MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AAC01740.2 putative_cytochrome_P450_monooxygenase BGC0000136.5 PKS 100.0 100.0 763.0 9.41e-282
AWH12632.1 Rmp16 BGC0001759.3 PKS 94.0 100.0 717.0 4.11e-263
WP_003071775.1 cytochrome_P450 BGC0002009.4 PKS 79.0 100.3 616.0 6.31e-223
ABV97165.1 cytochrome_P450 BGC0000137.3 PKS 74.0 100.3 578.0 5.55e-208
AQZ61467.1 cytochrome BGC0002892.1 NRPS:Type I 56.0 97.2 399.0 1.33e-137
ASZ00142.1 cytochrome_P450 BGC0001785.5 PKS 54.0 100.0 396.0 3.45e-136
QQZ01646.1 cytochrome_P450 BGC0002497.3 other:other 50.0 96.4 330.0 2.29e-110
ATY46598.1 cytochrome_P450 BGC0001666.3 PKS 47.0 96.7 319.0 1.9e-106
QKG20138.1 cytochrome_P450 BGC0002124.3 PKS:Type I 48.0 100.0 314.0 1.97e-104
AJW65404.1 cytochrome_P450_epoxidase BGC0001195.3 NRPS:Type I+PKS 49.0 94.1 309.0 6.91e-103
ACO31280.1 PtmO5 BGC0001140.5 terpene:Diterpene 46.0 99.2 311.0 1.13e-102
WDT53642.1 cytochrome_P450 BGC0003042.1 NRPS:Type I+PKS:Type I 45.0 99.2 308.0 6.5e-102
BBA66514.1 cytochrome_P450 BGC0001495.3 PKS 47.0 99.5 304.0 1.27e-100
ADU86001.1 putative_cytochrome_P450 BGC0000165.4 PKS:Type I 47.0 99.5 301.0 3.57e-99
ATL73037.1 cytochrome_P450_hydroxylase BGC0001807.4 NRPS:Type I+PKS 47.0 101.5 300.0 5.71e-99
ATW52508.1 cytochrome_P450 BGC0003049.1 PKS:Type I 45.0 94.1 299.0 5.95e-99
AGC09527.1 cytochrome_P450 BGC0001183.5 PKS 47.0 101.5 300.0 6.07e-99
MCG8971279.1 cytochrome_P450 BGC0002860.1 terpene:Diterpene 45.0 99.5 297.0 1.21e-97
ATL73031.1 cytochrome_P450_hydroxylase BGC0001807.4 NRPS:Type I+PKS 46.0 101.3 296.0 2.43e-97
AHH99927.1 cytochrome_P450_hydroxylase BGC0000002.5 PKS 45.0 93.3 292.0 1.16e-95
TXJ86095.1 cytochrome_P450 BGC0002789.2 PKS:Modular type I 44.0 99.2 290.0 4.11e-95
ASZ00144.1 cytochrome_P450 BGC0001785.5 PKS 45.0 100.5 290.0 4.37e-95
TGZ15162.1 cytochrome_P450 BGC0002032.4 PKS 44.0 99.2 289.0 1.16e-94
BAQ25499.1 cytochrome_P450 BGC0001288.5 PKS 46.0 99.7 287.0 5.99e-94
BAE93734.1 putative_cytochrome_P450-like_protein BGC0000164.5 PKS 46.0 93.3 286.0 1.91e-93
ATW51260.1 cytochrome_P450 BGC0002788.2 PKS:Modular type I 44.0 99.2 285.0 5.23e-93
BAP82653.1 cytochrome_P450 BGC0001148.5 NRPS:Type I+ribosomal:RiPP 45.0 99.5 286.0 9.15e-93
ACY01396.1 hydroxylase BGC0000177.5 PKS:Type I 43.0 97.2 283.0 4.7e-92
TGZ15169.1 cytochrome_P450 BGC0002032.4 PKS 46.0 92.8 281.0 1.41e-91
QUQ72343.1 cytochrome_P450 BGC0002349.3 PKS:Type I 43.0 99.0 280.0 4.62e-91
QGA70089.1 cytochrome_P450 BGC0002517.3 PKS 42.0 97.2 280.0 4.76e-91
AZM57027.1 cytochrome_P450 BGC0002314.3 NRPS:Type I 45.0 98.7 280.0 4.98e-91
ATW51257.1 cytochrome_P450 BGC0002788.2 PKS:Modular type I 46.0 92.8 280.0 5.62e-91
BAC68123.1 cytochrome_P450_hydroxylase BGC0000059.5 PKS 44.0 99.2 279.0 1.32e-90
TXJ86102.1 cytochrome_P450 BGC0002789.2 PKS:Modular type I 46.0 92.8 279.0 1.58e-90
ASZ00146.1 cytochrome_P450 BGC0001785.5 PKS 43.0 100.3 276.0 1.4e-89
ANH11400.1 SceE BGC0001770.4 PKS 42.0 96.9 276.0 1.73e-89
ADM46355.1 cytochrome_P450-like_protein BGC0000106.5 PKS 42.0 99.7 275.0 2.8e-89
AYU66269.1 TjhO6 BGC0002461.2 PKS 43.0 99.0 275.0 3.35e-89
AEC13073.1 fosG BGC0000060.5 PKS 41.0 98.7 275.0 4e-89
QGA70088.1 cytochrome_P450 BGC0002517.3 PKS 42.0 100.3 275.0 4.12e-89
AJI44171.1 cytochrome_P450_hydroxylase BGC0001193.5 NRPS:Type I 42.0 99.7 275.0 5.17e-89
ANH11399.1 SceD BGC0001770.4 PKS 41.0 97.2 274.0 1.46e-88
AWH12672.1 Rmp0 BGC0001759.3 PKS 43.0 99.7 273.0 1.53e-88
QBG82530.1 cytochrome_P450 BGC0002587.2 PKS 42.0 99.7 273.0 3.44e-88
WP_003060232.1 cytochrome_P450 BGC0002009.4 PKS 43.0 99.7 271.0 1.21e-87
AKA59077.1 cytochrome_P450 BGC0001619.5 PKS 44.0 99.5 271.0 2.69e-87
MCC5036791.1 cytochrome_P450 BGC0002638.3 NRPS:Type I 44.0 94.3 270.0 7.31e-87
AFI57027.1 cytochrome_p450 BGC0000133.5 PKS 40.0 97.9 269.0 1.19e-86
QVN25654.1 P450_monooxygenase BGC0002363.3 ribosomal:RiPP 40.0 97.2 268.0 1.53e-86
ABV97150.1 cytochrome_P450 BGC0000137.3 PKS 41.0 102.1 268.0 2.8e-86
AKA59450.1 cytochrome_P450_hydroxylase BGC0001203.4 NRPS:Type I+PKS 42.0 99.5 268.0 3.44e-86
AZM50113.1 cytochrome_P450 BGC0002702.3 NRPS:Type I 43.0 99.7 268.0 3.44e-86
AEW98143.1 putative_cytochrome_P450 BGC0002642.2 other:other 42.0 101.5 266.0 9.98e-86
OKI81364.1 cytochrome BGC0002478.3 PKS 42.0 99.2 265.0 3.74e-85
AAC01709.1 putative_cytochrome_P450-like_protein BGC0000136.5 PKS 42.0 99.7 263.0 1.21e-84
ABC87513.1 cytochrome_P450_monooxygenase BGC0001011.5 NRPS:Type I+PKS 41.0 97.7 263.0 1.76e-84
ctg1_orf24 BGC0001013.5 NRPS:Type I+PKS 41.0 97.7 263.0 1.76e-84
AAN85514.1 cytochrome_P450_hydroxylase BGC0001101.5 NRPS:Type I+PKS:Type I 41.0 99.7 263.0 1.87e-84
ATY69573.1 cytochrome_P450_oxygenase BGC0001611.4 PKS:Type I 42.0 99.5 263.0 2.23e-84
CQR60498.1 Rif-orf0(cero)_homologue,_Cytochrome_P450 BGC0001287.5 PKS 41.0 98.7 262.0 4.96e-84
AAT09797.1 NocL BGC0000395.5 NRPS:Type I 42.0 96.9 261.0 1.44e-83
ARM20275.1 cytochrome_P450 BGC0002948.1 PKS:Type I 39.0 97.4 260.0 1.65e-83
AVI57422.1 AbmV BGC0001694.4 PKS 41.0 100.0 260.0 2.49e-83
CAN89640.1 putative_cytochrome_P450_hydroxylase BGC0001070.5 NRPS:Type I+PKS:Type I 39.0 101.0 260.0 2.95e-83
AAF71771.1 NysN BGC0000115.5 PKS:Type I+saccharide:hybrid/tailoring 44.0 94.9 259.0 4.04e-83
AUO16421.1 cytochrome_P450 BGC0001700.5 PKS 39.0 97.7 259.0 4.29e-83
AAY28237.1 HbmP BGC0000074.5 PKS 40.0 99.5 259.0 5.54e-83
WMD04162.1 cytochrome_P450 BGC0002988.1 PKS:Type I 41.0 97.4 256.0 9e-82
ABA41523.1 cytochrome_P450_hydroxylase BGC0000722.5 other:cyclitol+saccharide 43.0 91.3 253.0 3.33e-81
AAO06929.1 GdmP BGC0000066.5 PKS 40.0 97.4 254.0 3.47e-81
ARE67844.1 AbsV BGC0001492.5 PKS 40.0 97.7 254.0 4.9e-81
ABI93790.1 GdmP BGC0000068.5 PKS 39.0 99.5 253.0 1.06e-80
QXL90821.1 cytochrome_P450 BGC0002426.3 NRPS:Type I 39.0 99.7 253.0 1.23e-80
CBA11565.1 cytochrome_P450 BGC0001046.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 41.0 100.5 253.0 1.54e-80
ATY46590.1 cytochrome_P450 BGC0001666.3 PKS 41.0 97.4 253.0 2.51e-80
AWH12921.1 StmP2 BGC0001784.5 PKS 42.0 100.3 251.0 4.46e-80
WDT53621.1 cytochrome_P450 BGC0003042.1 NRPS:Type I+PKS:Type I 37.0 104.4 253.0 4.81e-80
AVX51103.1 nysN BGC0001709.5 PKS 42.0 100.5 251.0 1.12e-79
AAF81737.1 putative_p450_monooxygenase_EncR BGC0000220.4 PKS:Type II 40.0 100.5 251.0 1.22e-79
WP_016640231.1 cytochrome_P450 BGC0002000.4 PKS 38.0 99.5 250.0 1.4e-79
WP_208613467.1 cytochrome_P450 BGC0002007.2 terpene 38.0 99.0 250.0 1.98e-79
AAK81831.1 P450-related_oxidase BGC0000326.5 NRPS:Type I 41.0 100.5 250.0 2.16e-79
QIC03931.1 EncR BGC0002366.2 PKS 40.0 100.5 250.0 2.43e-79
BAK64643.1 putative_monooxygenase BGC0000135.5 PKS 38.0 96.9 249.0 4.31e-79
ADC79647.1 TamI BGC0001052.5 NRPS:Type I+PKS:Type I 40.0 94.9 249.0 4.81e-79
ATY69582.1 cytochrome_P450_oxygenase BGC0001823.4 NRPS:Type I+PKS 40.0 100.3 249.0 5.89e-79
AVV61990.1 cytochrome_P450 BGC0001477.5 NRPS:Type I+PKS:Type I 37.0 104.4 249.0 7.52e-79
AEK75493.1 cytochrome_P450 BGC0000001.5 PKS:Type I 39.0 99.2 247.0 2.34e-78
AAZ77695.1 ChlE2 BGC0000036.5 PKS:Type I+saccharide:oligosaccharide 42.0 99.2 247.0 2.48e-78
BAC68122.2 cytochrome_P450_hydroxylase BGC0000059.5 PKS 41.0 96.4 246.0 5.84e-78
QLG04877.1 PulP BGC0002374.2 PKS 39.0 97.7 246.0 8.72e-78
ACF35462.1 MbcS BGC0000090.4 PKS 38.0 100.5 246.0 8.97e-78
ABB69764.1 PlaO5 BGC0000654.4 terpene:Diterpene+saccharide:hybrid/tailoring 40.0 97.4 246.0 9.49e-78
TGZ15161.1 cytochrome_P450 BGC0002032.4 PKS 40.0 96.4 246.0 1.16e-77
TXJ86094.1 cytochrome_P450 BGC0002789.2 PKS:Modular type I 39.0 97.4 245.0 2.31e-77
AGN74891.1 P450-like_monooxygenase BGC0000459.5 NRPS:Type I+PKS:Trans-AT type I 40.0 101.0 244.0 2.6e-77
QBF51800.1 cytochrome_P450 BGC0001856.4 PKS:Type I 38.0 94.6 244.0 6.67e-77
BAQ21932.1 putative_cytochrome_P450_hydroxylase BGC0001204.5 PKS 40.0 97.7 243.0 9.41e-77
BAJ16472.1 cytochrome_P450 BGC0000058.5 PKS 39.0 100.3 243.0 2.4e-76
BAF92583.1 cytochrome_P450_monooxygenase BGC0000118.5 PKS 39.0 99.5 242.0 2.97e-76
ACJ24857.1 putative_cytochrome_P450_monooxygenase BGC0000119.5 PKS:Iterative type I+saccharide:hybrid/tailoring 39.0 99.5 242.0 2.97e-76
RSO11790.1 cytochrome_P450 BGC0002637.3 NRPS:Type I 40.0 93.8 241.0 8.1e-76
UMP03495.1 NmvS BGC0002649.2 NRPS:Type I+PKS 39.0 99.7 241.0 8.1e-76
UPN68103.1 putative_cytochrome_P450 BGC0002672.2 PKS 42.0 92.8 241.0 8.57e-76
AWH12932.1 StmP4 BGC0001784.5 PKS 39.0 100.8 241.0 1.23e-75
ABM21756.1 PdmJ BGC0000256.3 PKS 40.0 97.7 240.0 1.74e-75
BCN92192.1 cytochrome_P450_hydroxylase BGC0002958.1 PKS:Type I 38.0 99.5 240.0 1.99e-75
ABG02268.1 SalC BGC0000143.5 PKS 40.0 101.3 239.0 5.97e-75
AEK75512.1 cytochrome_P450 BGC0000001.5 PKS:Type I 40.0 96.9 238.0 8.72e-75
AFO85454.1 P450-like_monoxygenase BGC0000391.5 NRPS:Type I 38.0 96.9 239.0 1.32e-74
BAJ52677.1 putative_cytochrome_P450 BGC0000222.5 PKS 40.0 98.2 238.0 1.63e-74
CQR60480.1 Rif-orf4_homologue;_Cytochrome_P450 BGC0001287.5 PKS 39.0 97.7 237.0 1.64e-74
ctg1_orf528 BGC0001199.5 PKS 38.0 100.8 237.0 2.97e-74
ANY57978.1 Cytochrome_P450 BGC0001369.3 PKS 39.0 98.5 237.0 2.97e-74
ARE67841.1 AbsX BGC0001492.5 PKS 38.0 100.5 236.0 4.31e-74
QLG04865.1 PulD BGC0002374.2 PKS 39.0 97.7 235.0 9.93e-74
AEZ53958.1 putative_cytochrome_P450 BGC0000144.5 PKS:Type I 37.0 100.5 235.0 1.35e-73
CBG74929.1 putative_monooxygenase BGC0002808.2 PKS:Type I 39.0 96.7 234.0 2.94e-73
CBW54668.1 putative_cytochrome_P450 BGC0000971.5 NRPS:Type I+PKS:Type I 39.0 100.0 234.0 3.28e-73
BAH02272.1 cytochrome_P450 BGC0000126.5 PKS 38.0 100.5 234.0 4.26e-73
QOD95001.1 PldB BGC0002102.2 PKS 38.0 100.5 233.0 6e-73
AZM50112.1 cytochrome_P450 BGC0002702.3 NRPS:Type I 40.0 93.1 233.0 6.06e-73
RSO11549.1 cytochrome_P450 BGC0002637.3 NRPS:Type I 40.0 97.4 233.0 6.89e-73
QZA73303.1 cytochrome_P450 BGC0002385.3 PKS 38.0 99.2 233.0 1.11e-72
OLZ52453.1 cytochrome BGC0001462.5 NRPS:Type I 39.0 97.4 232.0 1.63e-72
QIC03957.1 CyaH BGC0002347.3 other:other 39.0 99.0 232.0 1.98e-72
QIC03958.1 CyaI BGC0002347.3 other:other 39.0 98.7 232.0 2.72e-72
AAM97370.1 RubU BGC0000266.5 PKS 39.0 95.1 232.0 2.9e-72
CBG70274.1 putative_monooxygenase BGC0002089.2 NRPS:Type I 37.0 96.4 231.0 2.99e-72
BAJ52696.1 putative_cytochrome_P450 BGC0000222.5 PKS 37.0 100.0 231.0 8.1e-72
QNL10608.1 Cytochrome_P450 BGC0002514.3 PKS 38.0 97.7 231.0 8.48e-72
UUG66750.1 Cmx25 BGC0002879.1 NRPS:Type I 39.0 100.0 231.0 8.48e-72
AWR88406.1 putative_cytochrome_P450 BGC0001522.5 PKS 37.0 97.9 230.0 9.08e-72
QIQ28629.1 Nbc33 BGC0002541.2 other:other 38.0 93.8 230.0 1.43e-71
sipO1 BGC0001452.5 PKS 37.0 97.9 229.0 1.8e-71
AAQ84164.1 PlmS2 BGC0000123.5 PKS 38.0 100.8 229.0 1.85e-71
ABV83225.1 CppN BGC0000116.5 PKS 39.0 99.2 230.0 1.93e-71
QHZ99331.1 cytochrome_P450 BGC0001875.4 PKS:Type I 38.0 97.4 228.0 2.06e-71
ATW47931.1 cytochrome_P450 BGC0003049.1 PKS:Type I 39.0 97.4 230.0 2.8e-71
AEC13076.1 fosJ BGC0000060.5 PKS 37.0 99.2 229.0 3.27e-71
AAR16519.1 RimG BGC0000138.5 PKS 39.0 94.6 229.0 3.27e-71
WP_003985474.1 cytochrome_P450 BGC0002106.3 PKS:Modular type I 39.0 94.6 229.0 3.27e-71
AXG22415.1 Cytochrome_P450 BGC0002024.3 PKS:Type I 38.0 99.7 228.0 6.1e-71
KZM73518.1 hypothetical_protein BGC0000632.5 terpene+saccharide 37.0 100.3 228.0 7.93e-71
WP_102918849.1 cytochrome_P450 BGC0002104.3 NRPS:Type I+PKS:Type I 39.0 99.7 228.0 8.49e-71
BAC76484.1 P450_hydroxylase_LkmF BGC0000085.5 PKS 38.0 99.0 228.0 8.83e-71
CAM34359.1 putative_cytochrome_P450_dependend_monoxygenase BGC0000242.5 PKS 38.0 99.7 228.0 1.03e-70
OKI81353.1 cytochrome BGC0002478.3 PKS 36.0 100.3 228.0 1.18e-70
AAQ82557.1 FscP BGC0000034.5 NRPS:Type I+PKS 39.0 95.4 227.0 1.23e-70
AAK81832.1 P450-related_oxidase BGC0000326.5 NRPS:Type I 38.0 97.2 228.0 1.39e-70
CAE53361.1 OxyB_protein BGC0000440.5 NRPS:Type I 38.0 93.1 227.0 1.41e-70
CAC17503.1 putative_cytochrome_P450 BGC0000324.5 NRPS:Type I 38.0 100.5 227.0 2.01e-70
AQZ69232.1 cytochrome BGC0001635.4 NRPS:Type I+PKS 38.0 93.1 228.0 2.12e-70
AFK78079.1 XiaM BGC0000666.5 terpene:Sesquiterpene 44.0 81.5 226.0 2.19e-70
CAM00071.1 6-deoxyerythronolide_B_hydroxylase_(6-DEB_hydroxylase) BGC0000055.5 PKS:Type I+saccharide:hybrid/tailoring 39.0 96.1 227.0 2.34e-70
UMP03492.1 NmvR BGC0002649.2 NRPS:Type I+PKS 39.0 93.6 227.0 3.41e-70
CAA60465.1 cytochrome_P450 BGC0001040.5 NRPS:Type I+PKS 35.0 97.7 226.0 4.64e-70
AAW49320.1 cytochrome_P450 BGC0000444.5 NRPS:Type I 37.0 96.4 226.0 5.12e-70
CCH63736.1 XiaJ_protein BGC0000665.5 terpene:Sesquiterpene+other:other 44.0 81.5 225.0 6.11e-70
AHB38510.1 EpnI BGC0000345.5 NRPS:Type I+PKS:Type I 36.0 99.0 226.0 6.75e-70
QDQ37892.1 cytochrome_P450 BGC0001979.4 PKS 37.0 93.6 226.0 7.47e-70
AZM57025.1 cytochrome_P450 BGC0002314.3 NRPS:Type I 38.0 101.3 225.0 8.48e-70
ANA09446.1 PriD BGC0001483.4 other:other 37.0 111.3 227.0 9.6e-70
EDY47130.1 cytochrome_P450-SU2 BGC0000845.5 other:non-nrp beta-lactam 37.0 99.5 225.0 1.02e-69
WP_003062297.1 cytochrome_P450 BGC0002009.4 PKS 39.0 98.5 225.0 1.1e-69
CBA11578.1 cytochrome_P450 BGC0001046.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 37.0 93.6 225.0 1.2e-69
AAU93799.1 cytochrome_P450_oxidoreductase BGC0000054.5 PKS 40.0 95.1 225.0 1.37e-69
AEZ64507.1 Herg BGC0001065.5 PKS 36.0 103.9 225.0 1.49e-69
AGS77323.1 OxyB_monooxygenase BGC0001178.5 NRPS:Type I 37.0 94.6 224.0 1.55e-69
QIZ24106.1 cytochrome_P450_monooxygenase BGC0002540.3 PKS 39.0 93.6 224.0 1.81e-69
AFV52207.1 P450_monooxygenase BGC0000081.5 NRPS:Type I+PKS:Iterative type I 38.0 96.1 224.0 2.86e-69
AAS79453.1 P450 BGC0000035.5 PKS 36.0 96.4 224.0 3.93e-69
ABY66014.1 P450_oxidoreductase BGC0001008.5 PKS:Iterative type I 37.0 99.2 224.0 4.14e-69
ANW12113.1 putative_cytochrome_P450 BGC0001374.5 other:other 37.0 97.9 223.0 4.22e-69
UMP03496.1 NmvG BGC0002649.2 NRPS:Type I+PKS 38.0 99.2 223.0 4.45e-69
BAB69197.1 cytochrome_P450 BGC0000117.5 PKS 37.0 100.3 223.0 5.09e-69
CAG15019.1 P450_monooxygenase BGC0000441.4 NRPS:Type I 40.0 81.0 221.0 8.43e-69
CAC20928.1 PimG_protein BGC0000125.5 PKS 37.0 99.7 223.0 8.59e-69
AQT01386.1 SgnG BGC0001690.5 PKS 37.0 99.7 223.0 8.59e-69
QSE03589.1 Lcm6 BGC0002333.3 PKS 38.0 97.7 222.0 1.03e-68
ABB52528.1 cytochrome_P-450 BGC0000047.5 PKS 36.0 99.0 223.0 1.09e-68
WFP21071.1 SrbH BGC0002912.1 NRPS:Type II 37.0 99.5 222.0 1.49e-68
ANC94978.1 AlmPIII BGC0001396.5 PKS 36.0 99.0 222.0 1.54e-68
WP_020275090.1 cytochrome_P450 BGC0002012.4 PKS 38.0 97.7 222.0 2.23e-68
ARG41922.1 IstS BGC0001622.5 PKS 35.0 100.5 221.0 3.22e-68
ADB02836.1 AzicO2 BGC0000202.5 PKS 37.0 99.7 221.0 3.34e-68
AGF91759.1 monooxygenase_(a.a._4&6) BGC0003168.1 NRPS:Type I+saccharide 36.0 97.4 221.0 3.38e-68
CCC55925.1 hypothetical_protein BGC0000973.5 NRPS:Type I+PKS:Type I 39.0 93.3 221.0 4.3e-68
QDQ37886.1 cytochrome_P450 BGC0001979.4 PKS 37.0 97.9 221.0 6.21e-68
OJF16276.1 AceN BGC0001491.3 PKS 40.0 100.5 220.0 8.07e-68
ALA09370.1 cytochrome_P450 BGC0001303.5 PKS 37.0 96.9 220.0 8.7e-68
MDT8911862.1 cytochrome_P450 BGC0003143.1 PKS:Type I 36.0 97.7 220.0 9.43e-68
AIG79236.1 Cytochrome_P450 BGC0000419.5 NRPS:Type I+saccharide 36.0 97.4 219.0 1.33e-67
CAE53363.1 OxyC_protein BGC0000440.5 NRPS:Type I 35.0 100.5 219.0 1.59e-67
ABP55212.1 cytochrome_P450 BGC0000142.3 PKS 37.0 96.9 219.0 1.72e-67
AKT74280.1 TxnO5 BGC0002141.3 PKS 35.0 93.6 219.0 1.78e-67
CAG15021.1 P450_monooxygenase BGC0000441.4 NRPS:Type I 35.0 100.5 219.0 2.85e-67
AAQ84152.1 PlmT4 BGC0000123.5 PKS 37.0 99.2 219.0 3e-67
QIQ28632.1 Nbc36 BGC0002541.2 other:other 38.0 93.6 218.0 4.12e-67
AZM57026.1 cytochrome_P450 BGC0002314.3 NRPS:Type I 37.0 99.5 217.0 4.83e-67
CAD91207.1 putative_OxyB_monooxigenase BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 38.0 97.4 218.0 5.21e-67
CAA11798.1 PCZA363.7 BGC0000322.3 NRPS:Type I 36.0 97.4 218.0 6.44e-67
AAS79447.1 P450 BGC0000035.5 PKS 36.0 98.5 218.0 6.62e-67
EME52985.1 cytochrome_P450_FAS1 BGC0001460.5 NRPS:Type I 35.0 97.4 218.0 7.33e-67
ADZ45320.1 cytochrome_P450 BGC0001020.5 NRPS:Type I+PKS 35.0 99.5 218.0 8.6e-67
WMD04168.1 cytochrome_P450 BGC0002988.1 PKS:Type I 36.0 100.3 217.0 1.7e-66
AAG06719.1 cytochrome_P450 BGC0002037.3 NRPS:Type I 38.0 91.3 217.0 1.75e-66
AEI58869.1 p450_monooxygenase BGC0000455.6 saccharide+NRPS:Type I 35.0 97.4 216.0 2.59e-66
CAA76548.1 P450_monooxygenase BGC0000311.6 saccharide+NRPS:Type I 35.0 97.4 216.0 2.88e-66
ABB69746.1 PlaO2 BGC0000654.4 terpene:Diterpene+saccharide:hybrid/tailoring 37.0 101.0 216.0 3.94e-66
AGS77326.1 OxyC_monooxygenase BGC0001178.5 NRPS:Type I 36.0 100.5 216.0 3.95e-66
AIE77064.1 p450_monooxygenase-like_protein BGC0000418.5 NRPS:Type I 35.0 97.4 216.0 4.05e-66
AAM80533.1 StaH BGC0000290.5 NRPS:Type I 39.0 93.3 215.0 8.02e-66
EPH46584.1 putative_Cytochrome-SU2 BGC0001519.5 NRPS:Type I+PKS 34.0 99.5 214.0 1.39e-65
QIC03956.1 CyaG BGC0002347.3 other:other 35.0 99.7 214.0 2.61e-65
ABM21740.1 PdmW BGC0000256.3 PKS 36.0 100.3 213.0 3.4e-65
BAF98633.1 putative_P450 BGC0000651.5 terpene 36.0 102.1 213.0 3.58e-65
OKA09428.1 cytochrome BGC0001459.5 NRPS:Type I 34.0 97.4 212.0 8.75e-65
ABB52539.1 cytochrome_P-450 BGC0000047.5 PKS 35.0 96.4 213.0 1.1e-64
DAC74143.1 cytochrome_P450 BGC0002019.3 terpene 38.0 98.5 211.0 1.26e-64
BAC76495.1 P450_hydroxylase_LkmK BGC0000085.5 PKS 36.0 98.5 212.0 1.44e-64
QDQ37897.1 cytochrome_P450 BGC0001979.4 PKS 36.0 100.8 212.0 1.6e-64
BAC57023.2 cytochrome_P450 BGC0000102.5 PKS 35.0 94.1 211.0 2.31e-64
QYC40294.1 Crosslinking_oxygenase_OxyB BGC0002344.2 NRPS:Type I 37.0 97.4 210.0 4.82e-64
ASZ00160.1 cytochrome_P450 BGC0001785.5 PKS 37.0 96.9 209.0 1.44e-63
ABO15884.1 cytochrome_P450 BGC0000132.3 PKS 37.0 97.4 208.0 4.47e-63
ctg1_orf525 BGC0001199.5 PKS 36.0 94.6 207.0 7.38e-63
OLZ50888.1 cytochrome BGC0001461.5 NRPS:Type I 36.0 93.1 207.0 1.04e-62
AAT12284.1 LtxB BGC0000384.6 NRPS:Type I 33.0 100.0 208.0 1.23e-62
QDQ37875.1 cytochrome_P450 BGC0001979.4 PKS 35.0 99.5 206.0 1.54e-62
BAP34719.1 cytochrome_P450 BGC0000078.5 PKS 34.0 101.0 206.0 2.21e-62
BAJ52675.1 putative_cytochrome_P450 BGC0000222.5 PKS 38.0 97.7 206.0 2.49e-62
OAP25810.1 Cytochrome_P450_107B1 BGC0001658.3 PKS 36.0 97.7 206.0 2.88e-62
AYA22329.1 OxyB BGC0001955.4 saccharide+NRPS:Type I 36.0 93.1 206.0 2.88e-62
ctg3_7 BGC0001853.3 NRPS:Type I+PKS:Type I 37.0 96.9 206.0 3.52e-62
AEI58870.1 p450_monooxygenase BGC0000455.6 saccharide+NRPS:Type I 35.0 94.9 204.0 1.38e-61
WP_010875295.1 cytochrome_P450 BGC0001605.3 terpene 33.0 101.0 204.0 1.66e-61
AIE77065.1 p450_monooxygenase-like_protein BGC0000418.5 NRPS:Type I 36.0 100.3 204.0 2.31e-61
AIG79235.1 Cytochrome_P450 BGC0000419.5 NRPS:Type I+saccharide 35.0 99.5 204.0 2.31e-61
ACB47071.1 putative_cytochrome_P450_hydroxylase BGC0001060.5 PKS 37.0 97.9 203.0 2.34e-61
QBG82535.1 cytochrome_P450 BGC0002587.2 PKS 35.0 99.5 203.0 2.97e-61
AEC13077.1 fosK BGC0000060.5 PKS 38.0 99.5 202.0 4.39e-61
ALG65320.1 Cal16 BGC0001297.4 NRPS:Type I 35.0 99.0 202.0 5.52e-61
QLD23834.1 cytochrome_P450 BGC0002086.3 PKS 33.0 99.2 202.0 6.83e-61
AKT74275.1 TxnO2 BGC0002141.3 PKS 34.0 101.5 202.0 9.36e-61
ARW71482.1 cytochrome_P450_epoxidase BGC0001812.3 PKS 33.0 99.2 202.0 9.6e-61
QBA57766.1 cytochrome_P450 BGC0002377.2 NRPS:Type I 35.0 99.0 202.0 1.09e-60
ANC94973.1 AlmPI BGC0001396.5 PKS 35.0 90.7 199.0 1.57e-60
WKD80520.1 Cytochrome_P450 BGC0002957.1 NRPS:Type I 36.0 101.8 201.0 1.63e-60
AUO16395.1 cytochrome_P450 BGC0001700.5 PKS 37.0 97.2 200.0 5.52e-60
OLZ52451.1 cytochrome BGC0001462.5 NRPS:Type I 35.0 94.6 200.0 6.42e-60
AEW98132.1 cytochrome_P450-like_enzyme BGC0002642.2 other:other 36.0 94.1 199.0 9.86e-60
ABO15856.1 cytochrome_P450 BGC0000130.5 PKS 36.0 100.8 199.0 1.57e-59
OKA09429.1 cytochrome BGC0001459.5 NRPS:Type I 34.0 93.8 198.0 2.26e-59
QDJ74279.1 cytochrome_P450 BGC0002109.3 NRPS:Type I 35.0 102.6 197.0 6.26e-59
AAM80531.1 StaJ BGC0000290.5 NRPS:Type I 34.0 99.7 196.0 8.7e-59
ACN29715.1 cytochrome_P450_hydroxylase BGC0000814.3 other:other 37.0 97.9 196.0 1.42e-58
EME52984.1 cytochrome_P450_FAS1 BGC0001460.5 NRPS:Type I 34.0 94.9 196.0 1.73e-58
ABB69759.1 PlaO4 BGC0000654.4 terpene:Diterpene+saccharide:hybrid/tailoring 33.0 100.8 195.0 3.3e-58
AQZ69231.1 hypothetical_protein BGC0001635.4 NRPS:Type I+PKS 34.0 98.2 194.0 4.19e-58
AYA22328.1 OxyC BGC0001955.4 saccharide+NRPS:Type I 33.0 95.4 194.0 6.72e-58
AGF91761.1 monooxygenase_(a.a._5&7) BGC0003168.1 NRPS:Type I+saccharide 35.0 93.8 194.0 6.72e-58
OLZ50889.1 cytochrome BGC0001461.5 NRPS:Type I 33.0 95.4 193.0 1.86e-57
ADI71453.1 putative_hydroxylase BGC0000203.3 PKS 35.0 100.3 192.0 5.14e-57
ADE22287.1 putative_cytochrome_P450_hydroxylase BGC0000279.5 PKS 36.0 96.4 191.0 8.74e-57
AGI62224.1 cytochrome_P450 BGC0001335.5 other:other 36.0 101.3 191.0 1.14e-56
CAC01489.1 putative_cytochrome_P450 BGC0002127.3 PKS 35.0 100.0 191.0 1.35e-56
QUF98526.1 cytochrome_P450 BGC0002582.3 NRPS:Type I 36.0 100.5 191.0 1.85e-56
CAE53360.1 Oxy_protein BGC0000440.5 NRPS:Type I 32.0 93.8 190.0 2.28e-56
CAG15018.1 P450_monooxygenase BGC0000441.4 NRPS:Type I 32.0 93.8 190.0 2.28e-56
AAM80534.1 StaG BGC0000290.5 NRPS:Type I 34.0 94.9 189.0 4.5e-56
AIG79237.1 Cytochrome_P450 BGC0000419.5 NRPS:Type I+saccharide 33.0 100.8 189.0 6.48e-56
AEC04353.1 cytochrome_P450 BGC0000178.5 PKS:Trans-AT type I 31.0 100.8 189.0 7.66e-56
CAA76549.1 P450_monooxygenase BGC0000311.6 saccharide+NRPS:Type I 34.0 93.1 189.0 7.71e-56
QYC40293.1 Crosslinking_oxygenase_OxyC BGC0002344.2 NRPS:Type I 32.0 100.5 188.0 1.24e-55
AIE77063.1 p450_monooxygenase-like_protein BGC0000418.5 NRPS:Type I 32.0 94.1 187.0 2.51e-55
BAL90275.1 putative_cytochrome_P450 BGC0002021.3 PKS 35.0 98.2 187.0 2.52e-55
ALV86875.1 Tlo29 BGC0001406.5 NRPS:Type I 36.0 89.5 187.0 2.91e-55
AGF91758.1 monooxygenase_(a.a._2&4) BGC0003168.1 NRPS:Type I+saccharide 32.0 99.5 187.0 5.72e-55
WP_030578062.1 cytochrome_P450 BGC0001753.3 ribosomal:RiPP 36.0 89.7 186.0 6.95e-55
CAM00567.1 cytochrome_P450 BGC0000902.4 PKS 36.0 97.9 186.0 7.29e-55
AHB38496.1 EpxC BGC0000346.5 NRPS:Type I+PKS:Type I 35.0 93.3 186.0 1.28e-54
CAF32361.1 putative_cytochrome_P450_hydroxylase BGC0000712.5 saccharide 35.0 100.5 186.0 1.36e-54
CAC20932.1 PimD_protein BGC0000125.5 PKS 34.0 101.3 185.0 1.83e-54
AQT01381.1 SgnD BGC0001690.5 PKS 34.0 101.3 185.0 1.83e-54
AAL78054.1 RppB BGC0000285.5 PKS:Type III+saccharide:oligosaccharide 36.0 97.9 185.0 2.01e-54
QBG82523.1 cytochrome_P450 BGC0002587.2 PKS 35.0 96.4 184.0 8.34e-54
CAD91209.1 putative_OxyA_monooxygenase BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 32.0 93.6 183.0 1.26e-53
ALJ49912.1 TlmF BGC0001237.5 PKS 34.0 94.6 183.0 1.77e-53
AYA22331.1 OxyA BGC0001955.4 saccharide+NRPS:Type I 31.0 99.5 182.0 2.14e-53
QCF28931.1 cytochrome_P450_hydroxylase BGC0002308.2 other:other+PKS 34.0 100.5 182.0 4.44e-53
OLZ50937.1 cytochrome BGC0001461.5 NRPS:Type I 30.0 99.5 181.0 5.92e-53
CAD91208.1 putative_monooxygenase BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 33.0 100.5 180.0 1.08e-52
AAF86397.1 FkbD BGC0000994.5 NRPS:Type I+PKS 33.0 94.9 177.0 1.26e-51
QYC40292.1 Crosslinking_oxygenase_OxyA BGC0002344.2 NRPS:Type I 31.0 95.4 176.0 5.47e-51
WP_020636808.1 cytochrome_P450 BGC0002011.3 PKS 33.0 97.9 176.0 7.21e-51
QGJ79685.1 Cytochrome_P450_monooxygenase BGC0002552.2 PKS 33.0 97.9 176.0 7.21e-51
AJO72741.1 Cytochrome_P450_monooxygenase BGC0001381.5 PKS 38.0 86.9 175.0 3.01e-50
QUF98527.1 cytochrome_P450 BGC0002582.3 NRPS:Type I 32.0 102.3 174.0 4.23e-50
ACB47070.1 putative_cytochrome_P450_hydroxylase BGC0001060.5 PKS 34.0 95.6 174.0 5.18e-50
CAI94704.1 putative_cytochrome_P450 BGC0000141.5 PKS 33.0 100.8 173.0 7.75e-50
AKQ20702.1 cytochrome_p450 BGC0001337.5 other:other 32.0 94.3 172.0 1.15e-49
ADR01067.1 NocB BGC0000609.3 ribosomal:RiPP:Thiopeptide 34.0 103.1 171.0 7.42e-49
OLZ52454.1 cytochrome BGC0001462.5 NRPS:Type I 30.0 93.3 170.0 1.14e-48
AEP40931.1 cytochrome_P450_monooxygenase BGC0000021.5 PKS 33.0 90.0 170.0 1.3e-48
WP_004562636.1 cytochrome_P450 BGC0002009.4 PKS 35.0 94.9 169.0 1.48e-48
EHK80160.1 cytochrome_p450-like_enzyme BGC0001447.3 PKS 37.0 82.3 170.0 1.82e-48
ACY01404.1 hydroxylase BGC0000083.5 PKS:Type I 34.0 96.9 169.0 5.61e-48
ACY13420.1 cytochrome_P450 BGC0001367.5 NRPS:Type I+PKS 36.0 82.0 168.0 8.65e-48
CAE53359.1 OxyA_protein BGC0000440.5 NRPS:Type I 30.0 94.3 166.0 3.25e-47
CAG15017.1 P450_monooxygenase BGC0000441.4 NRPS:Type I 30.0 94.3 166.0 3.25e-47
OEI73809.1 cytochrome_P450 BGC0002977.1 NRPS:Type I+PKS:Type I 31.0 94.3 164.0 2.7e-46
AXN93609.1 PuwJ BGC0001953.4 NRPS:Type I 33.0 94.9 164.0 5.17e-46
AGS77321.1 OxyA_monooxygenase BGC0001178.5 NRPS:Type I 30.0 93.8 162.0 6.6e-46
CBZ42154.1 putative_P450-like_enzyme BGC0001117.5 NRPS:Type I 33.0 96.1 162.0 1.05e-45
BBM96643.1 cytochrome_P450_hydroxylase BGC0002452.2 PKS 35.0 90.2 162.0 1.63e-45
AAM80535.1 StaF BGC0000290.5 NRPS:Type I 29.0 94.3 161.0 1.8e-45
WP_020636861.1 cytochrome_P450 BGC0002011.3 PKS 33.0 100.0 160.0 3.16e-45
AEO12713.1 cytochrome_P450 BGC0001334.5 other:other 39.0 75.3 161.0 3.3e-45
ABX71093.1 Lct10 BGC0000238.5 PKS 32.0 99.5 162.0 3.65e-45
ARW71481.1 cytochrome_P450_hydroxylase BGC0001812.3 PKS 34.0 89.2 161.0 3.75e-45
ctg1_16 BGC0001931.2 PKS 35.0 90.2 160.0 6.32e-45
WP_053138501.1 cytochrome_P450 BGC0002033.4 PKS 35.0 89.2 160.0 6.32e-45
QLD23833.1 cytochrome_P450 BGC0002086.3 PKS 34.0 89.2 160.0 7.31e-45
QIS94333.1 Tjp9 BGC0002482.2 other:other 35.0 89.5 160.0 1.03e-44
ABV83224.1 CppL BGC0000116.5 PKS 30.0 99.7 159.0 1.23e-44
EWS95123.1 hypothetical_protein BGC0000306.5 NRPS:Type I 34.0 93.8 159.0 1.78e-44
AKG06373.1 cytochrome_P-450 BGC0001830.3 PKS 35.0 87.1 159.0 2.5e-44
AXN93596.1 PuwJ BGC0001952.3 NRPS:Type I 32.0 94.9 158.0 5.41e-44
CAJ88188.1 putative_cytochrome_P450 BGC0000151.5 PKS:Type I+saccharide:hybrid/tailoring 33.0 99.0 157.0 8.12e-44
AHA81987.1 Arm17 BGC0000199.5 PKS:Type II+saccharide:hybrid/tailoring 33.0 95.4 157.0 8.18e-44
BCB17037.1 putative_cytochrome_P450 BGC0002523.2 NRPS:Type I 32.0 101.5 157.0 9.7e-44
QIQ28633.1 Nbc37 BGC0002541.2 other:other 34.0 86.6 156.0 3.38e-43
ACS83778.1 cytochrome_P450_monooxygenase BGC0000613.5 ribosomal:RiPP:Thiopeptide 34.0 87.4 154.0 6.68e-43
ABW00329.1 cytochrome_P450 BGC0000333.5 NRPS:Type I 33.0 88.7 154.0 1.53e-42
OWA25229.1 cytochrome_P450 BGC0001438.5 PKS+saccharide:hybrid/tailoring 32.0 90.7 151.0 1.56e-41
ABV91294.1 probable_cytochrome_P450 BGC0000158.5 PKS:Type I 36.0 79.9 152.0 2.22e-41
ADG87273.1 cytochrome_P450 BGC0001860.4 ribosomal:RiPP:Thiopeptide 33.0 87.1 150.0 2.74e-41
BBA84062.1 cytochrome_p450 BGC0001649.3 PKS 30.0 88.9 147.0 5.94e-40
QGZ36660.1 cytochrome_P450 BGC0002082.3 NRPS:Type I+PKS 34.0 77.4 146.0 1.77e-39
AAG13924.1 C-6_hydroxylase BGC0000092.5 PKS 42.0 45.2 139.0 3.17e-39
ACN29717.1 cytochrome_P450_monooxygenase BGC0000814.3 other:other 32.0 101.8 144.0 4.55e-39
AWH12925.1 StmP3 BGC0001784.5 PKS 30.0 91.3 143.0 1.09e-38
AEM00625.1 P450_monooxygenase BGC0000605.5 ribosomal:RiPP:Thiopeptide 33.0 87.7 141.0 2.07e-38
ABJ97440.1 MerD BGC0001012.3 NRPS:Type I+PKS 34.0 79.7 139.0 9.55e-38
CAG23984.1 putative_cytochrome_P450_monooxygenase BGC0000176.5 PKS 30.0 85.6 139.0 5.04e-37
ACY06266.1 cytochrome_P450_monooxygenase BGC0001042.5 NRPS:Type I+PKS 29.0 87.9 138.0 8.72e-37
ACN29722.1 cytochrome_P450 BGC0000814.3 other:other 33.0 93.6 134.0 3.82e-35
AEF33091.1 cytochrome_P450_family_protein BGC0001039.5 NRPS:Type I+PKS 29.0 95.9 133.0 9.97e-35
WP_010875296.1 cytochrome_P450 BGC0001605.3 terpene 33.0 82.5 134.0 1.25e-34
BBC27538.1 cytochrome_P450_monooxygenase BGC0001529.5 other:other 33.0 91.0 127.0 1.62e-32
CAN98721.1 Cytochrome_P450_CYP264B1 BGC0001201.3 terpene 28.0 88.7 125.0 4.94e-32
ABB88517.1 cytochrome_450_monooxygenase BGC0000050.5 PKS 32.0 94.6 122.0 8.23e-31
AAO65808.1 monensin_hydroxylase BGC0000100.5 PKS 30.0 79.4 117.0 5.11e-29
ANZ52471.1 MonD BGC0001670.5 PKS 30.0 79.4 117.0 5.11e-29
AFL48549.1 cytochrome_P450_hydroxylase BGC0000084.5 PKS 32.0 77.9 117.0 5.49e-29
UEF20583.1 nonribosomal_peptide_synthetase BGC0002360.3 NRPS:Type I 28.0 96.1 119.0 9.74e-29
QKF54440.2 P450+A+T BGC0002581.2 NRPS:Type I 28.0 96.1 119.0 9.74e-29
QDG75027.1 cytochrome_P450 BGC0002068.3 NRPS:Type I+PKS 29.0 77.6 116.0 1.38e-28
AEU17896.1 putative_P450_oxygenase BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 27.0 103.1 115.0 4.04e-28
OLZ50900.1 NikQ_protein BGC0001461.5 NRPS:Type I 27.0 94.1 110.0 1.36e-26
AYA22317.1 OxyD BGC0001955.4 saccharide+NRPS:Type I 27.0 94.1 110.0 1.36e-26
UID85536.1 biotin_biosynthesis_cytochrome_P450 BGC0002631.2 ribosomal:RiPP:Biarylitide 30.0 88.2 110.0 1.63e-26
WP_235558178.1 cytochrome_P450 BGC0001653.3 PKS 31.0 92.5 112.0 2.44e-26
AKA59441.1 cytochrome_P450_hydroxylase BGC0001202.4 NRPS:Type I+PKS 27.0 102.6 109.0 3.71e-26
CCH32732.1 Cytochrome_P450_monooxygenase BGC0002070.3 PKS 31.0 77.4 106.0 2.99e-25
AIG79223.1 Hypothetical_protein BGC0000419.5 NRPS:Type I+saccharide 26.0 93.6 106.0 4.29e-25
AIE77077.1 p450_monooxygenase BGC0000418.5 NRPS:Type I 27.0 89.2 103.0 3.82e-24
AEI58880.1 p450_monooxygenase BGC0000455.6 saccharide+NRPS:Type I 26.0 94.1 103.0 3.82e-24
OKA09437.1 NikQ_protein BGC0001459.5 NRPS:Type I 25.0 88.7 100.0 6.22e-23
BAB69191.1 P450-like_protein BGC0000117.5 PKS 48.0 26.0 89.0 3.76e-21
BAR97459.1 hypothetical_protein BGC0001911.3 terpene 28.0 97.2 95.0 4.64e-21
AJW65400.1 cytochrome_P450_monooxygenase BGC0001195.3 NRPS:Type I+PKS 27.0 89.5 91.0 1.1e-19
ACN52301.1 TsrK BGC0000614.5 ribosomal:RiPP:Thiopeptide 30.0 97.9 91.0 1.31e-19
QRM13816.1 putative_cytochrome_P450 BGC0002099.3 ribosomal:unmodified 31.0 82.8 87.0 1.71e-18
QRM13814.1 putative_cytochrome_P450 BGC0002084.4 ribosomal:unmodified 31.0 82.8 82.0 8.49e-17
NP_391386.1 cyclo-L-leucyl-L-leucyl_dipeptide_oxidase,_pulcheriminic_synthase BGC0002103.2 other:other 23.0 97.7 80.0 4.43e-16
UHY14094.1 cytochrome_P450 BGC0002996.1 NRPS:Type I 21.0 98.7 68.0 6.32e-12
OAQ83755.1 isotrichodermin_C-15_hydroxylase BGC0001358.4 NRPS:Type I+PKS 27.0 49.4 51.0 1.72e-06
ABD59215.1 InkP BGC0000813.3 other:other 34.0 34.4 48.0 2.85e-06