 - 40624 (+) putative dehydrogenase
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  • BAK64640.1
  • revF
 40693 - 42144 (+) putative aldehyde dehydrogenase
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  • BAK64641.1
  • revG
 42227 - 43048 (+) dihydroxy ketone synthase
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  • BAK64642.1
  • revH
 43118 - 44641 (-) putative FAD dependent oxidoreductase
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  • BAK64643.1
  • revI
 44684 - 45877 (-) putative monooxygenase
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  • BAK64644.1
  • revJ
 45944 - 46954 (-) spiroacetal synthase
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  • BAK64645.1
  • revK
 47347 - 48279 (+) putative malonyl transferase
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  • BAK64646.1
  • revL
 48311 - 49384 (+) hypothetical protein
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  • BAK64647.1
  • revM
 49561 - 50523 (+) putative quinone oxidoreductase
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  • BAK64648.1
  • revN
 50747 - 51664 (+) putative thioesterase
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  • BAK64649.1
  • revA
 52185 - 71039 (+) polyketide synthase
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  • BAK64650.1
  • revD
 71116 - 92208 (+) polyketide synthase
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  • BAK64651.1
  • revU
 92596 - 95367 (+) putative transcriptional regulator
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  • BAK64652.1
 95517 - 96494 (-) hypothetical protein
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  • BAK64653.1
 96795 - 98486 (+) putative transporter
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  • BAK64654.1
 98486 - 99700 (+) putative transporter
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  • BAK64655.1
 99718 - 100890 (+) putative peptidase
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  • BAK64656.1
 100893 - 101957 (+) putative oxidoreductase
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  • BAK64657.1
 101954 - 102976 (+) putative dehydrogenase
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  • BAK64658.1
 102995 - 103888 (+) putative hydrolase
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  • BAK64659.1
 103885 - 104853 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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